PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11283230-9	2001	In conclusion, somatostatin can inhibit glucose-induced electrical activity in MIN-6 cells by the combined activation of K-ATP and GIRK channels.	k-atp	121-126	somatostatin	Mus musculus	15-27
9238070-9	1997	We used a truncated form of Kir6.2, which expresses independently of SUR1, to show that GTP blocks K-ATP currents by interaction with Kir6.2 and that the potentiatory effects of GTP are endowed by SUR1.	k-atp	99-104	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	28-34
9238070-9	1997	We used a truncated form of Kir6.2, which expresses independently of SUR1, to show that GTP blocks K-ATP currents by interaction with Kir6.2 and that the potentiatory effects of GTP are endowed by SUR1.	k-atp	99-104	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	134-140
9238070-10	1997	We also showed that mutation of the lysine residue in the Walker A motif of either the first (K719A) or second (K1384M) nucleotide-binding domain of SUR1 abolished both the potentiatory effects of GTP and GDP on K-ATP currents and their ability to support stimulation by diazoxide.	k-atp	212-217	ATP binding cassette subfamily C member 8	Homo sapiens	149-153
9041442-15	1997	K-ATP and ATP gamma S were as efficient as Mg-ATP in sustaining NHE-1 activity, while AMP-PNP and AMP-PCP only partially substituted for ATP.	k-atp	0-5	sodium/hydrogen exchanger 1	Cricetulus griseus	64-69
35588738-0	2022	KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling.	k-atp	23-28	potassium inwardly-rectifying channel, subfamily J, member 8	Mus musculus	0-5
34626854-11	2021	Conversely, GLP-1Ra"s decreased excitatory input to and indirectly inhibited NPY/AgRP neurons through activation of K-ATP and TRPC5 channels in GABAergic neurons.	k-atp	116-121	neuropeptide Y	Mus musculus	77-80
34626854-11	2021	Conversely, GLP-1Ra"s decreased excitatory input to and indirectly inhibited NPY/AgRP neurons through activation of K-ATP and TRPC5 channels in GABAergic neurons.	k-atp	116-121	agouti related neuropeptide	Mus musculus	81-85
35588738-0	2022	KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling.	k-atp	23-28	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	Mus musculus	6-11
27908292-14	2016	CONCLUSIONS: In K-ATP CHI patients managed by medical treatment only, severity is reduced over time in the majority, including those with compound heterozygous and homozygous mutations in ABCC8/KCNJ11.	k-atp	16-21	ATP binding cassette subfamily C member 8	Homo sapiens	188-193
29057540-9	2017	These results show that AMPK activation augments K-ATP currents in presumed dopamine neurons in the VTA and SNC, although diazoxide-evoked currents remain less robust in the VTA.	k-atp	49-54	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	24-28
32817784-0	2020	The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes.	k-atp	18-23	stromal interaction molecule 1	Rattus norvegicus	61-66
32817784-0	2020	The mitochondrial K-ATP channel opener diazoxide upregulates STIM1 and Orai1 via ROS and the MAPK pathway in adult rat cardiomyocytes.	k-atp	18-23	ORAI calcium release-activated calcium modulator 1	Rattus norvegicus	71-76
27908292-14	2016	CONCLUSIONS: In K-ATP CHI patients managed by medical treatment only, severity is reduced over time in the majority, including those with compound heterozygous and homozygous mutations in ABCC8/KCNJ11.	k-atp	16-21	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	194-200
24875176-3	2014	Moreover, AMPK has been shown to regulate K-ATP function in a variety of tissues including pancreas, cardiac myocytes, and hypothalamus.	k-atp	42-47	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	10-14
27267246-2	2016	We used patch pipettes to record currents and potentials to investigate effects of AMPK on K-ATP currents in substantia nigra compacta (SNC) dopamine neurons in slices of rat midbrain.	k-atp	91-96	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	83-87
24875176-5	2014	We found that bath or intracellular application of the AMPK activators A769662 and PT1 augmented tolbutamide-sensitive K-ATP currents evoked by NMDA receptor stimulation.	k-atp	119-124	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	55-59
24875176-7	2014	AMPK augmentation of NMDA-induced K-ATP current was also blocked by intracellular BAPTA and by inhibitors of nitric oxide synthase and guanylyl cyclase.	k-atp	34-39	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	0-4
24875176-10	2014	These studies show that AMPK augments NMDA-induced K-ATP currents by a Ca(2+)-dependent process that involves nitric oxide and cGMP.	k-atp	51-56	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	24-28
24875176-11	2014	By augmenting K-ATP currents, AMPK activation would be expected to dampen the excitatory effect of glutamate-mediated transmission in the STN.	k-atp	14-19	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	30-34
15258252-8	2004	As measured in the inside-out configuration of the patch-clamp method, SUR2x(D834N, E1471)/Kir6.2 channels mediated significantly larger currents in the presence of internal 1 mM Na-ATP than K-ATP alone or Mg-ATP.	k-atp	191-196	ATP binding cassette subfamily C member 9	Homo sapiens	71-75
18243136-3	2008	Elevated concentrations of glucose inhibit AK1 expression and AK1 immunoprecipitates with the Kir6.2 subunit of K-ATP.	k-atp	112-117	adenylate kinase 1	Homo sapiens	62-65
18243136-3	2008	Elevated concentrations of glucose inhibit AK1 expression and AK1 immunoprecipitates with the Kir6.2 subunit of K-ATP.	k-atp	112-117	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	94-100
15258252-8	2004	As measured in the inside-out configuration of the patch-clamp method, SUR2x(D834N, E1471)/Kir6.2 channels mediated significantly larger currents in the presence of internal 1 mM Na-ATP than K-ATP alone or Mg-ATP.	k-atp	191-196	potassium inwardly rectifying channel subfamily J member 11	Homo sapiens	91-97
15258252-12	2004	Nicorandil activated SUR2x(D834N, E1471Q)/Kir6.2 channels more strongly in the presence of Na-ATP than K-ATP alone, whereas the reverse was true for wild-type SUR2x/Kir6.2 channels.	k-atp	103-108	ATP binding cassette subfamily C member 9	Homo sapiens	21-25
14716489-0	2004	SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes.	k-atp	18-23	serum/glucocorticoid regulated kinase 1 L homeolog	Xenopus laevis	0-4