PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2809201-8	1989	Thioglycollate-elicited PM with highest endogenous C1q levels were unaffected by exogenous C1q, whereas oil-elicited PM with intermediate C1q levels were slightly augmented in their ADCC response by exogenous C1q.	Thioglycolates	0-14	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	51-54
2584931-1	1989	A cDNA encoding the Mac-2 antigen, a surface marker highly expressed by thioglycollate-elicited macrophages, has been cloned by immunoscreening of a lambda gt11-P388D1 expression library.	Thioglycolates	72-86	galectin 3	Rattus norvegicus	20-33
2509612-1	1989	Thioglycollate-elicited macrophages from C3H/HeJ (Lpsd) and C3H/OuJ (Lpsn) mice were cultured in a two-signal, tumoricidal assay using recombinant interferon-gamma (rIFN-gamma) as the "priming" signal and recombinant human C5a (rC5a) as the "trigger" signal.	Thioglycolates	0-14	interferon gamma	Mus musculus	147-163
2509612-1	1989	Thioglycollate-elicited macrophages from C3H/HeJ (Lpsd) and C3H/OuJ (Lpsn) mice were cultured in a two-signal, tumoricidal assay using recombinant interferon-gamma (rIFN-gamma) as the "priming" signal and recombinant human C5a (rC5a) as the "trigger" signal.	Thioglycolates	0-14	interferon gamma	Rattus norvegicus	165-175
2509612-1	1989	Thioglycollate-elicited macrophages from C3H/HeJ (Lpsd) and C3H/OuJ (Lpsn) mice were cultured in a two-signal, tumoricidal assay using recombinant interferon-gamma (rIFN-gamma) as the "priming" signal and recombinant human C5a (rC5a) as the "trigger" signal.	Thioglycolates	0-14	complement C5a receptor 1	Homo sapiens	223-226
2809211-7	1989	Peak SAP mRNA concentrations were observed 8 h after thioglycollate and 12 to 18 h after azocasein injection; by 36 h concentrations were close to preinflammatory levels.	Thioglycolates	53-67	amyloid P component, serum	Mus musculus	5-8
2809211-8	1989	All mRNA species studied (SAP, SAA and the complement components C3, C5 and factor B) were induced more rapidly by the thioglycollate stimulus and reached higher peak concentrations.	Thioglycolates	119-133	amyloid P component, serum	Mus musculus	26-29
2809211-8	1989	All mRNA species studied (SAP, SAA and the complement components C3, C5 and factor B) were induced more rapidly by the thioglycollate stimulus and reached higher peak concentrations.	Thioglycolates	119-133	serum amyloid A cluster	Mus musculus	31-34
2809211-8	1989	All mRNA species studied (SAP, SAA and the complement components C3, C5 and factor B) were induced more rapidly by the thioglycollate stimulus and reached higher peak concentrations.	Thioglycolates	119-133	hemolytic complement	Mus musculus	69-84
2809211-9	1989	SAP mRNA levels were correlated with other parameters of inflammation: infiltration of peritoneal exudate cells (PEC) into the peritoneum after thioglycollate injection, and serum concentrations of SAP after azocasein injection.	Thioglycolates	144-158	amyloid P component, serum	Mus musculus	0-3
2809211-11	1989	The highest numbers of PEC were present 24 h after the thioglycollate stimulus, i.e. 16 h after the maximum SAP mRNA concentration, indicating the continuation of an active local inflammation many hours after one aspect of the systemic response has ceased.	Thioglycolates	55-69	amyloid P component, serum	Mus musculus	108-111
2501392-1	1989	Thioglycollate-elicited murine peritoneal macrophages produce significant quantities of TNF 2 to 4 h after induction with bacterial endotoxin, LPS.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	88-91
2551961-1	1989	The effect of murine rTNF-alpha on the binding of human 125I-rCSF-1 to murine thioglycolate-elicited peritoneal exudate macrophages (PEM) was investigated.	Thioglycolates	78-91	tumor necrosis factor	Rattus norvegicus	21-31
2551961-1	1989	The effect of murine rTNF-alpha on the binding of human 125I-rCSF-1 to murine thioglycolate-elicited peritoneal exudate macrophages (PEM) was investigated.	Thioglycolates	78-91	colony stimulating factor 1	Rattus norvegicus	61-67
2477479-1	1989	ApoE synthesis and secretion, as a function of cellular cholesterol content and cholesterol efflux, was studied in thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	115-128	apolipoprotein E	Mus musculus	0-4
2477479-0	1989	Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: effect of cholesterol efflux.	Thioglycolates	35-48	apolipoprotein E	Mus musculus	27-31
2926328-3	1989	In the present study using mouse serum-induced thioglycollate-elicited peritoneal M phi (TPM) as a model system for SER expression, mAb SER-4 IgG2a completely blocked rosette formation at 1 microgram/ml.	Thioglycolates	47-61	immunoglobulin heavy variable V1-9	Mus musculus	142-147
2917136-6	1989	L-CM enhanced LPL secretion by thioglycollate-elicited peritoneal macrophages and had no effect on LPL secretion by resident peritoneal macrophages.	Thioglycolates	31-45	lipoprotein lipase	Mus musculus	14-17
2654009-3	1989	Flow cytometric analysis of monoclonal antibody (mAb)-labeled thioglycollate-elicited peritoneal, and resident splenic, M phi showed a tumor-induced shift of Mac-1, -2, -3, and Ia antigen expression.	Thioglycolates	62-76	integrin subunit alpha M	Homo sapiens	158-163
2915994-6	1989	Thioglycollate-induced macrophages exposed to HRP, bovine lactoperoxidase, or human myeloperoxidase demonstrated enhanced secretion of TNF.	Thioglycolates	0-14	tumor necrosis factor	Homo sapiens	135-138
2915994-7	1989	When exposed to HRP, both resident and thioglycollate-induced macrophages secreted significant amounts of TNF and acquired the ability to lyse 3T12 cells.	Thioglycolates	39-53	tumor necrosis factor	Mus musculus	106-109
2904439-2	1988	Cytoplasmic pH (pHi) regulation was studied in thioglycolate-elicited murine macrophages using fluorescent probes.	Thioglycolates	47-60	glucose-6-phosphate isomerase 1	Mus musculus	16-19
2720790-3	1989	Both thioglycollate-elicited peritoneal macrophages and the normal macrophages cloned from our JBM phi 1.1 bone-marrow-derived cell line effectively produced TNF at levels similar to, or higher than, those obtained in the presence of high concentrations of lipopolysaccharide (LPS).	Thioglycolates	5-19	tumor necrosis factor	Mus musculus	158-161
2786047-3	1989	Thioglycollate-elicited peritoneal exudate cells were observed to release a considerable amount of Fn during the adherence procedure for macrophage purification.	Thioglycolates	0-14	fibronectin 1	Rattus norvegicus	99-101
2523953-2	1989	Human fibronectin receptor (VLA-5) alpha and beta chain probes were used to identify their mouse homologues in a thioglycollate-elicited peritoneal exudate cell cDNA library.	Thioglycolates	113-127	fibronectin 1	Mus musculus	6-17
2523953-6	1989	Analysis of levels of expression comparing resting peritoneal macrophages with macrophages elicited using inflammatory stimuli indicated that alpha chain message and surface VLA-5 expression were significantly increased using thioglycollate or Listeria monocytogenes as stimuli to elicit cells.	Thioglycolates	226-240	integrin alpha 5 (fibronectin receptor alpha)	Mus musculus	174-179
2701577-7	1989	In contrast with marrow M phi, thioglycollate-elicited peritoneal M phi, which normally release only small quantities of PGE2, showed over 5-fold increases in PGE2 production following treatment with IFN gamma, IFN alpha/beta, or TNF, but not with other cytokines or mouse serum.	Thioglycolates	31-45	interferon gamma	Mus musculus	200-209
2701577-7	1989	In contrast with marrow M phi, thioglycollate-elicited peritoneal M phi, which normally release only small quantities of PGE2, showed over 5-fold increases in PGE2 production following treatment with IFN gamma, IFN alpha/beta, or TNF, but not with other cytokines or mouse serum.	Thioglycolates	31-45	interferon alpha	Mus musculus	211-220
2701577-7	1989	In contrast with marrow M phi, thioglycollate-elicited peritoneal M phi, which normally release only small quantities of PGE2, showed over 5-fold increases in PGE2 production following treatment with IFN gamma, IFN alpha/beta, or TNF, but not with other cytokines or mouse serum.	Thioglycolates	31-45	tumor necrosis factor	Mus musculus	230-233
2707186-5	1989	Thioglycollate-induced activated mouse peritoneal macrophages secreted significantly less fibronectin than resident peritoneal macrophages, a finding contrasting with those of Tsukamoto et al.	Thioglycolates	0-14	fibronectin 1	Mus musculus	90-101
2521349-5	1989	Thioglycollate, proteose-peptone, or IL-1 elicited peritoneal exudate cells were found to bind 125I-IL-1 alpha in a specific and saturable manner.	Thioglycolates	0-14	interleukin 1 alpha	Homo sapiens	100-110
2484638-11	1989	The in vitro incubation of thioglycollate-elicited peritoneal macrophages with swainsonine consistently resulted in levels of activation (6- to 8-fold) comparable to that obtained by treatment with known in vitro macrophage activating agents such as lipopolysaccharide (LPS) or recombinant gamma-interferon (rIFN-gamma).	Thioglycolates	27-41	interferon gamma	Rattus norvegicus	308-318
3196726-1	1988	Thioglycollate-elicited mouse peritoneal macrophages spontaneously secrete lipoprotein lipase during culture.	Thioglycolates	0-14	lipoprotein lipase	Mus musculus	75-93
3167093-2	1988	Mouse peritoneal macrophages, induced by previous intraperitoneal injections of 3% thioglycollate, were labelled in vitro by their exposure to immune complexes of 59Fe-transferrin-antitransferrin antibody.	Thioglycolates	83-97	transferrin	Mus musculus	168-179
3262711-2	1988	We have identified conditions whereby thioglycollate-elicited macrophages become stimulatory, but primarily for the CD8+ T cell subset.	Thioglycolates	38-52	CD8a molecule	Homo sapiens	116-119
2457619-2	1988	rIFN gamma acted in synergy with suboptimal levels of bacterial LPS by priming thioglycollate-induced mouse peritoneal exudate cells (TG-PEC) to express high levels of surface procoagulant.	Thioglycolates	79-93	toll-like receptor 4	Mus musculus	64-67
3194151-3	1988	In the presence of thioglycollate-elicited peritoneal exudate cells, the opposite effect was seen and TNF enhanced the growth of trypanosomes in vitro.	Thioglycolates	19-33	tumor necrosis factor	Homo sapiens	102-105
3112228-5	1987	Bone marrow-derived macrophages do not produce detectable PAI, whereas inflammatory macrophages obtained from thioglycollate-induced peritoneal exudates produce only low levels of PAI.	Thioglycolates	110-124	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	180-183
3042043-4	1988	GM-CSF significantly increased phorbol myristate acetate- and zymosan-elicited H2O2 release by resident and thioglycollate-elicited macrophages after 48 hours in vitro.	Thioglycolates	108-122	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-6
3042043-6	1988	GM-CSF also stimulated Fc-dependent phagocytosis by peritoneal macrophages, although the stimulation of resident macrophages (1.4-fold) was less dramatic than that of thioglycollate-elicited cells (2.1-fold).	Thioglycolates	167-181	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-6
3379311-8	1988	We have identified bFGF in extracts of adherent thioglycollate-stimulated mouse peritoneal macrophages by immunological criteria including the ability of the extract to compete with 125I-bFGF for binding to affinity-purified anti-human bFGF antibodies in the RIA and the ability of these antibodies in inhibit the bFGF-like biological activity of the macrophage extract.	Thioglycolates	48-62	fibroblast growth factor 2	Mus musculus	19-23
3163717-4	1988	Murine thioglycollate-elicited PMN which were treated with recombinant human TNF demonstrated augmented killing of L. pneumophila bacteria in vitro.	Thioglycolates	7-21	tumor necrosis factor	Homo sapiens	77-80
3257249-1	1988	The fusion of thioglycollate-elicited peritoneal macrophages from the lipopolysaccharide (LPS)-nonresponsive C3H/HeJ mouse strain to a hypoxanthine phosphoribosyltransferase (HPRT)-negative variant of the murine macrophage cell line P388D1 has resulted in the derivation of eight hybrid clones following HAT selection.	Thioglycolates	14-28	hypoxanthine guanine phosphoribosyl transferase	Mus musculus	135-173
3257249-1	1988	The fusion of thioglycollate-elicited peritoneal macrophages from the lipopolysaccharide (LPS)-nonresponsive C3H/HeJ mouse strain to a hypoxanthine phosphoribosyltransferase (HPRT)-negative variant of the murine macrophage cell line P388D1 has resulted in the derivation of eight hybrid clones following HAT selection.	Thioglycolates	14-28	hypoxanthine guanine phosphoribosyl transferase	Mus musculus	175-179
2449204-4	1988	Viral proteins conjugated to alpha 2M were taken up by thioglycolate-induced murine peritoneal exudate cells (PEC) more effectively than the free viral proteins.	Thioglycolates	55-68	alpha-2-macroglobulin	Mus musculus	29-37
3121748-2	1988	Thioglycolate-elicited peritoneal exudate macrophages from C3H/HeJ mice were rendered cytolytic for P815 mastocytoma cells in a two-signal tumoricidal assay that used recombinant interferon-gamma (rIFN-gamma; 1 to 10 U/ml) as a "priming" signal and butanol-extracted lipopolysaccharide (But-LPS; 0.1 to 5 micrograms/ml) as a "trigger" signal.	Thioglycolates	0-13	interferon gamma	Mus musculus	179-195
3121748-2	1988	Thioglycolate-elicited peritoneal exudate macrophages from C3H/HeJ mice were rendered cytolytic for P815 mastocytoma cells in a two-signal tumoricidal assay that used recombinant interferon-gamma (rIFN-gamma; 1 to 10 U/ml) as a "priming" signal and butanol-extracted lipopolysaccharide (But-LPS; 0.1 to 5 micrograms/ml) as a "trigger" signal.	Thioglycolates	0-13	interferon gamma	Rattus norvegicus	197-218
3202040-7	1988	It is conceivable, therefore, that the enhancing effect of TNF in vivo is mediated via a cell present in thioglycollate-induced peritoneal exudate, which mostly comprises macrophages.	Thioglycolates	105-119	tumor necrosis factor	Mus musculus	59-62
2960767-2	1987	Thioglycollate-elicited peritoneal M luminal diameter from normal and TBH BALB/c mice were modulated with anti-Mac-1, -2, or -3 monoclonal antibodies (mAb) or depleted with mAb plus complement and cultured in the presence or absence of indomethacin.	Thioglycolates	0-14	integrin alpha M	Mus musculus	111-116
3119764-4	1987	Elaboration of this protein was also diminished by macrophages that had been stimulated by thioglycollate in vivo, and treatment of these cells with LPS led to further decline.	Thioglycolates	91-105	toll-like receptor 4	Mus musculus	149-152
3108395-4	1987	In this communication, thioglycollate-elicited murine peritoneal macrophages were shown to express about 2300 high affinity (Ka approximately 2 X 10(10) M-1) BSF-1 receptors/cell.	Thioglycolates	23-37	interleukin 4	Mus musculus	158-163
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	interferon gamma	Mus musculus	81-90
3814130-2	1987	Secretion of lipoprotein lipase was 10-fold greater in thioglycollate-elicited and 6-fold greater in mineral oil-elicited macrophages.	Thioglycolates	55-69	lipoprotein lipase	Mus musculus	13-31
3346339-8	1988	Thioglycolate-elicited murine peritoneal macrophages demonstrated similar responses to epinephrine, met-enkephalin, and their combination.	Thioglycolates	0-13	pro-opiomelanocortin-alpha	Mus musculus	100-114
3610606-4	1987	However, treatment of thioglycollate-elicited PEC with interferon-gamma induced cytotoxic activity in PEC obtained from DMN-exposed animals but not in PEC obtained from control animals.	Thioglycolates	22-36	interferon gamma	Mus musculus	55-71
3610606-8	1987	Likewise, thioglycollate-elicited PEC from DMN-exposed mice had dose-related decreases in mTFR expression and total transferrin-binding activity, suggesting a change in their state of activation.	Thioglycolates	10-24	transferrin receptor	Mus musculus	90-94
3610606-8	1987	Likewise, thioglycollate-elicited PEC from DMN-exposed mice had dose-related decreases in mTFR expression and total transferrin-binding activity, suggesting a change in their state of activation.	Thioglycolates	10-24	transferrin	Mus musculus	116-127
3549950-1	1987	An anti-macrophage monoclonal antibody designated TRPM-3 was produced using thioglycollate-elicited rat peritoneal macrophages as immunogen.	Thioglycolates	76-90	transient receptor potential cation channel, subfamily M, member 3	Rattus norvegicus	50-56
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	tumor necrosis factor	Mus musculus	125-134
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	tumor necrosis factor	Mus musculus	158-167
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	interleukin 1 complex	Mus musculus	170-174
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	plasminogen activator, urokinase	Mus musculus	179-183
3097240-1	1986	Exposure of mouse resident and thioglycollate-elicited peritoneal macrophages to IFN-gamma leads to a marked increase in the TNF-alpha (tumor necrosis factor/cachectin), IL-1 and u-PA (urokinase-type plasminogen activator) mRNA levels.	Thioglycolates	31-45	plasminogen activator, urokinase	Mus musculus	185-221
3095245-4	1986	IFN-gamma treatment of resting macrophages and those activated or elicited by sodium caseinate, lipopolysaccharide, or Mycobacterium bovis BCG did not result in activation, as measured by hydrogen peroxide production; however, when thioglycolate was used as an eliciting agent, incubation with IFN-gamma resulted in a dramatic increase in hydrogen peroxide production compared with that by untreated controls.	Thioglycolates	232-245	interferon gamma	Mus musculus	0-9
3546281-2	1986	Macrophages from either normal or thioglycollate-primed mice continuously secreted LPL into the culture medium.	Thioglycolates	34-48	lipoprotein lipase	Mus musculus	83-86
3760571-1	1986	Expression of the c-fos, c-myc, and c-fms proto-oncogenes has been studied in thioglycollate-elicited murine peritoneal macrophages after exposure to lipopolysaccharide (LPS).	Thioglycolates	78-92	FBJ osteosarcoma oncogene	Mus musculus	18-23
3530505-2	1986	After intraperitoneal injection of Adriamycin, BCG or thioglycolate the ADCC of peritoneal cells toward antibody-coated SRBC was elevated to 30% in contrast to the ADCC of spleen cells.	Thioglycolates	54-67	caveolae associated 3	Mus musculus	120-124
3780044-2	1986	B10.A mice which have the ability to eliminate the parasites exhibited a greater capacity to recruit cells into the peritoneal cavity after thioglycollate injection, when compared to A/J mice.	Thioglycolates	140-154	granzyme C	Mus musculus	0-3
3754653-3	1986	Thioglycollate-elicited peritoneal macrophages obtained from mice contain a pool of cachectin mRNA that is not expressed as protein.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	84-93
3700467-2	1986	Using the Ca++-sensitive photoprotein aequorin we have measured intracellular free Ca++ ion concentration ([Ca++]i) in thioglycolate-elicited mouse peritoneal macrophages during phagocytosis and IgG-induced spreading.	Thioglycolates	119-132	carbonic anhydrase 1	Mus musculus	108-114
3697381-2	1986	The rate of iron release from thioglycollate-elicited mouse peritoneal macrophages pulsed with 59Fe-labelled transferrin-antitransferrin immune complexes was lower than that from resident or Corynebacterium parvum-activated macrophages.	Thioglycolates	30-44	transferrin	Mus musculus	109-120
3082977-2	1986	Treatment of thioglycollate-elicited, C57Bl/6 murine peritoneal macrophages with nanogram quantities of bacterial lipopolysaccharide (LPS) consistently results in altered 32Pi labeling of a specific set of proteins (e.g., proteins of 67, 37, 33, and 28 kD), as measured by autoradiography after SDS-polyacrylamide gel electrophoresis.	Thioglycolates	13-27	toll-like receptor 4	Mus musculus	134-137
2418957-2	1986	N-CWS also induced IFN-alpha/beta and IFN-gamma in the cultures of thioglycollate-elicited peritoneal cells.	Thioglycolates	67-81	interferon alpha	Mus musculus	19-28
2418957-2	1986	N-CWS also induced IFN-alpha/beta and IFN-gamma in the cultures of thioglycollate-elicited peritoneal cells.	Thioglycolates	67-81	interferon gamma	Mus musculus	38-47
2418957-3	1986	When induced with N-CWS, the mixed cultures of thioglycollate-elicited macrophages and spleen cells produced high titered IFN-gamma.	Thioglycolates	47-61	interferon gamma	Mus musculus	122-131
3510719-17	1986	Significant blastogenic proliferation was observed, and the supernatant of the culture was shown to be able to render thioglycollate-induced peritoneal macrophages of ACl rats cytotoxic to AMC-60 tumor cells, indicating that a certain cell population of the cell mixture produced a lymphokine(s) resembling macrophage activating factor (MAF) during the incubation.	Thioglycolates	118-132	MAF bZIP transcription factor	Rattus norvegicus	337-340
2424976-8	1986	Thioglycolate-elicited M phi had 75% less intracellular LZM than untreated resident M phi.	Thioglycolates	0-13	lysozyme	Homo sapiens	56-59
3721620-0	1986	Requirement for the continual presence of lipopolysaccharide for production of tumor necrosis factor by thioglycollate-induced peritoneal murine macrophages.	Thioglycolates	104-118	tumor necrosis factor	Mus musculus	79-100
3721620-1	1986	This work demonstrates the need for the continued presence of lipopolysaccharide (LPS) for tumor necrosis factor (TNF) production by thioglycollate-induced peritoneal macrophages.	Thioglycolates	133-147	tumor necrosis factor	Mus musculus	91-112
3721620-1	1986	This work demonstrates the need for the continued presence of lipopolysaccharide (LPS) for tumor necrosis factor (TNF) production by thioglycollate-induced peritoneal macrophages.	Thioglycolates	133-147	tumor necrosis factor	Mus musculus	114-117
3522317-2	1986	Thioglycolate-elicited peritoneal macrophages freshly isolated from insulin-deficient mice have increased activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is reflected in a greater rate of cholesterol synthesis by these macrophages.	Thioglycolates	0-13	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	Mus musculus	118-165
3522317-3	1986	In contrast, thioglycolate-elicited macrophages from control mice with diet-induced hypertriglyceridemia had normal levels of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.	Thioglycolates	13-26	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	Mus musculus	126-173
2934735-5	1985	Although all three isotypes were active in the antibody-dependent, macrophage-mediated cytotoxicity assay with murine thioglycolate-elicited macrophages, the IgG2a gave the highest percentage of lysis; similar results were obtained in the same assay with human monocytes as effector cells.	Thioglycolates	118-131	immunoglobulin heavy variable V1-9	Mus musculus	158-163
4079920-1	1985	Highly sensitive and specific synthetic substrates were used to quantitate cathepsin B and D activity in peritoneal macrophages in response to stimulation in vivo with mineral oil and thioglycollate.	Thioglycolates	184-198	cathepsin B	Homo sapiens	75-86
4079920-4	1985	Cathepsin D activity also increased significantly after both mineral oil and thioglycollate.	Thioglycolates	77-91	cathepsin D	Homo sapiens	0-11
4041474-9	1985	Phospholipase A1 was also released by thioglycollate-induced peritoneal macrophages.	Thioglycolates	38-52	lipase H	Homo sapiens	0-16
3844438-11	1985	In contrast, apolipoprotein E, another secreted protein of macrophages, was secreted by resident and thioglycollate-elicited macrophages but not by freshly harvested pyran copolymer-activated macrophages.	Thioglycolates	101-115	apolipoprotein E	Mus musculus	13-29
3862903-3	1985	The mechanism by which IgG2A from a syngeneic antitumor hyperimmune serum mediates destruction of target cells in the presence of thioglycollate-elicited peritoneal macrophages was investigated by using an in vitro assay system.	Thioglycolates	130-144	immunoglobulin heavy variable V1-9	Mus musculus	23-28
3923098-4	1985	LFA-1 could be induced in vitro on thioglycollate (TG)-elicited but not on proteose peptone (PP)-elicited or resident macrophages.	Thioglycolates	51-53	integrin alpha L	Mus musculus	0-5
4028171-3	1985	Activation of thioglycollate-stimulated C57BL/6 mouse peritoneal macrophages by macrophage activation factor (MAF) plus LPS, IFN-gamma plus LPS or the calcium ionophore, A23187, was inhibited in a dose-dependent fashion by the calcium channel blockers nifedipine and verapamil.	Thioglycolates	14-28	avian musculoaponeurotic fibrosarcoma oncogene homolog	Mus musculus	110-113
3897377-1	1985	The role of the complement receptor type 3 (CR3) on thioglycollate-elicited peritoneal macrophages (TG-PM) in the destruction of opsonized particles was studied.	Thioglycolates	52-66	integrin alpha M	Mus musculus	16-42
3897377-1	1985	The role of the complement receptor type 3 (CR3) on thioglycollate-elicited peritoneal macrophages (TG-PM) in the destruction of opsonized particles was studied.	Thioglycolates	52-66	integrin alpha M	Mus musculus	44-47
3871461-3	1985	In contrast, 2 pools of nude mouse sera and several pools of MS from thioglycollate-injected mice (TMS) used at 1% were consistently comparable with FCS at 5-10% in terms of in vitro generation of effector Tc cells and antibody secreting B cells.	Thioglycolates	69-83	thermosensitivity	Mus musculus	99-102
6619735-0	1983	Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages.	Thioglycolates	57-71	apolipoprotein E	Mus musculus	0-12
3923098-4	1985	LFA-1 could be induced in vitro on thioglycollate (TG)-elicited but not on proteose peptone (PP)-elicited or resident macrophages.	Thioglycolates	35-49	integrin alpha L	Mus musculus	0-5
3967899-2	1985	Gm-3.2 is found on all neutrophils in peritoneal exudates and in bone marrow, and is also present on macrophages activated by thioglycolate but is absent from lymphoid, kidney, liver, heart, and red cells.	Thioglycolates	126-139	granulocyte macrophage antigen 3	Mus musculus	0-4
2981092-1	1985	The number of transferrin receptors in thioglycollate-elicited murine peritoneal macrophages is markedly depressed after exposure to murine gamma-interferon (IFN gamma) in vitro.	Thioglycolates	39-53	transferrin	Mus musculus	14-25
2981092-1	1985	The number of transferrin receptors in thioglycollate-elicited murine peritoneal macrophages is markedly depressed after exposure to murine gamma-interferon (IFN gamma) in vitro.	Thioglycolates	39-53	interferon gamma	Mus musculus	140-156
2981092-1	1985	The number of transferrin receptors in thioglycollate-elicited murine peritoneal macrophages is markedly depressed after exposure to murine gamma-interferon (IFN gamma) in vitro.	Thioglycolates	39-53	interferon gamma	Mus musculus	158-167
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	30-44	transferrin	Mus musculus	147-158
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	30-44	transferrin	Mus musculus	235-246
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	30-44	interferon gamma	Mus musculus	370-379
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	46-48	transferrin	Mus musculus	147-158
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	46-48	transferrin	Mus musculus	235-246
2981092-4	1985	Saturation binding studies on thioglycollate (TG)-elicited peritoneal macrophages after exposure to A23187 or PMA showed the reduced expression of transferrin binding activity attributable to a decrease in the total number of cellular transferrin receptors and not an alteration in receptor-ligand affinity, in agreement with previous results obtained after exposure to IFN gamma.	Thioglycolates	46-48	interferon gamma	Mus musculus	370-379
6241933-2	1984	The destruction of ATPase activity of myofibrils and myosin by lactoperoxidase and chloramine-T iodination could be prevented by the attachment of cysteamine to the sulphydryl groups prior to the iodination reaction and subsequent regeneration with thioglycolate or dithiothreitol.	Thioglycolates	249-262	myosin heavy chain 14	Homo sapiens	53-59
