PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31761329-5	2020	Interestingly, silencing NCK1-AS1 confined cell proliferation, induced apoptosis and suppressed migration and invasion as well as enhanced DDP sensitivity in OC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	139-142	NCK adaptor protein 1	Homo sapiens	25-29
1390271-1	1992	Changes in acetylcholinesterase activity in blood and some organs of rats after intoxication with sarin, soman, VX, and 2-dimethylaminoethyl-(dimethylamido)-phosphonofluoridate (GV), in doses of roughly 2 x LD50 given intramuscularly, were obtained from published data and by experiment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	120-176	acetylcholinesterase	Rattus norvegicus	11-31
32052927-4	2020	We demonstrated that lncRNA MST1P2 (lnc-MST1P2) expression was dramatically upregulated, whereas miR-133b expression was downregulated in DDP-resistant bladder cancer cell lines, SW 780/DDP and RT4/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	138-141	microRNA 133b	Homo sapiens	97-105
32052927-6	2020	Both lnc-MST1P2 silence and miR-133b overexpression could resensitize DDP-resistant bladder cancer cells to DDP treatment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	70-73	macrophage stimulating 1 pseudogene 2	Homo sapiens	9-15
32052927-6	2020	Both lnc-MST1P2 silence and miR-133b overexpression could resensitize DDP-resistant bladder cancer cells to DDP treatment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	70-73	microRNA 133b	Homo sapiens	28-36
32052927-6	2020	Both lnc-MST1P2 silence and miR-133b overexpression could resensitize DDP-resistant bladder cancer cells to DDP treatment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	108-111	macrophage stimulating 1 pseudogene 2	Homo sapiens	9-15
32052927-6	2020	Both lnc-MST1P2 silence and miR-133b overexpression could resensitize DDP-resistant bladder cancer cells to DDP treatment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	108-111	microRNA 133b	Homo sapiens	28-36
32052927-8	2020	Inc-MST1P2/miR-133b axis affected the resistance of bladder cancer cells to DDP via Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	macrophage stimulating 1 pseudogene 2	Homo sapiens	4-10
32052927-8	2020	Inc-MST1P2/miR-133b axis affected the resistance of bladder cancer cells to DDP via Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	microRNA 133b	Homo sapiens	11-19
32052927-8	2020	Inc-MST1P2/miR-133b axis affected the resistance of bladder cancer cells to DDP via Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	sirtuin 1	Homo sapiens	84-89
32052927-8	2020	Inc-MST1P2/miR-133b axis affected the resistance of bladder cancer cells to DDP via Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	tumor protein p53	Homo sapiens	90-93
32052927-9	2020	In conclusion, MST1P2 serves as a competing endogenous RNA for miR-133b to counteract miR-133b-induced suppression on Sirt1, therefore enhancing the resistance of bladder cancer cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	187-190	macrophage stimulating 1 pseudogene 2	Homo sapiens	15-21
32052927-9	2020	In conclusion, MST1P2 serves as a competing endogenous RNA for miR-133b to counteract miR-133b-induced suppression on Sirt1, therefore enhancing the resistance of bladder cancer cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	187-190	microRNA 133b	Homo sapiens	63-71
32052927-9	2020	In conclusion, MST1P2 serves as a competing endogenous RNA for miR-133b to counteract miR-133b-induced suppression on Sirt1, therefore enhancing the resistance of bladder cancer cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	187-190	microRNA 133b	Homo sapiens	86-94
32052927-10	2020	MST1P2/miR-133b axis affects the resistance of bladder cancer cells to DDP via downstream Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	71-74	macrophage stimulating 1 pseudogene 2	Homo sapiens	0-6
32052927-10	2020	MST1P2/miR-133b axis affects the resistance of bladder cancer cells to DDP via downstream Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	71-74	microRNA 133b	Homo sapiens	7-15
32052927-10	2020	MST1P2/miR-133b axis affects the resistance of bladder cancer cells to DDP via downstream Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	71-74	sirtuin 1	Homo sapiens	90-95
32052927-10	2020	MST1P2/miR-133b axis affects the resistance of bladder cancer cells to DDP via downstream Sirt1/p53 signaling.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	71-74	tumor protein p53	Homo sapiens	96-99
31875843-6	2020	Besides, the downregulation of UBE2C reversed the cisplatin resistance states of SKOV3/DDP and A2780/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	87-90	ubiquitin conjugating enzyme E2 C	Homo sapiens	31-36
8165432-1	1993	Changes of acetylcholinesterase activity in the blood and different organs of the rat following intoxication with sarin, soman, VX and 2-dimethylamino-ethyl-(dimethylamido)phosphonofluoridate (GV) in doses of approximately 2 x LD50 (i.m.)	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	135-191	acetylcholinesterase	Rattus norvegicus	11-31
32058824-8	2020	Additionally, we found interfering Beclin-1using Beclin-1-shRNA also enhanced the proliferation-inhibiting and apoptosis-inducing effects of DDP on gastric cancer cells by inhibiting phosphorylation of Akt.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	141-144	beclin 1	Homo sapiens	35-43
32058824-8	2020	Additionally, we found interfering Beclin-1using Beclin-1-shRNA also enhanced the proliferation-inhibiting and apoptosis-inducing effects of DDP on gastric cancer cells by inhibiting phosphorylation of Akt.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	141-144	beclin 1	Homo sapiens	49-57
32058824-8	2020	Additionally, we found interfering Beclin-1using Beclin-1-shRNA also enhanced the proliferation-inhibiting and apoptosis-inducing effects of DDP on gastric cancer cells by inhibiting phosphorylation of Akt.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	141-144	AKT serine/threonine kinase 1	Homo sapiens	202-205
31875843-6	2020	Besides, the downregulation of UBE2C reversed the cisplatin resistance states of SKOV3/DDP and A2780/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	ubiquitin conjugating enzyme E2 C	Homo sapiens	31-36
32016462-11	2020	In addition, treatment with propofol and DDP regulated FOXO1 and increased apoptosis of ovarian cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	41-44	forkhead box O1	Homo sapiens	55-60
31761329-5	2020	Interestingly, silencing NCK1-AS1 confined cell proliferation, induced apoptosis and suppressed migration and invasion as well as enhanced DDP sensitivity in OC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	139-142	prostaglandin D2 receptor	Homo sapiens	30-33
31761329-10	2020	Furthermore, NCK1 upregulation reversed the influences of NCK1-AS1 inhibition on the biological behaviors and DDP resistance of OC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	110-113	NCK adaptor protein 1	Homo sapiens	13-17
