PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10702251-0 2000 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. 4-hydroxyretinoic acid 0-22 UDP glucuronosyltransferase family 2 member B7 Homo sapiens 116-122 10702251-7 2000 We have also determined that human recombinant UGT2B7 can glucuronidate atRA, 4-OH-RA, and 4-OH-RAc with activities similar to those found in human liver microsomes. Tretinoin 72-76 UDP glucuronosyltransferase family 2 member B7 Homo sapiens 47-53 10702251-7 2000 We have also determined that human recombinant UGT2B7 can glucuronidate atRA, 4-OH-RA, and 4-OH-RAc with activities similar to those found in human liver microsomes. 4-oh-ra 78-85 UDP glucuronosyltransferase family 2 member B7 Homo sapiens 47-53 10702251-7 2000 We have also determined that human recombinant UGT2B7 can glucuronidate atRA, 4-OH-RA, and 4-OH-RAc with activities similar to those found in human liver microsomes. 4-oh-rac 91-99 UDP glucuronosyltransferase family 2 member B7 Homo sapiens 47-53 10702251-9 2000 We also propose that atRA induces its own oxidative metabolism via a cytochrome P450 (CYP26) and is further biotransformed into glucuronides via UGT-mediated pathways. Tretinoin 21-25 cytochrome P450 family 26 subfamily A member 1 Homo sapiens 86-91