6435890-4	1984	Immunoprecipitation with M1/70 demonstrated that Mac 1, the antigen recognized by M1/70, was present on NK and thioglycollate-elicited macrophages.	Thioglycolates	111-125	cholinergic receptor, muscarinic 1, CNS	Mus musculus	25-30
6435890-4	1984	Immunoprecipitation with M1/70 demonstrated that Mac 1, the antigen recognized by M1/70, was present on NK and thioglycollate-elicited macrophages.	Thioglycolates	111-125	integrin alpha M	Mus musculus	49-54
6435890-4	1984	Immunoprecipitation with M1/70 demonstrated that Mac 1, the antigen recognized by M1/70, was present on NK and thioglycollate-elicited macrophages.	Thioglycolates	111-125	cholinergic receptor, muscarinic 1, CNS	Mus musculus	82-87
6207238-2	1984	The Gm-2.2 antigen is found only on bone marrow neutrophils or calcium caseinate-induced neutrophils and is absent from all lymphoid cells examined as well as adherent thioglycollate-induced peritoneal exudate cells and the nonhemopoietic tissues, kidney, liver, heart, brain, and red blood cells.	Thioglycolates	168-182	zinc finger protein 469	Mus musculus	4-10
6437028-4	1984	The inflammatory response to a phlogistic agent, thioglycolate, was also found to be normal in GVH mice, as measured by the accumulation of inflammatory macrophages in the peritoneal cavity.	Thioglycolates	49-62	graft versus host regulation	Mus musculus	95-98
6237161-0	1984	Phospholipase A2 activity of Fc gamma 2b receptors of thioglycollate-elicited murine peritoneal macrophages.	Thioglycolates	54-68	phospholipase A2, group IB, pancreas	Mus musculus	0-16
6237643-1	1984	Intact, thioglycollate-stimulated murine macrophages cultured on an insoluble [3H]-elastin substratum progressively hydrolysed the elastin.	Thioglycolates	8-22	elastin	Mus musculus	83-90
6237643-1	1984	Intact, thioglycollate-stimulated murine macrophages cultured on an insoluble [3H]-elastin substratum progressively hydrolysed the elastin.	Thioglycolates	8-22	elastin	Mus musculus	131-138
6331898-4	1984	Epa-1 expression by PE M phi also could be induced in vivo by M phi-activating agents such as concanavalin A or Bacillus Calmette-Guerin (BCG), but not by the sterile inflammatory agents peptone broth or thioglycolate, suggesting a correlation between Epa-1 phenotype and M phi activation.	Thioglycolates	204-217	epidermal antigen 1	Mus musculus	0-5
6087124-1	1984	Met-enkephalin /Met-enk/ was found to stimulate IgG2a-mediated antibody dependent cytotoxicity /ADCC/ of thioglycollate elicited rat peritoneal macrophages /PM/ through naloxone-sensitive opiate receptors in concentrations ranging from 10(-9) - 14(-7) M. Phagocytosis of IgG2a coated 51Cr-sheep red blood cell /SRBC/ was suppressed by M-enk in the same concentration range.	Thioglycolates	105-119	gamma-2a immunoglobulin heavy chain	Rattus norvegicus	48-53
6087124-1	1984	Met-enkephalin /Met-enk/ was found to stimulate IgG2a-mediated antibody dependent cytotoxicity /ADCC/ of thioglycollate elicited rat peritoneal macrophages /PM/ through naloxone-sensitive opiate receptors in concentrations ranging from 10(-9) - 14(-7) M. Phagocytosis of IgG2a coated 51Cr-sheep red blood cell /SRBC/ was suppressed by M-enk in the same concentration range.	Thioglycolates	105-119	gamma-2a immunoglobulin heavy chain	Rattus norvegicus	271-276
6358037-1	1983	Thioglycolate-induced mouse peritoneal macrophages were activated in vitro by the lymphokine designated macrophage-activating factor (MAF) produced by a murine T cell hybridoma to lyse herpes simplex virus type 2 (HSV-2)-infected murine target cells.	Thioglycolates	0-13	avian musculoaponeurotic fibrosarcoma oncogene homolog	Mus musculus	104-132
6358037-1	1983	Thioglycolate-induced mouse peritoneal macrophages were activated in vitro by the lymphokine designated macrophage-activating factor (MAF) produced by a murine T cell hybridoma to lyse herpes simplex virus type 2 (HSV-2)-infected murine target cells.	Thioglycolates	0-13	avian musculoaponeurotic fibrosarcoma oncogene homolog	Mus musculus	134-137
6619735-3	1983	ApoE represented approximately 1% of the newly synthesized protein and approximately 10% of secreted protein of resident and thioglycollate-elicited macrophages.	Thioglycolates	125-139	apolipoprotein E	Mus musculus	0-4
6619735-4	1983	ApoE from thioglycollate-elicited macrophages was indistinguishable from ApoE in mouse plasma lipoproteins, as determined by immunoreactivity, peptide mapping, and molecular weight.	Thioglycolates	10-24	apolipoprotein E	Mus musculus	0-4
6484310-2	1984	As based on polyacrylamide disc electrophoresis, inactivation of the testicular isozyme, LDH-X, was almost complete with penicillamine and its disulfide, somewhat less with GSH and GSSG, least with thioglycolate and its disulfide and inconsistent with cysteine, 2-mercaptoethanol and 2-mercaptoethylamine.	Thioglycolates	198-211	lactate dehydrogenase C	Homo sapiens	89-94
6319531-6	1984	Macrophage C3 was deposited rapidly, within 10 min, on the zymosan particles and mediated binding, ingestion, and stimulation of superoxide release in BCG-activated and thioglycollate-elicited peritoneal M phi via CR3.	Thioglycolates	169-183	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	214-217
6580500-7	1983	LPS-treated thioglycollate-elicited macrophages induced a higher specific 125I release from tumor cells than the release from untreated macrophages.	Thioglycolates	12-26	toll-like receptor 4	Mus musculus	0-3
6343550-2	1983	We have used this method to study the mechanism of Fc receptor (FcR) disappearance that occurs when resident and thioglycollate-elicited mouse macrophages are cultured on immune complex-coated surfaces.	Thioglycolates	113-127	Fc receptor	Mus musculus	51-62
6225231-4	1983	Blocking the Fc-receptor on thioglycollate-induced macrophages eliminates their ability to reduce the neonatal suppressor cell activity.	Thioglycolates	28-42	Fc receptor	Mus musculus	13-24
6343550-2	1983	We have used this method to study the mechanism of Fc receptor (FcR) disappearance that occurs when resident and thioglycollate-elicited mouse macrophages are cultured on immune complex-coated surfaces.	Thioglycolates	113-127	Fc receptor, IgG, low affinity IIb	Mus musculus	64-67
6840848-1	1983	Immune sensitization of spleen cells was required to generate lymphokines (LK) that activated thioglycolate-elicited peritoneal macrophages (thio MACs) to respond via both oxygen-dependent and oxygen-independent systems.	Thioglycolates	94-107	myristoylated alanine rich protein kinase C substrate	Mus musculus	146-150
6600258-4	1983	The endogenous SAP levels of all strains increased to 180 to 230 micrograms/ml 24 h after an inflammatory stimulus of either thioglycollate (TG) or lipopolysaccharide (LPS).	Thioglycolates	125-139	amyloid P component, serum	Mus musculus	15-18
6600258-4	1983	The endogenous SAP levels of all strains increased to 180 to 230 micrograms/ml 24 h after an inflammatory stimulus of either thioglycollate (TG) or lipopolysaccharide (LPS).	Thioglycolates	141-143	amyloid P component, serum	Mus musculus	15-18
6686788-5	1983	Activation of the thioglycollate-elicited macrophages with macrophage activation factor (MAF) induced threefold higher levels of plasminogen activator production but MAF treatment had no effect on the level of activity produced by macrophagelike cell lines.	Thioglycolates	18-32	MAF bZIP transcription factor	Homo sapiens	89-92
6686788-5	1983	Activation of the thioglycollate-elicited macrophages with macrophage activation factor (MAF) induced threefold higher levels of plasminogen activator production but MAF treatment had no effect on the level of activity produced by macrophagelike cell lines.	Thioglycolates	18-32	MAF bZIP transcription factor	Homo sapiens	166-169
6686788-6	1983	Indeed, the macrophagelike cell lines produced plasminogen activator at levels seen with MAF-activated thioglycollate-elicited macrophages.	Thioglycolates	103-117	MAF bZIP transcription factor	Homo sapiens	89-92
6572895-1	1983	A calmodulin-binding protein is present in extracts of the macrophage-like mouse cell line J774 and in extracts of thioglycollate-stimulated mouse peritoneal macrophages; it is deficient in variants of J774 resistant to trifluoperazine and in resident peritoneal macrophages.	Thioglycolates	115-129	calmodulin 2	Mus musculus	2-12
6572960-3	1983	Thioglycollate-elicited macrophages became Ia-A+ when activated by LKs, but they remained Ia-A- when activated by LPS or IFN-beta.	Thioglycolates	0-14	protein tyrosine phosphatase, receptor type, N	Mus musculus	43-47
6572960-3	1983	Thioglycollate-elicited macrophages became Ia-A+ when activated by LKs, but they remained Ia-A- when activated by LPS or IFN-beta.	Thioglycolates	0-14	protein tyrosine phosphatase, receptor type, N	Mus musculus	90-94
6572960-3	1983	Thioglycollate-elicited macrophages became Ia-A+ when activated by LKs, but they remained Ia-A- when activated by LPS or IFN-beta.	Thioglycolates	0-14	interferon beta 1, fibroblast	Mus musculus	121-129
6813341-2	1982	During in vitro cultivation there is an enhancement in the level of the enzyme in the three populations, and a significant proportion of both thioglycollate-elicited and Corynebacterium parvum-activated macrophages acquire beta-galactosidase activity.	Thioglycolates	142-156	galactosidase, beta 1	Mus musculus	223-241
6806378-5	1982	SAP levels increased five-fold by 24 hr after challenge with lipopolysaccharide (LPS) or thioglycollate.	Thioglycolates	89-103	amyloid P component, serum	Mus musculus	0-3
7045223-4	1982	In contrast, concomitant administration of 2 X 10(7) thioglycollate-stimulated peritoneal exudate adherent cells plus 10(8) alloimmune syngeneic spleen cells produced acute allograft rejection in 50% of B recipients within 10 to 12 days, while in every instance grafts underwent acute rejection (MST +/- SD = 10.0 +/- 1.4 days) in B recipients treated with interleukin 2 (IL 2) rich conditioned supernatant plus sensitized cells.	Thioglycolates	53-67	mercaptopyruvate sulfurtransferase	Homo sapiens	296-299
7045223-4	1982	In contrast, concomitant administration of 2 X 10(7) thioglycollate-stimulated peritoneal exudate adherent cells plus 10(8) alloimmune syngeneic spleen cells produced acute allograft rejection in 50% of B recipients within 10 to 12 days, while in every instance grafts underwent acute rejection (MST +/- SD = 10.0 +/- 1.4 days) in B recipients treated with interleukin 2 (IL 2) rich conditioned supernatant plus sensitized cells.	Thioglycolates	53-67	interleukin 2	Homo sapiens	357-370
7045223-4	1982	In contrast, concomitant administration of 2 X 10(7) thioglycollate-stimulated peritoneal exudate adherent cells plus 10(8) alloimmune syngeneic spleen cells produced acute allograft rejection in 50% of B recipients within 10 to 12 days, while in every instance grafts underwent acute rejection (MST +/- SD = 10.0 +/- 1.4 days) in B recipients treated with interleukin 2 (IL 2) rich conditioned supernatant plus sensitized cells.	Thioglycolates	53-67	interleukin 2	Homo sapiens	372-376
6820888-8	1982	injection of thioglycolate medium were treated in vitro with OK-432 induced IFN gamma, 20 U/ml was shown to activate the cytotoxic effect of M phi on Meth-A cells.	Thioglycolates	13-26	interferon gamma	Mus musculus	76-85
6186124-1	1982	Specific binding of neurotensin (NT) to mouse peritoneal thioglycollate-elicited macrophages and macrophages differentiated in vitro from bone marrow cells was demonstrated and characterized.	Thioglycolates	57-71	neurotensin	Mus musculus	20-31
6279673-3	1982	Binding and uptake of 125I-mannose-BSA and 125I-beta-glucuronidase, respectively, into thioglycollate-induced peritoneal macrophages is saturable (Kd 4 degrees C = 5.4 X 10(-9) M; Kuptake 37 degrees C = 7 X 10(-7) M) and sugar specific.	Thioglycolates	87-101	glucuronidase, beta	Rattus norvegicus	48-66
6173426-2	1982	Co-precipitation experiments show that antigenic determinants recognized by these two antibodies reside on the same molecular species, termed Mac-2, Mac-2, an antigen of 32,000 Mr, is synthesized by and expressed on the surface of thioglycollate-elicited macrophages as shown by [35S]-methionine and 125I labeling.	Thioglycolates	231-245	lectin, galactose binding, soluble 3	Mus musculus	142-147
6173426-2	1982	Co-precipitation experiments show that antigenic determinants recognized by these two antibodies reside on the same molecular species, termed Mac-2, Mac-2, an antigen of 32,000 Mr, is synthesized by and expressed on the surface of thioglycollate-elicited macrophages as shown by [35S]-methionine and 125I labeling.	Thioglycolates	231-245	lectin, galactose binding, soluble 3	Mus musculus	149-154
6173426-3	1982	Saturation binding experiments show that thioglycollate-elicited macrophages express 1.7 X 10(5) Mac-2 sites/cell.	Thioglycolates	41-55	lectin, galactose binding, soluble 3	Mus musculus	97-102
6173426-9	1982	In contrast, thioglycollate-elicited macrophages are greater than 96% strongly positive for Mac-2.	Thioglycolates	13-27	lectin, galactose binding, soluble 3	Mus musculus	92-97
6173426-11	1982	SDS-PAGE of [35S]-methionine-labeled Mac-2 shows that thioglycollate-elicited macrophages synthesize 10- to 30-fold more Mac-2 than other peritoneal macrophage subpopulations, whereas all types of peritoneal macrophages synthesize and express on their surfaces similar amounts of the Mac-1 antigen.	Thioglycolates	54-68	lectin, galactose binding, soluble 3	Mus musculus	37-42
6173426-11	1982	SDS-PAGE of [35S]-methionine-labeled Mac-2 shows that thioglycollate-elicited macrophages synthesize 10- to 30-fold more Mac-2 than other peritoneal macrophage subpopulations, whereas all types of peritoneal macrophages synthesize and express on their surfaces similar amounts of the Mac-1 antigen.	Thioglycolates	54-68	lectin, galactose binding, soluble 3	Mus musculus	121-126
6173426-11	1982	SDS-PAGE of [35S]-methionine-labeled Mac-2 shows that thioglycollate-elicited macrophages synthesize 10- to 30-fold more Mac-2 than other peritoneal macrophage subpopulations, whereas all types of peritoneal macrophages synthesize and express on their surfaces similar amounts of the Mac-1 antigen.	Thioglycolates	54-68	integrin alpha M	Mus musculus	284-289
6186124-5	1982	Three partial sequences of NT, NT (8-13), NT (6-13) and NT (1-10), were also effective in augmenting the phagocytic response of thioglycollate elicited macrophages, but the maximal effect was attained at about 10(-7) M and stayed at that level up to a concentration of 10(-5) M. The activity of the three NT partial sequences was comparable to that of substance P and tuftsin.	Thioglycolates	128-142	tachykinin 1	Mus musculus	352-363
6273401-1	1981	Cholesterol esterase with optimal activity at pH 6.8 was found in the 40,000 X g supernatant fraction prepared from rabbit alveolar macrophages, thioglycolate-elicited mouse peritoneal macrophages, and the J774 macrophage cell line.	Thioglycolates	145-158	carboxyl ester lipase	Mus musculus	0-20
6267131-2	1981	A 48-hr incubation of murine thioglycollate-elicited macrophages with LPS (0.1 micrograms/ml) resulted in an enhanced ability of these cells to produce oxygen radicals when challenged with phorbol myristate acetate (PMA).	Thioglycolates	29-43	toll-like receptor 4	Mus musculus	70-73
7298642-14	1981	The formation of a quaternary complex consisting of thioglycolate-Fe2+-transferrin-CO3(2-) is suggested.	Thioglycolates	52-65	transferrin	Homo sapiens	71-82
7229378-3	1981	In the presence of small volumes of hyperimmune serum or IgG2a antibody, thioglycollate-elicited B6 mouse peritoneal cells (PEC) inhibit the growth of AD755 Cl.10 target cells and other cells provided that they express FLV-related antigens.	Thioglycolates	73-87	immunoglobulin heavy variable V1-9	Mus musculus	57-62
7308288-1	1981	A hybridoma clone which secretes a macrophage (M phi)-specific monoclonal antibody, F4/80, was produced by fusing spleen cells from a rat hyperimmunized with cultured thioglycollate-induced mouse peritoneal M phi with a mouse myeloma, NS1.	Thioglycolates	167-181	adhesion G protein-coupled receptor E1	Mus musculus	84-89
7308288-1	1981	A hybridoma clone which secretes a macrophage (M phi)-specific monoclonal antibody, F4/80, was produced by fusing spleen cells from a rat hyperimmunized with cultured thioglycollate-induced mouse peritoneal M phi with a mouse myeloma, NS1.	Thioglycolates	167-181	influenza virus NS1A binding protein	Mus musculus	235-238
6251133-3	1980	Thioglycollate-elicited macrophages showed a unique ectoenzyme phenotype, with increased leucine aminopeptidase and alkaline phosphodiesterase I activity and markedly reduced 5"-nucleotidase activity as compared with resident macrophages.	Thioglycolates	0-14	5' nucleotidase, ecto	Mus musculus	175-190
907799-2	1977	Following a single intraperitoneal thioglycollate injection there was a marked increase in TCII which was shown to be produced by the adherent cells of the PEC i.e. the macrophages.	Thioglycolates	35-49	transcobalamin 2	Mus musculus	91-95
6901615-1	1980	Cultured thioglycollate-elicited mouse peritoneal macrophages secrete an enzyme which hydrolyzes [3H]elastin prepared by NaB3H4 reduction of bovine ligamentum nuchae elastin.	Thioglycolates	9-23	elastin	Mus musculus	101-108
6901615-1	1980	Cultured thioglycollate-elicited mouse peritoneal macrophages secrete an enzyme which hydrolyzes [3H]elastin prepared by NaB3H4 reduction of bovine ligamentum nuchae elastin.	Thioglycolates	9-23	elastin	Bos taurus	166-173
6901615-3	1980	10(6) thioglycollate-elicited cells secrete sufficient enzyme to solubilize 200--350 micrograms [3H]elastin in 18h.	Thioglycolates	6-20	elastin	Mus musculus	100-107
114527-2	1979	We have purified beta-galactosidase and beta-glucuronidase from macrophages of thioglycollate-treated mice using concanavalin A chromatography and immunoprecipitation.	Thioglycolates	79-93	galactosidase, beta 1	Mus musculus	17-35
114527-2	1979	We have purified beta-galactosidase and beta-glucuronidase from macrophages of thioglycollate-treated mice using concanavalin A chromatography and immunoprecipitation.	Thioglycolates	79-93	glucuronidase, beta	Mus musculus	40-58
313429-2	1979	Bone marrow-derived macrophages (BMDM) obtained after 6-8-d cultivation in a liquid medium containing L-cell-conditioned medium (LCM), a source of colony stimulating factor (CSF), showed a high level of fibrinolytic activity comparable to that of thioglycollate medium-induced peritoneal macrophages (TPM) and at least 20-fold higher than that of resident peritoneal macrophages (RPM).	Thioglycolates	247-261	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	174-177
107545-5	1978	Homogenates of PCs from mice injected with the immunomodulators C. parvum, levamisole HCl, pyran copolymer, or thioglycollate yielded less PGI2.	Thioglycolates	111-125	prostaglandin I receptor (IP)	Mus musculus	139-143
670887-6	1978	The activities of 5"-nucleotidase and leucine aminopeptidase in the cultured granuloma cells showed that they resembled macrophages from thioglycollate-stimulated mice but not unstimulated macrophages in these respects.	Thioglycolates	137-151	5' nucleotidase, ecto	Mus musculus	18-33
650153-1	1978	Thioglycolate-stimulated mouse peritoneal macrophages cultured in the presence of macrophage growth factor (MGF) will continue to proliferate when they are removed from culture dishes with the local anesthetic lidocaine and subcultured.	Thioglycolates	0-13	kit ligand	Mus musculus	108-111
917013-0	1977	Increase of phagocytic activity and new appearance of a C4b (guinea pig) recognizing capability in peritoneal macrophages from Corynebacterium parvum and thioglycollate-stimulated mice.	Thioglycolates	154-168	complement component 4B (Chido blood group)	Mus musculus	56-59
405222-1	1977	After in vivo treatment of mice with thioglycollate medium, the amount of native factor B which could be detected in vitro in culture supernatants of peritoneal macrophages was much lower than that found in supernatants of macrophages taken from untreated mice.	Thioglycolates	37-51	complement factor B	Mus musculus	81-89
405222-2	1977	However, when the macrophages from thioglycollate medium-treated mice were cultured on a plastic surface covered with glutardialdehyde-linked bovine serum albumin, the culture supernatants contained larger quantities of native factor B than culture supernatants of macrophages from untreated mice under the same conditions.	Thioglycolates	35-49	complement factor B	Mus musculus	227-235
405222-3	1977	Thus, the effect of in vivo thioglycollate medium treatment on the in vitro secretion of factor B by peritoneal macrophages could be modulated by the culture conditions.	Thioglycolates	28-42	complement factor B	Mus musculus	89-97
167096-2	1975	Thioglycolate-stimulated mouse peritoneal macrophages secrete a Proteinase which degrades insoluble elastin.	Thioglycolates	0-13	elastin	Mus musculus	100-107
181097-1	1976	Serum haptoglobin is elevated by treatment of mice with thioglycollate, B.C.G.	Thioglycolates	56-70	haptoglobin	Mus musculus	6-17
181097-4	1976	The numbers and characteristics of peritoneal exudate cells present following intraperitoneal thioglycollate inoculation suggest a relationship between phagocytic activity and serum haptoglobin levels and support the idea that serum haptoglobin levels may be controlled by mediators released during the process of phagocytosis.	Thioglycolates	94-108	haptoglobin	Mus musculus	182-193
181097-4	1976	The numbers and characteristics of peritoneal exudate cells present following intraperitoneal thioglycollate inoculation suggest a relationship between phagocytic activity and serum haptoglobin levels and support the idea that serum haptoglobin levels may be controlled by mediators released during the process of phagocytosis.	Thioglycolates	94-108	haptoglobin	Mus musculus	233-244
1194857-4	1975	The number of binding sites per cell for IgG2a was 4 X 10(5) for thioglycollate-stimulated cells and 1 X 10(5) for normal and P388D1 cells.	Thioglycolates	65-79	immunoglobulin heavy variable V1-9	Mus musculus	41-46
5348287-1	1969	Incubation with thioglycollate destroyed biologic activity of oxytocin, but left immunologic activity intact.	Thioglycolates	16-30	oxytocin/neurophysin I prepropeptide	Homo sapiens	62-70
4427092-1	1974	The injection of thioglycollate medium into the peritoneal cavity of the mouse induces high levels of macrophage fibrinolytic activity due to the production and secretion of a plasminogen activator, a trypsinlike serine protease, which is absent in unstimulated macrophages.	Thioglycolates	17-31	complement component 1, s subcomponent 1	Mus musculus	213-228
4825244-1	1974	Pure cultures of three types of mononuclear phagocytes-mouse peritoneal macrophages, unstimulated or after thioglycollate stimulation, and human monocytes-synthesize and secrete large amounts of lysozyme in vitro.	Thioglycolates	107-121	lysozyme	Homo sapiens	195-203
4825244-4	1974	Lysozyme is the major (14)C-labeled protein secreted into the medium by both unstimulated and thioglycollate-stimulated macrophages and the 0.75-1 microg produced per 1 x 10(6) cells/day represents 0.5-2.5% of the total cell protein.	Thioglycolates	94-108	lysozyme	Homo sapiens	0-8
5365339-2	1969	This suggested that sulphydryl radicals, which are the active groups in thioglycollate and related compounds, may play a part in the uptake of iron by immature red cells from iron transferrin.	Thioglycolates	72-86	transferrin	Homo sapiens	180-191
6018744-3	1967	Thioglycolate inactivation was used to confirm AVP activity.	Thioglycolates	0-13	arginine vasopressin	Homo sapiens	47-50
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	low density lipoprotein receptor	Mus musculus	85-89
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	low density lipoprotein receptor	Mus musculus	133-137
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	interferon beta 1, fibroblast	Mus musculus	244-259
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	tumor necrosis factor	Mus musculus	329-333
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	chemokine (C-X-C motif) ligand 1	Mus musculus	335-340
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	chemokine (C-C motif) ligand 2	Mus musculus	342-346
33882688-7	2021	Sorted thioglycollate-elicited peritoneal macrophages freshly isolated from APOA1Tg; Ldlr-/- mice, which have higher HDL levels than Ldlr-/- controls, showed reduced expression of interferon-inducible genes in response to lipopolysaccharide or interferon-beta, but exacerbated proinflammatory responses to lipopolysaccharide for Tnfa, Cxcl1, Ccl2, and Il1b, phenocopying cells stimulated with HDL in vitro.	Thioglycolates	7-21	interleukin 1 beta	Mus musculus	352-356
32655973-9	2020	In an in vitro assay using thioglycollate-induced peritoneal neutrophils, the ability of bacterial phagocytosis and killing was impaired in CRAMP-/- neutrophils compared to the WT cells.	Thioglycolates	27-41	cathelicidin antimicrobial peptide	Mus musculus	140-145
33459130-1	2021	Thioglycolate-elicited macrophages exhibit abundant conjugation of LC3 with PE (LC3-II).	Thioglycolates	0-13	microtubule-associated protein 1 light chain 3 alpha	Mus musculus	67-70
33322474-7	2020	We used a thioglycolate-induced peritonitis model to demonstrate a role for CCR2/MCP-1 in trafficking of CCR2+ cells to an inflammatory site, and showed the ability of a CCR2 antagonist to inhibit such trafficking.	Thioglycolates	10-23	chemokine (C-C motif) receptor 2	Mus musculus	76-80
33322474-7	2020	We used a thioglycolate-induced peritonitis model to demonstrate a role for CCR2/MCP-1 in trafficking of CCR2+ cells to an inflammatory site, and showed the ability of a CCR2 antagonist to inhibit such trafficking.	Thioglycolates	10-23	chemokine (C-C motif) receptor 2	Mus musculus	105-109
33322474-7	2020	We used a thioglycolate-induced peritonitis model to demonstrate a role for CCR2/MCP-1 in trafficking of CCR2+ cells to an inflammatory site, and showed the ability of a CCR2 antagonist to inhibit such trafficking.	Thioglycolates	10-23	chemokine (C-C motif) receptor 2	Mus musculus	105-109
33028307-13	2020	CONCLUSION: Our findings manifested that ACE inhibited LPS or TG-induced inflammation by blocking the NF-kappaB signaling pathway in macrophages.	Thioglycolates	62-64	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	41-44
33565143-11	2021	Finally, when E-selectin was blocked in vivo in mice, thioglycollate-elicited macrophages showed reduced CD86 expression validating our in vitro studies.	Thioglycolates	54-68	selectin, endothelial cell	Mus musculus	14-24
33565143-11	2021	Finally, when E-selectin was blocked in vivo in mice, thioglycollate-elicited macrophages showed reduced CD86 expression validating our in vitro studies.	Thioglycolates	54-68	CD86 antigen	Mus musculus	105-109
32803667-9	2020	FACS analyses of thioglycollate-elicited peritoneal cells revealed that diverse leukocyte subsets were reduced in EC-BMP4-/- mice.	Thioglycolates	17-31	bone morphogenetic protein 4	Mus musculus	117-121
31980446-4	2020	Thioglycollate-elicited myeloid cells from the peritoneum were cultured and treated with IFNalpha to induce the T cell suppressor phenotype, expression of MIR130b and SLFN4.	Thioglycolates	0-14	interferon alpha 1	Homo sapiens	89-97
31980446-4	2020	Thioglycollate-elicited myeloid cells from the peritoneum were cultured and treated with IFNalpha to induce the T cell suppressor phenotype, expression of MIR130b and SLFN4.	Thioglycolates	0-14	microRNA 130b	Mus musculus	155-162
31980446-4	2020	Thioglycollate-elicited myeloid cells from the peritoneum were cultured and treated with IFNalpha to induce the T cell suppressor phenotype, expression of MIR130b and SLFN4.	Thioglycolates	0-14	schlafen 4	Mus musculus	167-172