31761329-10	2020	Furthermore, NCK1 upregulation reversed the influences of NCK1-AS1 inhibition on the biological behaviors and DDP resistance of OC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	110-113	NCK adaptor protein 1	Homo sapiens	58-62
31761329-10	2020	Furthermore, NCK1 upregulation reversed the influences of NCK1-AS1 inhibition on the biological behaviors and DDP resistance of OC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	110-113	prostaglandin D2 receptor	Homo sapiens	63-66
31957179-4	2020	We found that FGFRL1 levels are significantly up-regulated in multidrug-resistant SCLC cells (H69AR and H446DDP) compared with the sensitive parental cells (H69 and H446).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	104-111	fibroblast growth factor receptor like 1	Homo sapiens	14-20
31957833-4	2020	Our study aimed to investigate the effects of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript 1 (KCNQ1OT1) on DDP resistance of tongue cancer and the underlying mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	120-123	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	75-105
31894841-8	2020	MiR-129-1-3p showed a low level of expression in DDP-resistant NSCLC tissues.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	49-52	microRNA 129-1	Homo sapiens	0-9
31894841-9	2020	Moreover, miR-129-1-3p overexpression impaired DDP resistance in H446/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	47-50	microRNA 129-1	Homo sapiens	10-19
31894841-9	2020	Moreover, miR-129-1-3p overexpression impaired DDP resistance in H446/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	70-73	microRNA 129-1	Homo sapiens	10-19
31894841-9	2020	Moreover, miR-129-1-3p overexpression impaired DDP resistance in H446/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	70-73	microRNA 129-1	Homo sapiens	10-19
31894841-11	2020	Especially, SOX4 overexpression offset the effects of NORAD silence on H446/DDP and A549/DDP cells resistance to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	SRY-box transcription factor 4	Homo sapiens	12-16
31894841-11	2020	Especially, SOX4 overexpression offset the effects of NORAD silence on H446/DDP and A549/DDP cells resistance to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	89-92	SRY-box transcription factor 4	Homo sapiens	12-16
31894841-11	2020	Especially, SOX4 overexpression offset the effects of NORAD silence on H446/DDP and A549/DDP cells resistance to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	89-92	SRY-box transcription factor 4	Homo sapiens	12-16
31894841-12	2020	NORAD knockdown resensitized H446/DDP and A549/DDP to DDP in NSCLC via targeting miR-129-1-3p/SOX4 axis, offering a brand-new target for NSCLC chemo-resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	47-50	SRY-box transcription factor 4	Homo sapiens	94-98
31894841-12	2020	NORAD knockdown resensitized H446/DDP and A549/DDP to DDP in NSCLC via targeting miR-129-1-3p/SOX4 axis, offering a brand-new target for NSCLC chemo-resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	47-50	SRY-box transcription factor 4	Homo sapiens	94-98
31892570-8	2020	Finally, the combined treatment of 3-MA or CQ with DDP further up-regulated DDP-induced caspase-3 activity in vitro and exhibited synergistic anti-tumor effects on mice.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	51-54	caspase 3	Mus musculus	88-97
31892570-8	2020	Finally, the combined treatment of 3-MA or CQ with DDP further up-regulated DDP-induced caspase-3 activity in vitro and exhibited synergistic anti-tumor effects on mice.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	76-79	caspase 3	Mus musculus	88-97
31707347-8	2020	Importantly, XJD and DDP exhibited synergy on regulation of PVT1, miR181a-5p, and SP1 expressions.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	21-24	Pvt1 oncogene	Homo sapiens	60-64
31702387-5	2020	Functionally, knockdown of UCA1 remarkably inhibited proliferation and sensitized retinoblastoma cells to multiple chemotherapy drugs, including vincristine (VCR), carboplatin (CBP), cisplatin (DDP), VP-16 (etoposide), and 5-fluorouracil (5-Fu).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	194-197	urothelial cancer associated 1	Homo sapiens	27-31
31957833-4	2020	Our study aimed to investigate the effects of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript 1 (KCNQ1OT1) on DDP resistance of tongue cancer and the underlying mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	120-123	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	107-115
31957833-13	2020	Animal experiment revealed the effect of KCNQ1OT1 on DDP resistance of tongue cancer cells in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	53-56	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	41-49
31957833-14	2020	RESULTS: KCNQ1OT1 was upregulated in DDP-resistant tongue cancer tissues and cells, and mainly expressed in cytoplasm.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	37-40	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	9-17
31957833-15	2020	Functionally, the knockdown of KCNQ1OT1 inhibited the survival rate, proliferation, migration, invasion, and EMT of the DDP-resistant tongue cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	120-123	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	31-39
31957833-15	2020	Functionally, the knockdown of KCNQ1OT1 inhibited the survival rate, proliferation, migration, invasion, and EMT of the DDP-resistant tongue cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	120-123	IL2 inducible T cell kinase	Homo sapiens	109-112
31957833-17	2020	Moreover, miR-124-3p targeted TRIM14 and the downregulation of TRIM14 reduced the DDP resistance of tongue cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	82-85	microRNA 124-3	Homo sapiens	10-20
31957833-17	2020	Moreover, miR-124-3p targeted TRIM14 and the downregulation of TRIM14 reduced the DDP resistance of tongue cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	82-85	tripartite motif containing 14	Homo sapiens	63-69
31957833-19	2020	Furthermore, KCNQ1OT1 knockdown reduced the DDP-resistant tumor growth and weight through the miR-124-3p/TRIM14 axis in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	44-47	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	13-21
31957833-19	2020	Furthermore, KCNQ1OT1 knockdown reduced the DDP-resistant tumor growth and weight through the miR-124-3p/TRIM14 axis in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	44-47	microRNA 124-3	Homo sapiens	94-104
31957833-19	2020	Furthermore, KCNQ1OT1 knockdown reduced the DDP-resistant tumor growth and weight through the miR-124-3p/TRIM14 axis in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	44-47	tripartite motif containing 14	Homo sapiens	105-111
31957833-20	2020	CONCLUSIONS: LncRNA KCNQ1OT1 promotes the DDP resistance of tongue cancer by sponging miR-124-3p to regulate TRIM14 expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	42-45	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	20-28
31957833-20	2020	CONCLUSIONS: LncRNA KCNQ1OT1 promotes the DDP resistance of tongue cancer by sponging miR-124-3p to regulate TRIM14 expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	42-45	microRNA 124-3	Homo sapiens	86-96
