PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11786475-0 2002 CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord. Capsaicin 46-55 cannabinoid receptor 1 (brain) Mus musculus 0-5 11786475-2 2002 We have investigated a possible modulatory role for Type 1 Cannabinoid receptors (CB(1)) on the release of excitatory transmitter Substance P from the adult mouse spinal cord after stimulation of nociceptor terminals by capsaicin. Capsaicin 220-229 cannabinoid receptor 1 (brain) Mus musculus 82-87 11786475-6 2002 Superfusion of CB(1) antagonist SR141716A (5 microM) increased evoked SP release with capsaicin (0.1 - 10 microM) and reversed the reducing effect of high dose capsaicin (100 microM). Capsaicin 86-95 cannabinoid receptor 1 (brain) Mus musculus 15-20 11786475-6 2002 Superfusion of CB(1) antagonist SR141716A (5 microM) increased evoked SP release with capsaicin (0.1 - 10 microM) and reversed the reducing effect of high dose capsaicin (100 microM). Capsaicin 160-169 cannabinoid receptor 1 (brain) Mus musculus 15-20 11786475-7 2002 Antagonism of CB(1) receptors in the spinal cord during capsaicin stimulation, is evidence of tonic CB(1) activity inhibiting the release of excitatory transmitters after activation of nociceptive neurones and is also indicative of endocannabinoid production during noxious stimulation. Capsaicin 56-65 cannabinoid receptor 1 (brain) Mus musculus 14-19 11786475-7 2002 Antagonism of CB(1) receptors in the spinal cord during capsaicin stimulation, is evidence of tonic CB(1) activity inhibiting the release of excitatory transmitters after activation of nociceptive neurones and is also indicative of endocannabinoid production during noxious stimulation. Capsaicin 56-65 cannabinoid receptor 1 (brain) Mus musculus 100-105