31680771-5	2019	Pretreatment with RhoA and RhoB decreased inducible nitric oxide synthase and cyclooxygenase-2 expressions in RAW 264.7 cells and in thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	133-147	ras homolog family member A	Mus musculus	18-22
32019585-12	2020	Thioglycolate-activated neutrophils were isolated, treated with recombinant CXCL1, and measured for ROS production.	Thioglycolates	0-13	chemokine (C-X-C motif) ligand 1	Mus musculus	76-81
31520477-6	2019	GM-CSF also enhanced Siglec-F expression in thioglycollate-induced peritoneal macrophages.	Thioglycolates	44-58	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-6
31520477-6	2019	GM-CSF also enhanced Siglec-F expression in thioglycollate-induced peritoneal macrophages.	Thioglycolates	44-58	sialic acid binding Ig-like lectin F	Mus musculus	21-29
31680771-5	2019	Pretreatment with RhoA and RhoB decreased inducible nitric oxide synthase and cyclooxygenase-2 expressions in RAW 264.7 cells and in thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	133-147	ras homolog family member B	Mus musculus	27-31
31649967-2	2019	We here provide a protocol to quantify the LPS dependent internalization of TLR4 using thioglycollate-elicited peritoneal macrophages by flow cytometry.	Thioglycolates	87-101	toll-like receptor 4	Mus musculus	43-46
31649967-2	2019	We here provide a protocol to quantify the LPS dependent internalization of TLR4 using thioglycollate-elicited peritoneal macrophages by flow cytometry.	Thioglycolates	87-101	toll-like receptor 4	Mus musculus	76-80
29601102-7	2019	Similar findings were observed in thioglycolate-elicited peritoneal macrophages, in which RvD2 remarkably reduced ASC oligomerization, inflammasome assembly, and caspase-1 activity.	Thioglycolates	34-47	PYD and CARD domain containing	Homo sapiens	114-117
31216192-4	2019	In this study, using a model of partially activated, recruited thioglycollate-elicited peritoneal macrophages, a transient, transcription profile of key functional genes in macrophages exposed to EMAP II was characterized.	Thioglycolates	63-77	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	Mus musculus	196-203
29601102-7	2019	Similar findings were observed in thioglycolate-elicited peritoneal macrophages, in which RvD2 remarkably reduced ASC oligomerization, inflammasome assembly, and caspase-1 activity.	Thioglycolates	34-47	caspase 1	Homo sapiens	162-171
29850779-1	2018	Aims: We previously found that miR-10b inhibits cholesterol efflux from thioglycollate-elicited mouse peritoneal macrophages through repressing ATP binding cassette transporter (ABCA1).	Thioglycolates	72-86	microRNA 10b	Mus musculus	31-38
29850779-1	2018	Aims: We previously found that miR-10b inhibits cholesterol efflux from thioglycollate-elicited mouse peritoneal macrophages through repressing ATP binding cassette transporter (ABCA1).	Thioglycolates	72-86	ATP-binding cassette, sub-family A (ABC1), member 13	Mus musculus	144-176
29850779-1	2018	Aims: We previously found that miR-10b inhibits cholesterol efflux from thioglycollate-elicited mouse peritoneal macrophages through repressing ATP binding cassette transporter (ABCA1).	Thioglycolates	72-86	ATP-binding cassette, sub-family A (ABC1), member 1	Mus musculus	178-183
30053916-5	2018	RESULTS: Thioglycolate-elicited peritoneal macrophages from BALB/c mice were stimulated by lipopolysaccharide (LPS) plus interferon-gamma (IFN-gamma) in the presence or absence of recombinant HTB.	Thioglycolates	9-22	interferon gamma	Mus musculus	121-137
30174703-8	2018	AME increased the number of SRA(+)CD11b(+) cells in response to thioglycollate.	Thioglycolates	64-78	integrin subunit alpha M	Homo sapiens	34-39
30443252-10	2018	During thioglycolate-induced peritonitis, adoptively transferred macrophages with Egr2 knockdown failed to become activated as determined by upregulation of MHC class II and CD86.	Thioglycolates	7-20	early growth response 2	Mus musculus	82-86
30053407-2	2018	Gpr39 expression increased in thioglycollate-induced peritoneal macrophages.	Thioglycolates	30-44	G protein-coupled receptor 39	Mus musculus	0-5
30053407-3	2018	TC-G 1008, a G protein-coupled receptor 39 agonist, enhanced interleukin (IL)-10 production from thioglycollate-induced peritoneal macrophages stimulated with lipopolysaccharide (LPS) in vitro.	Thioglycolates	97-111	G protein-coupled receptor 39	Mus musculus	13-42
30053407-3	2018	TC-G 1008, a G protein-coupled receptor 39 agonist, enhanced interleukin (IL)-10 production from thioglycollate-induced peritoneal macrophages stimulated with lipopolysaccharide (LPS) in vitro.	Thioglycolates	97-111	interleukin 10	Mus musculus	61-80
30053407-5	2018	The ablation of G protein-coupled receptor 39 significantly reduced IL-10 production by TC-G 1008 in thioglycollate-induced peritoneal macrophages stimulated with LPS and in the LPS-induced murine model of sepsis.	Thioglycolates	101-115	G protein-coupled receptor 39	Mus musculus	16-45
30053407-5	2018	The ablation of G protein-coupled receptor 39 significantly reduced IL-10 production by TC-G 1008 in thioglycollate-induced peritoneal macrophages stimulated with LPS and in the LPS-induced murine model of sepsis.	Thioglycolates	101-115	interleukin 10	Mus musculus	68-73
29929985-5	2018	We detected significantly more neutrophils in the airways of Rgs5-/- mice than WT counterparts following acute respiratory virus infection and in the peritoneum in response to injection of thioglycollate, a biochemical proinflammatory stimulus.	Thioglycolates	189-203	regulator of G-protein signaling 5	Mus musculus	61-65
30053916-5	2018	RESULTS: Thioglycolate-elicited peritoneal macrophages from BALB/c mice were stimulated by lipopolysaccharide (LPS) plus interferon-gamma (IFN-gamma) in the presence or absence of recombinant HTB.	Thioglycolates	9-22	interferon gamma	Mus musculus	139-148
28755278-9	2017	Endothelial cell-specific deletion of BMP4 in mice markedly diminished leukocyte diapedesis following thioglycollate administration suggesting that endothelial BMP4 is required for leukocyte recruitment.	Thioglycolates	102-116	bone morphogenetic protein 4	Mus musculus	38-42
28892097-7	2017	RNA-seq analysis revealed that SGA360 attenuated the expression of numerous inflammatory genes and genes known to be directly regulated by AHR in thioglycolate-elicited primary peritoneal macrophages treated with LPS.	Thioglycolates	146-159	aryl-hydrocarbon receptor	Mus musculus	139-142
28754304-6	2017	The specificity of 747 on CCR2 was demonstrated via calcium flux, the binding domain of CCR2 was identified in an extracellular loop by chimera binding assay, and in vivo antagonistic activity of 747 was confirmed through a thioglycollate-induced peritonitis model.	Thioglycolates	224-238	C-C motif chemokine receptor 2	Homo sapiens	88-92
29209334-6	2017	Using the zymosan- and thioglycollate-induced murine models of acute inflammation, we report that mice deficient in the Ccrl2 gene display exaggerated local and systemic inflammatory responses, characterised by increased myeloid cell recruitment.	Thioglycolates	23-37	chemokine (C-C motif) receptor-like 2	Mus musculus	120-125
28768810-8	2017	Resident peritoneal macrophages, Kupffer cells, and CD169+ skin macrophages required Tim4 for TAM-stimulated efferocytosis, whereas efferocytosis by thioglycollate-elicited peritoneal macrophages or primary cultured microglia was TAM dependent, but not Tim4 dependent.	Thioglycolates	149-163	T cell immunoglobulin and mucin domain containing 4	Mus musculus	253-257
28473436-6	2017	Thioglycollate-elicited peritoneal macrophages from Aath4aDBA/DBA mice express less than 50% of Mertk mRNA and cell-surface MERTK protein compared with those from the control mice.	Thioglycolates	0-14	MER proto-oncogene tyrosine kinase	Mus musculus	96-101
28473436-6	2017	Thioglycollate-elicited peritoneal macrophages from Aath4aDBA/DBA mice express less than 50% of Mertk mRNA and cell-surface MERTK protein compared with those from the control mice.	Thioglycolates	0-14	MER proto-oncogene tyrosine kinase	Mus musculus	124-129
28353029-3	2017	Thioglycollate-elicited peritoneal macrophages derived from the young (2 months old) and the naturally senescent intact middle-aged (16 months old) male and female rats were tested for cytokine secretion and antimicrobial activity (NO and H2O2 production and myeloperoxidase activity).	Thioglycolates	0-14	myeloperoxidase	Rattus norvegicus	259-274
28181039-6	2017	The peritoneal lavage fluid collected from IRF3 KO mice 4 h after intraperitoneal injection with P. aeruginosa or 3% thioglycolate contained a significantly increased number of neutrophils.	Thioglycolates	117-130	interferon regulatory factor 3	Mus musculus	43-47
28356348-6	2017	Tpl2-/- neutrophils show impaired recruitment to thioglycollate, which was primarily a result of neutrophil-extrinsic factors in the host.	Thioglycolates	49-63	mitogen-activated protein kinase kinase kinase 8	Mus musculus	0-4
27145012-2	2016	11beta-HSD1 is highly expressed in immune cells elicited to the mouse peritoneum during thioglycollate-induced peritonitis and is down-regulated as the inflammation resolves.	Thioglycolates	88-102	hydroxysteroid 11-beta dehydrogenase 1	Mus musculus	0-11
27648699-5	2017	We found that RAW 264.7 cells (XYZ), mouse peritoneal resident, thioglycollate-elicited macrophages, primed RAW 264.7 (XYZ, LMP), and human monocytes (LMP) expressed different types of proteasome subunits/activities.	Thioglycolates	64-78	PDZ and LIM domain 7	Mus musculus	124-127
27648699-5	2017	We found that RAW 264.7 cells (XYZ), mouse peritoneal resident, thioglycollate-elicited macrophages, primed RAW 264.7 (XYZ, LMP), and human monocytes (LMP) expressed different types of proteasome subunits/activities.	Thioglycolates	64-78	PDZ and LIM domain 7	Mus musculus	151-154
27235884-5	2017	Using thioglycollate-induced peritonitis as a model, we showed that the activated immune system regulates the pineal gland by inhibition of melatonin production at the level of the key enzyme in its biosynthetic pathway, arylalkylamine-N-acetyltransferase (AANAT).	Thioglycolates	6-20	aralkylamine N-acetyltransferase	Gallus gallus	221-255
27235884-5	2017	Using thioglycollate-induced peritonitis as a model, we showed that the activated immune system regulates the pineal gland by inhibition of melatonin production at the level of the key enzyme in its biosynthetic pathway, arylalkylamine-N-acetyltransferase (AANAT).	Thioglycolates	6-20	aralkylamine N-acetyltransferase	Gallus gallus	257-262
27145012-9	2016	Similar to genetic deficiency in 11beta-HSD1, acute inhibition of 11beta-HSD1 activity during thioglycollate-induced peritonitis augmented inflammatory cell recruitment to the peritoneum.	Thioglycolates	94-108	hydroxysteroid 11-beta dehydrogenase 1	Mus musculus	66-77
28017830-5	2017	Coculture of dFb with human monocytes in vitro or injection of dFb into mice with thioglycollate-induced peritonitis favors alternative macrophage activation and reduces inflammation by releasing tumor necrosis factor-inducible gene 6 protein and Cox-2 products.	Thioglycolates	82-96	tumor necrosis factor alpha induced protein 6	Mus musculus	196-242
28017830-5	2017	Coculture of dFb with human monocytes in vitro or injection of dFb into mice with thioglycollate-induced peritonitis favors alternative macrophage activation and reduces inflammation by releasing tumor necrosis factor-inducible gene 6 protein and Cox-2 products.	Thioglycolates	82-96	cytochrome c oxidase II, mitochondrial	Mus musculus	247-252
27864142-6	2017	However, upon thioglycolate challenge, neutrophils from both untreated and G-CSF-treated G6pt-/-mice exhibited decreased ability to migrate to the peritoneal cavity.	Thioglycolates	14-27	colony stimulating factor 3 (granulocyte)	Mus musculus	75-80
27756630-6	2016	In middle-aged DA rats injection of thioglycollate diminished IL-6 production, but increased it in response to LPS stimulation.	Thioglycolates	36-50	interleukin 6	Rattus norvegicus	62-66
27756630-8	2016	Although the thioglycollate injection has increased the proportion of CD86+MHCII+ mature macrophages in young rats, and percentages of activated TLR4+ macrophages in both age groups of AO rats, it has not affected the cytokine production in young rats" macrophages, and the TNF-alpha production in middle-aged rats" macrophages.	Thioglycolates	13-27	CD86 molecule	Rattus norvegicus	70-74
27145012-5	2016	Here we have identified neutrophils (CD11b(+),Ly6G(+),7/4(+) cells) as the thioglycollate-recruited cells that most highly express 11beta-HSD1 and show dynamic regulation of 11beta-HSD1 in these cells during an inflammatory response.	Thioglycolates	75-89	integrin subunit alpha M	Homo sapiens	37-42
27145012-5	2016	Here we have identified neutrophils (CD11b(+),Ly6G(+),7/4(+) cells) as the thioglycollate-recruited cells that most highly express 11beta-HSD1 and show dynamic regulation of 11beta-HSD1 in these cells during an inflammatory response.	Thioglycolates	75-89	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	131-142
27145012-5	2016	Here we have identified neutrophils (CD11b(+),Ly6G(+),7/4(+) cells) as the thioglycollate-recruited cells that most highly express 11beta-HSD1 and show dynamic regulation of 11beta-HSD1 in these cells during an inflammatory response.	Thioglycolates	75-89	hydroxysteroid 11-beta dehydrogenase 1	Homo sapiens	174-185
26791830-0	2016	Mercaptoacetate blocks fatty acid-induced GLP-1 secretion in male rats by directly antagonizing GPR40 fatty acid receptors.	Thioglycolates	0-15	glucagon	Rattus norvegicus	42-47
26984894-0	2016	Deletion of GPR40 fatty acid receptor gene in mice blocks mercaptoacetate-induced feeding.	Thioglycolates	58-73	free fatty acid receptor 1	Mus musculus	12-17
26842698-9	2016	Also PIF prevented leukocyte extravasation (peritonitis thioglycollate-induced model), demonstrating that PIF exerts its effect in part by modulation of monocyte function.	Thioglycolates	56-70	Pif	Mus musculus	5-8
26842698-9	2016	Also PIF prevented leukocyte extravasation (peritonitis thioglycollate-induced model), demonstrating that PIF exerts its effect in part by modulation of monocyte function.	Thioglycolates	56-70	Pif	Mus musculus	106-109
26791830-0	2016	Mercaptoacetate blocks fatty acid-induced GLP-1 secretion in male rats by directly antagonizing GPR40 fatty acid receptors.	Thioglycolates	0-15	free fatty acid receptor 1	Rattus norvegicus	96-101
26321243-7	2015	Mice lacking CD99L2 had a defective inflammatory response in the thioglycollate peritonitis model with a greater than 80% block in neutrophil infiltration and a nearly complete block in monocyte emigration into the peritoneal cavity measured 16h after the inflammatory challenge.	Thioglycolates	65-79	CD99 antigen-like 2	Mus musculus	13-19
26711562-5	2016	Cell surface analysis showed that sleep deprivation reduced F4/80(+)/CD80(low) peritoneal cell population induced by thioglycollate injection.	Thioglycolates	117-131	CD80 antigen	Mus musculus	69-73
26463212-6	2016	The upregulated production of IL-1beta, IL-6 and IL-10 and downregulated that of TGF-beta was observed in response to LPS in resident and thioglycollate-elicited macrophages from rats of both ages.	Thioglycolates	138-152	interleukin 1 beta	Rattus norvegicus	30-38
26463212-6	2016	The upregulated production of IL-1beta, IL-6 and IL-10 and downregulated that of TGF-beta was observed in response to LPS in resident and thioglycollate-elicited macrophages from rats of both ages.	Thioglycolates	138-152	interleukin 6	Rattus norvegicus	40-44
26463212-6	2016	The upregulated production of IL-1beta, IL-6 and IL-10 and downregulated that of TGF-beta was observed in response to LPS in resident and thioglycollate-elicited macrophages from rats of both ages.	Thioglycolates	138-152	interleukin 10	Rattus norvegicus	49-54
26463212-6	2016	The upregulated production of IL-1beta, IL-6 and IL-10 and downregulated that of TGF-beta was observed in response to LPS in resident and thioglycollate-elicited macrophages from rats of both ages.	Thioglycolates	138-152	transforming growth factor, beta 1	Rattus norvegicus	81-89
26463212-7	2016	GM-CSF elevated production of IL-1beta and IL-6 in resident macrophages from aged rats and in thioglycollate-elicited macrophages from young rats.	Thioglycolates	94-108	colony stimulating factor 2	Rattus norvegicus	0-6
26463212-10	2016	Conversely, IL-4 reduced NO/urea ratio in resident and thioglycollate-elicited macrophages from young rats only.	Thioglycolates	55-69	interleukin 4	Rattus norvegicus	12-16
26611322-4	2015	The results indicate that a thioglycollate-induced exudation of leukocytes into the peritoneal cavity was suppressed by the genetic-deletion of PGIS.	Thioglycolates	28-42	prostaglandin I2 (prostacyclin) synthase	Mus musculus	144-148
25964052-4	2015	The present study showed that ApoE/p110delta DKO mice fed with a high cholesterol diet (HCD) demonstrated less peritoneal infiltration of leukocytes and monocytes compared with ApoE KO mice after intraperitoneal injection of thioglycollate, an inducer of acute peritoneal inflammation.	Thioglycolates	225-239	apolipoprotein E	Mus musculus	30-34
26300344-5	2015	Furthermore, thioglycollate-induced migration of macrophages and B cells is enhanced in FHL2-KO mice.	Thioglycolates	13-27	four and a half LIM domains 2	Mus musculus	88-92
25964052-4	2015	The present study showed that ApoE/p110delta DKO mice fed with a high cholesterol diet (HCD) demonstrated less peritoneal infiltration of leukocytes and monocytes compared with ApoE KO mice after intraperitoneal injection of thioglycollate, an inducer of acute peritoneal inflammation.	Thioglycolates	225-239	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Mus musculus	35-44
25767273-8	2015	Peritoneal thioglycollate injection elicited equivalent numbers of monocytes and macrophages in both groups, but a significantly lower number of proinflammatory Ly6C high monocytes were recruited in ApoE/FHL2-/- versus ApoE-/- mice.	Thioglycolates	11-25	four and a half LIM domains 2	Mus musculus	204-208
25926623-6	2015	While G2019S LRRK2 expression did not affect immunological homeostasis, myeloid cells expressing G2019S LRRK2 show enhanced chemotaxis both in vitro in two-chamber assays and in vivo in response to thioglycollate injections in the peritoneum.	Thioglycolates	198-212	leucine-rich repeat kinase 2	Rattus norvegicus	104-109
25964052-0	2015	p110Delta Inhibits Monocyte Infiltration by Thioglycollate-Induced Periotoneal Inflammation but Not HCD-Induced Inflammation and Atherosclerosis in APOE KO Mice.	Thioglycolates	44-58	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Mus musculus	0-9
26026062-4	2015	In contrast, we found that bone marrow-derived and thioglycollate-elicited peritoneal macrophages deficient for Btk and Tec secrete more proinflammatory cytokines than do wild-type cells.	Thioglycolates	51-65	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	112-115
26026062-4	2015	In contrast, we found that bone marrow-derived and thioglycollate-elicited peritoneal macrophages deficient for Btk and Tec secrete more proinflammatory cytokines than do wild-type cells.	Thioglycolates	51-65	tec protein tyrosine kinase	Mus musculus	120-123
25767273-8	2015	Peritoneal thioglycollate injection elicited equivalent numbers of monocytes and macrophages in both groups, but a significantly lower number of proinflammatory Ly6C high monocytes were recruited in ApoE/FHL2-/- versus ApoE-/- mice.	Thioglycolates	11-25	lymphocyte antigen 6 complex, locus C1	Mus musculus	161-165
25767273-8	2015	Peritoneal thioglycollate injection elicited equivalent numbers of monocytes and macrophages in both groups, but a significantly lower number of proinflammatory Ly6C high monocytes were recruited in ApoE/FHL2-/- versus ApoE-/- mice.	Thioglycolates	11-25	apolipoprotein E	Mus musculus	199-203
25767273-8	2015	Peritoneal thioglycollate injection elicited equivalent numbers of monocytes and macrophages in both groups, but a significantly lower number of proinflammatory Ly6C high monocytes were recruited in ApoE/FHL2-/- versus ApoE-/- mice.	Thioglycolates	11-25	apolipoprotein E	Mus musculus	219-223
25538043-2	2015	Thioglycollate-induced neutrophil recruitment into the peritoneum was more severely impaired in P-Rex1(-/-) Vav1(-/-) (P1V1) or P-Rex1(-/-) Vav3(-/-) (P1V3) mice than in P-Rex null or Vav null mice, suggesting cooperation between P-Rex and Vav Rac-GEFs in this process.	Thioglycolates	0-14	vav 1 oncogene	Mus musculus	96-112
25614279-7	2015	As determined by Boyden chamber, thioglycollate-induced peritonitis and air pouch model, migration of SGK1-deficient CD11b(+)F4/80(+) macrophages was significantly diminished in vitro and in vivo.	Thioglycolates	33-47	integrin subunit alpha M	Homo sapiens	117-122
25267883-7	2015	Enhanced CCL24 expression was also observed in GM-CSF-induced BMDMs and zymosan-elicited, thioglycolate-elicited and naive peritoneal macrophages.	Thioglycolates	90-103	chemokine (C-C motif) ligand 24	Mus musculus	9-14
25538043-2	2015	Thioglycollate-induced neutrophil recruitment into the peritoneum was more severely impaired in P-Rex1(-/-) Vav1(-/-) (P1V1) or P-Rex1(-/-) Vav3(-/-) (P1V3) mice than in P-Rex null or Vav null mice, suggesting cooperation between P-Rex and Vav Rac-GEFs in this process.	Thioglycolates	0-14	vav 3 oncogene	Mus musculus	128-144
25538043-2	2015	Thioglycollate-induced neutrophil recruitment into the peritoneum was more severely impaired in P-Rex1(-/-) Vav1(-/-) (P1V1) or P-Rex1(-/-) Vav3(-/-) (P1V3) mice than in P-Rex null or Vav null mice, suggesting cooperation between P-Rex and Vav Rac-GEFs in this process.	Thioglycolates	0-14	vav 1 oncogene	Mus musculus	108-111
25538043-2	2015	Thioglycollate-induced neutrophil recruitment into the peritoneum was more severely impaired in P-Rex1(-/-) Vav1(-/-) (P1V1) or P-Rex1(-/-) Vav3(-/-) (P1V3) mice than in P-Rex null or Vav null mice, suggesting cooperation between P-Rex and Vav Rac-GEFs in this process.	Thioglycolates	0-14	vav 1 oncogene	Mus musculus	140-143
24985477-5	2014	Thioglycollate-induced macrophages (mps) were collected and cultured with lipopolysaccharide (LPS), IFN-gamma, and anti-mouse podoplanin antibody (PMab-1).	Thioglycolates	0-14	interferon gamma	Mus musculus	100-109
25328047-6	2015	Our results reveal that IL-4 induces phosphorylation of p38 MAPK in thioglycollate-elicited murine peritoneal macrophages, in addition to STAT-6 and PI3K activation.	Thioglycolates	68-82	interleukin 4	Mus musculus	24-28
25328047-6	2015	Our results reveal that IL-4 induces phosphorylation of p38 MAPK in thioglycollate-elicited murine peritoneal macrophages, in addition to STAT-6 and PI3K activation.	Thioglycolates	68-82	mitogen-activated protein kinase 14	Mus musculus	56-64
25255441-6	2014	Here, we used thioglycollate-elicited primary mouse peritoneal macrophages (MPMPhi) from Abcd1 and Abcd2 single- and double-deficient mice to establish how these mutations affect VLCFA metabolism.	Thioglycolates	14-28	ATP-binding cassette, sub-family D (ALD), member 2	Mus musculus	99-104
25130466-3	2014	RESULTS: We observed intense inflammatory response (CD45 and CD68 expression) and mtDNA damage in spleen and kidneys of WT mice given thioglycollate.	Thioglycolates	134-148	protein tyrosine phosphatase, receptor type, C	Mus musculus	52-56
25130466-3	2014	RESULTS: We observed intense inflammatory response (CD45 and CD68 expression) and mtDNA damage in spleen and kidneys of WT mice given thioglycollate.	Thioglycolates	134-148	CD68 antigen	Mus musculus	61-65
24981766-8	2014	Intraperitoneal administration of imatinib, a potent inhibitor of PDGFRbeta, and transduction of PDGFRbeta/Fc chimeric protein by an adenoviral system both reduced inflammatory lymphangiogenesis induced by thioglycollate in mice.	Thioglycolates	206-220	platelet derived growth factor receptor, beta polypeptide	Mus musculus	97-106
25272939-5	2014	METHODS: LPS and ATP were used to stimulate the release of IL-1beta from thioglycollate-elicited macrophages from BALB/c mice.	Thioglycolates	73-87	interleukin 1 beta	Mus musculus	59-67
25272939-7	2014	RESULTS: In cultured thioglycollate-elicited macrophages, we observed that LPS + ATP greatly enhanced IL-1 beta secretion (6938.00 +/- 83.45; P < 0.05) and the mRNA levels of NALP3, caspase-1 which are two main components of NALP3 inflammasome (60.88 +/- 8.28; 1.31 +/- 0.04, P < 0.05 for both).	Thioglycolates	21-35	interleukin 1 beta	Mus musculus	102-111
25272939-7	2014	RESULTS: In cultured thioglycollate-elicited macrophages, we observed that LPS + ATP greatly enhanced IL-1 beta secretion (6938.00 +/- 83.45; P < 0.05) and the mRNA levels of NALP3, caspase-1 which are two main components of NALP3 inflammasome (60.88 +/- 8.28; 1.31 +/- 0.04, P < 0.05 for both).	Thioglycolates	21-35	NLR family, pyrin domain containing 3	Mus musculus	178-183
25272939-7	2014	RESULTS: In cultured thioglycollate-elicited macrophages, we observed that LPS + ATP greatly enhanced IL-1 beta secretion (6938.00 +/- 83.45; P < 0.05) and the mRNA levels of NALP3, caspase-1 which are two main components of NALP3 inflammasome (60.88 +/- 8.28; 1.31 +/- 0.04, P < 0.05 for both).	Thioglycolates	21-35	caspase 1	Mus musculus	185-194
25272939-7	2014	RESULTS: In cultured thioglycollate-elicited macrophages, we observed that LPS + ATP greatly enhanced IL-1 beta secretion (6938.00 +/- 83.45; P < 0.05) and the mRNA levels of NALP3, caspase-1 which are two main components of NALP3 inflammasome (60.88 +/- 8.28; 1.31 +/- 0.04, P < 0.05 for both).	Thioglycolates	21-35	NLR family, pyrin domain containing 3	Mus musculus	228-233
24627994-5	2014	To further dissect the mechanisms regulating CD13-dependent trafficking we used the murine model of thioglycollate-induced sterile peritonitis.	Thioglycolates	100-114	alanyl (membrane) aminopeptidase	Mus musculus	45-49
24627994-7	2014	Furthermore, adoptive transfer of wild-type and CD13(KO) primary myeloid cells, or wild-type myeloid cells pre-treated with CD13-blocking antibodies into thioglycollate-challenged wild-type recipients demonstrated fewer CD13(KO) or treated cells in the lavage, suggesting that CD13 expression confers a competitive advantage in trafficking.	Thioglycolates	154-168	alanyl (membrane) aminopeptidase	Mus musculus	48-52
24627994-7	2014	Furthermore, adoptive transfer of wild-type and CD13(KO) primary myeloid cells, or wild-type myeloid cells pre-treated with CD13-blocking antibodies into thioglycollate-challenged wild-type recipients demonstrated fewer CD13(KO) or treated cells in the lavage, suggesting that CD13 expression confers a competitive advantage in trafficking.	Thioglycolates	154-168	alanyl (membrane) aminopeptidase	Mus musculus	124-128
24627994-7	2014	Furthermore, adoptive transfer of wild-type and CD13(KO) primary myeloid cells, or wild-type myeloid cells pre-treated with CD13-blocking antibodies into thioglycollate-challenged wild-type recipients demonstrated fewer CD13(KO) or treated cells in the lavage, suggesting that CD13 expression confers a competitive advantage in trafficking.	Thioglycolates	154-168	alanyl (membrane) aminopeptidase	Mus musculus	124-128
24627994-7	2014	Furthermore, adoptive transfer of wild-type and CD13(KO) primary myeloid cells, or wild-type myeloid cells pre-treated with CD13-blocking antibodies into thioglycollate-challenged wild-type recipients demonstrated fewer CD13(KO) or treated cells in the lavage, suggesting that CD13 expression confers a competitive advantage in trafficking.	Thioglycolates	154-168	alanyl (membrane) aminopeptidase	Mus musculus	124-128
25255441-6	2014	Here, we used thioglycollate-elicited primary mouse peritoneal macrophages (MPMPhi) from Abcd1 and Abcd2 single- and double-deficient mice to establish how these mutations affect VLCFA metabolism.	Thioglycolates	14-28	ATP-binding cassette, sub-family D (ALD), member 1	Mus musculus	89-94
24760994-0	2014	Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors.	Thioglycolates	0-15	free fatty acid receptor 1	Rattus norvegicus	92-97
