PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10652584-6 1999 SA, as well as indomethacin (INDO), reduced the synthesis of IL-6 and -11, at both the protein and mRNA levels, in the two cell lines producing these cytokines (MDA-MB-231 and Hs578T). Indomethacin 15-27 interleukin 6 Homo sapiens 61-73 10652584-6 1999 SA, as well as indomethacin (INDO), reduced the synthesis of IL-6 and -11, at both the protein and mRNA levels, in the two cell lines producing these cytokines (MDA-MB-231 and Hs578T). Indomethacin 29-33 interleukin 6 Homo sapiens 61-73 10652584-7 1999 This latter effect seemed to be mediated by PGE2 since SA and INDO reduced PGE2 levels in MDA-MB-231 and Hs578T cells, PGE2 was not detected in MCF-7 and T-47D cells and exogenous PGE2 increased IL-6 and -11 expression by MDA-MB-231 cells. Indomethacin 62-66 interleukin 6 Homo sapiens 195-207