PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 8717139-6 1996 In addition, BAP induces secondary floral buds in the axils of perianth members of ap2-6, ap3-1 and ag mutants, and accentuates the phenotype of the ap2-1 mutant to resemble the ap2-6 mutant. benzylaminopurine 13-16 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 83-86 8717139-6 1996 In addition, BAP induces secondary floral buds in the axils of perianth members of ap2-6, ap3-1 and ag mutants, and accentuates the phenotype of the ap2-1 mutant to resemble the ap2-6 mutant. benzylaminopurine 13-16 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 90-93 8717139-6 1996 In addition, BAP induces secondary floral buds in the axils of perianth members of ap2-6, ap3-1 and ag mutants, and accentuates the phenotype of the ap2-1 mutant to resemble the ap2-6 mutant. benzylaminopurine 13-16 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 149-152 8717139-6 1996 In addition, BAP induces secondary floral buds in the axils of perianth members of ap2-6, ap3-1 and ag mutants, and accentuates the phenotype of the ap2-1 mutant to resemble the ap2-6 mutant. benzylaminopurine 13-16 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 83-88 8581972-10 1995 TRH (0.1-10 microM) caused a transient increase in [Ca2+]i in 70-90% of bAP cells and in 60-90% of the responding cells also caused a sustained increased FM 1-43 fluorescence. benzylaminopurine 72-75 thyrotropin releasing hormone Rattus norvegicus 0-3 7486797-8 1995 Both TAP and BAP were significantly correlated with GGT in RA (P < 0.001 and P < 0.02, respectively). benzylaminopurine 13-16 gamma-glutamyltransferase 1 Homo sapiens 52-55 8581972-16 1995 The Ca(2+)-ATPase inhibitor thapsigargin reduced the number of bAP cells displaying TRH-induced increases in [Ca2+]i and membrane-turnover from 74% to 18%, but did not affect the changes in [Ca2+]i or FM 1-43 fluorescence caused by PMA or NH4Cl. benzylaminopurine 63-66 thyrotropin releasing hormone Rattus norvegicus 84-87 7770519-4 1995 It was found that the inhibitory effects of BA on root and hypocotyl elongation were partially blocked by the action of ethylene inhibitors or ethylene-resistant mutations (ein1-1 and ein2-1). benzylaminopurine 44-46 Signal transduction histidine kinase, hybrid-type, ethylene sensor Arabidopsis thaliana 173-179 12228453-5 1995 CHS mRNA levels increased within 2 h of BA spray application, and peaked by 3 h. Levels of PAL1 mRNA did not increase within 6 h of BA spray. benzylaminopurine 40-42 Chalcone and stilbene synthase family protein Arabidopsis thaliana 0-3 7770519-4 1995 It was found that the inhibitory effects of BA on root and hypocotyl elongation were partially blocked by the action of ethylene inhibitors or ethylene-resistant mutations (ein1-1 and ein2-1). benzylaminopurine 44-46 NRAMP metal ion transporter family protein Arabidopsis thaliana 184-188 7766046-6 1995 The recessive cyr1 mutation causes tenfold decreased sensitivity to benzyladenine in a root-elongation assay but does not confer resistance of roots to indole-3-acetic acid, the ethylene precursor 1-aminocyclopropane-1-carboxylic acid, or abscisic acid. benzylaminopurine 68-81 VEFS-Box of polycomb protein Arabidopsis thaliana 14-18 7607606-2 1995 The aim of this work was to study the possible correlation among serum bAP and levels of BGP measured by two different methods: an IRMA which only detects intact-BGP and a RIA which detects intact-BGP and carboxyterminal fragments (C-terminal BGP) in healthy post-menopausal control women and in a group of patients with post-menopausal osteoporosis. benzylaminopurine 71-74 bone gamma-carboxyglutamate protein Homo sapiens 89-92 7765000-6 1994 Northern blot analysis of the CR9 transcript showed the level of the mRNA (0.7 kb) to decrease tenfold within 4 h of BA treatment, i.e. well before BA-induced cotyledon expansion was observed. benzylaminopurine 117-119 light-regulated protein-like Cucumis sativus 30-33 8203728-5 1994 It has been suggested that the enzyme involved in the N-terminal cleavage of amyloid precursor peptide to generate BAP is a chymotrypsin-like serine protease such as cathepsin G. benzylaminopurine 115-118 cathepsin G Homo sapiens 166-177 7526352-4 1994 BAP shows a low intraindividual variation in M0 disease, and was within normal limits in 18 patients following radical prostatectomy with a PSA < 0.1 ng/ml. benzylaminopurine 0-3 kallikrein related peptidase 3 Homo sapiens 140-143 7526352-6 1994 The change of BAP was concordant with PSA in 69% of 49 cases of M1 disease, although there are marked differences in the rates of change of the two markers. benzylaminopurine 14-17 kallikrein related peptidase 3 Homo sapiens 38-41 7526352-7 1994 A nadir of PSA < or = 10 ng/ml after androgen blockade in M1 disease was associated with a high probability of a normal BAP. benzylaminopurine 123-126 kallikrein related peptidase 3 Homo sapiens 11-14 8075399-2 1994 20 within 4 h. Induction of cim 1 mRNA accumulation occurred at benzyladenine concentrations as low as 10(-8) M. Furthermore, cim 1 mRNA accumulation was stimulated in the absence of cytokinin by staurosporine (an inhibitor of protein kinases) and inhibited in the presence of cytokinin by okadaic acid (an inhibitor of protein phosphatases 1 and 2a), suggesting that cim 1 accumulation in response to cytokinin is dependent on cytokinin-induced dephosphorylation of one or more cellular proteins. benzylaminopurine 64-77 cytokinin induced message Glycine max 28-33 8075399-2 1994 20 within 4 h. Induction of cim 1 mRNA accumulation occurred at benzyladenine concentrations as low as 10(-8) M. Furthermore, cim 1 mRNA accumulation was stimulated in the absence of cytokinin by staurosporine (an inhibitor of protein kinases) and inhibited in the presence of cytokinin by okadaic acid (an inhibitor of protein phosphatases 1 and 2a), suggesting that cim 1 accumulation in response to cytokinin is dependent on cytokinin-induced dephosphorylation of one or more cellular proteins. benzylaminopurine 64-77 cytokinin induced message Glycine max 126-131 8075399-2 1994 20 within 4 h. Induction of cim 1 mRNA accumulation occurred at benzyladenine concentrations as low as 10(-8) M. Furthermore, cim 1 mRNA accumulation was stimulated in the absence of cytokinin by staurosporine (an inhibitor of protein kinases) and inhibited in the presence of cytokinin by okadaic acid (an inhibitor of protein phosphatases 1 and 2a), suggesting that cim 1 accumulation in response to cytokinin is dependent on cytokinin-induced dephosphorylation of one or more cellular proteins. benzylaminopurine 64-77 cytokinin induced message Glycine max 126-131 8146158-5 1994 In addition, of the various phytohormones tested, cytokinin (N6-benzylaminopurine) specifically increases wpk4 mRNA levels regardless of the light conditions, whereas in the presence of a cytokinin antagonist the level of wpk4 mRNA is not increased by either light or nutrient deprivation. benzylaminopurine 61-81 CBL-interacting protein kinase 19 Triticum aestivum 106-110 7765000-6 1994 Northern blot analysis of the CR9 transcript showed the level of the mRNA (0.7 kb) to decrease tenfold within 4 h of BA treatment, i.e. well before BA-induced cotyledon expansion was observed. benzylaminopurine 148-150 light-regulated protein-like Cucumis sativus 30-33 7765000-8 1994 The expression of the CR9 gene was repressed specifically by cytokinins (BA, isopentenyladenine and t-zeatin), but not by adenine or 2,4-dichlorophenoxyacetic acid (auxin). benzylaminopurine 73-75 light-regulated protein-like Cucumis sativus 22-25 24196174-1 1993 Green Protocorm-like Bodies (PLB) with high multiplication capacity were induced from shoot tips of flower stalk buds having 1 or 2 leaf primordia using New Dogashima Medium (NDM) containing 0.1 mg l(-1) alpha-naphthaleneacetic acid (NAA) and 1 mg 1(-1) 6-benzylaminopurine (BAP). benzylaminopurine 254-273 phospholamban Homo sapiens 29-32 24196174-1 1993 Green Protocorm-like Bodies (PLB) with high multiplication capacity were induced from shoot tips of flower stalk buds having 1 or 2 leaf primordia using New Dogashima Medium (NDM) containing 0.1 mg l(-1) alpha-naphthaleneacetic acid (NAA) and 1 mg 1(-1) 6-benzylaminopurine (BAP). benzylaminopurine 275-278 phospholamban Homo sapiens 29-32 34798465-4 2022 The present study demonstrated that PIF3 and PIF5 can slightly repress anthocyanin accumulation under NaCl, low nitrogen (-N), or 6-BA treatments; in contrast, PIF4 can significantly repress anthocyanin accumulation. benzylaminopurine 130-134 phytochrome interacting factor 3 Arabidopsis thaliana 36-40 8344949-2 1993 Since BAP begins at the aspartate residue (Asp1, or codon 672 of the amyloid precursor protein (APP)770 transcript), the ability of several proteases to cleave the peptide bond methionine-Asp1 (M/D) was evaluated by using peptides and recombinant APP molecules as substrates. benzylaminopurine 6-9 beta-secretase 2 Homo sapiens 43-47 8344949-2 1993 Since BAP begins at the aspartate residue (Asp1, or codon 672 of the amyloid precursor protein (APP)770 transcript), the ability of several proteases to cleave the peptide bond methionine-Asp1 (M/D) was evaluated by using peptides and recombinant APP molecules as substrates. benzylaminopurine 6-9 beta-secretase 2 Homo sapiens 188-192 8344949-6 1993 Incubation of cathepsin G with soluble protease nexin-2 obtained from recombinant APP (APP-REP) derivatives resulted in proteolytic cleavage at or near the amino terminus of BAP. benzylaminopurine 174-177 cathepsin G Homo sapiens 14-25 8344949-6 1993 Incubation of cathepsin G with soluble protease nexin-2 obtained from recombinant APP (APP-REP) derivatives resulted in proteolytic cleavage at or near the amino terminus of BAP. benzylaminopurine 174-177 amyloid beta precursor protein Homo sapiens 87-94 8344949-7 1993 Cathepsin G-mediated cleavage was also observed in the domain representing the amino terminus of BAP when mature plasma membrane-associated APP-REP molecules were used as substrates. benzylaminopurine 97-100 cathepsin G Homo sapiens 0-11 8344949-7 1993 Cathepsin G-mediated cleavage was also observed in the domain representing the amino terminus of BAP when mature plasma membrane-associated APP-REP molecules were used as substrates. benzylaminopurine 97-100 amyloid beta precursor protein Homo sapiens 140-147 8344949-8 1993 Our results strongly suggest the involvement of a chymotrypsin-like serine protease in the generation of the amino terminus of BAP beginning at Asp1. benzylaminopurine 127-130 beta-secretase 2 Homo sapiens 144-148 8379619-11 1993 Significant concentrations of PAH up to 269 micrograms PAH m-3 (4 micrograms BaP m-3) occurred during ignition of the cupola furnace. benzylaminopurine 77-80 phenylalanine hydroxylase Homo sapiens 30-33 8379619-11 1993 Significant concentrations of PAH up to 269 micrograms PAH m-3 (4 micrograms BaP m-3) occurred during ignition of the cupola furnace. benzylaminopurine 77-80 phenylalanine hydroxylase Homo sapiens 55-58 1521167-5 1992 This difference reflected the variation of ODC gene expression; the ODC-mRNA induction was 6:1 in Ctr cells and 3:1 in BaP-tr cells. benzylaminopurine 119-122 ornithine decarboxylase, structural 1 Mus musculus 43-46 1521167-5 1992 This difference reflected the variation of ODC gene expression; the ODC-mRNA induction was 6:1 in Ctr cells and 3:1 in BaP-tr cells. benzylaminopurine 119-122 ornithine decarboxylase, structural 1 Mus musculus 68-71 16668070-0 1991 Metabolism of Benzyladenine is Impaired in a Mutant of Arabidopsis thaliana Lacking Adenine Phosphoribosyltransferase Activity. benzylaminopurine 14-27 adenine phosphoribosyltransferase Arabidopsis thaliana 84-117 16668070-6 1991 BA was also rapidly absorbed by APRT-deficient plantlets, but its conversion to BAMP was strongly reduced. benzylaminopurine 0-2 adenine phosphoribosyltransferase Arabidopsis thaliana 32-36 16668070-10 1991 Further, nondenaturing isoelectric focusing analysis of APRT activity in leaf extracts indicated that the enzyme activities which metabolize adenine and BA into their corresponding riboside-5"-monophosphate in extracts of wild-type plantlets have the same apparent isoelectric point. benzylaminopurine 153-155 adenine phosphoribosyltransferase Arabidopsis thaliana 56-60 16668070-12 1991 Thus, these results demonstrate that APRT is the main enzyme which converts BA to its nucleotide form in young A. thaliana plants and that the ribophosphorylation of BA is not a prerequisite of its absorption by the plantlets. benzylaminopurine 76-78 adenine phosphoribosyltransferase Arabidopsis thaliana 37-41 34686779-7 2022 Overexpression of Nrf2 in K562 and KG1a completely inhibited ROS production and rescued cells from VAL/BaP 0.1 mM/VBaP killing. benzylaminopurine 103-106 NFE2 like bZIP transcription factor 2 Homo sapiens 18-22 34859720-8 2022 IGF-1, GH and BAP results were generally less affected by added biotin and significant bias (>10%) was observed only when the biotin concentration was 100 ng/mL (IGF-1 and GH) or 500 ng/mL (BAP). benzylaminopurine 190-193 insulin like growth factor 1 Homo sapiens 0-5 34798465-8 2022 Consistently, the anthocyanin content in pap1-D/35S::PIF4 and 35S::PAP1/35S::PIF4 seedlings was markedly lower than that in pap1-D and 35S::PAP1 under 6-BA, MeJA, -N, and NaCl stresses, implying that overexpression of PIF4 suppresses anthocyanin accumulation in pap1-D and 35S::PAP1. benzylaminopurine 151-155 phytochrome interacting factor 4 Arabidopsis thaliana 218-222 12231940-7 1993 Subculture of calli grown on 2,4-dichlorophenoxyacetic acid in a medium containing benzyladenine triggered a slow decrease in PPO activity and dramatic increases in peroxidase and tyramine hydroxycinnamoyl transferase (THT) activities. benzylaminopurine 83-96 protoporphyrinogen oxidase, chloroplastic Nicotiana tabacum 126-129 12231940-7 1993 Subculture of calli grown on 2,4-dichlorophenoxyacetic acid in a medium containing benzyladenine triggered a slow decrease in PPO activity and dramatic increases in peroxidase and tyramine hydroxycinnamoyl transferase (THT) activities. benzylaminopurine 83-96 peroxidase N1 Nicotiana tabacum 165-175 12231940-7 1993 Subculture of calli grown on 2,4-dichlorophenoxyacetic acid in a medium containing benzyladenine triggered a slow decrease in PPO activity and dramatic increases in peroxidase and tyramine hydroxycinnamoyl transferase (THT) activities. benzylaminopurine 83-96 tyramine N-feruloyltransferase 4/11 Nicotiana tabacum 180-217 12231940-7 1993 Subculture of calli grown on 2,4-dichlorophenoxyacetic acid in a medium containing benzyladenine triggered a slow decrease in PPO activity and dramatic increases in peroxidase and tyramine hydroxycinnamoyl transferase (THT) activities. benzylaminopurine 83-96 tyramine N-feruloyltransferase 4/11 Nicotiana tabacum 219-222 8473306-5 1993 APC had no effect on the lysis time of BAP but shortened the lysis time of NHP to that of BAP. benzylaminopurine 90-93 APC regulator of WNT signaling pathway Homo sapiens 0-3 8473306-8 1993 Both fractions together, but neither alone, prolonged the lysis time of BAP, an effect which could be reversed by APC. benzylaminopurine 72-75 APC regulator of WNT signaling pathway Homo sapiens 114-117 2091832-2 1990 Amyloid plaques found in the brains of Alzheimer"s diseased patients are composed of the 42 amino acid beta-amyloid peptide (BAP) which is processed out of the larger amyloid precursor protein (APP). benzylaminopurine 125-128 amyloid beta precursor protein Homo sapiens 103-123 2091832-2 1990 Amyloid plaques found in the brains of Alzheimer"s diseased patients are composed of the 42 amino acid beta-amyloid peptide (BAP) which is processed out of the larger amyloid precursor protein (APP). benzylaminopurine 125-128 amyloid beta precursor protein Homo sapiens 167-192 34798465-4 2022 The present study demonstrated that PIF3 and PIF5 can slightly repress anthocyanin accumulation under NaCl, low nitrogen (-N), or 6-BA treatments; in contrast, PIF4 can significantly repress anthocyanin accumulation. benzylaminopurine 130-134 phytochrome interacting factor 3-like 6 Arabidopsis thaliana 45-49 35487446-1 2022 OBJECTIVE: The effects of benzo (alpha) pyrene (BaP) on chaperone mediated autophagy (CMA) through heat shock protein 90 (HSP90) and hypoxia- inducible factor-1 (HIF-1) is studied by RNA interference and subcutaneous tumor formation technique in nude mice. benzylaminopurine 48-51 heat shock protein, 2 Mus musculus 99-120 34717573-11 2021 Partial perfusion parameters of BAP and AEF Q10 were positively correlated with VEGF (p value range is 0.001-0.016, rhovalue range is 0.398-0.570), meanwhile some perfusion parameters of PAP and PI were negatively correlated with VEGF (p value range is 0.001-0.040, rho value range is - 0.657-0.343). benzylaminopurine 32-35 vascular endothelial growth factor A Homo sapiens 80-84 34332249-6 2021 Video analysis and qRT-PCR data found that zebrafish under 6-BA exposure showed obvious cardiovascular morphological abnormalities and dysfunction, and the mRNA levels of cardiovascular-related genes (nkx2.5, gata4, myl7, vegfaa and vegfab) were significantly down-regulated. benzylaminopurine 59-63 NK2 homeobox 5 Danio rerio 201-207 34332249-6 2021 Video analysis and qRT-PCR data found that zebrafish under 6-BA exposure showed obvious cardiovascular morphological abnormalities and dysfunction, and the mRNA levels of cardiovascular-related genes (nkx2.5, gata4, myl7, vegfaa and vegfab) were significantly down-regulated. benzylaminopurine 59-63 GATA binding protein 4 Danio rerio 209-214 34332249-6 2021 Video analysis and qRT-PCR data found that zebrafish under 6-BA exposure showed obvious cardiovascular morphological abnormalities and dysfunction, and the mRNA levels of cardiovascular-related genes (nkx2.5, gata4, myl7, vegfaa and vegfab) were significantly down-regulated. benzylaminopurine 59-63 myosin, light chain 7, regulatory Danio rerio 216-220 34332249-6 2021 Video analysis and qRT-PCR data found that zebrafish under 6-BA exposure showed obvious cardiovascular morphological abnormalities and dysfunction, and the mRNA levels of cardiovascular-related genes (nkx2.5, gata4, myl7, vegfaa and vegfab) were significantly down-regulated. benzylaminopurine 59-63 vascular endothelial growth factor Aa Danio rerio 222-228 34578310-4 2021 To facilitate tracking of Env in live cells, we adapted an Env tagging method and introduced a biotin acceptor peptide (BAP) into the V4 loop of Env gp120, enabling sensitive fluorescent tracking of V4-biotinylated Env. benzylaminopurine 120-123 endogenous retrovirus group K member 20 Homo sapiens 26-29 34578310-4 2021 To facilitate tracking of Env in live cells, we adapted an Env tagging method and introduced a biotin acceptor peptide (BAP) into the V4 loop of Env gp120, enabling sensitive fluorescent tracking of V4-biotinylated Env. benzylaminopurine 120-123 endogenous retrovirus group K member 20 Homo sapiens 145-148 34578310-4 2021 To facilitate tracking of Env in live cells, we adapted an Env tagging method and introduced a biotin acceptor peptide (BAP) into the V4 loop of Env gp120, enabling sensitive fluorescent tracking of V4-biotinylated Env. benzylaminopurine 120-123 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 149-154 34578310-4 2021 To facilitate tracking of Env in live cells, we adapted an Env tagging method and introduced a biotin acceptor peptide (BAP) into the V4 loop of Env gp120, enabling sensitive fluorescent tracking of V4-biotinylated Env. benzylaminopurine 120-123 endogenous retrovirus group K member 20 Homo sapiens 215-218 35569034-5 2022 Similar associations showed BAP with %BOP (ebeta = 1.121; 95% CI: 1.042-1.205) and proportion of sites with PPD >= 4 mm (%PPD4) (ebeta = 1.080; 95% CI: 1.005-1.161), and sclerostin with %BOP (ebeta = 1.308; 95% CI: 1.005-1.704). benzylaminopurine 28-31 BOP Homo sapiens 37-41 35569034-5 2022 Similar associations showed BAP with %BOP (ebeta = 1.121; 95% CI: 1.042-1.205) and proportion of sites with PPD >= 4 mm (%PPD4) (ebeta = 1.080; 95% CI: 1.005-1.161), and sclerostin with %BOP (ebeta = 1.308; 95% CI: 1.005-1.704). benzylaminopurine 28-31 sclerostin Homo sapiens 170-180 35569034-5 2022 Similar associations showed BAP with %BOP (ebeta = 1.121; 95% CI: 1.042-1.205) and proportion of sites