31957833-20	2020	CONCLUSIONS: LncRNA KCNQ1OT1 promotes the DDP resistance of tongue cancer by sponging miR-124-3p to regulate TRIM14 expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	42-45	tripartite motif containing 14	Homo sapiens	109-115
31686523-11	2020	Mechanically, SIX1 was identified as a downstream target for miR-186-5p and was highly expressed in A549/DDP and H1299/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	105-108	SIX homeobox 1	Homo sapiens	14-18
31853314-8	2020	In conclusion, the present preclinical results indicated that targeting miR-31-5p may enhance the efficacy of TAX- and DDP-mediated chemotherapy in TNBC.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	119-122	microRNA 31	Homo sapiens	72-78
31686523-11	2020	Mechanically, SIX1 was identified as a downstream target for miR-186-5p and was highly expressed in A549/DDP and H1299/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	119-122	SIX homeobox 1	Homo sapiens	14-18
31686523-12	2020	Similarly, SIX1 knockdown could also suppress DDP resistant NSCLC cell proliferation, migration and invasion, and promote apoptosis rate, which was reversed by miR-186-5p downregulation.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	46-49	SIX homeobox 1	Homo sapiens	11-15
31686523-14	2020	In conclusion, upregulation of miR-186-5p suppresses cisplatin resistance in DDP resistant NSCLC cells both in vitro and in vivo presumably by targeting SIX1.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	77-80	SIX homeobox 1	Homo sapiens	153-157
31799659-1	2019	OBJECTIVE: To explore the effect of micro-ribonucleic acid (miR)-187 on cisplatin (DDP) resistance of gastric cancer cells by regulating the transforming growth factor-beta (TGF-beta)/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	83-86	microRNA 187	Homo sapiens	36-68
31908475-3	2019	The present study aimed to explore whether lncRNA NCK-AS1 could affect the cisplatin (DDP) resistance in human osteosarcoma cell and the underlying molecular mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	86-89	NCK adaptor protein 1	Homo sapiens	50-53
31908475-3	2019	The present study aimed to explore whether lncRNA NCK-AS1 could affect the cisplatin (DDP) resistance in human osteosarcoma cell and the underlying molecular mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	86-89	prostaglandin D2 receptor	Homo sapiens	54-57
31908475-8	2019	Results: The results revealed that NCK1-AS1 was significantly upregulated in osteosarcoma cells, as well as in DDP-resistant osteosarcoma cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	111-114	NCK adaptor protein 1	Homo sapiens	35-39
31908475-8	2019	Results: The results revealed that NCK1-AS1 was significantly upregulated in osteosarcoma cells, as well as in DDP-resistant osteosarcoma cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	111-114	prostaglandin D2 receptor	Homo sapiens	40-43
31908475-9	2019	NCK1-AS1 silence inhibited the proliferation, migration and invasion of osteosarcoma cells, whereas enhanced the sensitivity of osteosarcoma cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	150-153	NCK adaptor protein 1	Homo sapiens	0-4
31908475-9	2019	NCK1-AS1 silence inhibited the proliferation, migration and invasion of osteosarcoma cells, whereas enhanced the sensitivity of osteosarcoma cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	150-153	prostaglandin D2 receptor	Homo sapiens	5-8
31908475-11	2019	Most importantly, miR-137 overexpression enhanced the sensitivity of osteosarcoma cells to DDP, and high expression of NCK1-AS1 reversed the influences of miR-137 overexpression on DDP-resistant cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	91-94	microRNA 137	Homo sapiens	18-25
31908475-11	2019	Most importantly, miR-137 overexpression enhanced the sensitivity of osteosarcoma cells to DDP, and high expression of NCK1-AS1 reversed the influences of miR-137 overexpression on DDP-resistant cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	181-184	NCK adaptor protein 1	Homo sapiens	119-123
31908475-11	2019	Most importantly, miR-137 overexpression enhanced the sensitivity of osteosarcoma cells to DDP, and high expression of NCK1-AS1 reversed the influences of miR-137 overexpression on DDP-resistant cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	181-184	prostaglandin D2 receptor	Homo sapiens	124-127
31908475-11	2019	Most importantly, miR-137 overexpression enhanced the sensitivity of osteosarcoma cells to DDP, and high expression of NCK1-AS1 reversed the influences of miR-137 overexpression on DDP-resistant cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	181-184	microRNA 137	Homo sapiens	155-162
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	50-53	NCK adaptor protein 1	Homo sapiens	22-26
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	50-53	prostaglandin D2 receptor	Homo sapiens	27-30
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	50-53	microRNA 137	Homo sapiens	102-109
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	158-161	NCK adaptor protein 1	Homo sapiens	22-26
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	158-161	prostaglandin D2 receptor	Homo sapiens	27-30
31908475-12	2019	Conclusion: In short, NCK1-AS1 knockdown enhanced DDP sensitivity of osteosarcoma cells by regulating miR-137, which may be a novel potential target for anti-DDP resistance in human osteosarcoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	158-161	microRNA 137	Homo sapiens	102-109
31722522-5	2019	The in vivo studies of double-tumor-bearing nude mice demonstrate that the tumor inhibitory rates (TIR) of GOx&Pt@FcNV against cisplatin-resistant A549/DDP are 8.1 times and 3.3 times higher than those of Pt and Pt@FcNV, respectively; they are also 8.6 times and 4.3 times higher than Pt and Pt@FcNV against adriamycin-resistant MCF-7/ADR, respectively.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	156-159	hydroxyacid oxidase 1, liver	Mus musculus	107-110
31818312-14	2019	Furthermore, the reduction of YAP m6A modification by METTL3 knockdown inhibits tumor growth and enhances sensitivity to DDP in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	121-124	Yes1 associated transcriptional regulator	Homo sapiens	30-33
31818312-14	2019	Furthermore, the reduction of YAP m6A modification by METTL3 knockdown inhibits tumor growth and enhances sensitivity to DDP in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	121-124	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	54-60
31827397-9	2019	Results: HNF1A-AS1 was upregulated in DDP-resistant cell line HeLa/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	38-41	HNF1A antisense RNA 1	Homo sapiens	9-18
31827397-9	2019	Results: HNF1A-AS1 was upregulated in DDP-resistant cell line HeLa/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	67-70	HNF1A antisense RNA 1	Homo sapiens	9-18
31827397-14	2019	Conclusion: Our study provides evidence that CC-secreted exosomes carrying HNF1A-AS1 as a ceRNA of miR-34b to promote the expression of TUFT1, thereby promoting the DDP resistance in CC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	165-168	HNF1A antisense RNA 1	Homo sapiens	75-84
