PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10363967-2 1999 Evidence for MRP-mediated antifolate efflux relies upon the following findings: (a) a 2-3.3-fold lower accumulation of [3H]MTX and subsequent reduced formation of long-chain polyglutamate forms of MTX; (b) reversal of MTX resistance by probenecid in both transfectants, and (c) ATP-dependent uptake of [3H]MTX in inside-out vesicles of MRP1 and MRP2 transfectants. Probenecid 236-246 ATP binding cassette subfamily C member 1 Homo sapiens 13-16