PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
26283899-11	2015	After administration of saline, REM was significantly greater in SES mice than in SIS mice whereas after CRF or AST, REM was similar in both groups.	ses	65-68	rad and gem related GTP binding protein 1	Mus musculus	32-35
26236183-5	2015	We find that V1rj2 and V1rj3 are sensitive to two sulfated estrogens (SEs) and can be activated by a broad variety of sulfated and glucuronidated steroids at high concentrations.	ses	70-73	vomeronasal 1 receptor 89	Mus musculus	13-18
26236183-5	2015	We find that V1rj2 and V1rj3 are sensitive to two sulfated estrogens (SEs) and can be activated by a broad variety of sulfated and glucuronidated steroids at high concentrations.	ses	70-73	vomeronasal 1 receptor 85	Mus musculus	23-28
25936917-2	2015	In embryonic stem cells (ESCs), SEs are highly enriched for the core pluripotency factors Oct4, Sox2, and Nanog.	ses	32-35	POU class 5 homeobox 1	Homo sapiens	90-94
25936917-2	2015	In embryonic stem cells (ESCs), SEs are highly enriched for the core pluripotency factors Oct4, Sox2, and Nanog.	ses	32-35	SRY-box transcription factor 2	Homo sapiens	96-100
25936917-5	2015	Tex10 is enriched at SEs in a Sox2-dependent manner and coordinates histone acetylation and DNA demethylation at SEs.	ses	21-24	testis expressed 10	Homo sapiens	0-5
25936917-5	2015	Tex10 is enriched at SEs in a Sox2-dependent manner and coordinates histone acetylation and DNA demethylation at SEs.	ses	21-24	SRY-box transcription factor 2	Homo sapiens	30-34
25936917-5	2015	Tex10 is enriched at SEs in a Sox2-dependent manner and coordinates histone acetylation and DNA demethylation at SEs.	ses	113-116	testis expressed 10	Homo sapiens	0-5
25936917-5	2015	Tex10 is enriched at SEs in a Sox2-dependent manner and coordinates histone acetylation and DNA demethylation at SEs.	ses	113-116	SRY-box transcription factor 2	Homo sapiens	30-34
25680776-6	2015	Remarkably, LIN5 and INH1 proteins were immunologically co-localized to cell walls of sieve elements (SEs) in ovaries immediately prior to anthesis and in young fruitlets, but were undetectable in provascular bundles of younger ovaries.	ses	102-105	beta-fructofuranosidase	Solanum lycopersicum	12-16
25483741-4	2015	Two ISR cases for SES showed a histopathological heterogeneity: one showed nodular calcified thrombus around stent strut protruding into the lumen, and the other showed concentric neointima composed of CD68-positive foam cell proliferation.	ses	18-21	CD68 molecule	Homo sapiens	202-206
25680776-10	2015	These new data indicate that (1) a phloem-specific patterning of the CWIN and INH mRNAs is induced during ovary-to-fruit transition, and (2) LIN5 protein functions specifically in walls of SEs and increases its activity during ovary-to-fruit transition, probably to facilitate phloem unloading and to generate a glucose signal positively regulating cell division, hence fruit set.	ses	189-192	beta-fructofuranosidase	Solanum lycopersicum	141-145
24462287-5	2014	Interfering with KIF13A function impairs the formation of endosomal tubules from SEs with consequent defects in endosome homeostasis and cargo recycling.	ses	81-84	kinesin family member 13A	Homo sapiens	17-23
25008404-1	2015	Subthreshold electrical stimulation (SES) has been shown to induce an improvement of angiogenesis in ischemic and nonischemic skeletal muscles, mediated by increased VEGF expression.	ses	37-40	vascular endothelial growth factor A	Homo sapiens	166-170
25008404-4	2015	Thus, we thought to investigate the effect of SES on VEGF regulation in cultured neonatal rat ventricular myocytes (NRVMs), in the aim to reveal new techniques for therapeutic angiogenesis in ischemic heart disease.	ses	46-49	vascular endothelial growth factor A	Rattus norvegicus	53-57
25008404-7	2015	To reveal the biological activity of the secreted VEGF amount, cultured human coronary artery endothelial cells (HCAECs) were treated with the cell culture supernatant of NRVMs exposed to SES.	ses	188-191	vascular endothelial growth factor A	Homo sapiens	50-54
25008404-12	2015	Cardiomyocytes respond to SES with an increase in biologically active VEGF expression that promotes cell proliferation of HCAECs.	ses	26-29	vascular endothelial growth factor A	Homo sapiens	70-74
24694903-6	2014	Analysis of skin equivalents (SEs) revealed a strong constitutive expression of S100 proteins in fetal but not in neonatal and adult SEs.	ses	30-33	S100 calcium binding protein B	Homo sapiens	80-84
24806562-3	2014	RESULTS: CCL3, CCL24, sTNFR1, and sTNFR2 were increased in SES and in SES with silicosis than in controls.	ses	59-62	C-C motif chemokine ligand 3	Homo sapiens	9-13
24806562-3	2014	RESULTS: CCL3, CCL24, sTNFR1, and sTNFR2 were increased in SES and in SES with silicosis than in controls.	ses	59-62	C-C motif chemokine ligand 24	Homo sapiens	15-20
24806562-3	2014	RESULTS: CCL3, CCL24, sTNFR1, and sTNFR2 were increased in SES and in SES with silicosis than in controls.	ses	70-73	C-C motif chemokine ligand 3	Homo sapiens	9-13
24806562-3	2014	RESULTS: CCL3, CCL24, sTNFR1, and sTNFR2 were increased in SES and in SES with silicosis than in controls.	ses	70-73	C-C motif chemokine ligand 24	Homo sapiens	15-20
25043067-3	2014	This study sought to evaluate the efficacy and safety of HELIOS completed biodegradable polymer sirolimus-eluting stent (SES) in de novo coronary lesions.	ses	121-124	IKAROS family zinc finger 2	Homo sapiens	57-63
25043067-12	2014	CONCLUSIONS: In the HOPE trial, the novel completed biodegradable polymer SES HELIOS was non-inferior to the durable polymer SES PARTNER with respect to nine-month in-stent LLL in de novo coronary lesions.	ses	74-77	IKAROS family zinc finger 2	Homo sapiens	78-84
23687436-13	2013	SES-treated eyes tended to have greater retinal Fgf2 expression than untreated eyes, but Fgf2 expression did not increase with IR light.	ses	0-3	fibroblast growth factor 2	Rattus norvegicus	48-52
23302112-13	2013	CONCLUSION: Serial measurement of plasma BNP levels and its change might be a useful approach to predict restenosis in patients without typical chest symptoms receiving SES.	ses	169-172	natriuretic peptide B	Homo sapiens	41-44
23336951-6	2013	In 2008, compared to BMS the SES was cost effective only in MVD db+ (7494$ per avoided revascularization (PAR) vs. >10,000$ in other groups).	ses	29-32	mevalonate diphosphate decarboxylase	Homo sapiens	60-63
23336951-7	2013	In 2012, after a reduction in the price difference between SES and BMS, SES were cost effective in MVD db+ (-891), SVD db+ (3519), MVD db- (3050), and SVD db- (6329) patients.	ses	72-75	mevalonate diphosphate decarboxylase	Homo sapiens	99-102
23336951-7	2013	In 2012, after a reduction in the price difference between SES and BMS, SES were cost effective in MVD db+ (-891), SVD db+ (3519), MVD db- (3050), and SVD db- (6329) patients.	ses	72-75	mevalonate diphosphate decarboxylase	Homo sapiens	131-134