31827397-14	2019	Conclusion: Our study provides evidence that CC-secreted exosomes carrying HNF1A-AS1 as a ceRNA of miR-34b to promote the expression of TUFT1, thereby promoting the DDP resistance in CC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	165-168	microRNA 34b	Homo sapiens	99-106
31827397-14	2019	Conclusion: Our study provides evidence that CC-secreted exosomes carrying HNF1A-AS1 as a ceRNA of miR-34b to promote the expression of TUFT1, thereby promoting the DDP resistance in CC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	165-168	tuftelin 1	Homo sapiens	136-141
31603446-4	2019	Our study also found that the cellular uptake of HSA-ICG-DDP NPs in tumor cells and CAFs can be enhanced by SPARC-mediated endocytosis.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	53-60	secreted protein acidic and cysteine rich	Homo sapiens	108-113
31603446-6	2019	Treatment with HSA-ICG-DDP NPs induced generation of reactive oxygen species (ROS) and cytotoxicity in SPARC-highly expressed tumor and CAFs.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	19-26	secreted protein acidic and cysteine rich	Homo sapiens	103-108
31709623-2	2019	In this study, we investigated the effect of miRNA-146b on EMT in cisplatin (DDP) resistant human lung adenocarcinoma cells and the corresponding mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	77-80	microRNA 146b	Homo sapiens	45-55
31709623-8	2019	Besides, miR-146b was lowly expressed in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	47-50	microRNA 146b	Homo sapiens	9-17
31709623-8	2019	Besides, miR-146b was lowly expressed in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	60-63	microRNA 146b	Homo sapiens	9-17
31709623-9	2019	More importantly, overexpressed miR-146b could specifically bind to PTP1B, thus inhibiting the EMT process and ultimately reducing CR in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	143-146	microRNA 146b	Homo sapiens	32-40
31709623-9	2019	More importantly, overexpressed miR-146b could specifically bind to PTP1B, thus inhibiting the EMT process and ultimately reducing CR in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	143-146	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	68-73
31709623-9	2019	More importantly, overexpressed miR-146b could specifically bind to PTP1B, thus inhibiting the EMT process and ultimately reducing CR in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	156-159	microRNA 146b	Homo sapiens	32-40
31709623-9	2019	More importantly, overexpressed miR-146b could specifically bind to PTP1B, thus inhibiting the EMT process and ultimately reducing CR in H1299/DDP and A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	156-159	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	68-73
31709623-10	2019	Finally, overexpressed miR-146b observably inhibited tumor growth in xenograft model mice and inhibited the EMT phenotype of A549/DDP cells in vivo by regulating the expressions of EMT-related proteins.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	130-133	microRNA 146b	Mus musculus	23-31
31799659-7	2019	RESULTS: MiR-187 level had a negative correlation with DDP-resistance of GES-1, SGC7901, and SGC7901/DDP cells, and among them, the GES-1 cells had the lowest DDP-resistance and the highest expression of miR-187.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	microRNA 187	Homo sapiens	9-16
31799659-7	2019	RESULTS: MiR-187 level had a negative correlation with DDP-resistance of GES-1, SGC7901, and SGC7901/DDP cells, and among them, the GES-1 cells had the lowest DDP-resistance and the highest expression of miR-187.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	microRNA 187	Homo sapiens	9-16
31799659-8	2019	CCK-8 assay revealed that compared with that in the control group, DDP-resistance significantly declined in the miR-187 mimic group, while it was significantly enhanced in miR-187 inhibitor group (p<0.01).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	67-70	microRNA 187	Homo sapiens	112-119
31799659-9	2019	According to the results of flow cytometry, after treatment with 100 nM DDP for 12 h, the apoptotic rate in miR-187 mimic group enhanced, while it was markedly reduced in the miR-187 inhibitor group (p<0.01).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	72-75	microRNA 187	Homo sapiens	108-115
31799659-9	2019	According to the results of flow cytometry, after treatment with 100 nM DDP for 12 h, the apoptotic rate in miR-187 mimic group enhanced, while it was markedly reduced in the miR-187 inhibitor group (p<0.01).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	72-75	microRNA 187	Homo sapiens	175-182
31799659-12	2019	CONCLUSIONS: The overexpression of miR-187 alleviates DDP-resistance in gastric cancer cells by inhibiting the TGF-beta/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	54-57	microRNA 187	Homo sapiens	35-42
31799659-12	2019	CONCLUSIONS: The overexpression of miR-187 alleviates DDP-resistance in gastric cancer cells by inhibiting the TGF-beta/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	54-57	transforming growth factor beta 1	Homo sapiens	111-119
31799659-12	2019	CONCLUSIONS: The overexpression of miR-187 alleviates DDP-resistance in gastric cancer cells by inhibiting the TGF-beta/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	54-57	SMAD family member 4	Homo sapiens	120-124
31612051-0	2019	Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	62-65	cellular inhibitor of PP2A	Homo sapiens	143-148
31612051-0	2019	Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	62-65	AKT serine/threonine kinase 1	Homo sapiens	149-152
31612051-0	2019	Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	62-65	mechanistic target of rapamycin kinase	Homo sapiens	153-157
31612051-5	2019	CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	124-127	cellular inhibitor of PP2A	Homo sapiens	0-5
31612051-5	2019	CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	124-127	protein tyrosine kinase 2 beta	Homo sapiens	25-41
31612051-5	2019	CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	124-127	AKT serine/threonine kinase 1	Homo sapiens	43-46
31612051-5	2019	CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	124-127	mechanistic target of rapamycin kinase	Homo sapiens	48-77
31612051-5	2019	CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	124-127	mechanistic target of rapamycin kinase	Homo sapiens	79-83
31612051-9	2019	When assessing the underlying molecular mechanism, it was revealed that PPI and PPVII enhanced DDP-induced apoptosis in A549/DDP cells via p53 upregulation and the caspase-dependent pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	95-98	tumor protein p53	Homo sapiens	139-142
31612051-10	2019	Furthermore, PPI and PPVII reversed the EMT and suppressed CIP2A and its downstream AKT/mTOR signaling cascade in A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	119-122	cellular inhibitor of PP2A	Homo sapiens	59-64
