PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11491658-0	2001	Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation.	Disulfides	73-82	ret proto-oncogene	Homo sapiens	38-41	
11491658-2	2001	A few percentage of RET proteins normally formed disulfide-bonded dimers in the cell, and osmotic stress promoted formation of these dimers.	Disulfides	49-58	ret proto-oncogene	Homo sapiens	20-23	
11491658-4	2001	Osmotic stress also promoted activation and disulfide-bonded dimerization of the extracellular domain-depleted mutant RET (RET-PTC-1), suggesting that the target amino acid(s) for dimerization is located intracellularly rather than in the cysteine-rich region of the extracellular domain.	Disulfides	44-53	ret proto-oncogene	Homo sapiens	118-121	
11491658-4	2001	Osmotic stress also promoted activation and disulfide-bonded dimerization of the extracellular domain-depleted mutant RET (RET-PTC-1), suggesting that the target amino acid(s) for dimerization is located intracellularly rather than in the cysteine-rich region of the extracellular domain.	Disulfides	44-53	ret proto-oncogene	Homo sapiens	123-126