PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10344756-0	1999	Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.	Tetradecanoylphorbol Acetate	28-64	KRAS proto-oncogene, GTPase	Homo sapiens	10-16	
10344756-0	1999	Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.	Tetradecanoylphorbol Acetate	28-64	mitogen-activated protein kinase 8	Homo sapiens	91-116	
10344756-2	1999	Using gene targeting, we examined HCT116 cells that contain the Gly-13-->Asp mutation of Ki-ras and activated Ki-ras-disrupted clones derived from HCT116.	Aspartic Acid	76-79	KRAS proto-oncogene, GTPase	Homo sapiens	92-98	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	0-36	PYD and CARD domain containing	Homo sapiens	79-83	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	0-36	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	89-94	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	0-36	early growth response 1	Homo sapiens	100-105	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	0-36	KRAS proto-oncogene, GTPase	Homo sapiens	119-125	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	0-36	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	82-87	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	38-41	PYD and CARD domain containing	Homo sapiens	79-83	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	38-41	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	89-94	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	38-41	early growth response 1	Homo sapiens	100-105	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	38-41	KRAS proto-oncogene, GTPase	Homo sapiens	119-125	
10344756-3	1999	12-O-Tetradecanoylphorbol-13-acetate (TPA) induced immediate early genes, such as c-Jun, c-Fos, and Egr-1 in activated Ki-ras-disrupted clones, whereas c-Jun induction was rare in HCT116.	Tetradecanoylphorbol Acetate	38-41	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	82-87	
10344756-4	1999	TPA induced both phosphorylation of stress-activated protein kinase kinase 1 (SEK1) and c-Jun NH2-terminal kinase (JNK) in the activated Ki-ras-disrupted clones but not in HCT116.	Tetradecanoylphorbol Acetate	0-3	mitogen-activated protein kinase kinase 4	Homo sapiens	36-76	
10344756-4	1999	TPA induced both phosphorylation of stress-activated protein kinase kinase 1 (SEK1) and c-Jun NH2-terminal kinase (JNK) in the activated Ki-ras-disrupted clones but not in HCT116.	Tetradecanoylphorbol Acetate	0-3	mitogen-activated protein kinase kinase 4	Homo sapiens	78-82	
10344756-4	1999	TPA induced both phosphorylation of stress-activated protein kinase kinase 1 (SEK1) and c-Jun NH2-terminal kinase (JNK) in the activated Ki-ras-disrupted clones but not in HCT116.	Tetradecanoylphorbol Acetate	0-3	mitogen-activated protein kinase 8	Homo sapiens	88-113	
10344756-4	1999	TPA induced both phosphorylation of stress-activated protein kinase kinase 1 (SEK1) and c-Jun NH2-terminal kinase (JNK) in the activated Ki-ras-disrupted clones but not in HCT116.	Tetradecanoylphorbol Acetate	0-3	mitogen-activated protein kinase 8	Homo sapiens	115-118	
10344756-4	1999	TPA induced both phosphorylation of stress-activated protein kinase kinase 1 (SEK1) and c-Jun NH2-terminal kinase (JNK) in the activated Ki-ras-disrupted clones but not in HCT116.	Tetradecanoylphorbol Acetate	0-3	KRAS proto-oncogene, GTPase	Homo sapiens	137-143	
10344756-5	1999	On the other hand, TPA-induced mitogen-activated protein kinase kinase 1/2 (MEK1/2)-extracellular signal-regulated kinase (ERK) activation was equally induced between HCT116 and the Ki-ras-disrupted clones.	Tetradecanoylphorbol Acetate	19-22	mitogen-activated protein kinase kinase 1	Homo sapiens	31-74	
10344756-5	1999	On the other hand, TPA-induced mitogen-activated protein kinase kinase 1/2 (MEK1/2)-extracellular signal-regulated kinase (ERK) activation was equally induced between HCT116 and the Ki-ras-disrupted clones.	Tetradecanoylphorbol Acetate	19-22	mitogen-activated protein kinase kinase 1	Homo sapiens	76-82	
10344756-5	1999	On the other hand, TPA-induced mitogen-activated protein kinase kinase 1/2 (MEK1/2)-extracellular signal-regulated kinase (ERK) activation was equally induced between HCT116 and the Ki-ras-disrupted clones.	Tetradecanoylphorbol Acetate	19-22	mitogen-activated protein kinase 1	Homo sapiens	123-126	
10344756-5	1999	On the other hand, TPA-induced mitogen-activated protein kinase kinase 1/2 (MEK1/2)-extracellular signal-regulated kinase (ERK) activation was equally induced between HCT116 and the Ki-ras-disrupted clones.	Tetradecanoylphorbol Acetate	19-22	KRAS proto-oncogene, GTPase	Homo sapiens	182-188	
10344756-6	1999	Furthermore, TPA-induced SEK1-JNK activation was observed in a DLD-1-derived activated Ki-ras-disrupted clone but not in DLD-1.	Tetradecanoylphorbol Acetate	13-16	mitogen-activated protein kinase kinase 4	Homo sapiens	25-29	
10344756-6	1999	Furthermore, TPA-induced SEK1-JNK activation was observed in a DLD-1-derived activated Ki-ras-disrupted clone but not in DLD-1.	Tetradecanoylphorbol Acetate	13-16	mitogen-activated protein kinase 8	Homo sapiens	30-33	
10344756-6	1999	Furthermore, TPA-induced SEK1-JNK activation was observed in a DLD-1-derived activated Ki-ras-disrupted clone but not in DLD-1.	Tetradecanoylphorbol Acetate	13-16	KRAS proto-oncogene, GTPase	Homo sapiens	87-93	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	Tetradecanoylphorbol Acetate	4-7	mitogen-activated protein kinase kinase 4	Homo sapiens	16-20	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	Tetradecanoylphorbol Acetate	4-7	mitogen-activated protein kinase 8	Homo sapiens	21-24	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	Tetradecanoylphorbol Acetate	4-7	mitogen-activated protein kinase kinase 1	Homo sapiens	220-226	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	Tetradecanoylphorbol Acetate	4-7	mitogen-activated protein kinase 1	Homo sapiens	227-230	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	bisindolylmaleimide I	128-137	mitogen-activated protein kinase kinase 4	Homo sapiens	16-20	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	bisindolylmaleimide I	128-137	mitogen-activated protein kinase 8	Homo sapiens	21-24	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	bisindolylmaleimide I	128-137	mitogen-activated protein kinase kinase 1	Homo sapiens	220-226	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	bisindolylmaleimide I	128-137	mitogen-activated protein kinase 1	Homo sapiens	227-230	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	Tetradecanoylphorbol Acetate	208-211	mitogen-activated protein kinase kinase 4	Homo sapiens	16-20	
10344756-7	1999	The TPA-induced SEK1-JNK activation in these disrupted clones was completely inhibited by the protein kinase C (PKC) inhibitor, GF109203X (1 microM), but not by another PKC inhibitor, H7 (50 microM), whereas TPA-induced MEK1/2-ERK activation was partially and completely inhibited by GF109203X (1 microM) and H7 (50 microM), respectively.	bisindolylmaleimide I	284-293	mitogen-activated protein kinase kinase 4	Homo sapiens	16-20