23278857-6	2013	Shift-and-persist partially mediated the interaction of SES and role models on IL-6.	ses	56-59	interleukin 6	Homo sapiens	79-83
22819742-7	2012	Multiple regression analysis revealed that family history, statin administration, baseline serum creatinine, baseline "in-stent" thrombus, and follow-up LDL-C were significant determinants to the nominal change of yellow color grade after the SES implantation (p<0.0001).	ses	243-246	component of oligomeric golgi complex 2	Homo sapiens	153-158
23190888-6	2013	SEs also induced activation when we used epidermal cells from nonlesional skin of psoriatic patients with CLA(+) memory T cells.	ses	0-3	selectin P ligand	Homo sapiens	106-109
23453111-2	2013	Granulocyte colony-stimulating factor treatment might attenuate endothelial dysfunction after sirolimus-eluting stent (SES) implantation that may be associated with adverse cardiac events during follow-up.	ses	119-122	colony stimulating factor 3	Homo sapiens	0-37
23453111-3	2013	This prospective, double-blind, randomized, placebo-controlled study investigated whether G-CSF improved endothelial dysfunction after SES implantation.	ses	135-138	colony stimulating factor 3	Homo sapiens	90-95
23453111-11	2013	CONCLUSION: Granulocyte colony-stimulating factor attenuates endothelial dysfunction after SES implantation.	ses	91-94	colony stimulating factor 3	Homo sapiens	12-49
23078862-11	2013	When we divided study patients into acute coronary syndrome (ACS) or stable angina pectoris (SAP), there was a tendency toward less thrombus in EES than SES, in both ACS and SAP.	ses	153-156	SH2 domain containing 1A	Homo sapiens	93-96
22819742-8	2012	CONCLUSIONS: Serial change in tissue characteristics within residual plaque under SES is determined by several factors, especially LDL-C level as well as statin administration.	ses	82-85	component of oligomeric golgi complex 2	Homo sapiens	131-136
22819742-9	2012	Adequate management of LDL-C by statins might be crucial for stabilizing residual plaque after SES implantation.	ses	95-98	component of oligomeric golgi complex 2	Homo sapiens	23-28
22008318-2	2012	METHODS AND RESULTS: The Cypher Post-Marketing Surveillance Registry study has been conducted since August 2004 in Japan to evaluate the efficacy and safety of SES in a real-world setting.	ses	160-163	LIM domain binding 3	Homo sapiens	25-31
21666675-6	2011	The F&H binding site of OCRL is conserved even in species that do not have an identified homolog for APPL or Ses.	ses	113-116	OCRL inositol polyphosphate-5-phosphatase	Homo sapiens	28-32
21467171-8	2011	However, the expression of Fgf2 and Cntf was greater (6.5 +- 1.9- and 2.5 +- 0.5-fold, respectively; P < 0.02) in SES-treated mer(kd) retinas.	ses	117-120	fibroblast growth factor 2	Mus musculus	27-31
21467171-8	2011	However, the expression of Fgf2 and Cntf was greater (6.5 +- 1.9- and 2.5 +- 0.5-fold, respectively; P < 0.02) in SES-treated mer(kd) retinas.	ses	117-120	ciliary neurotrophic factor	Mus musculus	36-40
21467171-10	2011	CONCLUSIONS: Although SES upregulated Fgf2 in mer(kd) retinas, as reported previously for RCS retinas, this was not accompanied by neuroprotection of photoreceptors.	ses	22-25	fibroblast growth factor 2	Mus musculus	38-42
21633096-8	2011	RESULTS: Real-time PCR detected TLR1-6 messenger RNA expression in HPMC and responses to TLR2/1 and TLR2/6 ligands and SES.	ses	119-122	toll like receptor 1	Homo sapiens	32-38
21633096-10	2011	SES-mediated responses were dependent on TLR2 but did not require CD14 in HPMC for optimal efficiency, unlike peripheral blood mononuclear cells.	ses	0-3	toll like receptor 2	Homo sapiens	41-45
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	OCRL inositol polyphosphate-5-phosphatase	Homo sapiens	31-35
20485266-8	2010	Despite this observation which should be taken under consideration for clinical application, this preclinical study paves the way for a therapy based on grafting the most severely affected skin areas of patients with fully autologous SEs genetically corrected using a SIN COL7A1 retroviral vector.	ses	234-237	collagen type VII alpha 1 chain	Homo sapiens	272-278
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	Rho GTPase activating protein 1	Homo sapiens	40-46
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1	Homo sapiens	142-147
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	secernin 1	Homo sapiens	162-166
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	secernin 2	Homo sapiens	171-175
21666675-2	2011	Most missense mutations in the OCRL ASH-RhoGAP domain that are found in affected individuals abolish interactions with the endocytic adaptors APPL1 and Ses (both Ses1 and Ses2), which bind OCRL through a short phenylalanine and histidine (F&H) motif.	ses	152-155	OCRL inositol polyphosphate-5-phosphatase	Homo sapiens	189-193
21034557-14	2010	Levels of VCAM-1 in SES were significantly lower than those of PES and BMS (SES 0.35 +- 0.08 vs. PES 0.65 +- 0.13, BMS 0.70 +- 0.06, P < 0.05).	ses	20-23	vascular cell adhesion molecule 1	Sus scrofa	10-16
21034557-14	2010	Levels of VCAM-1 in SES were significantly lower than those of PES and BMS (SES 0.35 +- 0.08 vs. PES 0.65 +- 0.13, BMS 0.70 +- 0.06, P < 0.05).	ses	76-79	vascular cell adhesion molecule 1	Sus scrofa	10-16
21034557-15	2010	Histochemical immunostaining of vessel walls showed lower inflammatory chemokine MCP-1 expression in the SES and PES groups compared with BMS.	ses	105-108	C-C motif chemokine 2	Sus scrofa	81-86
21629364-16	2011	Compared to SIS mice, SES mice showed significantly increased REM after ST1 and ST2.	ses	22-25	interleukin 1 receptor-like 1	Mus musculus	80-83
21052690-11	2011	In conclusion, carriers of the 5352 A allele in the caspase-1 gene are at increased risk of developing LASM after SES implantation.	ses	114-117	caspase 1	Homo sapiens	52-61
20440486-5	2010	The extent of neointimal thickness, as measured by injury score, was significantly less in the SES group than in the BMS group (injury score 1: BMS 0.351 + or - 0.033 vs SES 0.226 + or - 0.031 mm; P < 0.01; injury score 2: BMS 1.232 + or - 0.244 vs SES 0.609 + or - 0.208 mm; P < 0.01).	ses	95-98	BMS1 ribosome biogenesis factor	Sus scrofa	226-231
20129572-1	2010	OBJECTIVES: In this study, we hypothesized that an antihuman-CD34 antibody immobilized on the surface of commercially available sirolimus-eluting stents (SES) could enhance re-endothelialization compared with SES alone.	ses	154-157	CD34 molecule	Sus scrofa	61-65
20129572-7	2010	In phase 2, SES-anti-CD34 resulted in increased endothelialization compared with SES alone at 3 days (SES-anti-CD34 36 +/- 26%; SES 7 +/- 3%; and GS 76 +/- 8%; p = 0.01), and 14 days (SES-anti-CD34 82 +/- 8%; SES 53 +/- 20%; and GS 98 +/- 2%; p = 0.009).	ses	12-15	CD34 molecule	Sus scrofa	21-25
20129572-7	2010	In phase 2, SES-anti-CD34 resulted in increased endothelialization compared with SES alone at 3 days (SES-anti-CD34 36 +/- 26%; SES 7 +/- 3%; and GS 76 +/- 8%; p = 0.01), and 14 days (SES-anti-CD34 82 +/- 8%; SES 53 +/- 20%; and GS 98 +/- 2%; p = 0.009).	ses	12-15	CD34 molecule	Sus scrofa	111-115
