PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10037172-0	1999	Increased activator protein-1 DNA binding and c-Jun NH2-terminal kinase activity in human breast tumors with acquired tamoxifen resistance.	Tamoxifen	118-127	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	10-29	
10037172-0	1999	Increased activator protein-1 DNA binding and c-Jun NH2-terminal kinase activity in human breast tumors with acquired tamoxifen resistance.	Tamoxifen	118-127	mitogen-activated protein kinase 8	Homo sapiens	46-71	
10037172-3	1999	ER can interact with the activator protein-1 (AP-1) transcription factor complex through protein-protein interactions that are independent of ER DNA binding and, in certain ER-positive cells, this may allow TAM to exert an agonist response on AP-1-regulated genes.	Tamoxifen	207-210	estrogen receptor 1	Homo sapiens	0-2	
10037172-3	1999	ER can interact with the activator protein-1 (AP-1) transcription factor complex through protein-protein interactions that are independent of ER DNA binding and, in certain ER-positive cells, this may allow TAM to exert an agonist response on AP-1-regulated genes.	Tamoxifen	207-210	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	25-44	
10037172-3	1999	ER can interact with the activator protein-1 (AP-1) transcription factor complex through protein-protein interactions that are independent of ER DNA binding and, in certain ER-positive cells, this may allow TAM to exert an agonist response on AP-1-regulated genes.	Tamoxifen	207-210	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	46-50	
10037172-3	1999	ER can interact with the activator protein-1 (AP-1) transcription factor complex through protein-protein interactions that are independent of ER DNA binding and, in certain ER-positive cells, this may allow TAM to exert an agonist response on AP-1-regulated genes.	Tamoxifen	207-210	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	243-247	
10037172-5	1999	AP-1 DNA binding activity was measured from cryopreserved tumor extracts using a labeled oligonucleotide probe containing a consensus AP-1 response element by electrophoretic mobility shift assay.	Oligonucleotides	89-104	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	0-4	
10037172-6	1999	JNK was first extracted from the tumor lysates by incubation over a Sepharose-bound c-Jun(1-89) fusion protein, and its activity was then measured by chemiluminescent Western blot by detection of the phosphorylated product using a phospho-Jun(Ser-63)-specific primary antibody.	Sepharose	68-77	mitogen-activated protein kinase 8	Homo sapiens	0-3	
10037172-6	1999	JNK was first extracted from the tumor lysates by incubation over a Sepharose-bound c-Jun(1-89) fusion protein, and its activity was then measured by chemiluminescent Western blot by detection of the phosphorylated product using a phospho-Jun(Ser-63)-specific primary antibody.	Serine	243-246	mitogen-activated protein kinase 8	Homo sapiens	0-3