PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10319729-5 1999 Inhibition of the MAPK pathway by use of the specific MEK1/2 inhibitor (10 microM PD98059) in both HL60/pCEP4 and HL60/Bcl-2 cells prior to irradiation permitted a similar prolonged radiation-induced activation of JNK1. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 82-89 mitogen-activated protein kinase kinase 1 Homo sapiens 54-60 10319729-5 1999 Inhibition of the MAPK pathway by use of the specific MEK1/2 inhibitor (10 microM PD98059) in both HL60/pCEP4 and HL60/Bcl-2 cells prior to irradiation permitted a similar prolonged radiation-induced activation of JNK1. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 82-89 BCL2 apoptosis regulator Homo sapiens 119-124 10319729-5 1999 Inhibition of the MAPK pathway by use of the specific MEK1/2 inhibitor (10 microM PD98059) in both HL60/pCEP4 and HL60/Bcl-2 cells prior to irradiation permitted a similar prolonged radiation-induced activation of JNK1. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 82-89 mitogen-activated protein kinase 8 Homo sapiens 214-218 10319729-7 1999 Reduced proliferation after combined irradiation and PD98059 treatment in both cell types correlated with reduced Cdc2 activity and arrest in G2/M phase of the cell cycle. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 53-60 cyclin dependent kinase 1 Homo sapiens 114-118