20129572-1	2010	OBJECTIVES: In this study, we hypothesized that an antihuman-CD34 antibody immobilized on the surface of commercially available sirolimus-eluting stents (SES) could enhance re-endothelialization compared with SES alone.	ses	209-212	CD34 molecule	Sus scrofa	61-65
20129572-7	2010	In phase 2, SES-anti-CD34 resulted in increased endothelialization compared with SES alone at 3 days (SES-anti-CD34 36 +/- 26%; SES 7 +/- 3%; and GS 76 +/- 8%; p = 0.01), and 14 days (SES-anti-CD34 82 +/- 8%; SES 53 +/- 20%; and GS 98 +/- 2%; p = 0.009).	ses	12-15	CD34 molecule	Sus scrofa	111-115
20129572-8	2010	CONCLUSIONS: Immobilization of anti-CD34 antibody on SES enhances endothelialization and may potentially be an effective therapeutic alternative to improve currently available drug-eluting stents.	ses	53-56	CD34 molecule	Sus scrofa	36-40
19387251-8	2009	CONCLUSION: The combination of elevated CRP and cTnI increased the risk of adverse cardiac events, demonstrating the additive impacts of active inflammation and myocardial injury on prognosis after SES implantation.	ses	198-201	C-reactive protein	Homo sapiens	40-43
19695219-1	2009	Previous studies have suggested a role for cytosolic Ca(2+)-independent phospholipase A(2) (PLA(2)) activity in the formation of endosome membrane tubules that participate in the export of transferrin (Tf) and transferrin receptors (TfR) from sorting endosomes (SEs) and the endocytic recycling compartment (ERC).	ses	262-265	phospholipase A2 group IB	Homo sapiens	72-90
19695219-1	2009	Previous studies have suggested a role for cytosolic Ca(2+)-independent phospholipase A(2) (PLA(2)) activity in the formation of endosome membrane tubules that participate in the export of transferrin (Tf) and transferrin receptors (TfR) from sorting endosomes (SEs) and the endocytic recycling compartment (ERC).	ses	262-265	phospholipase A2 group IB	Homo sapiens	92-98
19695219-1	2009	Previous studies have suggested a role for cytosolic Ca(2+)-independent phospholipase A(2) (PLA(2)) activity in the formation of endosome membrane tubules that participate in the export of transferrin (Tf) and transferrin receptors (TfR) from sorting endosomes (SEs) and the endocytic recycling compartment (ERC).	ses	262-265	transferrin	Homo sapiens	189-200
19695219-1	2009	Previous studies have suggested a role for cytosolic Ca(2+)-independent phospholipase A(2) (PLA(2)) activity in the formation of endosome membrane tubules that participate in the export of transferrin (Tf) and transferrin receptors (TfR) from sorting endosomes (SEs) and the endocytic recycling compartment (ERC).	ses	262-265	transferrin	Homo sapiens	202-204
19586494-2	2009	METHODS: Expression of p63 isoforms was examined in normal skin and hyperproliferative conditions including psoriasis and artificial skin equivalents (SEs).	ses	151-154	transformation related protein 63	Mus musculus	23-26
19387251-8	2009	CONCLUSION: The combination of elevated CRP and cTnI increased the risk of adverse cardiac events, demonstrating the additive impacts of active inflammation and myocardial injury on prognosis after SES implantation.	ses	198-201	troponin I3, cardiac type	Homo sapiens	48-52
18727076-10	2008	CONCLUSIONS: Compared with BMS, SES impair in-stent intima hyperplasia after stenting for acute myocardial infarction and transcoronary transplantation of G-CSF mobilized ASC.	ses	32-35	colony stimulating factor 3	Homo sapiens	155-160
19027437-7	2008	Preliminary regression analyses conducted with a small subset (n=15) of the patients receiving CBT showed those with relatively high levels of unhelpful sleep-related beliefs (Type 1 patients), as reflected by their pretherapy responses to the DBAS and SES questionnaires, showed markedly greater reductions in nocturnal wakefulness in response to CBT than did those (Type 2 patients) reporting less pronounced sleep-related beliefs.	ses	253-256	opsin 1, short wave sensitive	Homo sapiens	95-98
18803482-4	2009	SEs produced using SA cells and DSCs showed a thicker epidermis and higher expressions of alpha(6)- and beta1-integrin than SEs using SA cells and normal fibroblasts showed.	ses	0-3	integrin subunit beta 1	Homo sapiens	90-118
18803482-10	2009	Thus, the SEs with IGFBP-2 showed almost the same morphology of the SEs using DSCs.	ses	10-13	insulin like growth factor binding protein 2	Homo sapiens	19-26
18803482-10	2009	Thus, the SEs with IGFBP-2 showed almost the same morphology of the SEs using DSCs.	ses	68-71	insulin like growth factor binding protein 2	Homo sapiens	19-26
19245380-8	2009	At 24 hours, the mean plasma CRP concentration in the SES group was 20.21 mg/dL versus 8.95 mg/dL in the BMS group (P = 0.15).	ses	54-57	C-reactive protein	Homo sapiens	29-32
19245380-9	2009	The mean plasma IL-6 concentration at 24 hours was 25.41 pg/mL in the SES group versus 17.44 pg/mL in the BMS group (P = 0.17).	ses	70-73	interleukin 6	Homo sapiens	16-20
19245380-10	2009	The mean plasma MCP-1 concentration at 24 hours was 382.38 pg/mL in the SES group versus 329.04 pg/mL in the BMS group (P = 0.2).	ses	72-75	C-C motif chemokine ligand 2	Homo sapiens	16-21
18817526-6	2008	Pulse-chase studies indicate that Tf appears in G-clathrin structures in the cell periphery after sorting endosomes (SEs), but before filling of the perinuclear endocytic recycling compartment.	ses	117-120	transferrin	Homo sapiens	34-36
18817526-7	2008	Furthermore, the inhibitors LY294002 and wortmannin, which inhibit direct recycling of Tf from SEs to the plasma membrane, also block its appearance in G-clathrin.	ses	95-98	transferrin	Homo sapiens	87-89
18498145-7	2008	CONCLUSION: In this analysis, outcomes of insulin requiring diabetic patients undergoing PCI with SES were considerably improved with adjunctive GP IIb/IIIa inhibitors by decreasing the rates of MI and composite endpoint of cardiac death/MI.	ses	98-101	integrin subunit alpha 2b	Homo sapiens	145-151
19463300-11	2008	Change in lumen CSA was related to change in external elastic membrane CSA (R = 0.73, 95% CI 0.62 to 0.84) after SES implantation and to change in plaque and media CSA (R = -0.62, 95% CI -0.77 to -0.46) after BMS implantation.	ses	113-116	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	16-19
19463313-8	2008	Contraction to endothelin-1 was significantly enhanced for SES compared with both BMS and POLY.	ses	59-62	endothelin-1	Sus scrofa	15-27
18258405-6	2008	IGFBP-2, IGFBP-4 and IGFBP-6 mRNAs were all localised to the SES of inter-caruncular and caruncular uterine tissue, and in the DES and caruncular stroma, with IGFBP-4 mRNA additionally expressed in myometrium.	ses	61-64	insulin like growth factor binding protein 2	Bos taurus	0-7
18258405-6	2008	IGFBP-2, IGFBP-4 and IGFBP-6 mRNAs were all localised to the SES of inter-caruncular and caruncular uterine tissue, and in the DES and caruncular stroma, with IGFBP-4 mRNA additionally expressed in myometrium.	ses	61-64	insulin like growth factor binding protein 4	Bos taurus	9-16
