PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 6863313-1 1983 When 18-hydroxy-11-deoxycorticosterone was incubated with adrenocortical mitochondria fortified by adding exogenously adrenodoxin reductase and adrenodoxin in the presence of an NADPH-generating system, the steroid was converted to two products which were separated by high performance liquid chromatography. 18-Hydroxydesoxycorticosterone 5-38 ferredoxin reductase Bos taurus 118-139 9461229-6 1998 18-Hydroxy-11-deoxycorticosterone (100 nmol/L), an adrenocorticoid hormone that is produced in greater amounts in S rats, stimulated Na+ transport by both S and R monolayers via the mineralocorticoid receptor; however, its effect was less potent than aldosterone. 18-Hydroxydesoxycorticosterone 0-33 nuclear receptor subfamily 3, group C, member 2 Rattus norvegicus 182-208 8312720-2 1993 Moreover, like adrenal quarters, they responded to angiotensin-II (Ang-II, 10(-8) M) by raising their yield of 18-hydroxylated steroids (18-hydroxy-11-deoxycorticosterone, 18-hydroxycorticosterone and aldosterone). 18-Hydroxydesoxycorticosterone 137-170 angiotensinogen Rattus norvegicus 51-65 8312720-2 1993 Moreover, like adrenal quarters, they responded to angiotensin-II (Ang-II, 10(-8) M) by raising their yield of 18-hydroxylated steroids (18-hydroxy-11-deoxycorticosterone, 18-hydroxycorticosterone and aldosterone). 18-Hydroxydesoxycorticosterone 137-170 angiotensinogen Rattus norvegicus 67-73 2070375-0 1991 Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients with increases of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone: a subtype of essential hypertension? 18-Hydroxydesoxycorticosterone 141-174 renin Homo sapiens 50-55 7662589-3 1995 Under basal conditions, TGR had a moderately hypertrophic ZG, that showed a significantly higher secretion of 18-hydroxylated (18OH) steroids: 18-hydroxy-11-deoxycorticosterone (18OH-DOC), 18-hydroxycorticosterone (18OH-B) and aldosterone (ALDO); ZG cells of TGR showed angiotensin II (AII)-binding site concentrations and ALDO secretory responses to AII similar to those of SDR ZG cells. 18-Hydroxydesoxycorticosterone 143-176 thioredoxin reductase 3 Mus musculus 24-27 479350-1 1979 To assess the role of angiotensin II (AII) in regulating 18-hydroxy-11-deoxycorticosterone (18-OHDOC) secretion in man, isolated human adrenal glomerulosa cells were incubated with AII and/or its competitive antagonist, saralasin. 18-Hydroxydesoxycorticosterone 57-90 angiotensinogen Homo sapiens 38-41 6277757-0 1981 18-hydroxy-11-deoxycorticosterone response to ACTH, insulin and furosemide administration in essential hypertensive patients. 18-Hydroxydesoxycorticosterone 0-33 proopiomelanocortin Homo sapiens 46-50 6277757-1 1981 Investigations were carried out on the behavior of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH) under exogenous administration of synthetic ACTH and insulin. 18-Hydroxydesoxycorticosterone 51-84 proopiomelanocortin Homo sapiens 172-176 6277757-1 1981 Investigations were carried out on the behavior of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH) under exogenous administration of synthetic ACTH and insulin. 18-Hydroxydesoxycorticosterone 51-84 insulin Homo sapiens 181-188 7430311-3 1980 Both 18-hydroxycorticosterone and 18-hydroxy-11-deoxycorticosterone exhibited a marked loss of chromatographic efficiency when separated on incompletely-covered C18 reversed-phase supports (as determined by methyl red adsorption) showed no such effect, nor was it seen when aprotic solvents, such as dioxane, were used. 18-Hydroxydesoxycorticosterone 34-67 Bardet-Biedl syndrome 9 Homo sapiens 161-164 229997-0 1979 Radioimmunoassay of plasma 18-hydroxy-11-deoxycorticosterone and its response to ACTH. 18-Hydroxydesoxycorticosterone 27-60 proopiomelanocortin Homo sapiens 81-85 870774-1 1977 Excess secretion of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) occurs in more than 10% of hypertensive patients with suppressed plasma renin activity, but it also is reported to occur in essential hypertension without impairment of the renin system. 18-Hydroxydesoxycorticosterone 20-53 renin Homo sapiens 138-143 744066-0 1978 Stimulation of 18-hydroxy-11-deoxycorticosterone secretion by angiotensin II and potassium. 18-Hydroxydesoxycorticosterone 15-48 angiotensinogen Rattus norvegicus 62-76 745404-0 1978 18-Hydroxy-11-deoxycorticosterone response to insulin in normal man. 18-Hydroxydesoxycorticosterone 0-33 insulin Homo sapiens 46-53