PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12014310-8 2002 In these patients, after 8 days, clonidine decreases sympathetic activity, increases glomerular filtration rate and after 18 days, decreases plasma renin and aldosterone concentrations allowing a better action of spironolactone. Clonidine 33-42 renin Homo sapiens 148-153