18258405-6	2008	IGFBP-2, IGFBP-4 and IGFBP-6 mRNAs were all localised to the SES of inter-caruncular and caruncular uterine tissue, and in the DES and caruncular stroma, with IGFBP-4 mRNA additionally expressed in myometrium.	ses	61-64	insulin like growth factor binding protein 6	Bos taurus	21-28
18258405-8	2008	IGFBP-5 mRNA was found in myometrium, inter-caruncular and caruncular SES and caruncular stroma.	ses	70-73	insulin like growth factor binding protein 5	Bos taurus	0-7
17434617-1	2008	OBJECTIVE: This post-marketing surveillance registry is aimed at determining the safety and reliability of the CYPHER Select Sirolimus-eluting stent (SES) in routine clinical practice.	ses	150-153	LIM domain binding 3	Homo sapiens	111-117
17434617-2	2008	BACKGROUND: Little information and angiographic follow-up data in large-scale "real world" registry is available for the CYPHER Select SES, an advanced-generation SES.	ses	135-138	LIM domain binding 3	Homo sapiens	121-127
17434617-2	2008	BACKGROUND: Little information and angiographic follow-up data in large-scale "real world" registry is available for the CYPHER Select SES, an advanced-generation SES.	ses	163-166	LIM domain binding 3	Homo sapiens	121-127
17434617-9	2008	Angiographic follow-up at 9 months was performed in 418 (68.3%) lesions treated by CYPHER Select SES.	ses	97-100	LIM domain binding 3	Homo sapiens	83-89
17434617-14	2008	The safety and efficacy of CYPHER Select SES shown in this registry are consistent with those seen in SES studies.	ses	41-44	LIM domain binding 3	Homo sapiens	27-33
19463300-11	2008	Change in lumen CSA was related to change in external elastic membrane CSA (R = 0.73, 95% CI 0.62 to 0.84) after SES implantation and to change in plaque and media CSA (R = -0.62, 95% CI -0.77 to -0.46) after BMS implantation.	ses	113-116	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	71-74
19463300-11	2008	Change in lumen CSA was related to change in external elastic membrane CSA (R = 0.73, 95% CI 0.62 to 0.84) after SES implantation and to change in plaque and media CSA (R = -0.62, 95% CI -0.77 to -0.46) after BMS implantation.	ses	113-116	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	71-74
18389330-9	2008	Plasma Hu TNF-alpha levels at each time point were higher in the SES group than in the BMS and DEXES groups (P < 0.05).	ses	65-68	tumor necrosis factor	Homo sapiens	10-19
18364133-3	2008	This study was designed to evaluate the re-endothelialization and neointimal coverage of SES with OCT 6 months and 12 months after implantation.	ses	89-92	POU class 3 homeobox 1	Homo sapiens	98-103
17903627-9	2007	Vascular endothelial growth factor levels in the AIV were significantly lower than in the AO in the SES group but not in the BMS group.	ses	100-103	vascular endothelial growth factor A	Homo sapiens	0-34
18175998-8	2008	CONCLUSIONS: These data suggest that reduction in MCP-1 production by SES may be one mechanism to prevent restenosis after coronary stenting.	ses	70-73	C-C motif chemokine ligand 2	Homo sapiens	50-55
17986772-1	2007	SaPIN2a, a plant proteinase inhibitor from nightshade (Solanum americanum), was located to the enucleate sieve elements (SEs) of phloem.	ses	121-124	endogenous retrovirus group K member 18	Homo sapiens	17-27
17883323-5	2007	First, we showed that Langerin(+) mo-LC and dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (SIGN)(+) mo-DDCs were immunolocalized in situ in epidermal and dermal compartments of SEs, respectively.	ses	188-191	intercellular adhesion molecule 3	Homo sapiens	73-79
17903627-10	2007	CONCLUSIONS: During the course of AMI, SES implantation adversely affects endothelium-dependent vasomotor function in resistance and epicardial coronary arteries after the ischemia-reperfusion in association with a reduction in myocardial VEGF secretion.	ses	39-42	vascular endothelial growth factor A	Homo sapiens	239-243
16534015-12	2006	CONCLUSIONS: This analysis of 1-year data collected by the e-Cypher registry suggests a high degree of safety of SES, with a rate of stent thrombosis similar to that observed in randomized trials.	ses	113-116	LIM domain binding 3	Homo sapiens	61-67
17664110-8	2007	This effect of SES was associated with a smallest expression of the small G protein RhoA and an increase of p27kip expression.	ses	15-18	ras homolog family member A	Homo sapiens	84-88
17664110-13	2007	CONCLUSION: These results confirm the efficiency of sirolimus released form SES to inhibit RhoA expression and to increase p27kip level in the arterial wall and show the benefit of direct stenting to limit the edge effect with SES.	ses	76-79	ras homolog family member A	Homo sapiens	91-95
17052793-12	2007	SES could be a good strategy to prevent the G-CSF-stimulated proliferation and migration of smooth muscle cells, which could be responsible for neointimal hyperplasia.	ses	0-3	colony stimulating factor 3	Sus scrofa	44-49
16923447-9	2006	The same relation was present in the SES group, i.e., patients with a higher CRP level had a higher incidence of 12-month death or myocardial infarction compared with patients with a low CRP level (6.3% vs 1.0%, p = 0.005) and a higher 12-month mortality (5.2% vs 0%, p = 0.001).	ses	37-40	C-reactive protein	Homo sapiens	77-80
16923447-9	2006	The same relation was present in the SES group, i.e., patients with a higher CRP level had a higher incidence of 12-month death or myocardial infarction compared with patients with a low CRP level (6.3% vs 1.0%, p = 0.005) and a higher 12-month mortality (5.2% vs 0%, p = 0.001).	ses	37-40	C-reactive protein	Homo sapiens	187-190
16923447-11	2006	In conclusion, PCI in the SES era causes a smaller increase in CRP compared with the BMS era.	ses	26-29	C-reactive protein	Homo sapiens	63-66
17849409-2	2007	In this work, proteomic analysis together with ligand blotting assays identified several major Plg-binding spots in Mycobacterium tuberculosis soluble extracts (SEs) and culture filtrate proteins.	ses	161-164	plasminogen	Homo sapiens	95-98
17216343-7	2007	This study suggests that different SES classes may modify the effect of the functional variant(s) in and around BDNF to have an impact on the number of ADHD symptom counts that are observed.	ses	35-38	brain derived neurotrophic factor	Homo sapiens	112-116
17276176-11	2007	A significant reduction in PSPA% was observed with SES (-4 +/- 10% vs. 0 +/- 8%; p = 0.01).	ses	51-54	surfactant protein A2	Homo sapiens	27-32
16198206-1	2005	Antisense oligodeoxynucleotide against the splicing enhancer sequence (SES) in exon 19 of the dystrophin gene have been shown to induce exon 19 skipping and promote the expression of internally deleted dystrophin by correcting the translational reading frame in the cultured Duchenne muscular dystrophy (DMD) myocytes with the deletion of exon 20.	ses	71-74	dystrophin, muscular dystrophy	Mus musculus	94-104
