PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10092072-10 1999 We conclude that addition of the phytosterol mixture (2% w/w) to a Western-type diet in apolipoprotein E-deficient mice significantly decreases plasma and hepatic cholesterol concentrations, increases hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity, and prevents cutaneous xanthomatosis and vacuolation in the parenchymal cells of kidneys and livers. Cholesterol 163-174 apolipoprotein E Mus musculus 88-104