PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2565158-6	1989	Inhibition of thiazide stimulated renin release by bevantolol may contribute to the antihypertensive effect of the combined therapy.	bevantolol	51-61	renin	Homo sapiens	34-39
17628611-6	2007	The mRNA levels of beta(1)- and beta(2)-adrenoceptors were not altered by propranolol treatment, while beta(1)-adrenoceptor mRNA significantly decreased after administration of atenolol or bevantolol without changing the level of beta(2)-adrenoceptor mRNA.	bevantolol	189-199	adrenoceptor beta 1	Rattus norvegicus	103-123
1354761-3	1992	The affinity of bevantolol to beta 1-adrenoceptor was equal to that of propranolol.	bevantolol	16-26	adrenoceptor beta 1	Rattus norvegicus	30-49
1354761-5	1992	These results suggest that bevantolol is a beta 1-adrenoceptor antagonist with a relatively high affinity to alpha 1-adrenoceptor subtypes.	bevantolol	27-37	adrenoceptor beta 1	Rattus norvegicus	43-62
2565158-0	1989	Bevantolol attenuates thiazide stimulated renin secretion and catecholamine release in diuretic resistant hypertensives.	bevantolol	0-10	renin	Homo sapiens	42-47
2563955-2	1989	The objective was to determine to what extent decreased circulation levels of catecholamines and renin activity contributed to the hypotensive action of bevantolol and whether it demonstrated a significant sparing effect on vascular resistance.	bevantolol	153-163	renin	Homo sapiens	97-102
2878595-1	1986	The antihypertensive efficacy of bevantolol, a selective beta 1-adrenoreceptor antagonist, was evaluated in 17 patients with essential hypertension, using continuous ambulatory intraarterial blood pressure (BP) monitoring.	bevantolol	33-43	adrenoceptor beta 1	Homo sapiens	57-78
2888789-0	1987	Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions.	bevantolol	0-10	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	14-20
2888789-1	1987	UNLABELLED: Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.	bevantolol	12-22	adrenoceptor beta 1	Homo sapiens	28-47
6148733-0	1984	Selectivity of bevantolol hydrochloride, a beta 1-adrenoceptor antagonist, in asthmatic patients.	bevantolol	15-39	adrenoceptor beta 1	Homo sapiens	43-62
2858236-0	1985	Cardiovascular effects of bevantolol, a selective beta 1-adrenoceptor antagonist with a novel pharmacological profile.	bevantolol	26-36	adrenoceptor beta 1	Rattus norvegicus	50-69
6148733-10	1984	Thus bevantolol has relative beta 1-adrenoceptor antagonist selectivity.	bevantolol	5-15	adrenoceptor beta 1	Homo sapiens	29-48
24788554-3	2014	The aim of our study was to determine the potency of 14 compounds chemically related to bupranolol or bevantolol and two xanthone derivatives at the low-affinity site of the beta1-adrenoceptor.	bevantolol	102-112	adrenoceptor beta 1	Rattus norvegicus	174-192