16209986-2	2005	We evaluated the impact of SES implantation on immediate and 12-month outcome in diabetic patients with multivessel coronary artery disease (MVD).	ses	27-30	mevalonate diphosphate decarboxylase	Homo sapiens	141-144
16209986-10	2005	CONCLUSIONS: As compared with BS implantation, SES implantation favorably influences outcome in diabetic patients with MVD, mainly by reducing the need for new revascularization.	ses	47-50	mevalonate diphosphate decarboxylase	Homo sapiens	119-122
16198206-1	2005	Antisense oligodeoxynucleotide against the splicing enhancer sequence (SES) in exon 19 of the dystrophin gene have been shown to induce exon 19 skipping and promote the expression of internally deleted dystrophin by correcting the translational reading frame in the cultured Duchenne muscular dystrophy (DMD) myocytes with the deletion of exon 20.	ses	71-74	dystrophin, muscular dystrophy	Mus musculus	202-212
15940356-6	2005	There was an absolute decrease in target lesion revascularization of 17% (95% CI 14% to 20%), 9% (95% CI 6% to 11%) and 3% (95% CI 0% to 6%) with SES, PPOL and PNPOL, respectively, with significant differences between SES and PPOL and between PPOL and PNPOL (P < 0.01 for both comparisons).	ses	146-149	poly(ADP-ribose) polymerase 1	Homo sapiens	151-155
15940356-6	2005	There was an absolute decrease in target lesion revascularization of 17% (95% CI 14% to 20%), 9% (95% CI 6% to 11%) and 3% (95% CI 0% to 6%) with SES, PPOL and PNPOL, respectively, with significant differences between SES and PPOL and between PPOL and PNPOL (P < 0.01 for both comparisons).	ses	146-149	poly(ADP-ribose) polymerase 1	Homo sapiens	226-230
15940356-6	2005	There was an absolute decrease in target lesion revascularization of 17% (95% CI 14% to 20%), 9% (95% CI 6% to 11%) and 3% (95% CI 0% to 6%) with SES, PPOL and PNPOL, respectively, with significant differences between SES and PPOL and between PPOL and PNPOL (P < 0.01 for both comparisons).	ses	146-149	poly(ADP-ribose) polymerase 1	Homo sapiens	226-230
15940356-6	2005	There was an absolute decrease in target lesion revascularization of 17% (95% CI 14% to 20%), 9% (95% CI 6% to 11%) and 3% (95% CI 0% to 6%) with SES, PPOL and PNPOL, respectively, with significant differences between SES and PPOL and between PPOL and PNPOL (P < 0.01 for both comparisons).	ses	218-221	poly(ADP-ribose) polymerase 1	Homo sapiens	151-155
15667001-8	2004	We observed a possible trend for certain unfavorable prognostic parameters (e.g., young women, low-graded tumors, human epidermal growth factor receptor 2 overexpression) to be related to higher serum levels of sES.	ses	211-214	erb-b2 receptor tyrosine kinase 2	Homo sapiens	120-154
10996561-3	2000	No specific treatment has been advocated for this syndrome, but valproate sodium, benzodiazepines and ACTH have been shown to control the seizures and the SES pattern in many cases, although often only temporarily.	ses	155-158	proopiomelanocortin	Homo sapiens	102-106
12866772-2	2003	From a recent study, the sirolimus eluting stent (SES) (CYPHER, Cordis, Johnson & Johnson) appear to demonstrate a remarkable efficacy and safety in preventing restenosis.	ses	50-53	LIM domain binding 3	Homo sapiens	56-62
12586740-8	2003	Infarct size decreased, whereas SES improved after either VEGF or eNOS S1177D transfection, an effect inhibited by L-NAME coapplication.	ses	32-35	vascular endothelial growth factor A	Sus scrofa	58-62
12145004-1	2002	BACKGROUND: Naturally occurring plant sterol esters (SEs) favorably affect serum cholesterol concentrations in humans and could aid in the treatment of children with familial hypercholesterolemia (FH).	ses	53-56	low density lipoprotein receptor	Homo sapiens	166-195
12145004-1	2002	BACKGROUND: Naturally occurring plant sterol esters (SEs) favorably affect serum cholesterol concentrations in humans and could aid in the treatment of children with familial hypercholesterolemia (FH).	ses	53-56	low density lipoprotein receptor	Homo sapiens	197-199
12145004-3	2002	DESIGN: In a randomized, double-blind crossover study comprising two 8-wk interventions, 38 children with FH consumed 18.2 +/- 1.5 g SE spread/d, corresponding to 1.60 +/- 0.13 g SEs, or a control spread.	ses	179-182	low density lipoprotein receptor	Homo sapiens	106-108
12145004-12	2002	CONCLUSION: A daily intake of 1.6 g SEs induces an additional reduction in LDL-cholesterol concentrations in children with FH consuming a recommended diet.	ses	36-39	low density lipoprotein receptor	Homo sapiens	123-125
12061080-8	2002	The expression of adhesion molecules on PBMCs: After 3- and 6-months of SeS, a decreased expression of molecules CD11a, CD11b and CD62L was observed (p < 0.02, p < 0.005, p < 0.003).	ses	72-75	integrin subunit alpha L	Homo sapiens	113-118
12061080-8	2002	The expression of adhesion molecules on PBMCs: After 3- and 6-months of SeS, a decreased expression of molecules CD11a, CD11b and CD62L was observed (p < 0.02, p < 0.005, p < 0.003).	ses	72-75	integrin subunit alpha M	Homo sapiens	120-125
12061080-8	2002	The expression of adhesion molecules on PBMCs: After 3- and 6-months of SeS, a decreased expression of molecules CD11a, CD11b and CD62L was observed (p < 0.02, p < 0.005, p < 0.003).	ses	72-75	selectin L	Homo sapiens	130-135
12061080-12	2002	Soluble adhesion molecules: After 3 months of SeS we noticed a significant decrease in VCAM-1 and P-selectin expressions (p < 0.05, p < 0.05) and after 6 months the level of VCAM-1 decreased (p < 0.01).	ses	46-49	vascular cell adhesion molecule 1	Homo sapiens	87-93
12061080-12	2002	Soluble adhesion molecules: After 3 months of SeS we noticed a significant decrease in VCAM-1 and P-selectin expressions (p < 0.05, p < 0.05) and after 6 months the level of VCAM-1 decreased (p < 0.01).	ses	46-49	selectin P	Homo sapiens	98-108
12061080-12	2002	Soluble adhesion molecules: After 3 months of SeS we noticed a significant decrease in VCAM-1 and P-selectin expressions (p < 0.05, p < 0.05) and after 6 months the level of VCAM-1 decreased (p < 0.01).	ses	46-49	vascular cell adhesion molecule 1	Homo sapiens	180-186
12061081-7	2002	RESULTS: Epitopes EG1 and EG2 in cytoplasma of Eo decreased significantly after 12 weeks of SeS, (p < 0.01) and 96 weeks of follow up.	ses	92-95	mediator complex subunit 28	Homo sapiens	18-21
11769384-11	2001	Significant correlation between plasma vWF:Ag and serum sES concentration was also observed (Rs = 0.501, p < 0.001).	ses	56-59	von Willebrand factor	Homo sapiens	39-42
1881894-1	1991	We investigated whether staphylococcal exotoxins (SEs), in addition to their capacity to induce T-cell activation restricted by the T-cell receptor (TCR) beta-chain variable region, can deliver an activation signal to human T-cell clones through major histocompatibility complex (MHC) class II molecules.	ses	50-53	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	132-147
