PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10229192-5	1999	The increase of Tiam1 mRNA was transient but the level of Tiam1 protein continued to increase at least for 6 h. In addition, the activities of Rac1 and p21-activated kinase (PAK) were also stimulated by bufalin treatment.	bufalin	203-210	TIAM Rac1 associated GEF 1	Homo sapiens	16-21	
10229192-5	1999	The increase of Tiam1 mRNA was transient but the level of Tiam1 protein continued to increase at least for 6 h. In addition, the activities of Rac1 and p21-activated kinase (PAK) were also stimulated by bufalin treatment.	bufalin	203-210	TIAM Rac1 associated GEF 1	Homo sapiens	58-63	
10229192-5	1999	The increase of Tiam1 mRNA was transient but the level of Tiam1 protein continued to increase at least for 6 h. In addition, the activities of Rac1 and p21-activated kinase (PAK) were also stimulated by bufalin treatment.	bufalin	203-210	Rac family small GTPase 1	Homo sapiens	143-147	
10229192-7	1999	Apoptosis was strongly induced by bufalin in cells that expressed sense RNA for Tiam1 as compared to apoptosis in control cells treated with bufalin only.	bufalin	34-41	TIAM Rac1 associated GEF 1	Homo sapiens	80-85	
10229192-10	1999	These results suggest that Tiaml might play a critical role in bufalin-induced apoptosis through the activation of Rac1, PAK, and JNK pathway.	bufalin	63-70	Rac family small GTPase 1	Homo sapiens	115-119	
10229192-10	1999	These results suggest that Tiaml might play a critical role in bufalin-induced apoptosis through the activation of Rac1, PAK, and JNK pathway.	bufalin	63-70	mitogen-activated protein kinase 8	Homo sapiens	130-133