with PPD >= 4 mm (%PPD4) (ebeta = 1.080; 95% CI: 1.005-1.161), and sclerostin with %BOP (ebeta = 1.308; 95% CI: 1.005-1.704). benzylaminopurine 28-31 BOP Homo sapiens 186-190 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 peroxidase 1 Zea mays 115-125 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 ascorbate peroxidase 2 Zea mays 127-130 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 glutathione reductase 1 Zea mays 133-154 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 glutathione reductase 1 Zea mays 156-158 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 glutathione dehydroascorbate reductase2 Zea mays 161-187 34539688-7 2021 In addition to this, exogenous 6-BA also reduced the accumulation of O 2 - , H2O2, and MDA, increased ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), and monodehydroascorbate reductase (MDHAR) activity, and enhanced ascorbic acid (AsA), and reduced glutathione (GSH) concentration through the regulation of the efficiency of the AsA-GSH cycle system in maize plants. benzylaminopurine 31-35 glutathione dehydroascorbate reductase2 Zea mays 189-193 35487446-1 2022 OBJECTIVE: The effects of benzo (alpha) pyrene (BaP) on chaperone mediated autophagy (CMA) through heat shock protein 90 (HSP90) and hypoxia- inducible factor-1 (HIF-1) is studied by RNA interference and subcutaneous tumor formation technique in nude mice. benzylaminopurine 48-51 heat shock protein, 2 Mus musculus 122-127 35487446-5 2022 A549 cells were treated with 0.1 mumol/L, 1 mumol/L and 10 mumol/L BaP for 24 h, EPO and HIF-1alpha concentration and HIF-1alpha protein expression were detected by Elisa and Western blot; A549 cells were treated with 10 mumol/L BaP and HIF-1alpha inhibitor for 24 h, qPCR, Western blot and Immunofluorescence method were used to detect the expression of HSP90alpha, HSC70 and Lamp-2A. benzylaminopurine 229-232 hypoxia inducible factor 1, alpha subunit Mus musculus 118-128 35487446-7 2022 The concentration of EPO and HIF-1alpha and the expression of HIF-1alpha protein in A549 cells was increased by 10 mumol/L BaP (P < 0.05); with HIF-1alpha inhibitors treated, HSP90alpha, HSC70, Lamp-2A mRNA and protein expression and the fluorescence intensity of HSP90alpha was decreased of A549 cells (P < 0.05). benzylaminopurine 123-126 erythropoietin Mus musculus 21-24 35487446-7 2022 The concentration of EPO and HIF-1alpha and the expression of HIF-1alpha protein in A549 cells was increased by 10 mumol/L BaP (P < 0.05); with HIF-1alpha inhibitors treated, HSP90alpha, HSC70, Lamp-2A mRNA and protein expression and the fluorescence intensity of HSP90alpha was decreased of A549 cells (P < 0.05). benzylaminopurine 123-126 hypoxia inducible factor 1, alpha subunit Mus musculus 29-39 35487446-7 2022 The concentration of EPO and HIF-1alpha and the expression of HIF-1alpha protein in A549 cells was increased by 10 mumol/L BaP (P < 0.05); with HIF-1alpha inhibitors treated, HSP90alpha, HSC70, Lamp-2A mRNA and protein expression and the fluorescence intensity of HSP90alpha was decreased of A549 cells (P < 0.05). benzylaminopurine 123-126 hypoxia inducible factor 1, alpha subunit Mus musculus 62-72 35487446-7 2022 The concentration of EPO and HIF-1alpha and the expression of HIF-1alpha protein in A549 cells was increased by 10 mumol/L BaP (P < 0.05); with HIF-1alpha inhibitors treated, HSP90alpha, HSC70, Lamp-2A mRNA and protein expression and the fluorescence intensity of HSP90alpha was decreased of A549 cells (P < 0.05). benzylaminopurine 123-126 heat shock protein 8 Mus musculus 187-192 35487446-7 2022 The concentration of EPO and HIF-1alpha and the expression of HIF-1alpha protein in A549 cells was increased by 10 mumol/L BaP (P < 0.05); with HIF-1alpha inhibitors treated, HSP90alpha, HSC70, Lamp-2A mRNA and protein expression and the fluorescence intensity of HSP90alpha was decreased of A549 cells (P < 0.05). benzylaminopurine 123-126 lysosomal-associated membrane protein 2 Mus musculus 194-201 35149407-5 2022 While under a continuous exposure regime, 6-BA at 0.2 mg/L was able to cause hyperactive locomotion and transcription of genes related to neurogenesis (gnrh3 and nestin) and endocrine systems (cyp19a and fshb) in 5 dpf larvae. benzylaminopurine 42-46 gonadotropin-releasing hormone 3 Danio rerio 152-157 35124201-5 2022 6-Benzylaminopurines showed comparable CDK2 inhibitory activity to 6-anilinopurines, however, the PDGFRalpha and FLT3-ITD inhibition was strongly suppressed. benzylaminopurine 0-20 cyclin dependent kinase 2 Homo sapiens 39-43 35124201-5 2022 6-Benzylaminopurines showed comparable CDK2 inhibitory activity to 6-anilinopurines, however, the PDGFRalpha and FLT3-ITD inhibition was strongly suppressed. benzylaminopurine 0-20 platelet derived growth factor receptor alpha Homo sapiens 98-108 35388561-6 2022 In maize, similary, BAP treatment increased the vegetative phage by inhibiting the expression of ZCN8, an ortholog of Hd3a. benzylaminopurine 20-23 ZCN8 protein Zea mays 97-101 35149407-5 2022 While under a continuous exposure regime, 6-BA at 0.2 mg/L was able to cause hyperactive locomotion and transcription of genes related to neurogenesis (gnrh3 and nestin) and endocrine systems (cyp19a and fshb) in 5 dpf larvae. benzylaminopurine 42-46 nestin Danio rerio 162-168 35149407-5 2022 While under a continuous exposure regime, 6-BA at 0.2 mg/L was able to cause hyperactive locomotion and transcription of genes related to neurogenesis (gnrh3 and nestin) and endocrine systems (cyp19a and fshb) in 5 dpf larvae. benzylaminopurine 42-46 cytochrome P450, family 19, subfamily A, polypeptide 1a Danio rerio 193-199 35149407-5 2022 While under a continuous exposure regime, 6-BA at 0.2 mg/L was able to cause hyperactive locomotion and transcription of genes related to neurogenesis (gnrh3 and nestin) and endocrine systems (cyp19a and fshb) in 5 dpf larvae. benzylaminopurine 42-46 follicle stimulating hormone subunit beta Danio rerio 204-208 35149407-9 2022 In silico simulations demonstrated potential for binding of 6-BA to estrogen receptor alpha (ERa) and cytochrome P450 aromatase (CYP19A). benzylaminopurine 60-64 estrogen receptor 1 Danio rerio 68-91 35149407-9 2022 In silico simulations demonstrated potential for binding of 6-BA to estrogen receptor alpha (ERa) and cytochrome P450 aromatase (CYP19A). benzylaminopurine 60-64 cytochrome P450, family 19, subfamily A, polypeptide 1a Danio rerio 129-135 2903459-1 1988 The longest open reading frames (ORFs) of three different cDNAs ([10, 12, 18, 26], and this report) contain the exact 42 amino acid (aa) sequence of the beta-amyloid peptide (BAP) which is selectively deposited in Alzheimer"s diseased (AD) brains. benzylaminopurine 175-178 amyloid beta precursor protein Homo sapiens 153-173 24233144-6 1989 3-indolebutyric acid (2.5 muM) and 6-benzylaminopurine (8.8 muM) increased the productivity of solasodine by 100%. benzylaminopurine 35-54 latexin Homo sapiens 60-63 6175497-5 1981 Only the 1000 ppm BAP treatment induced elevated blood plasma levels of AFP and GGT-positive hepatic cell foci. benzylaminopurine 18-21 alpha-fetoprotein Rattus norvegicus 72-75 2894954-9 1988 The effect of these cytochrome P-450 inducers and inhibitors on the metabolism of 3H-benzo(a)pyrene (BaP) in rat hepatocytes was similar to their effect on TCDD metabolism. benzylaminopurine 101-104 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 20-36 3918856-7 1985 In contrast, two inhibitors of phospholipase A2, dibromoacetophenone (BAP) and U10029A, inhibited spontaneous PRL release. benzylaminopurine 70-73 phospholipase A2 group IB Rattus norvegicus 31-47 3918856-10 1985 The phospholipase A2 inhibitor BAP blocked TRH- and vasoactive intestinal peptide-induced PRL release, whereas U10029A blocked cAMP-induced and blunted TRH- and vasoactive intestinal peptide-induced PRL release. benzylaminopurine 31-34 phospholipase A2 group IB Rattus norvegicus 4-20 6865463-3 1983 Bilateral systolic brachial artery pressure (BAP) was measured by Doppler instrumentation to obtain a "BAP index": BAP1 = (operated side BAP/control side BAP). benzylaminopurine 103-106 BRCA1 associated protein 1 Homo sapiens 115-119 6865463-3 1983 Bilateral systolic brachial artery pressure (BAP) was measured by Doppler instrumentation to obtain a "BAP index": BAP1 = (operated side BAP/control side BAP). benzylaminopurine 103-106 BRCA1 associated protein 1 Homo sapiens 115-119 6175497-5 1981 Only the 1000 ppm BAP treatment induced elevated blood plasma levels of AFP and GGT-positive hepatic cell foci. benzylaminopurine 18-21 gamma-glutamyltransferase 1 Rattus norvegicus 80-83 16656573-8 1967 6-Methylpurine inhibited the development of proteinase activity, and this inhibition was only partially restored by benzyladenine.A proteinase was partially purified from the cotyledons of 2-day-old squash seedlings and its synthesis was shown to be under the control of the embryonic axis. benzylaminopurine 116-129 endogenous retrovirus group K member 25 Homo sapiens 132-142 34051271-4 2021 The role of aryl hydrocarbon receptor (AhR) and NF-kappaB signaling pathways involved in BaP-induced oxidative stress and inflammation was further investigated. benzylaminopurine 89-92 aryl hydrocarbon receptor Homo sapiens 39-42 34051271-4 2021 The role of aryl hydrocarbon receptor (AhR) and NF-kappaB signaling pathways involved in BaP-induced oxidative stress and inflammation was further investigated. benzylaminopurine 89-92 aryl hydrocarbon receptor Homo sapiens 12-37 34051271-4 2021 The role of aryl hydrocarbon receptor (AhR) and NF-kappaB signaling pathways involved in BaP-induced oxidative stress and inflammation was further investigated. benzylaminopurine 89-92 nuclear factor kappa B subunit 1 Homo sapiens 48-57 34051271-7 2021 Furthermore, BaP treatment of HUVECs activated AhR and NF-kappaB signaling pathways, and promoted reactive oxygen species generation and inflammatory cytokine release. benzylaminopurine 13-16 aryl hydrocarbon receptor Homo sapiens 47-50 34051271-7 2021 Furthermore, BaP treatment of HUVECs activated AhR and NF-kappaB signaling pathways, and promoted reactive oxygen species generation and inflammatory cytokine release. benzylaminopurine 13-16 nuclear factor kappa B subunit 1 Homo sapiens 55-64 34051271-8 2021 The current findings suggest that BaP induced inflammatory cytokine release from HUVECs through oxidative stress accompanied with AhR and NF-kappaB pathway activation. benzylaminopurine 34-37 aryl hydrocarbon receptor Homo sapiens 130-133 34051271-8 2021 The current findings suggest that BaP induced inflammatory cytokine release from HUVECs through oxidative stress accompanied with AhR and NF-kappaB pathway activation. benzylaminopurine 34-37 nuclear factor kappa B subunit 1 Homo sapiens 138-147 33288423-16 2021 The ability of the ratio (FGF23*bAP/CTX) to distinguish patients with bone fragility was good, with a ROC AUC of 0.701. benzylaminopurine 32-35 fibroblast growth factor 23 Homo sapiens 26-31 32860851-4 2020 It was found that integrin alpha4 (ITGA4) expression levels are significantly up-regulated and the Hedgehog pathway is highly activated in arsenic plus BaP co-exposure-transformed human bronchial epithelial cells. benzylaminopurine 152-155 integrin subunit alpha 4 Homo sapiens 18-33 32860851-4 2020 It was found that integrin alpha4 (ITGA4) expression levels are significantly up-regulated and the Hedgehog pathway is highly activated in arsenic plus BaP co-exposure-transformed human bronchial epithelial cells. benzylaminopurine 152-155 integrin subunit alpha 4 Homo sapiens 35-40 32860851-8 2020 These findings indicate that ITGA4 up-regulation activates the Hedgehog pathway to enhance the CSC-like property and tumorigenicity of arsenic and BaP co-exposure-transformed cells, offering new mechanistic insight for the synergistic carcinogenic effect of arsenic and BaP co-exposure. benzylaminopurine 147-150 integrin subunit alpha 4 Homo sapiens 29-34 32860851-8 2020 These findings indicate that ITGA4 up-regulation activates the Hedgehog pathway to enhance the CSC-like property and tumorigenicity of arsenic and BaP co-exposure-transformed cells, offering new mechanistic insight for the synergistic carcinogenic effect of arsenic and BaP co-exposure. benzylaminopurine 270-273 integrin subunit alpha 4 Homo sapiens 29-34 32102689-15 2020 The levels of bAP and CTX showed a positive correlation. benzylaminopurine 14-17 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 22-25 32186757-6 2020 Furthermore, an association between the PON2 S331C gene polymorphism and the serum levels of AOPP, ROMs and BAP was found. benzylaminopurine 108-111 paraoxonase 2 Homo sapiens 40-44 32102689-16 2020 Both circulating bAP and CTX levels showed also positive correlations with PTH levels. benzylaminopurine 17-20 parathyroid hormone Homo sapiens 75-78 32587434-4 2020 Propagation via shoot culture was achieved on 1/2 MS medium with 1 microM benzyl adenine (BAP). benzylaminopurine 74-88 prohibitin 2 Homo sapiens 90-93 31367362-4 2019 The EPS productivity and yield of strain LaP with optimal production set (OPS) were, respectively, 291.0 +- 2.6 mg and 13.5 +- 0.7%, and the cost of OPS can be saved by about 31.6%, while that for strain BaP were 280.7 +- 2.5 mg and 13.0 +- 0.7%, respectively, and with 31.6% saved as well. benzylaminopurine 204-207 LAP Homo sapiens 41-44 31112706-3 2019 Urinary excretion of BaP and cotinine (a metabolite of nicotine) increased in a time-dependent manner increased after supplementation with APS (BaP, 2.23-fold; cotinine, 2.64-fold), propolis (BaP, 1.30-fold; cotinine, 2.08-fold), and the mixture (BaP, 2.33-fold; cotinine, 2.28-fold) compared with smoker control. benzylaminopurine 21-24 BAR/IMD domain containing adaptor protein 2 Homo sapiens 144-150 31112706-3 2019 Urinary excretion of BaP and cotinine (a metabolite of nicotine) increased in a time-dependent manner increased after supplementation with APS (BaP, 2.23-fold; cotinine, 2.64-fold), propolis (BaP, 1.30-fold; cotinine, 2.08-fold), and the mixture (BaP, 2.33-fold; cotinine, 2.28-fold) compared with smoker control. benzylaminopurine 21-24 BRCA1 associated protein 1 Homo sapiens 192-198 31112706-3 2019 Urinary excretion of BaP and cotinine (a metabolite of nicotine) increased in a time-dependent manner increased after supplementation with APS (BaP, 2.23-fold; cotinine, 2.64-fold), propolis (BaP, 1.30-fold; cotinine, 2.08-fold), and the mixture (BaP, 2.33-fold; cotinine, 2.28-fold) compared with smoker control. benzylaminopurine 21-24 BAR/IMD domain containing adaptor protein 2 Homo sapiens 247-253 31384515-6 2019 There was a significant correlation between serum levels of BAP and osteopontin. benzylaminopurine 60-63 secreted phosphoprotein 1 Homo sapiens 68-79 31384515-10 2019 Serum levels of osteopontin and RANKL were correlated to serum levels of BAP and disease extension. benzylaminopurine 73-76 secreted phosphoprotein 1 Homo sapiens 16-27 31384515-10 2019 Serum levels of osteopontin and RANKL were correlated to serum levels of BAP and disease extension. benzylaminopurine 73-76 TNF superfamily member 11 Homo sapiens 32-37 30922566-6 2019 Moreover, HTD4010 down-regulated the expression of toll-like receptor 4 (TLR4) protein, and TLR4 deficiency eliminated the protective effect of HTD4010 on BAP in mice. benzylaminopurine 155-158 toll-like receptor 4 Mus musculus 51-71 30922566-6 2019 Moreover, HTD4010 down-regulated the expression of toll-like receptor 4 (TLR4) protein, and TLR4 deficiency eliminated the protective effect of HTD4010 on BAP in mice. benzylaminopurine 155-158 toll-like receptor 4 Mus musculus 73-77 30922566-6 2019 Moreover, HTD4010 down-regulated the expression of toll-like receptor 4 (TLR4) protein, and TLR4 deficiency eliminated the protective effect of HTD4010 on BAP in mice. benzylaminopurine 155-158 toll-like receptor 4 Mus musculus 92-96 30294794-1 2019 Benzo[alpha]pyrene (BaP) can have significant role in the development of breast cancer via aryl hydrocarbon receptor (AhR) activation. benzylaminopurine 20-23 aryl hydrocarbon receptor Homo sapiens 91-116 30974902-4 2019 Local network measures significantly correlated with autism severity in ASD children and with BAP traits in fath-ASD, while no significant association emerged when considering the global measures of brain connectivity. benzylaminopurine 94-97 arylsulfatase D Homo sapiens 108-116 30841918-8 2019 Several transcription factors (i.e. SPLs, SOC1, FD, and COL) that are involved in GA, aging, and photoperiod-regulated flowering pathways were also upregulated by the 6-BA treatment. benzylaminopurine 167-171 MADS-box protein SOC1-like Malus domestica 42-46 30543962-11 2019 Coexisting of SO2 and BaP increased the protein expression of pro-fibrotic genes and TGFbetaR2 and decreased mir-30c-1-3p in vivo and in vitro. benzylaminopurine 22-25 microRNA 30c-1 Mus musculus 109-118 30543962-13 2019 All above results demonstrated that mir-30c-1-3p was involved in the synergistic pro-fibrotic effects of SO2 and BaP in lung via targeting TGFbetaR2. benzylaminopurine 113-116 microRNA 30c-1 Mus musculus 36-45 30294794-1 2019 Benzo[alpha]pyrene (BaP) can have significant role in the development of breast cancer via aryl hydrocarbon receptor (AhR) activation. benzylaminopurine 20-23 aryl hydrocarbon receptor Homo sapiens 118-121 30294794-4 2019 The aim of the present study was to examine the effect of BaP, an activator of AhR and cyclosporine A (CsA), as inhibitor of NFAT on migration and invasion of MDA-MB-231 cells. benzylaminopurine 58-61 aryl hydrocarbon receptor Homo sapiens 79-82 30726812-3 2019 This work was therefore to unravel the effects of the PI3K/Akt signaling pathway on pyroptotic and autophagic death triggered by BaP. benzylaminopurine 129-132 AKT serine/threonine kinase 1 Homo sapiens 59-62 30294794-7 2019 Activation of AhR by BaP induced invasion as well as migration in MDA-MB-231 cells, which was blocked by AhR antagonist. benzylaminopurine 21-24 aryl hydrocarbon receptor Homo sapiens 14-17 30294794-7 2019 Activation of AhR by BaP induced invasion as well as migration in MDA-MB-231 cells, which was blocked by AhR antagonist. benzylaminopurine 21-24 aryl hydrocarbon receptor Homo sapiens 105-108 30294794-9 2019 In these cells, BaP significantly reduced AhR expression while this reduction was reversed by CH-223191; however, CsA treatment lowered the AhR expression only at low dose. benzylaminopurine 16-19 aryl hydrocarbon receptor Homo sapiens 42-45 30511719-5 2019 BaP forms a hydrophobic complex with PCBs, which has allowed for the successful detection of pollutants including PCB-126, PCB-153 and PCB-118. benzylaminopurine 0-3 pyruvate carboxylase Homo sapiens 37-40 30511719-5 2019 BaP forms a hydrophobic complex with PCBs, which has allowed for the successful detection of pollutants including PCB-126, PCB-153 and PCB-118. benzylaminopurine 0-3 pyruvate carboxylase Homo sapiens 114-117 30511719-5 2019 BaP forms a hydrophobic complex with PCBs, which has allowed for the successful detection of pollutants including PCB-126, PCB-153 and PCB-118. benzylaminopurine 0-3 pyruvate carboxylase Homo sapiens 114-117 29101605-12 2018 Hence, we concluded that in all the conditions, LDLR expression was found to be a translational event of its transcription factor, SREBP-2, by the induction of insulin, BaP and UV irradiation. benzylaminopurine 169-172 low density lipoprotein receptor Homo sapiens 48-52 30726812-4 2019 Cells were treated with or without LY294002 (PI3K/Akt inhibitor) and IGF-1 (PI3K/Akt activator) before BaP exposure, and the results showed that compared with the control, the protein expression of p-Akt was markedly decreased by BaP (p < 0.05). benzylaminopurine 230-233 insulin like growth factor 1 Homo sapiens 69-74 30726812-6 2019 Furthermore, the protein expression of pyroptosis (Cleaved Caspase-1, NO, IL-1beta, IL-18), as well as LDH and the relative electrical conductivity were significantly augmented by BaP. benzylaminopurine 180-183 interleukin 1 beta Homo sapiens 74-82 30726812-6 2019 Furthermore, the protein expression of pyroptosis (Cleaved Caspase-1, NO, IL-1beta, IL-18), as well as LDH and the relative electrical conductivity were significantly augmented by BaP. benzylaminopurine 180-183 interleukin 18 Homo sapiens 84-89 30726812-8 2019 Similarly, LY294002 