PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10397243-0	1999	Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway.	Arsenic	0-7	tumor protein p53	Homo sapiens	73-76	
10397243-5	1999	In contrast, arsenic-induced apoptosis was almost totally blocked by expression of a dominant-negative mutant of JNK1.	Arsenic	13-20	mitogen-activated protein kinase 8	Homo sapiens	113-117	
10397243-7	1999	Taken together with previous findings that p53 mutations are involved in approximately 50% of all human cancers and nearly all chemotherapeutic agents kill cancer cells mainly by apoptotic induction, we suggest that arsenic may be a useful agent for the treatment of cancers with p53 mutation.	Arsenic	216-223	tumor protein p53	Homo sapiens	43-46	
10397243-7	1999	Taken together with previous findings that p53 mutations are involved in approximately 50% of all human cancers and nearly all chemotherapeutic agents kill cancer cells mainly by apoptotic induction, we suggest that arsenic may be a useful agent for the treatment of cancers with p53 mutation.	Arsenic	216-223	tumor protein p53	Homo sapiens	280-283