PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 19043785-6 2009 The applicability of the method was demonstrated by MPN-enumerating mono- and di-aromatic degraders in soils of varying hydrocarbon pre-exposure. Hydrocarbons 120-131 serine protease 27 Homo sapiens 52-55 19586004-1 2009 The magnetically induced current densities for ring-shaped hydrocarbons are studied at the density functional theory (DFT) and second-order Moller-Plesset (MP2) levels using gauge-including atomic orbitals. Hydrocarbons 59-71 tryptase pseudogene 1 Homo sapiens 156-159 19774279-5 2009 Polyols with their hydroxyl groups distributed along the hydrocarbon backbone in an all-syn configuration are highly rigid and form an extended quasi 1-dimensional hydrogen-bond wire that is stable for tens of picoseconds. Hydrocarbons 57-68 synemin Homo sapiens 88-91 19452436-6 2009 TGH also induced QR activity in BPrc1 mouse hepatocarcinoma cells as well, which are defective in aryl hydrocarbon nuclear translocator (Arnt). Hydrocarbons 103-114 aryl hydrocarbon receptor nuclear translocator Mus musculus 137-141 19796483-2 2009 The C18 non-polar sorbent is placed inside the sensor and is able to retain hydrocarbons from water samples. Hydrocarbons 76-88 Bardet-Biedl syndrome 9 Homo sapiens 4-7 21217854-2 2009 Solvent Yellow 14, CAS No: 842-07-9] is used as the compound employed in chemical industry and to color materials such as hydrocarbon solvents, oils, fats, waxes, plastics, printing inks, shoe and floor polishes and gasoline. Hydrocarbons 122-133 BCAR1 scaffold protein, Cas family member Homo sapiens 19-22 19469501-9 2009 In those reactions, the key mechanistic steps require hydrogen abstraction from a beta-carbon of the hydrocarbon chain (the second when counting away from the surface), and selectivity is defined by steric considerations around the different hydrogens available at those positions. Hydrocarbons 101-112 amyloid beta precursor protein Homo sapiens 80-86 19652700-4 2009 Long-chain cuticular hydrocarbons (e.g., dienes) are produced female-specifically, notably via the activity of the desaturase DESAT-F, and are potent pheromones for male courtship behavior in Drosophila melanogaster. Hydrocarbons 21-33 Desaturase 1 Drosophila melanogaster 115-125 19182999-3 2009 New definitions are introduced, and a consistent hierarchy of reaction classes (RC1-RC5) for hydrocarbons is constructed: isogyric (RC1) superset of isodesmic (RC2) superset of hypohomodesmotic (RC3) superset of homodesmotic (RC4) superset of hyperhomodesmotic (RC5). Hydrocarbons 93-105 chromobox 8 Homo sapiens 80-87 19548727-8 2009 Hydrogen sulfide interacts more strongly than water with the hydrocarbons studied, leading to a limiting value of -21.7 kJ/mol with the SCS-MP2 method. Hydrocarbons 61-73 tryptase pseudogene 1 Homo sapiens 140-143 19319983-7 2009 Among men, the risk was increased in the highest exposure category of aromatic hydrocarbons [RR 1.77, 95% confidence interval (CI) 1.30-2.40], aliphatic/alicyclic hydrocarbons (RR 1.47, 95% CI 0.99-2.18), chlorinated hydrocarbons (RR 2.65, 95% CI 1.38-5.11) and "other solvents" (RR 2.14, 95% CI 1.23-3.71). Hydrocarbons 79-91 ribonucleotide reductase catalytic subunit M1 Homo sapiens 93-97 19319983-7 2009 Among men, the risk was increased in the highest exposure category of aromatic hydrocarbons [RR 1.77, 95% confidence interval (CI) 1.30-2.40], aliphatic/alicyclic hydrocarbons (RR 1.47, 95% CI 0.99-2.18), chlorinated hydrocarbons (RR 2.65, 95% CI 1.38-5.11) and "other solvents" (RR 2.14, 95% CI 1.23-3.71). Hydrocarbons 163-175 ribonucleotide reductase catalytic subunit M1 Homo sapiens 177-181 19319983-7 2009 Among men, the risk was increased in the highest exposure category of aromatic hydrocarbons [RR 1.77, 95% confidence interval (CI) 1.30-2.40], aliphatic/alicyclic hydrocarbons (RR 1.47, 95% CI 0.99-2.18), chlorinated hydrocarbons (RR 2.65, 95% CI 1.38-5.11) and "other solvents" (RR 2.14, 95% CI 1.23-3.71). Hydrocarbons 163-175 ribonucleotide reductase catalytic subunit M1 Homo sapiens 177-181 18706736-2 2009 Studies have linked the polymorphisms in N-acetyltransferases (NAT2), a key enzyme for metabolism of hydrocarbons, with lung cancer in Asian female nonsmokers. Hydrocarbons 101-113 N-acetyltransferase 2 Homo sapiens 63-67 19182999-3 2009 New definitions are introduced, and a consistent hierarchy of reaction classes (RC1-RC5) for hydrocarbons is constructed: isogyric (RC1) superset of isodesmic (RC2) superset of hypohomodesmotic (RC3) superset of homodesmotic (RC4) superset of hyperhomodesmotic (RC5). Hydrocarbons 93-105 chromobox 8 Homo sapiens 80-83 19673297-0 2009 Polarizability and spin density correlate with the relative anaerobic biodegradability of alkylaromatic hydrocarbons. Hydrocarbons 104-116 spindlin 1 Homo sapiens 19-23 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Hydrocarbons 105-117 Fad2 Drosophila melanogaster 50-62 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Hydrocarbons 105-117 Fad2 Drosophila melanogaster 157-169 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Hydrocarbons 105-117 Fad2 Drosophila melanogaster 157-169 18952610-2 2009 Recently, we showed that the CheB42a protein, which is expressed in only 10 pheromone-sensing taste hairs on the front legs of males, modulates progression to late stages of male courtship behavior in response to female-specific cuticular hydrocarbons. Hydrocarbons 239-251 Chemosensory protein B 42a Drosophila melanogaster 29-36 19054159-1 2009 Molecular analysis of the desaturase2 (desat2) gene responsible for female cuticular hydrocarbon synthesis, revealed that all tested Israeli populations of Drosophila melanogaster belong to the "Low" type (low ratio of 5,9-/7,11-heptacosadiene) with a 16 bp deletion in the promoter region. Hydrocarbons 85-96 Desaturase 2 Drosophila melanogaster 26-37 19054159-1 2009 Molecular analysis of the desaturase2 (desat2) gene responsible for female cuticular hydrocarbon synthesis, revealed that all tested Israeli populations of Drosophila melanogaster belong to the "Low" type (low ratio of 5,9-/7,11-heptacosadiene) with a 16 bp deletion in the promoter region. Hydrocarbons 85-96 Desaturase 2 Drosophila melanogaster 39-45 19167289-5 2009 Of significance, the conformations of the overlapping N- and C-terminal domains of apoA-I in the particles were unusually mobile, exposing hydrocarbon regions of the phospholipid to solvent; a lack of buried interhelical salt bridges in the terminal domains correlated with increased mobility. Hydrocarbons 139-150 apolipoprotein A1 Homo sapiens 83-89 19504513-0 2009 Tri-chain hydrocarbon surfactants as designed micellar modifiers for supercritical CO2. Hydrocarbons 10-21 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 0-3 19256400-0 2008 [Characterization of a thermophilic Geobacillus strain DM-2 degrading hydrocarbons]. Hydrocarbons 70-82 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 55-59 19256400-1 2008 A thermophilic Geobacillus strain DM-2 from a deep-subsurface oil reservoir was investigated on its capability of degrading crude oil under various conditions as well as its characters on degrading hydrocarbons in optimal conditions. Hydrocarbons 198-210 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 34-38 19256400-6 2008 Due to its characters of efficient emulsification, high-performance degradation of hydrocarbons and fatty-acid production under high temperature and anoxic condition, the strain DM-2 may be potentially applied to oil-waste treatment and microbial enhanced heavy oil recovery in extreme conditions. Hydrocarbons 83-95 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 178-182 18712874-4 2008 Purified bovine rhodopsin was reconstituted into a series of mono-unsaturated phosphatidylcholines with 14-20 carbons per hydrocarbon chain. Hydrocarbons 122-133 rhodopsin Bos taurus 16-25 18022761-1 2008 This paper intends to provide a glimpse of the within-the-fence activity of a major chlorine, caustic soda and chlorinated hydrocarbons manufacturing complex, immediately before and during the 2 weeks following Hurricane Rita. Hydrocarbons 123-135 RBPJ interacting and tubulin associated 1 Homo sapiens 221-225 18762189-2 2008 Ddc mutants and wild-type female flies treated with tyrosine hydroxylase inhibitors (alpha-methyltyrosine or 3-iodotyrosine) had fewer diene hydrocarbons (female pheromones) and there was a total (Ddc), partial (alpha-methyltyrosine) or no (3-iodotyrosine) rescue of hydrocarbon pattern after dopamine ingestion. Hydrocarbons 141-152 Dopa decarboxylase Drosophila melanogaster 0-3 18600471-1 2008 Unlike photosystem II (PSII) that catalyzes formation of the O-O bond, the cytochromes P450 (P450), members of a superfamily of hemoproteins, catalyze the scission of the O-O bond of dioxygen molecules and insert a single oxygen atom into unactivated hydrocarbons through a hydrogen abstraction-oxygen rebound mechanism. Hydrocarbons 251-263 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 87-91 18600471-1 2008 Unlike photosystem II (PSII) that catalyzes formation of the O-O bond, the cytochromes P450 (P450), members of a superfamily of hemoproteins, catalyze the scission of the O-O bond of dioxygen molecules and insert a single oxygen atom into unactivated hydrocarbons through a hydrogen abstraction-oxygen rebound mechanism. Hydrocarbons 251-263 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 93-97 18515395-12 2008 These observations suggest that cooperativity and/or conformational changes of the Abeta-oligomer particles upon transfer from the aqueous to the hydrocarbon environment play a prominent role in the interaction of the peptide with the membrane. Hydrocarbons 146-157 amyloid beta precursor protein Homo sapiens 83-88 18546721-14 2008 The tested PAHs accounted for < 1% of the total AHR-mediated response, indicating that considerable amounts of other aryl hydrocarbons must be present in filtered and unfiltered exhaust. Hydrocarbons 125-137 aryl hydrocarbon receptor Homo sapiens 51-54 18478171-0 2008 Hydrocarbon pollution in the sediment from the Jarzouna-Bizerte coastal area of Tunisia (Mediterranean Sea). Hydrocarbons 0-11 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 103-106 18076025-8 2008 The basic residues provide the driving force to orient PR3 at the membrane surface, so that the hydrophobic residues can anchor into the hydrocarbon region. Hydrocarbons 137-148 proteinase 3 Homo sapiens 55-58 18439024-8 2008 When it interacts with DPC, LL-37 is adsorbed on the surface of the micelle with the hydrophilic face exposed to the water phase and the hydrophobic face buried in the micelle hydrocarbon region. Hydrocarbons 176-187 cathelicidin antimicrobial peptide Homo sapiens 28-33 19206607-3 2008 A detailed mechanistic investigation leads us to conclude that the matching in nanorod concentration, intrinsic properties of CdS, and the hydrocarbon chains of the surfactants between adjacent CdS rods play key roles in the self-assembly. Hydrocarbons 139-150 CDP-diacylglycerol synthase 1 Homo sapiens 194-197 18504953-11 2008 In addition, the spatial transport and fate (i.e., air-sea exchange processes and water column diffusion) of the oil-related hydrocarbons in the sea surface were investigated. Hydrocarbons 125-137 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 145-148 18251511-1 2008 This study demonstrates that benzo[g]chrysene-11,12-dihydrodiol (B[g]C-11,12-dihydrodiol) derived from the fjord-region parent hydrocarbon B[g]C is oxidized by rat AKR1C9 with a k c a t/ K m 100 times greater than that observed with the commonly studied bay-region benzo[ a]pyrene-7,8-dihydrodiol (B[a]P-7,8-dihydrodiol). Hydrocarbons 127-138 aldo-keto reductase family 1, member C14 Rattus norvegicus 164-170 18207084-0 2008 Evolution of a desaturase involved in female pheromonal cuticular hydrocarbon biosynthesis and courtship behavior in Drosophila. Hydrocarbons 66-77 Desaturase 1 Drosophila melanogaster 15-25 18207084-11 2008 These differences could explain the functional polymorphism of desatF observed between both species, contributing to different cuticular hydrocarbon profiles, that constitute an effective barrier between species. Hydrocarbons 137-148 Fad2 Drosophila melanogaster 63-69 17662236-1 2007 The human, multifunctional peptide LL-37 causes membrane disruption by distinctly different mechanisms strongly dependent on the nature of the membrane lipid composition, varying not only with lipid headgroup charge but also with hydrocarbon chain length. Hydrocarbons 230-241 cathelicidin antimicrobial peptide Homo sapiens 35-40 18223655-4 2008 We highlight the pharmacologic relevance of phosphorylated BAD BH3 by using cell-permeable, hydrocarbon-stapled BAD BH3 helices that target glucokinase, restore glucose-driven mitochondrial respiration and correct the insulin secretory response in Bad-deficient islets. Hydrocarbons 92-103 glucokinase Homo sapiens 140-151 18223655-4 2008 We highlight the pharmacologic relevance of phosphorylated BAD BH3 by using cell-permeable, hydrocarbon-stapled BAD BH3 helices that target glucokinase, restore glucose-driven mitochondrial respiration and correct the insulin secretory response in Bad-deficient islets. Hydrocarbons 92-103 insulin Homo sapiens 218-225 17767946-5 2007 Removal of gas phase and a portion of the particle phase hydrocarbons with the denuder decreased the interleukin-8 (IL-8) secretion to unexposed levels. Hydrocarbons 57-69 C-X-C motif chemokine ligand 8 Homo sapiens 101-114 17767946-5 2007 Removal of gas phase and a portion of the particle phase hydrocarbons with the denuder decreased the interleukin-8 (IL-8) secretion to unexposed levels. Hydrocarbons 57-69 C-X-C motif chemokine ligand 8 Homo sapiens 116-120 17689549-2 2007 Using a 15-mer aptamer that binds thrombin primarily at the fibrinogen-recognition exosite as a model, we have demonstrated that introducing a DNA spacer in the aptamer enhances thrombin-binding capacity and stability, as similarly reported for hydrocarbon linkers. Hydrocarbons 245-256 coagulation factor II, thrombin Homo sapiens 34-42 17689549-2 2007 Using a 15-mer aptamer that binds thrombin primarily at the fibrinogen-recognition exosite as a model, we have demonstrated that introducing a DNA spacer in the aptamer enhances thrombin-binding capacity and stability, as similarly reported for hydrocarbon linkers. Hydrocarbons 245-256 coagulation factor II, thrombin Homo sapiens 178-186 17931665-0 2007 Distribution and origin of hydrocarbons in surficial sediments from the eastern Aegean Sea (Izmir Bay). Hydrocarbons 27-39 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 87-90 17662236-2 2007 Specifically, LL-37 induces a peptide-associated quasi-interdigitated phase in negatively charged phosphatidylglycerol (PG) model membranes, where the hydrocarbon chains are shielded from water by the peptide. Hydrocarbons 151-162 cathelicidin antimicrobial peptide Homo sapiens 14-19 17662236-5 2007 This dual behavior of LL-37 can be attributed to a balance between electrostatic interactions reflected in different penetration depths of the peptide and hydrocarbon chain length. Hydrocarbons 155-166 cathelicidin antimicrobial peptide Homo sapiens 22-27 17625862-0 2007 Gas-phase reactions of ClMn(H2O)+ with polar and nonpolar hydrocarbons in a mass spectrometer. Hydrocarbons 58-70 calmin Homo sapiens 23-27 17582468-6 2007 Serum from 44 Swedish men, occupationally exposed to halogenated hydrocarbons, was screened for antibodies against CYP2E1 with enzyme-linked immunosorbent assay. Hydrocarbons 65-77 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 115-121 17618724-1 2007 Aryl hydrocarbon receptor (AhR) plays important roles in the regulation and induction of xenobiotic-metabolizing enzymes including the cytochromes P450 1 family (CYP1) and UDP-glucuronosyltransferases 1A (UGT1As) by polycyclic aromatic hydrocarbons as well as chlorinated aromatic hydrocarbons. Hydrocarbons 236-248 aryl-hydrocarbon receptor Mus musculus 0-25 17618724-1 2007 Aryl hydrocarbon receptor (AhR) plays important roles in the regulation and induction of xenobiotic-metabolizing enzymes including the cytochromes P450 1 family (CYP1) and UDP-glucuronosyltransferases 1A (UGT1As) by polycyclic aromatic hydrocarbons as well as chlorinated aromatic hydrocarbons. Hydrocarbons 236-248 aryl-hydrocarbon receptor Mus musculus 27-30 17909020-5 2007 Furthermore, a carcinogenic dose of the parent hydrocarbon (BP) increased Cdc25B protein levels in the target organ, lung. Hydrocarbons 47-58 cell division cycle 25B Mus musculus 74-80 17258279-2 2007 The results indicated a significant contribution of tobacco smoke to the PAH contamination of milk: the condensate contained in the cigarettes smoked daily by each subject was strongly related with the polynuclear hydrocarbon content (R(2)=0.92, P<0.005). Hydrocarbons 214-225 phenylalanine hydroxylase Homo sapiens 73-76 17258237-0 2007 Hydrocarbons in coastal sediments from the Mediterranean sea (Gulf of Fos area, France). Hydrocarbons 0-12 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 57-60 17258237-5 2007 The origins of hydrocarbons are multiple: terrestrial inputs, biogenic, pyrolytic (industry emissions mainly steel and iron industries, ship and road traffic). Hydrocarbons 15-27 inositol polyphosphate-5-phosphatase D Homo sapiens 136-140 17489617-15 2007 Surfactants having the hydrophilic group bound to the C-2 or C-4 position or which contain a branched hydrocarbon tail are less efficient and exhibit in most cases visibly lower phase inversion temperatures. Hydrocarbons 102-113 complement C4A (Rodgers blood group) Homo sapiens 61-64 17425347-1 2007 In this paper we present a study of using oxygen plasma for chemically modifying inert hydrocarbon self-assembled monolayers of octadecyltrichlorosilane (OTS-SAMs) and rendering active surfaces for protein immobilization. Hydrocarbons 87-98 methionine adenosyltransferase 1A Homo sapiens 158-162 17395016-3 2007 We found that a prolonged exposure of alveolar macrophages to a nonlethal dose (8 microg/ml) of JP-8, the kerosene-based hydrocarbon jet fuel, induced the persistent expression of IL-1, iNOS, and COX-2, as well as cell adhesion molecules (ICAM-1 and VCAM-1). Hydrocarbons 121-132 interleukin 1 alpha Homo sapiens 180-184 17360514-0 2007 A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogaster. Hydrocarbons 58-69 elongase F Drosophila melanogaster 26-34 17360514-7 2007 Feminization of the hydrocarbon profile in males by using targeted expression of the transformer gene resulted in high expression levels of eloF, suggesting that the gene is under the control of the sex-determination hierarchy. Hydrocarbons 20-31 elongase F Drosophila melanogaster 140-144 16906435-15 2007 Hence, human exposure to PAH mixtures with high content of BaP-type hydrocarbons confers a potentially higher health risk than PAH mixtures with low content of procarcinogens. Hydrocarbons 68-80 prohibitin 2 Homo sapiens 59-62 17190491-6 2007 SANS data show that independently of the presence of polymer the radius of wormlike micelles is roughly equal to the length of a surfactant molecule, whereas the radius of spheres formed upon the absorption of hydrocarbon is 2-2.5-fold higher. Hydrocarbons 210-221 USH1 protein network component sans Homo sapiens 0-4 17012224-3 2007 Many AHR agonists, like the polyaromatic hydrocarbons and polyhalogenated hydrocarbons are known human carcinogens. Hydrocarbons 41-53 aryl hydrocarbon receptor Homo sapiens 5-8 17355550-0 2007 Striatal dopamine transporter binding in patients with Parkinson"s disease and severe occupational hydrocarbon exposure. Hydrocarbons 99-110 solute carrier family 6 member 3 Homo sapiens 9-29 17355550-1 2007 We used 123I-Ioflupane SPECT to study striatal dopamine transporter (DAT) binding in 36 Parkinson"s disease (PD) patients with history of severe occupational exposure to hydrocarbons. Hydrocarbons 170-182 solute carrier family 6 member 3 Homo sapiens 69-72 17724864-0 2007 Hydrocarbon toxicity: an analysis of AAPCC TESS data. Hydrocarbons 0-11 testin LIM domain protein Homo sapiens 43-47 17441143-2 2007 In hydrocarbon solvents, these polymers formed a physical gel and showed a thermoreversible spin transition upon the sol-gel phase transition. Hydrocarbons 3-14 spindlin 1 Homo sapiens 92-96 17441143-6 2007 Compared with nongelling references in aromatic solvents, the spin-crossover physical gels are characterized by their quick thermal response, which is due to a rapid restoration of the hydrogen-bonding network, possibly because of a dynamic structural ordering through an enhanced lipophilic interaction of the self-assembling components in hydrocarbon solvents. Hydrocarbons 341-352 spindlin 1 Homo sapiens 62-66 17591727-1 2007 The reactions of small saturated hydrocarbons by gaseous nickel cations NiX+ (X=F, Cl, Br, I) are investigated by means of electrospray ionization mass spectrometry. Hydrocarbons 33-45 BCL2 interacting protein 3 like Homo sapiens 72-75 17591727-7 2007 Additionally, inner-sphere electron-transfer reactions take place for a few systems, that is, the delivery of hydride or methanide ions from the hydrocarbon to NiX+ in the course of which the hydrocarbon is converted to a carbenium ion and the cationic metal complex gives rise to a neutral RNiX molecule (R=H, CH3). Hydrocarbons 145-156 BCL2 interacting protein 3 like Homo sapiens 160-163 17591727-7 2007 Additionally, inner-sphere electron-transfer reactions take place for a few systems, that is, the delivery of hydride or methanide ions from the hydrocarbon to NiX+ in the course of which the hydrocarbon is converted to a carbenium ion and the cationic metal complex gives rise to a neutral RNiX molecule (R=H, CH3). Hydrocarbons 192-203 BCL2 interacting protein 3 like Homo sapiens 160-163 16902966-3 2006 One example of this is the aryl hydrocarbon receptor (AHR), a basic-helix-loop-helix (bHLH)-Per-Arnt-Sim (PAS) transcription factor through which planar aromatic hydrocarbons cause altered gene expression and toxicity. Hydrocarbons 162-174 aryl hydrocarbon receptor Homo sapiens 27-52 17177408-1 2006 Anodic oxidation of the important half-sandwich compound CoCp(CO)2, 1, has been studied under gentle electrolyte conditions, e.g., chlorinated hydrocarbons with weakly coordinating anion (WCA) supporting electrolyte anions. Hydrocarbons 143-155 complement C2 Homo sapiens 57-69 16876970-4 2006 We also investigated PGM mRNA expression in oyster tissues in response to xenobiotics (i.e hydrocarbons and pesticides). Hydrocarbons 91-103 phosphoglucomutase Crassostrea gigas 21-24 16902966-3 2006 One example of this is the aryl hydrocarbon receptor (AHR), a basic-helix-loop-helix (bHLH)-Per-Arnt-Sim (PAS) transcription factor through which planar aromatic hydrocarbons cause altered gene expression and toxicity. Hydrocarbons 162-174 aryl hydrocarbon receptor Homo sapiens 54-57 16881636-3 2006 The other two products resulted from a highly unexpected migration of the hydrocarbon moiety to either dG5 or dG7 of the complementary strand, 5"-GGTAG5CG7ATGG-3". Hydrocarbons 74-85 g5 Drosophila melanogaster 103-106 16928110-0 2006 Rydberg fingerprint spectroscopy of hot molecules: structural dispersion in flexible hydrocarbons. Hydrocarbons 85-97 alcohol dehydrogenase iron containing 1 Homo sapiens 36-39 16881636-3 2006 The other two products resulted from a highly unexpected migration of the hydrocarbon moiety to either dG5 or dG7 of the complementary strand, 5"-GGTAG5CG7ATGG-3". Hydrocarbons 74-85 l(3)87Ee Drosophila melanogaster 110-113 16473566-7 2006 The ability of TLS polymerases to insert nucleotides opposite a hydrocarbon chain, despite the lack of any similarity to DNA, suggests that they may act via a mode of transient and local template-independent polymerase activity, and highlights the robustness of the TLS system in human cells. Hydrocarbons 64-75 FUS RNA binding protein Homo sapiens 15-18 16918316-3 2006 GSTT1-1 is highly conserved during evolution and plays a major role in phase-II biotransformation of a number of drugs and industrial chemicals, e.g. cytostatic drugs, hydrocarbons and halogenated hydrocarbons. Hydrocarbons 168-180 glutathione S-transferase theta 1 Homo sapiens 0-7 16787079-1 2006 A new hydrocarbon-soluble (additive-free) dicarbanionic organolithium initiator, obtained by a simple halogen-lithium exchange reaction (Gilman"s reaction) from a diarylhalide containing a side C15 alkyl chain, has been designed and used to initiate the anionic polymerization of butadiene and styrene. Hydrocarbons 6-17 placenta associated 8 Homo sapiens 194-197 16753571-4 2006 Here we show that CheB42a is expressed specifically in the sheath cells surrounding the taste neurons expressing Gr68a, a putative gustatory pheromone receptor for female cuticular hydrocarbons that stimulate male courtship. Hydrocarbons 181-193 Chemosensory protein B 42a Drosophila melanogaster 18-25 16753571-4 2006 Here we show that CheB42a is expressed specifically in the sheath cells surrounding the taste neurons expressing Gr68a, a putative gustatory pheromone receptor for female cuticular hydrocarbons that stimulate male courtship. Hydrocarbons 181-193 Gustatory receptor 68a Drosophila melanogaster 113-118 16753571-6 2006 Furthermore, CheB42a mutant males also attempt to copulate more frequently with other males that secrete female-specific cuticular hydrocarbon pheromones, but not with females lacking cuticular hydrocarbons. Hydrocarbons 131-142 Chemosensory protein B 42a Drosophila melanogaster 13-20 16753571-6 2006 Furthermore, CheB42a mutant males also attempt to copulate more frequently with other males that secrete female-specific cuticular hydrocarbon pheromones, but not with females lacking cuticular hydrocarbons. Hydrocarbons 194-206 Chemosensory protein B 42a Drosophila melanogaster 13-20 16741777-2 2006 The method uses near-infrared (NIR) transmission spectra obtained from leachates of the hydrocarbons with CCl4 using a partial least-squares (PLS) calibration model based on the use of mixtures of n-hexane, isooctane, and toluene diluted with CCl4. Hydrocarbons 88-100 C-C motif chemokine ligand 4 Homo sapiens 106-110 16491495-0 2006 Hexa- and octacoordinate carbon in hydrocarbon cages: theoretical design and characterization. Hydrocarbons 35-46 hexosaminidase subunit alpha Homo sapiens 0-4 16491495-1 2006 A new series of hydrocarbon cages containing hexa- and octacoordinate carbon centers were designed theoretically by performing DFT calculations at the B3 LYP/6-311+G** level. Hydrocarbons 16-27 hexosaminidase subunit alpha Homo sapiens 45-49 16491495-1 2006 A new series of hydrocarbon cages containing hexa- and octacoordinate carbon centers were designed theoretically by performing DFT calculations at the B3 LYP/6-311+G** level. Hydrocarbons 16-27 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 154-157 16918316-3 2006 GSTT1-1 is highly conserved during evolution and plays a major role in phase-II biotransformation of a number of drugs and industrial chemicals, e.g. cytostatic drugs, hydrocarbons and halogenated hydrocarbons. Hydrocarbons 197-209 glutathione S-transferase theta 1 Homo sapiens 0-7 16907833-5 2006 When hydrocarbons were feminized in D. melanogaster males by targeted expression of the transformer gene, the expression of desatF occurred. Hydrocarbons 5-17 transformer Drosophila melanogaster 88-99 16907833-5 2006 When hydrocarbons were feminized in D. melanogaster males by targeted expression of the transformer gene, the expression of desatF occurred. Hydrocarbons 5-17 Fad2 Drosophila melanogaster 124-130 16863231-5 2006 It is shown that in surfactant mixtures containing SDS the maximal repulsive force (the barrier F(bar)) at which the tip punctured the micelles, as well as the magnitudes of E and Y, attained the maximal values for C(12)TAB ( i.e., when the hydrocarbon chain lengths of two oppositely charged surfactants are the same). Hydrocarbons 241-252 TOR signaling pathway regulator Homo sapiens 117-120 16771408-0 2006 Regarding the effect that different hydrocarbon/fluorocarbon surfactant mixtures have on their complexation with HSA. Hydrocarbons 36-47 albumin Homo sapiens 113-116 16737272-1 2006 A molecular mechanics study of small saturated hydrocarbons (up to C-6) substituted by up to six fluorines has been carried out with the MM4 force field. Hydrocarbons 47-59 complement C6 Homo sapiens 67-70 16779580-17 2006 A viscous hydrocarbon paste uncovered in API 1 was insoluble in water but dissolved in dichloromethane. Hydrocarbons 10-21 baculoviral IAP repeat containing 2 Homo sapiens 41-46 16473566-7 2006 The ability of TLS polymerases to insert nucleotides opposite a hydrocarbon chain, despite the lack of any similarity to DNA, suggests that they may act via a mode of transient and local template-independent polymerase activity, and highlights the robustness of the TLS system in human cells. Hydrocarbons 64-75 FUS RNA binding protein Homo sapiens 266-269 16412504-9 2006 PMCA associates much more strongly with phosphatidylcholine containing disordered hydrocarbon chains than ordered hydrocarbon chains. Hydrocarbons 82-93 ATPase plasma membrane Ca2+ transporting 2 Homo sapiens 0-4 16491497-2 2006 The water-soluble PEG-supported ruthenium porphyrin (PEG-1) is an efficient catalyst for 2,6-Cl(2)pyNO oxidation and PhI==NTs aziridination/amidation of hydrocarbons, and intramolecular amidation of sulfamate esters with PhI(OAc)(2). Hydrocarbons 153-165 mesoderm specific transcript Homo sapiens 53-58 17193279-3 2006 Soil physicochemical properties such as pH, moisture content, heavy metal, TOC, and TOM, all provided corroborative evidence of hydrocarbon attenuation. Hydrocarbons 128-139 pre-mRNA processing factor 6 Homo sapiens 84-87 15935450-6 2006 The transformations observed showed that water weathering leads to more effective and rapid elimination of low molecular weight hydrocarbons than microbial mat metabolism, e.g. n-alkanes with chain length shorter than n-pentadecane or n-heptadecane, regular isoprenoid hydrocarbons with chain length lower than C16 or C18 or lower molecular weight naphthalenes. Hydrocarbons 128-140 Bardet-Biedl syndrome 9 Homo sapiens 318-321 16491497-3 2006 Oxidation of PEG-1 by m-CPBA in CH(2)Cl(2), dioxane, or water afforded a water-soluble PEG-supported dioxoruthenium(VI) porphyrin (PEG-2), which could react with hydrocarbons to give oxidation products in up to 80 % yield. Hydrocarbons 162-174 mesoderm specific transcript Homo sapiens 13-18 16412504-9 2006 PMCA associates much more strongly with phosphatidylcholine containing disordered hydrocarbon chains than ordered hydrocarbon chains. Hydrocarbons 114-125 ATPase plasma membrane Ca2+ transporting 2 Homo sapiens 0-4 16204508-13 2005 This and the presence of an alkB gene homolog in this isolate confirmed the alkane degradation capability of one population indigenous to acidic hydrocarbon seep soils. Hydrocarbons 145-156 alkB homolog 1, histone H2A dioxygenase Homo sapiens 28-32 16365868-6 2006 This suggests that C2F is a reactive radical like the extensively studied C2H, in contrast to the situation of the CF and CF2 radicals that have much lower reactivity than the corresponding hydrocarbon species. Hydrocarbons 190-201 EMG1 N1-specific pseudouridine methyltransferase Homo sapiens 19-22 16482161-2 2006 Escherichia coli AlkB and the homologous human proteins ABH2 and ABH3 (refs 5, 7) promiscuously repair DNA and RNA bases damaged by S(N)2 alkylation reagents, which attach hydrocarbons to endocyclic ring nitrogen atoms (N1 of adenine and guanine and N3 of thymine and cytosine). Hydrocarbons 172-184 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Homo sapiens 56-60 16482161-2 2006 Escherichia coli AlkB and the homologous human proteins ABH2 and ABH3 (refs 5, 7) promiscuously repair DNA and RNA bases damaged by S(N)2 alkylation reagents, which attach hydrocarbons to endocyclic ring nitrogen atoms (N1 of adenine and guanine and N3 of thymine and cytosine). Hydrocarbons 172-184 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase Homo sapiens 65-69 16251509-2 2006 ds2 is responsible for a cuticular hydrocarbon difference between two behaviorally isolated races--Zimbabwe (Z) and Cosmopolitan (M). Hydrocarbons 35-46 Desaturase 2 Drosophila melanogaster 0-3 16401082-0 2006 Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes. Hydrocarbons 52-64 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 88-103 16853878-2 2005 We revealed that the negative charge carrier transport in its smectic mesophases had two different mechanisms, i.e., electronic and ionic conductions: we observed two transits of the carriers in both the smectic A (SmA) and smectic B (SmB) phases and demonstrated their origins by dilution experiments with a hydrocarbon (n-dodecane); the fast transit was attributed to the electronic transport of electrons and the slow one to the ionic transport of negative ions. Hydrocarbons 309-320 survival of motor neuron 1, telomeric Homo sapiens 215-218 15961122-0 2005 Hydrocarbons in surface sediments from the Sfax coastal zone, (Tunisia) Mediterranean Sea. Hydrocarbons 0-12 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 86-89 16277336-0 2005 G3(MP2) ring strain in bicyclic phosphorus heterocycles and their hydrocarbon analogues. Hydrocarbons 66-77 tryptase pseudogene 1 Homo sapiens 3-6 15967578-6 2005 This observation demonstrates that part of factor Xa can cross the phospholipid polar headgroup/hydrocarbon chain interface. Hydrocarbons 96-107 coagulation factor X Homo sapiens 43-52 16197231-2 2005 Our results show that a sp2 bonded cap is formed on an iron catalyst, following the diffusion of C atoms from hydrocarbon precursors on the nanoparticle surface. Hydrocarbons 110-121 Sp2 transcription factor Homo sapiens 24-27 15908585-4 2005 However, previous detergent extraction experiments with bilayers containing raft and nonraft domains have shown that the peptides P-23 and P-29, designed to have single TMDs matching the hydrocarbon thicknesses of detergent soluble membranes and detergent resistant membranes, respectively, are both localized to detergent soluble membranes. Hydrocarbons 187-198 prostaglandin E synthase 3 Homo sapiens 130-134 15908585-4 2005 However, previous detergent extraction experiments with bilayers containing raft and nonraft domains have shown that the peptides P-23 and P-29, designed to have single TMDs matching the hydrocarbon thicknesses of detergent soluble membranes and detergent resistant membranes, respectively, are both localized to detergent soluble membranes. Hydrocarbons 187-198 SYF2 pre-mRNA splicing factor Homo sapiens 139-143 15962049-2 2005 1 adopts an open structure similar to that of the isoelectronic hydrocarbon molecule permethylbutadiene; the central B-N bond distance at 148.0/149.3(7) pm (MP2/GED) corresponds to a single covalent N--B bond distance, the two terminal distances, 140.9/140.5(4) pm and 141.8/141.3(4) pm, correspond to the distance between N and B atoms joined by a covalent sigma-bond and a dative pi-bond. Hydrocarbons 64-75 tryptase pseudogene 1 Homo sapiens 157-160 15922868-5 2005 These hydrocarbons also stimulated MMP-9 protein secretion. Hydrocarbons 6-18 matrix metallopeptidase 9 Homo sapiens 35-40 15944086-1 2005 In Drosophila melanogaster, desat1 is involved in the synthesis of fatty acids (FAs), some of which are precursors in the production of unsaturated hydrocarbons (HCs) in position 7 (7-HC) that play an important role in mating behaviour. Hydrocarbons 162-165 Desaturase 1 Drosophila melanogaster 28-34 16852444-2 2005 In the revised model (ISM-2), the interactions between the hydrophobic sites of the surfactants are varied depending on their surroundings, namely, the local hydrocarbon density. Hydrocarbons 158-169 isthmin 2 Homo sapiens 22-27 16240586-1 2005 Nanoparticles of organic carbon (NOC) are formed in combustion of hydrocarbon-rich fuels and have been detected in vehicle exhausts, suggesting their presence in urban atmospheres. Hydrocarbons 66-77 nocturnin Homo sapiens 33-36 16852444-4 2005 As a result, it was found that the ISM-2 can mimic the n-hexane/water interface and represent the fluidity of the hydrocarbon interior of the surfactant micelle that the original ISM fails to do. Hydrocarbons 114-125 isthmin 2 Homo sapiens 35-40 15683365-4 2005 Human GST T1-1 activity is considerably lower with halogenated hydrocarbons and some related substrates. Hydrocarbons 63-75 CD2 molecule Homo sapiens 10-14 15924998-13 2005 Biophysical studies in both model membranes and in native membranes have demonstrated that cholesterol can modulate the activity of rhodopsin by altering the membrane hydrocarbon environment. Hydrocarbons 167-178 rhodopsin Homo sapiens 132-141 15787527-1 2005 An overview of the research of the Olah group over five decades--ranging from synthetic reagents and methods to mechanistic-structural studies to new hydrocarbon chemistry and the development of methanol based fuels and hydrocarbon synthesis--is presented. Hydrocarbons 150-161 oleoyl-ACP hydrolase Homo sapiens 35-39 15787527-1 2005 An overview of the research of the Olah group over five decades--ranging from synthetic reagents and methods to mechanistic-structural studies to new hydrocarbon chemistry and the development of methanol based fuels and hydrocarbon synthesis--is presented. Hydrocarbons 220-231 oleoyl-ACP hydrolase Homo sapiens 35-39 15752461-3 2005 This single transition splits into two transitions for C18, and FTIR shows that the upper main transition is predominantly the melting of the hydrocarbon chains whereas the lower transition involves changes in the headgroup ordering as well as changes in the lateral packing of the chains. Hydrocarbons 142-153 Bardet-Biedl syndrome 9 Homo sapiens 55-58 15565726-1 2005 The bow-shaped molecule 1 bearing a self-complementary DAAD-ADDA (D=donor A=acceptor) hydrogen-bonding array generates, in hydrocarbon solvents, highly ordered supramolecular sheet aggregates that subsequently give rise to gels by formation of an entangled network. Hydrocarbons 123-134 adducin 1 Homo sapiens 60-64 15653316-4 2005 The atomic structures of CD1-antigen complexes have defined both the orientation of polar headgroups between the alpha1 and alpha2 helices of CD1 and the manner in which distinct CD1 isoforms bind a range of lipids that have different lengths and numbers of hydrocarbon chains. Hydrocarbons 258-269 CD1c molecule Homo sapiens 25-28 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Hydrocarbons 194-206 epoxide hydrolase 1 Homo sapiens 6-34 15551059-2 2005 Here we present the first complete genome of a metabolically versatile representative, strain EbN1, which metabolizes various aromatic compounds, including hydrocarbons. Hydrocarbons 156-168 potassium voltage-gated channel subfamily Q member 2 Homo sapiens 94-98 16161783-5 2005 In addition, the reaction of hydrocarbons with NO3 potentially has important implications for NOy speciation because a significant fraction of organic nitrates thus formed are sufficiently long-lived to leave the planetary boundary layer. Hydrocarbons 29-41 NBL1, DAN family BMP antagonist Homo sapiens 47-50 15535985-1 2004 Human microsomal epoxide hydrolase (EPHX1) is active in the metabolism of many potentially carcinogenic or otherwise genotoxic epoxides, such as those derived from the oxidation of polyaromatic hydrocarbons. Hydrocarbons 194-206 epoxide hydrolase 1 Homo sapiens 36-41 15534505-6 2004 CONCLUSIONS: The higher prevalence of respiratory symptoms in Kerinci and SP7 could be the result of higher PM10 and hydrocarbon levels in these locations. Hydrocarbons 117-128 Sp7 transcription factor Homo sapiens 74-77 15560776-2 2004 Cytochrome P450 enzymes promote a number of oxidative biotransformations including the hydroxylation of unactivated hydrocarbons. Hydrocarbons 116-128 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 15380436-5 2004 For NaOl/CnG mixed systems, a decrease in the hydrocarbon chain length of CnG resulted in a stronger interaction with NaOl from both beta and B1 values. Hydrocarbons 46-57 immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens 133-144 15491223-10 2004 The result of our experiment clearly showed that, in addition to electrostatic interaction, van der Waals interaction generating between the hydrophobic long-chain hydrocarbons of the adsorption film and the surfactant improved significantly the adsorption stability of the SnO(x) colloids, resulting in highly selective Ni-deposition in accord with the photopattern shape of the cationic single-layer adsorption film. Hydrocarbons 164-176 strawberry notch homolog 1 Homo sapiens 274-277 15245914-7 2004 It was also clearly demonstrated that the transcription levels of MAO A (generally considered a constitutive enzyme without external regulation) were induced by hydrocarbons and pesticides in digestive gland and inhibited by pesticides in gill tissue. Hydrocarbons 161-173 amine oxidase [flavin-containing] A Crassostrea gigas 66-71 15691019-1 2004 We reported previously that unsaturated linear-chain FA of the cis-configuration with a C18-hydrocarbon chain such as linoleic acid (18:2delta9c,12c) could potently inhibit the activities of mammalian DNA polymerases and DNA topoisomerases, but their saturated forms could not. Hydrocarbons 92-103 Bardet-Biedl syndrome 9 Homo sapiens 88-91 15351271-2 2004 Phospholipid derivatives, spin labeled at the 5th and 16th C-atoms along the hydrocarbon chain, incorporated in diC(14)-amidine bilayers, show that the bilayer structure is highly sensitive to the pH value of the medium, due to the two titratable groups present in the amphiphile. Hydrocarbons 77-88 spindlin 1 Homo sapiens 26-30 15323515-0 2004 Elucidation of the pore structure of SBA-2 using Monte Carlo simulation to interpret experimental data for the adsorption of light hydrocarbons. Hydrocarbons 131-143 WD repeat and SOCS box containing 2 Homo sapiens 37-42 15245914-8 2004 Furthermore, the transcription levels of FMO-2 and MAO A mRNA in digestive gland might be useful as a marker of hydrocarbon or pesticide exposure in monitoring programs. Hydrocarbons 112-123 dimethylaniline monooxygenase [N-oxide-forming] 2-like Crassostrea gigas 41-46 15475306-5 2004 In addition to these elements, the CYP6B4 and CYP6B1 promoters also contain putative XRE-AhR elements identical to the aryl hydrocarbon response elements present in mammalian phase I detoxification genes. Hydrocarbons 124-135 aryl hydrocarbon receptor Homo sapiens 89-92 15327162-0 2004 Determination of hydrocarbons in mussels from the Egyptian Red Sea coast. Hydrocarbons 17-29 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 63-66 15245914-8 2004 Furthermore, the transcription levels of FMO-2 and MAO A mRNA in digestive gland might be useful as a marker of hydrocarbon or pesticide exposure in monitoring programs. Hydrocarbons 112-123 amine oxidase [flavin-containing] A Crassostrea gigas 51-56 15223354-10 2004 As with the parent hydrocarbon, mice treated with low doses of diastereomeric syn- and anti-dihydrodiol epoxides of DBP showed increased tumor incidences in liver (incidence: 19.0 and 46.7%; yield: 0.36 and 1.47 tumors per mouse, respectively), and in various other organs (incidence: 7.1 and 20.0%; yield: 0.07 and 0.20 tumors per mouse, respectively). Hydrocarbons 19-30 joined toes Mus musculus 78-81 15223354-10 2004 As with the parent hydrocarbon, mice treated with low doses of diastereomeric syn- and anti-dihydrodiol epoxides of DBP showed increased tumor incidences in liver (incidence: 19.0 and 46.7%; yield: 0.36 and 1.47 tumors per mouse, respectively), and in various other organs (incidence: 7.1 and 20.0%; yield: 0.07 and 0.20 tumors per mouse, respectively). Hydrocarbons 19-30 D site albumin promoter binding protein Mus musculus 116-119 15984265-3 2004 The degree of surface heterogeneity at the SAMs increases as the number of C units (n) in the hydrocarbon chain decreases from n = 6. Hydrocarbons 94-105 methionine adenosyltransferase 1A Homo sapiens 43-47 14744814-6 2004 The lipid with 18 hydrocarbons modestly increased I(HERG). Hydrocarbons 18-30 potassium voltage-gated channel subfamily H member 2 Homo sapiens 52-56 14971482-5 2004 Flash heating of the sorbent trap desorbed the enriched VOCs onto the gas chromatography (GC) with