PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12077187-0 2002 Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. polyglutamine 0-13 ataxin 7 Mus musculus 23-31 12077187-1 2002 Spinocerebellar ataxia (SCA) type 7 is an inherited neurodegenerative disorder caused by expansion of a polyglutamine tract within the ataxin-7 protein. polyglutamine 104-117 ataxin 7 Mus musculus 135-143 12077187-5 2002 We also detected an N-terminal truncation fragment of ataxin-7 in transgenic mice and in SCA7 patient material with both anti-ataxin-7 and anti-polyglutamine specific antibodies. polyglutamine 144-157 ataxin 7 Mus musculus 54-62 12077187-7 2002 The non-cell-autonomous nature of the Purkinje cell degeneration in our SCA7 mouse model indicates that polyglutamine-induced dysfunction in adjacent or connecting cell types contributes to the neurodegeneration. polyglutamine 104-117 ataxin 7 Mus musculus 72-76