PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
27612203-0	2016	The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.	fluorocyclopentenylcytosine	20-47	uridine-cytidine kinase 2	Homo sapiens	74-99
27612203-0	2016	The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.	fluorocyclopentenylcytosine	49-56	uridine-cytidine kinase 2	Homo sapiens	74-99
32295203-0	2020	RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.	fluorocyclopentenylcytosine	8-38	DNA methyltransferase 1	Homo sapiens	67-90
32295203-0	2020	RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.	fluorocyclopentenylcytosine	8-38	TSC complex subunit 1	Homo sapiens	122-138
32295203-1	2020	(1) Background: RX-3117 (fluorocyclopentenyl-cytosine) is a cytidine analog that inhibits DNA methyltransferase 1 (DNMT1).	fluorocyclopentenylcytosine	25-53	DNA methyltransferase 1	Homo sapiens	90-113
32295203-1	2020	(1) Background: RX-3117 (fluorocyclopentenyl-cytosine) is a cytidine analog that inhibits DNA methyltransferase 1 (DNMT1).	fluorocyclopentenylcytosine	25-53	DNA methyltransferase 1	Homo sapiens	115-120
24940694-5	2014	The cytidine-analog fluorocyclopentenylcytosine (RX-3117) is active in gemcitabine-resistant tumors and is activated by uridine-cytidine-kinase, can be incorporated into RNA and DNA and can downregulate DNA-methyltransferase-1.	fluorocyclopentenylcytosine	20-47	DNA methyltransferase 1	Homo sapiens	203-226
24940694-5	2014	The cytidine-analog fluorocyclopentenylcytosine (RX-3117) is active in gemcitabine-resistant tumors and is activated by uridine-cytidine-kinase, can be incorporated into RNA and DNA and can downregulate DNA-methyltransferase-1.	fluorocyclopentenylcytosine	49-56	DNA methyltransferase 1	Homo sapiens	203-226
32295203-7	2020	In CEM/MTX cells, pre-treatment with RX-3117 increased PCFT-mediated MTX uptake 8-fold, and in CEM cells 4-fold.	fluorocyclopentenylcytosine	37-44	solute carrier family 46 member 1	Homo sapiens	55-59
32295203-11	2020	From the increased protein expression of tumor-suppressor genes and functional activation of PCFT, we concluded that RX-3117 might have induced hypomethylation of the promotor.	fluorocyclopentenylcytosine	117-124	TSC complex subunit 1	Homo sapiens	41-57
32295203-11	2020	From the increased protein expression of tumor-suppressor genes and functional activation of PCFT, we concluded that RX-3117 might have induced hypomethylation of the promotor.	fluorocyclopentenylcytosine	117-124	solute carrier family 46 member 1	Homo sapiens	93-97