24985477-5	2014	Thioglycollate-induced macrophages (mps) were collected and cultured with lipopolysaccharide (LPS), IFN-gamma, and anti-mouse podoplanin antibody (PMab-1).	Thioglycolates	0-14	podoplanin	Mus musculus	126-136
24746836-5	2014	Thioglycollate-elicited peritoneal macrophages were collected from wild-type and myeloid-cell-specific selenoprotein knockout mice to analyze oxylipid production by liquid chromatography/mass spectrometry as well as oxylipid biosynthetic enzyme and inflammatory marker gene expression by quantitative real-time polymerase chain reaction.	Thioglycolates	0-14	selenoprotein F	Mus musculus	103-116
24713702-7	2014	Consistent with impairments in chemokine receptor expression, tpl2(-/-) macrophages were defective in trafficking to the peritoneal cavity following thioglycollate-induced inflammation.	Thioglycolates	149-163	mitogen-activated protein kinase kinase kinase 8	Mus musculus	62-66
23784457-4	2013	Thioglycolate-induced peritoneal macrophages were prepared from BALB/c mice and cultured for 24 h in the presence of the hsp70.	Thioglycolates	0-13	heat shock protein 1B	Mus musculus	121-126
24329519-4	2014	Monitoring of TNF-alpha-induced expression of the adhesion molecules VCAM-1, ICAM-1 and E-selectin by flow cytometry was used to confirm NF-kappaB inhibition in endothelial cells, and thioglycollate-induced peritonitis in mice to confirm effects in vivo.	Thioglycolates	184-198	tumor necrosis factor	Mus musculus	14-23
24329519-6	2014	KEY RESULTS: Plumericin inhibited NF-kappaB-mediated transactivation of a luciferase reporter gene (IC50 1 muM), abolished TNF-alpha-induced expression of the adhesion molecules VCAM-1, ICAM-1 and E-selectin in endothelial cells and suppressed thioglycollate-induced peritonitis in mice.	Thioglycolates	244-258	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	34-43
24569077-8	2014	In addition, the inflammation-induced migration of macrophages was greatly reduced in clusterin-deficient mice based on a thioglycollate-induced peritonitis model system.	Thioglycolates	122-136	clusterin	Mus musculus	86-95
24163073-4	2014	Thioglycollate, used for macrophage elicitation, selectively upregulated PPARgamma and its target gene CD36 in peritoneal macrophages of both wild-type (WT) and Alox15(-/-) mice.	Thioglycolates	0-14	peroxisome proliferator activated receptor gamma	Mus musculus	73-82
24163073-4	2014	Thioglycollate, used for macrophage elicitation, selectively upregulated PPARgamma and its target gene CD36 in peritoneal macrophages of both wild-type (WT) and Alox15(-/-) mice.	Thioglycolates	0-14	arachidonate 15-lipoxygenase	Mus musculus	161-167
24163073-5	2014	Moreover, thioglycollate-injected Alox15(-/-) mice became hypertensive upon L-NAME treatment.	Thioglycolates	10-24	arachidonate 15-lipoxygenase	Mus musculus	34-40
24163073-6	2014	A similar hypertensive effect was observed with adoptive transfer of thioglycollate-elicited Alox15(-/-) macrophages into Alox15(-/-) recipient mice.	Thioglycolates	69-83	arachidonate 15-lipoxygenase	Mus musculus	93-99
24163073-6	2014	A similar hypertensive effect was observed with adoptive transfer of thioglycollate-elicited Alox15(-/-) macrophages into Alox15(-/-) recipient mice.	Thioglycolates	69-83	arachidonate 15-lipoxygenase	Mus musculus	122-128
24163073-9	2014	The PPARgamma antagonist treatment also prevented L-NAME-induced hypertension in thioglycollate-injected Alox15(-/-) mice, indicating a PPARgamma-mediated effect in macrophage elicitation and the resultant hypertension.	Thioglycolates	81-95	peroxisome proliferator activated receptor gamma	Mus musculus	4-13
24163073-9	2014	The PPARgamma antagonist treatment also prevented L-NAME-induced hypertension in thioglycollate-injected Alox15(-/-) mice, indicating a PPARgamma-mediated effect in macrophage elicitation and the resultant hypertension.	Thioglycolates	81-95	arachidonate 15-lipoxygenase	Mus musculus	105-111
24163073-9	2014	The PPARgamma antagonist treatment also prevented L-NAME-induced hypertension in thioglycollate-injected Alox15(-/-) mice, indicating a PPARgamma-mediated effect in macrophage elicitation and the resultant hypertension.	Thioglycolates	81-95	peroxisome proliferator activated receptor gamma	Mus musculus	136-145
24278484-7	2013	We next determined in vivo impacts of IL-4 and IFNgamma on the development of neutrophil-DC hybrids in thioglycollate-induced peritonitis lesions.	Thioglycolates	103-117	interleukin 4	Mus musculus	38-42
24278484-7	2013	We next determined in vivo impacts of IL-4 and IFNgamma on the development of neutrophil-DC hybrids in thioglycollate-induced peritonitis lesions.	Thioglycolates	103-117	interferon gamma	Mus musculus	47-55
24371083-7	2014	Importantly, in LDLR(-/-) mice, platelet depletion resulted in a significant decrease of peritoneal macrophage recruitment and foam cell formation in a thioglycollate-elicited peritonitis model.	Thioglycolates	152-166	low density lipoprotein receptor	Mus musculus	16-20
23318789-9	2013	Finally, the observed in vitro effects were confirmed in an in vivo inflammatory model, in which subcutaneous injection of AANO2 was able to decrease NOX2 activity in macrophages from thioglycolate-treated mice.	Thioglycolates	184-197	cytochrome b-245, beta polypeptide	Mus musculus	150-154
23817563-9	2013	Finally, in in vivo models of inflammation, including thioglycolate-induced acute peritonitis and acute lung injury, infiltrating Ly6G(+) neutrophils, expressed IL-1R2.	Thioglycolates	54-67	lymphocyte antigen 6 complex, locus G	Mus musculus	130-134
23817563-9	2013	Finally, in in vivo models of inflammation, including thioglycolate-induced acute peritonitis and acute lung injury, infiltrating Ly6G(+) neutrophils, expressed IL-1R2.	Thioglycolates	54-67	interleukin 1 receptor, type II	Mus musculus	161-167
23853092-3	2013	Of the classical Hdacs, Hdac7 was expressed at elevated levels in inflammatory macrophages (thioglycollate-elicited peritoneal macrophages) as compared with bone marrow-derived macrophages and the RAW264 cell line.	Thioglycolates	92-106	histone deacetylase 7	Mus musculus	24-29
23853092-5	2013	A novel class IIa-selective HDAC inhibitor reduced recombinant human HDAC7 enzyme activity as well as TLR-induced production of inflammatory mediators in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	154-168	histone deacetylase 9	Homo sapiens	28-32
23733875-3	2013	Upon thioglycolate challenge, CD11b(+) F4/80(+) macrophages showed a diminished ability to migrate to the peritoneal cavity in cox-2(-/-) mice.	Thioglycolates	5-18	integrin alpha M	Mus musculus	30-35
23733875-3	2013	Upon thioglycolate challenge, CD11b(+) F4/80(+) macrophages showed a diminished ability to migrate to the peritoneal cavity in cox-2(-/-) mice.	Thioglycolates	5-18	cytochrome c oxidase II, mitochondrial	Mus musculus	127-132
24002019-5	2013	KEY FINDINGS: In thioglycollate-elicited macrophages, increased proportion of ED1+ cells was accompanied with elevated phagocytosis of zymosan (DA strain), whereas increased expression level of CD86 molecule on ED2+ macrophages matched elevated secretory capacity for H2O2, TNF-alpha and NO (AO rats).	Thioglycolates	17-31	CD86 molecule	Rattus norvegicus	194-198
24002019-5	2013	KEY FINDINGS: In thioglycollate-elicited macrophages, increased proportion of ED1+ cells was accompanied with elevated phagocytosis of zymosan (DA strain), whereas increased expression level of CD86 molecule on ED2+ macrophages matched elevated secretory capacity for H2O2, TNF-alpha and NO (AO rats).	Thioglycolates	17-31	tumor necrosis factor	Rattus norvegicus	274-283
23863407-8	2013	Meiotic resumption induced by follicle-stimulating hormone (FSH) or amphiregulin was completely inhibited by the FAO inhibitors etomoxir, mercaptoacetate, and malonyl CoA.	Thioglycolates	138-153	amphiregulin	Mus musculus	68-80
23623936-10	2013	In response to thioglycollate stimulation, Gsr-deficient mice mobilized far fewer phagocytes, including neutrophils, macrophages, and eosinophils, into their peritoneal cavities than did wild-type mice.	Thioglycolates	15-29	gutter shaped root	Mus musculus	43-46
23192608-10	2013	We generated chimeric mice expressing mutated forms of OPN in myeloid-derived leukocytes, and found that the SLAYGLR functional domain of OPN, but not the RGD, mediates macrophage accumulation in response to thioglycollate-elicited peritonitis.	Thioglycolates	208-222	secreted phosphoprotein 1	Mus musculus	138-141
23648861-3	2013	Intriguingly, all mild reducing agents examined including mercaptoethanesulfonic acid (MESNA), thiolactic acid (TLA), and thioglycolate (TG) were shown to block apoptosis and increase EPO production.	Thioglycolates	122-135	erythropoietin	Cricetulus griseus	184-187
23041326-8	2013	IL-8 was strongly up-regulated on systemic or local inflammatory stimulation, increasing mobilization of immature CD11b(+)Gr-1(+) myeloid cells (IMCs) with thioglycolate-induced peritonitis, DSS-induced colitis, and H. felis-induced gastritis.	Thioglycolates	156-169	C-X-C motif chemokine ligand 8	Homo sapiens	0-4
23648861-3	2013	Intriguingly, all mild reducing agents examined including mercaptoethanesulfonic acid (MESNA), thiolactic acid (TLA), and thioglycolate (TG) were shown to block apoptosis and increase EPO production.	Thioglycolates	137-139	erythropoietin	Cricetulus griseus	184-187
23349186-7	2013	Furthermore, Atox1(-/-) mice show decreased perivascular macrophage infiltration in wire-injured vessels, as well as thioglycollate-induced peritoneal macrophage recruitment.	Thioglycolates	117-131	antioxidant 1 copper chaperone	Mus musculus	13-18
23341579-6	2013	Moreover, in thioglycollate-elicited Nrf2(-/-) macrophages, the uptake of acetylated and malondialdehyde-modified LDLs was increased in comparison with WT controls, with the concomitant increase in the expression of scavenger receptor A and toll-like receptor 4.	Thioglycolates	13-27	nuclear factor, erythroid derived 2, like 2	Mus musculus	37-41
23392941-5	2013	Also, when TauCl was injected in combination with 3% thioglycolate, HO-1 expression in the peritoneal macrophages was increased.	Thioglycolates	53-66	heme oxygenase 1	Mus musculus	68-72
22925810-5	2013	In the present study, we investigated the effects of IL-27 on NO production in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	79-93	interleukin 27	Homo sapiens	53-58
23041326-8	2013	IL-8 was strongly up-regulated on systemic or local inflammatory stimulation, increasing mobilization of immature CD11b(+)Gr-1(+) myeloid cells (IMCs) with thioglycolate-induced peritonitis, DSS-induced colitis, and H. felis-induced gastritis.	Thioglycolates	156-169	integrin subunit alpha M	Homo sapiens	114-119
23146878-13	2013	In the thioglycollate-induced peritoneal monocyte infiltration model, mice were challenged with 3% thioglycollate, and 2 h later peritoneal lavage fluid was collected for MCP-1 analysis.	Thioglycolates	7-21	chemokine (C-C motif) ligand 2	Mus musculus	171-176
23146878-16	2013	Doxazosin decreased the level of MCP-1 release in the peritoneal cavity of thioglycollate-stimulated animals, though this effect was not statistically significant.	Thioglycolates	75-89	chemokine (C-C motif) ligand 2	Mus musculus	33-38
23383297-10	2013	In vivo foam cell formation was evaluated in thioglycollate-elicited peritoneal macrophages from 11betaHSD1+/+/apoE-/- and 11betaHSD1-/-/apoE-/- mice fed a Western diet for ~5 weeks.	Thioglycolates	45-59	hydroxysteroid 11-beta dehydrogenase 1	Mus musculus	97-107
23383297-10	2013	In vivo foam cell formation was evaluated in thioglycollate-elicited peritoneal macrophages from 11betaHSD1+/+/apoE-/- and 11betaHSD1-/-/apoE-/- mice fed a Western diet for ~5 weeks.	Thioglycolates	45-59	apolipoprotein E	Mus musculus	111-115
22732454-9	2012	Intriguingly, ASX was capable of inducing PPARgamma target genes such as liver X receptor, CD36 and ABCA1 in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	109-123	peroxisome proliferator activated receptor gamma	Mus musculus	42-51
22885069-4	2012	Knockdown of TMEM126A also blocked the down-regulation of IL-1beta and IL-6 expressions induced by CD137L in thioglycollate-elicited primary peritoneal macrophages.	Thioglycolates	109-123	transmembrane protein 126A	Mus musculus	13-21
22885069-4	2012	Knockdown of TMEM126A also blocked the down-regulation of IL-1beta and IL-6 expressions induced by CD137L in thioglycollate-elicited primary peritoneal macrophages.	Thioglycolates	109-123	interleukin 1 beta	Mus musculus	58-66
22885069-4	2012	Knockdown of TMEM126A also blocked the down-regulation of IL-1beta and IL-6 expressions induced by CD137L in thioglycollate-elicited primary peritoneal macrophages.	Thioglycolates	109-123	interleukin 6	Mus musculus	71-75
22885069-4	2012	Knockdown of TMEM126A also blocked the down-regulation of IL-1beta and IL-6 expressions induced by CD137L in thioglycollate-elicited primary peritoneal macrophages.	Thioglycolates	109-123	tumor necrosis factor (ligand) superfamily, member 9	Mus musculus	99-105
24900425-6	2012	In a thioglycollate-induced inflammation model in hCCR2KI mice, it had ED50 of 3 mg/kg on inhibition of the influx of leukocytes, monocytes/macrophages, and T-lymphocytes.	Thioglycolates	5-19	C-C motif chemokine receptor 2	Homo sapiens	50-55
22257935-3	2013	We hypothesised that gene therapy with BRCA1, a critical regulator of DNA damage repair and cell survival, would attenuate the sequelae of sepsis and peritonitis in mice subjected to caecal ligation and perforation (CLP) and thioglycollate stimulation.	Thioglycolates	225-239	breast cancer 1, early onset	Mus musculus	39-44
22844112-8	2012	Moreover, phagocytosis of apoptotic PR3-expressing cells potentiated proinflammatory cytokine in vitro by human monocyte-derived macrophages and in vivo by resident murine peritoneal macrophages, and diverted the anti-inflammatory response triggered by the phagocytosis of apoptotic cells after LPS challenge in thioglycolate-elicited murine macrophages.	Thioglycolates	312-325	proteinase 3	Homo sapiens	36-39
22194623-7	2012	Furthermore, Nur77(-/-) mice show enhanced thioglycollate-elicited migration of macrophages and B cells.	Thioglycolates	43-57	nuclear receptor subfamily 4, group A, member 1	Mus musculus	13-18
22706085-5	2012	Galpha(i2)-deficient but not wild-type or Galpha(i3)-deficient mice exhibited reduced recruitment of macrophages in experimental models of thioglycollate-induced peritonitis and LPS-triggered lung injury.	Thioglycolates	139-153	guanine nucleotide binding protein (G protein), alpha inhibiting 2	Mus musculus	0-9
22018663-10	2012	To further characterize our observations we studied thioglycolate-elicited peritoneal macrophages from gp130(DeltaLys) animals.	Thioglycolates	52-65	interleukin 6 cytokine family signal transducer	Homo sapiens	103-108
22445881-10	2012	In peritoneal exuded macrophages induced by thioglycollate, BTB09089 suppressed the production of TNF-alpha and IL-6 while it increased that of IL-10 when stimulated with lipopolysaccharide.	Thioglycolates	44-58	tumor necrosis factor	Mus musculus	98-107
22445881-10	2012	In peritoneal exuded macrophages induced by thioglycollate, BTB09089 suppressed the production of TNF-alpha and IL-6 while it increased that of IL-10 when stimulated with lipopolysaccharide.	Thioglycolates	44-58	interleukin 6	Mus musculus	112-116
22445881-10	2012	In peritoneal exuded macrophages induced by thioglycollate, BTB09089 suppressed the production of TNF-alpha and IL-6 while it increased that of IL-10 when stimulated with lipopolysaccharide.	Thioglycolates	44-58	interleukin 10	Mus musculus	144-149
22442441-4	2012	Moreover, in a thioglycollate-induced peritonitis mouse model, Sema4A was detected in circulating Ly6C(high) inflammatory monocytes and peritoneal macrophages.	Thioglycolates	15-29	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	Mus musculus	63-69
22442441-4	2012	Moreover, in a thioglycollate-induced peritonitis mouse model, Sema4A was detected in circulating Ly6C(high) inflammatory monocytes and peritoneal macrophages.	Thioglycolates	15-29	lymphocyte antigen 6 complex, locus C1	Mus musculus	98-102
22403440-7	2012	Prkcq(-/-) neutrophil recruitment was impaired in fMLP-induced transmigration into the cremaster muscle, thioglycollate-induced peritonitis, and LPS-induced lung injury.	Thioglycolates	105-119	protein kinase C, theta	Mus musculus	0-5
21781347-6	2011	METHODS: Thioglycolate-elicited rat peritoneal macrophages were loaded with myelin and cocultured with myelin-basic protein (MBP) or ovalbumin (OVA) reactive lymphocytes.	Thioglycolates	9-22	myelin basic protein	Rattus norvegicus	103-123
21940822-9	2011	In a mouse model of thioglycollate-induced peritonitis, anti-Plg-R(KT) mAb markedly inhibited macrophage recruitment (by 58%), concomitant with a reduction in pro-MMP-9 activation in the inflamed peritoneum.	Thioglycolates	20-34	plasminogen receptor, C-terminal lysine transmembrane protein	Mus musculus	61-69
21911487-7	2011	This increased neutrophil recruitment was also observed in LPS- and thioglycollate (TG)-induced inflammation in Mgat5(-/-) mice.	Thioglycolates	68-82	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-7	2011	This increased neutrophil recruitment was also observed in LPS- and thioglycollate (TG)-induced inflammation in Mgat5(-/-) mice.	Thioglycolates	84-86	mannoside acetylglucosaminyltransferase 5	Mus musculus	112-117
21911487-8	2011	Furthermore, there was significantly increased recruitment of infused Mgat5(-/-) neutrophils compared with WT neutrophils in the peritoneal cavity of TG-exposed WT mice.	Thioglycolates	150-152	mannoside acetylglucosaminyltransferase 5	Mus musculus	70-75
21885429-7	2011	Although ABHD5 expression was elevated in thioglycolate-elicited macrophages from ABHD5 transgenic mice, Toll-like receptor 4 (TLR4) signaling was comparable in macrophages isolated from ABHD5 transgenic and WT mice.	Thioglycolates	42-55	abhydrolase domain containing 5	Mus musculus	9-14
21885429-7	2011	Although ABHD5 expression was elevated in thioglycolate-elicited macrophages from ABHD5 transgenic mice, Toll-like receptor 4 (TLR4) signaling was comparable in macrophages isolated from ABHD5 transgenic and WT mice.	Thioglycolates	42-55	abhydrolase domain containing 5	Mus musculus	82-87
21885429-7	2011	Although ABHD5 expression was elevated in thioglycolate-elicited macrophages from ABHD5 transgenic mice, Toll-like receptor 4 (TLR4) signaling was comparable in macrophages isolated from ABHD5 transgenic and WT mice.	Thioglycolates	42-55	abhydrolase domain containing 5	Mus musculus	82-87
21807912-9	2011	Finally, upon in vitro stimulation with A. fumigatus, thioglycolate-elicited peritoneal neutrophils were positive for intracellular IL-17A expression and produced IL-17A in a Dectin-1- and IL-23-dependent manner.	Thioglycolates	54-67	interleukin 17A	Mus musculus	132-138
21807912-9	2011	Finally, upon in vitro stimulation with A. fumigatus, thioglycolate-elicited peritoneal neutrophils were positive for intracellular IL-17A expression and produced IL-17A in a Dectin-1- and IL-23-dependent manner.	Thioglycolates	54-67	interleukin 17A	Mus musculus	163-169
21807912-9	2011	Finally, upon in vitro stimulation with A. fumigatus, thioglycolate-elicited peritoneal neutrophils were positive for intracellular IL-17A expression and produced IL-17A in a Dectin-1- and IL-23-dependent manner.	Thioglycolates	54-67	C-type lectin domain family 7, member a	Mus musculus	175-183
21807912-9	2011	Finally, upon in vitro stimulation with A. fumigatus, thioglycolate-elicited peritoneal neutrophils were positive for intracellular IL-17A expression and produced IL-17A in a Dectin-1- and IL-23-dependent manner.	Thioglycolates	54-67	interleukin 23, alpha subunit p19	Mus musculus	189-194
21849679-6	2011	C1q-hemolytic activity in CD93(-/-) mice was decreased by 22% at time zero and by 46% 3 h after thioglycollate injection, suggesting a defect in the classical complement pathway.	Thioglycolates	96-110	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	0-3
21849679-6	2011	C1q-hemolytic activity in CD93(-/-) mice was decreased by 22% at time zero and by 46% 3 h after thioglycollate injection, suggesting a defect in the classical complement pathway.	Thioglycolates	96-110	CD93 antigen	Mus musculus	26-30
21774078-7	2011	Consistently, administration of QC-inhibitors in inflammatory models, such as thioglycollate-induced peritonitis reduced monocyte infiltration.	Thioglycolates	78-92	glutaminyl-peptide cyclotransferase (glutaminyl cyclase)	Mus musculus	32-34
22768214-7	2012	Peritoneal macrophages from WT mice, recruited by thioglycolate or polyacrylamide beads, functionally expressed ChemR23, as assessed by flow cytometry, binding and chemotaxis assays.	Thioglycolates	50-63	chemokine-like receptor 1	Mus musculus	112-119
22427969-8	2012	Finally, although CD44 antibodies were able to augment phagocytosis of apoptotic neutrophils by murine peritoneal and bone marrow-derived macrophages, we did not observe a difference in the clearance of neutrophils following induction of peritonitis with thioglycollate in CD44-deficient animals.	Thioglycolates	255-269	CD44 antigen	Mus musculus	18-22
22185406-6	2011	RESULTS: Thioglycolate-elicited peritoneal macrophages prepared after four weeks of feeding, and then challenged with LPS (10 ng or 100 ng) resulted in increases of 55% and 73%, respectively in the production of NO of 46-week-old compared to 8-week-old mice fed control diet alone (respective control groups), without affecting the secretion of TNF-alpha among these two groups.	Thioglycolates	9-22	tumor necrosis factor	Mus musculus	345-354
21849679-4	2011	In this study, we demonstrate heightened susceptibility to thioglycollate-induced peritonitis in CD93(-/-) mice.	Thioglycolates	59-73	CD93 antigen	Mus musculus	97-101
21849679-5	2011	CD93(-/-) mice showed a 1.6-1.8-fold increase in leukocyte infiltration during thioglycollate-induced peritonitis between 3 and 24 h that returned to wild type levels by 96 h. Impaired vascular integrity in CD93(-/-) mice during peritonitis was demonstrated using fluorescence multiphoton intravital microscopy; however, no differences in cytokine or chemokine levels were detected with Luminex Multiplex or ELISA analysis.	Thioglycolates	79-93	CD93 antigen	Mus musculus	0-4
21849679-5	2011	CD93(-/-) mice showed a 1.6-1.8-fold increase in leukocyte infiltration during thioglycollate-induced peritonitis between 3 and 24 h that returned to wild type levels by 96 h. Impaired vascular integrity in CD93(-/-) mice during peritonitis was demonstrated using fluorescence multiphoton intravital microscopy; however, no differences in cytokine or chemokine levels were detected with Luminex Multiplex or ELISA analysis.	Thioglycolates	79-93	CD93 antigen	Mus musculus	207-211
21562126-9	2011	CD11b(+)Gr-1(+) macrophages obtained from Gal-9-treated but not PBS-treated mice suppressed TNF-alpha and keratinocyte-derived cytokine production from LPS-stimulated macrophages, and down-regulated Toll-like receptor-4 (TLR4) and TLR2 expression on thioglycollate-elicited macrophages.	Thioglycolates	250-264	integrin alpha M	Mus musculus	0-5
21562126-9	2011	CD11b(+)Gr-1(+) macrophages obtained from Gal-9-treated but not PBS-treated mice suppressed TNF-alpha and keratinocyte-derived cytokine production from LPS-stimulated macrophages, and down-regulated Toll-like receptor-4 (TLR4) and TLR2 expression on thioglycollate-elicited macrophages.	Thioglycolates	250-264	lectin, galactose binding, soluble 9	Mus musculus	42-47
21781347-6	2011	METHODS: Thioglycolate-elicited rat peritoneal macrophages were loaded with myelin and cocultured with myelin-basic protein (MBP) or ovalbumin (OVA) reactive lymphocytes.	Thioglycolates	9-22	myelin basic protein	Rattus norvegicus	125-128
21628404-2	2011	In this study, we show that Adam17-null neutrophils have a 2-fold advantage in their initial recruitment during thioglycollate-induced peritonitis, and they roll slower and adhere more readily in the cremaster model than wild-type neutrophils.	Thioglycolates	112-126	ADAM metallopeptidase domain 17	Homo sapiens	28-34
21625821-3	2011	Upon stimulation with lipopolysaccharide (LPS), resident and thioglycolate-elicited PMPhi from young mice presented higher iNOS activity than those from old mice (54.4%).	Thioglycolates	61-74	nitric oxide synthase 2, inducible	Mus musculus	123-127
21264853-3	2011	In thioglycollate-induced peritonitis, the number of neutrophils and monocytes was significantly diminished in Thy-1-deficient mice.	Thioglycolates	3-17	thymus cell antigen 1, theta	Mus musculus	111-116
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	Mus musculus	54-58
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	Mus musculus	60-64
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	proteasome (prosome, macropain) subunit, beta type 10	Mus musculus	73-79
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	Mus musculus	86-90
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	proteasome (prosome, macropain) subunit, beta type 10	Mus musculus	91-97
21455681-4	2011	Accordingly, thioglycollate-elicited macrophages from LMP7, LMP2, LMP10 (MECL-1), and LMP7/MECL-1 double knockout mice were stimulated in vitro with LPS, and were found to generate markedly reduced NO levels compared to wild-type (WT) mice, whereas TNF-alpha levels responses were essentially unaltered relative to wild-type responses.	Thioglycolates	13-27	tumor necrosis factor	Mus musculus	249-258
21419839-2	2011	We found that short treatment (3.5h) of macrophage-like J774 cells and thioglycollate-elicited peritoneal murine macrophages with ManLAM and its deacylated form enhanced LPS-stimulated release of tumor necrosis factor-alpha (TNF-alpha).	Thioglycolates	71-85	tumor necrosis factor	Mus musculus	196-223
21419839-2	2011	We found that short treatment (3.5h) of macrophage-like J774 cells and thioglycollate-elicited peritoneal murine macrophages with ManLAM and its deacylated form enhanced LPS-stimulated release of tumor necrosis factor-alpha (TNF-alpha).	Thioglycolates	71-85	tumor necrosis factor	Mus musculus	225-234
21184130-0	2011	Cross-linking of CD137 ligand modulates immune responses of thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	60-74	tumor necrosis factor receptor superfamily, member 9	Mus musculus	17-22
21184130-1	2011	OBJECTIVE: The aim of this study was to investigate effects of CD137 ligand (CD137L)-mediated reverse signaling on cellular responses in thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	137-151	tumor necrosis factor receptor superfamily, member 9	Mus musculus	63-68
21184130-1	2011	OBJECTIVE: The aim of this study was to investigate effects of CD137 ligand (CD137L)-mediated reverse signaling on cellular responses in thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	137-151	tumor necrosis factor (ligand) superfamily, member 9	Mus musculus	77-83
21184130-6	2011	RESULTS: Cross-linking of CD137L with recombinant CD137-Fc protein (rCD137-Fc) increased total numbers of thioglycollate-elicited mouse peritoneal macrophages (hIgG-Fc- vs. rCD137-Fc-treated group, p < 0.05).	Thioglycolates	106-120	tumor necrosis factor (ligand) superfamily, member 9	Mus musculus	26-32
21184130-6	2011	RESULTS: Cross-linking of CD137L with recombinant CD137-Fc protein (rCD137-Fc) increased total numbers of thioglycollate-elicited mouse peritoneal macrophages (hIgG-Fc- vs. rCD137-Fc-treated group, p < 0.05).	Thioglycolates	106-120	tumor necrosis factor receptor superfamily, member 9	Mus musculus	26-31
21184130-9	2011	CONCLUSION: Reverse signals initiated by CD137L negatively modulate certain immune functions of thioglycollate-elicited peritoneal macrophages.	Thioglycolates	96-110	tumor necrosis factor (ligand) superfamily, member 9	Mus musculus	41-47