enhanced BaP-induced increase in the key protein expression of autophagy (Beclin-1 and LC3II), while IGF-1 weakened it. benzylaminopurine 29-32 beclin 1 Homo sapiens 94-102 30726812-9 2019 Finally, the phosphorylation of FOXO4 was clearly (p < 0.01) inhibited by BaP, and LY294002 suppressed this inhibitive effect of BaP, while IGF-1 strengthened it. benzylaminopurine 77-80 forkhead box O4 Homo sapiens 32-37 30726812-9 2019 Finally, the phosphorylation of FOXO4 was clearly (p < 0.01) inhibited by BaP, and LY294002 suppressed this inhibitive effect of BaP, while IGF-1 strengthened it. benzylaminopurine 132-135 forkhead box O4 Homo sapiens 32-37 30726812-10 2019 In conclusion, BaP was able to induce pyroptotic and autophagic death via blocking the PI3K/Akt signaling pathway in HL-7702 liver cells. benzylaminopurine 15-18 AKT serine/threonine kinase 1 Homo sapiens 92-95 30322610-4 2018 The melanogenic activity of 6-benzylaminopurine, the compound identified as the most potent, was further verified by measuring green fluorescent protein concentration in tyrp1 a: eGFP (tyrosinase-related protein 1) zebrafish and mitfa: eGFP (microphthalmia associated transcription factor) zebrafish and antioxidative activity. benzylaminopurine 28-47 tyrosinase-related protein 1a Danio rerio 170-177 30322610-4 2018 The melanogenic activity of 6-benzylaminopurine, the compound identified as the most potent, was further verified by measuring green fluorescent protein concentration in tyrp1 a: eGFP (tyrosinase-related protein 1) zebrafish and mitfa: eGFP (microphthalmia associated transcription factor) zebrafish and antioxidative activity. benzylaminopurine 28-47 tyrosinase-related protein 1a Danio rerio 185-213 30322610-4 2018 The melanogenic activity of 6-benzylaminopurine, the compound identified as the most potent, was further verified by measuring green fluorescent protein concentration in tyrp1 a: eGFP (tyrosinase-related protein 1) zebrafish and mitfa: eGFP (microphthalmia associated transcription factor) zebrafish and antioxidative activity. benzylaminopurine 28-47 melanocyte inducing transcription factor a Danio rerio 242-288 30322610-8 2018 Overall, our results indicated that 6-benzylaminopurine stimulated pigmentation through a direct mechanism, by increasing melanin content via positive regulation of tyrosinase activity in vitro, as well as up-regulating the expression of the green fluorescent protein in transgenic zebrafish in vivo. benzylaminopurine 36-55 tyrosinase Danio rerio 165-175 30130740-6 2018 GA3 and 6-BA application significantly increased the levels of zeatin riboside (ZR) by up-regulating IPT expression and gibberellic acid (GA3) but decreased the indole-3-acetic acid (IAA) content. benzylaminopurine 8-12 adenylate isopentenyltransferase 5, chloroplastic-like Gossypium hirsutum 101-104 29101605-3 2018 We observed that insulin and benzo-alpha-pyrene (BaP) induced the expression of Low-Density Lipoprotein receptor (LDLR) on HepG2 cells, thereby enhancing the uptake of LDL. benzylaminopurine 49-52 insulin Homo sapiens 17-24 29101605-3 2018 We observed that insulin and benzo-alpha-pyrene (BaP) induced the expression of Low-Density Lipoprotein receptor (LDLR) on HepG2 cells, thereby enhancing the uptake of LDL. benzylaminopurine 49-52 low density lipoprotein receptor Homo sapiens 80-112 29101605-3 2018 We observed that insulin and benzo-alpha-pyrene (BaP) induced the expression of Low-Density Lipoprotein receptor (LDLR) on HepG2 cells, thereby enhancing the uptake of LDL. benzylaminopurine 49-52 low density lipoprotein receptor Homo sapiens 114-118 29101605-5 2018 At the same time, insulin and BaP also stimulated the expression of cell cycle proteins viz., Cyclin E and Cdk2, and thus induced more incorporation of Bromodeoxyuridine (BrdU) in cultured cells indicating increased DNA synthesis. benzylaminopurine 30-33 cyclin dependent kinase 2 Homo sapiens 107-111 30342413-9 2018 The strongest AhR agonist activity was detected in B3-S, with 450 +- 20 mug BaP/L equivalency at 5 x exposure. benzylaminopurine 76-79 aryl hydrocarbon receptor Homo sapiens 14-17 29101605-12 2018 Hence, we concluded that in all the conditions, LDLR expression was found to be a translational event of its transcription factor, SREBP-2, by the induction of insulin, BaP and UV irradiation. benzylaminopurine 169-172 sterol regulatory element binding transcription factor 2 Homo sapiens 131-138 29499557-7 2018 The results indicate the ability of IL2 as cross-linker to enhance electrocatalytic activity and adsorption capacity for 6-BAP of IL-GR-MIP. benzylaminopurine 121-126 interleukin 2 Homo sapiens 36-39 29796946-5 2018 BA down-regulated most of the identified molecules in relation to GA3 and MS0 (control). benzylaminopurine 0-2 succinyl-CoA:glutarate-CoA transferase Homo sapiens 66-69 29796946-6 2018 The results showed that GA3 elicited synthesis of many phenols from different classes, and seemed to play a major role in the shikimate pathway in relation to BA. benzylaminopurine 159-161 succinyl-CoA:glutarate-CoA transferase Homo sapiens 24-27 29796946-7 2018 GA3 enhanced production of sesquiterpenoids, polyterpenoids, steroids and monoterpenoids compared to MS0 and BA, and also seemed to positively influence the MEP/DOXP and MVA pathways. benzylaminopurine 109-111 succinyl-CoA:glutarate-CoA transferase Homo sapiens 0-3 29909338-4 2018 Western blot analysis showed that BAP 23 markedly reduced the levels of Bcl-2 but increased the levels of cleaved caspase-3and Bax. benzylaminopurine 34-37 BCL2 apoptosis regulator Homo sapiens 72-77 29909338-4 2018 Western blot analysis showed that BAP 23 markedly reduced the levels of Bcl-2 but increased the levels of cleaved caspase-3and Bax. benzylaminopurine 34-37 BCL2 associated X, apoptosis regulator Homo sapiens 127-130 29909338-5 2018 Moreover, BAP 23 prominently inhibited LPS-induced activation of NF-kappaB in RAW264.7 cells as well as TNF-alpha-induced activation of NF-kappaB in HepG2 cells by blocking phosphorylation of inhibitor IkappaBalpha and p65. benzylaminopurine 10-13 NFKB inhibitor alpha Homo sapiens 202-214 29909338-5 2018 Moreover, BAP 23 prominently inhibited LPS-induced activation of NF-kappaB in RAW264.7 cells as well as TNF-alpha-induced activation of NF-kappaB in HepG2 cells by blocking phosphorylation of inhibitor IkappaBalpha and p65. benzylaminopurine 10-13 RELA proto-oncogene, NF-kB subunit Homo sapiens 219-222 29909338-6 2018 Consistent with these results, we found that BAP 23 prevented the nuclear translocation of NF-kappaB induced by LPS or TNF-alpha. benzylaminopurine 45-48 tumor necrosis factor Homo sapiens 119-128 29909338-7 2018 BAP 23 could reasonably bind to the active site of Bcl-2 protein and p65 which is proved by molecular docking modes. benzylaminopurine 0-3 BCL2 apoptosis regulator Homo sapiens 51-56 29909338-7 2018 BAP 23 could reasonably bind to the active site of Bcl-2 protein and p65 which is proved by molecular docking modes. benzylaminopurine 0-3 RELA proto-oncogene, NF-kB subunit Homo sapiens 69-72 29690626-8 2018 After the four-week intervention, postprandial FOX and the postprandial BAP/d-ROMs ratio were significantly higher in the CGA-HHQ(&minus;) group compared with the CGA-HHQ(+) group (4 &plusmn; 23 mg/min, group effect: p = 0.040; 0.27 &plusmn; 0.74, group effect: p = 0.007, respectively). benzylaminopurine 72-75 chromogranin A Homo sapiens 122-125 29673198-8 2018 Evaluation of survival signaling cascades showed that although the MEK-ERK and Akt pathways were activated in the presence of drugs, BaP was a stronger activator of the MEK-ERK and Akt pathways than the drugs. benzylaminopurine 133-136 mitogen-activated protein kinase kinase 7 Homo sapiens 169-172 29673198-8 2018 Evaluation of survival signaling cascades showed that although the MEK-ERK and Akt pathways were activated in the presence of drugs, BaP was a stronger activator of the MEK-ERK and Akt pathways than the drugs. benzylaminopurine 133-136 mitogen-activated protein kinase 1 Homo sapiens 173-176 29673198-8 2018 Evaluation of survival signaling cascades showed that although the MEK-ERK and Akt pathways were activated in the presence of drugs, BaP was a stronger activator of the MEK-ERK and Akt pathways than the drugs. benzylaminopurine 133-136 AKT serine/threonine kinase 1 Homo sapiens 181-184 29673198-9 2018 Conclusion: The present study suggest that BaP can reverse the effects of drugs on cancer cells via the activation of survival signaling pathways and upregulation of anti-apoptotic proteins such as Bcl-2 and Bcl-xL. benzylaminopurine 43-46 BCL2 apoptosis regulator Homo sapiens 198-203 29673198-9 2018 Conclusion: The present study suggest that BaP can reverse the effects of drugs on cancer cells via the activation of survival signaling pathways and upregulation of anti-apoptotic proteins such as Bcl-2 and Bcl-xL. benzylaminopurine 43-46 BCL2 like 1 Homo sapiens 208-214 29309894-5 2018 BaP exposure significantly increased expression of genes associated with oxidative stress, Cyp1a1, Sod1 and Sod2, while repressing Gpx1. benzylaminopurine 0-3 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 91-97 29409851-9 2018 Results indicated that most of the MdIPT and MdCKX, and MdPIN1 genes were upregulated by 6-BA and decapitation treatment, but inhibited by Lovastatin, a compound that effectively suppresses axillary bud outgrowth induced by decapitation. benzylaminopurine 89-93 peptidyl-prolyl cis-trans isomerase Pin1 Malus domestica 56-62 29309894-5 2018 BaP exposure significantly increased expression of genes associated with oxidative stress, Cyp1a1, Sod1 and Sod2, while repressing Gpx1. benzylaminopurine 0-3 superoxide dismutase 1 Homo sapiens 99-103 29309894-5 2018 BaP exposure significantly increased expression of genes associated with oxidative stress, Cyp1a1, Sod1 and Sod2, while repressing Gpx1. benzylaminopurine 0-3 superoxide dismutase 2 Homo sapiens 108-112 29309894-5 2018 BaP exposure significantly increased expression of genes associated with oxidative stress, Cyp1a1, Sod1 and Sod2, while repressing Gpx1. benzylaminopurine 0-3 glutathione peroxidase 1 Homo sapiens 131-135 28754838-0 2017 The chromatin remodeling BAP complex limits tumor-promoting activity of the Hippo pathway effector Yki to prevent neoplastic transformation in Drosophila epithelia. benzylaminopurine 25-28 yorkie Drosophila melanogaster 99-102 28801706-10 2017 Among the seven carcinogenic PAHs, BaP accounted for the majority of the potency and could potentially be used as a unique indicator of PAH toxicity. benzylaminopurine 35-38 phenylalanine hydroxylase Homo sapiens 29-32 28972453-10 2018 CONCLUSIONS: This study supports reduced eye contact as a phenotypic feature of the FMR1 premutation, which presents independent of social anxiety and the BAP. benzylaminopurine 155-158 fragile X messenger ribonucleoprotein 1 Homo sapiens 84-88 29238429-14 2018 The BAP/CTX ratio and PTH were significantly and inversely correlated at 3 months (r = -0.59, P = 0.01) and 6 months (r = -0.58, P < 0.01). benzylaminopurine 4-7 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 8-11 28754838-3 2017 Members of the BAP complex exhibit tumor suppressor activity in tissue overexpressing the Yorkie (Yki) proto-oncogene, but not in tissue overexpressing epidermal growth factor receptor (EGFR). benzylaminopurine 15-18 yorkie Drosophila melanogaster 90-96 28754838-3 2017 Members of the BAP complex exhibit tumor suppressor activity in tissue overexpressing the Yorkie (Yki) proto-oncogene, but not in tissue overexpressing epidermal growth factor receptor (EGFR). benzylaminopurine 15-18 yorkie Drosophila melanogaster 98-101 28754838-5 2017 However, we observed that depletion of BAP leads to ectopic expression of Yki targets both autonomously and non-autonomously, suggesting additional indirect effects. benzylaminopurine 39-42 yorkie Drosophila melanogaster 74-77 28754838-6 2017 We provide evidence that BAP complex depletion causes upregulation of the Wingless (Wg) and Decapentaplegic (Dpp) morphogens to promote tumor formation in cooperation with Yki. benzylaminopurine 25-28 yorkie Drosophila melanogaster 172-175 28577950-10 2017 d-ROMs and BAP test values were significantly higher in the high than in the low MTH1 expression group (p<0.05). benzylaminopurine 11-14 nudix hydrolase 1 Homo sapiens 81-85 28646624-6 2017 Higher BAP test values were found in patients expressing CD49d (P=.01) and with more advanced clinical stage (P=.004). benzylaminopurine 7-10 integrin subunit alpha 4 Homo sapiens 57-62 28860039-3 2017 We use the prokaryotic biotin ligase (BirA) to biotinylate the human leukocyte antigen (HLA)-A2 (A2) heavy chain (HC), which was engineered to contain a biotin acceptor peptide (BAP). benzylaminopurine 178-181 ATPase H+ transporting V0 subunit a2 Homo sapiens 93-95 28679143-12 2017 At KTx serum FGF-23 correlated only with phosphate (r=0.62, p=0.01) and PTH with BAP (r=0.49, p=0.04) but not with sclerostin. benzylaminopurine 81-84 fibroblast growth factor 23 Homo sapiens 13-19 28679143-12 2017 At KTx serum FGF-23 correlated only with phosphate (r=0.62, p=0.01) and PTH with BAP (r=0.49, p=0.04) but not with sclerostin. benzylaminopurine 81-84 parathyroid hormone Homo sapiens 72-75 28300668-3 2017 Aim of the study was to examine UGT1A regulation in response to Benzo[alpha]pyrene (BaP) to elucidate the potentially protective effects of coffee on BaP-induced oxidative stress and toxicity. benzylaminopurine 84-87 Ugt1a@ Mus musculus 32-37 28300668-3 2017 Aim of the study was to examine UGT1A regulation in response to Benzo[alpha]pyrene (BaP) to elucidate the potentially protective effects of coffee on BaP-induced oxidative stress and toxicity. benzylaminopurine 150-153 Ugt1a@ Mus musculus 32-37 28300668-5 2017 siRNA-mediated knockdown identified aryl hydrocarbon receptor (AhR) and nuclear factor erythroid2-related factor-2 (Nrf2) as mediators of BaP-induced UGT1A upregulation. benzylaminopurine 138-141 aryl-hydrocarbon receptor Mus musculus 36-61 28300668-5 2017 siRNA-mediated knockdown identified aryl hydrocarbon receptor (AhR) and nuclear factor erythroid2-related factor-2 (Nrf2) as mediators of BaP-induced UGT1A upregulation. benzylaminopurine 138-141 aryl-hydrocarbon receptor Mus musculus 63-66 28300668-5 2017 siRNA-mediated knockdown identified aryl hydrocarbon receptor (AhR) and nuclear factor erythroid2-related factor-2 (Nrf2) as mediators of BaP-induced UGT1A upregulation. benzylaminopurine 138-141 nuclear factor, erythroid derived 2, like 2 Mus musculus 72-114 28300668-5 2017 siRNA-mediated knockdown identified aryl hydrocarbon receptor (AhR) and nuclear factor erythroid2-related factor-2 (Nrf2) as mediators of BaP-induced UGT1A upregulation. benzylaminopurine 138-141 nuclear factor, erythroid derived 2, like 2 Mus musculus 116-120 28300668-5 2017 siRNA-mediated knockdown identified aryl hydrocarbon receptor (AhR) and nuclear factor erythroid2-related factor-2 (Nrf2) as mediators of BaP-induced UGT1A upregulation. benzylaminopurine 138-141 Ugt1a@ Mus musculus 150-155 28300668-9 2017 Coffee was demonstrated to inhibit BaP-induced production of oxidative stress by UGT1A activation, and is therefore an attractive candidate for chemoprotection in risk groups for HCC or other tumors. benzylaminopurine 35-38 Ugt1a@ Mus musculus 81-86 28323966-9 2017 Results: OC+BAP+ MCCs were severely reduced in acromegalic compared with control patients (0.17% +- 0.02% vs 1.00% +- 0.24%; P < 0.001), as were the total OC+ and BAP+ monocytic cells. benzylaminopurine 12-15 bone gamma-carboxyglutamate protein Homo sapiens 158-160 28428138-5 2017 We found that PXR activation could significantly inhibit BaP-induced DNA damage in the HepG2 cells as well as mouse hepatocytes. benzylaminopurine 57-60 nuclear receptor subfamily 1 group I member 2 Homo sapiens 14-17 28428138-6 2017 Using PXR-null and wild type mouse hepatocytes we showed that PXR activation by pregnenolone 16alpha-carbonitrile (PCN) significantly inhibited BaP-induced DNA damage and this protective effect was abolished in PXR-null hepatocytes. benzylaminopurine 144-147 nuclear receptor subfamily 1, group I, member 2 Mus musculus 62-65 28428138-6 2017 Using PXR-null and wild type mouse hepatocytes we showed that PXR activation by pregnenolone 16alpha-carbonitrile (PCN) significantly inhibited BaP-induced DNA damage and this protective effect was abolished in PXR-null hepatocytes. benzylaminopurine 144-147 nuclear receptor subfamily 1, group I, member 2 Mus musculus 62-65 28428138-7 2017 Mechanistically, PXR activation inhibited expression of AhR-target genes for CYP1A1, CYP1B1 and CYP1A2 that are required for BaP biotransformation in cultured liver cells, or in the livers of C57BL/6J mice. benzylaminopurine 125-128 nuclear receptor subfamily 1, group I, member 2 Mus musculus 17-20 28428138-7 2017 Mechanistically, PXR activation inhibited expression of AhR-target genes for CYP1A1, CYP1B1 and CYP1A2 that are required for BaP biotransformation in cultured liver cells, or in the livers of C57BL/6J mice. benzylaminopurine 125-128 aryl-hydrocarbon receptor Mus musculus 56-59 28428138-7 2017 Mechanistically, PXR activation inhibited expression of AhR-target genes for CYP1A1, CYP1B1 and CYP1A2 that are required for BaP biotransformation in cultured liver cells, or in the livers of C57BL/6J mice. benzylaminopurine 125-128 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 77-83 28428138-7 2017 Mechanistically, PXR activation inhibited expression of AhR-target genes for CYP1A1, CYP1B1 and CYP1A2 that are required for BaP biotransformation in cultured liver cells, or in the livers of C57BL/6J mice. benzylaminopurine 125-128 cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus 85-91 28428138-7 2017 Mechanistically, PXR activation inhibited expression of AhR-target genes for CYP1A1, CYP1B1 and CYP1A2 that are required for BaP biotransformation in cultured liver cells, or in the livers of C57BL/6J mice. benzylaminopurine 125-128 cytochrome P450, family 1, subfamily a, polypeptide 2 Mus musculus 96-102 28428138-10 2017 Taken together, our study has revealed a novel mechanism by which PXR protects liver cells from BaP-induced DNA damage through inhibiting the BaP biotransformation. benzylaminopurine 96-99 nuclear receptor subfamily 1 group I member 2 Homo sapiens 66-69 28428138-10 2017 Taken together, our study has revealed a novel mechanism by which PXR protects liver cells from BaP-induced DNA damage through inhibiting the BaP biotransformation. benzylaminopurine 142-145 nuclear receptor subfamily 1 group I member 2 Homo sapiens 66-69 28147482-0 2017 Ionic Liquid-Hybrid Molecularly Imprinted Material-Filter Solid-Phase Extraction Coupled with HPLC for Determination of 6-Benzyladenine and 4-Chlorophenoxyacetic Acid in Bean Sprouts. benzylaminopurine 120-135 brain expressed associated with NEDD4 1 Homo sapiens 170-174 28426078-4 2017 Specifically, we demonstrate that the SNM-based intravascular BAP with ~10 and ~40 nm pore sized membranes support high islet viability (>60%) and functionality (<15 minute insulin response to glucose stimulation) at clinically relevant islet densities (5700 and 11 400 IE per cm2) under convection in vitro. benzylaminopurine 62-65 insulin Homo sapiens 179-186 28494841-3 2017 Quercetin did not influence CYP1A1 in untreated rats but inhibited BaP-mediated CYP1A induction on the transcriptional level decreasing positive input (AhR functional activity) and increasing negative input (AhRR/ARNT expression and Oct-1 and C/EBP functional activities). benzylaminopurine 67-70 aryl hydrocarbon receptor Rattus norvegicus 152-155 28494841-3 2017 Quercetin did not influence CYP1A1 in untreated rats but inhibited BaP-mediated CYP1A induction on the transcriptional level decreasing positive input (AhR functional activity) and increasing negative input (AhRR/ARNT expression and Oct-1 and C/EBP functional activities). benzylaminopurine 67-70 aryl-hydrocarbon receptor repressor Rattus norvegicus 208-212 28494841-3 2017 Quercetin did not influence CYP1A1 in untreated rats but inhibited BaP-mediated CYP1A induction on the transcriptional level decreasing positive input (AhR functional activity) and increasing negative input (AhRR/ARNT expression and Oct-1 and C/EBP functional activities). benzylaminopurine 67-70 aryl hydrocarbon