PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
32331432-12	2020	Using a luciferase assay and western blot assay, we found that the NF-kappaB pathway was inhibited by Pg-EE, particularly by the decreased level of phosphorylated proteins of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) subunits (p65 and p50), inhibitor of kappa B alpha (IkappaBalpha), p85, and Src.	pg-ee	102-107	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	67-76
32331432-12	2020	Using a luciferase assay and western blot assay, we found that the NF-kappaB pathway was inhibited by Pg-EE, particularly by the decreased level of phosphorylated proteins of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) subunits (p65 and p50), inhibitor of kappa B alpha (IkappaBalpha), p85, and Src.	pg-ee	102-107	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	239-300
32331432-12	2020	Using a luciferase assay and western blot assay, we found that the NF-kappaB pathway was inhibited by Pg-EE, particularly by the decreased level of phosphorylated proteins of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) subunits (p65 and p50), inhibitor of kappa B alpha (IkappaBalpha), p85, and Src.	pg-ee	102-107	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	302-314
32331432-12	2020	Using a luciferase assay and western blot assay, we found that the NF-kappaB pathway was inhibited by Pg-EE, particularly by the decreased level of phosphorylated proteins of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) subunits (p65 and p50), inhibitor of kappa B alpha (IkappaBalpha), p85, and Src.	pg-ee	102-107	extracellular matrix protein 1	Mus musculus	317-320
32331432-12	2020	Using a luciferase assay and western blot assay, we found that the NF-kappaB pathway was inhibited by Pg-EE, particularly by the decreased level of phosphorylated proteins of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) subunits (p65 and p50), inhibitor of kappa B alpha (IkappaBalpha), p85, and Src.	pg-ee	102-107	Rous sarcoma oncogene	Mus musculus	326-329
32331432-13	2020	Using an overexpression strategy, cellular thermal shift assay, and immunoprecipitation analysis, we determined that the anti-inflammatory effect of Pg-EE was mediated by the inhibition of Src.	pg-ee	149-154	Rous sarcoma oncogene	Mus musculus	189-192
32331432-15	2020	In conclusion, Pg-EE exerts anti-inflammatory activities by targeting Src in the NF-kappaB pathway, and these results suggest that Pg-EE could be used as an anti-inflammatory herbal medicine.	pg-ee	15-20	Rous sarcoma oncogene	Mus musculus	70-73
32331432-15	2020	In conclusion, Pg-EE exerts anti-inflammatory activities by targeting Src in the NF-kappaB pathway, and these results suggest that Pg-EE could be used as an anti-inflammatory herbal medicine.	pg-ee	15-20	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90
32331432-15	2020	In conclusion, Pg-EE exerts anti-inflammatory activities by targeting Src in the NF-kappaB pathway, and these results suggest that Pg-EE could be used as an anti-inflammatory herbal medicine.	pg-ee	131-136	Rous sarcoma oncogene	Mus musculus	70-73
32331432-15	2020	In conclusion, Pg-EE exerts anti-inflammatory activities by targeting Src in the NF-kappaB pathway, and these results suggest that Pg-EE could be used as an anti-inflammatory herbal medicine.	pg-ee	131-136	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90
34500840-10	2021	Pg-EE can enhance the expression of filaggrin (FLG), transglutaminase (TGM)-1, hyaluronic acid synthase (HAS)-1, and HAS-2 in human keratinocytes.	pg-ee	0-5	filaggrin	Homo sapiens	36-45
34500840-10	2021	Pg-EE can enhance the expression of filaggrin (FLG), transglutaminase (TGM)-1, hyaluronic acid synthase (HAS)-1, and HAS-2 in human keratinocytes.	pg-ee	0-5	filaggrin	Homo sapiens	47-50
34500840-10	2021	Pg-EE can enhance the expression of filaggrin (FLG), transglutaminase (TGM)-1, hyaluronic acid synthase (HAS)-1, and HAS-2 in human keratinocytes.	pg-ee	0-5	transglutaminase 1	Homo sapiens	53-77
34500840-10	2021	Pg-EE can enhance the expression of filaggrin (FLG), transglutaminase (TGM)-1, hyaluronic acid synthase (HAS)-1, and HAS-2 in human keratinocytes.	pg-ee	0-5	hyaluronan synthase 1	Homo sapiens	79-111
34500840-10	2021	Pg-EE can enhance the expression of filaggrin (FLG), transglutaminase (TGM)-1, hyaluronic acid synthase (HAS)-1, and HAS-2 in human keratinocytes.	pg-ee	0-5	hyaluronan synthase 2	Homo sapiens	117-122
34500840-11	2021	Moreover, Pg-EE down-regulated the expression of pro-inflammatory cytokines and up-regulated the production of FLG, HAS-1, and HAS-2 suppressed by UVB through inhibition of p38 mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase (ERK) pathways.	pg-ee	10-15	filaggrin	Homo sapiens	111-114
34500840-11	2021	Moreover, Pg-EE down-regulated the expression of pro-inflammatory cytokines and up-regulated the production of FLG, HAS-1, and HAS-2 suppressed by UVB through inhibition of p38 mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase (ERK) pathways.	pg-ee	10-15	hyaluronan synthase 2	Homo sapiens	127-132