flame ionization detection (FID) for hydrocarbons or electron-capture detection (ECD) for halocarbons. Hydrocarbons 136-148 TRAP Homo sapiens 29-33 15194169-5 2004 Induction of these autoantibodies appeared to be associated with the hydrocarbon"s ability to induce IL-12, IL-6, and TNF-alpha, suggesting a relationship with hydrocarbon"s adjuvanticity. Hydrocarbons 69-80 interleukin 6 Homo sapiens 108-112 15194169-5 2004 Induction of these autoantibodies appeared to be associated with the hydrocarbon"s ability to induce IL-12, IL-6, and TNF-alpha, suggesting a relationship with hydrocarbon"s adjuvanticity. Hydrocarbons 69-80 tumor necrosis factor Homo sapiens 118-127 15194169-5 2004 Induction of these autoantibodies appeared to be associated with the hydrocarbon"s ability to induce IL-12, IL-6, and TNF-alpha, suggesting a relationship with hydrocarbon"s adjuvanticity. Hydrocarbons 160-171 tumor necrosis factor Homo sapiens 118-127 15116219-1 2004 A series of cobalt-free and low cost perovskite oxygen permeable membranes based on BaCe(x)Fe(1-x)O(3-delta)(BCF) oxides was successfully synthesized and the membrane showed both high oxygen permeability and high stability under reductive atmosphere, which will be most suitable for constructing a membrane reactor for selective oxidation of light hydrocarbons to syngas or high value corresponding oxygenates. Hydrocarbons 348-360 beta-secretase 1 Homo sapiens 84-88 15058961-0 2004 Lithiated hydrocarbons, their conjugate bases, and corresponding radicals: a computational study of RLi (R = CH3, CH3CH2, CH2=CH, and HC triple bond C). Hydrocarbons 10-22 ATP binding cassette subfamily E member 1 Homo sapiens 100-103 14744814-14 2004 We conclude that enhancement of HERG function by lysophospholipids is specific to the lipids with 16-hydrocarbon chain structure and the pattern of voltage dependence is determined by the polar headgroups. Hydrocarbons 101-112 potassium voltage-gated channel subfamily H member 2 Homo sapiens 32-36 14720319-7 2004 Significantly, gene expression of CYP1A1 and 1B1 is induced by PAHs and polyhalogenated hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin through the arylhydrocarbon receptor. Hydrocarbons 88-100 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 34-48 14659860-4 2003 We propose using hydrocarbon polymer-coated stents immersed in VEGF to speed re-endothelialisation and reduce the risk of stent thrombosis and restenosis. Hydrocarbons 17-28 vascular endothelial growth factor A Homo sapiens 63-67 14709624-8 2004 We conclude that CYP1As and FMO3 are the major phase I enzymes involved in the metabolism of S 16020 and that this molecule is a potent hydrocarbon-like inducer able to stimulate its own metabolism in primary human hepatocytes and liver. Hydrocarbons 136-147 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 17-21 15137640-1 2004 Carbon nanotubes prepared by catalytic chemical vapor deposition of hydrocarbon at 650 degrees C show good adsorption capability of Pb2+, Cu2+ and Cd2+ ions from aqueous solution after oxidized with concentrated nitric acid at 140 degrees C for 1 h. The specific surface area and particle size distribution of the as-grown and oxidized CNTs were studied by BET method and laser particle analyzer. Hydrocarbons 68-79 CD2 molecule Homo sapiens 147-150 15137640-1 2004 Carbon nanotubes prepared by catalytic chemical vapor deposition of hydrocarbon at 650 degrees C show good adsorption capability of Pb2+, Cu2+ and Cd2+ ions from aqueous solution after oxidized with concentrated nitric acid at 140 degrees C for 1 h. The specific surface area and particle size distribution of the as-grown and oxidized CNTs were studied by BET method and laser particle analyzer. Hydrocarbons 68-79 delta/notch like EGF repeat containing Homo sapiens 357-360 15244335-7 2004 Hydrocarbon composition in the soil contaminated with 140,000 mg TPHs/Kg soil, consisted in 80% of branched aliphatic compounds of C10 to C22, 15% of alkyl PAHs, and 5% of PAS compounds. Hydrocarbons 0-11 homeobox C10 Homo sapiens 131-134 12944280-6 2003 P-23 and P-29 were designed to have transbilayer domains that matched the hydrocarbon thicknesses of DSMs and DRMs, respectively. Hydrocarbons 74-85 prostaglandin E synthase 3 Homo sapiens 0-4 14652185-5 2003 Contour velocity plots for inelastic scattering of CD5+ from hydrocarbon-coated and hydrocarbon-free highly oriented pyrolytic graphite (HOPG) surfaces gave effective masses of the surface involved in the scattering event, approximately matching that of an ethyl group (or two methyl groups) and four to five carbon atoms, respectively. Hydrocarbons 61-72 CD5 molecule Homo sapiens 51-54 14507707-4 2003 Two sets of data indicate that the phenylalanine residues of the MARCKS-ED are positioned within the membrane hydrocarbon a few angstroms from the aqueous-hydrocarbon interface. Hydrocarbons 110-121 myristoylated alanine rich protein kinase C substrate Homo sapiens 65-71 14507707-4 2003 Two sets of data indicate that the phenylalanine residues of the MARCKS-ED are positioned within the membrane hydrocarbon a few angstroms from the aqueous-hydrocarbon interface. Hydrocarbons 155-166 myristoylated alanine rich protein kinase C substrate Homo sapiens 65-71 14507707-8 2003 These results indicate that highly charged peptides such as the MARCKS-ED penetrate the membrane interface with aromatic amino acid side chains inserted into the hydrocarbon and the peptide backbone lying within the bilayer interface. Hydrocarbons 162-173 myristoylated alanine rich protein kinase C substrate Homo sapiens 64-70 13129379-7 2003 We also note that for simple hydrocarbons which give localized carbanions upon deprotonation there is an apparent linear correlation between any two of the following three quantities: deltaH degrees (acid), BDE, and EA. Hydrocarbons 29-41 homeobox D13 Homo sapiens 207-210 12972062-1 2003 Aryl hydrocarbons such as dioxins, polychlorinated biphenyls and polyaromatic hydrocarbons bind to the cellular aryl hydrocarbon receptor (AhR) in the initial step of their metabolism. Hydrocarbons 5-17 aryl-hydrocarbon receptor Mus musculus 112-137 12972062-1 2003 Aryl hydrocarbons such as dioxins, polychlorinated biphenyls and polyaromatic hydrocarbons bind to the cellular aryl hydrocarbon receptor (AhR) in the initial step of their metabolism. Hydrocarbons 5-17 aryl hydrocarbon receptor Homo sapiens 139-142 14580712-6 2003 When the hydrocarbon chains were attached to the PEG chain via an ether or an ester the leakage increased compared to pure EPC liposomes. Hydrocarbons 9-20 progestagen associated endometrial protein Homo sapiens 49-52 12944280-6 2003 P-23 and P-29 were designed to have transbilayer domains that matched the hydrocarbon thicknesses of DSMs and DRMs, respectively. Hydrocarbons 74-85 SYF2 pre-mRNA splicing factor Homo sapiens 9-13 12732685-11 2003 CONCLUSION: These studies showed that radiometallated DOTA-X-BBN[7-14]NH(2) constructs with hydrocarbon spacers ranging from 5 to 8 carbon atoms are feasible candidates for further development as diagnostic and therapeutic radiopharmaceuticals for patients with GRP-positive cancers. Hydrocarbons 92-103 gastrin releasing peptide Homo sapiens 61-64 14574628-7 2003 Membrane acyl-chains in the hydrocarbon core are most susceptible to Abeta. Hydrocarbons 28-39 amyloid beta precursor protein Homo sapiens 69-74 12697024-13 2003 Phosphorylation of GNMT would thus seem to play no role in regulation of the intracellular AdoMet/AdoHcy ratio, but could be involved in other GNMT functions, such as the binding of folates or aromatic hydrocarbons. Hydrocarbons 202-214 glycine N-methyltransferase Rattus norvegicus 19-23 12739654-1 2003 Microporous hexagonal niobium phosphate synthesized using neutral surfactants of molecular length, C6 to C10 hydrocarbons, by a supramolecular templating mechanism (S0I0) possesses strong hydrophilic character, which leads to high selectivity for catechol formation (95.3%) in the presence of protic solvent (MeOH) in the hydroxylation of phenol using aqueous H2O2. Hydrocarbons 109-121 homeobox C10 Homo sapiens 105-108 12687018-4 2003 Treatment with 3 microM BaP, a hydrocarbon ligand of Ahr, inhibited glomerulogenesis and branching morphogenesis of metanephric kidneys. Hydrocarbons 31-42 aryl-hydrocarbon receptor Mus musculus 53-56 12687018-6 2003 Hydrocarbon treatment markedly induced -KTS wt1 splice variants, although total wt1 mRNA levels remained unchanged. Hydrocarbons 0-11 WT1 transcription factor Mus musculus 44-47 12558168-8 2003 Expression of CYP1A1 and vitellogenin in trout at both streams indicated that exposure to bioavailable hydrocarbons and endocrine-disrupting compounds had taken place. Hydrocarbons 103-115 LOC100136735 Oncorhynchus mykiss 25-37 12887098-2 2003 Previous work from these laboratories has demonstrated that administration of aerosolized substance P (SP) was capable of protecting the pulmonary and immune systems from damage due to environmental toxicants (e.g. hydrocarbon exposures). Hydrocarbons 215-226 tachykinin 1 Mus musculus 90-101 12887098-2 2003 Previous work from these laboratories has demonstrated that administration of aerosolized substance P (SP) was capable of protecting the pulmonary and immune systems from damage due to environmental toxicants (e.g. hydrocarbon exposures). Hydrocarbons 215-226 tachykinin 1 Mus musculus 103-105 12668448-5 2003 The thickness of the hydrocarbon chain region, determined by the tilt of the hydrocarbon chains and transmembrane domain with respect to the monolayer plane, was slightly different for Tm, TmCy, and Vpu systematically with protein/lipid mole ratio. Hydrocarbons 21-32 Vpu Human immunodeficiency virus 1 199-202 12668448-5 2003 The thickness of the hydrocarbon chain region, determined by the tilt of the hydrocarbon chains and transmembrane domain with respect to the monolayer plane, was slightly different for Tm, TmCy, and Vpu systematically with protein/lipid mole ratio. Hydrocarbons 77-88 Vpu Human immunodeficiency virus 1 199-202 12668448-7 2003 Thus, the interaction of the cytoplasmic domain of Vpu on the surface may affect the tilt of the transmembrane helix within the hydrocarbon chain region in determining its tertiary structure in the membrane. Hydrocarbons 128-139 Vpu Human immunodeficiency virus 1 51-54 12690492-1 2003 The importance of the isoform CYP2E1 of the human cytochrome P-450 superfamily of enzymes for occupational and environmental medicine is derived from its unique substrate spectrum that includes a number of highly important high-production chemicals, such as aliphatic and aromatic hydrocarbons, solvents and industrial monomers (i.a. Hydrocarbons 281-293 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 30-36 12515543-10 2003 (2002) Biochemistry 41, 6282), a similar orientation for the beta-sandwich region is found; however, the cPLA2 C2 domain is translocated 5-7 A deeper into the membrane hydrocarbon. Hydrocarbons 168-179 phospholipase A2 group IVA Homo sapiens 105-110 12559581-1 2003 The aryl hydrocarbon receptor (AhR) mediates the toxicity of several environmental contaminants, e.g. 2,3,7,8-tetrachlorodibenzo-p-dioxin, and other halogenated hydrocarbons in vertebrates. Hydrocarbons 161-173 aryl hydrocarbon receptor Salmo salar 4-29 12559581-1 2003 The aryl hydrocarbon receptor (AhR) mediates the toxicity of several environmental contaminants, e.g. 2,3,7,8-tetrachlorodibenzo-p-dioxin, and other halogenated hydrocarbons in vertebrates. Hydrocarbons 161-173 aryl hydrocarbon receptor Salmo salar 31-34 12909734-10 2003 A number of environmental and lifestyle factors, such as smoking, alcohol, coffee consumption, and exposure to organochlorine or hydrocarbon solvent, have been associated with the frequency and spectrum of K-ras mutation in pancreatic tumors. Hydrocarbons 129-140 KRAS proto-oncogene, GTPase Homo sapiens 206-211 12561335-1 2002 The scale of production-destruction biotic balance in the Black Sea ecosystem, flows of organic carbon, carbon dioxide, and oxygen, and rate and volume of organic matter input in the Black Sea sediment as a source of formation and accumulation of fossilized hydrocarbon fuel minerals are estimated on the basis of the current concept of efficiency of solar radiation utilization by photosynthesis. Hydrocarbons 258-269 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 64-67 12516021-1 2002 Tetrachloroethylene -- also known as Perchloroethylene, PCE and perc -- is a chlorinated hydrocarbon with the formula C2 Cl4, which is widely used as a degreasing solvent in drycleaning. Hydrocarbons 89-100 PPARG coactivator 1 beta Homo sapiens 64-68 12561335-1 2002 The scale of production-destruction biotic balance in the Black Sea ecosystem, flows of organic carbon, carbon dioxide, and oxygen, and rate and volume of organic matter input in the Black Sea sediment as a source of formation and accumulation of fossilized hydrocarbon fuel minerals are estimated on the basis of the current concept of efficiency of solar radiation utilization by photosynthesis. Hydrocarbons 258-269 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 189-192 12364551-2 2002 In this analog, which was orginally designed to inhibit verotoxin binding to its glycolipid receptor, Gb(3), the fatty acid chain is replaced with a rigid globular hydrocarbon frame (adamantane). Hydrocarbons 164-175 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 102-107 12092812-2 2002 These hydrocarbons are the characteristic components of the cuticular hydrocarbons of the queen of the ant, Diacamma sp.. Hydrocarbons 6-18 solute carrier family 25 member 6 Homo sapiens 103-106 12204825-7 2002 Another of the HDI-increased genes, a dihydrodiol dehydrogenase, encodes a protein previously shown to be specifically susceptible to HDI conjugation, and known to detoxify other hydrocarbons. Hydrocarbons 179-191 dihydrodiol dehydrogenase Homo sapiens 38-63 12215678-7 2002 There were differences between the aliphatic hydrocarbons with respect to their effects on IL-8 release. Hydrocarbons 45-57 C-X-C motif chemokine ligand 8 Homo sapiens 91-95 12215678-8 2002 IL-8 concentration was increased significantly by 3- to 10-fold, with the highest increase found after exposure to hydrocarbons in the C9-C13 range. Hydrocarbons 115-127 C-X-C motif chemokine ligand 8 Homo sapiens 0-4 12115430-1 2002 The bacterial consortium MPD-M, isolated from sediment associated with Colombian mangrove roots, was effective in the treatment of hydrocarbons in water with salinities varying from 0 to 180 g L(-1). Hydrocarbons 131-143 mevalonate diphosphate decarboxylase Homo sapiens 25-28 12061888-3 2002 Compounds with short (<5 carbons) hydrocarbon chains at both C-2 and C-3 were generally inactive. Hydrocarbons 37-48 complement C2 Homo sapiens 64-75 12061888-5 2002 Linear molecules (i.e., compounds with a short hydrocarbon chain at C-2 or C-3 and a long hydrocarbon chain on C-3 or C-2, respectively) were more potent than the corresponding branched molecules with the same carbon load. Hydrocarbons 90-101 complement C3 Homo sapiens 111-114 12049528-1 2002 [reaction: see text] Results from density functional theory calculations (B3LYP/6-31+G) suggest that inversion of the monomer of 2-lithio-N-formylpyrrolidine (2) in coordinating ethereal solvent occurs with an activation barrier of 15.7 kcal/mol, while the inversion of the monomer in a noncoordinating hydrocarbon solvent is considerably slower. Hydrocarbons 303-314 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 76-79 12092812-2 2002 These hydrocarbons are the characteristic components of the cuticular hydrocarbons of the queen of the ant, Diacamma sp.. Hydrocarbons 70-82 solute carrier family 25 member 6 Homo sapiens 103-106 11974601-0 2002 Genetic study of the production of sexually dimorphic cuticular hydrocarbons in relation with the sex-determination gene transformer in Drosophila melanogaster. Hydrocarbons 64-76 transformer Drosophila melanogaster 121-132 12127040-3 2002 The objective of this research was to investigate effects of cigarette smoke related hydrocarbons (benzo(a)pyrene, BP) on uterine CYP1A1/2 and 1B1, enzymes involved in estrogen metabolism. Hydrocarbons 85-97 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 130-146 11948578-2 2002 The model, named SGB/NP, is based on a parameterization of the Surface Generalized Born continuum dielectric electrostatic model using explicit solvent free energy perturbation calculations and a newly developed nonpolar hydration free energy estimator motivated by the results of explicit solvent simulations of the thermodynamics of hydration of hydrocarbons. Hydrocarbons 348-360 glypican 3 Homo sapiens 17-23 11865713-1 2001 We have investigated the role of the Antennapedia and Bithorax complexes (ANT-C and BX-C) on the production of cuticular hydrocarbons in Drosophila melanogaster. Hydrocarbons 121-133 Ultrabithorax Drosophila melanogaster 54-62 11756230-1 2002 Occupational exposure to hydrocarbon solvents has been found to be associated with an increased risk of exocrine pancreatic cancer (EPC), the human tumor with the highest prevalence of K-ras mutations. Hydrocarbons 25-36 KRAS proto-oncogene, GTPase Homo sapiens 185-190 11756230-3 2002 We analysed the relationship between past occupational exposure to hydrocarbon solvents and mutations in codon 12 of the K-ras gene in 107 incident cases of EPC. Hydrocarbons 67-78 KRAS proto-oncogene, GTPase Homo sapiens 121-126 11756230-12 2002 The results raise the possibility that hydrocarbon solvents might be involved in the pathogenesis of EPC, possibly through indirect modulation of K-ras activation. Hydrocarbons 39-50 KRAS proto-oncogene, GTPase Homo sapiens 146-151 11741611-2 2001 Incorporation of different numbers of oxyethylene (-CH(2)CH(2)O-) units between long hydrocarbon chain at the C-1 and C-2 positions of the pseudoglyceryl skeleton improved the transfection efficiency considerably compared to the one in which the chains were connected via simple ether links. Hydrocarbons 85-96 heterogeneous nuclear ribonucleoprotein C Homo sapiens 110-113 11741611-2 2001 Incorporation of different numbers of oxyethylene (-CH(2)CH(2)O-) units between long hydrocarbon chain at the C-1 and C-2 positions of the pseudoglyceryl skeleton improved the transfection efficiency considerably compared to the one in which the chains were connected via simple ether links. Hydrocarbons 85-96 complement C2 Homo sapiens 118-121 11741611-3 2001 A pronounced improvement in the gene transfer efficiency was observed with the unsymmetrical cationic lipid 3 in which the long hydrocarbon at the C-1 position of the pseudoglyceryl segment is connected via two (-CH(2)CH(2)O-) units. Hydrocarbons 128-139 heterogeneous nuclear ribonucleoprotein C Homo sapiens 147-150 11741611-5 2001 This suggests that introduction of oxyethylene units between long hydrocarbon chains at the C-1 and C-2 positions of the pseudoglyceryl skeleton provides a novel strategy to achieve efficient gene transfer, especially in conditions where the presence of serum is critical. Hydrocarbons 66-77 heterogeneous nuclear ribonucleoprotein C Homo sapiens 92-95 11865713-1 2001 We have investigated the role of the Antennapedia and Bithorax complexes (ANT-C and BX-C) on the production of cuticular hydrocarbons in Drosophila melanogaster. Hydrocarbons 121-133 Antennapedia Drosophila melanogaster 74-79 11865713-1 2001 We have investigated the role of the Antennapedia and Bithorax complexes (ANT-C and BX-C) on the production of cuticular hydrocarbons in Drosophila melanogaster. Hydrocarbons 121-133 Ultrabithorax Drosophila melanogaster 84-88 11482965-7 2001 The presence of one double bond in a hydrocarbon chain as in oleyl-amides increases their hydrophilic character compared with that of saturated C18 derivatives. Hydrocarbons 37-48 Bardet-Biedl syndrome 9 Homo sapiens 144-147 11698167-0 2001 Analysis of interleukin-8 release from normal human epidermal keratinocytes exposed to aliphatic hydrocarbons: delivery of hydrocarbons to cell cultures via complexation with alpha-cyclodextrin. Hydrocarbons 97-109 C-X-C motif chemokine ligand 8 Homo sapiens 12-25 11698167-3 2001 The objective of this study was to examine the effects of individual hydrocarbon components found in these fuels on IL-8 production by NHEK. Hydrocarbons 69-80 C-X-C motif chemokine ligand 8 Homo sapiens 116-120 11577022-4 2001 Although Cyp1a1 was inducible in Ahr(+/+) by 3 micromol/L benzo(a)pyrene, a known hydrocarbon inducer, the protein was uninducible. Hydrocarbons 82-93 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 9-15 11597784-2 2001 To examine the ability of hydrocarbon carcinogens to induce p53 transcriptional activity in normal tissues, we have used transgenic mice in which LacZ transgene is driven by a p53 response element. Hydrocarbons 26-37 transformation related protein 53, pseudogene Mus musculus 60-63 11427889-4 2001 As an electrostatic crosslink within a hydrocarbon phase, such a hydrogen bond could alter the normal assembly and alignment of CFTR TM helices and/or impede their movement in response to substrate transport. Hydrocarbons 39-50 CF transmembrane conductance regulator Homo sapiens 128-132 11311466-1 2001 Microorganisms of Wadden Sea sediments are able to degrade hydrocarbons in suspensions. Hydrocarbons 59-71 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 25-28 11468922-0 2001 Hydrocarbon contamination of coastal sediments from the Sfax area (Tunisia), Mediterranean Sea. Hydrocarbons 0-11 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 91-94 11352722-9 2001 Restrained molecular dynamics/energy minimization calculations show that the hydrocarbon is intercalated from the major groove on the 3"-side of the modified base between base pairs A(6)-T(17) and C(7)-G(16) and confirm the syn glycosidic angle (58 degrees ) of the modified dA(6). Hydrocarbons 77-88 synemin Homo sapiens 224-227 11259300-7 2001 The PE and PC low-temperature phases denoted L(R1) and SGII, respectively, have different hydrocarbon chain packing. Hydrocarbons 90-101 semenogelin 2 Homo sapiens 55-59 11100299-5 2000 Environmental exposure to chlorinated hydrocarbons (e.g., DDT, PCB, pentachlorophenol, hexachlorocyclohexane) has been associated with an increase in rates of miscarriage and endometriosis. Hydrocarbons 38-50 pyruvate carboxylase Homo sapiens 63-66 11302163-0 2001 Synthesis of the enantiomers of some methyl-branched cuticular hydrocarbons of the ant, Diacamma sp.. Hydrocarbons 63-75 solute carrier family 25 member 6 Homo sapiens 19-22 11302163-2 2001 These methyl-branched alkanes are the characteristic components of the cuticular hydrocarbons of queen of the ant, Diacamma sp.. Hydrocarbons 81-93 solute carrier family 25 member 6 Homo sapiens 110-113 11181486-1 2001 Starvation potentiates the hepatotoxicity of a variety of small molecules, including chlorinated hydrocarbons and nitrosamines, through the induction of CYP2E1. Hydrocarbons 97-109 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 153-159 11163336-4 2001 2,3,7,8-Tetrachlorodibenzo-p-dioxin (dioxin; TCDD) is known to activate Cyp1a1 gene transcription by way of aromatic hydrocarbon response elements (AHREs). Hydrocarbons 117-128 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 72-78 23886277-4 2001 We hypothesized that ingestion of oil would result in an increase in levels of CYP1A1 in both targets, and predicted that the relationship between prolonged exposure and expression of CYP1A1 would reach a plateau indicative of continuous detoxification of hydrocarbons. Hydrocarbons 256-268 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 184-190 23886277-13 2001 Such interactions may obscure our ability to describe specific, quantitative, predictable, dose-response relationships between exposure to hydrocarbons and induction of CYP1A1, which are required of reliable biomarkers. Hydrocarbons 139-151 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 169-175 15954582-13 2001 Heavy hydrocarbons ranging from C10 up to C40 have been utilised in a thirty-day period for 72.4%. Hydrocarbons 6-18 homeobox C10 Homo sapiens 32-35 15954582-13 2001 Heavy hydrocarbons ranging from C10 up to C40 have been utilised in a thirty-day period for 72.4%. Hydrocarbons 6-18 CCR4-NOT transcription complex subunit 11 Homo sapiens 42-45 10984405-8 2000 The thermal stability of the alpha-helix is greater upon addition of the C(16) compared with the C(6) chain, which correlates to the extent of aggregation induced by the respective hydrocarbon chains. Hydrocarbons 181-192 complement C6 Homo sapiens 97-101 11056384-6 2000 These results, together with the finding that the N-glycans of CHO-EPO make little contact with the aromatic amino acid residues exposed on the protein surface, indicate that the inner regions including the galactose residues of the intramolecular N-glycans stabilize the protein conformation by clinging to the hydrophobic protein surface areas mainly made up of nonaromatic hydrocarbon groups. Hydrocarbons 376-387 erythropoietin Cricetulus griseus 67-70 10910964-0 2000 Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats. Hydrocarbons 22-34 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 52-90 11032419-1 2000 Aryl hydrocarbon receptor (AhR), a member of the bHLH-PAS family, is a ligand-activated transcription factor which plays an important role in normal liver development and in mediating the toxicity of polycyclic and halogenated aromatic hydrocarbon pollutants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. Hydrocarbons 5-16 aryl hydrocarbon receptor Homo sapiens 27-30 10854433-4 2000 The three-dimensional structure of recombinant human B-FABP in complex with oleic acid shows that the oleic acid hydrocarbon tail assumes a "U-shaped" conformation, whereas in the complex with docosahexaenoic acid the hydrocarbon tail adopts a helical conformation. Hydrocarbons 113-124 fatty acid binding protein 7 Homo sapiens 53-59 11693942-3 2000 Thus, SP administration appears to be a relatively simple and efficient means to reverse the immunotoxicity due to hydrocarbon exposure. Hydrocarbons 115-126 tachykinin precursor 1 Homo sapiens 6-8 11138794-0 2000 Task-related variation of postpharyngeal and cuticular hydrocarbon compositions in the ant Myrmicaria eumenoides. Hydrocarbons 55-66 solute carrier family 25 member 6 Homo sapiens 87-90 11138794-5 2000 Compositions of post-pharyngeal and cuticular hydrocarbons in individual ants varied simultaneously, but in different manner depending on the tasks of the ant (brood-tenders, foragers, scouts). Hydrocarbons 46-58 solute carrier family 25 member 6 Homo sapiens 73-76 10856296-0 2000 DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. Hydrocarbons 18-30 transformed mouse 3T3 cell double minute 2 Mus musculus 38-42 10856296-0 2000 DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. Hydrocarbons 18-30 transformation related protein 53, pseudogene Mus musculus 58-61 10856296-5 2000 However, we show that induction of mdm2 mRNA by BaP is entirely dependent upon aryl-hydrocarbon-induced genotoxicity and does not involve direct aryl-hydrocarbon receptor-mediated transcriptional activation of the mdm2 gene. Hydrocarbons 84-95 transformed mouse 3T3 cell double minute 2 Mus musculus 35-39 10856296-5 2000 However, we show that induction of mdm2 mRNA by BaP is entirely dependent upon aryl-hydrocarbon-induced genotoxicity and does not involve direct aryl-hydrocarbon receptor-mediated transcriptional activation of the mdm2 gene. Hydrocarbons 84-95 prohibitin 2 Mus musculus 48-51 10920187-11 2000 We suggest, therefore, that desat2 might play a control role in the biosynthesis of 5,9 HD hydrocarbons in Tai females and could explain the dienic hydrocarbon polymorphism in D. melanogaster. Hydrocarbons 91-103 Desaturase 2 Drosophila melanogaster 28-34 11460724-1 2000 The aryl hydrocarbon receptor nuclear translocator (ARNT) mediates aryl hydrocarbon signaling and toxicity by dimerizing with the ligand-activated aryl hydrocarbon receptor (AHR), forming a complex that binds specific DNA elements and alters transcription of target genes. Hydrocarbons 9-20 aryl hydrocarbon receptor nuclear translocator Oncorhynchus mykiss 52-56 10841534-0 2000 Enhanced metabolism of halogenated hydrocarbons in transgenic plants containing mammalian cytochrome P450 2E1. Hydrocarbons 35-47 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 90-109 10827979-10 2000 However, depending on temperature and hydrocarbon chain unsaturation, the lipid with the highest chain melting temperature converted to the gel state, as observed for the monounsaturated phosphatidylethanolamine (PE) in PC/PE/PS (4:4:1, mol/mol) at 25 degrees C. Hydrocarbons 38-49 procollagen C-endopeptidase enhancer Homo sapiens 220-228 10802196-5 2000 allows the separation of volatile hydrocarbons from C(1) to C(15) and the update of a database. Hydrocarbons 34-46 placenta associated 8 Homo sapiens 60-65 10748001-5 2000 For example, the planar hydrocarbon 1, 4-bis[2-(3,5-dichloropyridyl-oxy)]benzene activates mCAR and hPXR but has little or no activity on hCAR and mPXR. Hydrocarbons 24-35 coxsackie virus and adenovirus receptor Mus musculus 91-95 10748001-5 2000 For example, the planar hydrocarbon 1, 4-bis[2-(3,5-dichloropyridyl-oxy)]benzene activates mCAR and hPXR but has little or no activity on hCAR and mPXR. Hydrocarbons 24-35 nuclear receptor subfamily 1, group I, member 2 Mus musculus 147-151 10855726-0 2000 Biological degradation of selected hydrocarbons in an old PAH/creosote contaminated soil from a gas work site. Hydrocarbons 35-47 phenylalanine hydroxylase Homo sapiens 58-61 10782199-2 2000 The TWA concentrations of the hydrocarbons detected by CST/GC analysis were summed for comparison with the TWA concentration obtained from the direct-reading PID. Hydrocarbons 30-42 cystatin 12, pseudogene Homo sapiens 55-58 11225882-3 2000 The standard is applicable to the determination of hydrocarbons in the boiling range of n-decane (n-C10) up to n-tetracontane (n-C40) by GC. Hydrocarbons 51-63 homeobox C10 Homo sapiens 100-103 10782199-6 2000 Based on the linear regression analyses, the response of the portable PID was highly correlated to the CST/GC results for hydrocarbon mixtures encountered during various painting tasks. Hydrocarbons 122-133 metastasis associated 1 family member 2 Homo sapiens 70-73 10782199-6 2000 Based on the linear regression analyses, the response of the portable PID was highly correlated to the CST/GC results for hydrocarbon mixtures encountered during various painting tasks. Hydrocarbons 122-133 cystatin 12, pseudogene Homo sapiens 103-106 10776535-6 2000 The Cd1 value does not depend on DNA concentration and is determined only by the length of the hydrocarbon chain and the structure of the amphiphile ionic fragment. Hydrocarbons 95-106 CD1c molecule Homo sapiens 4-7 10663138-2 2000 Flies mutant for either the amorphic or the antimorphic allele of E(z) showed a similar hydrocarbon phenotype as those with the overlapping Df lxd(15) deficiency: decreased amounts of total hydrocarbons and especially unsaturated ones in both sexes. Hydrocarbons 88-99 Enhancer of zeste Drosophila melanogaster 66-70 10665397-4 2000 Biodegradation could be monitored well by soil biological parameters: the residual hydrocarbon content correlated positively with soil respiration, biomass-C (substrate-induced respiration), and with activities of soil dehydrogenase, urease and catalase. Hydrocarbons 83-94 catalase Homo sapiens 245-253 10663138-2 2000 Flies mutant for either the amorphic or the antimorphic allele of E(z) showed a similar hydrocarbon phenotype as those with the overlapping Df lxd(15) deficiency: decreased amounts of total hydrocarbons and especially unsaturated ones in both sexes. Hydrocarbons 190-202 Enhancer of zeste Drosophila melanogaster 66-70 10663138-5 2000 Thus the E(z) gene seems to affect hydrocarbon biosynthesis, especially its desaturation steps and even more so the female-specific desaturation step transforming 7-monoenic fatty acids to 7,11-dienic ones and leading to female pheromones. Hydrocarbons 35-46 Enhancer of zeste Drosophila melanogaster 9-13 10561081-0 2000 Modulation of CPP32 activity and induction of apoptosis in Human CEM X 174 lymphocytes by heptachlor, a chlorinated hydrocarbon insecticide. Hydrocarbons 116-127 caspase 3 Homo sapiens 14-19 11587443-11 2000 Our data illustrate the need for a better understanding of the role of nutrients in the degradation of high molecular weight hydrocarbons for the successful application of bioremediation at PAH contaminated sites. Hydrocarbons 125-137 phenylalanine hydroxylase Homo sapiens 190-193 10867371-7 2000 Results indicate that RGS testing at 6 and 16 h is a promising tool to differentiate between PAHs and chlorinated hydrocarbons often co-occurring in environmental samples. Hydrocarbons 114-126 paired like homeodomain 2 Homo sapiens 22-25 10631954-4 1999 The CD1b and CD1d-presented antigens differ in their fine structures but reveal a general motif in which a rigid hydrophilic cap is bound to two aliphatic hydrocarbon chains. Hydrocarbons 155-166 CD1b molecule Homo sapiens 4-8 10614669-1 2000 The aryl hydrocarbon receptor (AhR), so-designated based on the ability of the protein to bind with and be activated by polycyclic aromatic hydrocarbons (PAH) and related halogenated hydrocarbons, is part of an emerging family of ligand-activated transcriptional regulators that are distinct from the steroid-thyroid hormone receptor superfamily. Hydrocarbons 140-152 aryl-hydrocarbon receptor Mus musculus 4-29 10614669-1 2000 The aryl hydrocarbon receptor (AhR), so-designated based on the ability of the protein to bind with and be activated by polycyclic aromatic hydrocarbons (PAH) and related halogenated hydrocarbons, is part of an emerging family of ligand-activated transcriptional regulators that are distinct from the steroid-thyroid hormone receptor superfamily. Hydrocarbons 140-152 aryl-hydrocarbon receptor Mus musculus 31-34 10631954-4 1999 The CD1b and CD1d-presented antigens differ in their fine structures but reveal a general motif in which a rigid hydrophilic cap is bound to two aliphatic hydrocarbon chains. Hydrocarbons 155-166 CD1d molecule Homo sapiens 13-17 10496959-0 1999 Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Hydrocarbons 19-30 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 39-59 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 aryl hydrocarbon receptor nuclear translocator Mus musculus 43-47 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 aryl hydrocarbon receptor nuclear translocator Mus musculus 82-86 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 aryl-hydrocarbon receptor Mus musculus 87-90 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 aryl-hydrocarbon receptor Mus musculus 152-177 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 aryl-hydrocarbon receptor Mus musculus 179-182 10630574-1 1999 The aryl hydrocarbon nuclear translocator (Arnt) is a basic helix-loop-helix (per/Arnt/Ahr/sim) PAS-containing protein that can heterodimerize with the aryl hydrocarbon receptor (AhR), the hypoxia-inducible factor-1 alpha, and other PAS-containing proteins to form transcriptionally active complexes. Hydrocarbons 9-20 hypoxia inducible factor 1, alpha subunit Mus musculus 189-221 10574678-1 1999 Cytochrome P4502E1 (CYP2E1) is involved in metabolic activation of carcinogenic nitrosamines, benzene and low molecular weight halogenated hydrocarbons. Hydrocarbons 139-151 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 0-18 10574678-1 1999 Cytochrome P4502E1 (CYP2E1) is involved in metabolic activation of carcinogenic nitrosamines, benzene and low molecular weight halogenated hydrocarbons. Hydrocarbons 139-151 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 20-26 15822265-4 1999 A comparison of the infrared transmission and ATR spectra reveals that the hydrocarbon chains were tilted considerably in the LB film. Hydrocarbons 75-86 ATR serine/threonine kinase Homo sapiens 46-49 10496959-0 1999 Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Hydrocarbons 19-30 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 80-86 10214966-4 1999 Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. Hydrocarbons 118-130 ribosomal protein S6 kinase B1 Rattus norvegicus 207-213 10499085-1 1999 Photoexcited iron porphyrins can be used to mimic the catalytic activity of cytochrome P-450 oxygenases both in the reduction of halogenated alkanes and in the oxidation of hydrocarbons by O2 itself at room temperature and atmospheric pressure. Hydrocarbons 173-185 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 76-92 10591537-4 1999 The sequence of 3.18 kb upstream of exon 1 reveals numerous consensus transcription factor-binding sites, some of which were shown to be important in the positive and negative control of Aldh3a1 gene expression; these include seven aromatic hydrocarbon response elements (AHREs), an electrophile response element (EPRE), and AP-1, C/EBP beta, c/EBP alpha, NF-kappaB, Sp1, and NF-1 putative binding sites. Hydrocarbons 241-252 aldehyde dehydrogenase family 3, subfamily A1 Mus musculus 187-194 10488687-0 1999 CYP1A1 and CYP1B1, two hydrocarbon-inducible cytochromes P450, are constitutively expressed in neonate and adult goat liver, lung and kidney. Hydrocarbons 23-34 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 0-6 10488687-0 1999 CYP1A1 and CYP1B1, two hydrocarbon-inducible cytochromes P450, are constitutively expressed in neonate and adult goat liver, lung and kidney. Hydrocarbons 23-34 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 11-17 10488687-3 1999 Immunoblotting analysis using polyclonal antibodies against rat CYP1B1, and mouse CYP1B1, polyaromatic hydrocarbon-regulated P450"s, revealed that goat orthologs of CYP1A1 and CYP1B1 are expressed constitutively in goats. Hydrocarbons 103-114 cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus 82-88 10488687-3 1999 Immunoblotting analysis using polyclonal antibodies against rat CYP1B1, and mouse CYP1B1, polyaromatic hydrocarbon-regulated P450"s, revealed that goat orthologs of CYP1A1 and CYP1B1 are expressed constitutively in goats. Hydrocarbons 103-114 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 165-171 10488687-3 1999 Immunoblotting analysis using polyclonal antibodies against rat CYP1B1, and mouse CYP1B1, polyaromatic hydrocarbon-regulated P450"s, revealed that goat orthologs of CYP1A1 and CYP1B1 are expressed constitutively in goats. Hydrocarbons 103-114 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 82-88 9872791-4 1999 Several clone sequences clustered to rDNA sequences obtained from a molecular study of an anaerobic aquifer contaminated with hydrocarbons and chlorinated solvents (Dojka et al., Appl. Hydrocarbons 126-138 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Homo sapiens 179-183 9950884-0 1999 NK1-receptor activation prevents hydrocarbon-induced lung injury in mice. Hydrocarbons 33-44 tachykinin receptor 1 Mus musculus 0-12 9950884-8 1999 These data indicate that NK1-receptor activation may have a protective role in preventing the development of hydrocarbon-induced lung injury, possibly through the modulation of bronchiolar epithelial function. Hydrocarbons 109-120 tachykinin receptor 1 Mus musculus 25-37 10402558-2 1999 In our laboratory, we demonstrated using aromatic hydrocarbon-responsive receptor knock-out (AHR-(-)/-) mice that both piperonyl butoxide (PBO) and acenaphtyhlene (ACN) are AHR-independent inducers of murine CYP1A2 and CYP1B1 mRNA. Hydrocarbons 50-61 aryl-hydrocarbon receptor Mus musculus 93-96 10493257-1 1999 CYP1A1 plays an important role in the metabolism of polycyclic hydrocarbons that occur in the environment and several studies suggest that the genetic polymorphism of the gene may play a role in the predisposition to cancer. Hydrocarbons 63-75 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 0-6 10402558-2 1999 In our laboratory, we demonstrated using aromatic hydrocarbon-responsive receptor knock-out (AHR-(-)/-) mice that both piperonyl butoxide (PBO) and acenaphtyhlene (ACN) are AHR-independent inducers of murine CYP1A2 and CYP1B1 mRNA. Hydrocarbons 50-61 aryl-hydrocarbon receptor Mus musculus 173-176 9731718-1 1998 Because aryl hydrocarbon hydroxylase (AHH) is considered to be responsible for the activation of benzo(a)pyrene and other polyaromatic hydrocarbons in cigarette smoke to carcinogens, it is important to examine CYP1A1 (AHH) activity in the determination of susceptibility to lung cancer. Hydrocarbons 135-147 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 8-36 9865727-4 1998 The induction of transcription of an aryl hydrocarbon-responsive reporter vector containing the CYP1A1 promoter by TCDD was likewise inhibited by resveratrol. Hydrocarbons 42-53 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 96-102 11542820-4 1998 The existence of the 3.4 micrometers feature implies the presence of relatively short-chained, aliphatic hydrocarbon materials (-CH2-/-CH3 approximately = 2-2.5) in the circumstellar environment around CRL 618. Hydrocarbons 105-116 interleukin 31 receptor A Homo sapiens 202-205 9819208-5 1998 Above this threshold concentration, apoA-I penetrates within the monolayer (i.e., part of apoA-I crosses the PL polar headgroup/hydrocarbon chain interface). Hydrocarbons 128-139 apolipoprotein A1 Homo sapiens 36-42 9819208-5 1998 Above this threshold concentration, apoA-I penetrates within the monolayer (i.e., part of apoA-I crosses the PL polar headgroup/hydrocarbon chain interface). Hydrocarbons 128-139 apolipoprotein A1 Homo sapiens 90-96 9731718-1 1998 Because aryl hydrocarbon hydroxylase (AHH) is considered to be responsible for the activation of benzo(a)pyrene and other polyaromatic hydrocarbons in cigarette smoke to carcinogens, it is important to examine CYP1A1 (AHH) activity in the determination of susceptibility to lung cancer. Hydrocarbons 135-147 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 38-41 9698073-8 1998 These results suggest that the chemopreventive effect of curcumin may be due, in part, to its ability to compete with aryl hydrocarbons for both the AhR and CYP1A1. Hydrocarbons 123-135 aryl hydrocarbon receptor Homo sapiens 149-152 9675139-0 1998 Positional specificity of rabbit CYP4B1 for omega-hydroxylation1 of short-medium chain fatty acids and hydrocarbons. Hydrocarbons 103-115 cytochrome P450 4B1 Oryctolagus cuniculus 33-39 9675139-5 1998 This suggests the presence of a dominant hydrocarbon binding site which effectively restricts the access of short-medium chain n-alkyl substrates to the perferryl species in the active site of rabbit CYP4B1. Hydrocarbons 41-52 cytochrome P450 4B1 Oryctolagus cuniculus 200-206 9698073-8 1998 These results suggest that the chemopreventive effect of curcumin may be due, in part, to its ability to compete with aryl hydrocarbons for both the AhR and CYP1A1. Hydrocarbons 123-135 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 157-163 29710916-1 1998 Extraordinary solubility in hydrocarbons is exhibited by the novel superaggregate Li33 H17 (OtBu)16 , which crystallizes from photolyzed solutions of lithium tert-butoxide and tert-butyllithium (ROLi:RLi>=7:3). Hydrocarbons 28-40 ATP binding cassette subfamily E member 1 Homo sapiens 200-203 9717460-3 1998 Polycyclic aromatic hydrocarbons regulate the gene expression by binding the cytosolic aryl hydrocarbon receptor and its translocation to the nucleus where it forms a ternary complex with aryl hydrocarbon nuclear translocator. Hydrocarbons 20-31 aryl hydrocarbon receptor Homo sapiens 87-112 9614203-1 1998 Glucocorticoids (GCs) repress both basal and polyaromatic hydrocarbon-induced expression of the glutathione S-transferase Ya1 gene (gstA2) in isolated rat hepatocytes and rat liver in vivo. Hydrocarbons 58-69 glutathione S-transferase alpha 2 Rattus norvegicus 96-125 9614203-1 1998 Glucocorticoids (GCs) repress both basal and polyaromatic hydrocarbon-induced expression of the glutathione S-transferase Ya1 gene (gstA2) in isolated rat hepatocytes and rat liver in vivo. Hydrocarbons 58-69 glutathione S-transferase alpha 2 Rattus norvegicus 132-137 9701998-4 1998 Of the isozymes, CYP2E1 is a low-km isozyme and has a high affinity for volatile