31612051-10	2019	Furthermore, PPI and PPVII reversed the EMT and suppressed CIP2A and its downstream AKT/mTOR signaling cascade in A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	119-122	AKT serine/threonine kinase 1	Homo sapiens	84-87
31612051-10	2019	Furthermore, PPI and PPVII reversed the EMT and suppressed CIP2A and its downstream AKT/mTOR signaling cascade in A549/DDP cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	119-122	mechanistic target of rapamycin kinase	Homo sapiens	88-92
31579066-2	2019	The aim of the present study was to determine whether MDIG is involved in cisplatin (DDP) resistance in lung adenocarcinoma, and to investigate the associated molecular mechanism.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	85-88	ribosomal oxygenase 2	Homo sapiens	54-58
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	81-84	ribosomal oxygenase 2	Homo sapiens	68-72
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	81-84	ribosomal oxygenase 2	Homo sapiens	194-198
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	252-255	ribosomal oxygenase 2	Homo sapiens	68-72
31579066-4	2019	The results revealed that the mRNA and protein expression levels of MDIG in A549/DDP cells were significantly higher compared with those in A549 cells, and that the protein expression levels of MDIG increased in a dose-dependent manner with increasing DDP concentrations.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	252-255	ribosomal oxygenase 2	Homo sapiens	194-198
31579066-5	2019	Overexpression of MDIG in A549 and A549/DDP cells led to an increase in the IC50 value, whereas silencing of MDIG led to a clear reduction in the IC50 value.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	40-43	ribosomal oxygenase 2	Homo sapiens	18-22
31579066-6	2019	The overexpression of MDIG in the A549 and A549/DDP cells markedly upregulated the mRNA and protein expression levels of ABCB1, ABCC1, ABCG2, WNT family member 5A, WNT family member 3A and active beta-catenin, and these were markedly decreased following MDIG silencing.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	48-51	ribosomal oxygenase 2	Homo sapiens	22-26
31579066-6	2019	The overexpression of MDIG in the A549 and A549/DDP cells markedly upregulated the mRNA and protein expression levels of ABCB1, ABCC1, ABCG2, WNT family member 5A, WNT family member 3A and active beta-catenin, and these were markedly decreased following MDIG silencing.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	48-51	ATP binding cassette subfamily B member 1	Homo sapiens	121-126
31579066-6	2019	The overexpression of MDIG in the A549 and A549/DDP cells markedly upregulated the mRNA and protein expression levels of ABCB1, ABCC1, ABCG2, WNT family member 5A, WNT family member 3A and active beta-catenin, and these were markedly decreased following MDIG silencing.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	48-51	ATP binding cassette subfamily C member 1	Homo sapiens	128-133
31579066-6	2019	The overexpression of MDIG in the A549 and A549/DDP cells markedly upregulated the mRNA and protein expression levels of ABCB1, ABCC1, ABCG2, WNT family member 5A, WNT family member 3A and active beta-catenin, and these were markedly decreased following MDIG silencing.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	48-51	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	135-140
31579066-7	2019	Taken together, these results demonstrated that the DDP resistance of lung adenocarcinoma may be associated with an upregulation of MDIG expression, and that the expression levels of MDIG are positively associated with the degree of DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	52-55	ribosomal oxygenase 2	Homo sapiens	132-136
31579066-7	2019	Taken together, these results demonstrated that the DDP resistance of lung adenocarcinoma may be associated with an upregulation of MDIG expression, and that the expression levels of MDIG are positively associated with the degree of DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	233-236	ribosomal oxygenase 2	Homo sapiens	183-187
31579066-8	2019	Furthermore, MDIG promoted the expression of ABC transporters in tumor cells by activating the WNT/beta-catenin signaling pathway, which may, in turn, lead to DDP resistance in lung adenocarcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	159-162	ribosomal oxygenase 2	Homo sapiens	13-17
31579066-8	2019	Furthermore, MDIG promoted the expression of ABC transporters in tumor cells by activating the WNT/beta-catenin signaling pathway, which may, in turn, lead to DDP resistance in lung adenocarcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	159-162	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	45-48
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	56-59	microRNA 145a	Mus musculus	18-25
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	56-59	thymoma viral proto-oncogene 3	Mus musculus	42-46
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	56-59	thymoma viral proto-oncogene 3	Mus musculus	165-169
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	128-131	microRNA 145a	Mus musculus	18-25
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	128-131	thymoma viral proto-oncogene 3	Mus musculus	42-46
31582906-10	2019	Overexpression of miR-145 or knockdown of AKT3 promoted DDP-induced cell cycle arrest and apoptosis, as well as reduced IC50 of DDP treatment, which was reversed by AKT3 overexpression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	128-131	thymoma viral proto-oncogene 3	Mus musculus	165-169
31582906-12	2019	Furthermore, overexpression of miR-145 enhanced the DDP-induced tumor growth suppression in vivo.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	52-55	microRNA 145a	Mus musculus	31-38
31582906-13	2019	Conclusion: miR-145 increased the sensitivity of ESCC to DDP, and facilitated DDP-induced apoptosis, cycle arrest by directly inhibiting PI3K/AKT signaling pathway to decrease multidrug resistance-associated proteins MRP1 and P-gp expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	57-60	microRNA 145a	Mus musculus	12-19
31582906-13	2019	Conclusion: miR-145 increased the sensitivity of ESCC to DDP, and facilitated DDP-induced apoptosis, cycle arrest by directly inhibiting PI3K/AKT signaling pathway to decrease multidrug resistance-associated proteins MRP1 and P-gp expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	78-81	microRNA 145a	Mus musculus	12-19
31582906-13	2019	Conclusion: miR-145 increased the sensitivity of ESCC to DDP, and facilitated DDP-induced apoptosis, cycle arrest by directly inhibiting PI3K/AKT signaling pathway to decrease multidrug resistance-associated proteins MRP1 and P-gp expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	78-81	thymoma viral proto-oncogene 3	Mus musculus	142-145
31582906-13	2019	Conclusion: miR-145 increased the sensitivity of ESCC to DDP, and facilitated DDP-induced apoptosis, cycle arrest by directly inhibiting PI3K/AKT signaling pathway to decrease multidrug resistance-associated proteins MRP1 and P-gp expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	78-81	prolactin family 2, subfamily c, member 2	Mus musculus	217-221