10509575-16	1999	Eight of 11 MOS-HIV sub-scales and the Mental Health Summary Score were responsive to change (SES, 0.18-0.36), compared with six of 10 MQOL-HIV sub-scales and MQOL Index (SES, 0.16-0.27).	ses	94-97	MOS proto-oncogene, serine/threonine kinase	Homo sapiens	12-15
9331321-10	1997	IL-8-injected ears histologically demonstrated thickening of the epithelial layer and subepithelial space (SES), with inflammatory cell infiltration in the SES peaking at 4 to 8 hours and resolving by 48 hours.	ses	107-110	chemokine (C-X-C motif) ligand 15	Mus musculus	0-4
9331321-10	1997	IL-8-injected ears histologically demonstrated thickening of the epithelial layer and subepithelial space (SES), with inflammatory cell infiltration in the SES peaking at 4 to 8 hours and resolving by 48 hours.	ses	156-159	chemokine (C-X-C motif) ligand 15	Mus musculus	0-4
1464655-5	1992	In both groups there was a significant increase in scores in the Psychosexual Stimulation Scale of the SES (i.e. SES 2) following testosterone administration, but not with placebo.	ses	103-106	secernin 2	Homo sapiens	113-118
9036853-3	1997	SUT1 protein was detected by immunolocalization in plasma membranes of enucleate sieve elements (SEs) in tobacco, potato, and tomato.	ses	97-100	sucrose transport protein-like	Nicotiana tabacum	0-4
8455451-11	1993	Citrate synthase activity was significantly increased after SES.	ses	60-63	citrate synthase	Macaca mulatta	0-16
1881894-1	1991	We investigated whether staphylococcal exotoxins (SEs), in addition to their capacity to induce T-cell activation restricted by the T-cell receptor (TCR) beta-chain variable region, can deliver an activation signal to human T-cell clones through major histocompatibility complex (MHC) class II molecules.	ses	50-53	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	149-152
34719039-3	2021	Using de novo motif analysis, we show that the hepatocyte nuclear factor 1 (HNF1)-binding motif is enriched in SEs in cell lines derived from liver metastases, but not in those from primary tumors.	ses	111-114	HNF1 homeobox A	Homo sapiens	47-74
34719039-3	2021	Using de novo motif analysis, we show that the hepatocyte nuclear factor 1 (HNF1)-binding motif is enriched in SEs in cell lines derived from liver metastases, but not in those from primary tumors.	ses	111-114	HNF1 homeobox A	Homo sapiens	76-80
32111830-5	2020	Mechanistically, we show a pivotal role for ESRRB in regulating the activity of ESC-specific enhancer units and propose that the developmentally regulated silencing of ESRRB triggers the selective inactivation of these units within SEs.	ses	232-235	estrogen related receptor beta	Homo sapiens	44-49
32199616-2	2020	Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers.	ses	83-86	bromodomain containing 4	Homo sapiens	52-56
32111671-7	2020	Under this regulatory scheme, NARS1, generated in the CCs of the root differentiation zone, establishes a top-down signal to drive the ACD for phloem SEs in the meristem.	ses	150-153	NAC domain containing protein 2	Arabidopsis thaliana	30-35
32111830-5	2020	Mechanistically, we show a pivotal role for ESRRB in regulating the activity of ESC-specific enhancer units and propose that the developmentally regulated silencing of ESRRB triggers the selective inactivation of these units within SEs.	ses	232-235	estrogen related receptor beta	Homo sapiens	168-173
32120995-4	2020	In this paper, we show that the construction of estrogen receptor alpha-driven SEs is tissue-specific, both collaborating TFs and the active SE components greatly differ between human breast cancer-derived MCF-7 and endometrial cancer-derived Ishikawa cells; nonetheless, SEs common to both cell lines have similar transcriptional outputs.	ses	79-82	estrogen receptor 1	Homo sapiens	48-71
32120995-4	2020	In this paper, we show that the construction of estrogen receptor alpha-driven SEs is tissue-specific, both collaborating TFs and the active SE components greatly differ between human breast cancer-derived MCF-7 and endometrial cancer-derived Ishikawa cells; nonetheless, SEs common to both cell lines have similar transcriptional outputs.	ses	272-275	estrogen receptor 1	Homo sapiens	48-71
31026991-9	2019	In addition, the levels of COX-2, TNF-alpha and IL-6 significantly decreased after SES treatment.	ses	83-86	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	27-32
31026991-9	2019	In addition, the levels of COX-2, TNF-alpha and IL-6 significantly decreased after SES treatment.	ses	83-86	tumor necrosis factor	Rattus norvegicus	34-43
31026991-9	2019	In addition, the levels of COX-2, TNF-alpha and IL-6 significantly decreased after SES treatment.	ses	83-86	interleukin 6	Rattus norvegicus	48-52
31105558-6	2019	Moreover, several clinical trials on novel SEs blockers, such as BET inhibitor and CDK7i, have indicated the potential roles of SEs in cancer therapy.	ses	43-46	delta/notch like EGF repeat containing	Homo sapiens	65-68
31285436-3	2019	In alveolar rhabdomyosarcoma, PAX3-FOXO1 activates SEs to induce the expression of other CR TFs, providing a model system for studying cancer cell addiction to CR transcription.	ses	51-54	paired box 3	Homo sapiens	30-34
31285436-3	2019	In alveolar rhabdomyosarcoma, PAX3-FOXO1 activates SEs to induce the expression of other CR TFs, providing a model system for studying cancer cell addiction to CR transcription.	ses	51-54	forkhead box O1	Homo sapiens	35-40
30876920-8	2019	RESULTS: SR-B1 knockdown resulted in decreased lipid levels in SEs, specifically ceramides, and in decreased transcript levels of LDLR, PPAR-alpha and PPAR-gamma, which are factors involved in regulating ceramide synthesis.	ses	63-66	scavenger receptor class B member 1	Homo sapiens	9-14
30604489-7	2019	Immunolocalization analysis indicated that CsGolS1 was localized in companion cells (CCs) while CsSUT2 was in CCs and sieve elements (SEs).	ses	134-137	sucrose transport protein SUC3	Cucumis sativus	96-102
30466442-2	2018	Inhibition of BRD4 shortcuts the communication between SEs and target promoters with a subsequent cell-specific repression of oncogenes to which cancer cells are addicted and cell death.	ses	55-58	bromodomain containing 4	Homo sapiens	14-18
30474248-7	2019	By immunohistochemistry, FOSL1 showed an intense staining at the invasive front of cSCC samples and BNC1 expression varied from a nuclear (SES) to a cytoplasmic location (cSCC).	ses	139-142	basonuclin 1	Homo sapiens	100-104
29571163-2	2018	The SES was fabricated by covalent binding of tri-enzymes, adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and xanthine oxidase (XO) along with hydrazine (Hyd) onto a functionalized conducting polymer [2,2:5,2-terthiophene-3-(p-benzoic acid)] (pTTBA).	ses	4-7	adenosine deaminase	Chlorocebus sabaeus	59-78
30364099-3	2018	Results showed that application of burst-like SES to rat toes produced (i) rapid induction of hyperalgesia that lasted for more than 3 weeks, (ii) early increase of C-reflex activity followed by increased wind-up scores lasting for more than 1 week, and (iii) early increase followed by late decrease in BDNF protein levels and phosphorylated TrkB that lasted for more than 1 week.	ses	46-49	brain-derived neurotrophic factor	Rattus norvegicus	304-308