hydrocarbons of low molecular mass, and is primarily involved in the metabolism of alcohol and organic solvents. Hydrocarbons 81-93 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 17-23 29711017-1 1998 13 C NMR spectroscopy and computer simulations have shown that the chain length of hydrocarbons has a surprising effect on where these molecules reside in the zeolite FER. Hydrocarbons 83-95 FER tyrosine kinase Homo sapiens 167-170 9717460-4 1998 The ternary complex PAH-AHR-ARNT acts as a transcription factor and binds aromatic hydrocarbon responsive element to increase the expression of CYP1A1 gene. Hydrocarbons 83-94 phenylalanine hydroxylase Homo sapiens 20-23 9717460-4 1998 The ternary complex PAH-AHR-ARNT acts as a transcription factor and binds aromatic hydrocarbon responsive element to increase the expression of CYP1A1 gene. Hydrocarbons 83-94 aryl hydrocarbon receptor Homo sapiens 24-27 9717460-4 1998 The ternary complex PAH-AHR-ARNT acts as a transcription factor and binds aromatic hydrocarbon responsive element to increase the expression of CYP1A1 gene. Hydrocarbons 83-94 aryl hydrocarbon receptor nuclear translocator Homo sapiens 28-32 9717460-4 1998 The ternary complex PAH-AHR-ARNT acts as a transcription factor and binds aromatic hydrocarbon responsive element to increase the expression of CYP1A1 gene. Hydrocarbons 83-94 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 144-150 9559668-1 1998 The aryl hydrocarbon receptor mediates the transcriptional response to a variety of hydrocarbons of members of the aryl hydrocarbon gene battery. Hydrocarbons 84-96 aryl-hydrocarbon receptor Mus musculus 4-29 9599728-1 1998 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most potent member of a class of chlorinated hydrocarbons that interact with the aryl hydrocarbon receptor (AhR). Hydrocarbons 95-107 aryl hydrocarbon receptor Homo sapiens 131-156 9599728-1 1998 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most potent member of a class of chlorinated hydrocarbons that interact with the aryl hydrocarbon receptor (AhR). Hydrocarbons 95-107 aryl hydrocarbon receptor Homo sapiens 158-161 9514075-1 1998 The tumor-associated aldehyde dehydrogenase 3 (ALDH3) and the glutathione transferase (GST)Ya form are coded by members of the Ah (aryl hydrocarbon) battery group of genes activated in the liver by polycyclic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Hydrocarbons 136-147 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 21-45 9547000-5 1998 The effect of A beta peptides on fluidity of the phospholipid bilayer is more pronounced in the hydrocarbon core (labeled with the fluorescence probe 1,6-diphenylhexa-1,3,5-triene) than in the region of the hydrophilic heads (labeled with the fluorescence probe 1-[4"-(trimethylamino)phenyl]-6-phenylhexa-1,3,5-triene). Hydrocarbons 96-107 amyloid beta precursor protein Homo sapiens 14-20 9514075-1 1998 The tumor-associated aldehyde dehydrogenase 3 (ALDH3) and the glutathione transferase (GST)Ya form are coded by members of the Ah (aryl hydrocarbon) battery group of genes activated in the liver by polycyclic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Hydrocarbons 136-147 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 47-52 9514075-1 1998 The tumor-associated aldehyde dehydrogenase 3 (ALDH3) and the glutathione transferase (GST)Ya form are coded by members of the Ah (aryl hydrocarbon) battery group of genes activated in the liver by polycyclic hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Hydrocarbons 136-147 glutathione S-transferase alpha 4 Rattus norvegicus 62-85 9343374-0 1997 Distal site and surface mutations of cytochrome P450 1A2 markedly enhance dehalogenation of chlorinated hydrocarbons. Hydrocarbons 104-116 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 37-56 9550098-6 1997 Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT. Hydrocarbons 75-87 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 27-34 9550098-6 1997 Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT. Hydrocarbons 75-87 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 47-53 9550098-6 1997 Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT. Hydrocarbons 131-143 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 27-34 9550098-6 1997 Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT. Hydrocarbons 131-143 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 47-53 9465551-1 1997 Since aryl hydrocarbon hydroxylase (AHH) is considered to be responsible for the activation of benzo(a)pyrene (BP) and other polyaromatic hydrocarbons in cigarette smoke to carcinogens, it is important to examine AHH activity in the determination of susceptibility to lung cancer. Hydrocarbons 138-150 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 6-34 9398442-1 1997 We used homologous recombination in embryonic stem cells to generate mice heterozygous for an aryl hydrocarbon nuclear translocator (ARNT) null mutation. Hydrocarbons 99-110 aryl hydrocarbon receptor nuclear translocator Mus musculus 133-137 9348725-13 1997 These results revealed that changes in plasma lipoproteins can serve as sensitive and simple markers for liver disorders caused by chlorinated hydrocarbon solvents such as CCl4, CHCl3, or CH2Cl2. Hydrocarbons 143-154 C-C motif chemokine ligand 4 Rattus norvegicus 172-176 9017186-10 1997 The result was supported by spin label experiments that indicated F35 of NG(28-43) interacted strongly with the hydrocarbon interior of micelle. Hydrocarbons 112-123 neurogranin Homo sapiens 73-75 9126279-2 1997 After binding aryl hydrocarbons, the receptor releases the 90-kDa heat shock protein and forms a dimer with the Arnt protein capable of binding at xenobiotic-responsive elements (XREs) and stimulating the transcription of genes involved in the metabolism of aryl hydrocarbons. Hydrocarbons 19-31 aryl hydrocarbon receptor nuclear translocator Mus musculus 112-116 9126279-2 1997 After binding aryl hydrocarbons, the receptor releases the 90-kDa heat shock protein and forms a dimer with the Arnt protein capable of binding at xenobiotic-responsive elements (XREs) and stimulating the transcription of genes involved in the metabolism of aryl hydrocarbons. Hydrocarbons 263-275 aryl hydrocarbon receptor nuclear translocator Mus musculus 112-116 9221576-10 1997 Toxins can be also important for the development of HCC (in particular aflatoxins, chlorinated hydrocarbons, pesticides). Hydrocarbons 95-107 HCC Homo sapiens 52-55 9284531-13 1997 Thus, SP administration appears to be a relatively simple and efficient means to reverse the immunotoxicity due to hydrocarbon exposure. Hydrocarbons 115-126 tachykinin 1 Mus musculus 6-8 9006115-2 1996 The resulting DNA adducts correspond to a trans ring-opening of the oxiranes at the C-10 position of the hydrocarbon by the exocyclic amino group of the purine (the relative stereochemistry between the C-9 and C-10 substituents is trans). Hydrocarbons 105-116 homeobox C10 Homo sapiens 84-88 9523452-1 1997 After eighteen months of active remediation at a JP-4 jet-fuel spill, a residual of unremediated hydrocarbon remained. Hydrocarbons 97-108 junctophilin 4 Homo sapiens 49-53 8978552-0 1996 Comparison of Solubilization of Hydrocarbons in (PEO-PPO) Diblock versus (PEO-PPO-PEO) Triblock Copolymer Micelles The solubilization of hydrocarbons by micelles formed of diblock and symmetric triblock copolymers in water are compared in the framework of a mean-field theory of solubilization. Hydrocarbons 32-44 protoporphyrinogen oxidase Homo sapiens 53-56 9006115-2 1996 The resulting DNA adducts correspond to a trans ring-opening of the oxiranes at the C-10 position of the hydrocarbon by the exocyclic amino group of the purine (the relative stereochemistry between the C-9 and C-10 substituents is trans). Hydrocarbons 105-116 complement C9 Homo sapiens 202-205 9006115-2 1996 The resulting DNA adducts correspond to a trans ring-opening of the oxiranes at the C-10 position of the hydrocarbon by the exocyclic amino group of the purine (the relative stereochemistry between the C-9 and C-10 substituents is trans). Hydrocarbons 105-116 homeobox C10 Homo sapiens 210-214 8816425-5 1996 By fluorescence polarization and infrared spectroscopic measurements we found that zinc addition leads to decreased fluidity of the hydrocarbon chains of LPS. Hydrocarbons 132-143 interferon regulatory factor 6 Homo sapiens 154-157 8816425-7 1996 Our studies suggest that the synergistic effect of zinc on monokine induction by LPS is caused by direct interaction of zinc with LPS altering the fluidity of the hydrocarbon chains. Hydrocarbons 163-174 interferon regulatory factor 6 Homo sapiens 81-84 8816425-7 1996 Our studies suggest that the synergistic effect of zinc on monokine induction by LPS is caused by direct interaction of zinc with LPS altering the fluidity of the hydrocarbon chains. Hydrocarbons 163-174 interferon regulatory factor 6 Homo sapiens 130-133 8759031-5 1996 The pattern of hydrocarbon inducibility was atypical in that BaP was a more effective inducer of CYP1A1 gene expression than TCDD, and both hydrocarbons induced aryl hydrocarbon hydroxylase (AHH) activity, but not ethoxyresorufin-O-deethylase activity. Hydrocarbons 15-26 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 97-103 8759031-5 1996 The pattern of hydrocarbon inducibility was atypical in that BaP was a more effective inducer of CYP1A1 gene expression than TCDD, and both hydrocarbons induced aryl hydrocarbon hydroxylase (AHH) activity, but not ethoxyresorufin-O-deethylase activity. Hydrocarbons 15-26 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 191-194 8759031-5 1996 The pattern of hydrocarbon inducibility was atypical in that BaP was a more effective inducer of CYP1A1 gene expression than TCDD, and both hydrocarbons induced aryl hydrocarbon hydroxylase (AHH) activity, but not ethoxyresorufin-O-deethylase activity. Hydrocarbons 140-152 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 161-189 8759031-5 1996 The pattern of hydrocarbon inducibility was atypical in that BaP was a more effective inducer of CYP1A1 gene expression than TCDD, and both hydrocarbons induced aryl hydrocarbon hydroxylase (AHH) activity, but not ethoxyresorufin-O-deethylase activity. Hydrocarbons 140-152 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 191-194 8570624-7 1996 The hPAH-AR mice will serve as a valuable model for studying the sex- and age-invariant expression of liver-specific genes, particularly those involved in the activation of environmental hepatocarcinogens such as the aromatic hydrocarbons. Hydrocarbons 226-238 phenylalanine hydroxylase Homo sapiens 4-8 8772423-1 1996 Z-(11)-pentacosene, Drosophila virilis sex pheromone, is predominant among the female cuticular hydrocarbons and can elicit male courtship behaviours. Hydrocarbons 96-108 Dvir\11-P Drosophila virilis 0-18 8608954-2 1996 Decreased aryl hydrocarbon (Ah)-responsiveness in the CS and C1O BaPr cells was characterized by lower (80 to 900/o) induction of CYP1A1-dependent activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), lower levels of the nuclear Ah receptor complex and significantly decreased Ah receptor mRNA levels. Hydrocarbons 15-26 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 130-136 11667330-2 1996 The radical-initiated reaction of amine-boranes and phosphine-boranes, LBH(3) (L = R(3)N, R(3)P) with aliphatic nitro compounds has been investigated in order to explore the possibility of reducing tertiary nitroalkanes to the corresponding hydrocarbons. Hydrocarbons 241-253 LBH regulator of WNT signaling pathway Homo sapiens 71-74 21619230-10 1996 Good agreement was obtained between a 45-min SPME and methylene chloride extraction for the determination of PAH concentrations in creosote-contaminated water, demonstrating that SPME is a useful technique for the rapid determination of hydrocarbons in complex water matrices. Hydrocarbons 237-249 phenylalanine hydroxylase Homo sapiens 109-112 15091439-0 1996 Chlorinated hydrocarbons in coastal bottom sediments of the Japan Sea. Hydrocarbons 12-24 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 66-69 8742826-0 1996 Purification of adult Drosophila melanogaster lipophorin and its role in hydrocarbon transport. Hydrocarbons 73-84 apolipophorin Drosophila melanogaster 46-56 8742826-7 1996 These results suggest that hydrocarbons synthesized at an internal site, possibly in oenocytes, may be transported to the cuticle of the flies by lipophorin. Hydrocarbons 27-39 apolipophorin Drosophila melanogaster 146-156 15091439-1 1996 Data on distribution of chlorinated hydrocarbons in coastal bottom sediments of different areas of the Japan Sea are presented. Hydrocarbons 36-48 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 109-112 8571359-2 1995 Many xenobiotics including pesticides, nitrosamines, polycyclic aromatic hydrocarbons and halogenated hydrocarbons, require bioactivation by P450 enzymes to elicit toxicity. Hydrocarbons 73-85 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 141-145 8606364-8 1995 Correction of PHA for those temperature effects considered to be independent of lipid chain order (i.e., enthalpy of transfer from water to decane and activation energy for diffusion in bulk hydrocarbon) yielded an improved correlation (kappa = -11.7 +/- 0.5 (r = 0.96)). Hydrocarbons 191-202 lamin B receptor Homo sapiens 14-17 7479797-0 1995 Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites. Hydrocarbons 18-29 Harvey rat sarcoma virus oncogene Mus musculus 54-61 7473857-5 1995 In contrast, the chlorinated hydrocarbon pesticides, such as DDT, dieldrin, chlordane, and mirex, cause almost exclusively the induction of isoforms of the CYP2B (and to a lesser extent the CYP3A) subfamilies. Hydrocarbons 29-40 cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus 190-195 8543324-2 1995 Various aspects discussed include global protein problem, microbes as potential sources of food and feed with its advantages and disadvantages, salient features in selection of microorganisms for SCP production, production of SCP from petroleum based hydrocarbons, renewable raw materials like agricultural and forestry residues, industrial by-products and wastes, nutritional and safety evaluation of SCP, ways of improving SCP production, economics of SCP production and the present status of SCP in India. Hydrocarbons 251-263 urocortin 3 Homo sapiens 226-229 7577946-5 1995 The hydrocarbon attached at dA5 orients toward the 3" end of the modified strand (i.e., dC6 direction) and intercalates between and parallel to bases of dG13 and dG14 of the complementary strand directly opposite dC6 and dA5, respectively. Hydrocarbons 4-15 antennal protein 5 Drosophila melanogaster 28-31 7577946-5 1995 The hydrocarbon attached at dA5 orients toward the 3" end of the modified strand (i.e., dC6 direction) and intercalates between and parallel to bases of dG13 and dG14 of the complementary strand directly opposite dC6 and dA5, respectively. Hydrocarbons 4-15 labial associated factor Drosophila melanogaster 88-91 7577946-5 1995 The hydrocarbon attached at dA5 orients toward the 3" end of the modified strand (i.e., dC6 direction) and intercalates between and parallel to bases of dG13 and dG14 of the complementary strand directly opposite dC6 and dA5, respectively. Hydrocarbons 4-15 Golgi complex-localized glycoprotein 1 Drosophila melanogaster 153-157 7577946-5 1995 The hydrocarbon attached at dA5 orients toward the 3" end of the modified strand (i.e., dC6 direction) and intercalates between and parallel to bases of dG13 and dG14 of the complementary strand directly opposite dC6 and dA5, respectively. Hydrocarbons 4-15 labial associated factor Drosophila melanogaster 213-216 7577946-5 1995 The hydrocarbon attached at dA5 orients toward the 3" end of the modified strand (i.e., dC6 direction) and intercalates between and parallel to bases of dG13 and dG14 of the complementary strand directly opposite dC6 and dA5, respectively. Hydrocarbons 4-15 antennal protein 5 Drosophila melanogaster 221-224 7577946-6 1995 The edge of the hydrocarbon bearing H11 and H12 is positioned between the imino protons of dG13 and dG14 in the interior of the duplex, whereas H4 and H5 at the opposite edge are positioned near the sugar H1" and H2" protons of dG13 and facing the exterior of the duplex. Hydrocarbons 16-27 Golgi complex-localized glycoprotein 1 Drosophila melanogaster 91-95 7577946-6 1995 The edge of the hydrocarbon bearing H11 and H12 is positioned between the imino protons of dG13 and dG14 in the interior of the duplex, whereas H4 and H5 at the opposite edge are positioned near the sugar H1" and H2" protons of dG13 and facing the exterior of the duplex. Hydrocarbons 16-27 Golgi complex-localized glycoprotein 1 Drosophila melanogaster 228-232 8543324-2 1995 Various aspects discussed include global protein problem, microbes as potential sources of food and feed with its advantages and disadvantages, salient features in selection of microorganisms for SCP production, production of SCP from petroleum based hydrocarbons, renewable raw materials like agricultural and forestry residues, industrial by-products and wastes, nutritional and safety evaluation of SCP, ways of improving SCP production, economics of SCP production and the present status of SCP in India. Hydrocarbons 251-263 urocortin 3 Homo sapiens 226-229 8543324-2 1995 Various aspects discussed include global protein problem, microbes as potential sources of food and feed with its advantages and disadvantages, salient features in selection of microorganisms for SCP production, production of SCP from petroleum based hydrocarbons, renewable raw materials like agricultural and forestry residues, industrial by-products and wastes, nutritional and safety evaluation of SCP, ways of improving SCP production, economics of SCP production and the present status of SCP in India. Hydrocarbons 251-263 urocortin 3 Homo sapiens 226-229 8543324-2 1995 Various aspects discussed include global protein problem, microbes as potential sources of food and feed with its advantages and disadvantages, salient features in selection of microorganisms for SCP production, production of SCP from petroleum based hydrocarbons, renewable raw materials like agricultural and forestry residues, industrial by-products and wastes, nutritional and safety evaluation of SCP, ways of improving SCP production, economics of SCP production and the present status of SCP in India. Hydrocarbons 251-263 urocortin 3 Homo sapiens 226-229 8543324-2 1995 Various aspects discussed include global protein problem, microbes as potential sources of food and feed with its advantages and disadvantages, salient features in selection of microorganisms for SCP production, production of SCP from petroleum based hydrocarbons, renewable raw materials like agricultural and forestry residues, industrial by-products and wastes, nutritional and safety evaluation of SCP, ways of improving SCP production, economics of SCP production and the present status of SCP in India. Hydrocarbons 251-263 urocortin 3 Homo sapiens 226-229 7847667-3 1994 The molecular explanation for this observation appears to be related to the fact that cholesterol and DHPs occupy a similar molecular location in the membrane hydrocarbon core (Fig. Hydrocarbons 159-170 deoxyhypusine synthase Homo sapiens 102-106 11539217-3 1995 New infrared electronic transitions of C2 and C3 were discovered by emission spectroscopy of hydrocarbon dicharges. Hydrocarbons 93-104 complement C2 Homo sapiens 39-48 11540308-10 1995 The synthesis of laboratory analogs of meteoritic hydrocarbons through plasma hydrogenation of PAH species is underway, as is chemical analysis of those analogs. Hydrocarbons 50-62 phenylalanine hydroxylase Homo sapiens 95-98 7695328-2 1995 The compounds, alkanoylcholines with hydrocarbon chains of 10 to 14 carbon atoms, are hydrolyzed by butyrylcholine esterase, which is present in human serum and mucosal membranes. Hydrocarbons 37-48 butyrylcholinesterase Homo sapiens 100-123 15736342-2 1994 During this study, the GMR&D remote sensor was used to measure the carbon monoxide (CO) and hydrocarbon (HC) emissions from approximately 15,000 vehicles. Hydrocarbons 96-107 colony stimulating factor 2 receptor subunit alpha Homo sapiens 23-26 7895165-3 1994 In vitro, CLIP dissociation from DR alpha beta dimers occurs at different rates depending on the allele, and is facilitated by low pH and by detergents containing 8-10 carbon unbranched hydrocarbons, or by primary aliphatic amines or carboxylic acids. Hydrocarbons 186-198 CAP-Gly domain containing linker protein 1 Homo sapiens 10-14 7895165-3 1994 In vitro, CLIP dissociation from DR alpha beta dimers occurs at different rates depending on the allele, and is facilitated by low pH and by detergents containing 8-10 carbon unbranched hydrocarbons, or by primary aliphatic amines or carboxylic acids. Hydrocarbons 186-198 solute carrier family 26 member 3 Homo sapiens 33-41 15736342-2 1994 During this study, the GMR&D remote sensor was used to measure the carbon monoxide (CO) and hydrocarbon (HC) emissions from approximately 15,000 vehicles. Hydrocarbons 109-111 colony stimulating factor 2 receptor subunit alpha Homo sapiens 23-26 8181476-9 1994 The epsilon Ahx hydrocarbon chain rests flanked by Pro33, Tyr64, Tyr72 and Tyr74 on one side and Phe36 on the other. Hydrocarbons 16-27 nuclear receptor subfamily 0 group B member 1 Homo sapiens 12-15 8074202-8 1994 In conclusion, a monocarboxylic acid with several numbers of hydrocarbons was required for insulin or glucagon secretion. Hydrocarbons 61-73 LOC105613195 Ovis aries 91-98 7964927-1 1994 The semiempirical MNDO method has been used in order to examine the variation of the molecular properties of hydrocarbons CnH2n + 2 (with 1 < or = n < or = 19) and ethylene oxide chains CH3(CH2CH2O)mCH3 (with 1 < or = m < or = 19) as a function of their molecular length. Hydrocarbons 109-121 caspase 7 Mus musculus 192-195 7964927-1 1994 The semiempirical MNDO method has been used in order to examine the variation of the molecular properties of hydrocarbons CnH2n + 2 (with 1 < or = n < or = 19) and ethylene oxide chains CH3(CH2CH2O)mCH3 (with 1 < or = m < or = 19) as a function of their molecular length. Hydrocarbons 109-121 caspase 7 Mus musculus 204-208 8202380-0 1994 Aryl hydrocarbon-induced interactions at multiple DNA elements of diverse sequence--a multicomponent mechanism for activation of cytochrome P4501A1 (CYP1A1) gene transcription. Hydrocarbons 5-16 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 129-147 7850393-0 1994 Mutagenic and carcinogenic risk of oxygen containing chlorinated C-3 hydrocarbons: putative secondary products of C-3 chlorohydrocarbons and chlorination of water. Hydrocarbons 69-81 complement C3 Homo sapiens 65-68 7850393-0 1994 Mutagenic and carcinogenic risk of oxygen containing chlorinated C-3 hydrocarbons: putative secondary products of C-3 chlorohydrocarbons and chlorination of water. Hydrocarbons 69-81 complement C3 Homo sapiens 114-117 7918381-7 1994 65 degrees C with a spin-label in the lipid head group and an accompanying increase in mobility at the same temperature with spin-labels positioned toward the terminal methyl of the hydrocarbon chain. Hydrocarbons 182-193 spindlin 1 Homo sapiens 125-129 7922152-2 1994 The Adriatic Sea, as semienclosed body of water, is of special interest for an evaluation of the entry, extent and fate of the pollution by chlorinated hydrocarbons. Hydrocarbons 152-164 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 13-16 22165944-0 1994 Reactor Trap To Remove Hydrocarbons from Engine Exhaust during Cold Start. Hydrocarbons 23-35 TRAP Homo sapiens 8-12 8022408-1 1994 The major cytochrome P450 (P450EF) in the mouse embryo fibroblast C3H/10T1/2CL8 (10T1/2) cell line, which is very active in polycyclic aromatic hydrocarbon metabolism, is immunologically distinct from known P450 families but shares homology with an adrenocorticotropin hormone-regulated P450 from rat adrenal glands (P450RAP). Hydrocarbons 144-155 cytochrome P450, family 1, subfamily b, polypeptide 1 Rattus norvegicus 317-324 8202380-0 1994 Aryl hydrocarbon-induced interactions at multiple DNA elements of diverse sequence--a multicomponent mechanism for activation of cytochrome P4501A1 (CYP1A1) gene transcription. Hydrocarbons 5-16 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 149-155 8202380-1 1994 In vivo footprinting experiments, augmented with gel shift and transfection analyses suggest that activation of the CYP1A1 gene by aryl hydrocarbons may be a multicomponent process. Hydrocarbons 136-148 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 116-122 8184439-1 1994 In vivo exposure of B6C3F1 mice to the hepatotoxic chlorinated hydrocarbon, CCl4, suppresses T-cell-dependent humoral immune responses to sRBC. Hydrocarbons 63-74 chemokine (C-C motif) ligand 4 Mus musculus 76-80 8149489-1 1994 The present study provides the first evidence that a mammalian liver cytosolic enzyme, aldehyde oxidase, has an ability to reduce arene oxides to the parent hydrocarbons under anaerobic conditions. Hydrocarbons 157-169 aldehyde oxidase 1 Homo sapiens 87-103 7922137-2 1994 In harmony with our studies on the activation of hydrocarbons by Gif chemistry, we have, in the first part of this paper, studied the mechanism of the lipoxygenase enzymes using soybean lipoxygenase as a model. Hydrocarbons 49-61 linoleate 9S-lipoxygenase-4 Glycine max 151-163 7870345-10 1994 Chronic hydrocarbon exposure scores and relative interstitial volume in the renal cortex at the time of renal biopsy was significantly higher in GP 1 than GP 2 (P < 0.001). Hydrocarbons 8-19 GTP binding protein 1 Homo sapiens 145-149 8125016-4 1994 This mapping data should prove useful in determining the role that the AHR locus plays in human cancer incidence and in the identification of human populations with altered susceptibilities to the toxic/carcinogenic effects of planar aromatic hydrocarbons. Hydrocarbons 243-255 aryl hydrocarbon receptor Homo sapiens 71-74 8120057-2 1994 The gene for cytochrome P4501A2 is constitutively expressed in the liver of vertebrates and shows induced expression when an organism is exposed to polycyclic aromatic hydrocarbons and halogenated hydrocarbons. Hydrocarbons 168-180 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 13-31 8262901-2 1993 Two different binding modes were considered, i.e., the respective hydrocarbon chains of 1- and 2-lauroyl fatty acid esters were located at the PLA2 binding sites usually observed in the complex crystals (Form A2) and at the reverse sites (Form A1). Hydrocarbons 66-77 LOC104974671 Bos taurus 143-147 8303708-8 1993 The results indicate that the suppression of the TNP-LPS-mediated immune response may be a more reliable indicator of the Ah receptor-dependent immunotoxicity of halogenated hydrocarbons. Hydrocarbons 174-186 aryl-hydrocarbon receptor Mus musculus 122-133 8246922-2 1993 The P-450s assessed included the polyaromatic hydrocarbon-inducible CYP1A1 and CYP1A2 systems, together with the phenobarbital-inducible P-450s, CYP2B1, CYP2B2, CYP3A1, which were examined 18 hr after a single intraperitoneal dose of the respective inducing agents. Hydrocarbons 46-57 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 68-74 8239313-7 1993 Addition of beta-amyloid peptide to bovine brain phospholipid membranes significantly changed the electron density associated with the hydrocarbon core. Hydrocarbons 135-146 amyloid beta precursor protein Homo sapiens 12-32 1390689-8 1992 In contrast, the hydrocarbon backbone did influence potency: cationic amphiphiles containing a steroid backbone were more potent inhibitors of PKC than their straight-chain analogues. Hydrocarbons 17-28 proline rich transmembrane protein 2 Homo sapiens 143-146 8466918-3 1993 Here we have examined the physicochemical characteristics of a fatty acid binding site of IRBP using a set of fluorescent fatty acid analogs with an anthracene moiety attached at different positions along the hydrocarbon chain. Hydrocarbons 209-220 retinol binding protein 3 Homo sapiens 90-94 8442004-1 1993 The cytochrome P4501 gene family consists of two members, CYP1A1 and CYP1A2, that are induced by halogenated hydrocarbons and polycyclic aromatic hydrocarbons. Hydrocarbons 109-121 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 58-64 8442004-1 1993 The cytochrome P4501 gene family consists of two members, CYP1A1 and CYP1A2, that are induced by halogenated hydrocarbons and polycyclic aromatic hydrocarbons. Hydrocarbons 109-121 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 69-75 1445921-6 1992 Moreover, Ca2+ binding weakened the hydrogen bonding of the polar head region of SGC and the hydrocarbon chains became more disordered as revealed by an increase in the correlation field splitting pressure of SGC. Hydrocarbons 93-104 carbonic anhydrase 2 Homo sapiens 10-13 1448801-0 1992 Factor VIII/von Willebrand factor levels in plasma frozen to-30 degrees C in air or halogenated hydrocarbons. Hydrocarbons 96-108 von Willebrand factor Homo sapiens 12-33 1390689-9 1992 Changing the nature of the hydrocarbon from a sterol to an alkyl group lowers the pK of the amine head group so that the straight-chain analogues are no longer cationic in the conditions in the PKC assay. Hydrocarbons 27-38 proline rich transmembrane protein 2 Homo sapiens 194-197 1535661-2 1992 Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3-chlorophenyl)piperazines for 5-HT1A receptor site. Hydrocarbons 14-25 5-hydroxytryptamine receptor 1A Homo sapiens 99-114 1535661-3 1992 The effect of the hydrocarbon chain of the model 4-substituted 1-(3-chlorophenyl)piperazines 12-31 on their affinity for 5-HT1A receptor sites was investigated. Hydrocarbons 18-29 5-hydroxytryptamine receptor 1A Homo sapiens 121-136 1640215-4 1992 Cytochrome P450 enzymes are involved in the metabolism of drugs, carcinogens, steroids, pesticides, hydrocarbons and natural products. Hydrocarbons 100-112 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 1413865-2 1992 Polychlorotrifluoroethylene (PCTFE) is a perhalogenated hydrocarbon which consists mainly of C-6 and C-8 oligomers of chlorotrifluoroethylene (CTFE) end-capped with chlorine and referred to as trimer and tetramer, respectively. Hydrocarbons 56-67 complement C6 Rattus norvegicus 93-96 1381668-0 1992 Differential expression of basal and hydrocarbon-induced cytochrome P-450 monooxygenase and quinone reductase activities in subpopulations of murine epidermal cells differing in their stages of differentiation. Hydrocarbons 37-48 cytochrome P450, family 20, subfamily a, polypeptide 1 Mus musculus 57-87 1381668-0 1992 Differential expression of basal and hydrocarbon-induced cytochrome P-450 monooxygenase and quinone reductase activities in subpopulations of murine epidermal cells differing in their stages of differentiation. Hydrocarbons 37-48 crystallin, zeta Mus musculus 92-109 1553751-2 1992 In all cases, PLA2 activation, measured as the appearance of lysophosphatidylethanolamine, preceded the release of lactic dehydrogenase during incubation of the cells at 37 degrees C. It is concluded that for these halogenated hydrocarbons phospholipase A2 activation may be part of the chain of causality leading from initial bioactivation to ultimate cell death. Hydrocarbons 227-239 phospholipase A2 group IB Rattus norvegicus 14-18 1374249-4 1992 Using purified isoenzymes in an enzyme-linked immunosorbent assay it was found that the affinity of binding to the two rabbit hydrocarbon-inducible isoenzymes is reduced compared with that for rat CYP1A1. Hydrocarbons 126-137 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 197-203 1566044-4 1992 Alkenes from microalgae, such as n-C21:6, n-C17:1 and unusual C25 and C30 isoprenoid alkenes, are often the most abundant single components in sedimentary hydrocarbon distributions. Hydrocarbons 155-166 TBL1X/Y related 1 Homo sapiens 35-38 1566044-4 1992 Alkenes from microalgae, such as n-C21:6, n-C17:1 and unusual C25 and C30 isoprenoid alkenes, are often the most abundant single components in sedimentary hydrocarbon distributions. Hydrocarbons 155-166 cytokine like 1 Homo sapiens 44-47 1934996-4 1991 The communities are situated in the centre of the recent exploration for hydrocarbon resources in the Beaufort Sea and have experienced the direct social impacts of this industrial activity. Hydrocarbons 73-84 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 111-114 1503644-2 1992 Recent studies (Nair RV, et al., Chem Res Toxicol 4:115-122, 1991) in our laboratory have revealed both deoxyguanosine (dGuo) and deoxyadenosine (dAdo) adducts formed from the anti- and syn-diol epoxides of DB[a,j]A in cultured mouse epidermal cells after exposure to this hydrocarbon. Hydrocarbons 273-284 joined toes Mus musculus 186-189 1531693-4 1992 Electron density profiles calculated from the X-ray diffraction data showed that the time-averaged locations for the DHPs and cholesterol in the membrane overlap, leading to the conclusion that the addition of cholesterol alters the lipid bilayer hydrocarbon core structure in a manner that makes drug partitioning into the membrane less energetically favorable. Hydrocarbons 247-258 deoxyhypusine synthase Homo sapiens 117-121 1924354-4 1991 Gel-permeation chromatography of [3H]mevalonate-labeled hydrocarbons released from immunoprecipitated ras proteins overexpressed in COS cells indicated that Ha-ras p21(Leu-189) was also a substrate for 20-carbon isoprenyl modification in vivo. Hydrocarbons 56-68 H3 histone pseudogene 16 Homo sapiens 164-167 1765414-5 1991 The only parameter that was significantly influenced by hydrocarbon exposure was the urinary activity of beta-N-acetylglucosaminidase. Hydrocarbons 56-67 O-GlcNAcase Homo sapiens 105-133 1797945-3 1991 One conformation, shown by sn-1-18:0 DGs containing an sn-2 22:6(n-3)-, 20:4(n-6)-, or 20:3(n-9)- group, determines a regular packing that resembles a known hybrid subcell, HS2, of crystalline hydrocarbon chains. Hydrocarbons 193-204 spectrin beta, erythrocytic Homo sapiens 173-176 1854730-6 1991 The initial decrease in Tm (delta H or delta S) with increasing values of delta C/CL is attributed to the progressive increase in the magnitude of the chain-terminal perturbations on the conformational statistics of the adjacent hydrocarbon chains and hence the lateral chain-chain interactions of these mixed-chain phosphatidylcholines in the gel-state bilayer. Hydrocarbons 229-240 crystallin gamma C Homo sapiens 80-84 1941434-4 1991 It was found that increased binding of CsA paralleled the increased ordering of hydrocarbon chains achieved by addition of cholesterol to these liposomes. Hydrocarbons 80-91 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 39-42 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Hydrocarbons 46-58 Rac family small GTPase 1 Homo sapiens 77-81 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Hydrocarbons 46-58 Rac family small GTPase 2 Homo sapiens 83-87 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Hydrocarbons 46-58 RAS like proto-oncogene A Homo sapiens 93-97 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Hydrocarbons 46-58 Rac family small GTPase 1 Homo sapiens 77-80 2021617-2 1991 On the basis of a limited set of published surface areas, we previously proposed that heat capacity changes (delta C degrees p) for the transfer of hydrocarbons from water to the pure liquid phase and for the folding of globular proteins exhibit the same proportionality to the reduction in water-accessible nonpolar surface area (delta Anp) [Spolar, R.S., Ha, J.H., & Record, M.T., Jr. (1989) Proc. Hydrocarbons 148-160 natriuretic peptide A Homo sapiens 337-340 1941434-7 1991 In DMPG liposomes, CsA was found in hydrocarbon chains adjacent to the polar head group, while in liposomes prepared from phosphatidylglycerol containing mixed fatty acids, CsA was associated with the polar head group region without penetrating the hydrocarbon chains of phosphatidylglycerol. Hydrocarbons 36-47 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 19-22 2038753-0 1991 Induction of differentiation in human myeloblastic leukemia ML-1 cells by heptachlor, a chlorinated hydrocarbon insecticide. Hydrocarbons 100-111 interleukin 17F Homo sapiens 60-64 1913974-4 1991 DDH exhibited a remarkable regiospecificity of enzymatic catalysis with regard to the site of the dihydrodiol moiety of the parent hydrocarbon. Hydrocarbons 131-142 dihydrodiol dehydrogenase Rattus norvegicus 0-3 1692256-9 1990 Our observations indicate that, although AHH induction was genetically determined in each strain, activity can be induced in hepatocytes of so-called nonresponsive as well as responsive mouse strains by treatment with aromatic hydrocarbons after transfer of the cells to primary culture. Hydrocarbons 227-239 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 41-44 1796113-3 1991 Leading noxa in the production of high-octane aviation benzine (production "sulfur acidic alkylation", are the sulphur containing organic compounds, hydrogen sulphide, and in some working places--hydrocarbons (benzine and aromatic); in the production of "Ethylene" and "Polypropylene" leading noxae are the saturated hydrocarbons, and the sulphur-containing organic compounds as well as the unsaturated hydrocarbons (ethylene and propylene). Hydrocarbons 196-208 phorbol-12-myristate-13-acetate-induced protein 1 Homo sapiens 8-12 2247082-0 1990 Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing. Hydrocarbons 5-16 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 34-51 2260059-2 1990 A new type of ski wax has recently been introduced, a powder consisting of low-molecular perfluorinated hydrocarbons. Hydrocarbons 104-116 SKI proto-oncogene Homo sapiens 14-17 2170048-1 1990 A sample of amosite asbestos was modified by effectively adding C8 and C18 hydrocarbon chains to the fibre surfaces. Hydrocarbons 75-86 Bardet-Biedl syndrome 9 Homo sapiens 71-74 2257126-0 1990 Numerical simulation of the thermal destruction of some chlorinated C1 and C2 hydrocarbons. Hydrocarbons 78-90 heterogeneous nuclear ribonucleoprotein C Homo sapiens 68-77 2121922-3 1990 Unlike normal, sexually mature males, three day old ap4/ap4 males synthesize courtship-stimulating hydrocarbons that immature males make; as a result they elicit vigorous courtship (Jallon and Hotta, 1979; Jallon et al., 1986). Hydrocarbons 99-111 cropped Drosophila melanogaster 52-59 2306261-3 1990 Following treatment with hydrocarbons such as 3-methylcholanthrene (MC) and isosafrole (ISF) both cytochromes P450c (P450IA1) and P450d (P450IA2) are also induced in rat liver. Hydrocarbons 25-37 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 110-115 2225238-2 1990 The alkali metal cations remained in the aqueous phase yet specifically influenced the transport of Ca2+ into the hydrocarbon solvent. Hydrocarbons 114-125 carbonic anhydrase 2 Homo sapiens 100-103 2322316-4 1990 Hydrocarbon generation from amino acids was inhibited by hydroxyl radical scavengers, but catalase and superoxide dismutase were more efficient. Hydrocarbons 0-11 catalase Homo sapiens 90-98 2193978-1 1990 The Isoparaffins covered in this manuscript are branched aliphatic hydrocarbons with a carbon skeleton length ranging from approximately C10 to C15. Hydrocarbons 67-79 homeobox C10 Homo sapiens 137-140 2193978-1 1990 The Isoparaffins covered in this manuscript are branched aliphatic hydrocarbons with a carbon skeleton length ranging from approximately C10 to C15. Hydrocarbons 67-79 placenta associated 8 Homo sapiens 144-147 25699544-9 2015 An enriched abundance of alkB genes was observed during the degradation of saturated hydrocarbons. Hydrocarbons 85-97 alkB homolog 1, histone H2A dioxygenase Homo sapiens 25-29 2314153-0 1990 Binding of thiopental to human serum albumin in the presence of halogenated hydrocarbons and ethers. Hydrocarbons 76-88 albumin Homo sapiens 31-44 2296774-2 1990 Subchronic studies with CCl4 demonstrated that this chlorinated hydrocarbon markedly suppressed T-dependent antibody responses following 7 consecutive days of administration at doses between 500 and 5000 mg/kg. Hydrocarbons 64-75 chemokine (C-C motif) ligand 4 Mus musculus 24-28 33815647-3 2020 Results obtained by flowing hydrocarbons (CH4 and CH3CHCH2) unequivocally show that these gases react with surface hydroxyl groups to produce water without producing carbon oxides and release electrons that localize on Sn to eventually form SnO. Hydrocarbons 28-40 strawberry notch homolog 1 Homo sapiens 241-244 2097282-0 1990 [Specificity of cytochrome P-450 forms in the rat liver after inhalation of multicomponent hydrocarbon mixture]. Hydrocarbons 91-102 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 16-32 2343089-4 1990 However, a hint at the group of halogenated hydrocarbons is only possible, if additional information about miscibility with water is accessible. Hydrocarbons 44-56 histidine triad nucleotide binding protein 1 Homo sapiens 11-15 6210189-1 1984 The Aryl hydrocarbon hydroxylase (AHH) activity in the lavaged PAMs was investigated in male Fischer rats after inhalation of diluted diesel exhaust (DE), and compared with intratracheal instillation of the organic solvent extract of hydrocarbons adsorbed on the particulate surface. Hydrocarbons 234-246 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 34-37 33031985-15 2021 The subsequent exposure to CPF reverses AR, suggesting a complex interaction of different pollutants in contaminated environments, WAF hydrocarbons alter liver metabolism by inducing the expression of LXR, GR, antioxidant and detoxifying enzymes, and both inflammatory and anti-inflammatory cytokines, and causing mild hepatic steatosis. Hydrocarbons 135-147 oxysterols receptor LXR-alpha Oncorhynchus mykiss 201-204 33031985-15 2021 The subsequent exposure to CPF reverses AR, suggesting a complex interaction of different pollutants in contaminated environments, WAF hydrocarbons alter liver metabolism by inducing the expression of LXR, GR, antioxidant and detoxifying enzymes, and both inflammatory and anti-inflammatory cytokines, and causing mild hepatic steatosis. Hydrocarbons 135-147 glucocorticoid receptor Oncorhynchus mykiss 206-208 31139154-11 2019 Raman spectra indicated that aliphatic hydrocarbons increased in soil during nitrification, and these compounds probably bind to NO3 to form biogenic nitrate. Hydrocarbons 39-51 NBL1, DAN family BMP antagonist Homo sapiens 129-132 34899644-6 2021 The major hydrocarbon family genes and Carbohydrate Active Enzyme pathways were predicted to be highest in DJ04 with elevated concentrations of HCO3 and TOC. Hydrocarbons 10-21 rhomboid 5 homolog 2 Homo sapiens 153-156 34782267-4 2022 It was also concluded that the ratio of Raman intensities at the maximum of the peak of the symmetric CD2 stretching and at a maximum near 2168 cm-1 reflects the conformational order of the hydrocarbon chain and can be used for an evaluation of the fraction of the all-trans sequences. Hydrocarbons 190-201 CD2 molecule Homo sapiens 102-105 34662568-3 2022 For chain segments at the beginning of the hydrocarbon region, (alpha2)-values are markedly restricted and temperature independent in DPPC with the lowest water content, whereas they increase with temperature in the low and fully hydrated bilayers, particularly at the highest temperatures. Hydrocarbons 43-54 glycoprotein hormone subunit alpha 2 Homo sapiens 64-70 34710761-2 2022 However, HAp has emerged as a very promising adsorbent for sequestering contaminants like heavy metals, dyes, hydrocarbons as well as other emerging pollutants from wastewater as a result of its versatility and encouraging adsorptive properties. Hydrocarbons 110-122 reticulon 3 Homo sapiens 9-12 34881893-4 2021 Here, we carry out systematic conformational sampling and ISC rate calculations on 3(RO OR") clusters formed in the recombination reactions of different diastereomers of the first-generation peroxyl radicals originating in both OH- and NO3-initiated reactions of alpha-pinene, a key biogenic hydrocarbon for atmospheric aerosol formation. Hydrocarbons 294-305 NBL1, DAN family BMP antagonist Homo sapiens 238-241 34955897-15 2021 We also discuss the implication of fish