PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
6863313-1	1983	When 18-hydroxy-11-deoxycorticosterone was incubated with adrenocortical mitochondria fortified by adding exogenously adrenodoxin reductase and adrenodoxin in the presence of an NADPH-generating system, the steroid was converted to two products which were separated by high performance liquid chromatography.	18-Hydroxydesoxycorticosterone	5-38	ferredoxin reductase	Bos taurus	118-139
9461229-6	1998	18-Hydroxy-11-deoxycorticosterone (100 nmol/L), an adrenocorticoid hormone that is produced in greater amounts in S rats, stimulated Na+ transport by both S and R monolayers via the mineralocorticoid receptor; however, its effect was less potent than aldosterone.	18-Hydroxydesoxycorticosterone	0-33	nuclear receptor subfamily 3, group C, member 2	Rattus norvegicus	182-208
8312720-2	1993	Moreover, like adrenal quarters, they responded to angiotensin-II (Ang-II, 10(-8) M) by raising their yield of 18-hydroxylated steroids (18-hydroxy-11-deoxycorticosterone, 18-hydroxycorticosterone and aldosterone).	18-Hydroxydesoxycorticosterone	137-170	angiotensinogen	Rattus norvegicus	51-65
8312720-2	1993	Moreover, like adrenal quarters, they responded to angiotensin-II (Ang-II, 10(-8) M) by raising their yield of 18-hydroxylated steroids (18-hydroxy-11-deoxycorticosterone, 18-hydroxycorticosterone and aldosterone).	18-Hydroxydesoxycorticosterone	137-170	angiotensinogen	Rattus norvegicus	67-73
2070375-0	1991	Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients with increases of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone: a subtype of essential hypertension?	18-Hydroxydesoxycorticosterone	141-174	renin	Homo sapiens	50-55
7662589-3	1995	Under basal conditions, TGR had a moderately hypertrophic ZG, that showed a significantly higher secretion of 18-hydroxylated (18OH) steroids: 18-hydroxy-11-deoxycorticosterone (18OH-DOC), 18-hydroxycorticosterone (18OH-B) and aldosterone (ALDO); ZG cells of TGR showed angiotensin II (AII)-binding site concentrations and ALDO secretory responses to AII similar to those of SDR ZG cells.	18-Hydroxydesoxycorticosterone	143-176	thioredoxin reductase 3	Mus musculus	24-27
479350-1	1979	To assess the role of angiotensin II (AII) in regulating 18-hydroxy-11-deoxycorticosterone (18-OHDOC) secretion in man, isolated human adrenal glomerulosa cells were incubated with AII and/or its competitive antagonist, saralasin.	18-Hydroxydesoxycorticosterone	57-90	angiotensinogen	Homo sapiens	38-41
6277757-0	1981	18-hydroxy-11-deoxycorticosterone response to ACTH, insulin and furosemide administration in essential hypertensive patients.	18-Hydroxydesoxycorticosterone	0-33	proopiomelanocortin	Homo sapiens	46-50
6277757-1	1981	Investigations were carried out on the behavior of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH) under exogenous administration of synthetic ACTH and insulin.	18-Hydroxydesoxycorticosterone	51-84	proopiomelanocortin	Homo sapiens	172-176
6277757-1	1981	Investigations were carried out on the behavior of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH) under exogenous administration of synthetic ACTH and insulin.	18-Hydroxydesoxycorticosterone	51-84	insulin	Homo sapiens	181-188
7430311-3	1980	Both 18-hydroxycorticosterone and 18-hydroxy-11-deoxycorticosterone exhibited a marked loss of chromatographic efficiency when separated on incompletely-covered C18 reversed-phase supports (as determined by methyl red adsorption) showed no such effect, nor was it seen when aprotic solvents, such as dioxane, were used.	18-Hydroxydesoxycorticosterone	34-67	Bardet-Biedl syndrome 9	Homo sapiens	161-164
229997-0	1979	Radioimmunoassay of plasma 18-hydroxy-11-deoxycorticosterone and its response to ACTH.	18-Hydroxydesoxycorticosterone	27-60	proopiomelanocortin	Homo sapiens	81-85
870774-1	1977	Excess secretion of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) occurs in more than 10% of hypertensive patients with suppressed plasma renin activity, but it also is reported to occur in essential hypertension without impairment of the renin system.	18-Hydroxydesoxycorticosterone	20-53	renin	Homo sapiens	138-143
744066-0	1978	Stimulation of 18-hydroxy-11-deoxycorticosterone secretion by angiotensin II and potassium.	18-Hydroxydesoxycorticosterone	15-48	angiotensinogen	Rattus norvegicus	62-76
745404-0	1978	18-Hydroxy-11-deoxycorticosterone response to insulin in normal man.	18-Hydroxydesoxycorticosterone	0-33	insulin	Homo sapiens	46-53