PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10561698-1 1999 CDP-choline is a rate-limiting intermediate in the biosynthesis of phosphatidylcholine (PtdCho), an important component of the neural cell membrane. Phosphatidylcholines 67-86 cut like homeobox 1 Homo sapiens 0-3 10561698-1 1999 CDP-choline is a rate-limiting intermediate in the biosynthesis of phosphatidylcholine (PtdCho), an important component of the neural cell membrane. Phosphatidylcholines 88-94 cut like homeobox 1 Homo sapiens 0-3 10561698-3 1999 Exogenous treatment with CDP-choline stimulates PtdCho synthesis and prevents release of free fatty acids (FFA), especially arachidonic acid (AA), after ischemia/reperfusion. Phosphatidylcholines 48-54 cut like homeobox 1 Homo sapiens 25-28 10561698-10 1999 CDP-choline may act by increasing PtdCho synthesis via two pathways: (1) conversion of 1, 2-diacylglycerol to PtdCho, and (2) biosynthesis of S-adenosyl-L-methionine, thus stabilizing the membrane and reducing AA release and metabolism to leukotriene C(4). Phosphatidylcholines 34-40 cut like homeobox 1 Homo sapiens 0-3 10561698-10 1999 CDP-choline may act by increasing PtdCho synthesis via two pathways: (1) conversion of 1, 2-diacylglycerol to PtdCho, and (2) biosynthesis of S-adenosyl-L-methionine, thus stabilizing the membrane and reducing AA release and metabolism to leukotriene C(4). Phosphatidylcholines 110-116 cut like homeobox 1 Homo sapiens 0-3