intestinal ABC proteins in the transport of physiological substrates and aquatic pollutants, such as pesticides, cyanotoxins, metals, hydrocarbons, and pharmaceutical products. Hydrocarbons 174-186 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 51-54 1447747-3 1992 Unlike analogs bearing hydrocarbon substituents at C-4, the resulting dihydropyridinium metabolite did not undergo further oxidation to the pyridinium compound but rather underwent hydrolytic cleavage. Hydrocarbons 23-34 complement C4A (Rodgers blood group) Homo sapiens 51-54 34929595-3 2022 The hydrogen content in the gas stream was about 26 vol% at 600 oC for non-catalytic pyrolysis, which increased to around 55 vol% at the expense of light hydrocarbons such as methane and C2-4 for the catalytic process with the biochar/mask ratio of 3. Hydrocarbons 154-166 complement C2 Homo sapiens 187-191 34610558-4 2022 Furthermore, and at a similar operating temperature; the diesel range hydrocarbons (C10-C19) were around 66% of the total fuel like chromatograph studied for the pyrolysis oils. Hydrocarbons 70-82 homeobox C10 Homo sapiens 84-87 34889092-6 2021 The PCB2-b-PSB4 aggregate modulation efficiency of SBs associated with the intercharge hydrocarbon spacer length (CSL) rather than the symmetry with the SB in the PSB chain. Hydrocarbons 87-98 chorionic somatomammotropin hormone like 1 Homo sapiens 114-117 34833229-6 2021 We have shown that oligomerization of ethylene in alpha-olefin reaction media proceeds faster than in saturated hydrocarbons, providing the formation of 1-hexene, 1-octene, and branched C10 and C12 olefins; the composition and the ratio of the reaction products depended on the nature of PNP ligand. Hydrocarbons 112-124 chromosome 12 open reading frame 57 Homo sapiens 186-189 34822896-5 2022 Results show that long-chain hydrocarbons in PS-1 are adsorbed on the non-polar region of UC by Van der Waals force, while -COOH groups in PS-1 are adsorbed on the polar sites of -COOH and -OH of UC by hydrogen bonds. Hydrocarbons 29-41 presenilin 1 Homo sapiens 45-49 34822896-5 2022 Results show that long-chain hydrocarbons in PS-1 are adsorbed on the non-polar region of UC by Van der Waals force, while -COOH groups in PS-1 are adsorbed on the polar sites of -COOH and -OH of UC by hydrogen bonds. Hydrocarbons 29-41 presenilin 1 Homo sapiens 139-143 34822896-6 2022 The synergistic effect of long-chain hydrocarbons and -COOH groups in PS-1 improves the hydrophobicity of the UC surface. Hydrocarbons 37-49 presenilin 1 Homo sapiens 70-74 34833229-8 2021 Due to branched character of C10+ hydrocarbons, formed during oligomerization of ethylene, resulting polyolefins demonstrate higher low-temperature DR efficiency at low polymer concentrations (~1 ppm) in comparison with benchmark polymers prepared from the mixtures of linear alpha-olefins and from pure 1-hexene. Hydrocarbons 34-46 chromosome 12 open reading frame 57 Homo sapiens 29-32 34171587-4 2021 Air pollutants (particulate matter, oxygen radicals, hydrocarbons and volatile organic compounds) and water pollutants (metals and organic chemicals) can also intensify Th1/Th17 immune response and could exacerbate SARS-CoV-2 related respiratory distress and failure. Hydrocarbons 53-65 negative elongation factor complex member C/D Homo sapiens 169-172 34510595-7 2021 Moreover, it is identified that nanoscale molecular fouling of the graphene surface during gas separation where graphene pores are partially blocked by hydrocarbon contaminants under experimental conditions, controls both selectivity and temperature dependent permeance. Hydrocarbons 152-163 gastrin Homo sapiens 91-94 34590479-2 2021 The conformation of flexible hydrocarbon chains bearing contiguous methyl substituents is controlled through the avoidance of syn-pentane interactions: alternating syn-anti isomers adopt a linear conformation while all-syn isomers adopt a helical conformation. Hydrocarbons 29-40 synemin Homo sapiens 126-129 34590479-2 2021 The conformation of flexible hydrocarbon chains bearing contiguous methyl substituents is controlled through the avoidance of syn-pentane interactions: alternating syn-anti isomers adopt a linear conformation while all-syn isomers adopt a helical conformation. Hydrocarbons 29-40 synemin Homo sapiens 164-167 34590479-2 2021 The conformation of flexible hydrocarbon chains bearing contiguous methyl substituents is controlled through the avoidance of syn-pentane interactions: alternating syn-anti isomers adopt a linear conformation while all-syn isomers adopt a helical conformation. Hydrocarbons 29-40 synemin Homo sapiens 219-222 34590479-5 2021 Surprisingly, when the methyl substituents of alternating syn-anti hydrocarbons are replaced with acetoxyethyl groups, the main chain of almost 95% of the population of molecules adopt a linear conformation. Hydrocarbons 67-79 synemin Homo sapiens 58-61 34383986-3 2021 syn -IDBF possesses a high degree of paratropicity, exceeding that of the parent hydrocarbon, which in turn results in strong diradical character for syn -IIDBF. Hydrocarbons 81-92 synemin Homo sapiens 0-3 34383986-3 2021 syn -IDBF possesses a high degree of paratropicity, exceeding that of the parent hydrocarbon, which in turn results in strong diradical character for syn -IIDBF. Hydrocarbons 81-92 synemin Homo sapiens 150-153 34506131-3 2021 Our previous work has shown that hydrocarbon-stapled peptides targeted to the Beclin 1 coiled-coil domain reduced Beclin 1 homodimerization and promoted the Beclin 1-Atg14L/UVRAG interaction. Hydrocarbons 33-44 beclin 1 Homo sapiens 78-86 34324250-1 2021 Fast, cheap, and simple separation of lipids and hydrocarbons can currently be achieved using thin-layer chromatography. Hydrocarbons 49-61 Fas activated serine/threonine kinase Homo sapiens 0-4 34378990-12 2021 Understanding how cold-adapted microbiomes catalyze hydrocarbon degradation at low in situ temperature is crucial in the Labrador Sea, which remains relatively cold throughout the year. Hydrocarbons 52-63 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 130-133 34506131-3 2021 Our previous work has shown that hydrocarbon-stapled peptides targeted to the Beclin 1 coiled-coil domain reduced Beclin 1 homodimerization and promoted the Beclin 1-Atg14L/UVRAG interaction. Hydrocarbons 33-44 beclin 1 Homo sapiens 114-122 34506131-3 2021 Our previous work has shown that hydrocarbon-stapled peptides targeted to the Beclin 1 coiled-coil domain reduced Beclin 1 homodimerization and promoted the Beclin 1-Atg14L/UVRAG interaction. Hydrocarbons 33-44 beclin 1 Homo sapiens 157-165 34506131-3 2021 Our previous work has shown that hydrocarbon-stapled peptides targeted to the Beclin 1 coiled-coil domain reduced Beclin 1 homodimerization and promoted the Beclin 1-Atg14L/UVRAG interaction. Hydrocarbons 33-44 autophagy related 14 Homo sapiens 166-172 34506131-3 2021 Our previous work has shown that hydrocarbon-stapled peptides targeted to the Beclin 1 coiled-coil domain reduced Beclin 1 homodimerization and promoted the Beclin 1-Atg14L/UVRAG interaction. Hydrocarbons 33-44 UV radiation resistance associated Homo sapiens 173-178 34506131-6 2021 Placing the hydrocarbon staple closer to the Beclin 1-peptide interface enhanced their binding affinity by ~10- to 30-fold. Hydrocarbons 12-23 beclin 1 Homo sapiens 45-53 34341770-4 2021 The hydrocarbon/water interfaces are functionalized with a secondary antibody of IgG protein and SARS-CoV-2 spike receptor binding domain (RBD), to produce two different Janus emulsions. Hydrocarbons 4-15 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 108-113 34324831-6 2021 Incorporating purified IR into alkyl maltoside micelles with increasing hydrocarbon lengths also increased IR activity, but more modestly than by increasing lipid acyl chain length in cells. Hydrocarbons 72-83 insulin receptor Homo sapiens 23-25 34324831-6 2021 Incorporating purified IR into alkyl maltoside micelles with increasing hydrocarbon lengths also increased IR activity, but more modestly than by increasing lipid acyl chain length in cells. Hydrocarbons 72-83 insulin receptor Homo sapiens 107-109 34160136-0 2021 Ir(III)-Catalyzed Diarylation/Annulation of Benzoic Acids: Facile Access to Multi-Aryl Spirobifluorenes as Pure Hydrocarbon Hosts for High-Performance OLEDs. Hydrocarbons 112-123 insulin receptor Homo sapiens 0-7 34533180-1 2021 Nanoparticles (NPs) of Pd1--xGax (x = 0.67, 0.5, 0.33), stabilized in non-aqueous colloidal solution, were obtained via an organometallic approach under mild conditions using (Pd2(dvds)3) and GaCp* as all-hydrocarbon ligated metal-precursor compounds (dvds = 1,1,3,3-tetramethyl-1,3-divinyl-disiloxane; Cp* = eta5-C5Me5; Me = CH3). Hydrocarbons 205-216 glutaminase Homo sapiens 192-196 34189811-11 2021 It is demonstrated that Al and Sn can be incorporated into the FDP zeolite framework to produce active and selective methanol-to-hydrocarbon and glucose isomerization catalysts, respectively. Hydrocarbons 129-140 otoraplin Homo sapiens 63-66 34388318-6 2021 One of the most important features of the ALEX2 test system is that unique allergen molecules and allergenic extracts are included in its composition, and a method has been found to inhibit cross-reactive hydrocarbon determinants (CCDs), which cause frequent non-specific binding of IgE-aT. Hydrocarbons 205-216 armadillo repeat containing X-linked 2 Homo sapiens 42-47 34270894-2 2021 Large spin-orbit coupling (SOC) is difficult to achieve in simple hydrocarbon structures limiting the intersystem crossing (ISC) rates. Hydrocarbons 66-77 spindlin 1 Homo sapiens 6-10 34458835-5 2021 Here we report the development of two hydrocarbon stapled peptides, CSTAD5 and CSTAD6, that are cell permeable and bind PKC to disrupt PKC-gravin complex formation in cells. Hydrocarbons 38-49 proline rich transmembrane protein 2 Homo sapiens 120-123 34458835-5 2021 Here we report the development of two hydrocarbon stapled peptides, CSTAD5 and CSTAD6, that are cell permeable and bind PKC to disrupt PKC-gravin complex formation in cells. Hydrocarbons 38-49 proline rich transmembrane protein 2 Homo sapiens 135-138 35562375-4 2022 Here, we use carbon isotope and PVT data from co-produced hydrocarbon gas and liquid to provide evidence for widespread migration of gas-condensate in the Montney unconventional petroleum system of western Canada. Hydrocarbons 58-69 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 70-73 34069753-3 2021 In this study, we investigate i,i + 1 hydrocarbon stapling between cis-4-allyloxy-l-proline and various olefin-tethered amino acids. Hydrocarbons 38-49 suppressor of cytokine signaling 6 Homo sapiens 67-72 35635879-7 2022 Among the low-molecular-weight alkanes either even numbered autochthonous alkanes n-C16, C18, C22, arising during the microbial transformation of aliphatic hydrocarbons, or n-C17, indicating the inclusion of phyto- and zooplankton alkanes, prevailed. Hydrocarbons 156-168 Bardet-Biedl syndrome 9 Homo sapiens 89-92 34231583-5 2021 In pyrolysis experiments, up to 49 species were detected and identified in the gas-phase, including reactive intermediates and isomeric/isobaric hydrocarbons, oxygenated species as well as aluminium containing molecules. Hydrocarbons 145-157 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 79-82 34257463-0 2021 Pure hydrocarbon cycles in TMC-1: Discovery of ethynyl cyclopropenylidene, cyclopentadiene and indene. Hydrocarbons 5-16 transmembrane channel like 1 Homo sapiens 27-32 34257463-1 2021 We report the detection for the first time in space of three new pure hydrocarbon cycles in TMC-1: c-C3HCCH (ethynyl cyclopropenylidene), c-C5H6 (cyclopentadiene) and c-C9H8 (indene). Hydrocarbons 70-81 transmembrane channel like 1 Homo sapiens 92-97 35562375-4 2022 Here, we use carbon isotope and PVT data from co-produced hydrocarbon gas and liquid to provide evidence for widespread migration of gas-condensate in the Montney unconventional petroleum system of western Canada. Hydrocarbons 58-69 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 133-136 35562375-7 2022 The combined convex upward and increasing or uniform isotopic signatures are interpreted as mixing profiles formed by the introduction of high-maturity gas-condensate (C1-C15) to shallower zones with in-situ hydrocarbon fluids of lower thermal maturity. Hydrocarbons 208-219 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 152-155 35562375-8 2022 The recognition of widespread gas-condensate migration adds to the complex history of internal hydrocarbon migration within the Montney tight-petroleum system including previously identified migration episodes of early oil and late-stage methane-rich gas. Hydrocarbons 95-106 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 30-33 35562375-8 2022 The recognition of widespread gas-condensate migration adds to the complex history of internal hydrocarbon migration within the Montney tight-petroleum system including previously identified migration episodes of early oil and late-stage methane-rich gas. Hydrocarbons 95-106 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 251-254 35601311-2 2022 For hydrocarbon cracking, the industrial catalyst is an important parameter in reaction technology to produce valuable compounds, e.g., light olefins (C3-C5) and gasoline from crude oil fractions with high molecular weight (C16+). Hydrocarbons 4-15 ADAM metallopeptidase with thrombospondin type 1 motif 1 Homo sapiens 151-156 35404590-1 2022 Hydraulic fracturing of unconventional oil/gas shales has changed the energy landscape of the U.S. Recovery of hydrocarbons from tight, hydraulically fractured shales is a highly inefficient process, with estimated recoveries of <25% for natural gas and <5% for oil. Hydrocarbons 111-123 gastrin Homo sapiens 43-46 35404590-1 2022 Hydraulic fracturing of unconventional oil/gas shales has changed the energy landscape of the U.S. Recovery of hydrocarbons from tight, hydraulically fractured shales is a highly inefficient process, with estimated recoveries of <25% for natural gas and <5% for oil. Hydrocarbons 111-123 gastrin Homo sapiens 246-249 35449939-5 2022 In situ DRIFTS shows that C2H4 is adsorbed on the Mn3Ce3/NAC catalysts to generate hydrocarbon activated intermediates, R-COOH, and the reaction mechanism followed the E-R mechanism. Hydrocarbons 83-94 synuclein alpha Homo sapiens 57-60 35394270-6 2022 With the temperature increased from low to high during CS/WP pyrolysis, the primary sequential response of VOCs (acids phenols/esters alcohols/ethers/aldehydes/ketones hydrocarbons/aromatics) corresponded to the RFG response (hydroxyl groups -CH3/-CH2-/-CH groups aliphatic ethers and conjugated ketones). Hydrocarbons 174-186 citrate synthase Homo sapiens 55-60 35392167-12 2022 The increase in the number of PlsEtns with p16:1/20:4 and p16:1/22:6 suggested that 20:4 and 22:6, the main fatty acids at the sn-2 position in the rat lymphatic plasmalogen, were preferentially re-esterified at the sn-2 position, regardless of the types of hydrocarbon chains at the sn-1 position. Hydrocarbons 258-269 cyclin-dependent kinase inhibitor 2A Rattus norvegicus 43-46 35392167-12 2022 The increase in the number of PlsEtns with p16:1/20:4 and p16:1/22:6 suggested that 20:4 and 22:6, the main fatty acids at the sn-2 position in the rat lymphatic plasmalogen, were preferentially re-esterified at the sn-2 position, regardless of the types of hydrocarbon chains at the sn-1 position. Hydrocarbons 258-269 cyclin-dependent kinase inhibitor 2A Rattus norvegicus 58-61 35313055-5 2022 The gas adsorption behavior of this flexible MOF was evaluated, and the selective separation of light hydrocarbons and Freon gases is achieved. Hydrocarbons 102-114 gastrin Homo sapiens 4-7 35314750-4 2022 Soils adjacent to working well oils indicated new petroleum input with higher ratio of low to high molecular weight (LMW/HMW) hydrocarbons. Hydrocarbons 126-138 cilia and flagella associated protein 97 Homo sapiens 121-124 35113511-4 2022 The fluorine-free waterborne hydroxyl acrylic resin (HAR) emulsion containing long hydrocarbon chains endowed the electrospun polyacrylonitrile/blocked isocyanate prepolymer (PAN/BIP) fibrous membranes with superior hydrophobicity; meanwhile, crosslinking agent BIP ensured strong chemical binding between hydrocarbon segments and fiber substrate. Hydrocarbons 83-94 lymphatic vessel endothelial hyaluronan receptor 1 Homo sapiens 53-56 35322233-4 2022 Here we designed a hydrocarbon-stapled peptide that specifically disrupts Ca2+-triggered membrane fusion by interfering with the so-called primary interface between the neuronal SNARE complex and the Ca2+-binding C2B domain of synaptotagmin-1. Hydrocarbons 19-30 synaptotagmin I Mus musculus 227-242 35113511-4 2022 The fluorine-free waterborne hydroxyl acrylic resin (HAR) emulsion containing long hydrocarbon chains endowed the electrospun polyacrylonitrile/blocked isocyanate prepolymer (PAN/BIP) fibrous membranes with superior hydrophobicity; meanwhile, crosslinking agent BIP ensured strong chemical binding between hydrocarbon segments and fiber substrate. Hydrocarbons 83-94 heat shock protein family A (Hsp70) member 5 Homo sapiens 262-265 35113511-4 2022 The fluorine-free waterborne hydroxyl acrylic resin (HAR) emulsion containing long hydrocarbon chains endowed the electrospun polyacrylonitrile/blocked isocyanate prepolymer (PAN/BIP) fibrous membranes with superior hydrophobicity; meanwhile, crosslinking agent BIP ensured strong chemical binding between hydrocarbon segments and fiber substrate. Hydrocarbons 306-317 lymphatic vessel endothelial hyaluronan receptor 1 Homo sapiens 53-56 35113511-4 2022 The fluorine-free waterborne hydroxyl acrylic resin (HAR) emulsion containing long hydrocarbon chains endowed the electrospun polyacrylonitrile/blocked isocyanate prepolymer (PAN/BIP) fibrous membranes with superior hydrophobicity; meanwhile, crosslinking agent BIP ensured strong chemical binding between hydrocarbon segments and fiber substrate. Hydrocarbons 306-317 heat shock protein family A (Hsp70) member 5 Homo sapiens 179-182 34985252-0 2022 Steering Hydrocarbon Selectivity in CO2 Electroreduction over Soft-Landed CuOx Nanoparticle-Functionalized Gas Diffusion Electrodes. Hydrocarbons 9-20 gastrin Homo sapiens 107-110 35195699-13 2022 Among workers, the prevalence of newly detected hypertension was elevated in all quintiles (Q) of cumulative total hydrocarbons above the first quintile (PR for Q3, 1.29 (95% CI, 1.13-1.46), PR for Q4, 1.25 (95% CI, 1.10-1.43), and PR for Q5, 1.31 (95% CI, 1.15-1.50)). Hydrocarbons 115-127 transmembrane protein 37 Homo sapiens 154-156 2628054-0 1989 Species differences in specificity of hydrocarbon-inducible forms of cytochrome P-450. Hydrocarbons 38-49 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 69-85 2585547-5 1989 These results indicate that PLP was incorporated into the bilayers and had a disordering effect on the hydrocarbon chains but did not extend into the spaces between bilayers. Hydrocarbons 103-114 proteolipid protein 1 Homo sapiens 28-31 2509067-9 1989 The correlation of 7,8-diol formation with phenacetin O-deethylation in a set of liver samples and the partial inhibition of the reaction by 7,8-benzoflavone and anti-rat P-450 beta NF-B suggest that the enzyme involved may be P1-450, the human ortholog of rat P-450 beta NF-B, which catalyzes both the formation of B(a)P-7,8-diol and its subsequent oxidation in tissues of polycyclic hydrocarbon-treated rats. Hydrocarbons 385-396 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 227-233 2586490-5 1989 When a homologous series of 5,8-dideazafolic acid analogs with hydrocarbon substituents on the 10-nitrogen were studied, these substituents were found to diminish the efficiency of utilization of these analogs as substrates for FPGS; this effect increased with increasing chain length of the hydrocarbon. Hydrocarbons 63-74 folylpolyglutamyl synthetase Mus musculus 228-232 2493985-12 1989 The hydrocarbon-modified deoxyribonucleosides were identified by comparison with standards of (+)-syn-BPDE-dGuo and (-)-anti-BPDE-dGuo. Hydrocarbons 4-15 joined toes Mus musculus 98-101 2706741-1 1989 Various chlorinated hydrocarbons, many of which are known hepatic tumor promoters, have been evaluated for their ability to stimulate protein kinase C (PKC) activity in vitro. Hydrocarbons 20-32 protein kinase C, gamma Rattus norvegicus 152-155 2752025-0 1989 Infrared and 31P-NMR studies of the interaction of Mg2+ with phosphatidylserines: effect of hydrocarbon chain unsaturation. Hydrocarbons 92-103 mucin 7, secreted Homo sapiens 51-54 3191575-11 1988 CPP is the first environmentally-relevant carcinogenic hydrocarbon found to be activated directly by peroxyl radical systems without prior biotransformation to a diol derivative by the cytochrome P-450 system. Hydrocarbons 55-66 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 185-201 2680378-0 1989 Radical intermediates in the cytochrome P-450-catalyzed oxidation of aliphatic hydrocarbons. Hydrocarbons 79-91 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 29-45 3143405-10 1988 The second stage appeared to involve penetration of PKC into the hydrocarbon region of the phospholipid. Hydrocarbons 65-76 proline rich transmembrane protein 2 Homo sapiens 52-55 3178886-0 1988 Antibodies to a synthetic peptide that react specifically with a common surface region on two hydrocarbon-inducible isoenzymes of cytochrome P-450 in the rat. Hydrocarbons 94-105 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 130-146 3178886-1 1988 An antibody that reacts with two hydrocarbon-inducible isoenzymes of rat cytochrome P-450 (c and d) in the rat was produced by immunising with a synthetic peptide, Leu-Ile-Ser-Lys-Phe-Gln-Lys-Leu-Met, which has the same primary structure as that of a region of both of these isoenzymes. Hydrocarbons 33-44 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 73-98 2837480-2 1988 We define membrane lipid fluidity to be T/eta, where eta is the viscosity of a long chain hydrocarbon reference solvent in which a fatty acid spin label gives the same EPR spectrum (quantitated by the order parameter S) as observed for the same probe in the membrane. Hydrocarbons 90-101 endothelin receptor type A Homo sapiens 42-45 3215961-0 1988 endo-1,4,5,6,7,7-hexachlorobicyclo[2.2.1]hept-5-ene-2-carboxylic acid, a superior resolving agent for the high-performance liquid chromatographic separation of enantiomers of hydroxylated derivatives of two azaaromatic hydrocarbons. Hydrocarbons 219-231 ENDO1 Homo sapiens 0-6 2837480-2 1988 We define membrane lipid fluidity to be T/eta, where eta is the viscosity of a long chain hydrocarbon reference solvent in which a fatty acid spin label gives the same EPR spectrum (quantitated by the order parameter S) as observed for the same probe in the membrane. Hydrocarbons 90-101 endothelin receptor type A Homo sapiens 53-56 2453947-1 1988 alpha 2u-Globulin, a protein of hepatic origin found in the urine of male rats, is accumulated in the kidney cortex during exposure to unleaded gasoline and has been implicated in the development of fuel hydrocarbon-induced nephropathy and renal neoplasia. Hydrocarbons 204-215 alpha2u globulin Rattus norvegicus 0-17 3178785-1 1988 Methanol, ethanol and isopropanol were tested for the ability to change effects of chlorinated hydrocarbons on the alanine aminotransferase (ALAT = GPT; EC 2.6.1.2.) Hydrocarbons 95-107 glutamic--pyruvic transaminase Rattus norvegicus 148-151 3377503-1 1988 A Mycobacterium sp., designated strain BG1, able to utilize the polycyclic aromatic hydrocarbon phenanthrene as the sole carbon and energy source was isolated from estuarine sediment following enrichment with the hydrocarbon. Hydrocarbons 84-95 acyl-CoA synthetase bubblegum family member 1 Homo sapiens 39-42 2854994-3 1988 In addition, cytochrome P-450 catalyzes reductive reactions, including a recently discovered reaction in which organic hydroperoxides are cleaved to yield hydrocarbons and aldehydes or ketones. Hydrocarbons 155-167 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 13-29 2447967-8 1987 Recently, we have characterized the partition step, demonstrating that DHPs reside, on a time-average basis, near the bilayer hydrocarbon core/water interface. Hydrocarbons 126-137 deoxyhypusine synthase Homo sapiens 71-75 3406035-0 1988 Role of cytochrome P-450 in hydrocarbon formation from xenobiotic and lipid hydroperoxides. Hydrocarbons 28-39 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 8-24 3118952-14 1987 For rhodopsin reconstituted in lipid bilayers, normal MII formation requires a well-adjusted fluidity of the hydrocarbon environment of the protein [Baldwin, P. A., & Hubbell, W. L. (1984) Biochemistry 24, 2633-2639], which was explained by an appropriate interfacial pressure at the protein-lipid interface. Hydrocarbons 109-120 rhodopsin Bos taurus 4-13 3587368-2 1987 Although formation of a benzo[a]pyrene (BaP) diol epoxide-deoxyguanosine adduct has been held responsible for biological activity, the more potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) binds extensively to deoxyadenosine residues in DNA, suggesting that hydrocarbon carcinogen-deoxyadenosine adducts may be instrumental in tumour initiation. Hydrocarbons 266-277 prohibitin 2 Homo sapiens 40-43 3629614-3 1987 Fractional AST release plateaued at 10-60 min following hydrocarbon exposure. Hydrocarbons 56-67 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 11-14 3103131-0 1987 Hydrocarbon formation in the reductive cleavage of hydroperoxides by cytochrome P-450. Hydrocarbons 0-11 cytochrome P-450 Oryctolagus cuniculus 69-85 3606384-6 1987 Hydrocarbons also caused extracellular release of the lysosomal enzymes cathepsin D (EC 3.4.23.5) and cathepsin B (EC 3.4.22.1) in a manner corresponding with cell damage. Hydrocarbons 0-12 cathepsin D Rattus norvegicus 72-83 3606384-6 1987 Hydrocarbons also caused extracellular release of the lysosomal enzymes cathepsin D (EC 3.4.23.5) and cathepsin B (EC 3.4.22.1) in a manner corresponding with cell damage. Hydrocarbons 0-12 cathepsin B Rattus norvegicus 102-113 3606384-8 1987 In addition, hydrocarbons also caused the release of cathepsin B and D from isolated lysosomes, and there was 10-15% more enzyme activity released in the culture medium of lysosomes exposed to concentrations of 0.5 and 1.0 mM compared to PAM cell cultures of either rats or rabbits. Hydrocarbons 13-25 cathepsin B Rattus norvegicus 53-64 2433367-8 1986 That activation-dependent hydrocarbons can be metabolized by S9 added to mammalian cell cultures resulting in the inhibition of viral IFN induction extends the capability and credibility for assessing suspect mutacarcinogens on this basis. Hydrocarbons 26-38 interferon alpha 1 Homo sapiens 134-137 2435747-3 1987 RPC-5 contains dichlorodifluoroethylene beads coated with a quaternary ammonium compound where the substituents are: R1 = methyl, and R2-4 = C8-10 hydrocarbons. Hydrocarbons 147-159 DNA-directed RNA polymerase core subunit RPC40 Saccharomyces cerevisiae S288C 0-5 3558585-2 1987 The Vydac C18 column resolved the phenols of each hydrocarbon with a wide range of retention times than the Zorbax ODS column. Hydrocarbons 50-61 Bardet-Biedl syndrome 9 Homo sapiens 10-13 3508432-1 1987 Hydrocarbon oxidation in the atmosphere proceeds generally by the following sequence of reactions: hydrocarbon + OH----alkyl radical + H2O, alkyl radical + O2 (3 sigma)----alkylperoxy radical, alkylperoxy radical + NO----alkoxy radical + NO2, alkoxy radical + O2 (3 sigma)----aldehyde + HO2. Hydrocarbons 0-11 heme oxygenase 2 Homo sapiens 287-290 3780743-7 1986 The rabbit enzyme metabolized the hydrocarbon with an apparent Vmax of 4 nmol nmol-1 min-1 and a Km of 8 microM, By contrast, phenobarbital-inducible P-450 LM2 or 3-methylcholanthrene-inducible P-450 LM4 from rabbit liver were quite ineffective catalysts of n-pentane metabolism. Hydrocarbons 34-45 cytochrome P450 2B4 Oryctolagus cuniculus 150-203 3742644-0 1986 The interaction of a homologous series of hydrocarbons with hepatic cytochrome P-450. Hydrocarbons 42-54 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 68-84 3742644-3 1986 Each of the 10 hydrocarbons produced a Type I spectral change, indicative of a low to high spin transition of the haem iron of cytochrome P-450. Hydrocarbons 15-27 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 127-143 3742644-9 1986 Taken collectively, our data show the importance of the hydrophobic and charge transfer characteristics of hydrocarbon substrates in dictating the position of the cytochrome P-450 spin equilibrium, and as such, provides a rational molecular explanation based on sound chemical principles for the differential interaction of hydrocarbons with cytochrome P-450. Hydrocarbons 107-118 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 163-179 3742644-9 1986 Taken collectively, our data show the importance of the hydrophobic and charge transfer characteristics of hydrocarbon substrates in dictating the position of the cytochrome P-450 spin equilibrium, and as such, provides a rational molecular explanation based on sound chemical principles for the differential interaction of hydrocarbons with cytochrome P-450. Hydrocarbons 107-118 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 342-358 3742644-9 1986 Taken collectively, our data show the importance of the hydrophobic and charge transfer characteristics of hydrocarbon substrates in dictating the position of the cytochrome P-450 spin equilibrium, and as such, provides a rational molecular explanation based on sound chemical principles for the differential interaction of hydrocarbons with cytochrome P-450. Hydrocarbons 324-336 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 163-179 3742644-9 1986 Taken collectively, our data show the importance of the hydrophobic and charge transfer characteristics of hydrocarbon substrates in dictating the position of the cytochrome P-450 spin equilibrium, and as such, provides a rational molecular explanation based on sound chemical principles for the differential interaction of hydrocarbons with cytochrome P-450. Hydrocarbons 324-336 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 342-358 3708089-8 1986 We demonstrate that strip-function models accurately define the positions of the C-2 carbons and thus the hydrocarbon thickness (dhc) of the bilayer. Hydrocarbons 106-117 complement C2 Homo sapiens 81-84 3824405-3 1986 The most potent mycotoxins (T-2, verrucarin A and roridin A) have acetyl side groups on, or a hydrocarbon chain between, carbons 4 and 15 of the basic ring structure. Hydrocarbons 94-105 brachyury 2 Rattus norvegicus 28-31 3080823-10 1986 Glutathione S-transferase was induced differentially by these hydrocarbons toward various substrates: toward 1-chloro-2,4-dinitrobenzene by benzene and toluene, toward 1,2-dichloro-4-nitrobenzene by benzene and xylenes, and no effect toward 1,2-epoxy-3-(p-nitrophenoxy)propane by any hydrocarbons. Hydrocarbons 284-296 hematopoietic prostaglandin D synthase Rattus norvegicus 0-25 3080823-10 1986 Glutathione S-transferase was induced differentially by these hydrocarbons toward various substrates: toward 1-chloro-2,4-dinitrobenzene by benzene and toluene, toward 1,2-dichloro-4-nitrobenzene by benzene and xylenes, and no effect toward 1,2-epoxy-3-(p-nitrophenoxy)propane by any hydrocarbons. Hydrocarbons 62-74 hematopoietic prostaglandin D synthase Rattus norvegicus 0-25 3942013-3 1986 A non-hepatotoxic dose of CCl4 did not cause a significant increase in ethane production except in PB-induced rats but did enhance n-pentane elimination, whereas an hepatotoxic dose increased the emission of both hydrocarbons. Hydrocarbons 213-225 C-C motif chemokine ligand 4 Rattus norvegicus 26-30 3830353-3 1985 It was observed that there was a good correlation between the increase in testosterone 7 alpha-hydroxylase by the halogenated hydrocarbons and their ability to cause body weight loss in the exposed rats. Hydrocarbons 126-138 cytochrome P450, family 2, subfamily a, polypeptide 1 Rattus norvegicus 74-106 4020577-3 1985 Hydrophobicity parameters have been calculated for hydrocarbon chains lying in the acyl and alkyl binding sites of human milk lipase. Hydrocarbons 51-62 carboxyl ester lipase Homo sapiens 121-132 3913777-5 1985 It was assumed that hydrocarbons were first converted to (omega-1)-alcohols by microsomal enzyme system and then to corresponding ketones by alcohol dehydrogenase. Hydrocarbons 20-32 aldo-keto reductase family 1, member A1 (aldehyde reductase) Mus musculus 141-162 4008473-9 1985 The results show that rabbit colon microsomes contain catalytically different cytochrome P-450, one of which is specialized for the omega-oxidation prostaglandins, the others being involved in the metabolism of exogenous compounds such as drugs and polycyclic hydrocarbons. Hydrocarbons 260-272 cytochrome P-450 Oryctolagus cuniculus 78-94 3838686-4 1985 The fluorescence anisotropy decay of 1,6-diphenyl-1,3,5-hexatriene in the hydrocarbon region indicated that the free volume of molecular rotation became more restricted when the Ca2+ concentration was increased. Hydrocarbons 74-85 carbonic anhydrase 2 Homo sapiens 178-181 3918999-4 1985 The activation of lecithin:cholesterol acyltransferase by apo-A-I and -A-IV differed, depending upon the nature of the hydrocarbon chains of the sn-L-alpha-phosphatidylcholine acyl donor. Hydrocarbons 119-130 lecithin-cholesterol acyltransferase Homo sapiens 18-54 3918999-4 1985 The activation of lecithin:cholesterol acyltransferase by apo-A-I and -A-IV differed, depending upon the nature of the hydrocarbon chains of the sn-L-alpha-phosphatidylcholine acyl donor. Hydrocarbons 119-130 apolipoprotein A1 Homo sapiens 58-75 3978755-4 1985 The characteristics of the reactions leading to the covalent binding of the N-methyl group of the azo derivative to microsomal protein and its metabolism to form the hydrocarbon, methane, possessed a number of similarities in the apparent kinetic parameters (Km and Vmax), induction, and inhibition patterns indicating a common pathway of metabolism to form a reactive intermediate and the involvement of cytochrome P-450. Hydrocarbons 166-177 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 405-421 6469956-0 1984 Competition between hydrocarbon and barbiturate for spectral binding to hepatic cytochrome P-450. Hydrocarbons 20-31 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 80-96 3979538-4 1985 It has been established that CCl4 extracts 36-89% of orthomenthane hydrocarbons exhibiting marked tropism to the fatty tissue from organ and tissue homogenates. Hydrocarbons 67-79 C-C motif chemokine ligand 4 Rattus norvegicus 29-33 6611202-2 1984 We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta. Hydrocarbons 62-73 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 153-169 6611202-2 1984 We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta. Hydrocarbons 62-73 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 186-214 6611202-2 1984 We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta. Hydrocarbons 62-73 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 216-219 6487589-3 1984 A symmetric and sharp wide-angle reflection at 4.11 A indicates that the hydrocarbon chains in hydrated C(18):C(10)PC bilayers are more tightly packed than in usual gel-state phosphatidylcholine bilayers and that there is no hydrocarbon chain tilt. Hydrocarbons 73-84 Bardet-Biedl syndrome 9 Homo sapiens 104-109 6487589-3 1984 A symmetric and sharp wide-angle reflection at 4.11 A indicates that the hydrocarbon chains in hydrated C(18):C(10)PC bilayers are more tightly packed than in usual gel-state phosphatidylcholine bilayers and that there is no hydrocarbon chain tilt. Hydrocarbons 225-236 Bardet-Biedl syndrome 9 Homo sapiens 104-109 6487589-6 1984 On the basis of these data, we propose a new lipid packing model for gel-state C(18):C(10)PC bilayers in which the long C(18) chain spans the entire width of the hydrocarbon region of the bilayer and the short C(10) chain aligns or abuts with the C(10) chain from the apposing molecule. Hydrocarbons 162-173 Bardet-Biedl syndrome 9 Homo sapiens 79-84 6487589-6 1984 On the basis of these data, we propose a new lipid packing model for gel-state C(18):C(10)PC bilayers in which the long C(18) chain spans the entire width of the hydrocarbon region of the bilayer and the short C(10) chain aligns or abuts with the C(10) chain from the apposing molecule. Hydrocarbons 162-173 Bardet-Biedl syndrome 9 Homo sapiens 120-125 6435901-2 1984 The major 3-methylcholanthrene (MC) inducible cytochrome P-450 (form c) exhibits the greatest activity toward both benzo[a]pyrene (BP) (58 min-1) and 7,12-dimethylbenz[a]anthracene (DMBA) (29 min-1) and forms substantially high spin, high affinity complexes (Kd = 10 nM) with both hydrocarbons. Hydrocarbons 281-293 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 46-62 6515735-0 1984 [Transketolase inhibitors based on disulfide derivatives of oxythiamine with branched hydrocarbon chains]. Hydrocarbons 86-97 transketolase Mus musculus 1-14 6611202-2 1984 We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta. Hydrocarbons 62-73 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 86-102 6487589-6 1984 On the basis of these data, we propose a new lipid packing model for gel-state C(18):C(10)PC bilayers in which the long C(18) chain spans the entire width of the hydrocarbon region of the bilayer and the short C(10) chain aligns or abuts with the C(10) chain from the apposing molecule. Hydrocarbons 162-173 homeobox C10 Homo sapiens 85-90 6812945-1 1982 Carcinogenic hydrocarbons benz[alpha] anthracene (BA), 7,12-dimethyl-BA (DMBA) and 3-methylcholanthrene (MC), bound non-covalently to bovine serum albumin (BSA), are photo-oxidized and become covalently bound to the protein as a result of irradiation at 365 nm. Hydrocarbons 13-25 albumin Homo sapiens 141-154 6690048-1 1984 In mice, there is a correlation between genetically regulated levels of inducible aryl hydrocarbon hydroxylase (AHH) activity and the risk of polycyclic hydrocarbon-induced leukemia or solid tumors. Hydrocarbons 87-98 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 112-115 6654528-2 1983 Ahb/Ahb and Ahb/Ahd mice have the high-affinity Ah receptor and therefore the polycyclic hydrocarbon induction of aryl hydrocarbon hydroxylase activity (cytochrome P1-450) proceeds with ease; Ahd/Ahd mice have the poor-affinity Ah receptor and this induction process proceeds more poorly, by a factor of at least 10-fold. Hydrocarbons 89-100 aryl-hydrocarbon receptor Mus musculus 228-239 6833234-6 1983 The other crystalline polymorph, designated beta 1, has a lamellar periodicity of 3.78 nm, which implies that in this form the hydrocarbon chains are tilted at approximately 40 degrees to the bilayer normal. Hydrocarbons 127-138 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 44-50 7126597-1 1982 Reversible inhibition of butyrylcholinesterase (acylcholine acylhydrolase, EC 3.1.1.8) with several aroma hydrocarbons was investigated and the results obtained were analyzed in terms of the hydrophobic interaction, making use of the solvent-water partition coefficients for the parameterization of the hydrophobic character of the ligand molecule. Hydrocarbons 106-118 butyrylcholinesterase Homo sapiens 25-46 6499814-1 1984 Halogenated hydrocarbons (CCl4, BrCCl3, 1,1-dichloroethylene, bromobenzene) cause a wide spectrum of dysfunction and injury in liver cells. Hydrocarbons 12-24 C-C motif chemokine ligand 4 Homo sapiens 26-30 6430894-4 1984 In the second approach, each hydrocarbon was incubated with a reconstituted system containing both cytochrome P-450c and epoxide hydrolase. Hydrocarbons 29-40 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 99-116 6209415-14 1984 Based on our data, a model for the interaction can be proposed: the first GM1 molecule is bound to the protein molecule through its head group and hydrocarbon chains, followed by the formation of a GM1/MBP complex with a concomitant conformational change of MBP as more GM1 is added. Hydrocarbons 147-158 myelin basic protein Homo sapiens 202-205 6310474-7 1983 It is suggested that the measurement of plasma ACE activity may be an adjunct in the assessment of the extent of lung injury in hydrocarbon aspiration in children. Hydrocarbons 128-139 angiotensin I converting enzyme Homo sapiens 47-50 6871211-1 1983 Using 13C cross-polarization NMR techniques, we have found that the effect of protein on the dynamics of the hydrocarbon interior of a series of biological membranes is to depress the intensity of motion on the nanosecond timescale (i.e., T1 becomes longer) and to enhance the intensity of motion on the timescale of tens of microseconds (i.e., T1p becomes shorter.) Hydrocarbons 109-120 CD5 molecule Homo sapiens 239-241 6871211-1 1983 Using 13C cross-polarization NMR techniques, we have found that the effect of protein on the dynamics of the hydrocarbon interior of a series of biological membranes is to depress the intensity of motion on the nanosecond timescale (i.e., T1 becomes longer) and to enhance the intensity of motion on the timescale of tens of microseconds (i.e., T1p becomes shorter.) Hydrocarbons 109-120 CD5 molecule Homo sapiens 345-348 6189709-3 1983 These polycyclic hydrocarbons increased severalfold the activity of the D-T diaphorase in intact and adrenalectomized animals. Hydrocarbons 17-29 NAD(P)H quinone dehydrogenase 1 Rattus norvegicus 72-86 6635254-0 1983 [Serum alanine aminotransferase, aspartate aminotransferase and beta-glucuronidase in petroleum refining workers exposed to hydrocarbons]. Hydrocarbons 124-136 glucuronidase beta Homo sapiens 64-82 7150417-4 1982 We have introduced it into the hydrocarbon layer of dimyristoylphosphatidylcholine vesicles in order to study their interaction with alpha-lactalbumin (alpha-LA) as a function of pH and temperature. Hydrocarbons 31-42 lactalbumin alpha Homo sapiens 133-150 7150417-4 1982 We have introduced it into the hydrocarbon layer of dimyristoylphosphatidylcholine vesicles in order to study their interaction with alpha-lactalbumin (alpha-LA) as a function of pH and temperature. Hydrocarbons 31-42 lactalbumin alpha Homo sapiens 152-160 7337851-0 1981 Use of reverse phase C-18 minicolumns for concentrating water-soluble hydrocarbons. Hydrocarbons 70-82 Bardet-Biedl syndrome 9 Homo sapiens 21-25 7118875-11 1982 Evidence was obtained that the hydrocarbons were bound at the substrate site in the heme-containing domain of the monooxygenase, P-448(1), and metabolized by the aid of NADPH-cytochrome P-450 reductase in the presence of NADPH and O2. Hydrocarbons 31-43 NADPH--cytochrome P450 reductase Oryctolagus cuniculus 169-201 7044012-2 1982 A series of pyrazoles containing an unsaturated hydrocarbon residue in the 4-position has been synthesized and tested for ability to inhibit the activity of the enzyme liver alcohol dehydrogenase. Hydrocarbons 48-59 aldo-keto reductase family 1 member A1 Homo sapiens 174-195 7089711-0 1982 [Abbreviated version of the National Contingency Plan for Combatting and Controlling Emissions of Hydrocarbons and Other Harmful Substances into the Sea]. Hydrocarbons 98-110 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 149-152 7194326-5 1981 Glass capillary gas-liquid chromatography revealed the following: a series of normal odd- and even-chain hydrocarbons (C16 to C32) for the steer and a complex pattern for the human samples; unsubstituted fatty acids in total lipids and various lipid classes ranging from C12 to C31 with n-even, n-odd, iso-even and iso-odd, and anteiso-odd chains for both samples; and fatty alcohols in total lipids and wax esters ranging from C18 to C31. Hydrocarbons 105-117 chemokine like factor Homo sapiens 126-129 6270682-11 1981 It is proposed that contact with the hydrocarbon core of membranes is established by C5b-7 through each of its subunits, by C5b-8 through C8, and by the MAC through C8 and, particularly, C9. Hydrocarbons 37-48 complement C5 Homo sapiens 85-88 6270682-11 1981 It is proposed that contact with the hydrocarbon core of membranes is established by C5b-7 through each of its subunits, by C5b-8 through C8, and by the MAC through C8 and, particularly, C9. Hydrocarbons 