20716766-7	2010	Searching for possible effects downstream of leukocyte capture, we found that anti-VWF antibodies significantly inhibited thioglycollate-induced vascular permeability.	Thioglycolates	122-136	von Willebrand factor	Homo sapiens	83-86
21283724-4	2011	Truncation of the deubiquitinating domain of CYLD specifically in myelomonocytic cells impaired the development of lethal LPS-induced endotoxic shock and the accumulation of thioglycollate-elicited peritoneal macrophages.	Thioglycolates	174-188	CYLD lysine 63 deubiquitinase	Homo sapiens	45-49
21130984-5	2011	Additionally, the over exuberant inflammatory response elicited by thioglycollate challenge in gp91(phox) deficient mice is attenuated by CGS21680.	Thioglycolates	67-81	paired Ig-like receptor B	Mus musculus	95-99
21691049-8	2011	Both transcripts were detected constitutively in thioglycollate-elicited peritoneal neutrophils, whereas only Fpr-rs2 was detected in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	134-148	formyl peptide receptor 2	Mus musculus	110-117
21865767-4	2011	Systemic treatment with bortezomib was efficacious in the thioglycolate-induced MCP-1 production model, and the dinitrofluorobenzene-induced delayed-type hypersensitivity model.	Thioglycolates	58-71	mast cell protease 1	Mus musculus	80-85
21165565-7	2011	IFITM6 expression was induced in various macrophages, including splenic, thioglycollate-elicited, and bone marrow-derived macrophages, but not in T cells.	Thioglycolates	73-87	interferon induced transmembrane protein 6	Mus musculus	0-6
20976168-9	2010	Moreover, thioglycollate-induced peritoneal macrophage recruitment and ROS production were inhibited in IQGAP1(-/-) mice.	Thioglycolates	10-24	IQ motif containing GTPase activating protein 1	Mus musculus	104-110
20619281-4	2010	To test this hypothesis, we investigated whether mercaptoacetate (MA), an inhibitor of FA oxidation, could induce an activation of TGF-beta in the CSF and a decrease in SMA.	Thioglycolates	49-64	transforming growth factor, beta 1	Rattus norvegicus	131-139
20401626-3	2010	METHODS: Endotoxin tolerance was induced in the RAW264.7 cell line and thioglycolate-elicited murine peritoneal macrophages by incubation with 100 ng/ml LPS for 20 h. Macrophages without the pretreatment were set as control.	Thioglycolates	71-84	toll-like receptor 4	Mus musculus	153-156
20401626-8	2010	The mRNA expression of Gfi1 in endotoxin tolerant macrophages was higher than that of control in both RAW264.7 cells and thioglycolate-elicited murine peritoneal macrophages.	Thioglycolates	121-134	growth factor independent 1 transcription repressor	Mus musculus	23-27
20176806-5	2010	In thioglycolate-elicited macrophages, PPARgamma colocalizes with the hematopoietic transcription factor PU.1 in areas of open chromatin and histone acetylation, near a distinct set of immune genes in addition to a number of metabolic genes shared with adipocytes.	Thioglycolates	3-16	peroxisome proliferator activated receptor gamma	Mus musculus	39-48
20424186-3	2010	Using thioglycollate to induce a peritoneal inflammatory response, we demonstrate, for the first time, that compared with wild-type (WT) mice, macrophage migration across the peritoneal membrane into the peritoneal cavity in S100A10-deficient (S100A10(-/-)) mice was decreased by up to 53% at 24, 48, and 72 hours.	Thioglycolates	6-20	S100 calcium binding protein A10 (calpactin)	Mus musculus	225-232
20554954-3	2010	We show in this study that chronic E2 administration to ovariectomized mice significantly increased both cytokine (IL-1beta, IL-6, and TNF-alpha) and inducible NO synthase mRNA abundance in thioglycolate (TGC)-elicited macrophages.	Thioglycolates	190-203	interleukin 1 beta	Mus musculus	115-123
20554954-3	2010	We show in this study that chronic E2 administration to ovariectomized mice significantly increased both cytokine (IL-1beta, IL-6, and TNF-alpha) and inducible NO synthase mRNA abundance in thioglycolate (TGC)-elicited macrophages.	Thioglycolates	190-203	interleukin 6	Mus musculus	125-129
20554954-3	2010	We show in this study that chronic E2 administration to ovariectomized mice significantly increased both cytokine (IL-1beta, IL-6, and TNF-alpha) and inducible NO synthase mRNA abundance in thioglycolate (TGC)-elicited macrophages.	Thioglycolates	190-203	tumor necrosis factor	Mus musculus	135-144
20554954-3	2010	We show in this study that chronic E2 administration to ovariectomized mice significantly increased both cytokine (IL-1beta, IL-6, and TNF-alpha) and inducible NO synthase mRNA abundance in thioglycolate (TGC)-elicited macrophages.	Thioglycolates	190-203	nitric oxide synthase 2, inducible	Mus musculus	150-171
20836883-6	2010	RESULTS: MRL-677 is a CCR2 antagonist that is effective in blocking macrophage trafficking in a peritoneal thioglycollate model.	Thioglycolates	107-121	chemokine (C-C motif) receptor 2	Mus musculus	22-26
20662097-6	2010	In peritoneal M Phi from IL-33-stimulated mice, mRNA expression of M2 M Phi marker genes were increased compared with thioglycollate-elicited peritoneal M Phi.	Thioglycolates	118-132	interleukin 33	Mus musculus	25-30
20176806-5	2010	In thioglycolate-elicited macrophages, PPARgamma colocalizes with the hematopoietic transcription factor PU.1 in areas of open chromatin and histone acetylation, near a distinct set of immune genes in addition to a number of metabolic genes shared with adipocytes.	Thioglycolates	3-16	spleen focus forming virus (SFFV) proviral integration oncogene	Mus musculus	70-109
20018613-3	2010	In the current study, we demonstrate that incubation of Prx1 with thioglycollate-elicited murine macrophages or immature bone marrow-derived dendritic cells resulted in TLR4-dependent secretion of TNF-alpha and IL-6 and dendritic cell maturation.	Thioglycolates	66-80	peroxiredoxin 1	Mus musculus	56-60
20234092-5	2010	In vivo analysis indicated that after instillation of thioglycollate to cause aseptic inflammation and after administration of acetaminophen to induce liver damage, endogenous HSCs/HPCs were actively recruited to the peritoneum and liver, respectively, in WT but not Ccr2-/- mice.	Thioglycolates	54-68	chemokine (C-C motif) receptor 2	Mus musculus	267-271
20303465-6	2010	Several systemic inflammatory stimulators (tumor necrosis factor [TNFalpha], lipopolysaccharide, thioglycollate, and carageenan) given to control mice showed that the inflammatory promotion of TF expression by only pulmonary vein endothelium is not specific to the sickle cell disease model.	Thioglycolates	97-111	coagulation factor III	Mus musculus	193-195
20007243-7	2010	thioglycollate elicitation, eosinophils accounted for over 20% of the total peritoneal inflammatory cell pool in ST6Gal-1-deficient animals, which was threefold greater than in corresponding wild-type animals.	Thioglycolates	0-14	beta galactoside alpha 2,6 sialyltransferase 1	Mus musculus	113-121
20153221-4	2010	Exclusive CD95L deletion in myeloid cells greatly decreased the number of neutrophils and macrophages infiltrating the injured spinal cord or the inflamed peritoneum after thioglycollate injection.	Thioglycolates	172-186	Fas ligand	Homo sapiens	10-15
20112357-6	2010	Bim(-/-) mice were stimulated with thioglycollate or LPS and examined for macrophage activation and cytokine production.	Thioglycolates	35-49	BCL2-like 11 (apoptosis facilitator)	Mus musculus	0-3
20112357-11	2010	Bim(-/-) macrophages displayed elevated expression of markers of inflammation and secreted more interleukin-1beta following stimulation with LPS or thioglycollate.	Thioglycolates	148-162	BCL2-like 11 (apoptosis facilitator)	Mus musculus	0-3
20112357-11	2010	Bim(-/-) macrophages displayed elevated expression of markers of inflammation and secreted more interleukin-1beta following stimulation with LPS or thioglycollate.	Thioglycolates	148-162	interleukin 1 beta	Mus musculus	96-113
20018613-3	2010	In the current study, we demonstrate that incubation of Prx1 with thioglycollate-elicited murine macrophages or immature bone marrow-derived dendritic cells resulted in TLR4-dependent secretion of TNF-alpha and IL-6 and dendritic cell maturation.	Thioglycolates	66-80	toll-like receptor 4	Mus musculus	169-173
20018613-3	2010	In the current study, we demonstrate that incubation of Prx1 with thioglycollate-elicited murine macrophages or immature bone marrow-derived dendritic cells resulted in TLR4-dependent secretion of TNF-alpha and IL-6 and dendritic cell maturation.	Thioglycolates	66-80	tumor necrosis factor	Mus musculus	197-206
20018613-3	2010	In the current study, we demonstrate that incubation of Prx1 with thioglycollate-elicited murine macrophages or immature bone marrow-derived dendritic cells resulted in TLR4-dependent secretion of TNF-alpha and IL-6 and dendritic cell maturation.	Thioglycolates	66-80	interleukin 6	Mus musculus	211-215
20018613-5	2010	Binding of Prx1 to thioglycollate macrophages occurred within minutes and resulted in TLR4 endocytosis.	Thioglycolates	19-33	peroxiredoxin 1	Mus musculus	11-15
20018613-5	2010	Binding of Prx1 to thioglycollate macrophages occurred within minutes and resulted in TLR4 endocytosis.	Thioglycolates	19-33	toll-like receptor 4	Mus musculus	86-90
19180231-0	2009	PECAM-independent thioglycollate peritonitis is associated with a locus on murine chromosome 2.	Thioglycolates	18-32	platelet/endothelial cell adhesion molecule 1	Mus musculus	0-5
19596672-5	2009	Through selective expression of CB1 or CB2 to thioglycollate-elicited peritoneal macrophages, we proved that CB1 and CB2 mediate opposing influences on the production of reactive oxygen species (ROS).	Thioglycolates	46-60	cannabinoid receptor 1	Homo sapiens	32-35
19596672-5	2009	Through selective expression of CB1 or CB2 to thioglycollate-elicited peritoneal macrophages, we proved that CB1 and CB2 mediate opposing influences on the production of reactive oxygen species (ROS).	Thioglycolates	46-60	cannabinoid receptor 2	Homo sapiens	39-42
19596672-5	2009	Through selective expression of CB1 or CB2 to thioglycollate-elicited peritoneal macrophages, we proved that CB1 and CB2 mediate opposing influences on the production of reactive oxygen species (ROS).	Thioglycolates	46-60	cannabinoid receptor 1	Homo sapiens	109-112
19596672-5	2009	Through selective expression of CB1 or CB2 to thioglycollate-elicited peritoneal macrophages, we proved that CB1 and CB2 mediate opposing influences on the production of reactive oxygen species (ROS).	Thioglycolates	46-60	cannabinoid receptor 2	Homo sapiens	117-120
19749080-3	2009	In this study, we examined the signaling mechanisms by which A(2A)AR activation inhibits TNF-alpha production in thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	113-127	tumor necrosis factor	Mus musculus	89-98
19786552-7	2009	TNF or thioglycollate injection, neutrophil recruitment into the peritoneal cavity was reduced by more than 50% in FAN-deficient mice.	Thioglycolates	7-21	neutral sphingomyelinase (N-SMase) activation associated factor	Mus musculus	115-118
19641140-0	2009	Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A.	Thioglycolates	148-162	chemokine (C-C motif) ligand 2	Mus musculus	0-34
19641140-0	2009	Monocyte chemoattractant protein-1 (MCP-1), not MCP-3, is the primary chemokine required for monocyte recruitment in mouse peritonitis induced with thioglycollate or zymosan A.	Thioglycolates	148-162	chemokine (C-C motif) ligand 2	Mus musculus	36-41
19289519-6	2009	In addition, administration of L5 upregulated the expression of the Mig/CXCL9 chemokine gene in thioglycolate-elicited peritoneal macrophages.	Thioglycolates	96-109	chemokine (C-X-C motif) ligand 9	Mus musculus	68-71
18962899-5	2009	with recombinant GSTP1 protein effectively suppresses the devastating effects of acute inflammation, which includes reduction of mortality rate of endotoxic shock, alleviation of LPS-induced acute lung injury and abrogation of thioglycolate (TG)-induced peritoneal deposition of leukocytes and polymorphonuclear cells (PMNs).	Thioglycolates	227-240	glutathione S-transferase, pi 1	Mus musculus	17-22
18962899-5	2009	with recombinant GSTP1 protein effectively suppresses the devastating effects of acute inflammation, which includes reduction of mortality rate of endotoxic shock, alleviation of LPS-induced acute lung injury and abrogation of thioglycolate (TG)-induced peritoneal deposition of leukocytes and polymorphonuclear cells (PMNs).	Thioglycolates	242-244	glutathione S-transferase, pi 1	Mus musculus	17-22
19571604-2	2009	Thioglycolate-stimulated mouse peritoneal macrophages were induced to differentiate into dendritic cells by co-treatment with IL-4 and GM-CSF.	Thioglycolates	0-13	interleukin 4	Mus musculus	126-130
19571604-2	2009	Thioglycolate-stimulated mouse peritoneal macrophages were induced to differentiate into dendritic cells by co-treatment with IL-4 and GM-CSF.	Thioglycolates	0-13	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	135-141
19880493-3	2010	In this study, thioglycollate-elicited mouse peritoneal macrophages were treated with interleukin-4 (IL-4) or IL-13 in vitro and challenged with Neisseria meningitidis.	Thioglycolates	15-29	interleukin 4	Mus musculus	86-99
19880493-3	2010	In this study, thioglycollate-elicited mouse peritoneal macrophages were treated with interleukin-4 (IL-4) or IL-13 in vitro and challenged with Neisseria meningitidis.	Thioglycolates	15-29	interleukin 4	Mus musculus	101-105
19880493-3	2010	In this study, thioglycollate-elicited mouse peritoneal macrophages were treated with interleukin-4 (IL-4) or IL-13 in vitro and challenged with Neisseria meningitidis.	Thioglycolates	15-29	interleukin 13	Mus musculus	110-115
19772887-7	2009	However, GFP-expressing cells in thioglycollate-elicited peritoneal macrophages were also positive for F4/80 and monocyte-macrophage-specific 2 antigen.	Thioglycolates	33-47	adhesion G protein-coupled receptor E1	Mus musculus	103-108
19479052-9	2009	OGR1 deficient mice in the mixed background produced significantly less peritoneal macrophages when stimulated with thioglycolate.	Thioglycolates	116-129	G protein-coupled receptor 68	Mus musculus	0-4
19233845-4	2009	In mice, the GLEPP1 inhibitors also reduce thioglycolate-induced peritoneal chemotaxis of neutrophils, lymphocytes, and macrophages.	Thioglycolates	43-56	protein tyrosine phosphatase, receptor type, O	Mus musculus	13-19
18852364-4	2008	METHODS AND RESULTS: Basal and lipopolysaccharide-stimulated thioglycollate-elicited peritoneal macrophages showed increased inflammatory gene expression in the order Abca1(-/-)Abcg1(-/-)>Abcg1(-/-)>Abca1(-/-)>wild-type.	Thioglycolates	61-75	ATP-binding cassette, sub-family A (ABC1), member 1	Mus musculus	167-172
18941248-9	2008	Interestingly, application of CD97 mAbs blocked granulocyte trafficking after thioglycollate-induced peritonitis in wild-type but not in knock-out mice.	Thioglycolates	78-92	adhesion G protein-coupled receptor E5	Mus musculus	30-34
19015145-4	2009	Thioglycollate-elicited murine peritoneal macrophages were cultured with CLX-090717 and lipopolysaccharide (LPS)-induced TNF-alpha release was assayed.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	121-130
19020771-5	2008	Here we investigated the differential effects of apoptotic thymocytes (AoTC) on TNF-alpha release in immature thioglycolate-elicited PM (TGPM) and mature resident PM (RPM) in vitro by culturing them with or without AoTC and/or LPS.	Thioglycolates	110-123	tumor necrosis factor	Homo sapiens	80-89
18852364-4	2008	METHODS AND RESULTS: Basal and lipopolysaccharide-stimulated thioglycollate-elicited peritoneal macrophages showed increased inflammatory gene expression in the order Abca1(-/-)Abcg1(-/-)>Abcg1(-/-)>Abca1(-/-)>wild-type.	Thioglycolates	61-75	ATP binding cassette subfamily G member 1	Mus musculus	177-182
18852364-4	2008	METHODS AND RESULTS: Basal and lipopolysaccharide-stimulated thioglycollate-elicited peritoneal macrophages showed increased inflammatory gene expression in the order Abca1(-/-)Abcg1(-/-)>Abcg1(-/-)>Abca1(-/-)>wild-type.	Thioglycolates	61-75	ATP binding cassette subfamily G member 1	Mus musculus	191-196
18852364-4	2008	METHODS AND RESULTS: Basal and lipopolysaccharide-stimulated thioglycollate-elicited peritoneal macrophages showed increased inflammatory gene expression in the order Abca1(-/-)Abcg1(-/-)>Abcg1(-/-)>Abca1(-/-)>wild-type.	Thioglycolates	61-75	ATP-binding cassette, sub-family A (ABC1), member 1	Mus musculus	205-210
18852364-9	2008	To assess in vivo relevance, we injected intraperitoneally thioglycollate in Abcg1(-/-) bone marrow-transplanted, Western diet-fed, Ldlr-deficient mice.	Thioglycolates	59-73	ATP binding cassette subfamily G member 1	Mus musculus	77-82
17928531-2	2008	At 2 hours following an intraperitoneal injection of thioglycollate, there was a 4.5-fold increase in blood neutrophil numbers, which was inhibited 84% and 72% by prior administration of blocking mAbs against either the chemokines KC/MIP-2 or G-CSF, respectively.	Thioglycolates	53-67	chemokine (C-X-C motif) ligand 2	Mus musculus	234-239
18583455-6	2008	In a model of thioglycollate-induced inflammation, treating mice with CP-532,903 inhibited recruitment of leukocytes into the peritoneum by specifically activating the A(3)AR.	Thioglycolates	14-28	adenosine A3 receptor	Mus musculus	168-174
18606855-3	2008	We have confirmed the importance of this mechanism in a second model of thioglycollate-induced peritonitis and also show that PAR-1 is important for the production of MCP-3 and MCP-5.	Thioglycolates	72-86	coagulation factor II (thrombin) receptor	Rattus norvegicus	126-131
18519646-8	2008	In addition, extravasation of ST3Gal-IV(-/-) neutrophils into thioglycollate-pretreated peritoneal cavities was significantly decreased.	Thioglycolates	62-76	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	Homo sapiens	30-39
18414683-5	2008	In addition, thioglycollate-induced peritoneal leukocyte recruitment and accumulation were substantially reduced in Rock1(+/-) mice compared with those of WT and Rock2(+/-) mice.	Thioglycolates	13-27	Rho-associated coiled-coil containing protein kinase 1	Mus musculus	116-121
18303131-5	2008	That is, in NIH3T3 and MFG-E8(-/-) thioglycollate-elicited peritoneal macrophages that do not express MFG-E8, hMFG-E8 enhanced engulfment at low concentrations but inhibited it at high concentrations.	Thioglycolates	35-49	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	23-29
18303131-5	2008	That is, in NIH3T3 and MFG-E8(-/-) thioglycollate-elicited peritoneal macrophages that do not express MFG-E8, hMFG-E8 enhanced engulfment at low concentrations but inhibited it at high concentrations.	Thioglycolates	35-49	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	110-117
18303131-6	2008	On the other hand, hMFG-E8 dose-dependently inhibited the engulfment of apoptotic cells by MFG-E8(+/+) thioglycollate-elicited peritoneal macrophages, indicating that an excess of MFG-E8 has an inverse effect on the engulfment of apoptotic cells.	Thioglycolates	103-117	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	19-26
18303131-6	2008	On the other hand, hMFG-E8 dose-dependently inhibited the engulfment of apoptotic cells by MFG-E8(+/+) thioglycollate-elicited peritoneal macrophages, indicating that an excess of MFG-E8 has an inverse effect on the engulfment of apoptotic cells.	Thioglycolates	103-117	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	20-26
18303131-6	2008	On the other hand, hMFG-E8 dose-dependently inhibited the engulfment of apoptotic cells by MFG-E8(+/+) thioglycollate-elicited peritoneal macrophages, indicating that an excess of MFG-E8 has an inverse effect on the engulfment of apoptotic cells.	Thioglycolates	103-117	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	91-97
18628355-5	2008	Importantly, all of these effects were blunted by recombinant total adiponectin administration given 3 days prior to thioglycollate challenge.	Thioglycolates	117-131	adiponectin, C1Q and collagen domain containing	Mus musculus	68-79
18677407-6	2008	After induction of peritonitis by thioglycollate injection, we found that Plg(-/-) mice displayed diminished macrophage trans-ECM migration and decreased MMP-9 activation.	Thioglycolates	34-48	plasminogen	Mus musculus	74-77
18523137-5	2008	In thioglycollate-elicited macrophages, the production of inositol phosphate in response to UDP stimulation was lost, indicating that P2Y(6) is the unique UDP-responsive receptor expressed by mouse macrophages.	Thioglycolates	3-17	pyrimidinergic receptor P2Y, G-protein coupled, 6	Mus musculus	134-140
18239087-3	2008	Cbl-b-/- mice displayed increased macrophage recruitment in thioglycollate-induced peritonitis, which was attributed to Cbl-b deficiency in macrophages, as assessed by bone marrow chimera experiments.	Thioglycolates	60-74	Casitas B-lineage lymphoma b	Mus musculus	0-5
18239087-3	2008	Cbl-b-/- mice displayed increased macrophage recruitment in thioglycollate-induced peritonitis, which was attributed to Cbl-b deficiency in macrophages, as assessed by bone marrow chimera experiments.	Thioglycolates	60-74	Casitas B-lineage lymphoma b	Mus musculus	120-125
17928531-2	2008	At 2 hours following an intraperitoneal injection of thioglycollate, there was a 4.5-fold increase in blood neutrophil numbers, which was inhibited 84% and 72% by prior administration of blocking mAbs against either the chemokines KC/MIP-2 or G-CSF, respectively.	Thioglycolates	53-67	colony stimulating factor 3 (granulocyte)	Mus musculus	243-248
18514750-3	2008	We investigated the effect of substances capable of recruiting macrophages into the peritoneal cavity of mice (mineral oil and thioglycolate) on P2X7 receptor expression and function, addressing whether these stimuli can interfere with multinucleated giant cell (MGC) formation, ATP-induced apoptosis, plasma membrane permeabilization and nitric oxide production.	Thioglycolates	127-140	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	145-158
18354729-3	2008	In thioglycolate-elicited Mphis, methotrexate increased DPPIV (99-110%) and POP (60%), while cyclosporine inhibited POP (21%).	Thioglycolates	3-16	dipeptidylpeptidase 4	Mus musculus	56-61
18354729-3	2008	In thioglycolate-elicited Mphis, methotrexate increased DPPIV (99-110%) and POP (60%), while cyclosporine inhibited POP (21%).	Thioglycolates	3-16	prolyl endopeptidase	Mus musculus	76-79
18354729-3	2008	In thioglycolate-elicited Mphis, methotrexate increased DPPIV (99-110%) and POP (60%), while cyclosporine inhibited POP (21%).	Thioglycolates	3-16	prolyl endopeptidase	Mus musculus	116-119
18223298-5	2008	(2) Thioglycollate-elicited mouse peritoneal macrophages were stimulated by Pseudomonas lipopolysaccharides (LPS) in the presence of graded concentrations of fluoroquinolones, and macrophage-derived tumor necrosis factor alpha (TNF-alpha) was assessed.	Thioglycolates	4-18	tumor necrosis factor	Mus musculus	199-226
18223298-5	2008	(2) Thioglycollate-elicited mouse peritoneal macrophages were stimulated by Pseudomonas lipopolysaccharides (LPS) in the presence of graded concentrations of fluoroquinolones, and macrophage-derived tumor necrosis factor alpha (TNF-alpha) was assessed.	Thioglycolates	4-18	tumor necrosis factor	Mus musculus	228-237
17996695-5	2007	When thioglycollate-elicited macrophages pre-exposed to prodigiosin (1-100 ng/ml) were stimulated with LPS, pretreatment with prodigiosin resulted in the inhibition of NO production and inducible nitric oxide synthase (iNOS) protein and mRNA expression in a concentration-dependent manner.	Thioglycolates	5-19	nitric oxide synthase 2, inducible	Mus musculus	186-217
17996695-5	2007	When thioglycollate-elicited macrophages pre-exposed to prodigiosin (1-100 ng/ml) were stimulated with LPS, pretreatment with prodigiosin resulted in the inhibition of NO production and inducible nitric oxide synthase (iNOS) protein and mRNA expression in a concentration-dependent manner.	Thioglycolates	5-19	nitric oxide synthase 2, inducible	Mus musculus	219-223
17690254-5	2007	All 4 Plg-Rs were present on the surface of these cells and showed enhanced expression on the thioglycollate-induced macrophages compared with peripheral blood monocytes.	Thioglycolates	94-108	plasminogen	Mus musculus	6-9
29350811-4	2007	Initially, there was increased cell survival, but death eventually occurred by necrosis within 48 h. Neutrophils persisted in thioglycollate-induced inflammation in Gulo-/R mice with the later appearance of necrotic cells, suggesting that apoptosis was also affected in vivo.	Thioglycolates	126-140	gulonolactone (L-) oxidase	Mus musculus	165-169
17699741-7	2007	In thioglycollate-induced peritonitis and lipopolysaccaride (LPS)-induced lung inflammation, chimeric mice lacking Galpha(i2) in hematopoietic cells showed about 50% reduced neutrophil recruitment similar to that seen in Gnai2(-/-) mice.	Thioglycolates	3-17	guanine nucleotide binding protein (G protein), alpha inhibiting 2	Mus musculus	115-124
17543554-7	2007	Neutrophil recruitment in a thioglycollate-induced peritonitis model was almost completely inhibited in Selplg(-/-) mice or Syk(-/-) bone-marrow chimeras treated with pertussis toxin.	Thioglycolates	28-42	spleen tyrosine kinase	Mus musculus	124-127
17626151-8	2007	In vivo thioglycollate-elicited Mvarphi also exhibited increased phagocytic ability upon IFN-gamma activation and hCG treatment.	Thioglycolates	8-22	interferon gamma	Homo sapiens	89-98
17626151-8	2007	In vivo thioglycollate-elicited Mvarphi also exhibited increased phagocytic ability upon IFN-gamma activation and hCG treatment.	Thioglycolates	8-22	chorionic gonadotropin subunit beta 5	Homo sapiens	114-117
17342418-0	2007	LPS suppresses expression of asialoglycoprotein-binding protein through TLR4 in thioglycolate-elicited peritoneal macrophages.	Thioglycolates	80-93	toll-like receptor 4	Mus musculus	72-76
17342418-3	2007	We found here that LPS is able to down-regulate the mRNA expression of M-ASGP-BP in a time-dependent manner using thioglycolate-elicited rat and mouse peritoneal macrophages.	Thioglycolates	114-127	C-type lectin domain containing 10A	Rattus norvegicus	71-80
17475886-8	2007	DBA mice, which have an inactivating point mutation in the gpnmb gene, exhibited reduced numbers of myeloid cells, elevated numbers of thioglycolate-elicited peritoneal macrophages, and higher levels of proinflammatory cytokines in response to LPS.	Thioglycolates	135-148	glycoprotein (transmembrane) nmb	Mus musculus	59-64
17264304-4	2007	Initially, there was increased cell survival, but death eventually occurred by necrosis within 48 h. Neutrophils persisted in thioglycollate-induced inflammation in Gulo-/- mice with the later appearance of necrotic cells, suggesting that apoptosis was also affected in vivo.	Thioglycolates	126-140	gulonolactone (L-) oxidase	Mus musculus	165-169
18274640-12	2007	PDE4 inhibitors also inhibited lipopolysaccharide-induced TNF-alpha and IL-12 production from thioglycolate-induced murine peritoneal macrophages and the proliferation of rat synovial fibroblasts.	Thioglycolates	94-107	tumor necrosis factor	Mus musculus	58-67
17372166-6	2007	Furthermore, mice deficient in CD40L show significantly reduced thioglycolate-elicited invasion of inflammatory cells into the peritoneal cavity compared with mice deficient in CD40 and wild-type controls.	Thioglycolates	64-77	CD40 ligand	Mus musculus	31-36
17372166-6	2007	Furthermore, mice deficient in CD40L show significantly reduced thioglycolate-elicited invasion of inflammatory cells into the peritoneal cavity compared with mice deficient in CD40 and wild-type controls.	Thioglycolates	64-77	CD40 antigen	Mus musculus	31-35
16849643-3	2006	We report that the P1-ablated mouse, Siat1DeltaP1, and a globally ST6Gal-1-deficient mouse had significantly increased peritoneal leukocytosis after intraperitoneal challenge with thioglycollate.	Thioglycolates	180-194	beta galactoside alpha 2,6 sialyltransferase 1	Mus musculus	66-74