31582906-13	2019	Conclusion: miR-145 increased the sensitivity of ESCC to DDP, and facilitated DDP-induced apoptosis, cycle arrest by directly inhibiting PI3K/AKT signaling pathway to decrease multidrug resistance-associated proteins MRP1 and P-gp expression.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	78-81	phosphoglycolate phosphatase	Mus musculus	226-230
31582906-14	2019	Improving the efficacy of DDP by boosting the miR-145 level provides a new strategy for treatment of ESCC.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	26-29	microRNA 145a	Mus musculus	46-53
31551012-3	2019	In this study, we aimed to investigate the functional role and the underlying molecular mechanisms of lncRNA HOXD cluster antisense RNA 1 (HOXD-AS1) in cisplatin (DDP) resistance in gastric cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	163-166	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	109-137
31551012-3	2019	In this study, we aimed to investigate the functional role and the underlying molecular mechanisms of lncRNA HOXD cluster antisense RNA 1 (HOXD-AS1) in cisplatin (DDP) resistance in gastric cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	163-166	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	139-147
31551012-4	2019	Our results revealed that HOXD-AS1 was upregulated in DDP-resistant gastric cancer tissues and cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	54-57	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	26-34
31551012-6	2019	Knockdown of HOXD-AS1 facilitated the sensitivity of DDP-resistant gastric cancer cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	53-56	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	13-21
31551012-6	2019	Knockdown of HOXD-AS1 facilitated the sensitivity of DDP-resistant gastric cancer cells to DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	91-94	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	13-21
31551012-8	2019	More importantly, PDCD4 silencing counteracted HOXD-AS1 knockdown-mediated enhancement of DDP sensitivity in DDP-resistant gastric cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	90-93	programmed cell death 4	Homo sapiens	18-23
31551012-8	2019	More importantly, PDCD4 silencing counteracted HOXD-AS1 knockdown-mediated enhancement of DDP sensitivity in DDP-resistant gastric cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	90-93	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	47-55
31551012-8	2019	More importantly, PDCD4 silencing counteracted HOXD-AS1 knockdown-mediated enhancement of DDP sensitivity in DDP-resistant gastric cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	109-112	programmed cell death 4	Homo sapiens	18-23
31551012-8	2019	More importantly, PDCD4 silencing counteracted HOXD-AS1 knockdown-mediated enhancement of DDP sensitivity in DDP-resistant gastric cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	109-112	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	47-55
31551012-9	2019	In summary, HOXD-AS1 led to DDP resistance in gastric cancer by epigenetically suppressing PDCD4 expression, providing a novel therapeutic strategy for patients with gastric cancer with chemoresistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	28-31	HOXD antisense growth-associated long non-coding RNA	Homo sapiens	12-20
31551012-9	2019	In summary, HOXD-AS1 led to DDP resistance in gastric cancer by epigenetically suppressing PDCD4 expression, providing a novel therapeutic strategy for patients with gastric cancer with chemoresistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	28-31	programmed cell death 4	Homo sapiens	91-96
31885310-3	2020	This study aims to identify the effect of miR-29c-3p/FOXP1/ATG14 pathway in regulating autophagy and DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	forkhead box P1	Homo sapiens	53-58
31885310-3	2020	This study aims to identify the effect of miR-29c-3p/FOXP1/ATG14 pathway in regulating autophagy and DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	autophagy related 14	Homo sapiens	59-64
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	92-95	forkhead box P1	Homo sapiens	31-36
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	92-95	autophagy related 14	Homo sapiens	38-43
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	154-157	forkhead box P1	Homo sapiens	31-36
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	154-157	autophagy related 14	Homo sapiens	38-43
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	154-157	forkhead box P1	Homo sapiens	31-36
31885310-4	2020	The expressions of miR-29c-3p, FOXP1, ATG14 and autophagy-related proteins were detected in DDP-sensitive ovarian cancer cell lines (SKOV3 and A2780) and DDP-resistant cell lines (SKOV3/DDP and A2780/DDP).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	154-157	autophagy related 14	Homo sapiens	38-43
31885310-9	2020	Overexpression of miR-29c-3p increased DDP sensitivity by downregulating FOXP1/ATG14 in vitro.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	39-42	forkhead box P1	Homo sapiens	73-78
31885310-9	2020	Overexpression of miR-29c-3p increased DDP sensitivity by downregulating FOXP1/ATG14 in vitro.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	39-42	autophagy related 14	Homo sapiens	79-84
31885310-11	2020	Overexpression of miR-29c-3p inhibited autophagy and DDP resistance partly via downregulating FOXP1/ATG14 pathway, suggesting miR-29c-3p as a novel target in overcoming DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	53-56	forkhead box P1	Homo sapiens	94-99
31885310-11	2020	Overexpression of miR-29c-3p inhibited autophagy and DDP resistance partly via downregulating FOXP1/ATG14 pathway, suggesting miR-29c-3p as a novel target in overcoming DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	53-56	autophagy related 14	Homo sapiens	100-105
31885310-11	2020	Overexpression of miR-29c-3p inhibited autophagy and DDP resistance partly via downregulating FOXP1/ATG14 pathway, suggesting miR-29c-3p as a novel target in overcoming DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	169-172	forkhead box P1	Homo sapiens	94-99
31885310-11	2020	Overexpression of miR-29c-3p inhibited autophagy and DDP resistance partly via downregulating FOXP1/ATG14 pathway, suggesting miR-29c-3p as a novel target in overcoming DDP resistance in ovarian cancer.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	169-172	autophagy related 14	Homo sapiens	100-105
31653849-5	2019	However, we observe that YTHDF1 high expression correlates with better clinical outcome, with its depletion rendering cancerous cells resistant to cisplatin (DDP) treatment.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	158-161	YTH N6-methyladenosine RNA binding protein 1	Homo sapiens	25-31
31696470-0	2019	MiR-203 regulates DJ-1 expression and affects proliferation, apoptosis and DDP resistance of pancreatic cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	75-78	microRNA 203a	Homo sapiens	0-7