receptor nuclear translocator Rattus norvegicus 213-217 28494841-3 2017 Quercetin did not influence CYP1A1 in untreated rats but inhibited BaP-mediated CYP1A induction on the transcriptional level decreasing positive input (AhR functional activity) and increasing negative input (AhRR/ARNT expression and Oct-1 and C/EBP functional activities). benzylaminopurine 67-70 solute carrier family 22 member 1 Rattus norvegicus 233-238 28494841-3 2017 Quercetin did not influence CYP1A1 in untreated rats but inhibited BaP-mediated CYP1A induction on the transcriptional level decreasing positive input (AhR functional activity) and increasing negative input (AhRR/ARNT expression and Oct-1 and C/EBP functional activities). benzylaminopurine 67-70 CCAAT/enhancer binding protein gamma Rattus norvegicus 243-248 28193466-6 2017 The results showed that the concentrations of BaP in 3 out of 11 samples were higher than the legal limit (2.0mug/kg, Commission Regulation 835/2011a), the sum of 8 heavy PAHs (BaA, CHR, BbF, BkF, BaP, IcP, DaA, BgP) in 11 samples was between 3.03mug/kg and 229.5mug/kg. benzylaminopurine 46-49 chromate resistance; sulfate transport Homo sapiens 182-185 28193466-6 2017 The results showed that the concentrations of BaP in 3 out of 11 samples were higher than the legal limit (2.0mug/kg, Commission Regulation 835/2011a), the sum of 8 heavy PAHs (BaA, CHR, BbF, BkF, BaP, IcP, DaA, BgP) in 11 samples was between 3.03mug/kg and 229.5mug/kg. benzylaminopurine 46-49 CEA cell adhesion molecule 1 Homo sapiens 212-215 28147482-1 2017 A new method involving ionic liquid-hybrid molecularly imprinted material-filter solid-phase extraction coupled to high-performance liquid chromatography (IL-HIM-FSPE-HPLC) was developed for the simultaneous isolation and determination of 6-benzyladenine (6-BA) and 4-chlorophenoxyacetic acid (4-CPA) in bean sprouts. benzylaminopurine 239-254 brain expressed associated with NEDD4 1 Homo sapiens 304-308 28147482-1 2017 A new method involving ionic liquid-hybrid molecularly imprinted material-filter solid-phase extraction coupled to high-performance liquid chromatography (IL-HIM-FSPE-HPLC) was developed for the simultaneous isolation and determination of 6-benzyladenine (6-BA) and 4-chlorophenoxyacetic acid (4-CPA) in bean sprouts. benzylaminopurine 256-260 carboxypeptidase A1 Homo sapiens 296-299 28147482-1 2017 A new method involving ionic liquid-hybrid molecularly imprinted material-filter solid-phase extraction coupled to high-performance liquid chromatography (IL-HIM-FSPE-HPLC) was developed for the simultaneous isolation and determination of 6-benzyladenine (6-BA) and 4-chlorophenoxyacetic acid (4-CPA) in bean sprouts. benzylaminopurine 256-260 brain expressed associated with NEDD4 1 Homo sapiens 304-308 28147482-4 2017 This method combines the advantages of ionic liquids, hybrid materials, and molecularly imprinted polymers and was successfully applied to determine 6-BA and 4-CPA in bean sprouts. benzylaminopurine 149-153 brain expressed associated with NEDD4 1 Homo sapiens 167-171 28147482-1 2017 A new method involving ionic liquid-hybrid molecularly imprinted material-filter solid-phase extraction coupled to high-performance liquid chromatography (IL-HIM-FSPE-HPLC) was developed for the simultaneous isolation and determination of 6-benzyladenine (6-BA) and 4-chlorophenoxyacetic acid (4-CPA) in bean sprouts. benzylaminopurine 239-254 carboxypeptidase A1 Homo sapiens 296-299 27863410-6 2016 Significantly increased expression of STIM1 mRNA and protein was observed in 16HBE-benzo(a)pyrene (BaP) cells and in BaP-treated mice lung tissues compared with 16HBE-control cells and the control group, respectively. benzylaminopurine 99-102 stromal interaction molecule 1 Mus musculus 38-43 27863410-6 2016 Significantly increased expression of STIM1 mRNA and protein was observed in 16HBE-benzo(a)pyrene (BaP) cells and in BaP-treated mice lung tissues compared with 16HBE-control cells and the control group, respectively. benzylaminopurine 117-120 stromal interaction molecule 1 Mus musculus 38-43 27473418-6 2016 The method showed good linearity for the determination of BaP in the concentration range of 0.5-50 ng mL-1 with a regression coefficient (R2) of 0.9987. benzylaminopurine 58-61 L1 cell adhesion molecule Mus musculus 102-106 27840869-5 2016 The fusion protein comprised of ELP-D and Nluc-BAP (ELP-D-Nluc-BAP) was found to form nanoparticles with Nluc and BAP displayed multivalently on their surfaces. benzylaminopurine 47-50 nuclear receptor subfamily 5 group A member 1 Homo sapiens 52-55 27473418-7 2016 The limit of detection and limit of quantification for BaP were obtained to be 0.12 and 0.41 ng mL-1, respectively. benzylaminopurine 55-58 L1 cell adhesion molecule Mus musculus 96-100 27493727-7 2016 Finally, we show that the PC activity of K562 cells exclusively fuels the ROS-induced decarboxylation of oxaloacetate to malonate in response to BaP treatment; resulting in further Krebs cycle disruption via depletion of oxaloacetate and malonate-mediated inhibition of succinate dehydrogenase (SDH) resulting in a twofold reduction of fumarate. benzylaminopurine 145-148 pyruvate carboxylase Homo sapiens 26-28 27577850-4 2016 Here we show that treatment with TGFbeta pathway inhibitor SB431542 together with ascorbic acid and EGF were required to promote hiPSCs-BAP differentiation at a level similar to adult-BAP differentiation. benzylaminopurine 136-139 transforming growth factor beta 1 Homo sapiens 33-40 27577850-4 2016 Here we show that treatment with TGFbeta pathway inhibitor SB431542 together with ascorbic acid and EGF were required to promote hiPSCs-BAP differentiation at a level similar to adult-BAP differentiation. benzylaminopurine 184-187 transforming growth factor beta 1 Homo sapiens 33-40 27645097-3 2016 Decapitation or the application of 6-benzylaminopurine (BAP) can initially promote axillary shoots, during which SlARF2a expression is significantly reduced. benzylaminopurine 35-54 auxin response factor 2A Solanum lycopersicum 113-120 27645097-3 2016 Decapitation or the application of 6-benzylaminopurine (BAP) can initially promote axillary shoots, during which SlARF2a expression is significantly reduced. benzylaminopurine 56-59 auxin response factor 2A Solanum lycopersicum 113-120 27493727-7 2016 Finally, we show that the PC activity of K562 cells exclusively fuels the ROS-induced decarboxylation of oxaloacetate to malonate in response to BaP treatment; resulting in further Krebs cycle disruption via depletion of oxaloacetate and malonate-mediated inhibition of succinate dehydrogenase (SDH) resulting in a twofold reduction of fumarate. benzylaminopurine 145-148 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 270-293 27493727-7 2016 Finally, we show that the PC activity of K562 cells exclusively fuels the ROS-induced decarboxylation of oxaloacetate to malonate in response to BaP treatment; resulting in further Krebs cycle disruption via depletion of oxaloacetate and malonate-mediated inhibition of succinate dehydrogenase (SDH) resulting in a twofold reduction of fumarate. benzylaminopurine 145-148 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 295-298 27493727-9 2016 Moreover, our studies indicate that the PC activity in cancer cells can be exploited as an Achilles heel by using treatments, such as BaP, that elevate ROS production. benzylaminopurine 134-137 pyruvate carboxylase Homo sapiens 40-42 25913286-7 2016 Further, docking of BaP and chrysene with the TiO2 NP bound AHR complex revealed their strong adsorption on TiO2 NP itself, and not on their original binding site (at AHR). benzylaminopurine 20-23 aryl hydrocarbon receptor Homo sapiens 60-63 27452439-3 2016 We hypothesized that exposure of human fetoplacental endothelial cells (ECs) to the PAH benzo[a]yrene (BaP) would result in up-regulation of cyclooxygenase-2 (PTGS2) and preferential production of vasoconstrictive prostanoids via activation of the aryl hydrocarbon receptor (AHR) pathway. benzylaminopurine 103-106 phenylalanine hydroxylase Homo sapiens 84-87 27452439-3 2016 We hypothesized that exposure of human fetoplacental endothelial cells (ECs) to the PAH benzo[a]yrene (BaP) would result in up-regulation of cyclooxygenase-2 (PTGS2) and preferential production of vasoconstrictive prostanoids via activation of the aryl hydrocarbon receptor (AHR) pathway. benzylaminopurine 103-106 prostaglandin-endoperoxide synthase 2 Homo sapiens 141-157 27452439-3 2016 We hypothesized that exposure of human fetoplacental endothelial cells (ECs) to the PAH benzo[a]yrene (BaP) would result in up-regulation of cyclooxygenase-2 (PTGS2) and preferential production of vasoconstrictive prostanoids via activation of the aryl hydrocarbon receptor (AHR) pathway. benzylaminopurine 103-106 prostaglandin-endoperoxide synthase 2 Homo sapiens 159-164 27452439-3 2016 We hypothesized that exposure of human fetoplacental endothelial cells (ECs) to the PAH benzo[a]yrene (BaP) would result in up-regulation of cyclooxygenase-2 (PTGS2) and preferential production of vasoconstrictive prostanoids via activation of the aryl hydrocarbon receptor (AHR) pathway. benzylaminopurine 103-106 aryl hydrocarbon receptor Homo sapiens 248-273 27452439-3 2016 We hypothesized that exposure of human fetoplacental endothelial cells (ECs) to the PAH benzo[a]yrene (BaP) would result in up-regulation of cyclooxygenase-2 (PTGS2) and preferential production of vasoconstrictive prostanoids via activation of the aryl hydrocarbon receptor (AHR) pathway. benzylaminopurine 103-106 aryl hydrocarbon receptor Homo sapiens 275-278 27452439-7 2016 RESULTS: BaP induced PTGS2 expression (p < 0.05) and production of the stable metabolite of prostacyclin (p = 0.001) in fetoplacental ECs without affecting thromboxane. benzylaminopurine 9-12 prostaglandin-endoperoxide synthase 2 Homo sapiens 21-26 27452439-11 2016 DISCUSSION: BaP-mediated AHR activation results in induction of PTGS2 expression and enhanced production of prostacyclin metabolite. benzylaminopurine 12-15 aryl hydrocarbon receptor Homo sapiens 25-28 27452439-11 2016 DISCUSSION: BaP-mediated AHR activation results in induction of PTGS2 expression and enhanced production of prostacyclin metabolite. benzylaminopurine 12-15 prostaglandin-endoperoxide synthase 2 Homo sapiens 64-69 27452439-12 2016 Despite an increase in this vasodilatory and pro-angiogenic prostanoid, BaP exposure also impairs EC migration and angiogenesis through AHR. benzylaminopurine 72-75 aryl hydrocarbon receptor Homo sapiens 136-139 27051599-7 2016 RESULTS: ERalpha mRNA levels in PBCs had a negative correlation with age and a positive correlation with estrogen and BAP in the osteopenia and osteoporosis groups, but not in the control group. benzylaminopurine 118-121 estrogen receptor 1 Homo sapiens 9-16 27142370-8 2016 Significant correlation between serum TRAcP 5b and BAP activities was noted (r = 0.60, p < 0.001). benzylaminopurine 51-54 acid phosphatase 5, tartrate resistant Homo sapiens 38-46 27408764-11 2016 In conclusion, GDF11 is an independent negative predictor of BMD and correlates with a biomarker of bone formation, BAP, in postmenopausal Chinese women. benzylaminopurine 116-119 growth differentiation factor 11 Homo sapiens 15-20 27125095-5 2016 BAP-invasive carcinoma NST: left breast-pT2mN3a G2, right breast--pT3mN3a G2, IHC-RE = 90%, RP =70% HER2neu = 2 +, Ki67 = 50%. benzylaminopurine 0-3 erb-b2 receptor tyrosine kinase 2 Homo sapiens 100-107 26506085-11 2016 As for circulating osteoprogenitors, we found a significant reduction of CD34(+) BAP(+) (P < 0.05) and CD34(+) OCN(+) BAP(+) (P < 0.05) cells. benzylaminopurine 81-84 CD34 molecule Homo sapiens 73-77 26506085-11 2016 As for circulating osteoprogenitors, we found a significant reduction of CD34(+) BAP(+) (P < 0.05) and CD34(+) OCN(+) BAP(+) (P < 0.05) cells. benzylaminopurine 121-124 CD34 molecule Homo sapiens 106-110 26325612-4 2016 The BAP is an extremely complex delivery system for insulin. benzylaminopurine 4-7 insulin Homo sapiens 52-59 26706318-5 2016 Most of the derivatives did not trigger cytokinin signaling via the AHK3 and AHK4 receptors from Arabidopsis thaliana in the bacterial assay, but some of them specifically activated the ZmHK1 receptor from Zea mays and were also more active than the aromatic cytokinin BAP in an ARR5::GUS cytokinin bioassay using transgenic Arabidopsis plants. benzylaminopurine 269-272 histidine kinase 1 Zea mays 186-191 26277277-5 2015 The ratio of IgG1/IgG2c and profile of IL-4/IFN-gamma in OMV (PagL)+Bap (1-487aa) formulation shows the humoral and cellular immune responses have been induced robustly and have created a full protection against A. baumannii ATCC 19606 and MDR AB-44 strains. benzylaminopurine 68-71 interleukin 4 Mus musculus 39-43 26409108-3 2015 BAP had higher formation reactivity of halogenated carbonaceous and nitrogenous DBPs including trihalomethanes, haloketones, haloacetonitriles and trichloronitromethane due to their higher percentage of large molecular weight (MW) materials and humic substances compared with UAP. benzylaminopurine 0-3 ubiquitin associated protein 1 Homo sapiens 276-279 26338362-2 2015 The crystal structure of N-benzyl-9H-purin-6-amine 1 in complex with ERK2 elucidated its hinge-binding mode. benzylaminopurine 25-50 mitogen-activated protein kinase 1 Homo sapiens 69-73 26291679-6 2015 Results demonstrated that expressions of SKN-1 and GCS-1 were altered significantly following BaP exposure (P<0.05). benzylaminopurine 94-97 BZIP domain-containing protein;Protein skinhead-1 Caenorhabditis elegans 41-46 26291679-6 2015 Results demonstrated that expressions of SKN-1 and GCS-1 were altered significantly following BaP exposure (P<0.05). benzylaminopurine 94-97 Glutamate--cysteine ligase Caenorhabditis elegans 51-56 26291679-12 2015 The expressional response of GCS-1 to BaP exposure might be independent of the regulation of SKN-1 in C. elegans. benzylaminopurine 38-41 Glutamate--cysteine ligase Caenorhabditis elegans 29-34 26291679-13 2015 The microRNAs might be involved in the regulations of SKN-1 and GCS-1 expression following BaP exposure in C. elegans. benzylaminopurine 91-94 BZIP domain-containing protein;Protein skinhead-1 Caenorhabditis elegans 54-59 26291679-13 2015 The microRNAs might be involved in the regulations of SKN-1 and GCS-1 expression following BaP exposure in C. elegans. benzylaminopurine 91-94 Glutamate--cysteine ligase Caenorhabditis elegans 64-69 26862562-7 2016 Positively leaf initiation and formation was better in the concentration of IBA 1-3.5 mg/l+BAP 1.0-2.0 mg/l combination. benzylaminopurine 91-94 allograft inflammatory factor 1 Homo sapiens 76-81 26517840-2 2015 Embryogenic tissue that proliferated at lower concentrations (3.6 muM and 2.5 muM) of 6-benzylaminopurine (6-BAP) were more productive, and generated 113 +- 6 and 89 +- 3 mature embryos per 100 mg embryogenic tissue, respectively. benzylaminopurine 86-105 latexin Homo sapiens 78-81 26517840-2 2015 Embryogenic tissue that proliferated at lower concentrations (3.6 muM and 2.5 muM) of 6-benzylaminopurine (6-BAP) were more productive, and generated 113 +- 6 and 89 +- 3 mature embryos per 100 mg embryogenic tissue, respectively. benzylaminopurine 107-112 latexin Homo sapiens 78-81 26277277-5 2015 The ratio of IgG1/IgG2c and profile of IL-4/IFN-gamma in OMV (PagL)+Bap (1-487aa) formulation shows the humoral and cellular immune responses have been induced robustly and have created a full protection against A. baumannii ATCC 19606 and MDR AB-44 strains. benzylaminopurine 68-71 interferon gamma Mus musculus 44-53 25510858-8 2015 Chronic alcohol exposure increased bAP-evoked Ca(2+) transients in the distal apical dendrites of CA1 pyramidal neurons. benzylaminopurine 35-38 carbonic anhydrase 1 Homo sapiens 98-101 25896784-5 2015 Between 10 and 21 days of age, the BAP was induced coincident with morphologic remodeling of ING and marked changes in expression of neural development genes (e.g., Akap 12 and Ngfr). benzylaminopurine 35-38 A kinase (PRKA) anchor protein (gravin) 12 Mus musculus 165-172 25896784-5 2015 Between 10 and 21 days of age, the BAP was induced coincident with morphologic remodeling of ING and marked changes in expression of neural development genes (e.g., Akap 12 and Ngfr). benzylaminopurine 35-38 nerve growth factor receptor (TNFR superfamily, member 16) Mus musculus 177-181 26098891-9 2015 Induction, but not expression, of bAP-Ca2+ transient enhancement is a spine-specific function of the RyR. benzylaminopurine 34-37 ryanodine receptor 1 Homo sapiens 101-104 25510858-10 2015 CONCLUSIONS: These data suggest that chronic alcohol-induced decreases in Kv4.2 channel function possibly mediated by a downregulation of KChIP3 drive the elevated bAP-associated Ca(2+) transients in distal apical dendrites. benzylaminopurine 164-167 potassium voltage-gated channel subfamily D member 2 Homo sapiens 74-79 25510858-10 2015 CONCLUSIONS: These data suggest that chronic alcohol-induced decreases in Kv4.2 channel function possibly mediated by a downregulation of KChIP3 drive the elevated bAP-associated Ca(2+) transients in distal apical dendrites. benzylaminopurine 164-167 potassium voltage-gated channel interacting protein 3 Homo sapiens 138-144 25823926-2 2015 The bionic airway chip culture data showed that macrophages promoted BaP-induced malignant transformation of human bronchial epithelial cells, which was mediated by nuclear factor (NF)-kappaB and STAT3 pathways to induce cell proliferation, colony formation in chip culture, and tumorigenicity in nude mice. benzylaminopurine 69-72 signal transducer and activator of transcription 3 Homo sapiens 196-201 25816607-2 2014 It was found that BAP regulated photosynthetic pigment, hydrogen peroxide content and activity of antioxidant enzymes, namely superoxide dismutase, ascorbate peroxidase and catalase under high-temperature conditions. benzylaminopurine 18-21 peroxidase-like Triticum aestivum 158-168 25537148-10 2014 In addition to the induction of cell apoptosis, we also found that the BAP of GFII could induce cell autophagy by inhibiting of PI3K/Akt/mTOR signaling pathway, and then suppress the breast cancer cell growth. benzylaminopurine 71-74 AKT serine/threonine kinase 1 Homo sapiens 133-136 25537148-10 2014 In addition to the induction of cell apoptosis, we also found that the BAP of GFII could induce cell autophagy by inhibiting of PI3K/Akt/mTOR signaling pathway, and then suppress the breast cancer cell growth. benzylaminopurine 71-74 mechanistic target of rapamycin kinase Homo sapiens 137-141 25412620-5 2015 Furthermore, AHR2 knockdown prevents the toxicity of BaP + FL mixture. benzylaminopurine 53-56 aryl hydrocarbon receptor 2 Danio rerio 13-17 25412620-9 2015 Data show AHR2-dependent BaP + FL effects on expression of genes involved in protein biosynthesis and neuronal development in addition to signaling molecules and their associated molecular pathways. benzylaminopurine 25-28 aryl hydrocarbon receptor 2 Danio rerio 10-14 25447797-1 2015 Mice deficient in cholesterol 7alpha-hydroxylase (Cyp7a1) have a diminished bile acid pool (BAP) and therefore represent a useful model for investigating the metabolic effects of restoring the pool with a specific BA. benzylaminopurine 92-95 cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus 18-48 25447797-1 2015 Mice deficient in cholesterol 7alpha-hydroxylase (Cyp7a1) have a diminished bile acid pool (BAP) and therefore represent a useful model for investigating the metabolic effects of restoring the pool with a specific BA. benzylaminopurine 92-95 cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus 50-56 25447797-2 2015 Previously we carried out such studies in Cyp7a1(-/-) mice fed physiological levels of cholic acid (CA) and achieved BAP restoration, along with an increased CA enrichment, at a dietary level of just 0.03% (w/w). benzylaminopurine 117-120 cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus 42-48 25447797-3 2015 Here we demonstrate that in Cyp7a1(-/-) mice fed chenodeoxycholic acid (CDCA) at a level of 0.06% (w/w), the BAP was restored to normal size and became substantially enriched with muricholic acid (MCA) (>70%), leaving the combined contribution of CA and CDCA to be <15%. benzylaminopurine 109-112 cytochrome P450, family 7, subfamily