PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11992633-0 2002 7-Benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine, a potent inhibitor of cAMP-specific phosphodiesterase, enhancing nuclear protein binding to the CRE consensus sequence in human tumour cells. 8-chloro-cyclic adenosine monophosphate 83-87 regulating synaptic membrane exocytosis 2 Homo sapiens 126-141 11992633-1 2002 The cAMP-specific phosphodiesterase isoenzyme family PDE4 represents the highest cAMP-hydrolysing activity in many human cancer cell lines including the human large cell lung carcinoma cell line LXFL529L. 8-chloro-cyclic adenosine monophosphate 4-8 phosphodiesterase 4A Homo sapiens 53-57 11992633-1 2002 The cAMP-specific phosphodiesterase isoenzyme family PDE4 represents the highest cAMP-hydrolysing activity in many human cancer cell lines including the human large cell lung carcinoma cell line LXFL529L. 8-chloro-cyclic adenosine monophosphate 81-85 phosphodiesterase 4A Homo sapiens 53-57 11992633-5 2002 DC-TA-46 mediated inhibition of PDE4 activity in LXFL529L cells resulted in an increase of the intracellular cAMP level and significant induction of the activity of protein kinase A (PKA). 8-chloro-cyclic adenosine monophosphate 109-113 phosphodiesterase 4A Homo sapiens 32-36