17237600-4	2007	We have previously shown that fibronectin-bound S. aureus is efficiently phagocytosed by thioglycolate-induced mouse peritoneal macrophages.	Thioglycolates	89-102	fibronectin 1	Mus musculus	30-41
16470243-4	2006	In contrast to the embryonic-lethal phenotype of alpha4 integrin-null mice, mice bearing the alpha4(Y991A) mutation were viable and fertile; however, they exhibited defective recruitment of mononuclear leukocytes into thioglycollate-induced peritonitis.	Thioglycolates	218-232	immunoglobulin (CD79A) binding protein 1	Mus musculus	93-99
16818777-6	2006	In line, tPA(-/-) mice demonstrated a reduced thioglycolate-induced neutrophil influx into the peritoneal cavity and i.p.	Thioglycolates	46-59	plasminogen activator, tissue	Mus musculus	9-12
16601837-6	2006	The reduced macrophage numbers in the peritoneal cavities of t-PA-/- mice could be increased by administration of plasmin or t-PA prior to harvesting the thioglycolate-elicited exudates.	Thioglycolates	154-167	plasminogen activator, tissue	Mus musculus	61-65
16601837-6	2006	The reduced macrophage numbers in the peritoneal cavities of t-PA-/- mice could be increased by administration of plasmin or t-PA prior to harvesting the thioglycolate-elicited exudates.	Thioglycolates	154-167	plasminogen activator, tissue	Mus musculus	125-129
16872643-2	2006	To test the hypothesis that this inhibition of feeding is due to a substrate-driven increase in hepatic fatty acid oxidation (FAO), we assessed the ability of the FAO inhibitor mercaptoacetate (MA) to reverse the feeding-inhibitory effect of the beta3-AR agonist CGP 12177A (CGP).	Thioglycolates	177-192	adrenoceptor beta 3	Rattus norvegicus	246-254
16877523-6	2006	In thioglycollate-elicited peritoneal macrophages (TEPM), which survive in the absence of exogenous CSF-1, CYC10268 impaired LPS-induced cytokine production and regulated expression of known CSF-1 target genes.	Thioglycolates	3-17	colony stimulating factor 1 (macrophage)	Mus musculus	191-196
16205123-5	2005	Utilizing in vitro phagocytosis assays of both apoptotic thymocytes and Escherichia coli K-12 BioParticles, we demonstrate that the loss of Cav-1 decreases the phagocytic ability of thioglycollate-elicited peritoneal macrophages.	Thioglycolates	182-196	caveolin 1, caveolae protein	Mus musculus	140-145
16339540-2	2005	Ligation of MARCO on mouse thioglycollate-elicited peritoneal macrophages (PEMs) with immobilized mAb costimulated IL-12 production, in contrast to previously reported inhibition by SR-AI/II.	Thioglycolates	27-41	macrophage receptor with collagenous structure	Mus musculus	12-17
16339540-2	2005	Ligation of MARCO on mouse thioglycollate-elicited peritoneal macrophages (PEMs) with immobilized mAb costimulated IL-12 production, in contrast to previously reported inhibition by SR-AI/II.	Thioglycolates	27-41	macrophage scavenger receptor 1	Mus musculus	182-187
16186163-2	2005	Using an in vitro model of macrophage activation, we show that schistosome larvae possess molecules that directly stimulate both thioglycollate-elicited macrophages (tM) and IFNgamma-activated tM in vitro to produce several cytokines including IL-6, IL-12p40 and IL-10.	Thioglycolates	129-143	interleukin 6	Mus musculus	244-248
16186163-2	2005	Using an in vitro model of macrophage activation, we show that schistosome larvae possess molecules that directly stimulate both thioglycollate-elicited macrophages (tM) and IFNgamma-activated tM in vitro to produce several cytokines including IL-6, IL-12p40 and IL-10.	Thioglycolates	129-143	interleukin 12b	Mus musculus	250-258
16186163-2	2005	Using an in vitro model of macrophage activation, we show that schistosome larvae possess molecules that directly stimulate both thioglycollate-elicited macrophages (tM) and IFNgamma-activated tM in vitro to produce several cytokines including IL-6, IL-12p40 and IL-10.	Thioglycolates	129-143	interleukin 10	Mus musculus	263-268
16249345-7	2005	After oral administration, GW2580 blocked the ability of exogenous CSF-1 to increase LPS-induced IL-6 production in mice, inhibited the growth of CSF-1-dependent M-NFS-60 tumor cells in the peritoneal cavity, and diminished the accumulation of macrophages in the peritoneal cavity after thioglycolate injection.	Thioglycolates	287-300	colony stimulating factor 1 (macrophage)	Mus musculus	67-72
16130044-6	2005	At the minimum concentration of thioglycolate required to elute S100A3 protein from the endocuticle into the reductive permanent waving lotion, enlarged delaminated cuticle fragments were observed.	Thioglycolates	32-45	S100 calcium binding protein A3	Homo sapiens	64-70
16085208-4	2005	Moreover, both myotoxins induced the release of H(2)O(2) by thioglycollate-elicited macrophages, MT-III being the most potent stimulator.	Thioglycolates	60-74	metallothionein 3	Mus musculus	97-103
15895074-2	2005	Here we show that such inflammation requires the forkhead transcription factor Foxo3a: Foxo3a-deficient mice are resistant to two models of neutrophilic inflammation, immune complex-mediated inflammatory arthritis and thioglycollate-induced peritonitis.	Thioglycolates	218-232	forkhead box O3	Mus musculus	79-85
15895074-2	2005	Here we show that such inflammation requires the forkhead transcription factor Foxo3a: Foxo3a-deficient mice are resistant to two models of neutrophilic inflammation, immune complex-mediated inflammatory arthritis and thioglycollate-induced peritonitis.	Thioglycolates	218-232	forkhead box O3	Mus musculus	87-93
15748244-9	2005	Finally, we showed that fondaparinux reduced thioglycollate-induced recruitment of neutrophils into the peritoneum and inhibited the binding of U937 cells to P-selectin in vitro.	Thioglycolates	45-59	selectin P	Homo sapiens	158-168
15640397-9	2005	In addition, levels of CD80 and CD86 on human monocytic THP-1 cells were decreased in a dose-dependent manner in the presence of 0.1 to 10 microM DZ2002, and decreases were also seen in IL-12 and tumor necrosis factor-alpha production from both mouse thioglycollate-stimulated peritoneal macrophages and THP-1 cells.	Thioglycolates	251-265	CD80 molecule	Homo sapiens	23-27
15640397-9	2005	In addition, levels of CD80 and CD86 on human monocytic THP-1 cells were decreased in a dose-dependent manner in the presence of 0.1 to 10 microM DZ2002, and decreases were also seen in IL-12 and tumor necrosis factor-alpha production from both mouse thioglycollate-stimulated peritoneal macrophages and THP-1 cells.	Thioglycolates	251-265	CD86 molecule	Homo sapiens	32-36
15824084-6	2005	CD44 enables slow leukocyte rolling on E-selectin expressed on inflamed endothelium in vivo and cooperates with P-selectin glycoprotein ligand-1 to recruit neutrophils into thioglycollate-induced peritonitis and staphylococcal enterotoxin A-injected skin pouch.	Thioglycolates	173-187	CD44 molecule (Indian blood group)	Homo sapiens	0-4
15824084-6	2005	CD44 enables slow leukocyte rolling on E-selectin expressed on inflamed endothelium in vivo and cooperates with P-selectin glycoprotein ligand-1 to recruit neutrophils into thioglycollate-induced peritonitis and staphylococcal enterotoxin A-injected skin pouch.	Thioglycolates	173-187	selectin P ligand	Homo sapiens	112-144
15743787-8	2005	Recombinant human HMGB1/amphoterin induced growth inhibition in thioglycollate-induced rat peritoneal macrophages, PMA-U937 cells, and human alveolar macrophages, an effect that was abrogated by absorption with anti-HMGB1 antibody.	Thioglycolates	64-78	high mobility group box 1	Homo sapiens	18-23
15743787-8	2005	Recombinant human HMGB1/amphoterin induced growth inhibition in thioglycollate-induced rat peritoneal macrophages, PMA-U937 cells, and human alveolar macrophages, an effect that was abrogated by absorption with anti-HMGB1 antibody.	Thioglycolates	64-78	high mobility group box 1	Homo sapiens	24-34
15743787-8	2005	Recombinant human HMGB1/amphoterin induced growth inhibition in thioglycollate-induced rat peritoneal macrophages, PMA-U937 cells, and human alveolar macrophages, an effect that was abrogated by absorption with anti-HMGB1 antibody.	Thioglycolates	64-78	high mobility group box 1	Homo sapiens	216-221
15722356-3	2005	Thioglycollate-elicited macrophages isolated from mPGES-1-/- animals and genetically matched wild type controls were stimulated with diverse pro-inflammatory stimuli.	Thioglycolates	0-14	prostaglandin E synthase	Mus musculus	50-57
15807994-6	2005	The role of resident cells on the PAL effect was evaluated using three strategies: reducing the total resident cell population by lavage of rat cavities with saline; increasing macrophage population by treating animals with thioglycolate; and depleting mast cell population by subchronic treatment of rats with compound 48/80.	Thioglycolates	224-237	leucine-rich repeat, Ig-like and transmembrane domains 1	Rattus norvegicus	34-37
15807994-10	2005	The neutrophil stimulatory effect of PAL was potentiated in animals treated with both thioglycolate and compound 48/ 80.	Thioglycolates	86-99	leucine-rich repeat, Ig-like and transmembrane domains 1	Rattus norvegicus	37-40
15794588-3	2005	DES, BPA, EHP and NP stimulated thioglycolate-induced peritoneal exudate cells (macrophages) to produce cytokines such as interleukin (IL)-1, IL-6, IL-12, tumor necrosis factor and macrophage chemotactic protein- 1.	Thioglycolates	32-45	interleukin 6	Mus musculus	142-146
15544923-4	2004	PON2 expression was analyzed in vitro in THP-1 cells differentiated with 1alpha,25-dihydroxyvitamin D3 and in vivo in mouse peritoneal macrophages (MPM) isolated at increasing time intervals after intraperitoneal thioglycollate injection.	Thioglycolates	213-227	paraoxonase 2	Homo sapiens	0-4
15485832-6	2004	In vivo, inhibition of JAM-C with soluble mouse JAM-C resulted in a 50% reduction of neutrophil emigration in the mouse model of acute thioglycollate-induced peritonitis.	Thioglycolates	135-149	junction adhesion molecule 3	Mus musculus	23-28
15485832-6	2004	In vivo, inhibition of JAM-C with soluble mouse JAM-C resulted in a 50% reduction of neutrophil emigration in the mouse model of acute thioglycollate-induced peritonitis.	Thioglycolates	135-149	junction adhesion molecule 3	Mus musculus	48-53
15316030-7	2004	Ligation of SR-A also inhibited lipopolysaccharide plus interferon-gamma-stimulated interleukin-12 (IL-12) release, by 25% in AMs and by 68% in thioglycollate-elicited PMs, consistent with different levels of SR-A expression.	Thioglycolates	144-158	macrophage scavenger receptor 1	Mus musculus	12-16
15585886-8	2004	Additionally, after stimulation with thioglycolate, lpr/lpr and B6 mice showed equivalent numbers of peritoneal macrophages.	Thioglycolates	37-50	Fas (TNF receptor superfamily member 6)	Mus musculus	52-55
15585886-8	2004	Additionally, after stimulation with thioglycolate, lpr/lpr and B6 mice showed equivalent numbers of peritoneal macrophages.	Thioglycolates	37-50	Fas (TNF receptor superfamily member 6)	Mus musculus	56-59
15770051-2	2004	Intraperitoneal injection of thioglycollate increased peritoneal CCL6, which peaked at 4 h and remained elevated at 48 h. Neutralization of CCL6 significantly inhibited the macrophage infiltration (34-48% reduction), but not other cell types, without decreasing the other CC chemokines known to attract monocytes/macrophages.	Thioglycolates	29-43	chemokine (C-C motif) ligand 6	Mus musculus	65-69
15770051-2	2004	Intraperitoneal injection of thioglycollate increased peritoneal CCL6, which peaked at 4 h and remained elevated at 48 h. Neutralization of CCL6 significantly inhibited the macrophage infiltration (34-48% reduction), but not other cell types, without decreasing the other CC chemokines known to attract monocytes/macrophages.	Thioglycolates	29-43	chemokine (C-C motif) ligand 6	Mus musculus	140-144
15316030-7	2004	Ligation of SR-A also inhibited lipopolysaccharide plus interferon-gamma-stimulated interleukin-12 (IL-12) release, by 25% in AMs and by 68% in thioglycollate-elicited PMs, consistent with different levels of SR-A expression.	Thioglycolates	144-158	interferon gamma	Mus musculus	56-72
15626158-2	2004	Thioglycollate-elicited neutrophils from BALB/c mice failed to respond to vCXCL-1 while retaining the capacity to respond to known murine (Mu) CXCR2 ligands, such as hCXCL8 (IL8) and mCXCL1 (KC).	Thioglycolates	0-14	chemokine (C-X-C motif) receptor 2	Mus musculus	143-148
15113755-7	2004	Thioglycolate-elicited macrophages pulsed with oxidized low-density lipoproteins expressed enhanced CD1d levels and induced NKT cells to produce interferon-gamma, a potentially proatherogenic T-helper 1 (TH1) cytokine.	Thioglycolates	0-13	CD1d1 antigen	Mus musculus	100-104
15113755-7	2004	Thioglycolate-elicited macrophages pulsed with oxidized low-density lipoproteins expressed enhanced CD1d levels and induced NKT cells to produce interferon-gamma, a potentially proatherogenic T-helper 1 (TH1) cytokine.	Thioglycolates	0-13	interferon gamma	Mus musculus	145-161
15626158-2	2004	Thioglycollate-elicited neutrophils from BALB/c mice failed to respond to vCXCL-1 while retaining the capacity to respond to known murine (Mu) CXCR2 ligands, such as hCXCL8 (IL8) and mCXCL1 (KC).	Thioglycolates	0-14	C-X-C motif chemokine ligand 8	Homo sapiens	166-172
15626158-2	2004	Thioglycollate-elicited neutrophils from BALB/c mice failed to respond to vCXCL-1 while retaining the capacity to respond to known murine (Mu) CXCR2 ligands, such as hCXCL8 (IL8) and mCXCL1 (KC).	Thioglycolates	0-14	chemokine (C-X-C motif) ligand 15	Mus musculus	174-177
15626158-2	2004	Thioglycollate-elicited neutrophils from BALB/c mice failed to respond to vCXCL-1 while retaining the capacity to respond to known murine (Mu) CXCR2 ligands, such as hCXCL8 (IL8) and mCXCL1 (KC).	Thioglycolates	0-14	chemokine (C-X-C motif) ligand 1	Mus musculus	183-189
14764668-3	2004	Macrophages were prepared from peritoneal fluid of thioglycolate-treated mice carrying either a wild-type or a disrupted TLR4-encoding gene and were examined for their ability to phagocytose apoptotic mouse thymocytes, apoptotic Jurkat T cells, Ig-opsonized mouse thymocytes, Ig-opsonized zymosan particles, and latex beads.	Thioglycolates	51-64	toll-like receptor 4	Mus musculus	121-125
15251190-4	2004	Peritoneal thioglycollate-exudated macrophages (PEMs) that were induced to die by combined treatment with LPS and cycloheximide (protein synthesis inhibitor) were killed by the treatment with SOD and catalase in the presence of cycloheximide.	Thioglycolates	11-25	catalase	Mus musculus	200-208
15240719-2	2004	Freshly isolated peritoneal macrophages elicited in vivo with thioglycolate (TG) from A/J mice are highly permissive to L. pneumophila growth in vitro, while TG-elicited macrophages from CD1 mice are resistant.	Thioglycolates	77-79	CD1 antigen complex	Mus musculus	187-190
15240719-2	2004	Freshly isolated peritoneal macrophages elicited in vivo with thioglycolate (TG) from A/J mice are highly permissive to L. pneumophila growth in vitro, while TG-elicited macrophages from CD1 mice are resistant.	Thioglycolates	158-160	CD1 antigen complex	Mus musculus	187-190
15153528-5	2004	Peptides that bound to the alpha(M) integrin-I domain and inhibited its complex formation with proMMP-9 prevented neutrophil migration in a transendothelial assay in vitro and in a thioglycolate-elicited peritonitis in vivo.	Thioglycolates	181-194	matrix metallopeptidase 9	Mus musculus	95-103
15048712-4	2004	with adherent thioglycolate-elicited peritoneal exudate cells cultured with TGF beta(2) and antigen (TGF beta-treated APC) transferred tolerance to naive recipients.	Thioglycolates	14-27	transforming growth factor, beta 1	Mus musculus	76-84
15048712-4	2004	with adherent thioglycolate-elicited peritoneal exudate cells cultured with TGF beta(2) and antigen (TGF beta-treated APC) transferred tolerance to naive recipients.	Thioglycolates	14-27	transforming growth factor, beta 1	Mus musculus	101-109
15004139-5	2004	Thioglycolate-elicited peritoneal macrophages deficient in CD93 showed a similar enhancement in complement- and FcgammaR-dependent uptake of RBC to the wild-type macrophages when plated on C1q-coated surfaces suggesting that the lack of this receptor had no effect on these C1q-mediated events.	Thioglycolates	0-13	CD93 antigen	Mus musculus	59-63
15004139-5	2004	Thioglycolate-elicited peritoneal macrophages deficient in CD93 showed a similar enhancement in complement- and FcgammaR-dependent uptake of RBC to the wild-type macrophages when plated on C1q-coated surfaces suggesting that the lack of this receptor had no effect on these C1q-mediated events.	Thioglycolates	0-13	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	189-192
15004139-5	2004	Thioglycolate-elicited peritoneal macrophages deficient in CD93 showed a similar enhancement in complement- and FcgammaR-dependent uptake of RBC to the wild-type macrophages when plated on C1q-coated surfaces suggesting that the lack of this receptor had no effect on these C1q-mediated events.	Thioglycolates	0-13	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	274-277
15004139-10	2004	Thus, our findings indicate that murine CD93 is expressed on the peritoneal macrophage, especially on thioglycolate-elicited cells, but does not appear to play a key role in C1q-mediated enhancement of phagocytosis or in the intercellular adhesion events tested.	Thioglycolates	102-115	CD93 antigen	Mus musculus	40-44
15457471-9	2004	In support of the antiinflammatory effect of Tnfip6 via the inhibition of polymorphonuclear (PMN) cell efflux, neutrophil invasion during thioglycollate-induced peritonitis was 2-fold higher in Tnfip6-deficient animals than in wild-type animals, but was dramatically suppressed by intravenous injection of recombinant murine Tnfip6.	Thioglycolates	138-152	tumor necrosis factor alpha induced protein 6	Mus musculus	45-51
15302904-4	2004	Here, we report that an MFG-E8 mutant, designated as D89E, carrying a point mutation in an RGD motif, inhibited not only the phagocytosis of apoptotic cells by a wide variety of phagocytes, but also inhibited the enhanced production of IL-10 by thioglycollate-elicited peritoneal macrophages phagocytosing apoptotic cells.	Thioglycolates	245-259	milk fat globule EGF and factor V/VIII domain containing	Mus musculus	24-30
15039391-6	2004	We also demonstrated that IgA, in synergy with IFN-gamma, induced TNF-alpha production and apoptosis of thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	104-118	interferon gamma	Mus musculus	47-56
14597759-6	2003	In response to intraperitoneal thioglycollate, recruitment of leukocytes in OPN-/- mice was impaired, and OPN-/- leukocytes exhibited decreased basal and MCP-1-directed migration.	Thioglycolates	31-45	secreted phosphoprotein 1	Mus musculus	76-79
14504107-9	2004	Thioglycolate-elicited peritoneal macrophages, furthermore, displayed an additional 3.8-fold increase in annexin II surface expression compared with resident cells.	Thioglycolates	0-13	annexin A2	Homo sapiens	105-115
15051510-5	2004	Thioglycollate-elicited peritoneal exudate cells (PEC) were stimulated in vitro with interferon-gamma and lipopolysaccharide.	Thioglycolates	0-14	interferon gamma	Mus musculus	85-101
12619907-3	2003	In the present experiments, the authors assessed the role of the dopamine-3 receptor (D3R) in the feeding responses to 2-deoxy-D-glucose, mercaptoacetate, and peripheral insulin.	Thioglycolates	138-153	dopamine receptor D3	Mus musculus	65-84
12917471-3	2003	We found that HSV-2 infection of thioglycolate-activated PCs from BALB/c mice rapidly led to expression of type 1 IFNs (IFN-alpha/beta) and interleukin (IL)-12, which was followed by production of IFN-gamma.	Thioglycolates	33-46	interferon alpha	Mus musculus	120-129
12917471-3	2003	We found that HSV-2 infection of thioglycolate-activated PCs from BALB/c mice rapidly led to expression of type 1 IFNs (IFN-alpha/beta) and interleukin (IL)-12, which was followed by production of IFN-gamma.	Thioglycolates	33-46	interferon gamma	Mus musculus	197-206
12821115-5	2003	Although thioglycolate-elicited murine peritoneal macrophages did not express a detectable level of TWEAK on their surface, they secreted functional TWEAK that was cytotoxic against mFn14/L5178Y cells and neutralized by MTW-1.	Thioglycolates	9-22	tumor necrosis factor (ligand) superfamily, member 12	Mus musculus	149-154
12821115-5	2003	Although thioglycolate-elicited murine peritoneal macrophages did not express a detectable level of TWEAK on their surface, they secreted functional TWEAK that was cytotoxic against mFn14/L5178Y cells and neutralized by MTW-1.	Thioglycolates	9-22	tumor necrosis factor receptor superfamily, member 12a	Mus musculus	182-187
12623845-6	2003	Endogenous peritoneal macrophages and mesothelial cells lining the peritoneum contain MCP-1, which is released following thioglycollate stimulation.	Thioglycolates	121-135	chemokine (C-C motif) ligand 2	Mus musculus	86-91
12714575-3	2003	In BioGel- and thioglycollate-elicited M(phi), interleukin (IL)-4 up-regulated total cell-associated MR (cMR), correlating with enhanced surface expression.	Thioglycolates	15-29	interleukin 4	Mus musculus	47-65
14615411-8	2003	Additional immunoblot and RT-PCR experiments showed that the ACAT2 signal was clearly detectable in thioglycollate-elicited exudate mouse macrophages but not in peritoneal resident macrophages.	Thioglycolates	100-114	acetyl-Coenzyme A acetyltransferase 2	Mus musculus	61-66
12777465-3	2003	Here we show that treatment of thioglycollate-elicited mouse peritoneal macrophages with various unrelated apoptotic agents, including simvastatin, camptothecin, or glucose deprivation, is associated with a specific and large increase in caveolin-1 expression.	Thioglycolates	31-45	caveolin 1, caveolae protein	Mus musculus	238-248
12619907-3	2003	In the present experiments, the authors assessed the role of the dopamine-3 receptor (D3R) in the feeding responses to 2-deoxy-D-glucose, mercaptoacetate, and peripheral insulin.	Thioglycolates	138-153	dopamine receptor D3	Mus musculus	86-89
12504109-5	2003	CE hydrolysis was also significantly reduced in thioglycollate elicited peritoneal exudate cells of CCR2(-/-) mice, related to paucity of macrophages in the cell differential.	Thioglycolates	48-62	chemokine (C-C motif) receptor 2	Mus musculus	100-104
12101261-2	2002	In this study, we investigated the capacity of in vivo acute and chronic morphine treatment to modulate interleukin (IL)-10 and IL-12 production by LPS and interferon-gamma-stimulated resident and thioglycollate-elicited murine peritoneal macrophages and the development of tolerance to these effects.	Thioglycolates	197-211	interferon gamma	Mus musculus	156-172
14621961-1	2003	The effect of thioglycolate-based depilatory lotions was studied on the in vitro passive and iontophoretic permeability of insulin through porcine epidermis and biophysical changes in the stratum corneum (SC) lipids and proteins.	Thioglycolates	14-27	insulin	Homo sapiens	123-130
12546135-4	2002	The effect of morphine was time-dependent, with significant effects first apparent at 4 hr after TG, but the administration of morphine 1 hr before or simultaneously with TG produced a similar increase in CD11b/c(+)HIS48med granulocytes.	Thioglycolates	171-173	integrin subunit alpha M	Rattus norvegicus	205-210
12417566-7	2002	In a thioglycollate model of peritoneal inflammation, leukocyte migration at 72 hours increased significantly in Plg(+/-)/pCPB(+/-) and Plg(+/-)/pCPB(-/-) compared with their wild-type counterparts.	Thioglycolates	5-19	plasminogen	Mus musculus	113-116
12417566-7	2002	In a thioglycollate model of peritoneal inflammation, leukocyte migration at 72 hours increased significantly in Plg(+/-)/pCPB(+/-) and Plg(+/-)/pCPB(-/-) compared with their wild-type counterparts.	Thioglycolates	5-19	plasminogen	Mus musculus	136-139
12016228-8	2002	The mMGL2 mRNA was also detected in mMGL1-positive cells, which were sorted from thioglycollate-induced peritoneal cells with a mMGL1-specific monoclonal antibody, LOM-8.7.	Thioglycolates	81-95	macrophage galactose N-acetyl-galactosamine specific lectin 2	Mus musculus	4-9
11982590-2	2002	BCG stimulated thioglycollate-elicited murine peritoneal exudate cells (PEC) to induce cytotoxic activity and to produce cytokines such as interferon (IFN)-gamma, tumour necrosis factor (TNF)-alpha and PGE2.	Thioglycolates	15-29	interferon gamma	Mus musculus	139-161
12000961-4	2002	We found that milk fat globule-EGF-factor 8 (MFG-E8), a secreted glycoprotein, was produced by thioglycollate-elicited macrophages.	Thioglycolates	95-109	milk fat globule EGF and factor V/VIII domain containing	Mus musculus	14-43
12000961-4	2002	We found that milk fat globule-EGF-factor 8 (MFG-E8), a secreted glycoprotein, was produced by thioglycollate-elicited macrophages.	Thioglycolates	95-109	milk fat globule EGF and factor V/VIII domain containing	Mus musculus	45-51
12023293-6	2002	The expression of mEMR4 is up-regulated following macrophage activation in Biogel and thioglycollate-elicited peritoneal macrophages.	Thioglycolates	86-100	adhesion G protein-coupled receptor E4	Mus musculus	18-23
11982590-2	2002	BCG stimulated thioglycollate-elicited murine peritoneal exudate cells (PEC) to induce cytotoxic activity and to produce cytokines such as interferon (IFN)-gamma, tumour necrosis factor (TNF)-alpha and PGE2.	Thioglycolates	15-29	tumor necrosis factor	Mus musculus	163-197
11926992-2	2002	The treatment of fibronectin-unstimulated and stimulated mouse thioglycolate-induced macrophages with inhibitors of myosin light chain kinase, protein kinase C and protein tyrosine kinase resulted in decreased macrophage binding of oxLDL, macrophage foam cell formation, and whole intracellular protein phosphorylation.	Thioglycolates	63-76	fibronectin 1	Mus musculus	17-28
11927655-2	2002	Here, we elucidated this anti-inflammatory activity further by investigating whether PPAR-gamma ligands regulated a panel of proinflammatory and anti-inflammatory cytokines produced by primary inflammatory murine Mphi (thioglycollate-elicited peritoneal exudate Mphi; PEM).	Thioglycolates	219-233	peroxisome proliferator activated receptor gamma	Mus musculus	85-95
11796582-10	2002	In vitro experiments using either resident or thioglycolate-elicited peritoneal macrophages showed a significant increase in the number of bacteria inside C1q-deficient macrophages compared to controls irrespective of the serum used for opsonizing the bacteria.	Thioglycolates	46-59	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	155-158
11751985-7	2002	Expression of Toll-like receptor (TLR)9, which is necessary for responses to CpG DNA, was markedly suppressed by CSF-1 in both BMMs and thioglycolate-elicited peritoneal macrophages.	Thioglycolates	136-149	toll-like receptor 9	Mus musculus	34-39
11751985-7	2002	Expression of Toll-like receptor (TLR)9, which is necessary for responses to CpG DNA, was markedly suppressed by CSF-1 in both BMMs and thioglycolate-elicited peritoneal macrophages.	Thioglycolates	136-149	colony stimulating factor 1 (macrophage)	Mus musculus	113-118
11867678-6	2002	p47(phox-/-) mice generated more thioglycollate-elicited peritoneal leukocytosis than wild-type mice.	Thioglycolates	33-47	NSFL1 (p97) cofactor (p47)	Mus musculus	0-3
11867678-9	2002	These data suggest that LTB(4) and C5a have separate but overlapping roles in thioglycollate-elicited peritonitis, and at least the leukotriene component is, in turn, regulated by reactive oxidants.	Thioglycolates	78-92	hemolytic complement	Mus musculus	35-38
11777984-4	2002	Initial studies revealed a marked defect in the ability of these DBP(-/-) mice to recruit cells to the peritoneum after localized thioglycolate injection.	Thioglycolates	130-143	D site albumin promoter binding protein	Mus musculus	65-68