a, polypeptide 1 Mus musculus 28-34 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 0-3 caseinolytic mitochondrial matrix peptidase chaperone subunit B Homo sapiens 21-25 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 0-3 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 40-44 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 0-3 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 109-113 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 89-92 caseinolytic mitochondrial matrix peptidase chaperone subunit B Homo sapiens 21-25 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 89-92 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 40-44 25288401-5 2014 BAP is an engineered ClpB that can bind ClpP proteolytic chamber; substrates threaded by BAP are degraded by ClpP. benzylaminopurine 89-92 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 109-113 25234616-9 2014 The immunomodulatory effects of BAP were confirmed by lower levels of IL-1beta, IL-8, and a lower WBC count in the supplemented group in comparison with the control group. benzylaminopurine 32-35 interleukin 1 beta Homo sapiens 70-78 25234616-9 2014 The immunomodulatory effects of BAP were confirmed by lower levels of IL-1beta, IL-8, and a lower WBC count in the supplemented group in comparison with the control group. benzylaminopurine 32-35 C-X-C motif chemokine ligand 8 Homo sapiens 80-84 25234616-11 2014 In vitro, BAP suppressed mRNA expression of mRNA for IL-10 and all pro-inflammatory cytokines tested. benzylaminopurine 10-13 interleukin 10 Homo sapiens 53-58 25234616-14 2014 Further dose- and time-dependent suppression of the activated caspase 1 and pPKCepsilon was detected in macrophages when treated with BAP. benzylaminopurine 134-137 caspase 1 Homo sapiens 62-71 25215666-5 2014 BaP and other PAHs are known to enter the cell via aromatic hydrocarbon receptor (AHR). benzylaminopurine 0-3 aryl hydrocarbon receptor Homo sapiens 82-85 25215666-6 2014 TiO2 NP showed a much higher docking score with AHR (12074) as compared to the docking score of BaP with AHR (4600). benzylaminopurine 96-99 aryl hydrocarbon receptor Homo sapiens 105-108 25215666-7 2014 This indicates a preferential binding of TiO2 NP with the AHR, in case if both the TiO2 NP and BaP are present. benzylaminopurine 95-98 aryl hydrocarbon receptor Homo sapiens 58-61 25215666-8 2014 Further, we have done the docking of BaP with the TiO2 NP bound AHR-complex (score 4710), and observed that BaP showed strong adsorption on TiO2 NP itself, and not at its original binding site (at AHR). benzylaminopurine 37-40 aryl hydrocarbon receptor Homo sapiens 64-67 25215666-8 2014 Further, we have done the docking of BaP with the TiO2 NP bound AHR-complex (score 4710), and observed that BaP showed strong adsorption on TiO2 NP itself, and not at its original binding site (at AHR). benzylaminopurine 108-111 aryl hydrocarbon receptor Homo sapiens 64-67 25215666-8 2014 Further, we have done the docking of BaP with the TiO2 NP bound AHR-complex (score 4710), and observed that BaP showed strong adsorption on TiO2 NP itself, and not at its original binding site (at AHR). benzylaminopurine 108-111 aryl hydrocarbon receptor Homo sapiens 197-200 25215666-9 2014 TiO2 NPs thereby prevent the entry of BaP in to the cell via AHR and hence protect cells against the deleterious effects induced by BaP. benzylaminopurine 38-41 aryl hydrocarbon receptor Homo sapiens 61-64 25816607-2 2014 It was found that BAP regulated photosynthetic pigment, hydrogen peroxide content and activity of antioxidant enzymes, namely superoxide dismutase, ascorbate peroxidase and catalase under high-temperature conditions. benzylaminopurine 18-21 catalase-1 Triticum aestivum 173-181 25068272-6 2014 There are two Drosophila SWI/SNF complexes: the Brm-associated protein (BAP) complex and the polybromo-containing BAP (PBAP) complex. benzylaminopurine 72-75 sans fille Drosophila melanogaster 29-32 25068272-6 2014 There are two Drosophila SWI/SNF complexes: the Brm-associated protein (BAP) complex and the polybromo-containing BAP (PBAP) complex. benzylaminopurine 72-75 brahma Drosophila melanogaster 48-51 24860582-7 2014 Indeed, not only the cytokinin-response TCS::GFP marker, but also the auxin efflux carrier PIN1 (PIN1::PIN1:GFP) were both affected in BAP-induced valveless gynoecia, suggesting that the BAP treatment producing the morphological changes has an impact on both in the response pattern to cytokinin and on auxin transport. benzylaminopurine 135-138 Auxin efflux carrier family protein Arabidopsis thaliana 91-95 24860582-7 2014 Indeed, not only the cytokinin-response TCS::GFP marker, but also the auxin efflux carrier PIN1 (PIN1::PIN1:GFP) were both affected in BAP-induced valveless gynoecia, suggesting that the BAP treatment producing the morphological changes has an impact on both in the response pattern to cytokinin and on auxin transport. benzylaminopurine 135-138 Auxin efflux carrier family protein Arabidopsis thaliana 97-101 24860582-7 2014 Indeed, not only the cytokinin-response TCS::GFP marker, but also the auxin efflux carrier PIN1 (PIN1::PIN1:GFP) were both affected in BAP-induced valveless gynoecia, suggesting that the BAP treatment producing the morphological changes has an impact on both in the response pattern to cytokinin and on auxin transport. benzylaminopurine 135-138 Auxin efflux carrier family protein Arabidopsis thaliana 97-101 24584156-1 2014 A series of gold(III) complexes involving differently substituted derivatives of a plant hormone N6-benzyladenine (HL1-5) is reported. benzylaminopurine 97-113 intelectin 1 Homo sapiens 115-118 24843029-4 2014 We obtained electron microscopy (EM) structures of the BAP variant of ClpB that binds the protease ClpP, clearly revealing MD density on the surface of the ClpB ring. benzylaminopurine 55-58 caseinolytic mitochondrial matrix peptidase chaperone subunit B Homo sapiens 70-74 24843029-4 2014 We obtained electron microscopy (EM) structures of the BAP variant of ClpB that binds the protease ClpP, clearly revealing MD density on the surface of the ClpB ring. benzylaminopurine 55-58 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 99-103 24843029-4 2014 We obtained electron microscopy (EM) structures of the BAP variant of ClpB that binds the protease ClpP, clearly revealing MD density on the surface of the ClpB ring. benzylaminopurine 55-58 caseinolytic mitochondrial matrix peptidase chaperone subunit B Homo sapiens 156-160 24412785-0 2014 Specific binding and inhibition of 6-benzylaminopurine to catalase: multiple spectroscopic methods combined with molecular docking study. benzylaminopurine 35-54 catalase Homo sapiens 58-66 24412785-3 2014 The fluorescence quenching of beef liver catalase (BLC) by 6-BA is due to the formation of 6-BA-BLC complex. benzylaminopurine 59-63 catalase Homo sapiens 41-49 24412785-3 2014 The fluorescence quenching of beef liver catalase (BLC) by 6-BA is due to the formation of 6-BA-BLC complex. benzylaminopurine 91-95 catalase Homo sapiens 41-49 23588262-5 2014 BAP score was calculated based on a point system in which 1 point was assigned for baPWV above the median value of 1670 cm/s, ABI < 0.9 or >= 1.3 in either leg and bPEP/bET > 0.38. benzylaminopurine 0-3 delta/notch like EGF repeat containing Homo sapiens 175-178 24432373-4 2013 In this study, to construct an aptamer-modified Ad5, we first genetically modified the HVR5 of Ad hexon by biotin acceptor peptide (BAP), which would be metabolically biotinylated during production in HEK293 cells, and then attached the biotin labeled aptamer to the modified Ad through avidin-biotin binding. benzylaminopurine 132-135 Alzheimer disease, familial, type 5 Homo sapiens 48-51 24550111-8 2014 We also identified that the BAP chromatin-remodeling complex probably functions cooperatively with Erm to restrict the developmental potential of immature INPs. benzylaminopurine 28-31 earmuff Drosophila melanogaster 99-102 24550111-9 2014 Together, these data led us to conclude that the Erm-BAP-dependent mechanism stably restricts the developmental potential of immature INPs by attenuating their genomic responses to stem cell self-renewal factors. benzylaminopurine 53-56 earmuff Drosophila melanogaster 49-52 24152296-6 2014 The present study showed that OPG and TGF-beta2 had positive correlation with BAP, OC, uNTX, uCTX and uDPD, while TGF-beta1 showed negative correlation with BAP, OC, sCTX, uNTX and uCTX, and most of the coefficients of partial correlation remained significant after adjustments for age and body mass index (BMI). benzylaminopurine 78-81 TNF receptor superfamily member 11b Homo sapiens 30-33 24152296-6 2014 The present study showed that OPG and TGF-beta2 had positive correlation with BAP, OC, uNTX, uCTX and uDPD, while TGF-beta1 showed negative correlation with BAP, OC, sCTX, uNTX and uCTX, and most of the coefficients of partial correlation remained significant after adjustments for age and body mass index (BMI). benzylaminopurine 78-81 transforming growth factor beta 2 Homo sapiens 38-47 23830844-11 2013 Following multilinear regression analysis and adjustment for all significant co-variables, only eGFR, BAP and 25 (OH)vitamin remained significantly associated with intact PTH and biointact PTH (1-84). benzylaminopurine 102-105 parathyroid hormone Homo sapiens 189-192 23707232-9 2013 BIOLOGICAL SIGNIFICANCE: Transgenic broccoli harboring senescence-associated-gene (SAG) promoter-triggered isopentenyltransferase (ipt), which encodes the key enzyme for cytokinin (CK) synthesis and N(6)-benzylaminopurine (BA) CK treated broccoli both showed retardation of postharvest senescence during storage. benzylaminopurine 199-221 tRNA isopentenyltransferase 1 Homo sapiens 107-129 23707232-9 2013 BIOLOGICAL SIGNIFICANCE: Transgenic broccoli harboring senescence-associated-gene (SAG) promoter-triggered isopentenyltransferase (ipt), which encodes the key enzyme for cytokinin (CK) synthesis and N(6)-benzylaminopurine (BA) CK treated broccoli both showed retardation of postharvest senescence during storage. benzylaminopurine 199-221 tRNA isopentenyltransferase 1 Homo sapiens 131-134 23707232-9 2013 BIOLOGICAL SIGNIFICANCE: Transgenic broccoli harboring senescence-associated-gene (SAG) promoter-triggered isopentenyltransferase (ipt), which encodes the key enzyme for cytokinin (CK) synthesis and N(6)-benzylaminopurine (BA) CK treated broccoli both showed retardation of postharvest senescence during storage. benzylaminopurine 223-225 tRNA isopentenyltransferase 1 Homo sapiens 107-129 23707232-9 2013 BIOLOGICAL SIGNIFICANCE: Transgenic broccoli harboring senescence-associated-gene (SAG) promoter-triggered isopentenyltransferase (ipt), which encodes the key enzyme for cytokinin (CK) synthesis and N(6)-benzylaminopurine (BA) CK treated broccoli both showed retardation of postharvest senescence during storage. benzylaminopurine 223-225 tRNA isopentenyltransferase 1 Homo sapiens 131-134 23981714-7 2013 These results indicate that LTP-IE is mediated by the internalization of Kv1.2 channels from the distal regions of apical dendrites, which is triggered by bAP-induced dendritic Ca(2+) signalling and the consequent activation of PTK. benzylaminopurine 155-158 potassium voltage-gated channel, shaker-related subfamily, member 2 Mus musculus 73-78 23830844-12 2013 The strength of association was stronger between BAP and biointact PTH (1-84) (biointact PTH (1-84): p=0.007, intact PTH: p=0.01). benzylaminopurine 49-52 parathyroid hormone Homo sapiens 67-70 23830844-12 2013 The strength of association was stronger between BAP and biointact PTH (1-84) (biointact PTH (1-84): p=0.007, intact PTH: p=0.01). benzylaminopurine 49-52 parathyroid hormone Homo sapiens 89-92 23830844-12 2013 The strength of association was stronger between BAP and biointact PTH (1-84) (biointact PTH (1-84): p=0.007, intact PTH: p=0.01). benzylaminopurine 49-52 parathyroid hormone Homo sapiens 89-92 23649227-4 2013 Therefore, the possible involvement of alternative oxidase (AOX) in cell death process induced by BA and [9R]BA was studied. benzylaminopurine 98-100 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 39-58 23649227-4 2013 Therefore, the possible involvement of alternative oxidase (AOX) in cell death process induced by BA and [9R]BA was studied. benzylaminopurine 98-100 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 60-63 23649227-4 2013 Therefore, the possible involvement of alternative oxidase (AOX) in cell death process induced by BA and [9R]BA was studied. benzylaminopurine 109-111 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 60-63 23649227-6 2013 The elevated expression of AOX1 mRNA could be prevented by adding adenine and adenosine which simultaneously reduced the cytotoxic effects of BA and [9R]BA, respectively. benzylaminopurine 142-144 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 27-31 23649227-6 2013 The elevated expression of AOX1 mRNA could be prevented by adding adenine and adenosine which simultaneously reduced the cytotoxic effects of BA and [9R]BA, respectively. benzylaminopurine 153-155 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 27-31 23209126-9 2013 In support of the physiological importance of these findings, we identified the role of proteins mediating BAP-induced ethylene production, METHIONINE SYNTHASE1 and ACC OXIDASE2, in the early root growth response to BAP. benzylaminopurine 216-219 ACC oxidase 2 Arabidopsis thaliana 165-177 23792936-10 2013 Regarding BAP, we observed borderline significant associations with IGF-I or the IGF-I/IGFBP-3 ratio in older subjects only. benzylaminopurine 10-13 insulin like growth factor 1 Homo sapiens 68-73 23792936-10 2013 Regarding BAP, we observed borderline significant associations with IGF-I or the IGF-I/IGFBP-3 ratio in older subjects only. benzylaminopurine 10-13 insulin like growth factor 1 Homo sapiens 81-86 23792936-10 2013 Regarding BAP, we observed borderline significant associations with IGF-I or the IGF-I/IGFBP-3 ratio in older subjects only. benzylaminopurine 10-13 insulin like growth factor binding protein 3 Homo sapiens 87-94 23796564-10 2013 Moreover, a structural equation model revealed that hypertension, low HDL, and insulin resistance had significant direct effects on serum BAP levels, whereas obesity and inflammation might have indirect effects on serum BAP levels. benzylaminopurine 138-141 insulin Homo sapiens 79-86 23078546-9 2013 RESULTS: Log TRACP5b was significantly correlated with log NTX, log BAP and log PTH. benzylaminopurine 68-71 acid phosphatase 5, tartrate resistant Homo sapiens 13-20 23313663-5 2013 Further, we also identified that MMR repression induced by 5 muM BaP was mediated through one of the MMR key proteins MSH6 as significant reduction in protein level was detected by western blot. benzylaminopurine 65-68 mutS homolog 6 Homo sapiens 118-122 23313663-6 2013 More importantly, ectopic expression of hMSH6 restored MMR activity in the BaP treated cells to the same level as in the control cells. benzylaminopurine 75-78 mutS homolog 6 Homo sapiens 40-45 23830844-11 2013 Following multilinear regression analysis and adjustment for all significant co-variables, only eGFR, BAP and 25 (OH)vitamin remained significantly associated with intact PTH and biointact PTH (1-84). benzylaminopurine 102-105 parathyroid hormone Homo sapiens 171-174 24008606-9 2013 BAP values increased in the Pycnogenol group from baseline 1698+-231 to 2349+-294 muM after 8 weeks and dropped to 2002+-203 muM after two weeks washout period. benzylaminopurine 0-3 latexin Homo sapiens 82-85 23800875-5 2013 Injection of GFP(+) OC(+)BAP(+) cells into 8- or 40-week ApoE(-/-) mice led to more extensive calcifications in atherosclerotic areas after 24 or 4 weeks, respectively, compared to control OC(-)BAP(-) cells. benzylaminopurine 25-28 apolipoprotein E Mus musculus 57-61 23800875-11 2013 In conclusion, we show that murine OC(+)BAP(+) cells correspond to human MCCs and promote atherosclerotic calcification in ApoE(-/-) mice, through paracrine activity and modulation of resident cells by AIF-1 overexpression. benzylaminopurine 40-43 apolipoprotein E Homo sapiens 123-127 23800875-11 2013 In conclusion, we show that murine OC(+)BAP(+) cells correspond to human MCCs and promote atherosclerotic calcification in ApoE(-/-) mice, through paracrine activity and modulation of resident cells by AIF-1 overexpression. benzylaminopurine 40-43 allograft inflammatory factor 1 Mus musculus 202-207 23668962-3 2013 Significant positive correlations between HMW-PAHs, Sigma16 EPA-PAHs, and BaP equivalent concentrations in lichens and those in air (TSP) were found. benzylaminopurine 74-77 thrombospondin 1 Homo sapiens 133-136 23430197-8 2013 Serum PTH was positively correlated with 1,25OH2D (p < 0.001), BAP (p = 0.036), sCTX (p = 0.003), and DKK1 (p = 0.007) and negatively with 25OHD (p = 0.002) and sclerostin (p = 0.02). benzylaminopurine 66-69 parathyroid hormone Homo sapiens 6-9 23430197-9 2013 In PHPT patients, serum sclerostin was negatively correlated with BAP (p = 0.038) and sCTX (p = 0.07). benzylaminopurine 66-69 sclerostin Homo sapiens 24-34 23327614-9 2013 In contrast, in the patients with low int-PTH (<60 pg/mL), serum levels of int-PTH and BAP were significantly increased during the A(-)D, without significant changes in serum t-calcium or i-calcium levels. benzylaminopurine 90-93 parathyroid hormone Homo sapiens 42-45 22362819-7 2012 In the combined sample, leptin was positively related to PTH, FGF23, and BAP but not to 1,25D or sclerostin. benzylaminopurine 73-76 leptin Homo sapiens 24-30 23353624-6 2013 RESULTS: Grouped by the TNSALP genotype, a significant negative correlation between serum BAP and phosphorus was observed in 787T>C homozygotes (CC-type), but not in heterozygotes (TCtype), nor in 787T homozygotes (TT-type). benzylaminopurine 90-93 alkaline phosphatase, biomineralization associated Homo sapiens 24-30 23353624-7 2013 CONCLUSIONS: In the present study, we revealed that the single nucleotide polymorphism 787T>C in the TNSALP gene had effects on the correlation between serum BAP and phosphorus in young adult subjects. benzylaminopurine 161-164 alkaline phosphatase, biomineralization associated Homo sapiens 104-110 23354190-10 2013 The serum leptin level was significantly lower in females with PTH >300 pg/mL when compared with patients with PTH = 100-300 pg/mL (86 +- 85 vs 47 +- 48) (P = 0.011).Women with BAP <300 IU/L had significantly higher serum leptin than those with BAP 300-600 IU/L (P = 0.024). benzylaminopurine 180-183 leptin Homo sapiens 10-16 23354190-10 2013 The serum leptin level was significantly lower in females with PTH >300 pg/mL when compared with patients with PTH = 100-300 pg/mL (86 +- 85 vs 47 +- 48) (P = 0.011).Women with BAP <300 IU/L had significantly higher serum leptin than those with BAP 300-600 IU/L (P = 0.024). benzylaminopurine 251-254 leptin Homo sapiens 10-16 22791346-3 2012 The ability of this consortium to utilise HMW PAHs such as pyrene and BaP as a sole carbon source in the presence of toxic metal Cd was demonstrated. benzylaminopurine 70-73 cilia and flagella associated protein 97 Homo sapiens 42-45 22692843-8 2012 The changes in DKK1 were significantly and positively related with the changes in sCTX and bAP and negatively with hip bone mineral density (BMD) changes. benzylaminopurine 91-94 dickkopf WNT signaling pathway inhibitor 1 Homo sapiens 15-19 22692843-9 2012 The changes in sclerostin were significantly and negatively related only with those of bAP. benzylaminopurine 87-90 sclerostin Homo sapiens 15-25 22822037-5 2012 This reporter, designated Lck-BAP-GFP, incorporates green fluorescent protein (GFP) and biotin acceptor peptide (BAP) modules, with the latter allowing its single-step labeling with streptavidin-gold. benzylaminopurine 30-33 LCK proto-oncogene, Src family tyrosine kinase Homo sapiens 26-29 22822037-5 2012 This reporter, designated Lck-BAP-GFP, incorporates green fluorescent protein (GFP) and biotin acceptor peptide (BAP) modules, with the latter allowing its single-step labeling with streptavidin-gold. benzylaminopurine 113-116 LCK proto-oncogene, Src family tyrosine kinase Homo sapiens 26-29 22822037-6 2012 Lck-BAP-GFP was metabolically biotinylated in mammalian cells, distributed into low-density