PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11882577-1 2002 Interleukin-1beta (IL-1beta), a proinflammatory cytokine, induces cyclooxygenase-2 (COX-2) in cultured neonatal ventricular myocytes (NVMs), resulting in the preferential production of prostaglandin E(2) (PGE(2)). Prostaglandins E 205-208 mitochondrially encoded cytochrome c oxidase II Homo sapiens 84-89 11882577-11 2002 We concluded that (1) PGE(2) production requires the induction of its specific synthase; (2) in myocytes, the inducible enzymes COX-2 and PGES are perinuclear; and (3) PGE(2) and sulprostone induce cardiac myocyte growth but seem to activate a different subset of EP receptors. Prostaglandins E 22-25 mitochondrially encoded cytochrome c oxidase II Homo sapiens 128-133