37-48 complement C5 Homo sapiens 124-127 6786734-2 1981 The major structural features are: (a) the adenine and polycyclic aromatic hydrocarbon residues lie nearly perpendicular to one another; (b) the conformation about the glycosidic bond is syn, rather than anti, and an internal hydrogen bond between the deoxyribose 5"-hydroxyl group and N(3) of the adenine residue is present; and (c) the more planar anthracene portion of the hydrocarbon is stacked between adenine residues of other molecules throughout the crystal. Hydrocarbons 75-86 synemin Homo sapiens 187-190 7263064-2 1981 RAG-1, a microorganism originally isolated for growth on hydrocarbon, adhered to epithelial cells when grown under conditions which promote its adherence to hexadecane; similarly, RAG-1 cells adhered poorly to epithelial cells when grown under conditions which cause the cells to possess low affinity towards hexadecane. Hydrocarbons 57-68 recombination activating 1 Homo sapiens 0-5 7263064-3 1981 A mutant derived from RAG-1, MR-481, deficient in its ability to adhere to hydrocarbon, was similarly unable to adhere to epithelial cells. Hydrocarbons 75-86 recombination activating 1 Homo sapiens 22-27 7016518-5 1981 In addition, a study on the influence of the chronic exposure to two polyhalogenated hydrocarbons, PCB and HCB, on several parameters of lymphocyte function in mice is presented. Hydrocarbons 85-97 pyruvate carboxylase Mus musculus 99-102 7016519-8 1981 Not only the dose but the route of administration and the tissue in which the malignancy or toxicity develops are therefore very important in the interpretation of data from tumorigenesis or toxicity experiments involving P1-450 inducers such as polycyclic hydrocarbons. Hydrocarbons 257-269 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 222-228 6783071-9 1981 A large change was observed in a protein vibrational band at 1340 cm-1 for pure vs. complexed apoA-I, indicating that protein hydrocarbon side chains are immobilized by lipid binding. Hydrocarbons 126-137 apolipoprotein A1 Homo sapiens 94-100 6452900-6 1981 The ability to reactivate ATPase activity was more dependent on the polar poly(oxyethylene) portion of nonionic detergents than on the hydrocarbon portion. Hydrocarbons 135-146 dynein axonemal heavy chain 8 Homo sapiens 26-32 7460072-9 1981 The 5--10-fold difference between cells from responsive and non-responsive mice in concentration of 3-MC needed to induce AHH maximally is taken to indicate that genes controlling aromatic hydrocarbon responsiveness in adult mouse livers in vivo also function in fetal mouse liver cells maintained in culture. Hydrocarbons 189-200 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 122-125 16345671-1 1980 Cultures of the marine pseudomonad UP-2 growing on n-tetracosane contained both free cells and cells bound to the solid hydrocarbon. Hydrocarbons 120-131 uroplakin 2 Homo sapiens 35-39 7333581-0 1981 Expression of aromatic polycyclic hydrocarbon-induced monooxygenase (aryl hydrocarbon hydroxylase) in man x mouse hybrids is associated with human chromosome 2. Hydrocarbons 34-45 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 69-97 7432538-1 1980 Genetic differences in the inducible arylhydrocarbon hydroxylase (EC 1.14.14.2) (AHH) system, which is involved in the multi-step metabolism of hydrocarbons, are known to exist in both humans and mice. Hydrocarbons 144-156 aryl hydrocarbon receptor repressor Homo sapiens 81-84 7426686-2 1980 Among the uncommon features of the observed processes were methyl acetate and C-2 and C-3 hydrocarbon expulsions and a few novel rearrangements. Hydrocarbons 90-101 complement C3 Homo sapiens 86-89 386760-1 1979 In a carcinogenesis bioassay of the brominated hydrocarbon 1,2-dibromoethane (also called ethylene dibromide or EDB), a gasoline and antiknock additive and soil and grain fumigant, oral administration by stomach tube caused cancers in rats and mice. Hydrocarbons 47-58 vesicle-associated membrane protein 8 Rattus norvegicus 112-115 464542-2 1979 The following working hypothesis is stated on the etiology of gynecologic tumors: "Environmental chemicals, such as cigarette smoke, polycyclic and polyhalogenated hydrocarbons, etc., induce special forms of cytochrome P-450 monooxygenase and related enzyme systems which can activate endogenous or prescribed estrogens and non-steroid antiestrogens to act as initiators and/or promoters of neoplasia in estrogen-dependent organs." Hydrocarbons 164-176 cytochrome P450 family 20 subfamily A member 1 Homo sapiens 208-238 7378385-4 1980 In both gel and liquid-crystal phases, the Raman line widths depend on the position of the CD2 group, being minimum at position 6 and increasing toward both ends of the hydrocarbon chain. Hydrocarbons 169-180 CD2 molecule Homo sapiens 91-94 427687-8 1979 Porphyria cutanea tarda, which is due to a deficiency of uroporphyrinogen decarboxylase, is manifested in association with alcohol abuse, estrogen therapy, exposure to chlorinated hydrocarbons or increased tissue iron stores, or a combination of these factors. Hydrocarbons 180-192 uroporphyrinogen decarboxylase Homo sapiens 57-87 456344-2 1979 The binding isotherms of bovine serum albumin with octylglucoside and decyl glucoside were determined at 7 degrees C and 25 degrees C at pH 7.4 and ionic strength 0.1 M. The average number of detergent molecules bound was found to increase with increasing hydrocarbon chain length. Hydrocarbons 256-267 albumin Homo sapiens 32-45 106274-9 1979 AR and MC are very good inducers of AHH activity in livers of mice classified as aromatic hydrocarbon responsive, but not in those classified as hydrocarbon nonresponsive. Hydrocarbons 90-101 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 36-39 423808-2 1979 The value of QO2 is higher on a mixture of n-alkanes (C12--C20) than on individual hydrocarbons whose availability is determined by the length of a hydrocarbon chain: C15 and C16-alkanes are oxidized best of all; C14, C13 and C12-alkanes are oxidized at a lower rate; and alkanes whose chain comprises less than ten carbon atoms are not oxidized at all. Hydrocarbons 83-95 placenta associated 8 Homo sapiens 167-170 423808-2 1979 The value of QO2 is higher on a mixture of n-alkanes (C12--C20) than on individual hydrocarbons whose availability is determined by the length of a hydrocarbon chain: C15 and C16-alkanes are oxidized best of all; C14, C13 and C12-alkanes are oxidized at a lower rate; and alkanes whose chain comprises less than ten carbon atoms are not oxidized at all. Hydrocarbons 83-94 placenta associated 8 Homo sapiens 167-170 517011-0 1979 Interaction of cytochrome P-450 with hydrocarbons. Hydrocarbons 37-49 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 15-31 517011-1 1979 Hydrocarbons of different structures interact with microsomal and solubilized cytochrome P-450 from liver of phenobarbital-pretreated rats forming a high spin enzyme-substrate type complex. Hydrocarbons 0-12 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 78-94 517011-2 1979 The affinity of cytochrome P-450 for hydrocarbons increases with increasing lipophilicity independently of the chemical structure. Hydrocarbons 37-49 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 16-32 517011-5 1979 Only one fraction of low spin form of solubilized cytochrome P-450 from rat liver interacts with hydrocarbons. Hydrocarbons 97-109 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 50-66 416909-1 1978 The C3H mouse liver h-protein is a cytoplasmic protein to which metabolites of carcinogenic polycyclic hydrocarbons bind covalently following i.p. Hydrocarbons 103-115 myosin binding protein H Mus musculus 20-29 890082-3 1977 However, the best substrates were pure linear hydrocarbons and particularly, n-C12, n-C13, and n-C14. Hydrocarbons 46-58 homeobox C13 Homo sapiens 86-89 26691-3 1978 The mobile phase used for chromatography on a reversed-phase column (C15 hydrocarbon permanently bonded to silica particles) is sufficiently acidic to induce fluorescence of furosemide. Hydrocarbons 73-84 placenta associated 8 Homo sapiens 69-72 407361-3 1977 (2) Increase of the length of hydrocarbon chain in homologues decreased Cth. Hydrocarbons 30-41 V-set and immunoglobulin domain containing 2 Homo sapiens 72-75 402584-0 1977 [The levels of chlorinated hydrocarbons in PCB in the bird population of West Germany]. Hydrocarbons 27-39 pyruvate carboxylase Homo sapiens 43-46 135754-6 1976 Cells grown on hexadecane and transferred to glucose metabolize intracellular hexadecane; after 1 day, activity of hexokinase, glucose-6-phosphate dehydrogenase, glucosephosphate isomerase, and succinate dehydrogenase could be detected and 22% of the intracellular hydrocarbon had been metabolized. Hydrocarbons 265-276 hexokinase 1 Homo sapiens 115-125 22175747-0 1976 Distribution of low-molecular-weight hydrocarbons in Southern Beaufort Sea. Hydrocarbons 37-49 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 71-74 807971-1 1975 The chlorinated hydrocarbons DDT and PCB"s (polychlorinated biphenyls), ubiquitous pollutants of the marine environment, have been observed to reduce the cell division rate of marine phytoplankton, thereby indirectly reducing the total photosynthetic carbon fixation in treated cultures. Hydrocarbons 16-28 pyruvate carboxylase Homo sapiens 37-40 134038-3 1976 The inhibitory effect of dipalmitoyllecithin on ATPase activity is probably related to the viscosity of the hydrocarbon region of the membrane which inhibits the conformational change leading to calcium translocation and the eventual cleavage of phosphoprotein. Hydrocarbons 108-119 dynein axonemal heavy chain 8 Homo sapiens 48-54 952908-8 1976 Human fibrinogen and bovin serum albumin were found to increase the I2890/I2850 dimyristoyl phosphatidylcholine Raman intensity ratio while decreasing the I2850/I2930 dimyristoyl phosphatidylcholine Raman intensity ratio indicating that the lipid underwent a conformational change and that the hydrocarbon chain environment was more polar in the presence of albumin or fibrinogen. Hydrocarbons 294-305 fibrinogen beta chain Homo sapiens 6-16 949475-6 1976 Bilayers prepared from extracted disk lipids had a microviscosity which was about one-fourth that of the intact disk membrane, demonstrating that rhodopsin hinders the mobility of the hydrocarbon chains of the disk phospholipids or egg phosphatidylcholine had identical microviscosities despite the much higher degree of unsaturation of the disk phospholipids. Hydrocarbons 184-195 rhodopsin Bos taurus 146-155 1229721-10 1975 With the start of lactation the concentration of chlorinated hydrocarbons especially of PCB"s are increased as could be shown with single samples. Hydrocarbons 61-73 pyruvate carboxylase Homo sapiens 88-91 820342-0 1976 Separate identities of ligandin and the h-protein, a major protein to which carcinogenic hydrocarbons are covalently bound. Hydrocarbons 89-101 myosin binding protein H Homo sapiens 40-49 984514-5 1976 Although statistically insufficient, these results confirm those of BRUCE, CULLEN and co workers, and thus demonstrate the immunodepressant properties of this saturated halogenated hydrocarbon. Hydrocarbons 181-192 baculoviral IAP repeat containing 6 Homo sapiens 68-73 240438-3 1975 From the evaluation of these constants as a function of alcohol concentration and hydrocarbon chain length, it is suggested that these alcohols interact specifically with lysozyme. Hydrocarbons 82-93 lysozyme Homo sapiens 171-179 167813-3 1975 The activation by apoA-I and apoC-I differed, depending upon the nature of the hydrocarbon chains of phosphatidylcholine acyl donor. Hydrocarbons 79-90 apolipoprotein A1 Homo sapiens 18-24 167012-4 1975 The ratio IE/IM is proportional to c/eta, where c is the microscopic concentration of the pyrene confined to the hydrocarbon region of the lipoprotein and eta is the microviscosity of that region. Hydrocarbons 113-124 endothelin receptor type A Homo sapiens 37-40 167813-3 1975 The activation by apoA-I and apoC-I differed, depending upon the nature of the hydrocarbon chains of phosphatidylcholine acyl donor. Hydrocarbons 79-90 apolipoprotein C1 Homo sapiens 29-35 4207380-0 1974 [Chlorinated hydrocarbons in the human fat]. Hydrocarbons 13-25 FAT atypical cadherin 1 Homo sapiens 39-42 168750-9 1975 The reconstituted enzyme system containing purified cytochrome P-450, purified NADPH-cytochrome P-450 reductase, and phosphatidylcholine retains the ability to catalyze the hydroxylation of drugs, fatty acids, hydrocarbons, and aniline in the presence of NADPH and molecular oxygen. Hydrocarbons 210-222 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 52-68 168750-9 1975 The reconstituted enzyme system containing purified cytochrome P-450, purified NADPH-cytochrome P-450 reductase, and phosphatidylcholine retains the ability to catalyze the hydroxylation of drugs, fatty acids, hydrocarbons, and aniline in the presence of NADPH and molecular oxygen. Hydrocarbons 210-222 cytochrome p450 oxidoreductase Rattus norvegicus 79-111 234834-4 1975 The observed correlation indicates determinants which are common to the elimination of antipyrine or phenylbutazone, and aryl hydrocarbon hydroxylase metabolism of hydrocarbons. Hydrocarbons 164-176 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 121-149 1116137-2 1975 Its properties are identical to the mouse skin h-protein, which may be primary arget of carcinogenic hydrocarbon metabolites during transformation to caner. Hydrocarbons 101-112 myosin binding protein H Mus musculus 47-56 5064941-0 1972 Polycyclic hydrocarbon-produced toxicity, transformation, and chromosomal aberrations as a function of aryl hydrocarbon hydroxylase activity in cell cultures. Hydrocarbons 11-22 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 103-131 9704074-5 1973 Polychlorinated biphenyls also were detected in trace amounts in the area of the chromatogram between the C(18) and the C(23) hydrocarbons. Hydrocarbons 126-138 nucleolin Homo sapiens 120-125 5084317-0 1972 Automatic gas chromatographic measurement of C 1 --C 5 hydrocarbons in air. Hydrocarbons 56-68 heterogeneous nuclear ribonucleoprotein C Homo sapiens 45-48 5084317-0 1972 Automatic gas chromatographic measurement of C 1 --C 5 hydrocarbons in air. Hydrocarbons 56-68 complement C5 Homo sapiens 51-54 4351804-1 1973 Immobilized insulin, prepared by coupling insulin directly to agarose or through hydrocarbon "connecting arms," was demonstrated to be capable of firmly binding intact adipocytes and their ghosts. Hydrocarbons 81-94 insulin Homo sapiens 12-19 4341702-3 1972 Rhodopsin appears to inhibit segmental motions of the hydrocarbon chains, an effect similar to that of cholesterol on phospholipid bilayers. Hydrocarbons 54-65 rhodopsin Homo sapiens 0-9 17774061-1 1967 Low-molecular-weight hydrocarbons in the C(l) to C(4) range have been detected and measured in sea water. Hydrocarbons 21-33 complement C4A (Rodgers blood group) Homo sapiens 49-53 5401121-0 1969 [Black Sea microorganisms growing on hydrocarbons]. Hydrocarbons 37-49 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 7-10 5762606-1 1969 As judged from the midpoints of the denaturation transition of 31 water-miscible alcohols, ureas, and amides, the effectiveness of these denaturing agents on sperm-whale myoglobin increases with increasing chain length and hydrocarbon content, as expected in view of the disorganization of the hydrophobic interior of this protein. Hydrocarbons 223-234 myoglobin Physeter catodon 170-179 33283479-0 2021 Structure-based Derivation and Optimization of YAP-like Coactivator-derived Peptides to Selectively Target TEAD Family Transcription Factors by Hydrocarbon Stapling and Cyclization. Hydrocarbons 144-155 Yes1 associated transcriptional regulator Homo sapiens 47-50 14813318-0 1950 [Does insulin increase the hydrocarbon requirement? Hydrocarbons 27-38 insulin Homo sapiens 6-13 33857583-8 2021 The present structure - activity analyses revealed that the dispersion force works not only on the halogens but also on the hydrocarbon groups, and that it is a major driving force of bifunctional ERalpha-agonist and ERbeta-antagonist activities. Hydrocarbons 124-135 estrogen receptor 1 Homo sapiens 197-204 33857583-8 2021 The present structure - activity analyses revealed that the dispersion force works not only on the halogens but also on the hydrocarbon groups, and that it is a major driving force of bifunctional ERalpha-agonist and ERbeta-antagonist activities. Hydrocarbons 124-135 estrogen receptor 1 Homo sapiens 217-223 6029668-0 1967 Toxicological studies with a hydrocarbon solvent, SBP 62/82. Hydrocarbons 29-40 selenium binding protein 1 Homo sapiens 50-53 14411132-0 1960 Influence of anions and cations with a long hydrocarbon chain on the thrombin-fibrinogen reaction. Hydrocarbons 44-55 coagulation factor II, thrombin Homo sapiens 69-77 33283479-2 2021 Here, we attempt to explore the systematic interaction profile between the 4 TEAD proteins and the peptides derived from the binding sites of 8 known YAP-like coactivators, in order to analyze the binding affinity and recognition specificity of these peptides towards the TEAD family, and to design hydrocarbon-stapled/cyclized peptides that can target the specific interaction profile for each coactivator. Hydrocarbons 299-310 Yes1 associated transcriptional regulator Homo sapiens 150-153 33756373-0 2021 Characteristics of hydrocarbons in hydrothermal products of the Clam hydrothermal field from the Okinawa trough. Hydrocarbons 19-31 CLAM Homo sapiens 64-68 33450065-2 2021 The extent of C18 hydrocarbon chain, conjugative rings and anion exchange site provided multiple retention mechanisms, including reversed phase liquid chromatography (RPLC), pi-pi interaction, hydrophilic interaction liquid chromatography (HILIC) and anion exchange chromatography (AEC). Hydrocarbons 18-29 Bardet-Biedl syndrome 9 Homo sapiens 14-17 33992999-1 2021 We conducted ex-situ catalytic fast co-pyrolysis (co-CFP) of corn stalk (CS) and high-density polyethylene (HDPE) over HZSM-5 catalyst to enhance the production of hydrocarbons. Hydrocarbons 164-176 citrate synthase Homo sapiens 73-75 33992999-3 2021 The synergisms between CS and HDPE were determined based on the difference between the experimental and theoretical CVOP and hydrocarbons content. Hydrocarbons 125-137 citrate synthase Homo sapiens 23-25 33756373-6 2021 Additionally, the present results suggest that the abiogenic contribution to source of hydrocarbons in hydrothermal products of the Clam hydrothermal field from the Okinawa Trough should not be ignored. Hydrocarbons 87-99 CLAM Homo sapiens 132-136 34043871-1 2021 In this work, the conventional reactions were used to functionalize the silica surface with amide and hydrocarbon chain groups affording two different mixed-mode stationary phases (Sil-amide-C11 and Sil-C12-amide). Hydrocarbons 102-113 STIL centriolar assembly protein Homo sapiens 181-184 33949858-10 2021 DTA and TGA profiles explain the relationship between hydrocarbon chain length, decomposition temperatures, and the energies required for decomposition. Hydrocarbons 54-65 T-box transcription factor 1 Homo sapiens 8-11 33848561-0 2021 Effect of Arsenic-containing Hydrocarbon on the Long-term Potentiation at Schaffer Collateral-CA1 Synapses from Infantile Male Rat. Hydrocarbons 29-40 carbonic anhydrase 1 Rattus norvegicus 94-97 33709793-3 2021 Cyclic voltammetry and ATR-SEIRAS results reveal that the FcC11SH modified substrate undergoes a reversible electron transfer and an associated re-orientation of both the ferrocene/ferrocenium headgroup and the hydrocarbon backbone. Hydrocarbons 211-222 ATR serine/threonine kinase Homo sapiens 23-26 33492353-0 2021 Relationship of Imported Fire Ant (Hymenoptera: Formicidae) Integument Coloration to Cuticular Hydrocarbon and Venom Alkaloid Profiles. Hydrocarbons 95-106 solute carrier family 25 member 6 Homo sapiens 30-33 33833468-3 2021 The column density of vinyl acetylene is (1.2+-0.2)x1013 cm-2, which makes it one of the most abundant closed-shell hydrocarbons detected in TMC-1. Hydrocarbons 116-128 transmembrane channel like 1 Homo sapiens 141-146 33662067-7 2021 Since isoprene is the most abundant hydrocarbon emitted into the atmosphere, and isoprene epoxydiols are the most important isoprene secondary organic aerosol precursors, our laboratory findings can aid in quantifying the direct radiative forcing of sulfates in the presence of organic compounds, thus more clearly resolving the impact of such aerosol particles on the Earth"s climate. Hydrocarbons 36-47 activation induced cytidine deaminase Homo sapiens 199-202 33782555-0 2021 Cryptic microbial hydrocarbon cycling. Hydrocarbons 18-29 cripto, FRL-1, cryptic family 1 Homo sapiens 0-7 33127147-1 2021 In the nocturnal boundary layer, nitrate radical (NO3) has an important contribution to atmospheric chemistry through oxidation of nitrogen oxides and hydrocarbons. Hydrocarbons 151-163 NBL1, DAN family BMP antagonist Homo sapiens 50-53 33848949-1 2021 The C1/C3 hydrocarbon gas separation characteristics of nanoporous carbon molecular sieves (CMS) are studied using DFT calculations and MD simulations. Hydrocarbons 10-21 heterogeneous nuclear ribonucleoprotein C Homo sapiens 4-9 33850332-8 2021 These results have been compared to state-of-the-art chemical models for TMC-1, indicating the important role of these hydrocarbons in its chemistry. Hydrocarbons 119-131 transmembrane channel like 1 Homo sapiens 73-78 33492922-0 2021 Efficacious CO2 Photoconversion to C2 and C3 Hydrocarbons on Upright SnS-SnS2 Heterojunction Nanosheet Frameworks. Hydrocarbons 45-57 sodium voltage-gated channel alpha subunit 11 Homo sapiens 73-77 33576222-1 2021 Atmospheric emissions from oil and gas production operations are composed of multiple hydrocarbons and can have large variations in composition. Hydrocarbons 86-98 gastrin Homo sapiens 35-38 33576222-3 2021 This work presents a database, constructed with empirical data and thermodynamic models, that can be queried to estimate hydrocarbon compositions from emission sources present at oil and gas production sites. Hydrocarbons 121-132 gastrin Homo sapiens 187-190 33645928-3 2021 This Minireivew presents a systematic discussion on the latest developments and separation mechanisms of metal-organic framework materials for C2 and C3 mixtures, discusses the problems faced by metal-organic framework materials in the study of light hydrocarbon adsorption and separation, and provides a reference for the design, preparation and process development of low-carbon hydrocarbon adsorption and separation materials in the future. Hydrocarbons 251-262 complement C2 Homo sapiens 143-152 33599525-2 2021 Mainly consisting of hydrocarbons, tars can, in principle, be measured using Fourier transform infrared (FT-IR) spectroscopy. Hydrocarbons 21-33 threonyl-tRNA synthetase 1 Homo sapiens 35-39 33213993-2 2021 Sewage sludge digestate is not only a good source of nutrients but is also rich in bacteria carrying alkB genes, which are involved in aliphatic hydrocarbons metabolism. Hydrocarbons 145-157 alkB homolog 1, histone H2A dioxygenase Homo sapiens 101-105 33557518-1 2021 We previously reported a family of hydrocarbon-stapled peptides designed to interact with the epidermal growth factor receptor (EGFR) juxtamembrane (JM) segment, blocking its ability to form a coiled coil dimer that is essential for receptor activation. Hydrocarbons 35-46 epidermal growth factor receptor Homo sapiens 94-126 33557518-1 2021 We previously reported a family of hydrocarbon-stapled peptides designed to interact with the epidermal growth factor receptor (EGFR) juxtamembrane (JM) segment, blocking its ability to form a coiled coil dimer that is essential for receptor activation. Hydrocarbons 35-46 epidermal growth factor receptor Homo sapiens 128-132 33492922-1 2021 In this work, SnS-SnS2 heterostructured upright nanosheet frameworks are constructed on FTO substrates, which demonstrate promising photocatalytic performances for the conversion of CO2 and water to C2 (acetaldehyde) and C3 (acetone) hydrocarbons without H2 formation. Hydrocarbons 234-246 sodium voltage-gated channel alpha subunit 11 Homo sapiens 18-22 33492922-5 2021 The Z-scheme SnS-SnS2 heterostructured nanosheet framework photocatalyst exhibits not only efficient charge separation but also highly catalytic active sites to boost the photocatalytic activity for CO2 conversion to C2 and C3 hydrocarbons. Hydrocarbons 227-239 sodium voltage-gated channel alpha subunit 11 Homo sapiens 17-21 33306399-1 2021 We report the synthesis and absolute configuration of monodeuterated cis-perhydroazulene (d1-1), which is a rare example of an isotopically chiral hydrocarbon whose synthesis and stereochemical analysis are known to be particularly difficult. Hydrocarbons 147-158 leiomodin 1 Homo sapiens 90-94 33521462-0 2021 Structural Evolution of Hydrocarbon-Rich Coal of the Late Carboniferous Taiyuan Formation in Dongpu Sag. Hydrocarbons 24-35 S-antigen visual arrestin Homo sapiens 100-103 33376864-0 2020 Hydrocarbon Generation Potential and Depositional Setting of Eocene Oil-Prone Coaly Source Rocks in the Xihu Sag, East China Sea Shelf Basin. Hydrocarbons 0-11 S-antigen visual arrestin Homo sapiens 109-112 33381489-4 2020 NSF is composed mainly of C12-C22 hydrocarbons, and is characterized by low impurity content, small specific gravity, and easy degradation. Hydrocarbons 34-46 N-ethylmaleimide sensitive factor, vesicle fusing ATPase Homo sapiens 0-3 33374799-6 2020 Aldehydes and hydrocarbons reached their peaks at S16, acids and ketones remained constant from R6 to S16, whereas esters started decreasing after 12 months of seasoning. Hydrocarbons 14-26 ribosomal protein S16 Homo sapiens 50-53 33376864-1 2020 The Xihu Sag in the East China Sea Shelf Basin is a focus for hydrocarbon exploration and development. Hydrocarbons 62-73 S-antigen visual arrestin Homo sapiens 9-12 33376864-2 2020 Hydrocarbons in the Xihu Sag are believed to have mainly originated from coals in the Paleogene Pinghu Formation (shortened as Pinghu coal). Hydrocarbons 0-12 S-antigen visual arrestin Homo sapiens 25-28 33376864-9 2020 Areas in the Xihu sag with considerable thicknesses of coal should be paid particular attention for future hydrocarbon exploration. Hydrocarbons 107-118 S-antigen visual arrestin Homo sapiens 18-21 33112316-7 2020 Accordingly, we provide perspectives on current challenges and future emphases in designing MOF materials for hydrocarbon separation. Hydrocarbons 110-121 lysine acetyltransferase 8 Homo sapiens 92-95 33174715-9 2020 The comparison of the results obtained by TLSE-ATR-FTIR to the results of conventional analyses carried out by accredited laboratories confirms that the use of the proposed method can become an effective alternative to the current methods for the determination of the total hydrocarbons in soils. Hydrocarbons 274-286 ATR serine/threonine kinase Homo sapiens 47-50 32472581-1 2020 An unprecedented direct atom-economic chemo- and regioselective hydroalkylation of chloroalkynes and an sp3-C,H alkynylation of bromoalkynes was achieved, reaction partners are unfunctionalized ethers, alcohols, amides, and even non-activated hydrocarbons. Hydrocarbons 243-255 Sp3 transcription factor Homo sapiens 104-107 32905848-2 2020 The Deepwater Horizon oil rig explosion created the largest environmental disaster in U.S. history, and the second largest oil spill in human history with over 800 million liters of hydrocarbons released into the Gulf of Mexico over a period of 3 months. Hydrocarbons 182-194 dickkopf WNT signaling pathway inhibitor 3 Homo sapiens 26-29 33112316-8 2020 With our continued efforts in this area, we expect that integrating supramolecular interactions in a single MOF system is a viable approach to achieve a balance between adsorption capacity and selectivity for different hydrocarbon separation scenarios. Hydrocarbons 219-230 lysine acetyltransferase 8 Homo sapiens 108-111 33214800-5 2020 After analyzing the pyrolysis product-semicoke (SC) and SO-with ATR-FTIR and GC-MS methods, CumNin/SA promotes the secondary cracking and aromatization of OS pyrolysis, increasing the content of the compound of olefins and aromatics in SO, and hastening the decomposition of long-chain aliphatic hydrocarbons to short-chain aliphatic hydrocarbons. Hydrocarbons 296-308 acyl-CoA synthetase medium chain family member 3 Homo sapiens 92-101 33214800-5 2020 After analyzing the pyrolysis product-semicoke (SC) and SO-with ATR-FTIR and GC-MS methods, CumNin/SA promotes the secondary cracking and aromatization of OS pyrolysis, increasing the content of the compound of olefins and aromatics in SO, and hastening the decomposition of long-chain aliphatic hydrocarbons to short-chain aliphatic hydrocarbons. Hydrocarbons 334-346 acyl-CoA synthetase medium chain family member 3 Homo sapiens 92-101 32906885-5 2020 It can achieve noise equivalent detection limits in the order of 100 ppbv Hz-1/2 for various hydrocarbons, alcohols, and aldehydes. Hydrocarbons 93-105 hz-1/2 None 74-80 33072605-9 2020 Gene-environment interaction analysis showed that NAT2 rs1799929 TT genotype confers high risk to ALL under exposure to fertilizers, insecticides, hydrocarbon derivatives, and parental tobacco smoking. Hydrocarbons 147-158 N-acetyltransferase 2 Homo sapiens 50-54 32882139-1 2020 To help address efficient separation of C2Hn light hydrocarbons and C2H2/CO2 in the chemical industry, the self-assembly via an azolate-carboxylate ligand and Co(II) ion gave rise to a new porous MOF material, [Co(btzip)(H2btzip)] 2DMF 2H2O (1) (H2btzip = 4,6-bis(triazol-1-yl)isophthalic acid). Hydrocarbons 51-63 mitochondrially encoded cytochrome c oxidase II Homo sapiens 159-165 32790354-4 2020 The aryl hydrocarbon (AhR) and pregnane X (PXR) transcription factors showed the greatest upregulation; with HLB exceeding DCM-total, and no upregulation in the hydrocarbon fraction (DCM-SGC). Hydrocarbons 9-20 aryl hydrocarbon receptor Homo sapiens 22-25 32813523-3 2020 From an energetic perspective, perfluorinated hydrocarbons with sp, sp2, or sp3 C-hybridization are unable to form a XB with a N-base but a very weak bond can be formed if electron-withdrawing C N substituents are added to the acid. Hydrocarbons 46-58 Sp2 transcription factor Homo sapiens 68-71 32813523-3 2020 From an energetic perspective, perfluorinated hydrocarbons with sp, sp2, or sp3 C-hybridization are unable to form a XB with a N-base but a very weak bond can be formed if electron-withdrawing C N substituents are added to the acid. Hydrocarbons 46-58 Sp3 transcription factor Homo sapiens 76-79 32701273-7 2020 We validate the accuracies of f-ACKS2 and scf-ACKS2 by comparing polarization energies and induced dipole moments for a number of charged hydrocarbon dimers against DFT reference calculations. Hydrocarbons 138-149 KIT ligand Homo sapiens 42-45 32789711-0 2020 Dominance Hierarchy, Ovarian Activity and Cuticular Hydrocarbons in the Primitively Eusocial Wasp Mischocyttarus cerberus (Vespidae, Polistinae, Mischocyttarini). Hydrocarbons 52-64 WASP actin nucleation promoting factor Homo sapiens 93-97 32789711-0 2020 Dominance Hierarchy, Ovarian Activity and Cuticular Hydrocarbons in the Primitively Eusocial Wasp Mischocyttarus cerberus (Vespidae, Polistinae, Mischocyttarini). Hydrocarbons 52-64 cerberus 1, DAN family BMP antagonist Homo sapiens 113-121 32789711-6 2020 In this study, we investigated the connection between cuticular hydrocarbons in females expressed in different social contexts in the primitively eusocial wasp Mischocyttarus cerberus. Hydrocarbons 64-76 WASP actin nucleation promoting factor Homo sapiens 155-159 32789711-6 2020 In this study, we investigated the connection between cuticular hydrocarbons in females expressed in different social contexts in the primitively eusocial wasp Mischocyttarus cerberus. Hydrocarbons 64-76 cerberus 1, DAN family BMP antagonist Homo sapiens 175-183 32907722-5 2020 Bioavailability of hydrocarbons was evident particularly for high molecular weight PAHs, which also caused significant variations of cellular biomarkers, such as cytochrome P450 metabolization in fish, lysosomal membrane destabilization in mussels, genotoxic effects both in fish and molluscs. Hydrocarbons 19-31 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 162-177 31701390-3 2020 Due to the long-term hydrocarbon contamination and exposure to aerobic and anaerobic biodegradation mechanisms, the lowest concentrations of O2, NO3-, and SO42- (electron acceptors) and the highest concentrations of Mn and Fe (products of microbial metabolic activity) overlap. Hydrocarbons 21-32 NBL1, DAN family BMP antagonist Homo sapiens 145-148 32600036-4 2020 XDS located protein-density near the phospholipid headgroup and in the hydrocarbon core, presumed to be SP-B and SP-C, respectively. Hydrocarbons 71-82 surfactant protein B Bos taurus 104-108 32600036-4 2020 XDS located protein-density near the phospholipid headgroup and in the hydrocarbon core, presumed to be SP-B and SP-C, respectively. Hydrocarbons 71-82 surfactant protein C Bos taurus 113-117 32279449-4 2020 We used Aminohexanoic acid (Ahx) as a hydrocarbon linker to generate 99m Tc-(tricine/EDDA)-HYNIC-Ahx-[D-Lys6 ]GnRH. Hydrocarbons 38-49 gonadotropin releasing hormone 1 Homo sapiens 110-114 32339835-9 2020 For C10 to C12 linear isomers, the degradation rate increased together with the length of the hydrocarbon chain. Hydrocarbons 94-105 chromosome 12 open reading frame 57 Homo sapiens 4-7 32803027-2 2020 One of the major concerns especially in waters like the South China Sea is the deposition of wax on the walls of the pipeline or wellbore, constricting and hindering the hydrocarbon flow. Hydrocarbons 170-181 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 68-71 32348108-0 2020 Hydrocarbon-stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor. Hydrocarbons 0-11 glucagon like peptide 1 receptor Homo sapiens 41-73 32580524-5 2020 Operando FT-IR-GC studies confirmed a higher fraction of short-chain hydrocarbons (C3-C5) in the product distribution of hierarchical catalysts resulting from the effective polymer cracking in easily accessible pores. Hydrocarbons 69-81 ADAM metallopeptidase with thrombospondin type 1 motif 1 Homo sapiens 83-88 32348108-5 2020 Whereas mutagenesis and lipidation strategies have yielded clinical agents, we developed an alternative approach to preserving the structure and function of GLP-1 by all-hydrocarbon i, i+7 stitching. Hydrocarbons 170-181 glucagon Homo sapiens 157-162 32182919-0 2020 Geochemical and Geophysical Monitoring of Hydrocarbon Seepage in the Adriatic Sea. Hydrocarbons 42-53 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 78-81 32291897-4 2020 Since this reaction is barrierless, exoergic, and all transition states are located below the energy of the separated reactants, these cyclic C 5 H 6 products are predicted to be accessed even in low-temperature environments, such as in hydrocarbon-rich atmospheres of planets and cold molecular clouds such as TMC-1. Hydrocarbons 237-248 transmembrane channel like 1 Homo sapiens 311-316 32149448-1 2020 Linearly fused hydrocarbon nanobelts are a unique type of double-stranded macrocycles that would serve as not only the powerful hosts in supramolecular science but also the templates to grow zig-zag carbon nanotubes with defined diameters. Hydrocarbons 15-26 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 195-198 31773793-9 2020 The combination of ESI/APPI favors hydrocarbons and oxygen containing species. Hydrocarbons 35-47 amyloid beta precursor protein Homo sapiens 23-27 32462154-1 2020 The stepwise solvation of various cationic coronene oligomers by para-hydrogen (p-H2) molecules was computationally investigated using a united-atom model for the p-H2 molecules and the Silvera-Goldman potential, together with a polarizable description for the interaction with the hydrocarbon molecules. Hydrocarbons 282-293 polyhomeotic homolog 2 Homo sapiens 80-84 32123339-4 2020 Here we combined NMR and computational analysis to show that all-syn contiguously methyl-substituted hydrocarbons, with chain lengths from C6 to C11, exhibit a dramatic odd-even effect in helical propensity. Hydrocarbons 101-113 RNA polymerase III subunit K Homo sapiens 145-148 32353067-6 2020 We find that not only the epitope residues (F19, W23 and L26), but also the hydrocarbon linker of the stapled p53 impart significant contributions. Hydrocarbons 76-87 tumor protein p53 Homo sapiens 110-113 31965671-2 2020 This is the first synthesis of a rearranged spongian diterpenoid in which the bulky hydrocarbon fragment is joined via a quaternary carbon to the highly hindered concave face of the cis-2,8-dioxabicyclo[3.3.0]octan-3-one moiety. Hydrocarbons 84-95 suppressor of cytokine signaling 2 Homo sapiens 182-187 31964625-2 2020 Here, we identified the polarizing conditions to induce an IL22 producing CD8+ Tc22 subset, which is dependent on IL6 and the aryl hydrocarbon receptor transcription factor. Hydrocarbons 126-142 interleukin 22 Homo sapiens 59-63 31964625-2 2020 Here, we identified the polarizing conditions to induce an IL22 producing CD8+ Tc22 subset, which is dependent on IL6 and the aryl hydrocarbon receptor transcription factor. Hydrocarbons 126-142 CD8a molecule Homo sapiens 74-77 31647966-3 2020 METHODS: The relationship between PM2.5 exposure and asthma severity was investigated in an asthma model with CD4+ T cell-specific aryl hydrocarbon receptor (AhR) null mice. Hydrocarbons 131-147 aryl-hydrocarbon receptor Mus musculus 158-161 31902468-7 2020 In this review, we present important, recent developments in the computational prediction of the inhibition of four clinically crucial CYP isoforms (CYP1A2, 2C9, 2D6, and 3A4) and three nuclear receptors (aryl hydrocarbon receptor, constitutive androstane receptor, and pregnane X receptor) involved in the induction of CYP1A2, 2B6, and 3A4, respectively. Hydrocarbons 205-221 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 135-138 31759816-0 2020 Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene. Hydrocarbons 99-115 aryl hydrocarbon receptor nuclear translocator Homo sapiens 130-134 31715395-1 2020 To efficiently and selectively produce liquid hydrocarbon fuels, e.g., methanol, by CO2 photoelectrochemical reduction, CdS nanoparticles (NPs) anchored on the nitrogen-doped carbon particles (NCP) with core-shell dodecahedral porous structure were used as cathode catalysts. Hydrocarbons 46-57 CDP-diacylglycerol synthase 1 Homo sapiens 120-123 31678681-0 2020 TCDD-mediated suppression of naive human B cell IgM secretion involves aryl hydrocarbon receptor-mediated reduction in STAT3 serine 727 phosphorylation and is restored by Interferon-gamma. Hydrocarbons 71-87 signal transducer and activator of transcription 3 Homo sapiens 119-124 31706640-0 2020 Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASG12C. Hydrocarbons 51-62 SOS Ras/Rac guanine nucleotide exchange factor 1 Homo sapiens 71-75 31706640-5 2020 Here, we report the design and development of a series of hydrocarbon-stapled peptides containing d-amino acids to mimic the alpha helix of SOS1. Hydrocarbons 58-69 SOS Ras/Rac guanine nucleotide exchange factor 1 Homo sapiens 140-144 31900379-0 2020 Withdrawal: HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. Hydrocarbons 81-97 histone deacetylase 6 Homo sapiens 12-17 31125161-9 2019 These data support an important role for FASN3 in the biosynthesis of the precursors to hydrocarbons that waterproof the insect cuticle. Hydrocarbons 88-100 Fatty acid synthase 3 Drosophila melanogaster 41-46 31586754-0 2020 Molecular modeling and rational design of hydrocarbon-stapled/halogenated helical peptides targeting CETP self-binding site: Therapeutic implication for atherosclerosis. Hydrocarbons 42-53 cholesteryl ester transfer protein Homo sapiens 101-105 31893230-1 2019 Oxide-derived copper catalysts have been shown to enhance CO2 reduction reaction (CO2RR) activity with high selectivity toward hydrocarbon products. Hydrocarbons 127-138 complement C2 Homo sapiens 58-61 31609611-2 2019 Abstract DFT calculations (B3LYP/6-311+G(d,p) )have been employed to reexamine the mechanism of the oxidation of saturated hydrocarbons and the epoxidation of alkenes with a series of hydroperoxides, alpha-hydroxy perhydrates and peroxyacids. Hydrocarbons 123-135 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 29-32 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 AKT serine/threonine kinase 1 Homo sapiens 449-452 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 catenin beta 1 Homo sapiens 480-492 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 high mobility group box 1 Homo sapiens 511-537 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 high mobility group box 1 Homo sapiens 539-544 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 advanced glycosylation end-product specific receptor Homo sapiens 592-596 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 aryl hydrocarbon receptor Homo sapiens 603-628 31849690-4 2019 In this pathological process, PM2.5 particles, excessive reactive oxygen species (ROS) derived from PM2.5, and certain components in PM2.5, such as ions and polyaromatic hydrocarbons (PAHs), have been implicated as potential EMT mediators that are linked to the activation of transforming growth factor beta (TGF-beta)/SMADs, NF-kappaB, growth factor (GF)/extracellular signal-regulated protein kinase (ERK), GF/phosphatidylinositol 3-kinase (PI3K)/Akt, wingless/integrated (Wnt)/beta-catenin, Notch, Hedgehog, high mobility group box B1 (HMGB1)-receptor for advanced glycation end-products (RAGE), and aryl hydrocarbon receptor (AHR) signaling cascades and to cytoskeleton rearrangement. Hydrocarbons 184-188 aryl hydrocarbon receptor Homo sapiens 630-633 31601100-1 2019 Nanothreads are one-dimensional sp3 hydrocarbons that pack within pseudohexagonal crystalline lattices. Hydrocarbons 36-48 Sp3 transcription factor Homo sapiens 32-35 31692812-0 2019 Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide. Hydrocarbons 37-48 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 26-31 31343760-15 2019 Three fast steps are necessary for the application to any aliphatic hydrocarbon or alcohol: (1) An SCF calculation at the selected molecular geometry; it can be fast since a medium size basis set is generally sufficient. Hydrocarbons 68-79 KIT ligand Homo sapiens 99-102 31692812-4 2019 To address this we tested the potency of a hydrocarbon stapled BIM BH3 peptide (BIM SAHB A ) to overcome both BCL-2 and MCL-1 apoptotic resistance given BIM"s naturally wide ranging affinity for all BCL-2 family multidomain members. Hydrocarbons 43-54 BCL2 apoptosis regulator Homo sapiens 110-115 31692812-4 2019 To address this we tested the potency of a hydrocarbon stapled BIM BH3 peptide (BIM SAHB A ) to overcome both BCL-2 and MCL-1 apoptotic resistance given BIM"s naturally wide ranging affinity for all BCL-2 family multidomain members. Hydrocarbons 43-54 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 120-125 31695491-1 2019 Background: TIPARP (TCDD-inducible poly-ADP-ribose polymerase), a mono-ADP-ribosyltransferase and a transcriptional repressor of aryl hydrocarbon receptor (AHR), was one of the potential therapeutic targets for human cancers identified by CRISPR-Cas9 screens recently. Hydrocarbons 129-145 TCDD inducible poly(ADP-ribose) polymerase Homo sapiens 12-18 31695491-1 2019 Background: TIPARP (TCDD-inducible poly-ADP-ribose polymerase), a mono-ADP-ribosyltransferase and a transcriptional repressor of aryl hydrocarbon receptor (AHR), was one of the potential therapeutic targets for human cancers identified by CRISPR-Cas9 screens recently. Hydrocarbons 129-145 TCDD inducible poly(ADP-ribose) polymerase Homo sapiens 20-61 31695491-1 2019 Background: TIPARP (TCDD-inducible poly-ADP-ribose polymerase), a mono-ADP-ribosyltransferase and a transcriptional repressor of aryl hydrocarbon receptor (AHR), was one of the potential therapeutic targets for human cancers identified by CRISPR-Cas9 screens recently. Hydrocarbons 129-145 aryl hydrocarbon receptor Homo sapiens 156-159 31488357-3 2019 Herein, we report the effect of