detergent-resistant membrane fractions, and was readily detected with avidin-based reagents. benzylaminopurine 4-7 LCK proto-oncogene, Src family tyrosine kinase Homo sapiens 0-3 22786869-6 2012 Treatment with the exogenous cytokinin N(6)-benzylaminopurine also altered both auxin distribution and patterning of the ovule; this process required the homeodomain transcription factor BELL1 (BEL1). benzylaminopurine 39-61 POX (plant homeobox) family protein Arabidopsis thaliana 187-192 22786869-6 2012 Treatment with the exogenous cytokinin N(6)-benzylaminopurine also altered both auxin distribution and patterning of the ovule; this process required the homeodomain transcription factor BELL1 (BEL1). benzylaminopurine 39-61 POX (plant homeobox) family protein Arabidopsis thaliana 194-198 22203175-8 2012 RESULTS: Serum levels of BAP was significantly lower in patients with nephrotic relapse than those in patients with nephrotic remission or HSP. benzylaminopurine 25-28 heat shock protein 90 beta family member 2, pseudogene Homo sapiens 139-142 22203175-9 2012 BAP correlated well with serum albumin levels. benzylaminopurine 0-3 albumin Homo sapiens 25-38 22579549-12 2012 Coupled with reduced androgen levels, elevated IGF-I levels, which were positively correlated with BAP during ADT, possibly explain the mechanism of ADT-related high bone turnover. benzylaminopurine 99-102 insulin like growth factor 1 Homo sapiens 47-52 22362819-8 2012 Multiple regression analysis demonstrated that PTH was predicted by leptin and Ca (R(2) = 0.39); 1,25D by 25D, FGF23, and phosphate (R(2) = 0.43); FGF23 by leptin and 1,25D (R(2) = 0.27); BAP by leptin, PTH, and Ca (R(2) = 0.39); and sclerostin by leptin and PTH (R(2) = 0.20). benzylaminopurine 188-191 parathyroid hormone Homo sapiens 47-50 22564653-10 2012 Additionally, insulin and albumin secretion from the CSI-BAP was confirmed by in vivo immunohistochemical examination. benzylaminopurine 57-60 insulin Homo sapiens 14-21 21761256-2 2011 The highest micropropagation coefficient was obtained using half-strength Murashige-Skoog medium supplemented with 0.4 muM 6-benzyladenine (BA). benzylaminopurine 123-138 latexin Homo sapiens 119-122 22312114-3 2012 In this report, the question has been addressed whether members of the small family of Arabidopsis CK receptors (AHK2, AHK3, CRE1/AHK4) are required for BA-induced PCD. benzylaminopurine 153-155 histidine kinase 2 Arabidopsis thaliana 113-117 22312114-3 2012 In this report, the question has been addressed whether members of the small family of Arabidopsis CK receptors (AHK2, AHK3, CRE1/AHK4) are required for BA-induced PCD. benzylaminopurine 153-155 histidine kinase 3 Arabidopsis thaliana 119-123 22312114-3 2012 In this report, the question has been addressed whether members of the small family of Arabidopsis CK receptors (AHK2, AHK3, CRE1/AHK4) are required for BA-induced PCD. benzylaminopurine 153-155 CHASE domain containing histidine kinase protein Arabidopsis thaliana 125-129 22312114-3 2012 In this report, the question has been addressed whether members of the small family of Arabidopsis CK receptors (AHK2, AHK3, CRE1/AHK4) are required for BA-induced PCD. benzylaminopurine 153-155 CHASE domain containing histidine kinase protein Arabidopsis thaliana 130-134 22178539-9 2012 Changes in serum sclerostin at 12 months were negatively correlated with changes in bAP (P<0.001) even when data were adjusted for sCTX changes and only treated patients were included. benzylaminopurine 84-87 sclerostin Homo sapiens 17-27 22176742-3 2012 We tested how the percent BAP (%BAP) varied with different P removal levels using an algal growth bioassay methodology. benzylaminopurine 26-29 prohibitin 2 Homo sapiens 31-35 22474430-5 2012 We found that DM patients had significantly higher expression of OC and BAP on circulating CD34+ cells than control subjects, especially in the presence of CAD. benzylaminopurine 72-75 CD34 molecule Homo sapiens 91-95 23189153-6 2012 Carr), respectively, for dROM; 1,951+-282, 1,969+-252, and 2,033+-252 (micromol/L), respectively, for BAP (micromol/L); and 614+-98, 584+-91, and 617+-99 (micromol/L), respectively, for SH. benzylaminopurine 102-105 arrestin 3 Homo sapiens 0-4 22911822-8 2012 Gene function knockdown of members of the BAP chromatin-remodeling complex resulted in niche cells that do not express the hedgehog (hh) gene and fail to differentiate filopodia believed important for Hh signaling from the niche to progenitors. benzylaminopurine 42-45 hedgehog Drosophila melanogaster 133-135 22161252-9 2011 TRACP5b, P1CP, and BAP levels significantly decreased by 40-70% relative to vehicle controls in the OPG-Fc group between days 5 and 10, indicating that pharmacologic concentration of OPG-Fc led to systemic concomitant inhibition of bone formation and resorption in young growing pigs. benzylaminopurine 19-22 basic transcription factor 3 pseudogene 11 Homo sapiens 100-103 22161252-9 2011 TRACP5b, P1CP, and BAP levels significantly decreased by 40-70% relative to vehicle controls in the OPG-Fc group between days 5 and 10, indicating that pharmacologic concentration of OPG-Fc led to systemic concomitant inhibition of bone formation and resorption in young growing pigs. benzylaminopurine 19-22 basic transcription factor 3 pseudogene 11 Homo sapiens 183-186 21761256-2 2011 The highest micropropagation coefficient was obtained using half-strength Murashige-Skoog medium supplemented with 0.4 muM 6-benzyladenine (BA). benzylaminopurine 140-142 latexin Homo sapiens 119-122 21980959-9 2011 IGF-1 and MVPA were significant predictors of BAP in the group as a whole. benzylaminopurine 46-49 insulin like growth factor 1 Homo sapiens 0-5 21980959-10 2011 However, examined separately, IGF-1 was a predictor of BAP in the premenarcheal group while MVPA was a predictor in the postmenarcheal group. benzylaminopurine 55-58 insulin like growth factor 1 Homo sapiens 30-35 20551433-2 2010 A common multisubunit core, containing the Brahma ATPase, can associate either with Osa to form the BAP complex or with Bap170, Bap180, and Sayp to constitute the PBAP complex. benzylaminopurine 100-103 brahma Drosophila melanogaster 43-49 21742755-5 2011 RESULTS: BAP-PIQ subscales were significantly associated with child functional disability, whereas BSI subscales were unrelated. benzylaminopurine 9-12 IQ motif containing B1 Homo sapiens 13-16 21159027-7 2011 RESULTS: For 25-(OH)D <= 50 nmol/L, PTH and BAP were both inversely correlated with 25-(OH)D (PTH, r=-0.864, P < 0.01; BAP, r=-0.856, P < 0.01). benzylaminopurine 47-50 parathyroid hormone Homo sapiens 97-100 21159027-7 2011 RESULTS: For 25-(OH)D <= 50 nmol/L, PTH and BAP were both inversely correlated with 25-(OH)D (PTH, r=-0.864, P < 0.01; BAP, r=-0.856, P < 0.01). benzylaminopurine 125-128 parathyroid hormone Homo sapiens 39-42 21205031-6 2011 Treatment of selected mutants confirmed that TSF and SOC1 are necessary for the flowering response to BAP, whereas the activation cascade might partially act independently of FD. benzylaminopurine 102-105 PEBP (phosphatidylethanolamine-binding protein) family protein Arabidopsis thaliana 45-48 21205031-6 2011 Treatment of selected mutants confirmed that TSF and SOC1 are necessary for the flowering response to BAP, whereas the activation cascade might partially act independently of FD. benzylaminopurine 102-105 AGAMOUS-like 20 Arabidopsis thaliana 53-57 21134679-5 2011 The use of these C18 stationary phases allows to reach more accurate conclusion on the comparison of the shape selectivity values provided either by the cis/trans beta-carotene selectivity or by the TRI/oTER or TbN/BaP ones. benzylaminopurine 215-218 Bardet-Biedl syndrome 9 Homo sapiens 17-20 21651892-4 2011 We find that fusion of the biotin-acceptor peptide (BAP) and transmembrane domain of the platelet-derived growth factor receptor (PDGFR) to the N-terminus of prestin-GFP yields a membrane protein that can be metabolically-labeled with biotin, trafficked to the plasma membrane, and selectively detected at the plasma membrane using fluorescently-tagged streptavidin. benzylaminopurine 52-55 solute carrier family 26 member 5 Homo sapiens 158-165 21316482-8 2011 Addition of the antioxidant N-acetyl-l-cysteine (NAC) markedly reduced the ROS level and partly suppressed the DNA strand breaks induced by BDE47 or/and BaP. benzylaminopurine 153-156 X-linked Kx blood group Homo sapiens 49-52 21316482-10 2011 The real-time PCR results showed that BaP could significantly induce the expression of CYP1A1 and CYP1B1, however, the pre-treatment with BDE47 appeared to attenuate the BaP-induced CYP1 expression. benzylaminopurine 38-41 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 87-93 21316482-10 2011 The real-time PCR results showed that BaP could significantly induce the expression of CYP1A1 and CYP1B1, however, the pre-treatment with BDE47 appeared to attenuate the BaP-induced CYP1 expression. benzylaminopurine 38-41 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 98-104 21316482-10 2011 The real-time PCR results showed that BaP could significantly induce the expression of CYP1A1 and CYP1B1, however, the pre-treatment with BDE47 appeared to attenuate the BaP-induced CYP1 expression. benzylaminopurine 38-41 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 87-91 20675043-9 2010 Using the toxic equivalent factor (TEF), the mean contributions of the carcinogenic potency of BaP to the air samples collected at the arc furnace and rolling mill (fraction below 0.25 mum) were determined to be 66.3% and 50.3%, respectively. benzylaminopurine 95-98 TEF transcription factor, PAR bZIP family member Homo sapiens 10-33 20675043-9 2010 Using the toxic equivalent factor (TEF), the mean contributions of the carcinogenic potency of BaP to the air samples collected at the arc furnace and rolling mill (fraction below 0.25 mum) were determined to be 66.3% and 50.3%, respectively. benzylaminopurine 95-98 TEF transcription factor, PAR bZIP family member Homo sapiens 35-38 20676891-7 2010 Additionally, GhHB4 expression was enhanced by 6-BA treatment. benzylaminopurine 47-51 homeobox-leucine zipper protein HAT22-like Gossypium hirsutum 14-19 20551433-3 2010 Although required for many biological processes, recent genetic analyses revealed that one role of the BAP complex during Drosophila wing development is the proper regulation of EGFR target genes. benzylaminopurine 103-106 Epidermal growth factor receptor Drosophila melanogaster 178-182 19854261-0 2010 Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. benzylaminopurine 47-68 aryl hydrocarbon receptor Homo sapiens 84-87 20471113-7 2010 Exposure of KC embryos to BaP, BkF, and PCB126 induced CYP1A activity and cardiac deformities. benzylaminopurine 26-29 cytochrome P450 1A1 Fundulus heteroclitus 55-60 20471113-10 2010 CYP1A, CYP1B1 and CYP1C1 mRNA were all significantly induced in the KC embryos after exposure to BaP, BkF and PCB126. benzylaminopurine 97-100 cytochrome P450 1A1 Fundulus heteroclitus 0-5 20471113-11 2010 Exposure to BaP and BkF in ER embryos resulted in a significant induction of CYP1A mRNA, albeit significantly lower than observed in KC fish. benzylaminopurine 12-15 cytochrome P450 1A1 Fundulus heteroclitus 77-82 22993544-8 2010 The median concentration of SMRP in MPM, LC, BAP, TP and CHF were 11.5 (range 0.90-82.80), 5.20 (0.05-36.40), 6.65 (1.45-11.25), 3.20 (1.65-6.50) and 2.03 (1.35-2.80) nmol/l, respectively. benzylaminopurine 45-48 mesothelin Homo sapiens 28-32 19854261-0 2010 Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. benzylaminopurine 47-68 nuclear receptor subfamily 1 group I member 2 Homo sapiens 92-95 19854261-0 2010 Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. benzylaminopurine 47-68 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 137-143 19854261-0 2010 Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes. benzylaminopurine 47-68 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 148-154 19493962-2 2009 Additionally, induction of AtCOX6b-1 by GA(3) and AtCOX6b-3 by 6-benzylaminopurine was observed. benzylaminopurine 63-82 cytochrome C oxidase 6B Arabidopsis thaliana 27-34 19912332-3 2009 At all ages [postnatal day (P)8, P14, P21] the bAP-evoked calcium transient amplitude increased with distance from the soma with a peak at around 50 microm, followed by a gradual decline in amplitude. benzylaminopurine 47-50 S100 calcium binding protein A9 Rattus norvegicus 33-36 19912332-3 2009 At all ages [postnatal day (P)8, P14, P21] the bAP-evoked calcium transient amplitude increased with distance from the soma with a peak at around 50 microm, followed by a gradual decline in amplitude. benzylaminopurine 47-50 KRAS proto-oncogene, GTPase Rattus norvegicus 38-41 19508462-7 2009 The addition of albumin resulted in increased transfer of BaP from maternal to foetal reservoirs. benzylaminopurine 58-61 albumin Homo sapiens 16-23 19508462-9 2009 Less BaP accumulated in placental tissue in perfusions with added albumin. benzylaminopurine 5-8 albumin Homo sapiens 66-73 19641839-6 2009 Our results suggest that poor diabetic control and lower IGF-I level are linked to impaired bone formation and resultant reduction in OC/BAP ratio in men with type 2 diabetes. benzylaminopurine 137-140 insulin like growth factor 1 Homo sapiens 57-62 19493962-2 2009 Additionally, induction of AtCOX6b-1 by GA(3) and AtCOX6b-3 by 6-benzylaminopurine was observed. benzylaminopurine 63-82 cytochrome C oxidase 6B Arabidopsis thaliana 50-57 19519245-1 2009 Human BAP31 is a 28 kDa polytopic integral protein of the ER and part of a large BAP hetero-oligomeric complex that includes the related BAP29 protein and connections to actomyosin. benzylaminopurine 6-9 B cell receptor associated protein 29 Homo sapiens 137-142 19306864-0 2009 Osa, a subunit of the BAP chromatin-remodelling complex, participates in the regulation of gene expression in response to EGFR signalling in the Drosophila wing. benzylaminopurine 22-25 osa Drosophila melanogaster 0-3 19306864-0 2009 Osa, a subunit of the BAP chromatin-remodelling complex, participates in the regulation of gene expression in response to EGFR signalling in the Drosophila wing. benzylaminopurine 22-25 Epidermal growth factor receptor Drosophila melanogaster 122-126 19306864-5 2009 Other members of the BAP complex, such as Snr1, Bap55, Mor and Brm, also share these functions of Osa. benzylaminopurine 21-24 Snf5-related 1 Drosophila melanogaster 42-46 19306864-5 2009 Other members of the BAP complex, such as Snr1, Bap55, Mor and Brm, also share these functions of Osa. benzylaminopurine 21-24 Brahma associated protein 55kD Drosophila melanogaster 48-53 19306864-5 2009 Other members of the BAP complex, such as Snr1, Bap55, Mor and Brm, also share these functions of Osa. benzylaminopurine 21-24 moira Drosophila melanogaster 55-58 19306864-5 2009 Other members of the BAP complex, such as Snr1, Bap55, Mor and Brm, also share these functions of Osa. benzylaminopurine 21-24 brahma Drosophila melanogaster 63-66 19306864-5 2009 Other members of the BAP complex, such as Snr1, Bap55, Mor and Brm, also share these functions of Osa. benzylaminopurine 21-24 osa Drosophila melanogaster 98-101 19123006-4 2009 Melanin content and tyrosinase activity increased in response to treatment with 6-BAP in a concentration-dependent manner. benzylaminopurine 80-85 tyrosinase Mus musculus 20-30 19221880-6 2009 Transgenic lines with reduced expression of StCDPK1 (beta 7) did not differ from controls when cultured under multiplication conditions, but when grown under tuber inducing conditions some significant differences were observed: the beta 7 line tuberized earlier than controls without the addition of CCC (GA inhibitor), developed more tubers than wild type plants in the presence of hormones that promote tuberization in potato (ABA and BAP) and was more insensitive to GA action (stolons were significantly shorter than those of control plants). benzylaminopurine 437-440 calcium-dependent protein kinase Solanum tuberosum 44-51 19221880-7 2009 StCDPK1 expression was induced by GA, ABA and BAP. benzylaminopurine 46-49 calcium-dependent protein kinase Solanum tuberosum 0-7 19538838-8 2009 CONCLUSION: BAP concentration of work environment contributes to the elevated urinary 1-hydroxypyrene levels, and the exposed BAP levels were regulated by the CYP1A1 MspI and I462V genotypes. benzylaminopurine 126-129 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 159-165 18566000-2 2008 The distance-dependent increase in Kv4.2-mediated A-type K(+) current along the apical dendrites of CA1 pyramidal cells (CA1 PCs) is responsible for the attenuation of bAP amplitude with distance from the soma. benzylaminopurine 168-171 potassium voltage-gated channel, Shal-related family, member 2 Mus musculus 35-40 19775531-11 2009 We were able to significantly increase the blood flow and the number of new blood vessels in the tissue surrounding the BAP device by using gelatinized bFGF. benzylaminopurine 120-123 fibroblast growth factor 2 Rattus norvegicus 152-156 19775531-14 2009 We confirmed in this study that the use of an implantable BAP device and bFGF allowed for a better blood flow around the BAP device. benzylaminopurine 121-124 fibroblast growth factor 2 Rattus norvegicus 73-77 19123006-5 2009 The tyrosinase, TRP-1, TRP-2 and MITF protein levels were found to increase significantly in response to 6-BAP in a time-dependent manner. benzylaminopurine 105-110 tyrosinase Mus musculus 4-14 19123006-5 2009 The tyrosinase, TRP-1, TRP-2 and MITF protein levels were found to increase significantly in response to 6-BAP in a time-dependent manner. benzylaminopurine 105-110 tyrosinase-related protein 1 Mus musculus 16-21 19123006-5 2009 The tyrosinase, TRP-1, TRP-2 and MITF protein levels were found to increase significantly in response to 6-BAP in a time-dependent manner. benzylaminopurine 105-110 tRNA proline 2 Mus musculus 23-28 19123006-5 2009 The tyrosinase, TRP-1, TRP-2 and MITF protein levels were found to increase significantly in response to 6-BAP in a time-dependent manner. benzylaminopurine 105-110 melanogenesis associated transcription factor Mus musculus 33-37 19123006-7 2009 The increased melanin synthesis that was induced by treatment with 6-BAP treatment was reduced significantly in response to co-treatment with H-89 [a protein kinase A (PKA) inhibitor], whereas co-treatment with SB203580 (a p38 MAPK inhibitor) and Ro-32-0432 (a PKC inhibitor) did not attenuate the increase in melanin content levels that was induced by 6-BAP. benzylaminopurine 67-72 mitogen-activated protein kinase 14 Mus musculus 223-231 19123006-9 2009 These findings suggest that 6-BAP activates PKA via a cAMP-independent pathway and subsequently stimulates melanogenesis by up-regulating MITF and tyrosinase expression. benzylaminopurine 28-33 melanogenesis associated transcription factor Mus musculus 138-142 19123006-9 2009 These findings suggest that 6-BAP activates PKA via a cAMP-independent pathway and subsequently stimulates melanogenesis by up-regulating MITF and tyrosinase expression. benzylaminopurine 28-33 tyrosinase Mus musculus 147-157 18573871-3 2008 In Drosophila, the core Brahma complex associates either with Osa to form the BAP complex or with Bap170 and Bap180 to form the PBAP complex. benzylaminopurine 78-81 brahma Drosophila melanogaster 24-30 18566000-2 2008 The distance-dependent increase in Kv4.2-mediated A-type K(+) current along the apical dendrites of CA1 pyramidal cells (CA1 PCs) is responsible for the attenuation of bAP amplitude with distance from the soma. benzylaminopurine 168-171 carbonic anhydrase 1 Mus musculus 100-103 18566000-2 2008 The distance-dependent increase in Kv4.2-mediated A-type K(+) current along the apical dendrites of CA1 pyramidal cells (CA1 PCs) is responsible for the attenuation of bAP amplitude with distance from the soma. benzylaminopurine 168-171 carbonic anhydrase 1 Mus musculus 121-124 18566000-3 2008 Genetic deletion of Kv4.2 reduced dendritic A-type K(+) current and increased the bAP amplitude in distal dendrites. benzylaminopurine 82-85 potassium voltage-gated channel, Shal-related family, member 2 Mus musculus 20-25 18299390-2 2008 BAP and PBAP are the fly representatives of the two evolutionarily conserved major subclasses of SWI/SNF remodelers. benzylaminopurine 