30364099-3	2018	Results showed that application of burst-like SES to rat toes produced (i) rapid induction of hyperalgesia that lasted for more than 3 weeks, (ii) early increase of C-reflex activity followed by increased wind-up scores lasting for more than 1 week, and (iii) early increase followed by late decrease in BDNF protein levels and phosphorylated TrkB that lasted for more than 1 week.	ses	46-49	neurotrophic receptor tyrosine kinase 2	Rattus norvegicus	343-347
30154210-6	2018	Rab4A localizes to the SEs and forms an endosomal complex with the adaptor AP-3, the effector rabenosyn-5 and the motor KIF3, which possibly coordinates cargo segregation on SEs.	ses	23-26	RAB4A, member RAS oncogene family	Homo sapiens	0-5
30154210-6	2018	Rab4A localizes to the SEs and forms an endosomal complex with the adaptor AP-3, the effector rabenosyn-5 and the motor KIF3, which possibly coordinates cargo segregation on SEs.	ses	174-177	RAB4A, member RAS oncogene family	Homo sapiens	0-5
30154210-6	2018	Rab4A localizes to the SEs and forms an endosomal complex with the adaptor AP-3, the effector rabenosyn-5 and the motor KIF3, which possibly coordinates cargo segregation on SEs.	ses	174-177	rabenosyn, RAB effector	Homo sapiens	94-105
30154210-8	2018	Further, rabenosyn-5 was found to associate with rabaptin-5 or Rabip4/4" (isoforms encoded by Rufy1) and differentially regulate cargo sorting from SEs.	ses	148-151	rabenosyn, RAB effector	Homo sapiens	9-20
30154210-9	2018	Thus, Rab4A acts a key regulator of cargo segregation on SEs.This article has an associated First Person interview with the first author of the paper.	ses	57-60	RAB4A, member RAS oncogene family	Homo sapiens	6-11
29930091-2	2018	Here we demonstrate that the SE-enriched transcriptional coactivators BRD4 and MED1 form nuclear puncta at SEs that exhibit properties of liquid-like condensates and are disrupted by chemicals that perturb condensates.	ses	107-110	bromodomain containing 4	Homo sapiens	70-74
29930091-2	2018	Here we demonstrate that the SE-enriched transcriptional coactivators BRD4 and MED1 form nuclear puncta at SEs that exhibit properties of liquid-like condensates and are disrupted by chemicals that perturb condensates.	ses	107-110	mediator complex subunit 1	Homo sapiens	79-83
29877698-9	2018	These results suggest that the development of electrochemically more stable SEs and the engineering of cathode/SE interfaces are crucial for achieving reliable SSB performance.	ses	76-79	small RNA binding exonuclease protection factor La	Homo sapiens	160-163
29315616-3	2018	Recently, increased rates of elevated levels of IgE towards Staphylococcus aureus enterotoxins (SEs) were described in CSU.	ses	96-99	immunoglobulin heavy constant epsilon	Homo sapiens	48-51
29315616-4	2018	AIM: To assess the prevalence and functional relevance of IgE to SEs in CSU.	ses	65-68	immunoglobulin heavy constant epsilon	Homo sapiens	58-61
29315616-8	2018	Specific IgE to one of the SEs, Staphylococcus enterotoxin B (SEB), was present in 5 (33%) of 15 randomly selected CSU patients vs 3 (20%) of HC.	ses	27-30	immunoglobulin heavy constant epsilon	Homo sapiens	9-12
29315616-12	2018	DISCUSSION: IgE against SEs may contribute to the pathogenesis of CSU in a subpopulation of patients.	ses	24-27	immunoglobulin heavy constant epsilon	Homo sapiens	12-15
30146162-3	2018	Oncogene-driving super-enhancers (SEs) are highly sensitive to CDK7/9 inhibition.	ses	34-37	cyclin dependent kinase 7	Homo sapiens	63-67
29571163-2	2018	The SES was fabricated by covalent binding of tri-enzymes, adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and xanthine oxidase (XO) along with hydrazine (Hyd) onto a functionalized conducting polymer [2,2:5,2-terthiophene-3-(p-benzoic acid)] (pTTBA).	ses	4-7	adenosine deaminase	Chlorocebus sabaeus	80-83
29571163-2	2018	The SES was fabricated by covalent binding of tri-enzymes, adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and xanthine oxidase (XO) along with hydrazine (Hyd) onto a functionalized conducting polymer [2,2:5,2-terthiophene-3-(p-benzoic acid)] (pTTBA).	ses	4-7	purine nucleoside phosphorylase	Chlorocebus sabaeus	86-117
29571163-2	2018	The SES was fabricated by covalent binding of tri-enzymes, adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and xanthine oxidase (XO) along with hydrazine (Hyd) onto a functionalized conducting polymer [2,2:5,2-terthiophene-3-(p-benzoic acid)] (pTTBA).	ses	4-7	purine nucleoside phosphorylase	Chlorocebus sabaeus	119-122
29428186-12	2018	Taken together, these results indicate that YIGSR promotes the reconstruction of SEs, potentially via decreased TGF-beta1 levels and consequent inhibition of epidermal differentiation.	ses	81-84	transforming growth factor beta 1	Homo sapiens	112-121
29339447-2	2018	Here we demonstrate that formation of super-enhancers (SEs) is critical in robust induction of IL-9 and that assembly of the Il9 SEs in Th cells requires OX40-triggered chromatin acetylation.	ses	55-58	interleukin 9	Homo sapiens	95-99
29339447-2	2018	Here we demonstrate that formation of super-enhancers (SEs) is critical in robust induction of IL-9 and that assembly of the Il9 SEs in Th cells requires OX40-triggered chromatin acetylation.	ses	129-132	interleukin 9	Homo sapiens	125-128
29339447-2	2018	Here we demonstrate that formation of super-enhancers (SEs) is critical in robust induction of IL-9 and that assembly of the Il9 SEs in Th cells requires OX40-triggered chromatin acetylation.	ses	129-132	TNF receptor superfamily member 4	Homo sapiens	154-158
29339447-6	2018	Together, our data suggest that formation of SEs is essential in IL-9 expression and Th9 cell induction.	ses	45-48	interleukin 9	Homo sapiens	65-69
28480624-3	2017	Herein, highly conductive (0.14 mS cm-1 ) and dry-air-stable SEs (Li4 SnS4 ) are reported, which are prepared using a scalable aqueous-solution process.	ses	61-64	lipase family member N	Homo sapiens	66-69
29886244-17	2018	CONCLUSIONS: In this sample, intrauterine co-exposure to MJ and TOB was associated with an estimated 18% reduction in birth weight not attributable to earlier delivery, exposure to ALC or OTH drugs, nor to maternal SES.	ses	215-218	transducer of ERBB2, 1	Homo sapiens	64-67
28398509-5	2017	Further, MLL4 and CBP identify super-enhancers (SEs) of adipogenesis and that MLL3/MLL4 are required for SE formation.	ses	48-51	lysine (K)-specific methyltransferase 2D	Mus musculus	9-13
28398509-5	2017	Further, MLL4 and CBP identify super-enhancers (SEs) of adipogenesis and that MLL3/MLL4 are required for SE formation.	ses	48-51	CREB binding protein	Mus musculus	18-21
28398509-6	2017	Finally, in brown adipocytes differentiated in culture, MLL4 identifies primed SEs of genes fully activated in BAT such as Ucp1.	ses	79-82	lysine (K)-specific methyltransferase 2D	Mus musculus	56-60