replacing the adamantane group by alternative polycyclic hydrocarbons on sEH inhibition, solubility, permeability and metabolic stability. Hydrocarbons 89-101 epoxide hydrolase 2 Homo sapiens 105-108 31614583-4 2019 The hydrocarbon degradation activity, measured as the number of culturable hydrocarbonoclastic bacteria (CHB) and by the copy number of the alkB gene, was relatively low at the beginning of the experiment. Hydrocarbons 4-15 alkB homolog 1, histone H2A dioxygenase Homo sapiens 140-144 31832575-4 2019 The expression of miR-10a was rhythmic and down-regulated the expression of the circadian rhythm gene brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (Bmal1) by directly suppressing the expression of RA receptor-related orphan receptor alpha (RORA). Hydrocarbons 119-135 microRNA 10a Homo sapiens 18-25 31220339-3 2019 We proposed that a hydrocarbon-stapled mimetic of relaxin-3, when administered intranasally, might be uniquely applicable to the treatment of these disorders. Hydrocarbons 19-30 relaxin 3 Rattus norvegicus 50-59 31220339-4 2019 EXPERIMENTAL APPROACH: We designed a series of hydrocarbon-stapled relaxin-3 mimetics and identified the most potent compound using in vitro receptor binding and activation assays. Hydrocarbons 47-58 relaxin 3 Rattus norvegicus 67-76 31195271-9 2019 Moreover, hydrocarbon degradation rates were slightly higher when using F-PS than S-PS due to a lower surfactant content in the targeted zone. Hydrocarbons 10-21 farnesyl diphosphate synthase Homo sapiens 72-76 31575165-5 2019 The multiple band systems are attributed to spin-orbit splitting and vibronic transitions involving metal-hydrocarbon and hydrocarbon-based vibrations. Hydrocarbons 106-117 spindlin 1 Homo sapiens 44-48 31575165-5 2019 The multiple band systems are attributed to spin-orbit splitting and vibronic transitions involving metal-hydrocarbon and hydrocarbon-based vibrations. Hydrocarbons 122-133 spindlin 1 Homo sapiens 44-48 31575165-8 2019 The remaining Ce 5d electrons in the isolated atom are spin paired in molecular orbitals that are a bonding combination between Ce 5dpi and hydrocarbon pi* orbitals. Hydrocarbons 140-151 spindlin 1 Homo sapiens 55-59 31832575-4 2019 The expression of miR-10a was rhythmic and down-regulated the expression of the circadian rhythm gene brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (Bmal1) by directly suppressing the expression of RA receptor-related orphan receptor alpha (RORA). Hydrocarbons 119-135 aryl hydrocarbon receptor nuclear translocator like Homo sapiens 174-179 31832575-4 2019 The expression of miR-10a was rhythmic and down-regulated the expression of the circadian rhythm gene brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (Bmal1) by directly suppressing the expression of RA receptor-related orphan receptor alpha (RORA). Hydrocarbons 119-135 RAR related orphan receptor A Homo sapiens 266-270 31943992-3 2019 The [TCM]- anion shows the largest chemical shift deviations, but the [NTf2 ]- anion has the highest hydrocarbon solubility due to steric effects. Hydrocarbons 101-112 nuclear transport factor 2 Homo sapiens 71-75 31464059-0 2019 Catalytic One-Pot Conversion of Renewable Platform Chemicals to Hydrocarbon and Ether Biofuels via Tandem Hf(OTf)4 + Pd/C Catalysis. Hydrocarbons 64-75 POU class 5 homeobox 1 Homo sapiens 109-114 31403074-12 2019 Additionally, iso-MOF-4 also possesses efficient separation of C3H8/CH4 and C2H6/CH4, indicating its promising potential in storage/separation of light hydrocarbons in industry. Hydrocarbons 152-164 lysine acetyltransferase 8 Homo sapiens 18-21 30776182-7 2019 First, the four non-interfacial residues of HRc peptide are artificially substituted with new amino acid combinations of high helical propensity and, second, the helical conformation of wild-type and mutant HRc peptides is stabilized by adding an all-hydrocarbon bridge across two spatially vicinal, non-interfacial residues 503 (i) and 507 (i + 4). Hydrocarbons 251-262 histidine rich calcium binding protein Homo sapiens 44-47 30776182-7 2019 First, the four non-interfacial residues of HRc peptide are artificially substituted with new amino acid combinations of high helical propensity and, second, the helical conformation of wild-type and mutant HRc peptides is stabilized by adding an all-hydrocarbon bridge across two spatially vicinal, non-interfacial residues 503 (i) and 507 (i + 4). Hydrocarbons 251-262 histidine rich calcium binding protein Homo sapiens 207-210 31403074-0 2019 Fine-Tuning the Pore Environment of the Microporous Cu-MOF for High Propylene Storage and Efficient Separation of Light Hydrocarbons. Hydrocarbons 120-132 lysine acetyltransferase 8 Homo sapiens 55-58 31087744-1 2019 Diamondoids, sp3 -hybridized nanometer-sized diamond-like hydrocarbons (nanodiamonds), difunctionalized with hydroxy and primary phosphine oxide groups, enable the assembly of the first sp3 -C-based chemical sensors by vapor deposition. Hydrocarbons 58-70 Sp3 transcription factor Homo sapiens 13-16 31087744-1 2019 Diamondoids, sp3 -hybridized nanometer-sized diamond-like hydrocarbons (nanodiamonds), difunctionalized with hydroxy and primary phosphine oxide groups, enable the assembly of the first sp3 -C-based chemical sensors by vapor deposition. Hydrocarbons 58-70 Sp3 transcription factor Homo sapiens 186-189 31226791-14 2019 Overall, macrocyclization by hydrocarbon stapling appears to overcome the destabilization of alpha-helicity by helix breaking residues and, in the specific case of d-Trp7-modification, a highly potent ATSP-7041 analog (Mdm2 Kd = 30 nM; cellular EC50 = 600 nM) was identified. Hydrocarbons 29-40 transient receptor potential cation channel subfamily C member 7 Homo sapiens 166-170 31055798-9 2019 Xenograft tumor samples analyzed by chromatin immunoprecipitation confirmed that HIF1alpha-aryl hydrocarbon nuclear translocator and GILZ bind to the TSC22D3 (GILZ) and FVII gene loci, respectively, thereby potentially modulating chromatin function to augment FVII transcription. Hydrocarbons 96-107 hypoxia inducible factor 1 subunit alpha Homo sapiens 81-90 31055798-9 2019 Xenograft tumor samples analyzed by chromatin immunoprecipitation confirmed that HIF1alpha-aryl hydrocarbon nuclear translocator and GILZ bind to the TSC22D3 (GILZ) and FVII gene loci, respectively, thereby potentially modulating chromatin function to augment FVII transcription. Hydrocarbons 96-107 TSC22 domain family member 3 Homo sapiens 150-157 31055798-9 2019 Xenograft tumor samples analyzed by chromatin immunoprecipitation confirmed that HIF1alpha-aryl hydrocarbon nuclear translocator and GILZ bind to the TSC22D3 (GILZ) and FVII gene loci, respectively, thereby potentially modulating chromatin function to augment FVII transcription. Hydrocarbons 96-107 TSC22 domain family member 3 Homo sapiens 159-163 31226791-14 2019 Overall, macrocyclization by hydrocarbon stapling appears to overcome the destabilization of alpha-helicity by helix breaking residues and, in the specific case of d-Trp7-modification, a highly potent ATSP-7041 analog (Mdm2 Kd = 30 nM; cellular EC50 = 600 nM) was identified. Hydrocarbons 29-40 MDM2 proto-oncogene Homo sapiens 219-223 30702183-1 2019 Sediment from a log pond located in south Finland contained 15 000 to 50 000 mg/kg dry weight of C10 -C40 hydrocarbons. Hydrocarbons 106-118 homeobox C10 Homo sapiens 97-100 30851618-0 2019 Molecular evolution of the plant ECERIFERUM1 and ECERIFERUM3 genes involved in aliphatic hydrocarbon production. Hydrocarbons 89-100 Fatty acid hydroxylase superfamily Arabidopsis thaliana 33-44 30851618-3 2019 CER1 enzymes can be used to produce alternative and sustainable hydrocarbons in eukaryotic systems. Hydrocarbons 64-76 Fatty acid hydroxylase superfamily Arabidopsis thaliana 0-4 30731167-4 2019 Here, we attempt to explore the systematic interaction profile between the five DAX1/SHP LXXLL motifs and all the 48 hNR AF-2 domains found in the human genome, to analyze the binding affinity and specificity of these motifs towards the complete domain array, and to design LXXLL-based, hydrocarbon-stapled peptides that can target the specific interaction profile for each motif. Hydrocarbons 287-298 nuclear receptor subfamily 0 group B member 1 Homo sapiens 80-84 31316744-1 2019 All-hydrocarbon, i, i+7 stapled peptide inhibitors of the p53-Mdm2 interaction have emerged as promising new leads for cancer therapy. Hydrocarbons 4-15 tumor protein p53 Homo sapiens 58-61 31316744-1 2019 All-hydrocarbon, i, i+7 stapled peptide inhibitors of the p53-Mdm2 interaction have emerged as promising new leads for cancer therapy. Hydrocarbons 4-15 MDM2 proto-oncogene Homo sapiens 62-66 31143165-1 2019 The Caspian Sea, which is the largest landlocked body of water on the planet, receives substantial annual hydrocarbon input from anthropogenic sources (e.g., industry, agriculture, oil exploration, and extraction) and natural sources (e.g., mud volcanoes and oil seeps). Hydrocarbons 106-117 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 12-15 31086813-2 2019 Using hydrocarbon-stapled peptide technologies, we aim to develop potent, selective inhibitors targeting this pathway by disrupting the interaction of beta-cat with its coactivators B-cell lymphoma 9 (BCL9) and B-cell lymphoma 9-like (B9L). Hydrocarbons 6-17 BCL9 transcription coactivator Homo sapiens 182-199 31086813-2 2019 Using hydrocarbon-stapled peptide technologies, we aim to develop potent, selective inhibitors targeting this pathway by disrupting the interaction of beta-cat with its coactivators B-cell lymphoma 9 (BCL9) and B-cell lymphoma 9-like (B9L). Hydrocarbons 6-17 BCL9 transcription coactivator Homo sapiens 211-228 30702183-1 2019 Sediment from a log pond located in south Finland contained 15 000 to 50 000 mg/kg dry weight of C10 -C40 hydrocarbons. Hydrocarbons 106-118 CCR4-NOT transcription complex subunit 11 Homo sapiens 102-105 30504015-8 2019 The C3-C5 RONO2 were mainly produced from the photochemical oxidation of their parent hydrocarbons (i.e., C3-C5 alkanes), whilst C1-C2 RONO2 compounds have additional sources. Hydrocarbons 86-98 ADAM metallopeptidase with thrombospondin type 1 motif 1 Homo sapiens 4-9 31118901-0 2019 Pleiotropic Effects of ebony and tan on Pigmentation and Cuticular Hydrocarbon Composition in Drosophila melanogaster. Hydrocarbons 67-78 ebony Drosophila melanogaster 23-28 31118901-3 2019 Here, we present evidence that two pigmentation genes, ebony and tan, which encode enzymes catalyzing reciprocal reactions in the melanin biosynthesis pathway, also affect cuticular hydrocarbon (CHC) composition in D. melanogaster females. Hydrocarbons 182-193 ebony Drosophila melanogaster 55-60 30733060-1 2019 In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene synthases is typically carried out by cytochrome P450 oxygenases (CYPs). Hydrocarbons 48-59 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 127-142 31011633-8 2019 It is demonstrated that the change in hydrophobic tail length by two hydrocarbons drastically changed a cellular entry route and potency in activating the NLRP3 inflammasomes. Hydrocarbons 69-81 NLR family pyrin domain containing 3 Homo sapiens 155-160 30888173-7 2019 TRS benzenoid hydrocarbons are those isomers in benzenoids having their number of formula carbons divisible by six and a maximum number of perimeter bay regions (etao) given by eta0(TRS) = (1/2) NH(sextet) - 3 + F. NH(sextet) is the number of formula hydrogens and F is the number of perimeter fjords (triplet of adjacent bay regions); for strain-free TRS benzenoids, F = 0. Hydrocarbons 14-26 tRNA-Ser (anticodon TGA) 2-1 Homo sapiens 177-193 30357195-5 2019 This review showcases recent advances in the solar-driven COx reduction to hydrocarbons over 2D-based materials. Hydrocarbons 75-87 cytochrome c oxidase subunit 8A Homo sapiens 58-61 31079636-8 2019 The liquid products composed of broad range of C2 - C15 hydrocarbons depending on the pyrolytic parameters. Hydrocarbons 56-68 placenta associated 8 Homo sapiens 52-55 30377198-0 2019 Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis. Hydrocarbons 114-125 indoleamine 2,3-dioxygenase 1 Homo sapiens 12-15 30659730-1 2019 The high-valence iron species (Fe(IV)=O) in the cytochrome P450 enzyme superfamily is generated via the activation of O2 , and serves as the active center of selective hydrocarbon oxidation reactions. Hydrocarbons 168-179 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 59-63 30610181-6 2019 Next, using an RNA interference screen, fluorescence correlation spectroscopy, and confocal imaging, we identify VPS39-a gene encoding a subunit of the homotypic fusion and protein-sorting (HOPS) complex-as a critical determinant in the trafficking of CPMPs and hydrocarbon-stapled peptides to the cytosol. Hydrocarbons 262-273 VPS39 subunit of HOPS complex Homo sapiens 113-118 30816187-4 2019 The X-ray micro-spectroscopic technique revealed that the OM aggregate has sp2 dominated hydrocarbon networks with a lower abundance of heteroatoms than in IOM from primitive (CI,CM,CR) carbonaceous chondrites, and thus it is distinguished from most of the OM in carbonaceous meteorites. Hydrocarbons 89-100 Sp2 transcription factor Homo sapiens 75-78 30512233-7 2019 In silico calculations strongly suggest that the carbonyl group of these oxygenated hydrocarbons interacts with both Asn319 and Ala39 at the subunit A of ODC1. Hydrocarbons 84-96 ornithine decarboxylase 1 Homo sapiens 154-158 30675992-0 2019 Effects of offshore oil exploration and development in the Alaskan Beaufort Sea: Long-term patterns of hydrocarbons in sediments. Hydrocarbons 103-115 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 76-79 30675992-8 2019 The hydrocarbons in the Beaufort Sea sediments are primarily from non-oil petrogenic and biogenic sources, with small amounts of pyrogenic hydrocarbons. Hydrocarbons 4-16 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 33-36 30675992-8 2019 The hydrocarbons in the Beaufort Sea sediments are primarily from non-oil petrogenic and biogenic sources, with small amounts of pyrogenic hydrocarbons. Hydrocarbons 139-151 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 33-36 30675992-9 2019 Most of the hydrocarbons are carried to the Beaufort Sea in coastal erosion and river inputs of hydrocarbon-rich materials, such as peat and shale. Hydrocarbons 12-24 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 53-56 30675992-9 2019 Most of the hydrocarbons are carried to the Beaufort Sea in coastal erosion and river inputs of hydrocarbon-rich materials, such as peat and shale. Hydrocarbons 12-23 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 53-56 30796595-0 2019 Assessing the ecological risks from hydrocarbons in the marine coastal sediments of Jeddah, Red Sea. Hydrocarbons 36-48 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 96-99 30554387-4 2019 In this review, the genes involved in the biodegradation of hydrocarbons and several emerging plasticizer compounds in Rhodococcus strains are described in detail (aliphatic, aromatics, PAH, phthalate, polyethylene, and polyisoprene). Hydrocarbons 60-72 phenylalanine hydroxylase Homo sapiens 186-189 30554999-4 2019 Rather, dHNF4 directs their conversion to very long chain fatty acids and hydrocarbons, which waterproof the animal to preserve fluid homeostasis. Hydrocarbons 74-86 Hepatocyte nuclear factor 4 Drosophila melanogaster 8-13 30312624-5 2018 We demonstrate that oenocyte-specific reduction of desaturase activity is sufficient to dramatically alter the composition of the hydrocarbon mix displayed by the flies. Hydrocarbons 130-141 Desaturase 1 Drosophila melanogaster 51-61 30881679-0 2019 Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein. Hydrocarbons 63-74 eukaryotic translation initiation factor 4E Homo sapiens 104-147 30881679-2 2019 We have used a structure-guided approach to rationally develop a set of hydrocarbon stapled-peptides with high binding affinities and residence times against the oncogenic eukaryotic translation initiation factor 4E (eIF4E) protein. Hydrocarbons 72-83 eukaryotic translation initiation factor 4E Homo sapiens 172-215 30881679-2 2019 We have used a structure-guided approach to rationally develop a set of hydrocarbon stapled-peptides with high binding affinities and residence times against the oncogenic eukaryotic translation initiation factor 4E (eIF4E) protein. Hydrocarbons 72-83 eukaryotic translation initiation factor 4E Homo sapiens 217-222 30881679-5 2019 The interactions were further exploited by designing features in the peptides to attenuate disorder and increase helicity which collectively resulted in the generation of a distinct class of hydrocarbon stapled-peptides targeting eIF4E. Hydrocarbons 191-202 eukaryotic translation initiation factor 4E Homo sapiens 230-235 30422643-5 2018 On the basis of this strategy, we show that >95% of initial hydrocarbon production activity can be maintained for 12 h in KHCO3 (99% purity) enriched distilled water and 6 h in KHCO3 (99% purity) enriched tap water. Hydrocarbons 63-74 SEC14 like lipid binding 2 Homo sapiens 208-211 29990597-8 2018 Insertion of the myristoyl group of recoverin into the membrane is connected with an increase in the tilt of the hydrocarbon chains with respect to the surface normal and decrease in the bilayer thickness. Hydrocarbons 113-124 recoverin Homo sapiens 36-45 30144681-5 2018 Secondly, porous alumina bed materials could absorb more gaseous hydrocarbon and prolong the residence time of hydrocarbon in the diluted zone of FBC due to its higher BET. Hydrocarbons 111-122 delta/notch like EGF repeat containing Homo sapiens 168-171 30503619-7 2018 We found that one of these, the fatty acid elongase eloF, broadly affects the hydrocarbons present on D. sechellia and D. melanogaster females, as well as the propensity of D. simulans males to mate with them. Hydrocarbons 78-90 elongase F Drosophila melanogaster 52-56 32254745-4 2018 In contrast, GGT catalyzed cascade reactions including cleavage of the gamma-glutamyl group and subsequent aromatic hydrocarbon transfer from the S to N atom increased the distance between the two chromophores, thus decreasing the FRET efficiency, with the recovery of the donor fluorescence at 461 nm. Hydrocarbons 116-127 gamma-glutamyltransferase light chain 5 pseudogene Homo sapiens 13-16 30053377-0 2018 SN2 Reactions in Hydrocarbon Solvents Using Ammonium-Terminated Polyisobutylene Oligomers as Phase-Solubilizing Agents and Catalysts. Hydrocarbons 17-28 solute carrier family 38 member 5 Homo sapiens 0-3 30320850-4 2018 Hydrophobic polymer coatings have been widely used to concentrate hydrocarbons for attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) detection at the surface of an ATR crystal by preventing water molecules from penetrating into the polymer coating while absorbing hydrocarbons. Hydrocarbons 66-78 ATR serine/threonine kinase Homo sapiens 152-155 30320850-4 2018 Hydrophobic polymer coatings have been widely used to concentrate hydrocarbons for attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) detection at the surface of an ATR crystal by preventing water molecules from penetrating into the polymer coating while absorbing hydrocarbons. Hydrocarbons 66-78 ATR serine/threonine kinase Homo sapiens 193-196 30320850-4 2018 Hydrophobic polymer coatings have been widely used to concentrate hydrocarbons for attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) detection at the surface of an ATR crystal by preventing water molecules from penetrating into the polymer coating while absorbing hydrocarbons. Hydrocarbons 293-305 ATR serine/threonine kinase Homo sapiens 152-155 30320850-4 2018 Hydrophobic polymer coatings have been widely used to concentrate hydrocarbons for attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) detection at the surface of an ATR crystal by preventing water molecules from penetrating into the polymer coating while absorbing hydrocarbons. Hydrocarbons 293-305 ATR serine/threonine kinase Homo sapiens 193-196 30320850-5 2018 However, in typical coating designs only thin films (<5 mum) can be applied onto the ATR sensor due to the decrease in detection limit and sensitivity to hydrocarbons with increasing film thickness. Hydrocarbons 157-169 ATR serine/threonine kinase Homo sapiens 88-91 30320850-6 2018 This paper demonstrates that a semi-crystalline linear low-density polyethylene (LLDPE) polymer coating with thicker thickness (40 mum) can be applied effectively for in situ ATR-FTIR detection of hydrocarbons in aqueous solution. Hydrocarbons 197-209 ATR serine/threonine kinase Homo sapiens 175-178 30320850-7 2018 The ATR signal is enhanced by the polymer coating which swells in response to the hydrocarbons and prevents water accumulation at the IR detection interface. Hydrocarbons 82-94 ATR serine/threonine kinase Homo sapiens 4-7 30320850-8 2018 Coating the ATR element with a LLDPE film (crystallinity = 12%) reduced the detection time for various hydrocarbons, including toluene, benzene and chloroform. Hydrocarbons 103-115 ATR serine/threonine kinase Homo sapiens 12-15 28820043-1 2018 Water contamination with chlorinated hydrocarbons such as chloroform (CHCl3), carbon tetrachloride (CCl4) and trichloroethylene (TCE) is one of the major public health concerns. Hydrocarbons 37-49 C-C motif chemokine ligand 4 Homo sapiens 100-104 30243802-4 2018 The results of the work reported herein demonstrate that CYP4G55 and CYP4G56 from the mountain pine beetle, Dendroctonus ponderosae, expressed as fusion proteins with house fly cytochrome P450 reductase (CPR), convert both long chain aldehydes and long chain alcohols to hydrocarbons. Hydrocarbons 271-283 NADPH--cytochrome P450 reductase Musca domestica 177-202 30243802-4 2018 The results of the work reported herein demonstrate that CYP4G55 and CYP4G56 from the mountain pine beetle, Dendroctonus ponderosae, expressed as fusion proteins with house fly cytochrome P450 reductase (CPR), convert both long chain aldehydes and long chain alcohols to hydrocarbons. Hydrocarbons 271-283 NADPH--cytochrome P450 reductase Musca domestica 204-207 29896786-8 2018 Together, these findings confirm the involvement of CYP4G11 in cuticular hydrocarbon production and suggest a possible role in clearing pheromonal and phytochemical compounds from antennae. Hydrocarbons 73-84 cytochrome P450 4G11 Apis mellifera 52-59 29896786-9 2018 This possible dual functionality of CYP4G11, i.e., cuticular hydrocarbon and comb wax production and antennal odorant clearance, may explain how honey bees function with a reduced CYP4G inventory. Hydrocarbons 61-72 cytochrome P450 4G11 Apis mellifera 36-43 30486471-1 2018 To improve the strength and maintain the inherent properties of flame-retardant polyacrylonitrile (FR-PAN) fiber, a commercialized hydrocarbon polymer, i.e., poly (vinyl alcohol) (PVA), used as an enhancement component, was blended with polyacrylonitrile (PAN) spinning dope to fabricate a PVA/PAN composite fiber through wet-spun technology. Hydrocarbons 131-142 adenosine deaminase 2 Homo sapiens 102-105 30272965-6 2018 Additionally, positive trends in activation of some of the molecular targets (e.g., PXR) with increasing NVDOC concentrations (including polar transformation products) demonstrate the importance of improving our understanding of the toxicity associated with the unknown transformation products present in hydrocarbon-impacted waters. Hydrocarbons 305-316 nuclear receptor subfamily 1 group I member 2 Homo sapiens 84-87 30320850-0 2018 Improved ATR-FTIR detection of hydrocarbons in water with semi-crystalline polyolefin coatings on ATR elements. Hydrocarbons 31-43 ATR serine/threonine kinase Homo sapiens 9-12 30320850-0 2018 Improved ATR-FTIR detection of hydrocarbons in water with semi-crystalline polyolefin coatings on ATR elements. Hydrocarbons 31-43 ATR serine/threonine kinase Homo sapiens 98-101 30351139-2 2018 Fischer-Tropsch catalysis produces energy dense liquid hydrocarbons from synthesis gas (CO and H2) and has been a mainstay of the energy economy since its discovery nearly a century ago. Hydrocarbons 55-67 relaxin 2 Homo sapiens 88-97 30071415-1 2018 An onshore radiometric survey sampled in situ the isotopes U238, Th232, K40, and Rn222 to build maps of normalized values for each element containing negative and positive radiometric anomalies, which could associate with hydrocarbon deposits in the subsoil. Hydrocarbons 222-233 keratin 40 Homo sapiens 72-75 30053377-4 2018 Based on these studies, we developed a solid/liquid catalytic process using insoluble alkali metal carboxylate salts and a recyclable soluble polyisobutylene-bound catalyst that can be used to carry out SN2 reactions both in heptane and in hydrocarbon oligomeric solvents known as poly(alpha-olefins) (PAOs). Hydrocarbons 240-251 solute carrier family 38 member 5 Homo sapiens 203-206 30035527-18 2018 These insights suggest that the RTA activity of organosulfur compounds may be as important to the inhibition of hydrocarbon autoxidation, if not more so, than their ionic reactions. Hydrocarbons 112-123 MAS related GPR family member F Homo sapiens 32-35 29859459-6 2018 Several chlorinated hydrocarbons are evaluated as the reagent chemicals for providing Cl- reactant ions, of which CCl4 is identified as the best ionizing reagent. Hydrocarbons 20-32 C-C motif chemokine ligand 4 Homo sapiens 114-118 30032608-5 2018 The barrierless nature of this reaction scheme suggests the 1-propynyl radical may be a key intermediate in hydrocarbon chain growth in cold molecular clouds like TMC-1, where methyl-substituted (poly)acetylenes are known to exist. Hydrocarbons 108-119 transmembrane channel like 1 Homo sapiens 163-168 29687314-3 2018 It was determined that in the microbial cell on media with hydrocarbons, the generation of superoxide anion radical increases, accumulation of hydrogen peroxide and induction of superoxide dismutase synthesis occur, and catalase activity is reduced. Hydrocarbons 59-71 catalase Achromobacter xylosoxidans 220-228 29752518-4 2018 However, most of the ARHD diversity studies are based on the PAH degraders and the ARHD diversity in the monoaromatic hydrocarbon degraders has not fully explored yet. Hydrocarbons 118-129 ras homolog family member D Homo sapiens 83-87 29752518-5 2018 In this study, therefore, the ARHD gene from nine different genara of the monoaromatic hydrocarbon degraders including Raoultella, Stenotrophomons, Staphylococcus, Acinetobacter, Pseudomonas, Serratia, Comamonas, Pantoea, and Micrococcus was analysed through polymerase chain reactions and sequencing. Hydrocarbons 87-98 ras homolog family member D Homo sapiens 30-34 29928806-2 2018 Specifically, we have developed new transferable CG beads, which can be used to model the hydrocarbons (C5 to C17) and reproduce their experimental properties with good accuracy. Hydrocarbons 90-102 cytokine like 1 Homo sapiens 110-113 30028454-1 2018 The Fe(TPA) (TPA = tris(pyridyl-2-methyl)amine) class of non-haem Fe catalysts is proposed to carry out selective hydrocarbon oxidations through the generation of high-valent iron species. Hydrocarbons 114-125 plasminogen activator, tissue type Homo sapiens 4-11 30028454-1 2018 The Fe(TPA) (TPA = tris(pyridyl-2-methyl)amine) class of non-haem Fe catalysts is proposed to carry out selective hydrocarbon oxidations through the generation of high-valent iron species. Hydrocarbons 114-125 plasminogen activator, tissue type Homo sapiens 7-10 29653326-4 2018 In LE-WAFs, the Microtox EC50 was associated with biodegradation of the predominant hydrocarbons (naphthalenes, 2- to 3-ring PAH), as well as with phenol degradation products. Hydrocarbons 84-96 phenylalanine hydroxylase Homo sapiens 125-128 29499181-5 2018 Long-tailed analogues (C16, C18) are cohesively integrated into DPPC monolayers due to their smaller cone angles at the interfacial region and increased hydrocarbon compatibility in the hydrophobic region. Hydrocarbons 153-164 Bardet-Biedl syndrome 9 Homo sapiens 28-31 29771459-2 2018 The influence of the solvent (HCN, CH2 Cl2 , and aromatic hydrocarbons) on the crystallization process was studied, revealing dimer formation when using HCN or CH2 Cl2 as solvent, whereas aromatic hydrocarbons led to the formation of monomeric arene HCN-B(C6 F5 )3 adducts, additionally stabilized by eta6 -coordination of the aromatic ring system similar to well-known half-sandwich complexes. Hydrocarbons 58-70 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 153-156 29771459-2 2018 The influence of the solvent (HCN, CH2 Cl2 , and aromatic hydrocarbons) on the crystallization process was studied, revealing dimer formation when using HCN or CH2 Cl2 as solvent, whereas aromatic hydrocarbons led to the formation of monomeric arene HCN-B(C6 F5 )3 adducts, additionally stabilized by eta6 -coordination of the aromatic ring system similar to well-known half-sandwich complexes. Hydrocarbons 58-70 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 153-156 29961775-1 2018 A new strategy to design new molecules based on a fused hydrocarbon ring system comprising a COT ring and two 5-membered rings has been proposed for the study of second order NLO properties. Hydrocarbons 56-67 mitogen-activated protein kinase kinase kinase 8 Homo sapiens 93-96 29487133-5 2018 We found that the most potent BLVRB inhibitors contain a tricyclic hydrocarbon core structure similar to the isoalloxazine ring of flavin mononucleotide and that both xanthene- and acridine-based compounds inhibit BLVRB"s flavin and dichlorophenolindophenol (DCPIP) reductase functions. Hydrocarbons 67-78 biliverdin reductase B Homo sapiens 30-35 29747152-3 2018 The total hydrocarbon (TPHs) concentration in WAF was 2.18 mg L-1. Hydrocarbons 10-21 L1 cell adhesion molecule Homo sapiens 62-65 29747152-4 2018 The dissipation rates of hydrocarbons in WAF showed a first-order kinetics, with half-lives ranging between 65 h-200 h. Amphipods from LB showed acute and chronic LC50 values of 0.33 and 0.018 mg L-1, respectively. Hydrocarbons 25-37 L1 cell adhesion molecule Homo sapiens 196-199 29272834-1 2018 The Mediterranean Sea is one of the busiest areas worldwide in terms of maritime activity, facing considerable anthropogenic disturbance, such as pollution by hydrocarbons and heavy metals. Hydrocarbons 159-171 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 18-21 29740643-1 2018 We present a microwave spectral taxonomy study of several hydrocarbon/CS2 discharge mixtures in which more than 60 distinct chemical species, their more abundant isotopic species, and/or their vibrationally excited states were detected using chirped-pulse and cavity Fourier-transform microwave spectroscopies. Hydrocarbons 58-69 chorionic somatomammotropin hormone 2 Homo sapiens 70-73 29890613-8 2018 The selection of the sampling points was based on the results revealed by the PSG survey that showed significant quantities of analyzed organic hydrocarbon for a follow-up investigation. Hydrocarbons 144-155 pregnancy specific beta-1-glycoprotein 5 Homo sapiens 78-81 29277655-11 2018 Phosphatidylserine, a phospholipid whose hydrocarbon tails contain stearic and oleic acids also inhibits TMEM16A. Hydrocarbons 41-52 anoctamin 1 Homo sapiens 105-112 29978130-0 2018 Relationship Between the Content of Chlorinated Hydrocarbons and Fatty Acid Composition of Milk Fat. Hydrocarbons 48-60 Weaning weight-maternal milk Bos taurus 91-95 29330430-2 2018 Using an L-cysteine-based hydrothermal process, here we synthesize a carbon-doped SnS2 (SnS2-C) metal dichalcogenide nanostructure, which exhibits a highly active and selective photocatalytic conversion of CO2 to hydrocarbons under visible-light. Hydrocarbons 213-225 sodium voltage-gated channel alpha subunit 11 Homo sapiens 82-86 29434193-1 2018 Measuring gravity from an aircraft or a ship is essential in geodesy, geophysics, mineral and hydrocarbon exploration, and navigation. Hydrocarbons 94-105 inositol polyphosphate-5-phosphatase D Homo sapiens 40-44 29339518-5 2018 Critical to the design of effective inhibitors was our introduction of an all-hydrocarbon cross-link or "staple" that stabilizes alpha-helical structure, increases target binding affinity, and independently confers binding specificity for Mcl-1 over related Bcl-2 family paralogs. Hydrocarbons 78-89 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 239-244 29339518-5 2018 Critical to the design of effective inhibitors was our introduction of an all-hydrocarbon cross-link or "staple" that stabilizes alpha-helical structure, increases target binding affinity, and independently confers binding specificity for Mcl-1 over related Bcl-2 family paralogs. Hydrocarbons 78-89 BCL2 apoptosis regulator Homo sapiens 258-263 29462874-1 2018 Highly selective C(sp2)-C(sp2) cross-coupling of dihalogenated hydrocarbons comprising C(sp2)-Br and C(sp3)-Cl bonds with arylboronic acids is reported. Hydrocarbons 63-75 Sp2 transcription factor Homo sapiens 17-22 29462874-1 2018 Highly selective C(sp2)-C(sp2) cross-coupling of dihalogenated hydrocarbons comprising C(sp2)-Br and C(sp3)-Cl bonds with arylboronic acids is reported. Hydrocarbons 63-75 Sp2 transcription factor Homo sapiens 24-29 29462874-1 2018 Highly selective C(sp2)-C(sp2) cross-coupling of dihalogenated hydrocarbons comprising C(sp2)-Br and C(sp3)-Cl bonds with arylboronic acids is reported. Hydrocarbons 63-75 Sp2 transcription factor Homo sapiens 24-29 29330430-2 2018 Using an L-cysteine-based hydrothermal process, here we synthesize a carbon-doped SnS2 (SnS2-C) metal dichalcogenide nanostructure, which exhibits a highly active and selective photocatalytic conversion of CO2 to hydrocarbons under visible-light. Hydrocarbons 213-225 sodium voltage-gated channel alpha subunit 11 Homo sapiens 88-94 29073567-2 2018 The efficacy of FLT in the clean-up of hydrocarbon-contaminated soils is well established at the field-scale. Hydrocarbons 39-50 fms related receptor tyrosine kinase 1 Homo sapiens 16-19 29136337-0 2018 Production of Jet Fuel-Range Hydrocarbons from Hydrodeoxygenation of Lignin over Super Lewis Acid Combined with Metal Catalysts. Hydrocarbons 29-41 F-box and leucine rich repeat protein 15 Homo sapiens 14-17 29136337-3 2018 Near theoretical yields of hydrocarbons were produced from lignin model compounds by the combined catalysis of Hf(OTf)4 and ruthenium-based catalysts. Hydrocarbons 27-39 POU class 5 homeobox 1 Homo sapiens 114-119 29136337-4 2018 When a technical lignin derived from a pilot-scale biorefinery was used, more than 30 wt % of the hydrocarbons produced with this catalytic system were cyclohexane and alkylcyclohexanes in the jet fuel range. Hydrocarbons 98-110 F-box and leucine rich repeat protein 15 Homo sapiens 193-196 28942192-1 2017 Emissions due to ship-loading of hydrocarbons are currently not addressed neither by the Directive on the integrated pollution prevention or by other environmental regulations. Hydrocarbons 33-45 inositol polyphosphate-5-phosphatase D Homo sapiens 17-21 29040835-5 2018 This shows that PSO4 is capable of disordering the hydrocarbon chains of PC efficiently. Hydrocarbons 51-62 pre-mRNA processing factor 19 Homo sapiens 16-20 28702706-6 2018 In accordance, biomarker genes for anaerobic hydrocarbon degradation (bamA, ebdA, bcrA, and bssA) were prevalent, only outnumbered by alkB, and their sequences were taxonomically binned to the same bacterial groups. Hydrocarbons 45-56 alkB homolog 1, histone H2A dioxygenase Homo sapiens 134-138 29141146-1 2017 Attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy using a polymer coated internal reflection element/waveguide is an established sensor platform for the detection of a range of organic and hydrocarbon molecules dissolved in water. Hydrocarbons 219-230 ATR serine/threonine kinase Homo sapiens 57-60 28081667-0 2018 Contributions of caspase-8 and -9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons. Hydrocarbons 98-110 caspase 8 Homo sapiens 17-33 28081667-0 2018 Contributions of caspase-8 and -9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons. Hydrocarbons 98-110 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 55-61 28081667-13 2018 CYP2E1-inducing compounds play a pivotal role in halogenated hydrocarbon toxicity. Hydrocarbons 61-72 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 0-6 28917649-2 2017 Three new 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-linker-d-Phe-(d-Lys6-GnRH) peptides with different hydrocarbon linkers were designed to evaluate their effects on GnRH receptor binding affinities. Hydrocarbons 125-136 gonadotropin releasing hormone 1 Homo sapiens 95-99 28940713-1 2017 Equipped with excellent hydrocarbon solubility, the lithium hydride surrogate 1-lithium-2-tert-butyl-1,2-dihydropyridine (1tLi) functions as a precatalyst to convert Me2 NH BH3 to [NMe2 BH2 ]2 (89 % conversion) under competitive conditions (2.5 mol %, 60 h, 80 C, toluene solvent) to that of previously reported LiN(SiMe3 )2 . Hydrocarbons 24-35 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 181-185 28815973-5 2017 GaPd2 is shown to be the first binary catalyst material, which shows a positive reaction order (0.89) with respect to acetylene at 200 C. The influences on the extent of acetylene conversion, specific activity and selectivity to ethylene, ethane, and higher hydrocarbons are determined by a 24 factorial experiment following a design of experiments approach. Hydrocarbons 259-271 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Homo sapiens 0-5 31457248-1 2017 Recently, the decarboxylation of oleic acid (9(Z)-octadecenoic acid) catalyzed by triruthenium dodecacarbonyl, Ru3(CO)12, to give a mixture of heptadecenes with concomitant formation of other hydrocarbons, heptadecane and C17 alkylbenzenes, was reported. Hydrocarbons 192-204 cytokine like 1 Homo sapiens 222-225 28939823-2 2017 Here we report the development of all-hydrocarbon stabilized peptides derived from the RAB-binding FIP-family of proteins to target RAB25. Hydrocarbons 38-49 RAB25, member RAS oncogene family Homo sapiens 132-137 29242470-9 2017 nov. is the second report of an occurrence of this genus at hydrocarbon seeps (both of which come from the Paleo-Barents Sea). Hydrocarbons 60-71 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 121-124 28342286-5 2017 In both cases, Aurora-A is trapped through interaction with a synthetic protein, either a single-domain antibody that inhibits the kinase or a hydrocarbon-stapled peptide that activates the kinase. Hydrocarbons 143-154 aurora kinase A Homo sapiens 15-23 28585773-3 2017 Here we report an electric-stimuli-responsive multifunctional material, [10]CPP-I: crystalline assembly of a hydrocarbon nanoring ([10]cycloparaphenylene: [10]CPP) as an "electro-responsive porous host" and iodine as a "potentially functional molecule". Hydrocarbons 109-120 cathepsin C Homo sapiens 76-81 28752254-3 2017 The bend and kink effects from the cis-double bond(s) in the hydrocarbon chain affected the membrane fluidity and molecular packing in the monolayers, which resulted in a greater interaction between unsaturated C18 fatty acids and DP. Hydrocarbons 61-72 Bardet-Biedl syndrome 9 Homo sapiens 211-214 28756661-3 2017 Pt7, of the three sizes studied, is the most active and, therefore, like many other catalysts, deactivates by coking during reactions in hydrocarbon-rich environments. Hydrocarbons 137-148 zinc finger protein 79 Homo sapiens 0-3 28098246-6 2017 Analysis of the promoter region of IL-10R1 revealed a functional aryl hydrocarbon response element, which is induced by Kyn in luciferase-based IL-10R1 promoter assays. Hydrocarbons 70-81 interleukin 10 receptor, alpha Mus musculus 35-42 28098246-6 2017 Analysis of the promoter region of IL-10R1 revealed a functional aryl hydrocarbon response element, which is induced by Kyn in luciferase-based IL-10R1 promoter assays. Hydrocarbons 70-81 interleukin 10 receptor, alpha Mus musculus 144-151 28669634-1 2017 Cyanobacteria and plants synthesize carotenoids via a poly-cis pathway starting with phytoene, a membrane-bound C40 hydrocarbon. Hydrocarbons 116-127 CCR4-NOT transcription complex subunit 11 Homo sapiens 112-115 28556602-4 2017 These aryl-type radical additions to conjugated hydrocarbons via resonantly stabilized free-radical intermediates defy conventional wisdom that PAH growth is predominantly a high-temperature phenomenon and thus may represent an overlooked path to PAHs as complex as coronene and corannulene in cold regions of the interstellar medium like in the Taurus Molecular Cloud. Hydrocarbons 48-60 phenylalanine hydroxylase Homo sapiens 144-147 28597527-1 2017 We report an investigation of interfacial fluorinated hydrocarbon (carboxylic-fantrip) monolayers by nanoscale imaging using tip-enhanced Raman spectroscopy (TERS) and density functional theory (DFT) calculations. Hydrocarbons 54-65 TOR signaling pathway regulator Homo sapiens 125-128 29964629-3 2017 The results indicated that main DBP precursors in sewage were humic acid and aliphatic hydrocarbons, and were mainly dominated by HPI. Hydrocarbons 87-99 D-box binding PAR bZIP transcription factor Homo sapiens 32-35 28720804-3 2017 We have investigated the abiogenic synthesis of hydrocarbon systems at pressures of 2.0-6.6 GPa and temperatures of 250-600 C. The determined lower thermobaric limit of the reaction at 280-300 C and 2-3 GPa corresponds to a depth of 70-80 km during cold subduction. Hydrocarbons 48-59 glycophorin A (MNS blood group) Homo sapiens 92-95 28720804-3 2017 We have investigated the abiogenic synthesis of hydrocarbon systems at pressures of 2.0-6.6 GPa and temperatures of 250-600 C. The determined lower thermobaric limit of the reaction at 280-300 C and 2-3 GPa corresponds to a depth of 70-80 km during cold subduction. Hydrocarbons 48-59 glycophorin A (MNS blood group) Homo sapiens 205-208 28195409-1 2017 Isolable dialkylsilylene 5 reacts with dihydrogen in the presence of a small amount of a conventional Lewis acid (BPh3 , BEt3 ) or a base (PPh3 , PEt3 , NPh3 , NEt3 ) at low temperatures in a hydrocarbon solvent, giving the corresponding dihydrosilane 10 in high yields. Hydrocarbons 192-203 tetraspanin 2 Homo sapiens 160-164 28235184-9 2017 The gene copy numbers of 16S rRNA and 2 hydrocarbon-degrading genes (CYP153 and alkB) were significantly affected (p < 0.05) by the interaction of plant species and sampling location. Hydrocarbons 40-51 alkB homolog 1, histone H2A dioxygenase Homo sapiens 80-84 28616938-0 2017 Construction of an all-solid-state artificial Z-scheme system consisting of Bi2WO6/Au/CdS nanostructure for photocatalytic CO2 reduction into renewable hydrocarbon fuel. Hydrocarbons 152-163 CDP-diacylglycerol synthase 1 Homo sapiens 86-89 28259688-6 2017 Substitution of the disrupted epidermal lipid barrier by an inert hydrocarbon coat prevents excessive transepidermal water loss, normalizes thermogenesis and metabolic parameters, and surprisingly leads to the activation of hair bulge progenitor cells and reprograming of a regular hair growth cycle and development of a regular fur in scd1-/- mice. Hydrocarbons 66-77 stearoyl-Coenzyme A desaturase 1 Mus musculus 336-340 28513661-0 2017 A zwitterionic hydrocarbon-soluble borenium ion based on a beta-diketiminate backbone. Hydrocarbons 15-26 amyloid beta precursor protein Homo sapiens 57-63 28513668-4 2017 However, it was observed that the gas-phase results did not replicate selective C-H hydroxylation observed experimentally when CAT1 catalyzed hydrocarbon oxidations by H2O2via an HO-FeV[double bond, length as m-dash]O oxidant (CAT1a). Hydrocarbons 142-153 GIT ArfGAP 1 Homo sapiens 127-131 28409927-3 2017 Application of the one-dimensional aggregate theory to the SANS results led to the conclusion that the existence of a limiting size also depended on the length of the main long-hydrocarbon chain and affected strongly the dynamic behavior of the aggregates, causing breakage of thread-like micelles or ribbon-like aggregates. Hydrocarbons 177-188 USH1 protein network component sans Homo sapiens 59-63 29693997-4 2017 Practically full conversion of hydrocarbons was achieved already with 1 mass.