0-3 halfway Drosophila melanogaster 97-104 18299390-5 2008 Biochemical analysis established that SAYP is tightly associated with PBAP but absent from BAP. benzylaminopurine 71-74 enhancer of yellow 3 Drosophila melanogaster 38-42 18230350-11 2008 The significant positive correlations between MT1-MMP and BAP, NTX were found, and remained significant after adjustment for age and BMI (all P<0.05). benzylaminopurine 58-61 matrix metallopeptidase 14 Homo sapiens 46-53 18189313-4 2008 Here, we show the effects of low-dose (1 microM) nicotine on bAP-evoked Ca2+ transients in basal dendrites and spines of pyramidal neurons in rat hippocampal slices. benzylaminopurine 61-64 carbonic anhydrase 2 Rattus norvegicus 72-75 18189313-5 2008 Although nicotine application failed to have any direct effect in low concentration, it could significantly enhance bAP-evoked Ca2+ transients through presynaptic nAChRs located on axon terminals innervating pyramidal cells. benzylaminopurine 116-119 carbonic anhydrase 2 Rattus norvegicus 127-130 17485137-7 2007 BAP increased the activities of catalase (CAT, EC 1.11.1.6) and ascorbate peroxidase (APX, EC 1.11.1.11) and reduced the level of H(2)O(2) in the delayed-senescence tissue. benzylaminopurine 0-3 catalase-1 Triticum aestivum 32-40 17485137-7 2007 BAP increased the activities of catalase (CAT, EC 1.11.1.6) and ascorbate peroxidase (APX, EC 1.11.1.11) and reduced the level of H(2)O(2) in the delayed-senescence tissue. benzylaminopurine 0-3 catalase-1 Triticum aestivum 42-45 17485137-7 2007 BAP increased the activities of catalase (CAT, EC 1.11.1.6) and ascorbate peroxidase (APX, EC 1.11.1.11) and reduced the level of H(2)O(2) in the delayed-senescence tissue. benzylaminopurine 0-3 peroxidase-like Triticum aestivum 74-84 17485137-7 2007 BAP increased the activities of catalase (CAT, EC 1.11.1.6) and ascorbate peroxidase (APX, EC 1.11.1.11) and reduced the level of H(2)O(2) in the delayed-senescence tissue. benzylaminopurine 0-3 POD1 Triticum aestivum 86-89 17485137-8 2007 The present research indicates that BAP reduces levels of reactive oxygen species (ROS), and enhances the activity of antioxidant enzymes (CAT, APX). benzylaminopurine 36-39 catalase-1 Triticum aestivum 139-142 17485137-8 2007 The present research indicates that BAP reduces levels of reactive oxygen species (ROS), and enhances the activity of antioxidant enzymes (CAT, APX). benzylaminopurine 36-39 POD1 Triticum aestivum 144-147 17680245-2 2007 A two-layer (Gelrite-solidified layer topped with a layer of liquid medium of the same volume and composition) culture system containing benzyladenine (BA) at 11.1 muM induced the highest percent of flowering (45%) in plantlets within 6 months from germination. benzylaminopurine 137-150 latexin Homo sapiens 164-167 17680245-2 2007 A two-layer (Gelrite-solidified layer topped with a layer of liquid medium of the same volume and composition) culture system containing benzyladenine (BA) at 11.1 muM induced the highest percent of flowering (45%) in plantlets within 6 months from germination. benzylaminopurine 152-154 latexin Homo sapiens 164-167 17101803-10 2007 BAP mediates G(2)/M transition through direct regulation of string/cdc25. benzylaminopurine 0-3 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 60-72 17984250-6 2007 RESULTS: Serum IGF-I SDS levels were positively correlated with BAP and CrossLaps SDS levels before and after puberty, and also with CrossLaps during puberty (weak correlation). benzylaminopurine 64-67 insulin like growth factor 1 Homo sapiens 15-20 17984250-7 2007 Serum IGFBP-3 SDS levels were positively correlated with BAP and CrossLaps levels before, during (weak correlation) and after puberty (for BAP levels only). benzylaminopurine 57-60 insulin like growth factor binding protein 3 Homo sapiens 6-13 17984250-7 2007 Serum IGFBP-3 SDS levels were positively correlated with BAP and CrossLaps levels before, during (weak correlation) and after puberty (for BAP levels only). benzylaminopurine 139-142 insulin like growth factor binding protein 3 Homo sapiens 6-13 17676199-8 2007 Positive correlations were detected between serum IGF-1 levels and each of BAP, alkaline phosphatase, and osteocalcin in diabetic rats treated by leptin, and those with leptin plus insulin. benzylaminopurine 75-78 insulin-like growth factor 1 Rattus norvegicus 50-55 17556810-3 2007 Results of semi-quantitative reverse transcription PCR (RT-PCR) analysis indicated that AtCPK30 was highly expressed in root and induced by ABA, IAA, 2,4-D, GA(3) and 6-BA treatment. benzylaminopurine 167-171 calcium-dependent protein kinase 30 Arabidopsis thaliana 88-95 17101803-11 2007 Its signature subunit, OSA, is required for directing BAP to the string/cdc25 promoter. benzylaminopurine 54-57 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 65-77 17213797-3 2006 BaP 7,8-diol 9,10-epoxide (BPDE), an ultimate metabolite of BaP, attacks deoxyguanosine to form a BPDE-N2-dG adduct resulting in p53 mutations. benzylaminopurine 0-3 tumor protein p53 Homo sapiens 129-132 16188888-1 2005 When human DNA polymerase eta (pol eta) encounters N6-deoxyadenosine adducts formed by trans epoxide ring opening of the 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BaP DE) isomer with (+)-7R,8S,9S,10R configuration ((+)-BaP DE-2), misincorporation of A or G and incorporation of the correct T are equally likely to occur. benzylaminopurine 181-184 DNA polymerase eta Homo sapiens 11-29 17213797-3 2006 BaP 7,8-diol 9,10-epoxide (BPDE), an ultimate metabolite of BaP, attacks deoxyguanosine to form a BPDE-N2-dG adduct resulting in p53 mutations. benzylaminopurine 60-63 tumor protein p53 Homo sapiens 129-132 21783661-2 2006 UGT1A1 and UGT1A7 were found to be broadly active towards BaP metabolites. benzylaminopurine 58-61 UDP glucuronosyltransferase family 1 member A1 Rattus norvegicus 0-6 21783661-2 2006 UGT1A1 and UGT1A7 were found to be broadly active towards BaP metabolites. benzylaminopurine 58-61 UDP glucuronosyltransferase family 1 member A6 Rattus norvegicus 11-17 21783661-7 2006 These data suggest that multiple UGT1A enzymes contribute to glucuronidation of BPD and other BaP metabolites, and that their relative contributions depend on tissue- and environmental-specific factors. benzylaminopurine 94-97 Ugt1a@ Rattus norvegicus 33-38 16214355-7 2006 In contrast to their high activity in bioassays, the BAP derivatives were recognised with much lower sensitivity than trans-zeatin in both Arabidopsis thaliana AHK3 and AHK4 receptor assays. benzylaminopurine 53-56 histidine kinase 3 Arabidopsis thaliana 160-164 16214355-7 2006 In contrast to their high activity in bioassays, the BAP derivatives were recognised with much lower sensitivity than trans-zeatin in both Arabidopsis thaliana AHK3 and AHK4 receptor assays. benzylaminopurine 53-56 CHASE domain containing histidine kinase protein Arabidopsis thaliana 169-173 16386795-1 2006 The synthesis, characterization and biological activity of the first zinc(II) complexes with potent inhibitors of cyclin-dependent kinases (CDKs) derived from 6-benzylaminopurine are described. benzylaminopurine 159-178 cyclin dependent kinase 2 Homo sapiens 140-144 16888370-10 2006 Our results additionally showed significant positive correlationsbetween baseline levels of serum IL-6 and those of iPTH, bAP and TRACP5b. benzylaminopurine 122-125 interleukin 6 Homo sapiens 98-102 16888370-12 2006 CONCLUSIONS: Elevated levels of serum IL-6 and bone remodeling markers, namely, bAP and TRACP5b which are common features of SHP, are effectively suppressed by calcitriol therapy. benzylaminopurine 80-83 interleukin 6 Homo sapiens 38-42 17122039-6 2006 The absence of dendritic Kv4.2-encoded A-type K+ currents led to an increase of bAP amplitude and an increase of concurrent Ca2+ influx. benzylaminopurine 80-83 potassium voltage-gated channel, Shal-related family, member 2 Mus musculus 25-30 16697458-9 2006 BaP exposure significantly induced CYP1B message in blood, gonad, and liver of laboratory catfish. benzylaminopurine 0-3 cytochrome P450, family 1, subfamily B, polypeptide 1 Danio rerio 35-40 16889510-8 2006 In addition, regulation of insulin secretion from the BAP was properly controlled in response to glucose both in vitro and in vivo. benzylaminopurine 54-57 insulin Sus scrofa 27-34 16780680-7 2006 (4) Positive correlation was found between MMP-2 and BAP, OC, NTX (all P < 0.001). benzylaminopurine 53-56 matrix metallopeptidase 2 Homo sapiens 43-48 16121241-7 2005 Hormone-treated seedlings showed increased RPL23A-1 and -2 transcript levels following IAA and BAP treatment while ABA treatment resulted in a transient lowering of transcript levels. benzylaminopurine 95-98 ribosomal protein L23AA Arabidopsis thaliana 43-58 16189633-11 2005 CONCLUSIONS: OCT is as effective as oral calcitriol pulse therapy in suppressing intact PTH and BAP in chronic hemodialysis patients. benzylaminopurine 96-99 plexin A2 Homo sapiens 13-16 16004970-4 2005 Here, we show that Tin and Bagpipe (Bap), another homeodomain protein, form homo- and heterodimeric complexes. benzylaminopurine 36-39 tinman Drosophila melanogaster 19-22 15322741-6 2005 Serum Bio-PTH and I-PTH correlated significantly in a positive manner with serum bone formation markers (BAP, iOC, N-Mid OC, PINP), and resorption markers (DPD, PYD, beta-CTx), and in a negative manner with BMD and annual change therein at distal radius one-third. benzylaminopurine 105-108 parathyroid hormone Homo sapiens 10-13 15322741-6 2005 Serum Bio-PTH and I-PTH correlated significantly in a positive manner with serum bone formation markers (BAP, iOC, N-Mid OC, PINP), and resorption markers (DPD, PYD, beta-CTx), and in a negative manner with BMD and annual change therein at distal radius one-third. benzylaminopurine 105-108 parathyroid hormone Homo sapiens 20-23 15684669-9 2004 Consequently, the coencapsulation of VAPG or GLP-1/Zn(2+) crystal can be a potential approach to reducing BAP volume with further optimization of activity duration. benzylaminopurine 106-109 glucagon Homo sapiens 45-50 15750188-8 2005 Adjacent binding sites for the FoxG transcription factors encoded by the Sloppy paired genes (slp1 and slp2), which are direct targets of the Wg signaling cascade, serve to block the synergistic activity of Tin and activated Smads during bap induction. benzylaminopurine 238-241 sloppy paired 2 Drosophila melanogaster 31-35 15750188-8 2005 Adjacent binding sites for the FoxG transcription factors encoded by the Sloppy paired genes (slp1 and slp2), which are direct targets of the Wg signaling cascade, serve to block the synergistic activity of Tin and activated Smads during bap induction. benzylaminopurine 238-241 sloppy paired 1 Drosophila melanogaster 94-98 15750188-8 2005 Adjacent binding sites for the FoxG transcription factors encoded by the Sloppy paired genes (slp1 and slp2), which are direct targets of the Wg signaling cascade, serve to block the synergistic activity of Tin and activated Smads during bap induction. benzylaminopurine 238-241 sloppy paired 2 Drosophila melanogaster 103-107 15750188-8 2005 Adjacent binding sites for the FoxG transcription factors encoded by the Sloppy paired genes (slp1 and slp2), which are direct targets of the Wg signaling cascade, serve to block the synergistic activity of Tin and activated Smads during bap induction. benzylaminopurine 238-241 tinman Drosophila melanogaster 207-210 15750188-9 2005 In addition, we show that binding sites for yet unknown repressors are essential to prevent the induction of the bap enhancer by Dpp in the dorsal ectoderm. benzylaminopurine 113-116 decapentaplegic Drosophila melanogaster 129-132 15901049-5 2005 Significantly decreased concentrations of beta2-MG, IL-6 and total protein were found in both BAP and BP. benzylaminopurine 94-97 interleukin 6 Homo sapiens 52-56 15901049-6 2005 Additionally, IL-8 was significantly reduced in BP, and ICAM-1 and albumin were present in lower concentrations in BAP. benzylaminopurine 115-118 C-X-C motif chemokine ligand 8 Homo sapiens 14-18 15901049-6 2005 Additionally, IL-8 was significantly reduced in BP, and ICAM-1 and albumin were present in lower concentrations in BAP. benzylaminopurine 115-118 intercellular adhesion molecule 1 Homo sapiens 56-62 15728338-3 2005 Here we show that hydroxylated derivatives of benzyladenine (topolins) are also substrates of ZOG1 and cisZOG1. benzylaminopurine 46-59 cis-zeatin O-glucosyltransferase 1 Zea mays 103-110 15550247-3 2004 We engineered a ClpB variant, BAP, which associates with the ClpP peptidase and thereby is converted into a degrading disaggregase. benzylaminopurine 30-33 caseinolytic mitochondrial matrix peptidase chaperone subunit B Homo sapiens 16-20 15550247-3 2004 We engineered a ClpB variant, BAP, which associates with the ClpP peptidase and thereby is converted into a degrading disaggregase. benzylaminopurine 30-33 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 61-65 15550247-4 2004 BAP translocates substrates through its central pore directly into ClpP for degradation. benzylaminopurine 0-3 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 67-71 15550247-6 2004 Protein disaggregation by the BAP/ClpP complex remains dependent on DnaK, defining a role for DnaK at early stages of the disaggregation reaction. benzylaminopurine 30-33 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 34-38 15949377-7 2005 (3) Positive correlations between MMP-2 and BAP, OC, NTX was found (all r = 0.193, 0.231, 0.249, P < 0.01) (4) Serum MMP-2 concentrations were significantly higher in postmenopausal women with osteoporosis (1466 microg/L +/- 313 microg/L) than in age-matched normal controls (1222 microg/L +/- 243 microg/L) and osteopenia subjects (1282 microg/L +/- 220 microg/L). benzylaminopurine 44-47 matrix metallopeptidase 2 Homo sapiens 34-39 15545295-0 2005 Differential response of PCNA and Cdk-A proteins and associated kinase activities to benzyladenine and abscisic acid during maize seed germination. benzylaminopurine 85-98 proliferating cell nuclear antigen Zea mays 25-29 15813218-4 2005 Pretreatment with 10 and 100 microM of BA significantly increased superoxide dismutase (SOD) activity after 8 h of PQ treatment but there was no significant change in SOD activity in the leaves pretreated with BA at 12 and 24 h. However, peroxidase activity significantly increased in 100 microM of BA pretreated leaves. benzylaminopurine 39-41 superoxide dismutase Zea mays 66-86 15813218-4 2005 Pretreatment with 10 and 100 microM of BA significantly increased superoxide dismutase (SOD) activity after 8 h of PQ treatment but there was no significant change in SOD activity in the leaves pretreated with BA at 12 and 24 h. However, peroxidase activity significantly increased in 100 microM of BA pretreated leaves. benzylaminopurine 39-41 superoxide dismutase Zea mays 88-91 15813218-4 2005 Pretreatment with 10 and 100 microM of BA significantly increased superoxide dismutase (SOD) activity after 8 h of PQ treatment but there was no significant change in SOD activity in the leaves pretreated with BA at 12 and 24 h. However, peroxidase activity significantly increased in 100 microM of BA pretreated leaves. benzylaminopurine 39-41 peroxidase 1 Zea mays 238-248 15153786-9 2004 Serum TRACP 5b activity correlated well with BAP activity in breast cancer patients with bone metastasis (p < 0.0001), but not in normal individuals or in patients without bone metastasis. benzylaminopurine 45-48 acid phosphatase 5, tartrate resistant Homo sapiens 6-14 15456814-3 2004 The R- and T-type Ca2+ channel blocker NiCl2 (100 microm) significantly reduced Ca2+ transients in both spines and their parent dendrites (approximately 50%), suggesting that these channels are the major source of bAP-evoked Ca2+ influx in these structures. benzylaminopurine 214-217 carbonic anhydrase 2 Homo sapiens 18-21 15462112-15 2004 Serum ACE activity was positively correlated with serum iPTH (R=0.29, p=0.02), serum OC (R=0.35, p=0.01), serum bAP (R=0.34, p=0.01), serum PCIP (R=0.36, p=0.01). benzylaminopurine 112-115 angiotensin I converting enzyme Homo sapiens 6-9 12792991-5 2003 It was suggested that BaP restrained proliferative activities of porcine aortic endothelial cells, which may be related to the inhibition of HSP70 expression by BaP. benzylaminopurine 22-25 heat shock protein family A (Hsp70) member 4 Homo sapiens 141-146 15041469-8 2004 This was the first study that reports that BaP and BPDE reduced endogenous AR expression. benzylaminopurine 43-46 androgen receptor Homo sapiens 75-77 15041469-9 2004 These data suggest that metabolically activated BaP may disrupt androgen function by reducing AR levels in androgen-responsive organs. benzylaminopurine 48-51 androgen receptor Homo sapiens 94-96 12886015-9 2003 Thus, BAP complexes contribute to ER retention of mIg complexes that are not bound to Ig-alpha/Ig-beta. benzylaminopurine 6-9 chemokine (C-X-C motif) ligand 9 Mus musculus 50-53 12886015-9 2003 Thus, BAP complexes contribute to ER retention of mIg complexes that are not bound to Ig-alpha/Ig-beta. benzylaminopurine 6-9 chemokine (C-X-C motif) ligand 9 Mus musculus 51-53 12687018-4 2003 Treatment with 3 microM BaP, a hydrocarbon ligand of Ahr, inhibited glomerulogenesis and branching morphogenesis of metanephric kidneys. benzylaminopurine 24-27 aryl-hydrocarbon receptor Mus musculus 53-56 12687018-7 2003 A significant decrease in total WT1 protein was observed by both immunocytochemistry and Western analysis in cultures challenged with BaP compared to controls. benzylaminopurine 134-137 WT1 transcription factor Mus musculus 32-35 15041469-3 2004 Treatment with 1microM BaP tremendously reduced constitutive androgen receptor (AR) expression, as determined with Western immunoblotting and the real-time RT-PCR assay, as well as testosterone-induced AR protein levels in H1355 cells. benzylaminopurine 23-26 androgen receptor Homo sapiens 61-78 15041469-3 2004 Treatment with 1microM BaP tremendously reduced constitutive androgen receptor (AR) expression, as determined with Western immunoblotting and the real-time RT-PCR assay, as well as testosterone-induced AR protein levels in H1355 cells. benzylaminopurine 23-26 androgen receptor Homo sapiens 80-82 15041469-3 2004 Treatment with 1microM BaP tremendously reduced constitutive androgen receptor (AR) expression, as determined with Western immunoblotting and the real-time RT-PCR assay, as well as testosterone-induced AR protein levels in H1355 cells. benzylaminopurine 23-26 androgen receptor Homo sapiens 202-204 15041469-4 2004 Similarly, 1microM BaP significantly reduced AR mRNA levels in human bronchial epithelial cells BEAS-2B. benzylaminopurine 19-22 androgen receptor Homo sapiens 45-47 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 aryl hydrocarbon receptor Homo sapiens 92-117 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 aryl hydrocarbon receptor Homo sapiens 119-122 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 152-170 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 172-178 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 184-191 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 193-199 15041469-5 2004 Although BaP, 2,3,7,8-tetrachlorodibenzo-p-dixin and polychlorinated biphenyl 126 activated aryl hydrocarbon receptor (AhR), which subsequently induced cytochrome P4501A1 (CYP1A1) and P4501B1 (CYP1B1) expression in H1355 cells, unexpectedly, neither TCDD nor PCB126 reduced AR expression. benzylaminopurine 9-12 androgen receptor Homo sapiens 274-276 15060132-5 2004 Biochemical analysis established that Drosophila contains two distinct BRM complexes: (i) the BAP complex, defined by the presence of OSA and the absence of Polybromo and BAP170, and (ii) the PBAP complex, containing Polybromo and BAP170 but lacking OSA. benzylaminopurine 94-97 brahma Drosophila melanogaster 71-74 15130437-1 2004 OBJECTIVE: To investigate the effects of mitogen activated protein kinase (MAPK) signal transduction pathways on heat shock protein 70 (HSP70) gene expression in endothelial cells exposed to benzo(a)pryene (BaP). benzylaminopurine 207-210 heat shock protein family A (Hsp70) member 4 Homo sapiens 113-134 15130437-1 2004 OBJECTIVE: To investigate the effects of mitogen activated protein kinase (MAPK) signal transduction