PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11581570-10 2001 According to the current model, the specific cellular recognition of agonistic LPS/lipid A is initialized by the combined extracellular actions of LPS binding protein (LBP), the membrane-bound or soluble forms of CD14 and the newly identified Toll-like receptor 4 (TLR4)*MD-2 complex, leading to the rapid activation of an intracellular signaling network that is highly homologous to the signaling systems of IL-1 and IL-18. Lipid A 83-90 CD14 molecule Homo sapiens 213-217