31696470-6	2019	The DDP-resistant cell line SW1990/DDP was established and divided into miR-NC group and miR-203 mimic group followed by analysis of the expression of DJ-1, PTEN and p-AKT, cell apoptosis, and proliferation.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	4-7	membrane associated ring-CH-type finger 8	Homo sapiens	72-75
31696470-8	2019	The expression of miR-203 in SW1990/DDP cells was significantly lower than that in SW1990 cells, while the expression of DJ-1 mRNA and protein was significantly higher than that in SW1990 cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	36-39	microRNA 203a	Homo sapiens	18-25
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	79-82	Parkinsonism associated deglycase	Homo sapiens	46-50
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	79-82	microRNA 203a	Homo sapiens	120-127
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	79-82	phosphatase and tensin homolog	Homo sapiens	178-182
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	294-297	Parkinsonism associated deglycase	Homo sapiens	46-50
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	294-297	microRNA 203a	Homo sapiens	120-127
31696470-9	2019	Compared with miR-NC group, the expression of DJ-1 and p-AKT protein in SW1990/DDP cells was significantly decreased in miR-203 mimic transfection group, while the expression of PTEN was significantly increased with increased cell apoptosis and decreased cell proliferation, as well as reduced DDP resistance.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	294-297	phosphatase and tensin homolog	Homo sapiens	178-182
31696470-11	2019	Elevated miR-203 can inhibit the expression of DJ-1, affect the activity of PTEN-PI3K/AKT pathway, inhibit the proliferation of pancreatic cancer cells, induce cell apoptosis, and reduce DDP resistance of pancreatic cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	187-190	microRNA 203a	Homo sapiens	9-16
31696470-11	2019	Elevated miR-203 can inhibit the expression of DJ-1, affect the activity of PTEN-PI3K/AKT pathway, inhibit the proliferation of pancreatic cancer cells, induce cell apoptosis, and reduce DDP resistance of pancreatic cancer cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	187-190	Parkinsonism associated deglycase	Homo sapiens	47-51
31579424-7	2019	Hypermethylation and low expression of RASSF1A gene were detected in PEOC and A2780/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	84-87	Ras association domain family member 1	Homo sapiens	39-46
31579424-8	2019	Subsequent to being exposed to different concentrations of zebularine-stimulated A2780/DDP, the RASSF1A methylation level was decreased, while the unmethylation level was increased.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	87-90	Ras association domain family member 1	Homo sapiens	96-103
31799659-1	2019	OBJECTIVE: To explore the effect of micro-ribonucleic acid (miR)-187 on cisplatin (DDP) resistance of gastric cancer cells by regulating the transforming growth factor-beta (TGF-beta)/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	83-86	transforming growth factor beta 1	Homo sapiens	141-172
31799659-1	2019	OBJECTIVE: To explore the effect of micro-ribonucleic acid (miR)-187 on cisplatin (DDP) resistance of gastric cancer cells by regulating the transforming growth factor-beta (TGF-beta)/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	83-86	transforming growth factor beta 1	Homo sapiens	174-182
31799659-1	2019	OBJECTIVE: To explore the effect of micro-ribonucleic acid (miR)-187 on cisplatin (DDP) resistance of gastric cancer cells by regulating the transforming growth factor-beta (TGF-beta)/Smad signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	83-86	SMAD family member 4	Homo sapiens	184-188
31799659-7	2019	RESULTS: MiR-187 level had a negative correlation with DDP-resistance of GES-1, SGC7901, and SGC7901/DDP cells, and among them, the GES-1 cells had the lowest DDP-resistance and the highest expression of miR-187.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	55-58	microRNA 187	Homo sapiens	9-16
31934068-18	2019	Tumor apoptosis and the rat survival rate in the AEC + DDP group were further enhanced, as demonstrated by CD31 (or alpha-SMA) IF and GFP colocalization, as well as GFP western blot.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	55-58	platelet and endothelial cell adhesion molecule 1	Rattus norvegicus	107-111
31555430-2	2019	In diabetic use, the DPP-4 inhibitor can block the DDP-4 to attenuate GLP-1 degradation and prolong GLP-1 its action and sensitize insulin activity for the purpose of lowering blood glucose.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	51-54	dipeptidyl peptidase 4	Homo sapiens	21-26
31555430-2	2019	In diabetic use, the DPP-4 inhibitor can block the DDP-4 to attenuate GLP-1 degradation and prolong GLP-1 its action and sensitize insulin activity for the purpose of lowering blood glucose.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	51-54	glucagon	Homo sapiens	70-75
31646806-10	2019	The VEGF and MMP-2 levels in both DTX+DDP and TAX+DDP group were decreased compared with those before treatment (183.35+-25.26 vs. 279.18+-27.75 pg/mL and 228.22+-40.21 vs. 316.11+-33.6 pg/mL (p<0.05).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	38-41	vascular endothelial growth factor A	Homo sapiens	4-8
31646806-10	2019	The VEGF and MMP-2 levels in both DTX+DDP and TAX+DDP group were decreased compared with those before treatment (183.35+-25.26 vs. 279.18+-27.75 pg/mL and 228.22+-40.21 vs. 316.11+-33.6 pg/mL (p<0.05).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	38-41	matrix metallopeptidase 2	Homo sapiens	13-18
31646806-10	2019	The VEGF and MMP-2 levels in both DTX+DDP and TAX+DDP group were decreased compared with those before treatment (183.35+-25.26 vs. 279.18+-27.75 pg/mL and 228.22+-40.21 vs. 316.11+-33.6 pg/mL (p<0.05).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	50-53	vascular endothelial growth factor A	Homo sapiens	4-8
31646806-10	2019	The VEGF and MMP-2 levels in both DTX+DDP and TAX+DDP group were decreased compared with those before treatment (183.35+-25.26 vs. 279.18+-27.75 pg/mL and 228.22+-40.21 vs. 316.11+-33.6 pg/mL (p<0.05).	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	50-53	matrix metallopeptidase 2	Homo sapiens	13-18
31646806-14	2019	However, DTX+DDP is more efficacious in lowering indicators such as serum CA125, HE4 and MMP-2 and ROMA index and adverse reactions, thus providing a more efficient practice scheme with lower toxic side effects for the clinical treatment of ovarian carcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	13-16	mucin 16, cell surface associated	Homo sapiens	74-79
31646806-14	2019	However, DTX+DDP is more efficacious in lowering indicators such as serum CA125, HE4 and MMP-2 and ROMA index and adverse reactions, thus providing a more efficient practice scheme with lower toxic side effects for the clinical treatment of ovarian carcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	13-16	WAP four-disulfide core domain 2	Homo sapiens	81-84