pathways on heat shock protein 70 (HSP70) gene expression in endothelial cells exposed to benzo(a)pryene (BaP). benzylaminopurine 207-210 heat shock protein family A (Hsp70) member 4 Homo sapiens 136-141 15130437-3 2004 RESULTS: The three phosphorylated MAPKs expressional levels especially p-ERK1 had different extents of changes with dose-response relationship under BaP exposure. benzylaminopurine 149-152 mitogen-activated protein kinase 3 Homo sapiens 73-77 15130437-4 2004 BaP inhibited the expression of HSP70, which significantly decreased in medium and high dose group (>or= 1.0 micro mol/L) but did not decrease in control group (P < 0.05). benzylaminopurine 0-3 heat shock protein family A (Hsp70) member 4 Homo sapiens 32-37 15130437-5 2004 Although the inhibitor of ERK (PD98059) could partly weaken the inhibited effects of BaP on HSP70 expression, HSP70 expression levels of endothelial cells pre-treated with PD98059 were still significantly lower than that of control cells (P < 0.05). benzylaminopurine 85-88 mitogen-activated protein kinase 1 Homo sapiens 26-29 15130437-5 2004 Although the inhibitor of ERK (PD98059) could partly weaken the inhibited effects of BaP on HSP70 expression, HSP70 expression levels of endothelial cells pre-treated with PD98059 were still significantly lower than that of control cells (P < 0.05). benzylaminopurine 85-88 heat shock protein family A (Hsp70) member 4 Homo sapiens 92-97 15130437-5 2004 Although the inhibitor of ERK (PD98059) could partly weaken the inhibited effects of BaP on HSP70 expression, HSP70 expression levels of endothelial cells pre-treated with PD98059 were still significantly lower than that of control cells (P < 0.05). benzylaminopurine 85-88 heat shock protein family A (Hsp70) member 4 Homo sapiens 110-115 15130437-6 2004 CONCLUSION: ERK1 pathway might play some roles in HSP70 gene expression in endothelial cells exposed to BaP, and other unknown signal pathways might also have some effects on this process. benzylaminopurine 104-107 mitogen-activated protein kinase 3 Homo sapiens 12-16 15130437-6 2004 CONCLUSION: ERK1 pathway might play some roles in HSP70 gene expression in endothelial cells exposed to BaP, and other unknown signal pathways might also have some effects on this process. benzylaminopurine 104-107 heat shock protein family A (Hsp70) member 4 Homo sapiens 50-55 15221496-9 2004 Individual changes in TNF-alpha levels showed a moderate negative correlation with the individual changes in BAP and OCL levels (r = -0.550 [P = 0.001], and r = -0.497 [P = 0.004], respectively). benzylaminopurine 109-112 tumor necrosis factor Homo sapiens 22-31 12616185-11 2003 MT I/II transcript was observed in HOK16B, which was further elevated in HOK16B-Bap-T. Retrospective analysis showed that high immunoreactivity to MT I/II in surgically resected laryngeal cancer specimen correlated with increased frequency of recurrence within 2 years of surgery. benzylaminopurine 80-83 metallothionein 3 Homo sapiens 0-7 12616185-11 2003 MT I/II transcript was observed in HOK16B, which was further elevated in HOK16B-Bap-T. Retrospective analysis showed that high immunoreactivity to MT I/II in surgically resected laryngeal cancer specimen correlated with increased frequency of recurrence within 2 years of surgery. benzylaminopurine 80-83 metallothionein 3 Homo sapiens 147-154 12792991-5 2003 It was suggested that BaP restrained proliferative activities of porcine aortic endothelial cells, which may be related to the inhibition of HSP70 expression by BaP. benzylaminopurine 161-164 heat shock protein family A (Hsp70) member 4 Homo sapiens 141-146 12898648-10 2003 Incubation of [(3)H]-BaP-3-beta-D-glucuronide (BaP-3G) with hemoglobin and beta-glucuronidase resulted in greater binding to hemoglobin than incubation with [(3)H]-3-OHBaP alone. benzylaminopurine 21-24 beta-glucuronidase Bos taurus 75-93 12663125-4 2003 The circulating level of leptin directly correlated with body mass index (BMI) (r=0.61-0.78, P<0.001) and was modestly, but significantly and positively associated with bAP activity (r=0.24-0.33, P<0.01) in the sera of men and women after adjustment for BMD, age and BMI. benzylaminopurine 172-175 leptin Homo sapiens 25-31 12663125-5 2003 The association of circulating leptin levels with bAP, a specific marker of osteoblast activity suggests that leptin levels influence osteoblast activity in vivo in elderly women and men. benzylaminopurine 50-53 leptin Homo sapiens 31-37 12610223-3 2003 180 kDa was photoaffinity-labeled with 8-azido-[alpha-(32)P]ATP in the T. minus cells in the presence of vanadate, which was specifically induced by the addition of benzyladenine in a similar manner as the induction of berberine biosynthesis in these cell cultures, whereas three bands were observed in the C. japonica cells in the size region between 120 and 150 kDa corresponding to full-sized ABC protein. benzylaminopurine 165-178 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 396-399 12610223-4 2003 The benzyladenine-induced band in T. minus showed properties similar to those of human MDR1, including the recognition of berberine, which suggests that the ABC protein detected in T. minus takes this endogenous alkaloid as a putative substrate for transport. benzylaminopurine 4-17 ATP binding cassette subfamily B member 1 Homo sapiens 87-91 12610223-4 2003 The benzyladenine-induced band in T. minus showed properties similar to those of human MDR1, including the recognition of berberine, which suggests that the ABC protein detected in T. minus takes this endogenous alkaloid as a putative substrate for transport. benzylaminopurine 4-17 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 157-160 12481063-9 2002 Levels of ACR3 and ACR4 mRNA are increased by treatment with benzyladenine. benzylaminopurine 61-74 ACT domain repeat 3 Arabidopsis thaliana 10-14 12481063-9 2002 Levels of ACR3 and ACR4 mRNA are increased by treatment with benzyladenine. benzylaminopurine 61-74 ACT domain repeat 4 Arabidopsis thaliana 19-23 11673620-1 2001 Regulation of expression of 1-aminocyclopropane-1-carboxylate (ACC) oxidase (VR-ACO1) and ACC synthase (VR-ACS1) genes by ethylene, indole-3-acetic acid (IAA), and N(6)-benzyladenine (BA), was investigated in mungbean hypocotyl tissues. benzylaminopurine 164-182 aconitase 1 Homo sapiens 80-84 12376653-5 2002 In addition to MeJA and indole-3-acetic acid (IAA), axr1-24 had decreased sensitivity to 1-aminocyclopropane-1-carboxylic acid, 6-benzylamino-purine, epi-brassinolide, and abscisic acid. benzylaminopurine 128-148 NAD(P)-binding Rossmann-fold superfamily protein Arabidopsis thaliana 52-56 12060247-0 2002 Inhibitory effects of elevated endogenous cytokinins on nitrate reductase in ipt-expressing tobacco are eliminated by short-term exposure to benzyladenine. benzylaminopurine 141-154 Ipt Agrobacterium tumefaciens 77-80 12060247-9 2002 We were able to restore wild-type levels of NRA in ipt-expressing plants by simultaneous induction of NR with BA and nitrate. benzylaminopurine 110-112 Ipt Agrobacterium tumefaciens 51-54 12010467-5 2002 Since APT also has a possible role in the interconversion of cytokinin bases to nucleotides, we characterized the activity of each isoform on zeatin, isopentenyladenine and benzyladenine. benzylaminopurine 173-186 adenine phosphoribosyltransferase Arabidopsis thaliana 6-9 32688728-7 2002 Synthetic indoleacetic acid and benzyladenine (1 and 5 muM) also inhibited the number of nodules per plant, and the magnitude of inhibition was greater in the normally-nodulating Williams 82 cultivar than in the NOD1-3 hypernodulating mutant. benzylaminopurine 32-45 NOD3 Glycine max 212-218 11782642-13 2002 BAP significantly (P < 0.05) increased 7.1% for the HEX group. benzylaminopurine 0-3 hematopoietically expressed homeobox Homo sapiens 55-58 11826984-7 2001 The Kd of solublized recombinant OLP to BA obtained from a Scatchard plot was 1.10 x 10(-6) M, which was similar to the Kd of CBP2 to BA (1.08 x 10(-6) M). benzylaminopurine 40-42 osmotin-like protein Nicotiana tabacum 33-36 11846329-6 2001 Serum levels of 1,25(OH)2D3 (p<0.01) and PTH (p<0.01) were negatively correlated with disease activity, the excretion of urinary pyridinium crosslinks showed a positive correlation with disease activity (p<0.01), and 1,25(OH)2D3 and PTH were positively correlated with bAP (p<0.01). benzylaminopurine 278-281 parathyroid hormone Homo sapiens 44-47 11673620-1 2001 Regulation of expression of 1-aminocyclopropane-1-carboxylate (ACC) oxidase (VR-ACO1) and ACC synthase (VR-ACS1) genes by ethylene, indole-3-acetic acid (IAA), and N(6)-benzyladenine (BA), was investigated in mungbean hypocotyl tissues. benzylaminopurine 164-182 acyl-CoA synthetase long chain family member 1 Homo sapiens 107-111 11673620-1 2001 Regulation of expression of 1-aminocyclopropane-1-carboxylate (ACC) oxidase (VR-ACO1) and ACC synthase (VR-ACS1) genes by ethylene, indole-3-acetic acid (IAA), and N(6)-benzyladenine (BA), was investigated in mungbean hypocotyl tissues. benzylaminopurine 184-186 aconitase 1 Homo sapiens 80-84 11673620-1 2001 Regulation of expression of 1-aminocyclopropane-1-carboxylate (ACC) oxidase (VR-ACO1) and ACC synthase (VR-ACS1) genes by ethylene, indole-3-acetic acid (IAA), and N(6)-benzyladenine (BA), was investigated in mungbean hypocotyl tissues. benzylaminopurine 184-186 acyl-CoA synthetase long chain family member 1 Homo sapiens 107-111 11673620-6 2001 In addition, BA abolished ethylene responsiveness with respect to expression of VR-ACO1 and VR-ACS1. benzylaminopurine 13-15 aconitase 1 Homo sapiens 83-87 11673620-6 2001 In addition, BA abolished ethylene responsiveness with respect to expression of VR-ACO1 and VR-ACS1. benzylaminopurine 13-15 acyl-CoA synthetase long chain family member 1 Homo sapiens 95-99 11673620-7 2001 Based on these results, we suggest that IAA and BA inhibit ethylene action, resulting in suppression of VR-ACO1 expression and induction of VR-ACS1 expression. benzylaminopurine 48-50 aconitase 1 Homo sapiens 107-111 11673620-7 2001 Based on these results, we suggest that IAA and BA inhibit ethylene action, resulting in suppression of VR-ACO1 expression and induction of VR-ACS1 expression. benzylaminopurine 48-50 acyl-CoA synthetase long chain family member 1 Homo sapiens 143-147 11577198-6 2001 Here we further show that AHK4 is a primary receptor that directly binds a variety of natural and synthetic cytokinins (e.g. not only N(6)-substituted aminopurines such as isopentenyl-adenine, trans-zeatin, benzyl-adenine, but also diphenylurea derivatives such as thidiazuron), in a highly specific manner (K(d) = 4.55+/-0.48x10(-9) M). benzylaminopurine 207-221 CHASE domain containing histidine kinase protein Arabidopsis thaliana 26-30 10077343-6 1999 A stronger correlation was found between PTH and circulating bone remodeling markers (r = 0.66 for osteocalcin, r = 0.56 for BAP, and r = 0.39 for ICTP). benzylaminopurine 125-128 parathyroid hormone Homo sapiens 41-44 11076769-3 2000 In the mesoderm, Wg and Slp activities are crucial for the suppression of bagpipe (bap), and hence visceral mesoderm formation, and the promotion of somatic muscle and heart formation within the anterior portion of each parasegment. benzylaminopurine 83-86 sloppy paired 1 Drosophila melanogaster 24-27 11822819-9 2001 The introduction of the synthetic ECM, crystallized GLP-1, and Hb-C into a BAP may provide a basis for designing a compact and rechargeable BAP (macrocapsule). benzylaminopurine 75-78 glucagon Homo sapiens 52-57 11207609-4 2000 The cytoplasmic tail of human TGN46 also determines ER localization of BAP chimeras in the parasite, but this can be overcome by the addition at the C-terminus of the tail of an acidic patch, which functions as an ER export signal in conjunction with an upstream tyrosine motif. benzylaminopurine 71-74 trans-golgi network protein 2 Homo sapiens 30-35 9783546-14 1998 BAP was higher in the untreated group (p = 0.005) and correlated with IL-alpha/IL-1ra in the whole group (r = 0.49, p = 0.03). benzylaminopurine 0-3 interleukin 1 receptor type 1 Homo sapiens 79-85 10663349-10 1999 It is concluded that: (1) patients with AN have a high degree of osteopenia which correlated with bAP levels; (2) urinary CTX fragments found in AN patients seem to come mainly from old bone (beta-CTX), while CTX found in healthy adolescent control females come from new bone (alpha-CTX). benzylaminopurine 98-101 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 122-125 9858947-12 1998 However, V(III)-complex exerted much more potent effects than the other treatments, significantly prolonging mean survival time, retarding tumor growth rate and decreasing the carcinogenic potency of BaP in the TR-3 group, in comparison to the control and the TR-1 and TR-2 groups. benzylaminopurine 200-203 thioredoxin reductase 2 Rattus norvegicus 211-215 9577752-8 1998 Conventional and CRM asphalt worker airborne exposures to the PAH carcinogen marker, BaP, were very low with concentrations comparable to ambient air in many cities. benzylaminopurine 85-88 phenylalanine hydroxylase Homo sapiens 62-65 9501142-1 1998 cytokinin-induced nitrate reductase activity is correlated with increased nia1 transcription and mrna levels Nitrate reductase (NR) activity increased up to 14-fold in response to treatment of Arabidopsis thaliana seedlings with the cytokinin benzyladenine. NR induction was observed in seedlings germinated directly on cytokinin-containing medium, seedlings transferred to cytokinin medium, and seedlings grown in soil in which cytokinin was applied directly to the leaves. benzylaminopurine 244-257 nitrate reductase 1 Arabidopsis thaliana 18-35 9501142-1 1998 cytokinin-induced nitrate reductase activity is correlated with increased nia1 transcription and mrna levels Nitrate reductase (NR) activity increased up to 14-fold in response to treatment of Arabidopsis thaliana seedlings with the cytokinin benzyladenine. NR induction was observed in seedlings germinated directly on cytokinin-containing medium, seedlings transferred to cytokinin medium, and seedlings grown in soil in which cytokinin was applied directly to the leaves. benzylaminopurine 244-257 nitrate reductase 1 Arabidopsis thaliana 19-36 9501142-1 1998 cytokinin-induced nitrate reductase activity is correlated with increased nia1 transcription and mrna levels Nitrate reductase (NR) activity increased up to 14-fold in response to treatment of Arabidopsis thaliana seedlings with the cytokinin benzyladenine. NR induction was observed in seedlings germinated directly on cytokinin-containing medium, seedlings transferred to cytokinin medium, and seedlings grown in soil in which cytokinin was applied directly to the leaves. benzylaminopurine 244-257 nitrate reductase 1 Arabidopsis thaliana 129-131 9501142-2 1998 About the same level of induction was seen in both wild-type and Nia2-deletion mutants, indicating that increased NR activity is related to the expression of the minor NR gene, Nia1. The steady-state Nia1 mRNA level was increased severalfold in both wild-type and mutant seedlings after benzyladenine treatment. benzylaminopurine 288-301 nitrate reductase 1 Arabidopsis thaliana 115-117 9501142-2 1998 About the same level of induction was seen in both wild-type and Nia2-deletion mutants, indicating that increased NR activity is related to the expression of the minor NR gene, Nia1. The steady-state Nia1 mRNA level was increased severalfold in both wild-type and mutant seedlings after benzyladenine treatment. benzylaminopurine 288-301 nitrate reductase 1 Arabidopsis thaliana 201-205 9613848-7 1998 Specific agglutination of D positive red cells by D10 scFv-BAP was enhanced in the presence of anti-BAP antibody, suggesting that further multimerization of scFv led to highly efficient cell agglutination. benzylaminopurine 59-62 immunglobulin heavy chain variable region Homo sapiens 54-58 9613848-7 1998 Specific agglutination of D positive red cells by D10 scFv-BAP was enhanced in the presence of anti-BAP antibody, suggesting that further multimerization of scFv led to highly efficient cell agglutination. benzylaminopurine 59-62 immunglobulin heavy chain variable region Homo sapiens 157-161 9613848-7 1998 Specific agglutination of D positive red cells by D10 scFv-BAP was enhanced in the presence of anti-BAP antibody, suggesting that further multimerization of scFv led to highly efficient cell agglutination. benzylaminopurine 100-103 immunglobulin heavy chain variable region Homo sapiens 54-58 9613848-7 1998 Specific agglutination of D positive red cells by D10 scFv-BAP was enhanced in the presence of anti-BAP antibody, suggesting that further multimerization of scFv led to highly efficient cell agglutination. benzylaminopurine 100-103 immunglobulin heavy chain variable region Homo sapiens 157-161 9613848-8 1998 By grafting BAP enzymatic activity into the scFv fragment (enzyme-linked scFv), blood typing could conveniently be performed. benzylaminopurine 12-15 immunglobulin heavy chain variable region Homo sapiens 44-48 9613848-8 1998 By grafting BAP enzymatic activity into the scFv fragment (enzyme-linked scFv), blood typing could conveniently be performed. benzylaminopurine 12-15 immunglobulin heavy chain variable region Homo sapiens 73-77 9464317-2 1998 In this study, we examined the types of mutations produced by the primary nitroreduced metabolites, 1-, 3-, and 6-nitroso-BaP (NO-BaP) in the hprt gene of Chinese hamster ovary cells. benzylaminopurine 122-125 hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus 142-146 9562963-3 1998 Compared to BAP-p53, the BAP-TSPf group had a similar antitumor efficacy. benzylaminopurine 12-15 tumor protein p53 Homo sapiens 16-19 9562963-4 1998 More importantly, liposomes complexed with BAP-TSPf and BAP-p53 synergistically decreased the growth of MDA-MB-435 tumors when compared to either BAP-p53 or BAP-TSPf alone. benzylaminopurine 43-46 tumor protein p53 Homo sapiens 150-153 9562963-4 1998 More importantly, liposomes complexed with BAP-TSPf and BAP-p53 synergistically decreased the growth of MDA-MB-435 tumors when compared to either BAP-p53 or BAP-TSPf alone. benzylaminopurine 56-59 tumor protein p53 Homo sapiens 60-63 9562963-4 1998 More importantly, liposomes complexed with BAP-TSPf and BAP-p53 synergistically decreased the growth of MDA-MB-435 tumors when compared to either BAP-p53 or BAP-TSPf alone. benzylaminopurine 56-59 tumor protein p53 Homo sapiens 150-153 9562963-4 1998 More importantly, liposomes complexed with BAP-TSPf and BAP-p53 synergistically decreased the growth of MDA-MB-435 tumors when compared to either BAP-p53 or BAP-TSPf alone. benzylaminopurine 56-59 tumor protein p53 Homo sapiens 60-63 9562963-4 1998 More importantly, liposomes complexed with BAP-TSPf and BAP-p53 synergistically decreased the growth of MDA-MB-435 tumors when compared to either BAP-p53 or BAP-TSPf alone. benzylaminopurine 56-59 tumor protein p53 Homo sapiens 150-153 9219428-0 1996 Cucumber chloroplast trnL(CAA) gene: nucleotide sequence and in vivo expression analysis in etiolated cucumber seedlings treated with benzyladenine and light. benzylaminopurine 134-147 trnL Cucumis sativus 21-25 9375416-4 1997 The frequently used cytokinin N6-benzyladenine was conjugated to glucuronic acid at N-3 or at N-9 but only the former was a substrate for GUS. benzylaminopurine 30-46 glucuronidase beta Homo sapiens 138-141 9390429-9 1997 However, application of the cytokinin 6-benzylaminopurine induces ectopic expression of CER2-GUS in all cell types of leaves that emerge following treatment. benzylaminopurine 38-57 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 88-92 9002604-4 1996 Analysis of CAT activity in leaf tissues showed that mechanical wounding increased the rpL34 promoter activity about 5 times as compared to untreated controls and that the promoter activity was further enhanced by plant growth regulators, 2,4-dichlorophenoxyacetic acid and benzyladenine. benzylaminopurine 274-287 ribosomal protein L34 Rattus norvegicus 87-92 8942941-17 1996 A bAP > 20 ng/ml had a sensitivity of 56%, specificity of 92% and positive predictive value of 80% in the prediction of an PTH higher than > 400 pg/ml and therefore of the biological diagnosis of hyperparathyroidism. benzylaminopurine 2-5 parathyroid hormone Homo sapiens 126-129