28398509-6	2017	Finally, in brown adipocytes differentiated in culture, MLL4 identifies primed SEs of genes fully activated in BAT such as Ucp1.	ses	79-82	uncoupling protein 1 (mitochondrial, proton carrier)	Mus musculus	123-127
28398509-7	2017	Comparison of MLL4-defined SEs in brown and white adipogenesis identifies brown-specific SE-associated genes that could be involved in BAT functions.	ses	27-30	lysine (K)-specific methyltransferase 2D	Mus musculus	14-18
26526816-6	2016	However, the vasomotor response was impaired and the VEGF level of the coronary sinus was significantly lower in SES than in EES and ZES.	ses	113-116	vascular endothelial growth factor A	Homo sapiens	53-57
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	80-83	CD47 molecule	Homo sapiens	75-79
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	80-83	CD47 molecule	Homo sapiens	94-98
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	80-83	CD47 molecule	Homo sapiens	94-98
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	80-83	CD47 molecule	Homo sapiens	94-98
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	169-172	CD47 molecule	Homo sapiens	75-79
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	169-172	CD47 molecule	Homo sapiens	94-98
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	169-172	CD47 molecule	Homo sapiens	94-98
28378740-5	2017	We show that a set of active constituent enhancers, located within the two CD47 SEs, regulate CD47 expression in different cancer cell types and that disruption of CD47 SEs reduces CD47 gene expression.	ses	169-172	CD47 molecule	Homo sapiens	94-98
27425608-5	2016	A miR-9 mimic represses stimulus-dependent targeting of BRD4 to SEs and blunts Pol II phosphorylation at proximal transcription start sites, without affecting BRD4 binding to SEs that control constitutively expressed cardiac genes.	ses	64-67	MLX interacting protein	Homo sapiens	2-5
27529175-12	2016	Pain ratings to SES were reliable, but with large estimated sample sizes (Ncr = 634, Np = 11310) due to the minor pain amplification.	ses	16-19	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	74-77
27425608-5	2016	A miR-9 mimic represses stimulus-dependent targeting of BRD4 to SEs and blunts Pol II phosphorylation at proximal transcription start sites, without affecting BRD4 binding to SEs that control constitutively expressed cardiac genes.	ses	64-67	bromodomain containing 4	Homo sapiens	56-60
25863806-12	2016	These data suggested that serum CysC level is an independent predictor of MACCE, even in patients with preserved eGFR after elective SES implantation.	ses	133-136	cystatin C	Homo sapiens	32-36
27340176-7	2016	Mechanistically, Ino80 occupies >90% of SEs, and its occupancy is dependent on transcription factors such as MITF and Sox9.	ses	43-46	INO80 complex ATPase subunit	Homo sapiens	17-22
27340176-7	2016	Mechanistically, Ino80 occupies >90% of SEs, and its occupancy is dependent on transcription factors such as MITF and Sox9.	ses	43-46	melanocyte inducing transcription factor	Homo sapiens	112-116
27340176-7	2016	Mechanistically, Ino80 occupies >90% of SEs, and its occupancy is dependent on transcription factors such as MITF and Sox9.	ses	43-46	SRY-box transcription factor 9	Homo sapiens	121-125
27340176-10	2016	Together, our results reveal an essential role of INO80-dependent chromatin remodeling in SE function and suggest a novel strategy for disrupting SEs in cancer treatment.	ses	146-149	INO80 complex ATPase subunit	Homo sapiens	50-55
26646290-6	2016	We also found that N-acetyl-l-cysteine (NAC), a reactive oxygen species scavenger, antagonized the hypoxia-induced reduction of K1/K10 in keratinocytes and SEs.	ses	156-159	X-linked Kx blood group	Homo sapiens	40-43
26146941-6	2015	We also demonstrated that wheat aspartic protease (WAP1) and proteases including cathepsin B activity (PICA) were involved in programmed cell semi-death of SEs.	ses	156-159	phytepsin	Triticum aestivum	51-55
26146941-6	2015	We also demonstrated that wheat aspartic protease (WAP1) and proteases including cathepsin B activity (PICA) were involved in programmed cell semi-death of SEs.	ses	156-159	cathepsin B-like protease 2	Triticum aestivum	81-92
26636534-9	2015	CONCLUSIONS: SES can execute a protective role in SCI through up-regulating the expression of CNTF and CNTF-Ralpha.	ses	13-16	ciliary neurotrophic factor	Rattus norvegicus	94-98
26636534-9	2015	CONCLUSIONS: SES can execute a protective role in SCI through up-regulating the expression of CNTF and CNTF-Ralpha.	ses	13-16	ciliary neurotrophic factor receptor	Rattus norvegicus	103-114
26546038-4	2015	Previously, SEs have been defined as having the highest density of Med1, Brd4 or H3K27ac by ChIP-seq.	ses	12-15	mediator complex subunit 1	Homo sapiens	67-71
26546038-4	2015	Previously, SEs have been defined as having the highest density of Med1, Brd4 or H3K27ac by ChIP-seq.	ses	12-15	bromodomain containing 4	Homo sapiens	73-77
26546038-5	2015	The histone acetyltransferase P300 has been used as a marker of enhancers, but little is known about its binding to SEs.	ses	116-119	E1A binding protein p300	Homo sapiens	4-34
26546038-12	2015	CONCLUSIONS: Our findings support the notion that P300-marked SEs can help identify key nodes of transcriptional control during cell fate decisions.	ses	62-65	E1A binding protein p300	Homo sapiens	50-54
26150426-11	2015	SOX9 and SOX5/SOX6 thus cooperate genome-wide, primarily through SEs, to implement the growth plate chondrocyte differentiation program.	ses	65-68	SRY-box transcription factor 9	Rattus norvegicus	0-4
26150426-11	2015	SOX9 and SOX5/SOX6 thus cooperate genome-wide, primarily through SEs, to implement the growth plate chondrocyte differentiation program.	ses	65-68	SRY-box transcription factor 5	Rattus norvegicus	9-13
26150426-11	2015	SOX9 and SOX5/SOX6 thus cooperate genome-wide, primarily through SEs, to implement the growth plate chondrocyte differentiation program.	ses	65-68	SRY-box transcription factor 6	Rattus norvegicus	14-18
26233874-5	2015	Compared with the HF group, SES attenuated increases of lipemia and prevented insulin resistance (IR) (P = 0.001).	ses	28-31	insulin	Homo sapiens	78-85
26233874-7	2015	SES decreased inflammation, lowering tumor necrosis factor-alpha (P = 0.0006) and interleukin-6 levels (P = 0.0112), decreasing polymorphonuclear cells and preventing nuclear factor-kappaB activity (P = 0.0259).	ses	0-3	tumor necrosis factor	Homo sapiens	37-64
26233874-7	2015	SES decreased inflammation, lowering tumor necrosis factor-alpha (P = 0.0006) and interleukin-6 levels (P = 0.0112), decreasing polymorphonuclear cells and preventing nuclear factor-kappaB activity (P = 0.0259).	ses	0-3	interleukin 6	Homo sapiens	82-95
26233874-8	2015	SES corrected plasma level of monocyte chemoattractant protein-1 (P = 0.0380), which was increased by the HF diet.	ses	0-3	C-C motif chemokine ligand 2	Homo sapiens	30-64