% of platinum in the Pt/Al2O3 catalyst with sub-mum- and nm-sized particles placed at the input of the gas-air mixture into the channel of the permeable thermoelement. Hydrocarbons 31-43 latexin Homo sapiens 125-128 28004185-3 2017 The enzymatic conversion of Cn chain length fatty aldehydes (or acids) to Cn-1 hydrocarbons, alkanes or alkenes, involves a C-C scission reaction. Hydrocarbons 79-91 5'-nucleotidase, cytosolic IA Homo sapiens 74-78 27935715-9 2017 On hydrophobic hydrocarbon surfaces, fibrillation is retarded but not completely suppressed, in contrast to previous observations for full-length hIAPP(1-37). Hydrocarbons 15-26 islet amyloid polypeptide Homo sapiens 146-151 28090721-3 2017 This activated HOF-TCBP has a high BET surface area of 2066 m2 g-1 and is capable of highly selective adsorption and separation of light hydrocarbons under ambient conditions. Hydrocarbons 138-150 TIA1 cytotoxic granule associated RNA binding protein like 1 Homo sapiens 19-23 28090721-3 2017 This activated HOF-TCBP has a high BET surface area of 2066 m2 g-1 and is capable of highly selective adsorption and separation of light hydrocarbons under ambient conditions. Hydrocarbons 138-150 delta/notch like EGF repeat containing Homo sapiens 35-38 28265508-8 2017 The root exudates included hundreds of specific organic matter types; hydrocarbon, total sugar, total amino acids, and phenolic compounds were crucial to the AES. Hydrocarbons 70-81 TLE family member 5, transcriptional modulator Homo sapiens 158-161 27990813-0 2016 Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons. Hydrocarbons 56-68 cytochrome c, somatic Homo sapiens 0-12 27990813-4 2016 We present three structures at 1.7-2.0 A resolution of a domain-swapped dimer of yeast iso-1-cytochrome c with the detergents, CYMAL-5, CYMAL-6, and omega-undecylenyl-beta-d-maltopyranoside, bound in a channel that places the hydrocarbon moieties of these detergents next to the heme. Hydrocarbons 226-237 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 87-92 27990813-4 2016 We present three structures at 1.7-2.0 A resolution of a domain-swapped dimer of yeast iso-1-cytochrome c with the detergents, CYMAL-5, CYMAL-6, and omega-undecylenyl-beta-d-maltopyranoside, bound in a channel that places the hydrocarbon moieties of these detergents next to the heme. Hydrocarbons 226-237 cytochrome c, somatic Homo sapiens 93-105 27990813-8 2016 The well-defined hydrocarbon binding pocket provides atomic resolution evidence for the extended lipid anchorage model for cytochrome c/cardiolipin binding. Hydrocarbons 17-28 cytochrome c, somatic Homo sapiens 123-135 27990813-10 2016 However, the dimer structure shows that only a modest deformation of monomeric cytochrome c would suffice to form the hydrocarbon binding site occupied by these detergents. Hydrocarbons 118-129 cytochrome c, somatic Homo sapiens 79-91 27775325-0 2016 A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix. Hydrocarbons 63-74 TPX2 microtubule nucleation factor Homo sapiens 2-6 27775325-0 2016 A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix. Hydrocarbons 63-74 aurora kinase A Homo sapiens 47-55 27794461-0 2016 Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity. Hydrocarbons 24-35 Desaturase 1 Drosophila melanogaster 121-131 27809529-0 2016 Spin-Delocalization in a Helical Open-Shell Hydrocarbon. Hydrocarbons 44-55 spindlin 1 Homo sapiens 0-4 27809529-3 2016 Here, we examine the prospect of extending spin-delocalization over a helical backbone in a model compound naphtho[3,2,1-no]tetraphene, the first helically chiral open-shell hydrocarbon, in which one benzene ring is fused to [5]helicene, forming a phenalenyl subunit. Hydrocarbons 174-185 spindlin 1 Homo sapiens 43-47 30974703-4 2016 In this respect, we report on the synthesis and characterization of polysarcosine based lipids with C14 and C18 hydrocarbon chains and their end group functionalization. Hydrocarbons 112-123 Bardet-Biedl syndrome 9 Homo sapiens 108-111 27763736-3 2016 No reaction occurred when 8 was treated with CsF in a hydrocarbon solvent. Hydrocarbons 54-65 colony stimulating factor 2 Homo sapiens 45-48 27732914-1 2016 Exposure to the halogenated hydrocarbon carbon tetrachloride (CCl4) leads to hepatic lipid peroxidation, inflammation and fibrosis. Hydrocarbons 28-39 chemokine (C-C motif) ligand 4 Mus musculus 62-66 27898012-3 2016 The MgF2-supported palladium with relatively large metal particles appeared the best catalyst, characterized by good activity and selectivity to C2-C5 hydrocarbons. Hydrocarbons 151-163 signal transducer and activator of transcription 5A Homo sapiens 4-7 27766836-5 2016 Here, we synthesize well-defined Co(II) ions on a silica surface using a metal siloxide precursor followed by thermal treatment under vacuum at 500 C. We show that these isolated Co(II) sites are catalysts for a number of hydrocarbon conversion reactions, such as the dehydrogenation of propane, the hydrogenation of propene, and the trimerization of terminal alkynes. Hydrocarbons 223-234 mitochondrially encoded cytochrome c oxidase II Homo sapiens 33-39 27766836-5 2016 Here, we synthesize well-defined Co(II) ions on a silica surface using a metal siloxide precursor followed by thermal treatment under vacuum at 500 C. We show that these isolated Co(II) sites are catalysts for a number of hydrocarbon conversion reactions, such as the dehydrogenation of propane, the hydrogenation of propene, and the trimerization of terminal alkynes. Hydrocarbons 223-234 mitochondrially encoded cytochrome c oxidase II Homo sapiens 180-186 27474998-2 2016 Exploration of the structure-activity relationship between the tpAIMs and KEAP1 is limited by the predominantly hydrocarbon nature of the oleanane triterpenoid pentacyclic ring structure. Hydrocarbons 112-123 kelch like ECH associated protein 1 Homo sapiens 74-79 27770652-3 2016 The presence of Cu+ species enables the stabilization of dimethyl ether, which efficiently suppresses the hydrocarbon formation during carbonylation process over Cu-H-MOR zeolite. Hydrocarbons 106-117 opioid receptor mu 1 Homo sapiens 167-170 27558663-4 2016 The change in mating behavior that results from inhibition of Obp56h expression is accompanied by significant alterations in cuticular hydrocarbon (CHC) composition, including reduction in 5-tricosene (5-T), an inhibitory sex pheromone produced by males that increases copulation latency during courtship. Hydrocarbons 135-146 Odorant-binding protein 56h Drosophila melanogaster 62-68 27498038-0 2016 Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity. Hydrocarbons 0-11 relaxin 3 Homo sapiens 41-50 27777648-0 2016 MIxS-HCR: a MIxS extension defining a minimal information standard for sequence data from environments pertaining to hydrocarbon resources. Hydrocarbons 117-128 coiled-coil alpha-helical rod protein 1 Homo sapiens 5-8 27777648-2 2016 The proposed MIxS-HCR package incorporates the core features of the MIxS standard for marker gene (MIMARKS) and metagenomic (MIMS) sequences along with a hydrocarbon resources customized environmental package. Hydrocarbons 154-165 coiled-coil alpha-helical rod protein 1 Homo sapiens 18-21 27777648-3 2016 Adoption of the MIxS-HCR standard will enable the comparison and better contextualization of investigations related to hydrocarbon rich environments. Hydrocarbons 119-130 coiled-coil alpha-helical rod protein 1 Homo sapiens 21-24 27573441-3 2016 Simultaneously, oxygenation was observed at other hydrocarbon chain positions (preferentially C2 and C11). Hydrocarbons 50-61 RNA polymerase III subunit K Homo sapiens 101-104 27578203-3 2016 This study shows that by manipulating a highly active acyl-CoA:diacylglycerol acyltransferase (DGAT) the hydrocarbon flux to oil in oilseeds can be increased without reducing the protein component. Hydrocarbons 105-116 diacylglycerol O-acyltransferase 1C Glycine max 54-93 27578203-3 2016 This study shows that by manipulating a highly active acyl-CoA:diacylglycerol acyltransferase (DGAT) the hydrocarbon flux to oil in oilseeds can be increased without reducing the protein component. Hydrocarbons 105-116 diacylglycerol O-acyltransferase 1C Glycine max 95-99 27586939-2 2016 Rotationally inelastic diffraction (RID) of H2 and D2 from this model hydrocarbon-decorated semiconductor interface has been confirmed for the first time via both time-of-flight and diffraction measurements, with modest j = 0 2 RID intensities for H2 compared to the strong RID features observed for D2 over a large range of kinematic scattering conditions along two high-symmetry azimuthal directions. Hydrocarbons 70-81 relaxin 2 Homo sapiens 44-53 27428812-0 2016 The Conversion of Starch and Sugars into Branched C10 and C11 Hydrocarbons. Hydrocarbons 62-74 RNA polymerase III subunit K Homo sapiens 58-61 27336293-0 2016 Air-water partition coefficients for a suite of polycyclic aromatic and other C10 through C20 unsaturated hydrocarbons. Hydrocarbons 106-118 homeobox C10 Homo sapiens 78-81 27216754-13 2016 Cholesterol decreases the partial free volume of the hydrocarbon region of the bilayer and thereby inhibits rhodopsin conformational changes required for activation. Hydrocarbons 53-64 rhodopsin Homo sapiens 108-117 27503057-4 2016 In the structural investigations of lipid bilayer"s response to Abeta binding, Small Angle Neutron Scattering and Neutron Membrane Diffraction revealed that the Abeta anchors firmly to the highly charged DMPG bilayers in the interfacial region between water and hydrocarbon chain, and it doesn"t penetrate deeply into the bilayer. Hydrocarbons 262-273 amyloid beta precursor protein Homo sapiens 161-166 27464307-0 2016 Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling. Hydrocarbons 78-89 relaxin 3 Homo sapiens 53-62 27464307-4 2016 The resulting hydrocarbon stapled peptide was shown by solution NMR spectroscopy to mimic the native helical conformation of relaxin-3 and to possess potent RXFP3 receptor binding and activation. Hydrocarbons 14-25 relaxin 3 Homo sapiens 125-134 27464307-4 2016 The resulting hydrocarbon stapled peptide was shown by solution NMR spectroscopy to mimic the native helical conformation of relaxin-3 and to possess potent RXFP3 receptor binding and activation. Hydrocarbons 14-25 relaxin family peptide receptor 3 Homo sapiens 157-162 27410737-6 2016 Both the osmotic-gradient and MD-simulation results indicated that AQP4 channel permeability decreased with decreasing bilayer hydrocarbon thickness. Hydrocarbons 127-138 aquaporin 4 Homo sapiens 67-71 27399338-9 2016 These effects are most likely due to the intermolecular van der Waals interactions between the butyl tails of each TBP molecule and the diluent hydrocarbon chain as all solvents in this study are relatively nonpolar. Hydrocarbons 144-155 TATA-box binding protein Homo sapiens 115-118 27117015-6 2016 The observed reduction in the RVOC/RNO2 ratio leads to a drastic decrease in local ozone production driven by the reduction in hydrocarbons. Hydrocarbons 127-139 NLR family pyrin domain containing 12 Homo sapiens 35-39 27410737-9 2016 These structural changes, caused by mismatch between the hydrophobic length of AQP4 and the bilayer hydrocarbon thickness, could explain the observed differences in water permeability with changes in bilayer thickness. Hydrocarbons 100-111 aquaporin 4 Homo sapiens 79-83 26854535-5 2016 We used our method to sample combinations of non-natural amino-acid substitutions that we introduced into Mcl-1 inhibitors in the context of a fixed helix-stabilizing hydrocarbon staple that increased peptide helical content and reduced proteolysis. Hydrocarbons 167-178 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 106-111 26919959-5 2016 Subsequent structure-activity studies suggested that the potency of BACs as Dhcr7 inhibitors decrease with the length of their hydrocarbon chain: C10 > C12 >> C14 > C16. Hydrocarbons 127-138 chromosome 12 open reading frame 57 Homo sapiens 146-149 27050321-2 2016 Ant genomes are marked by extreme rates of gene turnover, especially in gene families related to olfactory communication, such as the synthesis of cuticular hydrocarbons and the perception of environmental semiochemicals. Hydrocarbons 157-169 solute carrier family 25 member 6 Homo sapiens 0-3 27075823-6 2016 The ratio between the FTS and RWGS rates, which determines the C5+ hydrocarbons productivity, is strongly affected by the nature of the Fe-oxide matrix. Hydrocarbons 67-79 AKT interacting protein Homo sapiens 22-25 28970875-2 2016 In this manuscript we report on the use of a novel alpha-alkenylglycine derived amino acid to synthesise hydrocarbon constrained BH3-family sequences (BIM and BID). Hydrocarbons 105-116 BH3 interacting domain death agonist Homo sapiens 159-162 27130103-4 2016 Comparison of these results with those obtained using on-line pyrolysis coupled with GC-C-IRMS show that the thermal cracking of hydrocarbons occurs with a good isotopic fidelity between terminal and sub-terminal C-atom positions of the starting material and the related pyrolysis products (methane and ethylene). Hydrocarbons 129-141 guanylate cyclase 2C Homo sapiens 85-89 27130103-5 2016 On-line pyrolysis coupled with GC-C-IRMS can thus be used for tracing hydrocarbons biogeochemical processes. Hydrocarbons 70-82 guanylate cyclase 2C Homo sapiens 31-35 26774768-0 2016 Assessment of sediment hydrocarbon contamination from the 2009 Montara oil blow out in the Timor Sea. Hydrocarbons 23-34 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 97-100 27087591-6 2016 It is found that depending on the fractions of CH4 , C2 H6 , and CO2 , different sorbents allow for optimal H2 S removal and hydrocarbon recovery. Hydrocarbons 125-136 complement C2 Homo sapiens 53-68 26911867-11 2016 RESULTS: Sub-acute exposures of mice to hydrocarbon-rich ultrafine particles induced: (1) BALF neutrophil elevation; (2) lung mucosal inflammation, and (3) increased BALF IL-1beta concentration; with all three outcomes returning to baseline levels 10 days post-exposure. Hydrocarbons 40-51 interleukin 1 beta Mus musculus 171-179 26816269-7 2016 On the basis of mechanistic studies, we conclude that mononuclear nonheme high-spin iron(III)-acylperoxo complexes are strong oxidants capable of oxygenating hydrocarbons prior to their conversion into iron-oxo species via O-O bond cleavage. Hydrocarbons 158-170 spindlin 1 Homo sapiens 79-83 26928945-0 2016 Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Hydrocarbons 39-50 estrogen receptor 1 Homo sapiens 66-83 26451801-5 2016 The enhanced interfacial activity of JPs-MPD is explained in terms of chemical and hydration differences between the MPD and MEE ligands, where MPD has a shorter hydrocarbon chain and twice as many hydroxyl terminal groups as MEE. Hydrocarbons 162-173 mevalonate diphosphate decarboxylase Homo sapiens 41-44 26459451-2 2015 Here, we propose a new solution using a carbon-chain filling strategy to convert C10 terpene and lipids to jet fuel ranged hydrocarbons with aromatic hydrocarbon ingredients in the absence of hydrogen. Hydrocarbons 123-135 homeobox C10 Homo sapiens 81-84 27500678-8 2016 The application of mineral waters with the elevated content of hydrocarbons improves the clinical course of NAFLD with the concomitant esophagogastroduodenal pathology (p<0.001) and simultaneously reduces the severity of insulin resistance due to the lowering of the level of hyperinsulinemia (p<0.001). Hydrocarbons 63-75 insulin Homo sapiens 224-231 32355437-3 2016 These preliminary studies demonstrate the capability of INS to complement infrared spectroscopic characterisation of the hydrocarbon pool present in/on ZSM-5 during the MTG reaction. Hydrocarbons 121-132 serine protease 3 Homo sapiens 169-172 29896359-5 2016 In this work we show for the first time direct structural evidence of commensurate-to-incommensurate transition of linear hydrocarbon molecules (C2-C7) in a microporous MOF, by employing a number of analytical techniques including single crystal X-ray diffraction (SCXRD), in situ powder X-ray diffraction coupled with differential scanning calorimetry (PXRD-DSC), gas adsorption and molecular simulations. Hydrocarbons 122-133 desmocollin 3 Homo sapiens 359-362 26177489-6 2015 However, the resilience of certain microbial populations was observed, with a final increase in potential hydrocarbon-degrading populations as determined by both the alkB gene abundance and the predominance of well-known hydrocarbon-degrading phylotypes such as Rhodococcus, Ochrobactrum, Acinetobacter and Cupriavidus genera as determined by 16S rRNA-based DGGE fingerprinting. Hydrocarbons 106-117 alkB homolog 1, histone H2A dioxygenase Homo sapiens 166-170 26459451-2 2015 Here, we propose a new solution using a carbon-chain filling strategy to convert C10 terpene and lipids to jet fuel ranged hydrocarbons with aromatic hydrocarbon ingredients in the absence of hydrogen. Hydrocarbons 123-134 homeobox C10 Homo sapiens 81-84 26306982-4 2015 Furthermore, the introduction of an oxygen atom in the hydrocarbon scaffold of adamantane is deleterious to 11beta-HSD1 inhibition. Hydrocarbons 55-66 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 108-119 26599809-2 2015 This paper presents a portable-based mid-infrared attenuated total reflectance (MIR-ATR) sensor system that was used to quantify a number of environmentally relevant hydrocarbon contaminants in marine water. Hydrocarbons 166-177 membrane associated ring-CH-type finger 8 Homo sapiens 80-83 26346267-5 2015 The expression of two genes coding for alkane-1-monooxygenase enzymes was highly upregulated in the presence of hydrocarbon substrates. Hydrocarbons 112-123 alkane 1-monooxygenase Rhodococcus erythropolis PR4 39-61 26438854-4 2015 Here, we report that strains of the two most abundant marine cyanobacteria, Prochlorococcus and Synechococcus, produce and accumulate hydrocarbons, predominantly C15 and C17 alkanes, between 0.022 and 0.368% of dry cell weight. Hydrocarbons 134-146 placenta associated 8 Homo sapiens 162-165 26438854-4 2015 Here, we report that strains of the two most abundant marine cyanobacteria, Prochlorococcus and Synechococcus, produce and accumulate hydrocarbons, predominantly C15 and C17 alkanes, between 0.022 and 0.368% of dry cell weight. Hydrocarbons 134-146 cytokine like 1 Homo sapiens 170-173 25818947-7 2015 Along with previously-established anti-inflammatory, anti-viral, and hydrocarbon-solubilizing properties of mucin, the results of this study establish mucin as a readily-available, chemically-versatile, naturally-biocompatible alternative to complex multifunctional synthetic polymers as building blocks in the design of biomaterials for sustained drug delivery. Hydrocarbons 69-80 LOC100508689 Homo sapiens 108-113 26272099-3 2015 The binding affinity increases with the length of the ligands, indicating the importance of the van der Waals (vdW) interactions between the hydrocarbon tail and the hydrophobic calyx of BLG. Hydrocarbons 141-152 beta-lactoglobulin Bos taurus 187-190 26104145-0 2015 Polymorphisms in a desaturase 2 ortholog associate with cuticular hydrocarbon and male mating success variation in a natural population of Drosophila serrata. Hydrocarbons 66-77 Desaturase 2 Drosophila melanogaster 19-31 26035311-4 2015 The Anderson-Schulz-Flory chain-lengthening probabilities for products were up to 0.9 over Co-Pd nanocrystals, showing that long-chain hydrocarbons can be formed with high selectivity using the targeted design of Co-Pd nanocrystal catalysts. Hydrocarbons 135-147 COPD Homo sapiens 91-96 26035311-4 2015 The Anderson-Schulz-Flory chain-lengthening probabilities for products were up to 0.9 over Co-Pd nanocrystals, showing that long-chain hydrocarbons can be formed with high selectivity using the targeted design of Co-Pd nanocrystal catalysts. Hydrocarbons 135-147 COPD Homo sapiens 213-218 26324257-6 2015 Under environmental conditions a layer of water or hydrocarbon often forms between the probe tip and sample. Hydrocarbons 51-62 TOR signaling pathway regulator Homo sapiens 93-96 26413155-3 2015 We review general design strategies in ABPP, and highlight recent advances that are or could be pivotal to biofuels processes including applications of ABPP to cellulosic bioethanol, biodiesel, and phototrophic production of hydrocarbons. Hydrocarbons 225-237 amyloid beta precursor protein Homo sapiens 152-156 26189498-4 2015 We then synthesized stapled p53 mimetic analogues using pure hydrocarbon linkers and demonstrated their abilities to block the p53-MDM2 interaction and selectively kill p53 wild-type colorectal carcinoma HCT-116 cells but not p53 null cells. Hydrocarbons 61-72 tumor protein p53 Homo sapiens 28-31 26189498-4 2015 We then synthesized stapled p53 mimetic analogues using pure hydrocarbon linkers and demonstrated their abilities to block the p53-MDM2 interaction and selectively kill p53 wild-type colorectal carcinoma HCT-116 cells but not p53 null cells. Hydrocarbons 61-72 MDM2 proto-oncogene Homo sapiens 131-135 29449928-3 2015 Here, we report that fluorine, present in the form of a single fluoroalkyl amino acid side chain in the P1 position of the well-characterized serine-protease inhibitor BPTI, can fully restore inhibitor activity to a mutant that contains the corresponding hydrocarbon side chain at the same site. Hydrocarbons 255-266 spleen trypsin inhibitor I Bos taurus 168-172 25818947-7 2015 Along with previously-established anti-inflammatory, anti-viral, and hydrocarbon-solubilizing properties of mucin, the results of this study establish mucin as a readily-available, chemically-versatile, naturally-biocompatible alternative to complex multifunctional synthetic polymers as building blocks in the design of biomaterials for sustained drug delivery. Hydrocarbons 69-80 LOC100508689 Homo sapiens 151-156 25921752-1 2015 Six all-hydrocarbon-stapled Cdt1 MBD-derived peptides have been designed and synthesized to perturb the Cdt1-Mcm6 interaction, which is involved in DNA replication. Hydrocarbons 8-19 chromatin licensing and DNA replication factor 1 Homo sapiens 28-32 26172322-11 2015 Moreover, the highest binding energy to hydrocarbon chains were observed in the case of Ac-Phe-NMe2 (2). Hydrocarbons 40-51 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 95-99 25921752-1 2015 Six all-hydrocarbon-stapled Cdt1 MBD-derived peptides have been designed and synthesized to perturb the Cdt1-Mcm6 interaction, which is involved in DNA replication. Hydrocarbons 8-19 chromatin licensing and DNA replication factor 1 Homo sapiens 104-108 25921752-1 2015 Six all-hydrocarbon-stapled Cdt1 MBD-derived peptides have been designed and synthesized to perturb the Cdt1-Mcm6 interaction, which is involved in DNA replication. Hydrocarbons 8-19 minichromosome maintenance complex component 6 Homo sapiens 109-113 25077812-3 2015 CYP2C9 and CYP2E1 specifically metabolised sulfonylurea herbicides and halogenated hydrocarbons respectively. Hydrocarbons 83-95 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 0-6 26025169-7 2015 Canonical correspondence analysis revealed that soil moisture, nitrate, TOC, and pH had an important impact in shaping the microbial communities of the hydrocarbon-contaminated soil. Hydrocarbons 152-163 rhomboid 5 homolog 2 Homo sapiens 72-75 25404103-2 2015 They play important roles in insecticide metabolism and resistance, and growing numbers of P450 enzymes are now known to catalyse important physiological reactions, such as hormone metabolism or cuticular hydrocarbon synthesis. Hydrocarbons 205-216 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 91-95 25077812-3 2015 CYP2C9 and CYP2E1 specifically metabolised sulfonylurea herbicides and halogenated hydrocarbons respectively. Hydrocarbons 83-95 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 11-17 25746198-4 2015 Biotransformation of volatile and semivolatile hydrocarbons and oil compound groups was generally faster in the 10 mum than in the 30 mum dispersions, showing the importance of oil droplet size for biodegradation. Hydrocarbons 47-59 latexin Homo sapiens 115-118 25914113-2 2015 The neutral hydrocarbons and their radical cations were studied utilizing density functional theory (DFT) and ab initio (MP2) methods, which reproduce the experimental geometries and ionization potentials well. Hydrocarbons 12-24 tryptase pseudogene 1 Homo sapiens 121-124 25746198-4 2015 Biotransformation of volatile and semivolatile hydrocarbons and oil compound groups was generally faster in the 10 mum than in the 30 mum dispersions, showing the importance of oil droplet size for biodegradation. Hydrocarbons 47-59 latexin Homo sapiens 134-137 25704284-1 2015 Homocouplings of hydrocarbon groups including alkynyl (sp(1) ), alkyl (sp(3) ), and aryl (sp(2) ) have recently been investigated on surfaces with the interest of fabricating novel carbon nanostructures/nanomaterials and getting fundamental understanding. Hydrocarbons 17-28 Sp3 transcription factor Homo sapiens 71-76 25704284-1 2015 Homocouplings of hydrocarbon groups including alkynyl (sp(1) ), alkyl (sp(3) ), and aryl (sp(2) ) have recently been investigated on surfaces with the interest of fabricating novel carbon nanostructures/nanomaterials and getting fundamental understanding. Hydrocarbons 17-28 Sp2 transcription factor Homo sapiens 90-95 25727809-2 2015 This MOF exhibits reversible flexibility and breathing adsorption behaviors in response to light hydrocarbons, with high capacity. Hydrocarbons 97-109 lysine acetyltransferase 8 Homo sapiens 5-8 25769031-4 2015 Results indicate that the majority of observed reduced compounds corresponded to alicyclic hydrocarbons in the size range C10 to C17. Hydrocarbons 91-103 homeobox C10 Homo sapiens 122-125 25769031-4 2015 Results indicate that the majority of observed reduced compounds corresponded to alicyclic hydrocarbons in the size range C10 to C17. Hydrocarbons 91-103 cytokine like 1 Homo sapiens 129-132 25624485-0 2015 Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Hydrocarbons 39-50 KRAS proto-oncogene, GTPase Homo sapiens 31-35 25665932-4 2015 Further analysis, however, revealed apparent preference for the molecules with shorter hydrocarbon chain length for both PC and SPM in their relative incorporation into HDL by ABCA1 and ABCA7. Hydrocarbons 87-98 ATP binding cassette subfamily A member 1 Homo sapiens 176-181 25665932-4 2015 Further analysis, however, revealed apparent preference for the molecules with shorter hydrocarbon chain length for both PC and SPM in their relative incorporation into HDL by ABCA1 and ABCA7. Hydrocarbons 87-98 ATP binding cassette subfamily A member 7 Homo sapiens 186-191 25585967-0 2015 Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison. Hydrocarbons 100-112 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 53-81 25585967-8 2015 Overall, the findings from multiple techniques illustrate how drugs metabolizing CYP2B6 and CYP2A6 handle a common hydrocarbon found in the environment. Hydrocarbons 115-126 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 81-87 25585967-8 2015 Overall, the findings from multiple techniques illustrate how drugs metabolizing CYP2B6 and CYP2A6 handle a common hydrocarbon found in the environment. Hydrocarbons 115-126 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 92-98 25624485-0 2015 Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Hydrocarbons 39-50 SOS Ras/Rac guanine nucleotide exchange factor 1 Homo sapiens 59-63 25578273-1 2015 Carotenoids are mostly C40 terpenoids, a class of hydrocarbons that participate in various biological processes in plants, such as photosynthesis, photomorphogenesis, photoprotection, and development. Hydrocarbons 50-62 CCR4-NOT transcription complex subunit 11 Homo sapiens 23-26 25393936-5 2015 In particular, the CO2 /C3 H8 and CO2 /C3 H6 selectivities reached 10.5 and 42.7, respectively, for PVC-g-POEM/ZIF (40 %) MMMs; this indicates that it could be a promising membrane material for the purification of C3 hydrocarbons. Hydrocarbons 217-229 complement C2 Homo sapiens 24-37 25466921-2 2015 The AlkB-related alkane hydroxylases, which are integral membrane non-heme iron enzymes, play a key role in the microbial degradation of many of these hydrocarbons. Hydrocarbons 151-163 alkB homolog 1, histone H2A dioxygenase Homo sapiens 4-8 25424473-2 2015 The Bronsted acidity results in hydrocracking/isomerization of the heavier hydrocarbons formed on Co nanoparticles, while the mesoporosity contributes to suppressing the formation of lighter (C1-4 ) hydrocarbons. Hydrocarbons 199-211 heterogeneous nuclear ribonucleoprotein C Homo sapiens 192-196 26112900-8 2015 The experimental data show that the inactivation caused by peracids is dependent on hydrocarbon chain length of peracids with maximum inhibitory effect of medium-chain peracids (C8-C12 acyl chain), which correlates with calculated binding affinities to the CD45 active site. Hydrocarbons 84-95 protein tyrosine phosphatase receptor type C Homo sapiens 257-261 25484200-3 2015 Here we demonstrate that ACP70A is involved in the down-regulation of female sex pheromones and hydrocarbon (CHC) production. Hydrocarbons 96-107 Sex Peptide Drosophila melanogaster 25-31 25393512-0 2014 Structure-function mapping of key determinants for hydrocarbon biosynthesis by squalene and squalene synthase-like enzymes from the green alga Botryococcus braunii race B. Hydrocarbons 51-62 farnesyl-diphosphate farnesyltransferase 1 Homo sapiens 92-109 25423097-0 2014 Multifunctional anionic MOF material for dye enrichment and selective sorption of C2 hydrocarbons over methane via Ag(+)-exchange. Hydrocarbons 85-97 lysine acetyltransferase 8 Homo sapiens 24-27 25382814-2 2014 Both the structures and the outcomes of exploratory reactions of the parent hydrocarbon are predicted and explained in detail through high-level composite ab initio MO G4(MP2) computational studies. Hydrocarbons 76-87 tryptase pseudogene 1 Homo sapiens 171-174 25144541-1 2014 An infrared attenuated total reflection (IR-ATR) method for detecting, differentiating, and quantifying hydrocarbons dissolved in water relevant for oil spills by evaluating the "fingerprint" of the volatile organic compounds (VOCs) associated with individual oil types in the mid-infrared spectral range (i.e., 800-600 cm(-1)) is presented. Hydrocarbons 104-116 ATR serine/threonine kinase Homo sapiens 44-47 25316343-2 2014 The computational screening of reactions for different hydrocarbons (CH4, C2H6, C3H8, C2H4, and C2H2) as readily available carbon precursors for HCN formation, potential chemical transport agents, and for controlled carbon doping of deposited GaN was carried out with the B3LYP method in conjunction with basis sets up to aug-cc-pVTZ. Hydrocarbons 55-67 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 145-148 25381864-5 2014 Measuring HO2 formation from hydrocarbon oxidation is extremely important in determining the propensity of a fuel to follow chain-termination pathways from R + O2 compared to chain branching (leading to OH), helping to constrain and better validate detailed chemical kinetics models. Hydrocarbons 29-40 heme oxygenase 2 Homo sapiens 10-13 25247477-2 2014 AFM measurements of a partially fluorinated hydrocarbon molecule recorded with a CO-terminated tip are compared with state-of-the-art ab initio calculations. Hydrocarbons 44-55 TOR signaling pathway regulator Homo sapiens 95-98 25229208-0 2014 Secondary organic aerosol formation and organic nitrate yield from NO3 oxidation of biogenic hydrocarbons. Hydrocarbons 93-105 NBL1, DAN family BMP antagonist Homo sapiens 67-70 24892976-10 2014 To further validate this conclusion, we conjugated a short hydrocarbon onto the NTD to improve its cellular uptake, and found that the resulting conjugate, C16NTD, exhibited comparable intracellular accumulation as the q-NTD conjugate but superior anticancer activity due to its more effective release of free doxorubicin. Hydrocarbons 59-70 fuzzy planar cell polarity protein Homo sapiens 80-83 25207804-1 2014 The hydrocarbon-stapled peptide E1(S) allosterically inhibits the kinase activity of the epidermal growth factor receptor (EGFR) by blocking a distant but essential protein-protein interaction: a coiled coil formed from the juxtamembrane segment (JM) of each member of the dimeric partnership.1 Macrocyclization is not required for activity: the analogous unstapled (but alkene-bearing) peptide is equipotent in cell viability, immunoblot, and bipartite display experiments to detect coiled coil formation on the cell surface. Hydrocarbons 4-15 epidermal growth factor receptor Homo sapiens 89-121 25087744-4 2014 The SPB-OctylxDB-1 pair was predicted to provide the best separation of the siloxanes from the hydrocarbons. Hydrocarbons 95-107 surfactant protein B Homo sapiens 4-7 25087744-7 2014 The SPB-OctylxDB-1 stationary phase pair constrained the hydrocarbons to a narrow range of secondary retention times and fully isolated the siloxanes from the hydrocarbon band. Hydrocarbons 57-69 surfactant protein B Homo sapiens 4-7 25207804-1 2014 The hydrocarbon-stapled peptide E1(S) allosterically inhibits the kinase activity of the epidermal growth factor receptor (EGFR) by blocking a distant but essential protein-protein interaction: a coiled coil formed from the juxtamembrane segment (JM) of each member of the dimeric partnership.1 Macrocyclization is not required for activity: the analogous unstapled (but alkene-bearing) peptide is equipotent in cell viability, immunoblot, and bipartite display experiments to detect coiled coil formation on the cell surface. Hydrocarbons 4-15 epidermal growth factor receptor Homo sapiens 123-127 25087744-7 2014 The SPB-OctylxDB-1 stationary phase pair constrained the hydrocarbons to a narrow range of secondary retention times and fully isolated the siloxanes from the hydrocarbon band. Hydrocarbons 57-68 surfactant protein B Homo sapiens 4-7 25115702-8 2014 Additionally, as seen in other stapled peptide structures, the hydrocarbon staple itself contributes to binding through favourable interactions with Mdm2. Hydrocarbons 63-74 MDM2 proto-oncogene Homo sapiens 149-153 25218258-7 2014 Terminal Restriction Fragment Length Polymorphism (T-RFLP) analyses of alkB and 16S rRNA genes revealed that inhibition of hydrocarbon biodegradation was associated with a lack of change in microbial community composition. Hydrocarbons 123-134 alkB homolog 1, histone H2A dioxygenase Homo sapiens 71-75 24798952-1 2014 Peroxy (HO2 and RO2) radicals are important intermediates in tropospheric oxidation of hydrocarbons, and their accurate atmospheric measurements remain challenging. Hydrocarbons 87-99 heme oxygenase 2 Homo sapiens 8-11 24817343-3 2014 We also demonstrate a K24R mutation, necessary for cellular activity in hydrocarbon-stapled p53 peptides, is not required for analogous "double-click" peptides. Hydrocarbons 72-83 tumor protein p53 Homo sapiens 92-95 24715057-1 2014 Net reductive elimination (RE) of MeX (X = halide or pseudo-halide: Cl(-), CF3CO2(-), HSO4(-), OH(-)) is an important step during Pt-catalyzed hydrocarbon functionalization. Hydrocarbons 143-154 zinc finger SWIM-type containing 2 Homo sapiens 34-37 24418072-2 2014 In this study, the alpha-helical conformation and structural stability of single and double stapled all-hydrocarbon cross-linked p53 peptides when bound and unbound to MDM2 are investigated. Hydrocarbons 104-115 tumor protein p53 Homo sapiens 129-132 24892923-5 2014 This growing chemisorbed sulphur- or nitrogen-atom-initiated poly(CO2) chain further displaces physisorbed hydrocarbon, providing a continuous carbon dioxide selectivity. Hydrocarbons 107-118 complement C2 Homo sapiens 66-69 24918058-6 2014 Furthermore, beta2GPI converts the LPS bilayer aggregates into a stronger multilamellar form, and reduces the fluidity of the hydrocarbon moiety of LPS due to a rigidification of the acyl chains. Hydrocarbons 126-137 apolipoprotein H Homo sapiens 13-21 24771656-1 2014 The synthesis of Spi(tau-dec), derived from the selective alkylation of L-spinacine (4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid) at the tau-nitrogen of its heteroaromatic ring, with a linear hydrocarbon chain of 10 carbon atoms, is described here for the first time. Hydrocarbons 211-222 chromogranin A Homo sapiens 17-20 24675095-2 2014 Zebrafish (Danio rerio) possess two AHRR paralogs; AHRRa regulates constitutive AHR signaling during development, whereas AHRRb regulates polyaromatic hydrocarbon-induced gene expression. Hydrocarbons 151-162 aryl-hydrocarbon receptor repressor b Danio rerio 122-127 24613879-1 2014 Monoterpenes are naturally occurring plant hydrocarbons with multiple effects on the mevalonate pathway (MP), while statins competitively inhibit hydroxymethylglutarylcoenzyme-A reductase (HMGCR), the rate-limiting enzyme in the MP. Hydrocarbons 43-55 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 189-194 24806557-4 2014 RESULTS: Work shift exposure to total hydrocarbons was significantly associated with postshift urinary 1-naphthol (beta = 0.17; P = <0.0001), 2-naphthol (beta = 0.09; P = 0.005), and 2-hydroxyfluorene concentrations (beta = 0.08; P = 0.006), and a significant gene-environment interaction was observed with glutathione S-transferase mu-1. Hydrocarbons 38-50 glutathione S-transferase mu 1 Homo sapiens 310-340 24480410-4 2014 Association of Hsp70 with phosphatidylcholine (PC) liposomes is weak, with insertion of its Trps into the bilayer hydrocarbon region. Hydrocarbons 114-125 heat shock protein family A (Hsp70) member 4 Homo sapiens 15-20 24422448-3 2014 Peptides derived from the A Kinase Binding (AKB) domain of several AKAPs were chemically modified to contain an all-hydrocarbon staple and target the docking/dimerization domain of PKA-R, thereby occluding AKAP interactions. Hydrocarbons 116-127 A-kinase anchoring protein 1 Homo sapiens 67-71 24684470-1 2014 Recently 1-(phenylethynyl)naphthalene (1-PEN) was suggested to be the primary dimerization product of phenylpropargyl radicals and therefore an important polycyclic hydrocarbon in combustion processes. Hydrocarbons 165-176 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 41-44 24553295-5 2014 When hydrocarbon degrading potential was assessed, differences were observed in the extent of (14)C-benzene mineralisation under aerobic conditions with FTF 5 exhibiting the highest hydrocarbon removal potential compared to FTF 1 and 8. Hydrocarbons 5-16 nuclear receptor subfamily 5 group A member 2 Homo sapiens 153-156 24553295-5 2014 When hydrocarbon degrading potential was assessed, differences were observed in the extent of (14)C-benzene mineralisation under aerobic conditions with FTF 5 exhibiting the highest hydrocarbon removal potential compared to FTF 1 and 8. Hydrocarbons 182-193 nuclear receptor subfamily 5 group A member 2 Homo sapiens 153-156 24553295-6 2014 Further analysis indicated that the FTF 5 microbial community was substantially different from other FTF samples and dominated by putative hydrocarbon degraders belonging to Pseudomonads, Xanthomonads and Enterobacteria. Hydrocarbons 139-150 nuclear receptor subfamily 5 group A member 2 Homo sapiens 36-39 24553295-7 2014 However, hydrocarbon removal in FTF 5 under anaerobic conditions with nitrate and sulphate electron acceptors was limited suggesting that aerobic conditions were crucial for hydrocarbon removal. Hydrocarbons 9-20 nuclear receptor subfamily 5 group A member 2 Homo sapiens 32-35 24553295-7 2014 However, hydrocarbon removal in FTF 5 under anaerobic conditions with nitrate and sulphate electron acceptors was limited suggesting that aerobic conditions were crucial for hydrocarbon removal. Hydrocarbons 174-185 nuclear receptor subfamily 5 group A member 2 Homo sapiens 32-35 24646186-3 2014 Importantly, addition at C(1) was found to be barrierless via a van der Waals complex implying this mechanism can play a key role in forming methyl substituted PAHs in low temperature extreme environments such as the interstellar medium and hydrocarbon-rich atmospheres of planets and their moons in the outer Solar System. Hydrocarbons 241-252 heterogeneous nuclear ribonucleoprotein C Homo sapiens 25-29 24422448-6 2014 In summary, the novel hydrocarbon-stapled peptides developed in this study represent a new class of AKAP disruptors to study compartmentalized RII-regulated PKA signaling in cells. Hydrocarbons 22-33 A-kinase anchoring protein 1 Homo sapiens 100-104 24659987-0 2014 Effects of different compost amendments on the abundance and composition of alkB harboring bacterial communities in a soil under industrial use contaminated with hydrocarbons. Hydrocarbons 162-174 alkB homolog 1, histone H2A dioxygenase Homo sapiens 76-80 24494636-9 2014 The study suggests that DNP-SENS experiments can be carried on many types of uniform colloidal nanomaterials containing NMR-active nuclei, in the presence of either hydrophilic (ion-capped surfaces) or hydrophobic (capping ligands with long hydrocarbon chains) surface functionalities. Hydrocarbons 241-252 potassium channel tetramerization domain containing 1 Homo sapiens 28-32 24201004-3 2014 Thiol-labeled long chain hydrocarbon with bisphenol A (BPA) as head group was synthesized and self-assembled on the Au nanoparticle surface as the sensing probes, which showed a linear response upon the binding of estrogen receptor (ER-alpha) ranging from 1 to 30 nM. Hydrocarbons 25-36 estrogen receptor 1 Homo sapiens 214-231 24201004-3 2014 Thiol-labeled long chain hydrocarbon with bisphenol A (BPA) as head group was synthesized and self-assembled on the Au nanoparticle surface as the sensing probes, which showed a linear response upon the binding of estrogen receptor (ER-alpha) ranging from 1 to 30 nM. Hydrocarbons 25-36 estrogen receptor 1 Homo sapiens 233-241 24659987-11 2014 Our data indicates that compost amendments significantly change abundance and diversity pattern of alkB harboring microbes in Technosol and might be a useful agent to stimulate bioremediation of hydrocarbons in contaminated soils. Hydrocarbons 195-207 alkB homolog 1, histone H2A dioxygenase Homo sapiens 99-103 24277836-0 2013 Quantification of OH and HO2 radicals during the low-temperature oxidation of hydrocarbons by Fluorescence Assay by Gas Expansion technique. Hydrocarbons 78-90 heme oxygenase 2 Homo sapiens 25-28 24252369-9 2014 The proportion of liquid hydrocarbons is the highest when a montmorillonite K10 is acting as a catalyst. Hydrocarbons 25-37 keratin 10 Homo sapiens 76-79 24454560-3 2014 Also 8,8,11,11-tetrafluorononadecane (27) is prepared as a pure hydrocarbon containing a 1,4-di-CF2 motif. Hydrocarbons 64-75 ATPase H+ transporting accessory protein 1 Homo sapiens 96-99 25089051-3 2014 We also described interactions between chromatographed substances and various surfaces (silica-SiO2 and modified by hydrocarbon chains-RP-2, RP-8, RP-18 phases). Hydrocarbons 116-127 RP2 activator of ARL3 GTPase Homo sapiens 135-139 25462068-1 2014 Autoimmune reactions involving cytochrome P4502E1 (CYP2E1) are a feature of idiosyncratic liver injury induced by halogenated hydrocarbons and isoniazid, but are also detectable in about one third of the patients with advanced alcoholic liver disease (ALD) and chronic hepatitis C (CHC). Hydrocarbons 126-138 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 51-57 24376439-2 2013 Partial sequences for alkB, one of the structural genes of alkane hydroxylase, have been used to assess the composition of alkane-degrading communities, and to determine their responses to hydrocarbon inputs. Hydrocarbons 189-200 alkB homolog 1, histone H2A dioxygenase Homo sapiens 22-26 24376439-3 2013 We present here the first spatially extensive analysis of alkB in bacterioplankton of the northern Gulf of Mexico (nGoM), a region that experiences numerous hydrocarbon inputs. Hydrocarbons 157-168 alkB homolog 1, histone H2A dioxygenase Homo sapiens 58-62 24018188-0 2013 Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. Hydrocarbons 14-25 gonadotropin releasing hormone 1 Homo sapiens 72-102 24132303-0 2013 The binding nature of light hydrocarbons on Fe/MOF-74 for gas separation. Hydrocarbons 28-40 lysine acetyltransferase 8 Homo sapiens 47-50 24018188-1 2013 Three new DOTA-conjugated GnRH peptides with various hydrocarbon linkers were synthesized to evaluate the influences of the linkers on their receptor binding affinities. Hydrocarbons 53-64 gonadotropin releasing hormone 1 Homo sapiens 26-30 24018188-2 2013 The hydrocarbon linker