PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11193883-6 2000 VIP/PACAP binding to VPAC1 induces both a cAMP-dependent and a cAMP-independent pathways that regulate cytokine and NO production at the transcriptional level. Cyclic AMP 42-46 adenylate cyclase activating polypeptide 1 Mus musculus 4-9 11193883-6 2000 VIP/PACAP binding to VPAC1 induces both a cAMP-dependent and a cAMP-independent pathways that regulate cytokine and NO production at the transcriptional level. Cyclic AMP 63-67 adenylate cyclase activating polypeptide 1 Mus musculus 4-9 11193883-9 2000 Whereas the inhibition of IRF-1 and CRE-binding complexes seems to be mediated through the cAMP-dependent pathway, VIP/PACAP inhibition of NFkB nuclear translocation is mediated through a reduction in IkB alpha degradation mediated by the cAMP-independent pathway. Cyclic AMP 239-243 adenylate cyclase activating polypeptide 1 Mus musculus 119-124