11789671-3	2002	The CB2 was undetectable in resident peritoneal macrophages, present at high levels in thioglycolate-elicited inflammatory and interferon gamma (IFNgamma)-primed peritoneal macrophages, and detected at significantly diminished levels in bacterial lipopolysaccharide (LPS)-activated peritoneal macrophages.	Thioglycolates	87-100	cannabinoid receptor 2 (macrophage)	Mus musculus	4-7
11789671-3	2002	The CB2 was undetectable in resident peritoneal macrophages, present at high levels in thioglycolate-elicited inflammatory and interferon gamma (IFNgamma)-primed peritoneal macrophages, and detected at significantly diminished levels in bacterial lipopolysaccharide (LPS)-activated peritoneal macrophages.	Thioglycolates	87-100	interferon gamma	Mus musculus	127-155
12112010-3	2002	Moreover, p38 inhibition upregulates JNK and ERK activity in M1 cells and in thioglycollate-elicited peritoneal exudate macrophages.	Thioglycolates	77-91	mitogen-activated protein kinase 14	Mus musculus	10-13
11831442-11	2001	In conclusion, CLP is a more potent stimulus for apoptosis of leukocytes than their migration to the site of inflammation alone, as occurs in the thioglycollate model.	Thioglycolates	146-160	hyaluronan and proteoglycan link protein 1	Mus musculus	15-18
11380699-3	2001	Following co-incubation of either bone marrow-derived macrophages (Mphi) or thioglycollate-elicited peritoneal Mphi from CD14-/- mice with viable M. avium, tumour necrosis factor (TNF) production was significantly reduced and delayed compared to TNF secretion by infected CD14+/+ Mphi.	Thioglycolates	76-90	CD14 antigen	Mus musculus	121-125
11549608-8	2001	We measured KC and MIP-2 in the peritoneum after thioglycollate injection and demonstrated that IL-8-positive mice have significantly higher levels of the chemokines compared to the IL-8-negative mice.	Thioglycolates	49-63	chemokine (C-X-C motif) ligand 15	Mus musculus	96-100
11549608-9	2001	Antibody inhibition of KC and MIP-2 in the IL-8-positive mice significantly decreased peritoneal neutrophil recruitment in response to thioglycollate, clarifying their important role in the local neutrophil recruitment.	Thioglycolates	135-149	chemokine (C-X-C motif) ligand 2	Mus musculus	30-35
11549608-9	2001	Antibody inhibition of KC and MIP-2 in the IL-8-positive mice significantly decreased peritoneal neutrophil recruitment in response to thioglycollate, clarifying their important role in the local neutrophil recruitment.	Thioglycolates	135-149	chemokine (C-X-C motif) ligand 15	Mus musculus	43-47
11490344-4	2001	METHODS: Murine thioglycolate--elicited peritoneal exudative macrophages (PEMs) were used to model the effects of HTS on IL-10 release from Kupffer cells.	Thioglycolates	16-29	interleukin 10	Mus musculus	121-126
11442523-12	2001	Application of thioglycollate 0.1 mol/l, or live or formalin-inactivated C. pneumoniae (0.5 x 108 organisms), was associated with a similar increase in macrophages to that caused by MCP-1 and a significant (approximately twofold) increase in aortic diameter after 3 weeks.	Thioglycolates	15-29	C-C motif chemokine ligand 2	Homo sapiens	182-187
11396927-2	2001	Here, the mechanisms of the enhancement of the scavenger receptor activity by the substrate-bound FN was investigated using thioglycollate-induced mouse peritoneal macrophages.	Thioglycolates	124-138	fibronectin 1	Mus musculus	98-100
11380699-3	2001	Following co-incubation of either bone marrow-derived macrophages (Mphi) or thioglycollate-elicited peritoneal Mphi from CD14-/- mice with viable M. avium, tumour necrosis factor (TNF) production was significantly reduced and delayed compared to TNF secretion by infected CD14+/+ Mphi.	Thioglycolates	76-90	tumor necrosis factor	Mus musculus	246-249
11380699-3	2001	Following co-incubation of either bone marrow-derived macrophages (Mphi) or thioglycollate-elicited peritoneal Mphi from CD14-/- mice with viable M. avium, tumour necrosis factor (TNF) production was significantly reduced and delayed compared to TNF secretion by infected CD14+/+ Mphi.	Thioglycolates	76-90	CD14 antigen	Mus musculus	272-276
11201240-1	2001	Mouse thioglycollate-induced peritoneal macrophages effectively, in the absence of serum, recognized mouse polymorphonuclear leukocytes (PMNs) mildly oxidized with diamide, superoxide (hypoxanthine/xanthine oxidase) or t-butyhydroperoxide, or modified with N-ethylmaleimide (NEM).	Thioglycolates	6-20	xanthine dehydrogenase	Mus musculus	198-214
11336783-4	2001	Monolayers of thioglycollate-induced mouse peritoneal macrophages with cell surface fibronectin recognized autologous erythrocytes oxidized with an iron catalyst ADP/Fe(3+).	Thioglycolates	14-28	fibronectin 1	Mus musculus	84-95
11262203-5	2001	This CR3/CD14 receptor bias was further confirmed by using thioglycollate-elicited murine peritoneal macrophages, which have nonfunctional CR3 before activation.	Thioglycolates	59-73	integrin alpha M	Mus musculus	5-8
11262203-5	2001	This CR3/CD14 receptor bias was further confirmed by using thioglycollate-elicited murine peritoneal macrophages, which have nonfunctional CR3 before activation.	Thioglycolates	59-73	CD14 antigen	Mus musculus	9-13
11262203-5	2001	This CR3/CD14 receptor bias was further confirmed by using thioglycollate-elicited murine peritoneal macrophages, which have nonfunctional CR3 before activation.	Thioglycolates	59-73	integrin alpha M	Mus musculus	139-142
11159209-3	2001	Thioglycollate was injected intraperitoneally into BALB/c mice resulting in a dose-dependent increase in neutrophil recruitment and local inflammation, as measured by peritoneal levels of interleukin 6.	Thioglycolates	0-14	interleukin 6	Mus musculus	188-201
11159209-4	2001	At the high dose of 3% thioglycollate, antibody inhibition of the murine chemokines KC and macrophage inflammatory protein-2 caused a reduction in peritoneal neutrophil recruitment by as much as 93%.	Thioglycolates	23-37	chemokine (C-X-C motif) ligand 2	Mus musculus	91-124
11112433-4	2000	Analysis of LPS-treated thioglycolate-elicited peritoneal macrophages revealed that the rapid loss of TWEAK mRNA was due to its active destabilization.	Thioglycolates	24-37	tumor necrosis factor (ligand) superfamily, member 12	Mus musculus	102-107
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	0-14	alpha-2-macroglobulin	Mus musculus	130-150
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	0-14	alpha-2-macroglobulin	Mus musculus	152-160
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	0-14	low density lipoprotein receptor-related protein 1	Mus musculus	187-223
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	0-14	low density lipoprotein receptor-related protein 1	Mus musculus	225-228
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	0-14	PZP, alpha-2-macroglobulin like	Mus musculus	152-159
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	16-18	alpha-2-macroglobulin	Mus musculus	130-150
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	16-18	alpha-2-macroglobulin	Mus musculus	152-160
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	16-18	low density lipoprotein receptor-related protein 1	Mus musculus	187-223
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	16-18	low density lipoprotein receptor-related protein 1	Mus musculus	225-228
11527151-1	2001	Thioglycollate (TG)-elicited murine, peritoneal macrophages express two receptors for activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*)--namely, the low density lipoprotein receptor-related protein (LRP) and the alpha2M signaling receptor (alpha2MSR).	Thioglycolates	16-18	PZP, alpha-2-macroglobulin like	Mus musculus	152-159
11063620-6	2000	The selected oleanane triterpenoid, CDDO (26), was found to be a potent, multifunctional agent in various in vitro assays and to show antiinflammatory activity against thioglycollate-interferon-gamma-induced mouse peritonitis.	Thioglycolates	168-182	interferon gamma	Mus musculus	183-199
10948129-2	2000	Caveolin-1 message can also be readily detected via reverse transcription-PCR in the RAW264.7 and J774.1 macrophage-like cell lines as well as in primary thioglycolate (TG)-elicited mouse peritoneal macrophages.	Thioglycolates	154-167	caveolin 1, caveolae protein	Mus musculus	0-10
11058698-5	2000	In this study, the role of group-II PLA(2) in the Ox-LDL-induced macrophage growth was investigated using thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	106-120	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	36-42
11058698-6	2000	Thioglycollate-elicited macrophages significantly expressed group-II PLA(2) and released it into the culture medium.	Thioglycolates	0-14	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	69-75
11058698-7	2000	The Ox-LDL-induced thymidine incorporation into thioglycollate-elicited macrophages was three times higher than that into resident macrophages, whereas under the same conditions, granulocyte/macrophage colony-stimulating factor (GM-CSF) equally induced thymidine incorporation into both types of macrophages.	Thioglycolates	48-62	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	229-235
11058698-8	2000	Moreover, the Ox-LDL-induced GM-CSF release from thioglycollate-elicited macrophages was significantly higher than that from resident macrophages.	Thioglycolates	49-63	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	29-35
11058698-10	2000	These results suggest that the expression of group-II PLA(2) in thioglycollate-elicited macrophages may play an enhancing role in the Ox-LDL-induced macrophage growth through the enhancement of the GM-CSF release.	Thioglycolates	64-78	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	54-60
11058698-10	2000	These results suggest that the expression of group-II PLA(2) in thioglycollate-elicited macrophages may play an enhancing role in the Ox-LDL-induced macrophage growth through the enhancement of the GM-CSF release.	Thioglycolates	64-78	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	198-204
11068674-4	2000	Mouse thioglycollate-elicited peritoneal macrophages showed by RT-PCR constitutive steady-state levels of mRNA for TNF-type I and -type II receptors as well as IL-1 type I receptor.	Thioglycolates	6-20	interleukin 1 complex	Mus musculus	160-164
10975997-2	2000	We hypothesised that this may be due to the different capacities of the M phis studied commonly (resident, thioglycollate-elicited) to produce prostaglandin E(2)(PGE(2)) and leukotriene B(4)(LTB(4)) which inhibit and stimulate, respectively, tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) production.	Thioglycolates	107-121	tumor necrosis factor	Mus musculus	272-281
10975997-2	2000	We hypothesised that this may be due to the different capacities of the M phis studied commonly (resident, thioglycollate-elicited) to produce prostaglandin E(2)(PGE(2)) and leukotriene B(4)(LTB(4)) which inhibit and stimulate, respectively, tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) production.	Thioglycolates	107-121	interleukin 1 beta	Mus musculus	287-305
10975997-2	2000	We hypothesised that this may be due to the different capacities of the M phis studied commonly (resident, thioglycollate-elicited) to produce prostaglandin E(2)(PGE(2)) and leukotriene B(4)(LTB(4)) which inhibit and stimulate, respectively, tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) production.	Thioglycolates	107-121	interleukin 1 beta	Mus musculus	307-316
10975997-4	2000	Production of TNF-alpha, IL-1 beta, PGE(2)and LTB(4)by lipopolysaccharide-stimulated resident and thioglycollate-elicited (i.e. inflammatory) peritoneal M phis was measured.	Thioglycolates	98-112	tumor necrosis factor	Mus musculus	14-23
10833435-9	2000	Level of expression of GTPBP2 mRNA was enhanced by interferon-gamma in THP-1 cells, HeLa cells, and thioglycollate-elicited mouse peritoneal macrophages.	Thioglycolates	100-114	GTP binding protein 2	Homo sapiens	23-29
10948129-2	2000	Caveolin-1 message can also be readily detected via reverse transcription-PCR in the RAW264.7 and J774.1 macrophage-like cell lines as well as in primary thioglycolate (TG)-elicited mouse peritoneal macrophages.	Thioglycolates	169-171	caveolin 1, caveolae protein	Mus musculus	0-10
10725698-6	2000	Thioglycolate-elicited peritoneal macrophages expressed TLR4-MD-2, which was rapidly down-regulated in the presence of LPS.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	56-60
10805209-9	2000	On the other hand, thioglycolate-elicited peritoneal macrophages did not respond to IP-10, although they did show a response to RANTES, MCP-1 and MIP-1alpha.	Thioglycolates	19-32	chemokine (C-C motif) ligand 5	Mus musculus	128-134
10805209-9	2000	On the other hand, thioglycolate-elicited peritoneal macrophages did not respond to IP-10, although they did show a response to RANTES, MCP-1 and MIP-1alpha.	Thioglycolates	19-32	chemokine (C-C motif) ligand 2	Mus musculus	136-141
10805209-9	2000	On the other hand, thioglycolate-elicited peritoneal macrophages did not respond to IP-10, although they did show a response to RANTES, MCP-1 and MIP-1alpha.	Thioglycolates	19-32	chemokine (C-C motif) ligand 3	Mus musculus	146-156
10725698-6	2000	Thioglycolate-elicited peritoneal macrophages expressed TLR4-MD-2, which was rapidly down-regulated in the presence of LPS.	Thioglycolates	0-13	lymphocyte antigen 96	Mus musculus	61-65
10725698-6	2000	Thioglycolate-elicited peritoneal macrophages expressed TLR4-MD-2, which was rapidly down-regulated in the presence of LPS.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	119-122
10831379-2	2000	PM from normal uninfected mice showed either an initial high (C3H/HeJ) or a neglected (BALB/c) level of IL-1alpha activity, respectively, probably due to thioglycollate stimulation.	Thioglycolates	154-168	interleukin 1 alpha	Mus musculus	104-113
10702423-5	2000	Also, when compared to cells from gal3(+/+) mice, thioglycollate-elicited inflammatory cells from gal3(-/-) mice exhibited significantly lower levels of NF-kappaB response.	Thioglycolates	50-64	lectin, galactose binding, soluble 3	Mus musculus	98-102
10702423-5	2000	Also, when compared to cells from gal3(+/+) mice, thioglycollate-elicited inflammatory cells from gal3(-/-) mice exhibited significantly lower levels of NF-kappaB response.	Thioglycolates	50-64	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	153-162
10859485-5	2000	Stimulation of thioglycolate-elicited peritoneal macrophages with LPS (20 microg/ml), recombinant interferon-gamma (rIFN-gamma, 100 U/ml), and LPS plus rIFN-gamma induced SOM and SP.	Thioglycolates	15-28	interferon gamma	Mus musculus	98-114
10629036-5	2000	Inflammatory challenges, including thioglycolate-induced peritonitis and infection with Trichinella spiralis, stimulated similar responses in Galpha15(-/-) adults and wild-type siblings.	Thioglycolates	35-48	guanine nucleotide binding protein, alpha 15	Mus musculus	142-150
10629036-6	2000	Agonist-stimulated Ca(2+) release from intracellular stores was assayed to identify signaling defects in primary cultures of thioglycolate-elicited macrophages isolated from Galpha15(-/-) mice.	Thioglycolates	125-138	guanine nucleotide binding protein, alpha 15	Mus musculus	174-182
10639139-5	2000	The rate of transferrin recycling in thioglycollate-elicited murine peritoneal macrophages (thio-macrophages) was exceedingly rapid, with exocytic rate constants that were 2- to 3-fold higher than those of most other cells.	Thioglycolates	37-51	transferrin	Mus musculus	12-23
10648004-5	2000	The present studies, done in thioglycollate-elicited peritoneal macrophages, confirm that macrosialin is predominantly intracellular but show clearly that 10-15% of it is expressed on the cell surface.	Thioglycolates	29-43	CD68 antigen	Mus musculus	90-101
11220678-5	2000	On the other hand, NK cells significantly potentiated the nitric oxide-mediated cryptococcocidal activity of thioglycolate-elicited peritoneal macrophages obtained from SCID mice upon stimulation with IL-12 and IL-18.	Thioglycolates	109-122	interleukin 18	Mus musculus	211-216
10859485-5	2000	Stimulation of thioglycolate-elicited peritoneal macrophages with LPS (20 microg/ml), recombinant interferon-gamma (rIFN-gamma, 100 U/ml), and LPS plus rIFN-gamma induced SOM and SP.	Thioglycolates	15-28	interferon gamma	Rattus norvegicus	116-126
10859485-5	2000	Stimulation of thioglycolate-elicited peritoneal macrophages with LPS (20 microg/ml), recombinant interferon-gamma (rIFN-gamma, 100 U/ml), and LPS plus rIFN-gamma induced SOM and SP.	Thioglycolates	15-28	interferon gamma	Rattus norvegicus	152-162
10362674-9	1999	Transmigration of neutrophils into the peritoneum following thioglycollate injection was also significantly augmented in nNOS -/- and ecNOS -/- mice.	Thioglycolates	60-74	nitric oxide synthase 1, neuronal	Mus musculus	121-125
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	interleukin 1 alpha	Mus musculus	38-47
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	interleukin 1 beta	Mus musculus	49-57
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	interleukin 1 receptor antagonist	Mus musculus	59-65
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	interleukin 6	Mus musculus	71-75
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon	Mus musculus	142-156
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	189-195
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	peripheral blood stem cell response to granulocyte colony stimulating factor 1	Mus musculus	197-202
10570287-8	1999	RNase-mapping analysis indicated that IL-1alpha, IL-1beta, IL-1Ra, and IL-6 mRNA levels are constitutively elevated in thioglycolate-elicited IkappaBepsilon-null macrophages in contrast to GM-CSF, G-CSF, and IFN-gamma, which remain undetectable.	Thioglycolates	119-132	interferon gamma	Mus musculus	208-217
10614778-3	1999	We show that, in contrast to macrophages from normal mice, both bone marrow-derived macrophages (BMDM) and thioglycollate-elicited macrophages obtained from IL-10-/- mice can kill L. monocytogenes.	Thioglycolates	107-121	interleukin 10	Mus musculus	157-162
10614778-4	1999	Treatment with anti-IL-10 monoclonal antibody (mAb) enables BMDM from normal mice and thioglycollate-elicited macrophages from RAG-2-/- mice (which lack T or B cell-derived IL-10) to kill L. monocytogenes, and concurrently down-regulates the expression of surface IL-10.	Thioglycolates	86-100	interleukin 10	Mus musculus	20-25
10614778-4	1999	Treatment with anti-IL-10 monoclonal antibody (mAb) enables BMDM from normal mice and thioglycollate-elicited macrophages from RAG-2-/- mice (which lack T or B cell-derived IL-10) to kill L. monocytogenes, and concurrently down-regulates the expression of surface IL-10.	Thioglycolates	86-100	recombination activating gene 2	Mus musculus	127-132
10500197-5	1999	PE(-/-) mice, ELP(-/-) mice, and mice missing both P- and L-selectins (PL(-/-)) show drastic reductions in leukocyte rolling and in extravasation of neutrophils in thioglycollate-induced peritonitis.	Thioglycolates	164-178	selectin, platelet	Mus musculus	51-69
10817546-2	1999	Thioglycolate-elicited rat peritoneal macrophages and coronary endothelium of isolated guinea pig heart were used as assay systems for NOS-2 and NOS-3, respectively.	Thioglycolates	0-13	nitric oxide synthase, inducible	Cavia porcellus	135-140
10817546-2	1999	Thioglycolate-elicited rat peritoneal macrophages and coronary endothelium of isolated guinea pig heart were used as assay systems for NOS-2 and NOS-3, respectively.	Thioglycolates	0-13	nitric oxide synthase, endothelial	Cavia porcellus	145-150
10362674-9	1999	Transmigration of neutrophils into the peritoneum following thioglycollate injection was also significantly augmented in nNOS -/- and ecNOS -/- mice.	Thioglycolates	60-74	nitric oxide synthase 3, endothelial cell	Mus musculus	134-139
10339590-3	1999	The present studies show that lipid microemulsions prepared from OxLDL bind to thioglycollate-elicited macrophages at 4 degrees C in a saturable fashion and inhibit the binding of intact OxLDL and also of the apoB from OxLDL.	Thioglycolates	79-93	apolipoprotein B	Mus musculus	209-213
10380903-2	1999	We show here that thioglycollate-elicited macrophages acquire cytotoxic activity when cocultured with Mycoplasma arginini-infected YAC-1 tumor cells and release TNF and NO.	Thioglycolates	18-32	ADP-ribosyltransferase 1	Mus musculus	131-136
10380903-2	1999	We show here that thioglycollate-elicited macrophages acquire cytotoxic activity when cocultured with Mycoplasma arginini-infected YAC-1 tumor cells and release TNF and NO.	Thioglycolates	18-32	tumor necrosis factor	Mus musculus	161-164
10380903-7	1999	These results indicate that M. arginini activates thioglycollate-elicited murine macrophages for NO and TNF release increasing their cytotoxic activity toward YAC-1 cells and that this activity is dependent on NO but not TNF release.	Thioglycolates	50-64	tumor necrosis factor	Mus musculus	104-107
10380903-7	1999	These results indicate that M. arginini activates thioglycollate-elicited murine macrophages for NO and TNF release increasing their cytotoxic activity toward YAC-1 cells and that this activity is dependent on NO but not TNF release.	Thioglycolates	50-64	ADP-ribosyltransferase 1	Mus musculus	159-164
10380903-7	1999	These results indicate that M. arginini activates thioglycollate-elicited murine macrophages for NO and TNF release increasing their cytotoxic activity toward YAC-1 cells and that this activity is dependent on NO but not TNF release.	Thioglycolates	50-64	tumor necrosis factor	Mus musculus	221-224
10380903-0	1999	Mycoplasma arginini enhances cytotoxicity of thioglycollate-elicited murine macrophages toward YAC-1 tumor cells through production of NO.	Thioglycolates	45-59	ADP-ribosyltransferase 1	Mus musculus	95-100
9921279-0	1998	Thioglycollate-elicited murine macrophages are cytotoxic to Mycoplasma arginini-infected YAC-1 tumor cells.	Thioglycolates	0-14	ADP-ribosyltransferase 1	Mus musculus	89-94
10198263-1	1999	Previously CD11a or leukocyte function-associated antigen alpha-1 was found to be induced at the surface protein level in thioglycolate-elicited peritoneal macrophages by bacterial lipopolysaccharide and interferon-gamma.	Thioglycolates	122-135	integrin subunit alpha L	Homo sapiens	11-16
10198263-1	1999	Previously CD11a or leukocyte function-associated antigen alpha-1 was found to be induced at the surface protein level in thioglycolate-elicited peritoneal macrophages by bacterial lipopolysaccharide and interferon-gamma.	Thioglycolates	122-135	interferon gamma	Homo sapiens	204-220
10068127-3	1999	In this study, MIF-A3 was evaluated for its effect on secretion of IL-1beta, IL-6, IL-10, TNFalpha and GM-CSF in C57BL/6 murine thioglycolate-elicited peritoneal-derived macrophages, with and without pre-incubation with affinity purified goat anti-MIF-A3 IgG, using ELISA cytokine kit analysis.	Thioglycolates	128-141	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	103-109
9892616-5	1999	Thioglycollate elicited peritoneal exudates in uninfected MIF-/- mice, but showed normal neutrophil accumulation.	Thioglycolates	0-14	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	58-61
10027722-6	1999	On the other hand, when peritoneal cells were induced to differentiate into macrophages by treating in vivo the animals with thioglycollate before peritoneal harvesting, they completely lost the ability to acquire in vitro the dendritic phenotype in response to GM-CSF, either used alone or in combination with TNF-alpha.	Thioglycolates	125-139	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	262-268
10027722-6	1999	On the other hand, when peritoneal cells were induced to differentiate into macrophages by treating in vivo the animals with thioglycollate before peritoneal harvesting, they completely lost the ability to acquire in vitro the dendritic phenotype in response to GM-CSF, either used alone or in combination with TNF-alpha.	Thioglycolates	125-139	tumor necrosis factor	Mus musculus	311-320
9862711-4	1998	In contrast, we have found that many thioglycollate-induced adherent peritoneal macrophages, but not resident peritoneal macrophages, from both MRL/lpr and MRL+/+ mice atypically underwent DNA synthesis even in the absence of added CSF-1.	Thioglycolates	37-51	Fas (TNF receptor superfamily member 6)	Mus musculus	148-151
9862711-4	1998	In contrast, we have found that many thioglycollate-induced adherent peritoneal macrophages, but not resident peritoneal macrophages, from both MRL/lpr and MRL+/+ mice atypically underwent DNA synthesis even in the absence of added CSF-1.	Thioglycolates	37-51	colony stimulating factor 1 (macrophage)	Mus musculus	232-237
9813061-5	1998	Utilizing murine RAW264.7 macrophages and thioglycollate-elicited peritoneal macrophages, we demonstrate that angiostatin-like fragments are generated as a byproduct of the proteolytic regulation of membrane-bound plasmin.	Thioglycolates	42-56	plasminogen	Mus musculus	110-121
9813061-10	1998	Lavage fluid recovered from the peritoneal cavities of mice previously injected with thioglycollate contained angiostatin-like plasmin fragments similar to those generated in vitro.	Thioglycolates	85-99	plasminogen	Mus musculus	110-121
9863660-8	1998	NA and Ad (1-100 microM) also decreased MIP-1alpha production in thioglycollate-elicited murine peritoneal macrophages.	Thioglycolates	65-79	chemokine (C-C motif) ligand 3	Mus musculus	40-50
9921279-4	1998	Thioglycollate-elicited macrophages from male BALB/c mice were co-cultured for 20 h with YAC-1 tumor cells infected or not with Mycoplasma arginini.	Thioglycolates	0-14	ADP-ribosyltransferase 1	Mus musculus	89-94
9921279-6	1998	Thioglycollate-elicited macrophages co-cultured with noninfected YAC-1 cells showed low cytotoxic activity (34.7 +/- 8.6%) and low production of NO (4.7 +/- 3.1 microM NO2-).	Thioglycolates	0-14	ADP-ribosyltransferase 1	Mus musculus	65-70
9738665-6	1998	However, the response was more prolonged in B6 mice, such that B6/gld and B6/lpr mice had fewer neutrophils at 6 h after TG administration than did B6 mice.	Thioglycolates	121-123	Fas (TNF receptor superfamily member 6)	Mus musculus	77-80
9784546-7	1998	In D-galactosamine-sensitized mice, however, thioglycolate treatment significantly decreased mortality due to LPS, as well as levels of circulating TNF-alpha and IL-6.	Thioglycolates	45-58	toll-like receptor 4	Mus musculus	110-113
9784546-7	1998	In D-galactosamine-sensitized mice, however, thioglycolate treatment significantly decreased mortality due to LPS, as well as levels of circulating TNF-alpha and IL-6.	Thioglycolates	45-58	tumor necrosis factor	Mus musculus	148-157
9784546-7	1998	In D-galactosamine-sensitized mice, however, thioglycolate treatment significantly decreased mortality due to LPS, as well as levels of circulating TNF-alpha and IL-6.	Thioglycolates	45-58	interleukin 6	Mus musculus	162-166
9725248-3	1998	Both LPS and the cell-permeable ceramide analogue, C2 ceramide, induced significant cell death in IFN-gamma-activated, thioglycollate-elicited peritoneal macrophages after 48 and 24 h, respectively.	Thioglycolates	119-133	interferon gamma	Mus musculus	98-107
9738665-7	1998	Further studies showed that 4 h TG-elicited neutrophils from B6, B6/gld and B6/lpr mice undergo apoptosis in vitro at similar rates (as assessed through flow cytometry by the decrease in forward angle light-scatter and externalization of phosphatidylserine (PS; as detected by Annexin V-FITC) that occur as neutrophils undergo apoptosis).	Thioglycolates	32-34	Fas (TNF receptor superfamily member 6)	Mus musculus	79-82
9738665-7	1998	Further studies showed that 4 h TG-elicited neutrophils from B6, B6/gld and B6/lpr mice undergo apoptosis in vitro at similar rates (as assessed through flow cytometry by the decrease in forward angle light-scatter and externalization of phosphatidylserine (PS; as detected by Annexin V-FITC) that occur as neutrophils undergo apoptosis).	Thioglycolates	32-34	annexin A5	Mus musculus	277-286
