PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10973244-0 2000 Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. polyglutamine 9-22 cAMP responsive element binding protein 1 Homo sapiens 74-78 10973244-3 2000 We found that expanded polyQ stretches preferentially bind to TAFII130, a coactivator involved in cAMP-responsive element binding protein (CREB)-dependent transcriptional activation, and strongly suppress CREB-dependent transcriptional activation. polyglutamine 23-28 cAMP responsive element binding protein 1 Homo sapiens 98-137 10973244-3 2000 We found that expanded polyQ stretches preferentially bind to TAFII130, a coactivator involved in cAMP-responsive element binding protein (CREB)-dependent transcriptional activation, and strongly suppress CREB-dependent transcriptional activation. polyglutamine 23-28 cAMP responsive element binding protein 1 Homo sapiens 139-143 10973244-3 2000 We found that expanded polyQ stretches preferentially bind to TAFII130, a coactivator involved in cAMP-responsive element binding protein (CREB)-dependent transcriptional activation, and strongly suppress CREB-dependent transcriptional activation. polyglutamine 23-28 cAMP responsive element binding protein 1 Homo sapiens 205-209 10973244-4 2000 The suppression of CREB-dependent transcription and the cell death induced by polyQ stretches were restored by the co-expression of TAFII130. polyglutamine 78-83 cAMP responsive element binding protein 1 Homo sapiens 19-23