PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10386583-3 1999 CYP3A4-transfected microsomes had the most effective potential of nitric oxide formation from isosorbide dinitrate. Nitric Oxide 66-78 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 0-6 10386583-3 1999 CYP3A4-transfected microsomes had the most effective potential of nitric oxide formation from isosorbide dinitrate. Isosorbide Dinitrate 94-114 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 0-6 10386583-4 1999 Anti-CYP3A2 antibody (which cross-reacts with CYP3A4) or ketoconazole (an inhibitor of the CYP3A superfamily) inhibited nitric oxide formation from isosorbide dinitrate in rat heart microsomes. Nitric Oxide 120-132 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 5-11 10386583-4 1999 Anti-CYP3A2 antibody (which cross-reacts with CYP3A4) or ketoconazole (an inhibitor of the CYP3A superfamily) inhibited nitric oxide formation from isosorbide dinitrate in rat heart microsomes. Nitric Oxide 120-132 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 46-52 10386583-4 1999 Anti-CYP3A2 antibody (which cross-reacts with CYP3A4) or ketoconazole (an inhibitor of the CYP3A superfamily) inhibited nitric oxide formation from isosorbide dinitrate in rat heart microsomes. Isosorbide Dinitrate 148-168 cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus 5-11 10386583-4 1999 Anti-CYP3A2 antibody (which cross-reacts with CYP3A4) or ketoconazole (an inhibitor of the CYP3A superfamily) inhibited nitric oxide formation from isosorbide dinitrate in rat heart microsomes. Isosorbide Dinitrate 148-168 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 46-52 10386583-6 1999 These results suggest that the CYP3A4-NADPH-cytochrome P450 reductase system specifically participates in nitric oxide formation from isosorbide dinitrate. Nitric Oxide 106-118 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 31-37 10386583-6 1999 These results suggest that the CYP3A4-NADPH-cytochrome P450 reductase system specifically participates in nitric oxide formation from isosorbide dinitrate. Isosorbide Dinitrate 134-154 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 31-37