PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11598110-7 2001 Interestingly, the H(2)O(2)-induced activation of Akt was entirely mediated by upstream stimulation of PI 3"-kinase activity, since treatment of 3T3-L1 adipocytes with the PI 3"-kinase inhibitors wortmannin or LY294002 completely blocked the subsequent activation of Akt by exogenous H(2)O(2). Hydrogen Peroxide 19-27 AKT serine/threonine kinase 1 Homo sapiens 50-53 11598110-7 2001 Interestingly, the H(2)O(2)-induced activation of Akt was entirely mediated by upstream stimulation of PI 3"-kinase activity, since treatment of 3T3-L1 adipocytes with the PI 3"-kinase inhibitors wortmannin or LY294002 completely blocked the subsequent activation of Akt by exogenous H(2)O(2). Hydrogen Peroxide 19-27 AKT serine/threonine kinase 1 Homo sapiens 267-270