PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11948540-6 2002 The CYP3A2 antisense 22-mer AVI-4472 (5"-GAGCTGAAAGCAGGTCCATCCC-3") caused a sequence-dependent reduction of approximately five-fold in the rat liver CYP3A2 protein levels and erythromycin demethylation activity in 24 h following oral administration at a dose of 2 mg/kg. Erythromycin 176-188 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 4-10 11948540-7 2002 It is concluded that oral administration of PMOs can inhibit c-myc and CYP3A2 gene expression in rat liver by an antisense-based mechanism of action. pmos 44-48 MYC proto-oncogene, bHLH transcription factor Rattus norvegicus 61-66 11948540-7 2002 It is concluded that oral administration of PMOs can inhibit c-myc and CYP3A2 gene expression in rat liver by an antisense-based mechanism of action. pmos 44-48 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 71-77