displayed a profound impact on the receptor binding affinities of DOTA-conjugated GnRH peptides. Hydrocarbons 4-15 gonadotropin releasing hormone 1 Homo sapiens 105-109 23876507-5 2013 GC-MS analysis indicates that the final products include C11-C27 aliphatic hydrocarbons and aromatic hydrocarbons. Hydrocarbons 75-87 aldo-keto reductase family 1 member C4 Homo sapiens 57-60 23454918-4 2013 Although eubacterial communities (PCR-DGGE analysis) were similar for both soils, the alkB bacterial community was less diverse in S2 presumably due to impacts associated with elevated hydrocarbons. Hydrocarbons 185-197 alkB homolog 1, histone H2A dioxygenase Homo sapiens 86-90 23614645-0 2013 Formation of HCN+ in heterogeneous reactions of N2(+) and N+ with surface hydrocarbons. Hydrocarbons 74-86 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 13-16 23614645-1 2013 A significant increase of the ion yield at m/z 27 in collisions of low-energy ions of N2(+) and N(+) with hydrocarbon-covered room-temperature or heated surfaces of tungsten, carbon-fiber composite, and beryllium, not observed in analogous collisions of Ar(+), is ascribed to the formation of HCN(+) in heterogeneous reactions between N2(+) or N(+) and surface hydrocarbons. Hydrocarbons 106-117 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 293-296 24005767-1 2013 Alkenylglycine amino acids were assessed as potential candidates for hydrocarbon stapling and shown to be effective in stapling of the BID BH3 peptide. Hydrocarbons 69-80 BH3 interacting domain death agonist Homo sapiens 135-138 23961723-0 2013 NMR of short-chain hydrocarbons in nematic and smectic a liquid crystals. Hydrocarbons 19-31 survival of motor neuron 1, telomeric Homo sapiens 47-56 23946421-4 2013 A high resolution (1.7-A) X-ray crystal structure reveals its molecular interactions with the target protein MDMX, including multiple contacts with key amino acids as well as a role for the hydrocarbon staple itself in target engagement. Hydrocarbons 190-201 MDM4 regulator of p53 Homo sapiens 109-113 24011181-2 2013 In this work, deoxygenation of technical grade methyl oleate to diesel fuel aliphatic hydrocarbons (C15 - C18) is evaluated with several parameters including temperature, hydrogen pressure and reaction time in a stirred batch reactor over Pd/SBA-15 catalysts. Hydrocarbons 86-98 placenta associated 8 Homo sapiens 100-103 24011181-2 2013 In this work, deoxygenation of technical grade methyl oleate to diesel fuel aliphatic hydrocarbons (C15 - C18) is evaluated with several parameters including temperature, hydrogen pressure and reaction time in a stirred batch reactor over Pd/SBA-15 catalysts. Hydrocarbons 86-98 Bardet-Biedl syndrome 9 Homo sapiens 106-109 24011181-6 2013 Results show that H2 pressures greatly determine the total ester conversion and selectivity to C15 - C18 aliphatic hydrocarbons. Hydrocarbons 115-127 placenta associated 8 Homo sapiens 95-98 24011181-6 2013 Results show that H2 pressures greatly determine the total ester conversion and selectivity to C15 - C18 aliphatic hydrocarbons. Hydrocarbons 115-127 Bardet-Biedl syndrome 9 Homo sapiens 101-104 24011181-9 2013 CONCLUSIONS: Pd/SBA-15-necklacelike catalyst exhibits good catalytic performance with high selectivity to diesellike aliphatic hydrocarbons (C15 - C18). Hydrocarbons 127-139 placenta associated 8 Homo sapiens 141-144 24011181-9 2013 CONCLUSIONS: Pd/SBA-15-necklacelike catalyst exhibits good catalytic performance with high selectivity to diesellike aliphatic hydrocarbons (C15 - C18). Hydrocarbons 127-139 Bardet-Biedl syndrome 9 Homo sapiens 147-150 23701821-4 2013 Other peripheral proteins exhibit more complex bilayer contacts, for example classical protein kinase C isoforms (PKCs) bind as many as six lipids in stepwise fashion, resulting in the penetration of three PKC domains (C1A, C1B, C2) into the bilayer headgroup and hydrocarbon regions. Hydrocarbons 264-275 endogenous retrovirus group K member 1 Homo sapiens 219-227 23242513-5 2013 Respiration levels, as well as the abundance of alkB, encoding mono-oxygenases pivotal for hydrocarbon metabolism, were positively correlated with TPH degradation, demonstrating their usefulness as a proxy for hydrocarbon biodegradation. Hydrocarbons 91-102 alkB homolog 1, histone H2A dioxygenase Homo sapiens 48-52 23242513-5 2013 Respiration levels, as well as the abundance of alkB, encoding mono-oxygenases pivotal for hydrocarbon metabolism, were positively correlated with TPH degradation, demonstrating their usefulness as a proxy for hydrocarbon biodegradation. Hydrocarbons 210-221 alkB homolog 1, histone H2A dioxygenase Homo sapiens 48-52 23881641-1 2013 The formation of hydrocarbon pool (HCP) species during methanol-to-olefin (MTO) and ethanol-to-olefin (ETO) processes have been studied on individual micron-sized SAPO-34 crystals with a combination of in situ UV/Vis, confocal fluorescence, and synchrotron-based IR microspectroscopic techniques. Hydrocarbons 17-28 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 56-73 23881641-1 2013 The formation of hydrocarbon pool (HCP) species during methanol-to-olefin (MTO) and ethanol-to-olefin (ETO) processes have been studied on individual micron-sized SAPO-34 crystals with a combination of in situ UV/Vis, confocal fluorescence, and synchrotron-based IR microspectroscopic techniques. Hydrocarbons 17-28 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 103-106 24062826-0 2013 Bromination of hydrocarbons with CBr4, initiated by light-emitting diode irradiation. Hydrocarbons 15-27 carbonyl reductase 4 Homo sapiens 33-37 24062826-1 2013 The bromination of hydrocarbons with CBr4 as a bromine source, induced by light-emitting diode (LED) irradiation, has been developed. Hydrocarbons 19-31 carbonyl reductase 4 Homo sapiens 37-41 24062826-4 2013 The generation of CHBr3 was confirmed by NMR spectroscopy and GC-MS spectrometry analysis, indicating that the present bromination involves the homolytic cleavage of a C-Br bond in CBr4 followed by radical abstraction of a hydrogen atom from a hydrocarbon. Hydrocarbons 244-255 carbonyl reductase 4 Homo sapiens 181-185 23587061-7 2013 Small- and wide-angle X-ray scattering studies were conducted to correlate the degree of structural changes and hydrocarbon chain packing in SC lipids caused by these various classes of CPEs to the extent of permeation of interferon alpha-2b (IFNalpha), a 19 kDa protein drug, into human skin. Hydrocarbons 112-123 interferon alpha 2 Homo sapiens 222-241 23529398-3 2013 The extent of damage to organisms from PAH exposure is dependent on numerous factors including degree and type of PAH exposure, nature of the environment contaminated (i.e. terrestrial or aquatic), the ability of an organism to relocate to pristine environments, type and sensitivity of organism to specific hydrocarbon fractions and ability of the organism to metabolise different PAH fractions. Hydrocarbons 308-319 phenylalanine hydroxylase Homo sapiens 39-42 23687962-8 2013 Provided that the diffusion of the hydrocarbons close to the asphaltene nanoaggregates is three times smaller than the bulk diffusion, as the DOSY experiments show, this time of residence gives an average radius of exploration for the 2D hydrocarbon diffusion, r2D 3.9 nm, of the same order of magnitude as the aggregate sizes found by J. Eyssautier with SAXS and SANS in asphaltene solutions and by O. C. Mullins with the observation of gravitational gradients of asphaltenes in oilfield reservoirs. Hydrocarbons 35-47 USH1 protein network component sans Homo sapiens 366-370 23687962-8 2013 Provided that the diffusion of the hydrocarbons close to the asphaltene nanoaggregates is three times smaller than the bulk diffusion, as the DOSY experiments show, this time of residence gives an average radius of exploration for the 2D hydrocarbon diffusion, r2D 3.9 nm, of the same order of magnitude as the aggregate sizes found by J. Eyssautier with SAXS and SANS in asphaltene solutions and by O. C. Mullins with the observation of gravitational gradients of asphaltenes in oilfield reservoirs. Hydrocarbons 35-46 USH1 protein network component sans Homo sapiens 366-370 23675760-1 2013 Sorbent-enhanced steam methane reforming (SE-SMR) is an emerging technology for the production of high-purity hydrogen from hydrocarbons with in situ CO2 capture. Hydrocarbons 124-136 LY6/PLAUR domain containing 4 Homo sapiens 45-48 23537315-1 2013 A structurally unique class of hydrocarbon-soluble, ancillary-ligand-free, tetrametallic Co(I) and Ni(I) clusters is reported. Hydrocarbons 31-42 mitochondrially encoded cytochrome c oxidase I Homo sapiens 89-94 23617758-4 2013 More generally, our proposed mechanism for the reactivity of the gold/TiO2 interface should hold for oxidation of organic molecules with the structure of R-O-R", where R and R" are (saturated) hydrocarbons. Hydrocarbons 193-205 long intergenic non-protein coding RNA, regulator of reprogramming Homo sapiens 154-160 23643389-5 2013 Moreover, a hydrocarbon-stapled peptide that disrupts this interaction inhibits the growth of tumors expressing p110alpha E545K. Hydrocarbons 12-23 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens 112-121 23737238-3 2013 The basis for the ClogP(alk) model is the strong (R2 = 0.987) relationship between alkane/water partition coefficient and molecular surface area (MSA) that was observed for saturated hydrocarbons. Hydrocarbons 183-195 ALK receptor tyrosine kinase Homo sapiens 24-27 23737238-4 2013 The model treats a molecule as a perturbation of a saturated hydrocarbon molecule with the same MSA and uses increments defined for functional groups to quantify the extent to which logP(alk) is perturbed by the introduction each functional group. Hydrocarbons 61-72 ALK receptor tyrosine kinase Homo sapiens 187-190 24082506-1 2013 OBJECTIVES: In this study, we investigated whether cytochrome P450s (CYPs) induced by a typical chlorinated hydrocarbon insecticide chlordane (CLD) potentiate hepatic toxicity of carbon disulfide (CS2). Hydrocarbons 108-119 calsyntenin 2 Rattus norvegicus 197-200 23172551-2 2013 Modern ski waxes consist mainly of petroleum-derived straight-chain aliphatic hydrocarbons, perfluoro-n-alkanes or polyfluorinated n-alkanes. Hydrocarbons 78-90 SKI proto-oncogene Homo sapiens 7-10 23454909-3 2013 In long-term hydrocarbon-contaminated soil containing 10.3 g C10-C36 hydrocarbons kg(-1), 454 pyrosequencing detected the overrepresentation of potential hydrocarbon degrading genera such as Pseudomonas, Burkholderia, Mycobacterium and Gordonia whilst amplicons for PCR-DGGE were detected only with alkB primers targeting Pseudomonas. Hydrocarbons 13-24 homeobox C10 Homo sapiens 61-64 23454909-3 2013 In long-term hydrocarbon-contaminated soil containing 10.3 g C10-C36 hydrocarbons kg(-1), 454 pyrosequencing detected the overrepresentation of potential hydrocarbon degrading genera such as Pseudomonas, Burkholderia, Mycobacterium and Gordonia whilst amplicons for PCR-DGGE were detected only with alkB primers targeting Pseudomonas. Hydrocarbons 13-24 alkB homolog 1, histone H2A dioxygenase Homo sapiens 299-303 23454909-3 2013 In long-term hydrocarbon-contaminated soil containing 10.3 g C10-C36 hydrocarbons kg(-1), 454 pyrosequencing detected the overrepresentation of potential hydrocarbon degrading genera such as Pseudomonas, Burkholderia, Mycobacterium and Gordonia whilst amplicons for PCR-DGGE were detected only with alkB primers targeting Pseudomonas. Hydrocarbons 69-81 homeobox C10 Homo sapiens 61-64 23454909-3 2013 In long-term hydrocarbon-contaminated soil containing 10.3 g C10-C36 hydrocarbons kg(-1), 454 pyrosequencing detected the overrepresentation of potential hydrocarbon degrading genera such as Pseudomonas, Burkholderia, Mycobacterium and Gordonia whilst amplicons for PCR-DGGE were detected only with alkB primers targeting Pseudomonas. Hydrocarbons 69-80 homeobox C10 Homo sapiens 61-64 23256664-2 2013 By adjusting the CO(2)-to-steam ratio in the gas feed, the H(2)/CO ratio in the produced syn-gas could be easily adjusted in a single step to the desired value of 2 for methanol and hydrocarbon synthesis. Hydrocarbons 182-193 synemin Homo sapiens 89-92 23036853-3 2013 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a potent AhR ligand has not been shown to form any DNA adduct, but has a possibility to aggravate the toxicity of precarcinogenic polycyclic hydrocarbons through the induction of metabolic enzymes. Hydrocarbons 185-197 aryl hydrocarbon receptor Homo sapiens 53-56 23364630-1 2013 Terminal chronic renal failure patients show early insulin resistance (IR), characterised by alterations in the hydrocarbon metabolism and hyperinsulinaemia generally associated with dyslipidaemia and a proinflammatory condition. Hydrocarbons 112-123 insulin Homo sapiens 51-58 22885393-0 2012 Radon in groundwater contaminated by dissolved hydrocarbons in Santa Barbara d"Oeste, Sao Paulo State, Brazil. Hydrocarbons 47-59 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 86-89 23059874-11 2012 Although the GC-C-SER-IRMS method was developed for hydrocarbons, it can also be used for other organic gases and their mixtures. Hydrocarbons 52-64 guanylate cyclase 2C Homo sapiens 13-17 23071338-7 2012 Here we report the discovery of a hydrocarbon-stapled peptide that directly targets beta-catenin and interferes with its ability to serve as a transcriptional coactivator for T-cell factor (TCF) proteins, the downstream transcriptional regulators of the Wnt pathway. Hydrocarbons 34-45 catenin beta 1 Homo sapiens 84-96 23071338-7 2012 Here we report the discovery of a hydrocarbon-stapled peptide that directly targets beta-catenin and interferes with its ability to serve as a transcriptional coactivator for T-cell factor (TCF) proteins, the downstream transcriptional regulators of the Wnt pathway. Hydrocarbons 34-45 hepatocyte nuclear factor 4 alpha Homo sapiens 175-188 23071338-7 2012 Here we report the discovery of a hydrocarbon-stapled peptide that directly targets beta-catenin and interferes with its ability to serve as a transcriptional coactivator for T-cell factor (TCF) proteins, the downstream transcriptional regulators of the Wnt pathway. Hydrocarbons 34-45 hepatocyte nuclear factor 4 alpha Homo sapiens 190-193 23176753-0 2013 Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling. Hydrocarbons 48-59 galanin and GMAP prepropeptide Mus musculus 18-25 23176753-0 2013 Cyclic analogs of galanin and neuropeptide Y by hydrocarbon stapling. Hydrocarbons 48-59 neuropeptide Y Mus musculus 30-44 23071296-3 2013 The purpose of this work was to characterize the hydrocarbon-chain preference of PSS2 to gain insight on the specialized role of PSS2 in PS accumulation in the DHA-abundant tissues. Hydrocarbons 49-60 phosphatidylserine synthase 2 Homo sapiens 81-85 22562579-2 2012 Subsequent studies have established NcoA4 as a coactivator for a variety of nuclear receptors, including peroxisome proliferator activated receptors alpha and gamma, and receptors for steroid hormones, vitamins D and A, thyroid hormone, and aryl hydrocarbons. Hydrocarbons 246-258 nuclear receptor coactivator 4 Homo sapiens 36-41 23129539-5 2012 Although type II ligands typically block P450 activity, we report here that type II ligation can be harnessed to achieve just the opposite, that is, to favor biocatalysis and afford predictable oxidation of small hydrocarbon substrates with P450 2E1. Hydrocarbons 213-224 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 41-45 23129539-5 2012 Although type II ligands typically block P450 activity, we report here that type II ligation can be harnessed to achieve just the opposite, that is, to favor biocatalysis and afford predictable oxidation of small hydrocarbon substrates with P450 2E1. Hydrocarbons 213-224 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 241-245 22728982-3 2012 The aim of this study was to assess the potential of a previously bioremediated hydrocarbon contaminated soil (PBR) to increase TNT degradation rates. Hydrocarbons 80-91 translocator protein Homo sapiens 111-114 22728982-3 2012 The aim of this study was to assess the potential of a previously bioremediated hydrocarbon contaminated soil (PBR) to increase TNT degradation rates. Hydrocarbons 80-91 chromosome 16 open reading frame 82 Homo sapiens 128-131 26605579-1 2012 This work addresses the following paradox observed in diradicalar conjugated hydrocarbons: while the natural orbitals occupation numbers clearly indicate only two open-shell orbitals, i.e. two unpaired electrons, the minimal CAS zero-order description fails to reproduce accurately the electronic structures of the lowest states (spin density distribution and singlet-triplet energy gap, i.e., magnetic coupling). Hydrocarbons 77-89 BCAR1 scaffold protein, Cas family member Homo sapiens 225-228 22667323-0 2012 Dense coordination network capable of selective CO2 capture from C1 and C2 hydrocarbons. Hydrocarbons 75-87 heterogeneous nuclear ribonucleoprotein C Homo sapiens 65-74 22907772-8 2012 Over the 4 % Pt/ZrP catalyst, a 94 % carbon yield of diesel and 75 % carbon yield of C15 hydrocarbons (with 6-butylundecane as the major component) was achieved. Hydrocarbons 89-101 placenta associated 8 Homo sapiens 85-88 22871890-10 2012 At the XRE, endogenous genetic variation plus exogenous aryl hydrocarbon stimulation interact to control CTSL1 gene expression. Hydrocarbons 61-72 cathepsin L Homo sapiens 105-110 22579362-3 2012 We have assembled a HTGC-time of flight-MS (HTGC-ToF-MS) system from readily available products that is capable of rapid (<25 min) analysis of ~C10-100 hydrocarbon boiling equivalents and full mass spectral data recording up to m/z 1850. Hydrocarbons 155-166 homeobox C10 Homo sapiens 147-150 22511469-4 2012 The methanol-to-hydrocarbons (MTH) process is a key step in such routes, and can be tuned into production of gasoline-rich (methanol to gasoline; MTG) or olefin-rich (methanol to olefins; MTO) product mixtures by proper choice of catalyst and reaction conditions. Hydrocarbons 16-28 serine protease 3 Homo sapiens 146-149 22999885-5 2012 We previously discovered that a hydrocarbon-stapled MCL-1 BH3 helix is an exquisitely selective MCL-1 antagonist. Hydrocarbons 32-43 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 52-57 22999885-5 2012 We previously discovered that a hydrocarbon-stapled MCL-1 BH3 helix is an exquisitely selective MCL-1 antagonist. Hydrocarbons 32-43 MCL1 apoptosis regulator, BCL2 family member Homo sapiens 96-101 22927409-4 2012 Oenocyte-directed RNAi knock-down of Drosophila CYP4G1 or NADPH-cytochrome P450 reductase results in flies deficient in cuticular hydrocarbons, highly susceptible to desiccation, and with reduced viability upon adult emergence. Hydrocarbons 130-142 Cytochrome P450-4g1 Drosophila melanogaster 48-54 22927409-4 2012 Oenocyte-directed RNAi knock-down of Drosophila CYP4G1 or NADPH-cytochrome P450 reductase results in flies deficient in cuticular hydrocarbons, highly susceptible to desiccation, and with reduced viability upon adult emergence. Hydrocarbons 130-142 Cytochrome P450 reductase Drosophila melanogaster 58-89 22564968-3 2012 The main finding of these studies is that mucin binding to wax disordered slightly the conformation of the hydrocarbon chains of wax and caused the wax carbonyls to become hydrogen bonded or experience a more hydrophilic environment. Hydrocarbons 107-118 LOC100508689 Homo sapiens 42-47 22311706-1 2012 The aryl hydrocarbon receptor (AhR), a ligand-activated member of the basic helix-loop-helix (bHLH)/PER-ARNT-SIM (PAS) transcription superfamily, is known to regulate the toxicity of polyaromatic halogenated hydrocarbon environmental chemicals, most notably dioxin. Hydrocarbons 9-20 aryl hydrocarbon receptor Homo sapiens 31-34 22622039-5 2012 A hydrocarbon-stapled peptide modeled after the BIM BH3 helix broadly targeted BCL-2 family proteins with high affinity, blocked inhibitory antiapoptotic interactions, directly triggered proapoptotic activity, and induced dose-responsive and BH3 sequence-specific cell death of hematologic cancer cells. Hydrocarbons 2-13 BCL2 apoptosis regulator Homo sapiens 79-84 22302156-8 2012 Analyses of long-chain hydrocarbon compounds with different functional groups revealed that long-chain aliphatic aldehydes elicited an activation of defined OR37 glomeruli, each of them responding preferentially to an aldehyde with different chain lengths. Hydrocarbons 23-34 olfactory receptor family 5 subfamily H member 8 (gene/pseudogene) Homo sapiens 157-161 22530552-0 2012 Takovite-aluminosilicate-Cr materials prepared by adsorption of Cr3+ from industrial effluents as catalysts for hydrocarbon oxidation reactions. Hydrocarbons 112-123 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 64-67 22466954-7 2012 Microbial adhesion to hydrocarbon test showed that cell surface of MT5 was less hydrophobic and its cell length became significantly longer in the presence of 1-butanol, as observed by scanning electron microscopy. Hydrocarbons 22-33 protease, serine 32 Mus musculus 67-70 26596756-5 2012 Following the framework of the OPLS-AA parametrization, we refined the torsional parameters for hydrocarbons by fitting to the gas-phase ab initio energy profiles calculated at the accurate MP2/aug-cc-pVTZ theory level. Hydrocarbons 96-108 tryptase pseudogene 1 Homo sapiens 190-193 22189140-3 2012 Isothermal calorimetric characterization of the role of hydrocarbon substitution of this six-membered ring, upon binding the HCV NS3 protease, was found to be exclusively entropic in nature. Hydrocarbons 56-67 KRAS proto-oncogene, GTPase Homo sapiens 129-132 22285943-5 2012 These results suggest that the hydrophobic carborane cage may interact more efficiently than the hydrocarbons with the hydrophobic surface of VDR. Hydrocarbons 97-109 vitamin D receptor Homo sapiens 142-145 22092501-2 2012 Polymorphisms at N-acetyltransferase 2 locus, coding for an enzyme catalyzing acetylation of aromatic amines, might cause DNA adduct formation because of improper acetylation of these polyaromatic hydrocarbons. Hydrocarbons 197-209 N-acetyltransferase 2 Homo sapiens 17-38 22119305-4 2012 The C10-C40 hydrocarbons were destroyed, desorbed or co-evaporated with moisture from soil by microwave heating. Hydrocarbons 12-24 homeobox C10 Homo sapiens 4-7 22119305-4 2012 The C10-C40 hydrocarbons were destroyed, desorbed or co-evaporated with moisture from soil by microwave heating. Hydrocarbons 12-24 CCR4-NOT transcription complex subunit 11 Homo sapiens 8-11 22378219-0 2012 Hydrocarbons and kidney damage: potential use of neutrophil gelatinase-associated lipocalin and sister chromatide exchange. Hydrocarbons 0-12 lipocalin 2 Homo sapiens 49-91 22321244-0 2012 Sulphur stable isotope systematics in diagenetic pyrite from the North Sea hydrocarbon reservoirs revealed by laser combustion analysis. Hydrocarbons 75-86 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 71-74 21821260-6 2011 The gamma(C) values of the studied polymeric solids were found to be different for the mixtures composed of hydrocarbon surfactants in comparison with those of hydrocarbon and fluorocarbon surfactants. Hydrocarbons 108-119 interleukin 2 receptor subunit gamma Homo sapiens 4-12 21803694-0 2011 A mutant Ahr allele protects the embryonic kidney from hydrocarbon-induced deficits in fetal programming. Hydrocarbons 55-66 aryl-hydrocarbon receptor Mus musculus 9-12 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 WT1 transcription factor Mus musculus 97-100 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 WT1 transcription factor Mus musculus 154-157 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 syndecan 1 Mus musculus 182-192 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 syndecan 1 Mus musculus 194-198 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 paired box 2 Mus musculus 200-217 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 paired box 2 Mus musculus 219-223 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 epidermal growth factor receptor Mus musculus 226-258 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 epidermal growth factor receptor Mus musculus 260-264 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 retinoic acid receptor, alpha Mus musculus 271-300 21803694-5 2011 RESULTS: Hydrocarbon challenge of metanephri from C57 mice altered Wilms" tumor suppressor gene (Wt1) mRNA splice variant ratios and reduced mRNAs of the Wt1 transcriptional targets syndecan-1 (Sdc1) paired box gene 2 (Pax2), epidermal growth factor receptor (Egfr), and retinoic acid receptor, alpha (Raralpha). Hydrocarbons 9-20 retinoic acid receptor, alpha Mus musculus 302-310 21803694-7 2011 In contrast, metanephri from D2N mice were spared hydrocarbon-induced changes in Wt1 splice variant ratios and deficits of differentiation. Hydrocarbons 50-61 WT1 transcription factor Mus musculus 81-84 21889950-4 2011 Transcription factor binding site analysis revealed an over-representation of aryl hydrocarbon response elements (AHREs) in AHR-bound regions with 53% (2 h) and 68% (24 h) of them containing at least one AHRE. Hydrocarbons 83-94 aryl-hydrocarbon receptor Mus musculus 114-117 22536539-4 2012 The cuticular hydrocarbon transfer experiment indicated that cuticular hydrocarbons of TW1 females have an inhibitory effect on courtship by Mel6 males. Hydrocarbons 14-25 gamma-Tubulin at 37C Drosophila melanogaster 87-90 22536539-4 2012 The cuticular hydrocarbon transfer experiment indicated that cuticular hydrocarbons of TW1 females have an inhibitory effect on courtship by Mel6 males. Hydrocarbons 14-25 fs(2)mel6 Drosophila melanogaster 141-145 22536539-4 2012 The cuticular hydrocarbon transfer experiment indicated that cuticular hydrocarbons of TW1 females have an inhibitory effect on courtship by Mel6 males. Hydrocarbons 71-83 gamma-Tubulin at 37C Drosophila melanogaster 87-90 22536539-4 2012 The cuticular hydrocarbon transfer experiment indicated that cuticular hydrocarbons of TW1 females have an inhibitory effect on courtship by Mel6 males. Hydrocarbons 71-83 fs(2)mel6 Drosophila melanogaster 141-145 23227150-2 2012 We have previously shown that aging and insulin signaling significantly influence the composition and sexual attractiveness of Drosophila melanogaster female cuticular hydrocarbons (CHCs), some of which are known to be sex pheromones. Hydrocarbons 168-180 Insulin-like receptor Drosophila melanogaster 40-47 22034842-1 2011 In the present work, the factors that determine EPR line shapes from spin labels at the protein-hydrocarbon interface of a beta-barrel membrane protein are examined. Hydrocarbons 96-107 amyloid beta precursor protein Homo sapiens 121-127 21862192-0 2011 Vertical fluxes of aromatic and aliphatic hydrocarbons in the Northwestern Mediterranean Sea. Hydrocarbons 42-54 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 89-92 21821260-6 2011 The gamma(C) values of the studied polymeric solids were found to be different for the mixtures composed of hydrocarbon surfactants in comparison with those of hydrocarbon and fluorocarbon surfactants. Hydrocarbons 160-171 interleukin 2 receptor subunit gamma Homo sapiens 4-12 21675760-7 2011 The perfluoro fatty acid vesicle solutions display a much higher yield stress and viscoelastic properties, which depend on two factors: (i) the fluorinated alkyl chains of PFL(-), which are in the crystalline state at room temperature because of their rigid chains compared to analogous hydrocarbon chains, and (ii) the packing of the vesicles, which is very dense. Hydrocarbons 287-298 profilin 2 Homo sapiens 172-175 21715162-4 2011 In addition, it preferentially degraded short-chain hydrocarbons (<=C25) in the early cultivation phase and accumulated hydrocarbons with chain-lengths from C23 to C27 during later cultivation stage with crude oil as the sole carbon source. Hydrocarbons 123-135 nucleolin Homo sapiens 160-163 21567188-10 2011 Phylogenetic analysis of alkB denoted a shift of the hydrocarbon-degrading bacterial community from Gram-positive bacteria in the control zone (most similar to Mycobacterium and Nocardia types) to Gram-negative genotypes in the contaminated zones (Acinetobacter and alkB sequences with little similarity to those of known bacteria). Hydrocarbons 53-64 alkB homolog 1, histone H2A dioxygenase Homo sapiens 25-29 21567188-10 2011 Phylogenetic analysis of alkB denoted a shift of the hydrocarbon-degrading bacterial community from Gram-positive bacteria in the control zone (most similar to Mycobacterium and Nocardia types) to Gram-negative genotypes in the contaminated zones (Acinetobacter and alkB sequences with little similarity to those of known bacteria). Hydrocarbons 53-64 alkB homolog 1, histone H2A dioxygenase Homo sapiens 266-270 21862343-4 2011 It has been demonstrated that FXR regulates the metabolism of not just bile acids, but also of fats and hydrocarbon metabolites. Hydrocarbons 104-115 nuclear receptor subfamily 1 group H member 4 Homo sapiens 30-33 21879948-5 2011 Whatever the site, the finest PM (UF and F) induced the mRNA expression of CYP1A1, a biomarker of polyaromatic hydrocarbons (PAH) exposure, NQO-1 and heme HO-1, two antioxidant responsive element-driven genes; and two effect biomarkers, GM-CSF, a proinflammatory cytokine and amphiregulin (AR), a growth factor. Hydrocarbons 111-123 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 75-81 21672528-0 2011 Helix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter. Hydrocarbons 47-58 ATP binding cassette subfamily A member 1 Homo sapiens 104-109 21296101-1 2011 The US Air Force wrote the specification for the first official hydrocarbon-based jet fuel, JP-4, in 1951. Hydrocarbons 64-75 junctophilin 4 Rattus norvegicus 92-96 21296101-7 2011 Subchronic studies for 90 days with JP-8 and JP-4 showed little toxicity with the primary effect being male rat specific hydrocarbon nephropathy. Hydrocarbons 121-132 junctophilin 4 Rattus norvegicus 45-49 21672528-7 2011 In summary, hydrocarbon stapling of amphipathic peptides increases their helicity, makes them resistant to proteolysis and enhances their ability to promote cholesterol efflux by the ABCA1 transporter, indicating that this peptide modification may be useful in the development of apolipoprotein mimetic peptides. Hydrocarbons 12-23 ATP binding cassette subfamily A member 1 Homo sapiens 183-188 21612250-7 2011 The covalently attached hydrocarbon chain molecules increased the hydrophobicity of AMH-3 and MCM-22 layer surfaces and therefore allow the possibility of effectively dispersing these materials in polymer matrices for thin film/membrane applications. Hydrocarbons 24-35 anti-Mullerian hormone Homo sapiens 84-87 21644510-2 2011 Our previous studies revealed that certain hydrocarbons (short-chain n-alkanes [C(6)-C(10)] and monoaromatics [toluene, o-xylene, m-xylene]) in residual naphtha entrained in the tailings are biodegraded to CH(4) by a consortium of microorganisms. Hydrocarbons 43-55 homeobox C10 Homo sapiens 85-90 21516101-6 2011 Furthermore, the increased courtship caused by depletion of male cuticular hydrocarbons was suppressed by a mutation in the olfactory receptor Or47b. Hydrocarbons 75-87 Odorant receptor 47b Drosophila melanogaster 143-148 21413709-5 2011 It was found that both the gamma(cac) and the CAC were lower than those for reported traditional hydrocarbon surfactants. Hydrocarbons 97-108 carbonic anhydrase 2 Homo sapiens 27-37 21500305-1 2011 The gas-phase ion chemistry of GeF(4) and of its mixtures with water, ammonia and hydrocarbons was investigated by ion trap mass spectrometry (ITMS) and ab initio calculations. Hydrocarbons 82-94 Rho guanine nucleotide exchange factor 4 Homo sapiens 31-37 21442718-7 2011 Upon interaction with recoverin, the hydrophobic hydrocarbon chains become less ordered. Hydrocarbons 49-60 recoverin Homo sapiens 22-31 21442718-13 2011 MAG causes small ordering in the hydrocarbon chains region and an increase in the hydration of the polar head groups. Hydrocarbons 33-44 myelin associated glycoprotein Homo sapiens 0-3 21452804-5 2011 We have studied the influence of hydrophobicity on the surface-catalyzed assembly of IAPP on ultrasmooth hydrocarbon films grown on ion-beam-modified mica surfaces by atomic force microscopy. Hydrocarbons 105-116 islet amyloid polypeptide Homo sapiens 85-89 21327210-9 2011 PAH and AH fingerprint ratios, such as pristane to phytane (Pr/Ph), phenanthrene to anthracene (Phe/An) and fluoranthene to pyrene (Fl/Py), suggest that hydrocarbons in all harbours may originate from both pyrolytic and petrogenic sources derived from discharge of untreated sewage and wastewater or from direct input by ship traffic in the area. Hydrocarbons 153-165 inositol polyphosphate-5-phosphatase D Homo sapiens 321-325 21329368-7 2011 Alternatively, the overlapping helix 10 C-terminal domains of apoA-I were observed to be extremely mobile or "promiscuous", transiently exposing limited hydrocarbon regions of PL. Hydrocarbons 153-164 apolipoprotein A1 Homo sapiens 62-68 21349728-0 2011 Parallel solid-phase synthesis of a small library of linear and hydrocarbon-bridged analogues of VEGF(81-91): potential biological tools for studying the VEGF/VEGFR-1 interaction. Hydrocarbons 64-75 vascular endothelial growth factor A Homo sapiens 97-101 21634191-4 2011 Furthermore, the column chromatography and GC-MS analysis revealed that content of lightly components including saturated and aromatic hydrocarbons exceeded 40%, specifically was alkenes (> C15), hydrocarbon derivatives, and a small amount aromatic hydrocarbons. Hydrocarbons 135-146 placenta associated 8 Homo sapiens 193-196 21634191-4 2011 Furthermore, the column chromatography and GC-MS analysis revealed that content of lightly components including saturated and aromatic hydrocarbons exceeded 40%, specifically was alkenes (> C15), hydrocarbon derivatives, and a small amount aromatic hydrocarbons. Hydrocarbons 135-147 placenta associated 8 Homo sapiens 193-196 21416750-5 2011 Some of these high ozone parcels and plumes have been linked to a combination of unique wind conditions and episodic hydrocarbon emission events from the Houston Ship Channel. Hydrocarbons 117-128 inositol polyphosphate-5-phosphatase D Homo sapiens 162-166 21282161-8 2011 Thereafter, declining hydrocarbon pollution was followed by the onset (1950s), peak (1965-1977) and decline (post-1980s) in total PCB concentrations. Hydrocarbons 22-33 pyruvate carboxylase Homo sapiens 130-133 21191074-8 2011 Taken together, our findings uncover an IL-1alpha-dependent mechanism of neutrophil recruitment in hydrocarbon-induced peritonitis and illustrate the interactions of innate immune pathways in chronic inflammation. Hydrocarbons 99-110 interleukin 1 alpha Homo sapiens 40-49 20961099-5 2010 At high protein/lipid ratios, rapid (1)H spin diffusion from the lipid chains to the protein was observed, indicating that HNP-1 was well inserted into the hydrocarbon core of the bilayer. Hydrocarbons 156-167 HNP1 Homo sapiens 123-128 21085725-2 2011 The reaction produces C(2)+ hydrocarbons and hydrogen in a single step at 1 atm in a continuous flow reactor at a nominal residence time of 60 s. The essentially complete conversion of methane appears to be due to protolytic activation of methane in the presence of H(+)AlBr(4)(-). Hydrocarbons 28-40 ATM serine/threonine kinase Homo sapiens 76-79 21183436-9 2010 It binds to dioxin, translocates to nucleus and together with hydrocarbon nuclear translocator (ARNT) and xenobiotic responsive element (XRE) increases the expression of CYP1A1.Dioxins are classified as known human carcinogens, but they also cause noncancerous effects like atherosclerosis, hypertension, and diabetes. Hydrocarbons 62-73 aryl hydrocarbon receptor nuclear translocator Homo sapiens 96-100 21183436-9 2010 It binds to dioxin, translocates to nucleus and together with hydrocarbon nuclear translocator (ARNT) and xenobiotic responsive element (XRE) increases the expression of CYP1A1.Dioxins are classified as known human carcinogens, but they also cause noncancerous effects like atherosclerosis, hypertension, and diabetes. Hydrocarbons 62-73 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 170-176 21088491-1 2010 Atomistic simulations of a set of stapled peptides derived from the transactivation domain of p53 (designed by Verdine & colleagues, JACS 2007 129:2456) and complexed to MDM2 reveal that the good binders are uniquely characterized by higher helicity and by extensive interactions between the hydrocarbon staples and the MDM2 surface; in contrast the poor binders have reduced helicity and their staples are mostly solvent exposed. Hydrocarbons 296-307 tumor protein p53 Homo sapiens 94-97 21088491-1 2010 Atomistic simulations of a set of stapled peptides derived from the transactivation domain of p53 (designed by Verdine & colleagues, JACS 2007 129:2456) and complexed to MDM2 reveal that the good binders are uniquely characterized by higher helicity and by extensive interactions between the hydrocarbon staples and the MDM2 surface; in contrast the poor binders have reduced helicity and their staples are mostly solvent exposed. Hydrocarbons 296-307 MDM2 proto-oncogene Homo sapiens 174-178 21088491-1 2010 Atomistic simulations of a set of stapled peptides derived from the transactivation domain of p53 (designed by Verdine & colleagues, JACS 2007 129:2456) and complexed to MDM2 reveal that the good binders are uniquely characterized by higher helicity and by extensive interactions between the hydrocarbon staples and the MDM2 surface; in contrast the poor binders have reduced helicity and their staples are mostly solvent exposed. Hydrocarbons 296-307 MDM2 proto-oncogene Homo sapiens 324-328 20812720-3 2010 The observed selectivity of UK101 for the LMP2 subunit is rationalized by the requirement for both a linear hydrocarbon chain at the N terminus and a bulky group at the C terminus of the inhibitor, because the LMP2 subunit has a much more favorable hydrophobic pocket interacting with the linear hydrocarbon chain, and the bulky group at the C terminus has a steric clash with the Tyr 169 in beta5 subunit. Hydrocarbons 296-307 proteasome 20S subunit beta 9 Homo sapiens 42-46 20853818-4 2010 To explore the limits of hydrocarbon ruler acyl chain selectivity, we have modified the single Gly88Cys sulfhydryl group with linear alkyl units and identified C10 as the shortest acyl chain to be efficiently utilized. Hydrocarbons 25-36 chromosome 12 open reading frame 57 Homo sapiens 160-163 20673676-4 2010 At depths of several kilometers below the sea surface, the occurrence and spread of the deep sea oil spill could be evaluated better by quantifying and characterizing the dissolved hydrocarbon signature, rather than just the investigation of hydrocarbons in the suspended particulate matter. Hydrocarbons 181-192 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 93-96 20812720-3 2010 The observed selectivity of UK101 for the LMP2 subunit is rationalized by the requirement for both a linear hydrocarbon chain at the N terminus and a bulky group at the C terminus of the inhibitor, because the LMP2 subunit has a much more favorable hydrophobic pocket interacting with the linear hydrocarbon chain, and the bulky group at the C terminus has a steric clash with the Tyr 169 in beta5 subunit. Hydrocarbons 108-119 proteasome 20S subunit beta 9 Homo sapiens 42-46 20411239-1 2010 In August of 2005 a study was carried out to evaluate contamination of aliphatic hydrocarbons(AHc) in water, suspended particulate matter (SPM) and sediments from Daliao River system composed of the Hun River, Taizi River, and Daliao River in a heavy industrial area of northeast of China. Hydrocarbons 81-93 nuclear receptor subfamily 0 group B member 1 Homo sapiens 94-97 20734861-2 2010 The FRO-AOD system has been ascertained to be considerably changed in the plasma, tear, and urine of persons contacting a mixture of petrol and Grade BP-1 solvent with organic solvents and aromatic hydrocarbons and a mixture of 1,2-dichloroethane with chlorinated hydrocarbons under industrial conditions. Hydrocarbons 264-276 BP1 Homo sapiens 150-154 20572170-1 2010 High-spin organic structures can be obtained from fused polycyclic hydrocarbons, by converting selected peripheral HC(sp(2)) sites into H(2)C(sp(3)) ones, guided by Ovchinnikov"s rule. Hydrocarbons 67-79 spindlin 1 Homo sapiens 5-9 19944423-4 2010 Gamma(max) decreases and Amin increases with an increase of the hydrocarbon chain length of FC8-HCn. Hydrocarbons 64-75 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 96-99 20148214-4 2010 Both are air sensitive, hydrocarbon soluble species that gave the corresponding molecular ions in their mass spectra (MALDI-TOF). Hydrocarbons 24-35 FEZ family zinc finger 2 Homo sapiens 124-127 19944423-5 2010 Steady-state fluorescence and NMR measurements demonstrated that both fluorocarbon and hydrocarbon chains of FC8-HCn molecules were incorporated inside the aggregates. Hydrocarbons 87-98 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 113-116 19944423-8 2010 Moreover, the absolute values of DeltaG(0)(agg) and DeltaH(0)(agg) increase with an increase of the hydrocarbon chain length of FC8-HCn at 298 K. Hydrocarbons 100-111 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 132-135 20831950-3 2010 Indeed, mutations in the CheB42a gene specifically alter male response to female-specific cuticular hydrocarbons. Hydrocarbons 100-112 Chemosensory protein B 42a Drosophila melanogaster 25-32 20930378-6 2010 The present observations suggest the need to reveal the mechanism by which CYP1A1 expression is modified by flavonoids for risk assessment, since CYP1A1 activates environmental carcinogenic polycyclic hydrocarbons and flavonoids are major constituents in food. Hydrocarbons 201-213 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 75-81 20930378-6 2010 The present observations suggest the need to reveal the mechanism by which CYP1A1 expression is modified by flavonoids for risk assessment, since CYP1A1 activates environmental carcinogenic polycyclic hydrocarbons and flavonoids are major constituents in food. Hydrocarbons 201-213 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 146-152 19824022-0 2010 Aryl hydrocarbon nuclear translocator (hypoxia inducible factor 1beta) activity is required more during early than late tumor growth. Hydrocarbons 5-16 aryl hydrocarbon receptor nuclear translocator Mus musculus 39-69 20831950-5 2010 As GM2-AP binds specifically to the GM2 ganglioside, we have proposed that CheB42a and other CheBs function by interacting directly with the lipid-like cuticular hydrocarbons of Drosophila melanogaster and modulating their detection by transmembrane receptors. Hydrocarbons 162-174 ganglioside GM2 activator Homo sapiens 3-9 20831950-5 2010 As GM2-AP binds specifically to the GM2 ganglioside, we have proposed that CheB42a and other CheBs function by interacting directly with the lipid-like cuticular hydrocarbons of Drosophila melanogaster and modulating their detection by transmembrane receptors. Hydrocarbons 162-174 Chemosensory protein B 42a Drosophila melanogaster 75-82 19877632-5 2009 This discovery could open a new route to hydrocarbons via i-propanol from syn-gas or biobased feedstocks. Hydrocarbons 41-53 synemin Homo sapiens 74-77 19820158-1 2009 Hydrocarbon seeps provide inputs of petroleum hydrocarbons to widespread areas of the Timor Sea. Hydrocarbons 0-11 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 92-95 19820158-9 2009 Interestingly, however, copy numbers of alkB genes increased substantially in sediments exposed directly to active seepage even though only low or undetectable concentrations of hydrocarbons were measured in these sediments in complementary geochemical analyses due to efficient biodegradation. Hydrocarbons 178-190 alkB homolog 1, histone H2A dioxygenase Homo sapiens 40-44 19615983-3 2009 Our interest in pituitary-dependent regulation of AHR levels was prompted by two findings from our laboratory: (1) hypophysectomized rats have reduced hepatic levels of AHR protein; and (2) glucocorticoids increase AHR expression and aromatic hydrocarbon responsiveness in rodent hepatoma cells. Hydrocarbons 243-254 aryl hydrocarbon receptor Rattus norvegicus 50-53