31646806-14	2019	However, DTX+DDP is more efficacious in lowering indicators such as serum CA125, HE4 and MMP-2 and ROMA index and adverse reactions, thus providing a more efficient practice scheme with lower toxic side effects for the clinical treatment of ovarian carcinoma.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	13-16	matrix metallopeptidase 2	Homo sapiens	89-94
31661694-1	2019	OBJECTIVE: To investigate whether TRIAP1inhibition affects the ovarian cancer cell resistance to cisplatin (DDP) via the Cyt c/Apaf-1/caspase-9 pathway by in vitro and in vivo experiments.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	108-111	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	34-40
31661694-2	2019	METHODS: CCK8 assay was performed to find out how treatment with both TRIAP1 siRNA and DDP affects the cell viability of SKOV3 cells and DDP-resistant human ovarian carcinoma cell line SKOV3/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	137-140	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	70-76
31661694-2	2019	METHODS: CCK8 assay was performed to find out how treatment with both TRIAP1 siRNA and DDP affects the cell viability of SKOV3 cells and DDP-resistant human ovarian carcinoma cell line SKOV3/DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	137-140	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	70-76
31661694-8	2019	The proliferation rate was lower in SKOV3/DDP cells transfected with TRIAP1 siRNA combined with treatment of DDP (1, 2, 4, 6, 8, 16, 32 mug/mL) than in those transfected with control siRNA.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	42-45	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	69-75
31661694-8	2019	The proliferation rate was lower in SKOV3/DDP cells transfected with TRIAP1 siRNA combined with treatment of DDP (1, 2, 4, 6, 8, 16, 32 mug/mL) than in those transfected with control siRNA.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	42-45	translocase of inner mitochondrial membrane 8A	Homo sapiens	109-131
31661694-9	2019	Moreover, the TRIAP1 siRNA group had an increased SKOV3/DDP cell apoptosis rate with the activation of the Cyt c/Apaf-1/caspase-9 pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	56-59	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	14-20
31661694-10	2019	During DDP treatment, nude mice in TRIAP1 siRNA group had slower growth and smaller size of transplanted tumor than those in control siRNA group, with increased expression of Cyt c, Apaf-1, and caspase-9.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	7-10	TP53 regulated inhibitor of apoptosis 1	Mus musculus	35-41
31661694-11	2019	CONCLUSION: TRIAP1 inhibition may enhance the sensitivity of SKOV3/DDP cells to cisplatin via activation of the Cyt c/Apaf-1/caspase-9 pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	67-70	TP53 regulated inhibitor of apoptosis 1	Homo sapiens	12-18
31661694-11	2019	CONCLUSION: TRIAP1 inhibition may enhance the sensitivity of SKOV3/DDP cells to cisplatin via activation of the Cyt c/Apaf-1/caspase-9 pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	67-70	apoptotic peptidase activating factor 1	Homo sapiens	118-124
31661694-11	2019	CONCLUSION: TRIAP1 inhibition may enhance the sensitivity of SKOV3/DDP cells to cisplatin via activation of the Cyt c/Apaf-1/caspase-9 pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	67-70	caspase 9	Homo sapiens	125-134
31938149-4	2018	However, the role of Sall4 on drug resistance of lung cancer cells and the mechanism by which Sall4 regulates the sensitivity of lung cancer cells to cisplatin (DDP) remains unknown.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	161-164	spalt like transcription factor 4	Homo sapiens	94-99
31966505-7	2017	Bcl-2-associated X protein (Bax) expression was promoted and B-cell lymphoma-2 (Bcl-2) expression was suppressed, In addition, Notch1, Notch1 intracellular domain (NICD1) and hairy and enhancer of split 1 (Hes-1) were decreased dramatically in HT29 cells treated with Cur combined with DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	286-289	BCL2 associated X, apoptosis regulator	Homo sapiens	0-26
31966505-7	2017	Bcl-2-associated X protein (Bax) expression was promoted and B-cell lymphoma-2 (Bcl-2) expression was suppressed, In addition, Notch1, Notch1 intracellular domain (NICD1) and hairy and enhancer of split 1 (Hes-1) were decreased dramatically in HT29 cells treated with Cur combined with DDP.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	286-289	BCL2 apoptosis regulator	Homo sapiens	0-5
31966505-9	2017	It showed that DDP combined with Cur promote the apoptosis of HT29 cells via regulating the expression of related apoptotic genes and inhibiting the activation of Notch1 signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	15-18	notch receptor 1	Homo sapiens	163-169
31966510-6	2017	The expression of miR-146a in DDP-resistant NSCLC tumor samples was significantly lower than that in DDP-sensitive ones.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	30-33	microRNA 146a	Homo sapiens	18-26
31966510-6	2017	The expression of miR-146a in DDP-resistant NSCLC tumor samples was significantly lower than that in DDP-sensitive ones.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	101-104	microRNA 146a	Homo sapiens	18-26
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	TNF receptor associated factor 6	Homo sapiens	22-27
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	interleukin 1 receptor associated kinase 1	Homo sapiens	29-34
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	nuclear factor kappa B subunit 1	Homo sapiens	39-42
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	RELA proto-oncogene, NF-kB subunit	Homo sapiens	145-148
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	84-87	TNF receptor associated factor 6	Homo sapiens	22-27
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	84-87	interleukin 1 receptor associated kinase 1	Homo sapiens	29-34
31966510-8	2017	The protein levels of TRAF6, IRAK1 and p50 were up-regulated in A549/DDP and Calu-1/DDP cells compared to parental cells, and phosphorylation of p65 was also increased, indicating the activation of NF-kappaB signaling pathway.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	84-87	nuclear factor kappa B subunit 1	Homo sapiens	39-42
31966510-11	2017	In conclusion, the study indicates that miR-146a regulates the DDP sensitivity by inhibiting NF-kappaB signaling pathway in NSCLC cells.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	63-66	microRNA 146a	Homo sapiens	40-48
31966418-3	2017	This study aims to investigate the effect of TGF-beta1 on cisplatin (DDP) inhibiting the proliferation, migration and invasion of breast cancer and its correlation with EMT.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	transforming growth factor beta 1	Homo sapiens	45-54
31966418-3	2017	This study aims to investigate the effect of TGF-beta1 on cisplatin (DDP) inhibiting the proliferation, migration and invasion of breast cancer and its correlation with EMT.	2-dimethylaminoethyl(dimethylamido)phosphonofluoridate	69-72	IL2 inducible T cell kinase	Homo sapiens	169-172