9694732-6	1998	The macrophage colony-forming cells (M-CFCs) in a 16-hour thioglycollate-induced exudate were phenotyped as c-Fms+ERMP12-20+58+, properties consistent with their being more mature than bone marrow M-CFCs.	Thioglycolates	58-72	colony stimulating factor 1 receptor	Mus musculus	108-113
9767409-5	1998	However, 4 days after thioglycolate injection, galectin-3 mutant mice exhibited a significantly reduced number of recoverable granulocytes compared to wild-type animals.	Thioglycolates	22-35	lectin, galactose binding, soluble 3	Mus musculus	47-57
9708818-1	1998	Murine thioglycolate-induced peritoneal macrophages (MPMs) and the murine RAW264.7 macrophage-like cell line (RAW cells) constitutively produce vascular endothelial growth factor (VEGF).	Thioglycolates	7-20	vascular endothelial growth factor A	Mus musculus	144-178
9708818-1	1998	Murine thioglycolate-induced peritoneal macrophages (MPMs) and the murine RAW264.7 macrophage-like cell line (RAW cells) constitutively produce vascular endothelial growth factor (VEGF).	Thioglycolates	7-20	vascular endothelial growth factor A	Mus musculus	180-184
9464241-5	1998	Ang concentration in the serum of mice placed into the acute phase by injection with 3% thioglycollate do indeed increase transiently as is typical for APPs.	Thioglycolates	88-102	angiogenin, ribonuclease, RNase A family, 5	Mus musculus	0-3
9665390-3	1998	Thioglycollate-elicited peritoneal macrophages cultured in medium alone or in medium supplemented with MDP(Lysyl)GDP (1-100 microg per ml) expressed neither mRNA transcripts for inducible nitric oxide synthase, interleukin-1beta, and tumor necrosis factor-alpha, nor cytokine proteins and nitric oxide activity.	Thioglycolates	0-14	interleukin 1 beta	Mus musculus	211-228
9665390-3	1998	Thioglycollate-elicited peritoneal macrophages cultured in medium alone or in medium supplemented with MDP(Lysyl)GDP (1-100 microg per ml) expressed neither mRNA transcripts for inducible nitric oxide synthase, interleukin-1beta, and tumor necrosis factor-alpha, nor cytokine proteins and nitric oxide activity.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	234-261
9566020-3	1998	In vitro experiments demonstrated that esculentoside A (0.1-10 mumol/l) significantly reduced the release of TNF from the peritoneal macrophages derived from mice pretreated with thioglycolate.	Thioglycolates	179-192	tumor necrosis factor	Mus musculus	109-112
9490683-3	1998	To directly characterize plasminogen"s involvement in the inflammatory response, we used thioglycollate to induce a peritoneal inflammatory reaction in Plg(+/+), Plg(+/-), and Plg(-/-) mice.	Thioglycolates	89-103	plasminogen	Mus musculus	152-155
9514898-2	1998	When thioglycollate-elicited mouse peritoneal macrophages were stimulated with a high dose of LPS (10 micrograms/ml) in both the presence and absence of fetal calf serum, a source of LPS binding protein (LBP) necessary for the binding of LPS to CD14, NO production was observed.	Thioglycolates	5-19	lipopolysaccharide binding protein	Mus musculus	183-202
9514898-2	1998	When thioglycollate-elicited mouse peritoneal macrophages were stimulated with a high dose of LPS (10 micrograms/ml) in both the presence and absence of fetal calf serum, a source of LPS binding protein (LBP) necessary for the binding of LPS to CD14, NO production was observed.	Thioglycolates	5-19	lipopolysaccharide binding protein	Mus musculus	204-207
9514898-2	1998	When thioglycollate-elicited mouse peritoneal macrophages were stimulated with a high dose of LPS (10 micrograms/ml) in both the presence and absence of fetal calf serum, a source of LPS binding protein (LBP) necessary for the binding of LPS to CD14, NO production was observed.	Thioglycolates	5-19	CD14 antigen	Mus musculus	245-249
9499808-10	1998	We therefore evaluated the role of MCMV-induced IFN alpha beta on IFN gamma responses of bone marrow-derived (BMM phi) or thioglycollate-elicited M phi in vitro.	Thioglycolates	122-136	interferon gamma	Mus musculus	66-75
9565357-3	1998	In this study we analyzed the effect of IFN-gamma on the production of TGF-beta1 by thioglycolate-elicited mouse peritoneal macrophages under serum-free conditions.	Thioglycolates	84-97	interferon gamma	Mus musculus	40-49
9565357-3	1998	In this study we analyzed the effect of IFN-gamma on the production of TGF-beta1 by thioglycolate-elicited mouse peritoneal macrophages under serum-free conditions.	Thioglycolates	84-97	transforming growth factor, beta 1	Mus musculus	71-80
9536123-3	1998	In this in vitro study, to gain insight into GBS-macrophage interaction in the absence of type-specific antibodies, we examined the features of GBS survival in thioglycollate-elicited murine peritoneal macrophages and the effect of GBS on the protein kinase C (PKC)-dependent transduction pathway.	Thioglycolates	160-174	guanine nucleotide binding protein (G protein), beta 5	Mus musculus	144-147
9536123-3	1998	In this in vitro study, to gain insight into GBS-macrophage interaction in the absence of type-specific antibodies, we examined the features of GBS survival in thioglycollate-elicited murine peritoneal macrophages and the effect of GBS on the protein kinase C (PKC)-dependent transduction pathway.	Thioglycolates	160-174	guanine nucleotide binding protein (G protein), beta 5	Mus musculus	144-147
9342186-7	1997	The generality of this finding was confirmed by the induction of Bcl-xL in human myeloid U-937 cells, human peripheral blood monocytes exposed to phorbol ester, and mouse thioglycollate-activated and resident peritoneal macrophages.	Thioglycolates	171-185	BCL2 like 1	Homo sapiens	65-71
9366436-1	1997	We have investigated the effects of human LPS-binding protein (LBP) and human bactericidal/permeability-increasing protein (BPI) on LPS-dependent activation of mouse thioglycolate-elicited peritoneal macrophages in vitro, in comparison with human PBMCs.	Thioglycolates	166-179	lipopolysaccharide binding protein	Homo sapiens	63-66
9366436-1	1997	We have investigated the effects of human LPS-binding protein (LBP) and human bactericidal/permeability-increasing protein (BPI) on LPS-dependent activation of mouse thioglycolate-elicited peritoneal macrophages in vitro, in comparison with human PBMCs.	Thioglycolates	166-179	bactericidal permeability increasing protein	Homo sapiens	78-122
9366436-1	1997	We have investigated the effects of human LPS-binding protein (LBP) and human bactericidal/permeability-increasing protein (BPI) on LPS-dependent activation of mouse thioglycolate-elicited peritoneal macrophages in vitro, in comparison with human PBMCs.	Thioglycolates	166-179	bactericidal permeability increasing protein	Homo sapiens	124-127
9345042-5	1997	L11 blocks binding of WEHI78/24 cells, a murine monocytoid cell line, to inflamed lymph node HEV and inhibits recruitment of monocytes and neutrophils to thioglycollate-inflamed peritoneum.	Thioglycolates	154-168	skull morphology 16	Mus musculus	0-3
9342361-4	1997	However, after intraperitoneal thioglycollate injection, the number of peritoneal macrophages in CCR2-deficient mice did not rise above basal levels, whereas in wild-type mice the number of macrophages at 36 h was approximately 3.5 times the basal level.	Thioglycolates	31-45	chemokine (C-C motif) receptor 2	Mus musculus	97-101
9572047-1	1998	The effects of acidic fibroblast growth factor (aFGF) on phagocytosis in peritoneal macrophages from thioglycollate-elicited mice were examined using flow cytometry.	Thioglycolates	101-115	fibroblast growth factor 1	Mus musculus	15-46
9572047-1	1998	The effects of acidic fibroblast growth factor (aFGF) on phagocytosis in peritoneal macrophages from thioglycollate-elicited mice were examined using flow cytometry.	Thioglycolates	101-115	fibroblast growth factor 1	Mus musculus	48-52
9367849-2	1997	To explore the possibility that the interaction of phagocytes with apoptotic cells provides a negative or null signal for inflammation, we examined the cytokine production by thioglycollate-induced peritoneal exudate cells (PEC) upon interaction with a murine T cell clone (CTLL-2) cultured in the absence of interleukin-2 (IL-2).	Thioglycolates	175-189	interleukin 2	Mus musculus	309-322
9367849-2	1997	To explore the possibility that the interaction of phagocytes with apoptotic cells provides a negative or null signal for inflammation, we examined the cytokine production by thioglycollate-induced peritoneal exudate cells (PEC) upon interaction with a murine T cell clone (CTLL-2) cultured in the absence of interleukin-2 (IL-2).	Thioglycolates	175-189	interleukin 2	Mus musculus	324-328
9261342-9	1997	In vivo, Nramp1 mRNA expression could be up-regulated in macrophage populations by intraperitoneal injection of either LPS or thioglycollate.	Thioglycolates	126-140	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	Mus musculus	9-15
9335380-4	1997	Macrophage-conditioned medium (MPCM) generated from thioglycollate-elicited, lipopolysaccharide-stimulated macrophages upregulated mesangial cell fibronectin production in a dose- and time-dependent manner, independently of cell proliferation.	Thioglycolates	52-66	fibronectin 1	Rattus norvegicus	146-157
9281609-2	1997	We investigated the effect of various tea polyphenols and caffeine on the induction of NO synthase (NOS) in thioglycollate-elicited and lipopolysaccharide (LPS)-activated peritoneal macrophages.	Thioglycolates	108-122	nitric oxide synthase 2	Homo sapiens	87-98
9077544-4	1997	When challenged by thioglycollate intraperitoneally, Mac-1-deficient mice had similar levels of neutrophil accumulation in the peritoneal cavity at 1, 2, and 4 h. Treatment with mAb to LFA-1 blocked 78% of neutrophil accumulation in Mac-1-deficient mice and 58% in wild-type mice.	Thioglycolates	19-33	integrin alpha L	Mus musculus	185-190
9070320-3	1997	Treatment of thioglycollate-elicited BDF1 mouse macrophages with GM-CSF for 24 hr enhanced the anti-C. albicans activity of the macrophages in terms of inhibiting growth of the fungi.	Thioglycolates	13-27	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	65-71
9040562-1	1997	Inhibition of fatty acid oxidation by mercaptoacetate stimulates food intake of rats fed dietary fat.	Thioglycolates	38-53	FAT atypical cadherin 1	Rattus norvegicus	14-17
9111144-6	1997	Further studies showed that CD11b/CD18, CD98 and Mac-3 are major surface receptors for galectin-3 on murine peritoneal macrophages elicited by thioglycollate.	Thioglycolates	143-157	integrin alpha M	Mus musculus	28-33
9111144-6	1997	Further studies showed that CD11b/CD18, CD98 and Mac-3 are major surface receptors for galectin-3 on murine peritoneal macrophages elicited by thioglycollate.	Thioglycolates	143-157	integrin beta 2	Mus musculus	34-38
9111144-6	1997	Further studies showed that CD11b/CD18, CD98 and Mac-3 are major surface receptors for galectin-3 on murine peritoneal macrophages elicited by thioglycollate.	Thioglycolates	143-157	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	Mus musculus	40-44
9111144-6	1997	Further studies showed that CD11b/CD18, CD98 and Mac-3 are major surface receptors for galectin-3 on murine peritoneal macrophages elicited by thioglycollate.	Thioglycolates	143-157	lysosomal-associated membrane protein 2	Mus musculus	49-54
9111144-6	1997	Further studies showed that CD11b/CD18, CD98 and Mac-3 are major surface receptors for galectin-3 on murine peritoneal macrophages elicited by thioglycollate.	Thioglycolates	143-157	lectin, galactose binding, soluble 3	Mus musculus	87-97
9040562-9	1997	Both the high fat diet and mercaptoacetate injection increased plasma non-esterified fatty acid concentration, whereas plasma beta-hydroxybutyrate concentration was lowered by the high fat diet and by mercaptoacetate injection.	Thioglycolates	27-42	FAT atypical cadherin 1	Bos taurus	85-88
9040562-11	1997	Mercaptoacetate elevated plasma glucose concentrations at 2 and 3 h postinjection, possibly because plasma insulin concentration was lower.	Thioglycolates	0-15	insulin	Bos taurus	107-114
9040562-12	1997	Effects of mercaptoacetate on plasma insulin and metabolite concentrations may have been confounded by the effects of decreased feed intake.	Thioglycolates	11-26	insulin	Bos taurus	37-44
8841836-2	1996	Pre-exposure for 18 h of mouse thioglycollate-elicited peritoneal macrophages to low doses (1-10 ng/ml) of lipopolysaccharide (LPS), in the presence or absence of serum, induces on one hand a desensitization (endotoxin tolerance) for secondary TNF-alpha responses to LPS and, on the other hand, a 4 fold increase (priming) of secondary NO responses.	Thioglycolates	31-45	tumor necrosis factor	Mus musculus	244-253
8916939-5	1996	Typical eosinophil inflammatory responses to the injection of casein or thioglycollate occurred in GM-CSF -/ -mice but not in beta c -/- mice, suggesting that interleukin-5 was necessary for this response.	Thioglycolates	72-86	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	99-105
8916939-5	1996	Typical eosinophil inflammatory responses to the injection of casein or thioglycollate occurred in GM-CSF -/ -mice but not in beta c -/- mice, suggesting that interleukin-5 was necessary for this response.	Thioglycolates	72-86	interleukin 5	Mus musculus	159-172
8871663-4	1996	rhIL-11 pretreatment of thioglycollate-elicited peritoneal macrophages resulted in greater than 60% inhibition of LPS-induced production of TNF-alpha, IL-1beta, IL-12 p40, and nitric oxide.	Thioglycolates	24-38	tumor necrosis factor	Homo sapiens	140-149
8871663-4	1996	rhIL-11 pretreatment of thioglycollate-elicited peritoneal macrophages resulted in greater than 60% inhibition of LPS-induced production of TNF-alpha, IL-1beta, IL-12 p40, and nitric oxide.	Thioglycolates	24-38	interleukin 1 beta	Homo sapiens	151-159
8871663-4	1996	rhIL-11 pretreatment of thioglycollate-elicited peritoneal macrophages resulted in greater than 60% inhibition of LPS-induced production of TNF-alpha, IL-1beta, IL-12 p40, and nitric oxide.	Thioglycolates	24-38	interleukin 12b	Mus musculus	161-170
8881770-4	1996	This report documents (1) that thioglycollate-elicited peritoneal macrophages, activated with the inflammatory mediators, produced less NO and exhibited reduced cytotoxicity towards target cells when they were obtained from old animals than when they were obtained from young animals; and (2) that OPN was able to inhibit both the induced NO synthesis and cytotoxicity, but more effectively in macrophages from the young animals than those from the old animals.	Thioglycolates	31-45	secreted phosphoprotein 1	Mus musculus	298-301
8980461-4	1997	Increasing the peritoneal macrophage population (236%) by pretreating the cavities with thioglycollate enhanced the neutrophil migration induced by LTB4 (129%), but did not alter that induced by fMLP and C5a des arg.	Thioglycolates	88-102	complement C5	Rattus norvegicus	204-207
8962141-4	1996	FACS analysis of intact cells using mAb FA/11 showed small but definite surface expression of MS in resident mouse peritoneal macrophages but this was greatly enhanced with thioglycollate elicitation.	Thioglycolates	173-187	acyl-CoA synthetase long-chain family member 1	Mus musculus	0-4
8962141-4	1996	FACS analysis of intact cells using mAb FA/11 showed small but definite surface expression of MS in resident mouse peritoneal macrophages but this was greatly enhanced with thioglycollate elicitation.	Thioglycolates	173-187	CD68 antigen	Mus musculus	94-96
8943420-2	1996	Thioglycolate-elicited mouse peritoneal exudate macrophages secrete a metalloproteinase that degrades elastin.	Thioglycolates	0-13	elastin	Mus musculus	102-109
8951179-1	1996	A chemiluminescence (CL) was observed immediately after the addition of luminol to thioglycollate-elicited ICR mouse peritoneal macrophages (M phi) that had been incubated overnight with recombinant murine interferon-gamma (IFN-gamma) and lipopolysaccharides (LPS).	Thioglycolates	83-97	interferon gamma	Mus musculus	206-222
8951179-1	1996	A chemiluminescence (CL) was observed immediately after the addition of luminol to thioglycollate-elicited ICR mouse peritoneal macrophages (M phi) that had been incubated overnight with recombinant murine interferon-gamma (IFN-gamma) and lipopolysaccharides (LPS).	Thioglycolates	83-97	interferon gamma	Mus musculus	224-233
8886850-3	1996	Thioglycollate or oil-induced peritonal macrophages (Mf) of four different mouse strains treated with NM produce significantly more IL-6 than the non-treated cells.	Thioglycolates	0-14	interleukin 6	Mus musculus	132-136
8841836-2	1996	Pre-exposure for 18 h of mouse thioglycollate-elicited peritoneal macrophages to low doses (1-10 ng/ml) of lipopolysaccharide (LPS), in the presence or absence of serum, induces on one hand a desensitization (endotoxin tolerance) for secondary TNF-alpha responses to LPS and, on the other hand, a 4 fold increase (priming) of secondary NO responses.	Thioglycolates	31-45	toll-like receptor 4	Mus musculus	127-130
8841836-2	1996	Pre-exposure for 18 h of mouse thioglycollate-elicited peritoneal macrophages to low doses (1-10 ng/ml) of lipopolysaccharide (LPS), in the presence or absence of serum, induces on one hand a desensitization (endotoxin tolerance) for secondary TNF-alpha responses to LPS and, on the other hand, a 4 fold increase (priming) of secondary NO responses.	Thioglycolates	31-45	toll-like receptor 4	Mus musculus	267-270
9132179-1	1996	The feeding of cholesterol-enriched diet for 2 weeks was enough to reduce nitric oxide (NO), prostaglandin E(2) (PGE(2) and interleukin-1 (IL-1) productions in thioglycollate-elicited murine macrophages.	Thioglycolates	160-174	interleukin 1 complex	Mus musculus	124-137
8771371-2	1996	In this study we investigated the mechanisms by which LPS may be suppressing phagocytosis in thioglycolate-elicited murine peritoneal macrophages, by evaluating the effect of LPS on various components of the phagocytic machinery.	Thioglycolates	93-106	toll-like receptor 4	Mus musculus	54-57
9132179-1	1996	The feeding of cholesterol-enriched diet for 2 weeks was enough to reduce nitric oxide (NO), prostaglandin E(2) (PGE(2) and interleukin-1 (IL-1) productions in thioglycollate-elicited murine macrophages.	Thioglycolates	160-174	interleukin 1 complex	Mus musculus	139-143
7722409-5	1995	In a murine model of acute inflammation, thioglycollate-induced peritonitis, a monoclonal antibody against mouse PECAM-1 blocked emigration of leukocytes into the peritoneal cavity down to background levels.	Thioglycolates	41-55	platelet/endothelial cell adhesion molecule 1	Mus musculus	113-120
8844338-5	1995	Thioglycollate-elicited peritoneal macrophages activated in vitro with IFN-gamma exhibited dose-dependent cytotoxicity against both B16 and B16 alpha res cells, but significantly higher levels of cytotoxicity occurred with B16 alpha res targets.	Thioglycolates	0-14	interferon gamma	Mus musculus	71-80
7636210-6	1995	Latent TGF-beta activation by macrophages was characterized using serum-free cultures of resident and thioglycollate-elicited murine peritoneal macrophages that were either unstimulated or LPS-stimulated in vitro.	Thioglycolates	102-116	latent transforming growth factor beta binding protein 1	Mus musculus	7-15
7636210-8	1995	LPS-stimulated thioglycollate-elicited macrophages activated endogenous latent TGF-beta, whereas non-LPS-stimulated thioglycollate-elicited and resident macrophages generated undetectable levels of TGF-beta.	Thioglycolates	15-29	latent transforming growth factor beta binding protein 1	Mus musculus	79-87
7501421-2	1995	Thioglycollate-elicited BALB/c peritoneal macrophages treated with murine recombinant interferon-gamma (rIFN-gamma; 100 7/ml) in combination with lipopolysaccharide (LPS; 10 ng/ml) for 24 h killed E. cuniculi as determined by significant reductions in the number of parasites and percent of infected macrophages 48 h later compared with cultures treated with medium only.	Thioglycolates	0-14	interferon gamma	Mus musculus	86-102
7501421-2	1995	Thioglycollate-elicited BALB/c peritoneal macrophages treated with murine recombinant interferon-gamma (rIFN-gamma; 100 7/ml) in combination with lipopolysaccharide (LPS; 10 ng/ml) for 24 h killed E. cuniculi as determined by significant reductions in the number of parasites and percent of infected macrophages 48 h later compared with cultures treated with medium only.	Thioglycolates	0-14	interferon gamma	Rattus norvegicus	104-114
8730750-9	1996	When mice were primed with thioglycollate, TNF alpha was produced in the peritoneal cavity in response to low dose LPS (1 micrograms).	Thioglycolates	27-41	tumor necrosis factor	Mus musculus	43-52
8641750-7	1996	Thioglycolate-elicited mouse peritoneal macrophages were pretreated with various subthreshold stimulatory concentrations of LPS for 6 h, washed three times, and then stimulated with an effective stimulatory concentration of smooth LPS for 18 h. In confirmation of earlier studies, pretreatment of mouse macrophages with substimulatory doses of LPS inhibited the subsequent LPS-dependent NO production.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	124-127
8641750-7	1996	Thioglycolate-elicited mouse peritoneal macrophages were pretreated with various subthreshold stimulatory concentrations of LPS for 6 h, washed three times, and then stimulated with an effective stimulatory concentration of smooth LPS for 18 h. In confirmation of earlier studies, pretreatment of mouse macrophages with substimulatory doses of LPS inhibited the subsequent LPS-dependent NO production.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	231-234
8641750-7	1996	Thioglycolate-elicited mouse peritoneal macrophages were pretreated with various subthreshold stimulatory concentrations of LPS for 6 h, washed three times, and then stimulated with an effective stimulatory concentration of smooth LPS for 18 h. In confirmation of earlier studies, pretreatment of mouse macrophages with substimulatory doses of LPS inhibited the subsequent LPS-dependent NO production.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	231-234
8641750-7	1996	Thioglycolate-elicited mouse peritoneal macrophages were pretreated with various subthreshold stimulatory concentrations of LPS for 6 h, washed three times, and then stimulated with an effective stimulatory concentration of smooth LPS for 18 h. In confirmation of earlier studies, pretreatment of mouse macrophages with substimulatory doses of LPS inhibited the subsequent LPS-dependent NO production.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	231-234
7594498-1	1995	We have characterized the transcriptional response to IFN-gamma in two maturationally distinct macrophage populations: the mature RAW 264.7 cell line, phenotypically identical to thioglycollate-elicited peritoneal macrophages, and the less mature WEHI-3 cell line.	Thioglycolates	179-193	interferon gamma	Mus musculus	54-63
8593440-3	1995	Carboxamide-methylated light chain (G1L) from human serum IgG inhibited the secretion of tumor necrosis factor (TNF-alpha), one of the inflammatory cytokines, from adherent splenocytes and thioglycolate-induced peritoneal macrophages.	Thioglycolates	189-202	GSG1-like	Mus musculus	36-39
8593440-3	1995	Carboxamide-methylated light chain (G1L) from human serum IgG inhibited the secretion of tumor necrosis factor (TNF-alpha), one of the inflammatory cytokines, from adherent splenocytes and thioglycolate-induced peritoneal macrophages.	Thioglycolates	189-202	immunoglobulin heavy chain (V7183 family)	Mus musculus	58-61
8593440-3	1995	Carboxamide-methylated light chain (G1L) from human serum IgG inhibited the secretion of tumor necrosis factor (TNF-alpha), one of the inflammatory cytokines, from adherent splenocytes and thioglycolate-induced peritoneal macrophages.	Thioglycolates	189-202	tumor necrosis factor	Mus musculus	112-121
8593440-4	1995	The inhibition of TNF-alpha secretion by G1L was associated with disappearance of tyrosine phosphorylation on about 40 kDa protein when thioglycolate-induced peritoneal macrophages were stimulated with lipopolysaccharide (LPS).	Thioglycolates	136-149	tumor necrosis factor	Mus musculus	18-27
8593440-4	1995	The inhibition of TNF-alpha secretion by G1L was associated with disappearance of tyrosine phosphorylation on about 40 kDa protein when thioglycolate-induced peritoneal macrophages were stimulated with lipopolysaccharide (LPS).	Thioglycolates	136-149	GSG1-like	Mus musculus	41-44
7738161-5	1995	The leukocyte integrin Mac-1 (CD11b/CD18) and its beta subunit (CD18), but neither lymphocyte function-associated antigen-1 nor very late activation antigen-4, were upregulated on monocyte/macrophages elicited by CP-10(42-55), thioglycollate, and macrophage colony-stimulating factor.	Thioglycolates	227-241	integrin alpha M	Mus musculus	23-28
7738161-5	1995	The leukocyte integrin Mac-1 (CD11b/CD18) and its beta subunit (CD18), but neither lymphocyte function-associated antigen-1 nor very late activation antigen-4, were upregulated on monocyte/macrophages elicited by CP-10(42-55), thioglycollate, and macrophage colony-stimulating factor.	Thioglycolates	227-241	integrin alpha M	Mus musculus	30-35
7738161-5	1995	The leukocyte integrin Mac-1 (CD11b/CD18) and its beta subunit (CD18), but neither lymphocyte function-associated antigen-1 nor very late activation antigen-4, were upregulated on monocyte/macrophages elicited by CP-10(42-55), thioglycollate, and macrophage colony-stimulating factor.	Thioglycolates	227-241	integrin beta 2	Mus musculus	64-68
7600195-0	1995	Increased phospholipid mass with decreased arachidonoyl molecular species is associated with decreased eicosanoid synthesis and increased tumor necrosis factor synthesis by thioglycollate-elicited rat peritoneal macrophages.	Thioglycolates	173-187	tumor necrosis factor-like	Rattus norvegicus	138-159
7600195-4	1995	These results suggest that thioglycollate elicitation decreases specific arachidonic acid-containing molecular species in PlsEtn and PakCho, which may, in part, explain the decrease in eicosanoid and increase in TNF synthesis by thioglycollate-elicited macrophages.	Thioglycolates	27-41	tumor necrosis factor-like	Rattus norvegicus	212-215
7600195-4	1995	These results suggest that thioglycollate elicitation decreases specific arachidonic acid-containing molecular species in PlsEtn and PakCho, which may, in part, explain the decrease in eicosanoid and increase in TNF synthesis by thioglycollate-elicited macrophages.	Thioglycolates	229-243	tumor necrosis factor-like	Rattus norvegicus	212-215
7600195-5	1995	The differences between resident and thioglycollate-elicited macrophages in the synthesis of the eicosanoids and TNF activity was not altered by increasing either the concentration of either stimulus or the incubation time.	Thioglycolates	37-51	tumor necrosis factor-like	Rattus norvegicus	113-116
7596352-1	1995	The effect of individual unsaturated fatty acids on the release of tumour necrosis factor (TNF) and interleukin 6 (IL6) was investigated in thioglycollate-induced rat peritoneal macrophages.	Thioglycolates	140-154	tumor necrosis factor	Rattus norvegicus	67-89
7596352-1	1995	The effect of individual unsaturated fatty acids on the release of tumour necrosis factor (TNF) and interleukin 6 (IL6) was investigated in thioglycollate-induced rat peritoneal macrophages.	Thioglycolates	140-154	tumor necrosis factor	Rattus norvegicus	91-94
7596352-1	1995	The effect of individual unsaturated fatty acids on the release of tumour necrosis factor (TNF) and interleukin 6 (IL6) was investigated in thioglycollate-induced rat peritoneal macrophages.	Thioglycolates	140-154	interleukin 6	Rattus norvegicus	100-113
7596352-1	1995	The effect of individual unsaturated fatty acids on the release of tumour necrosis factor (TNF) and interleukin 6 (IL6) was investigated in thioglycollate-induced rat peritoneal macrophages.	Thioglycolates	140-154	interleukin 6	Rattus norvegicus	115-118
7600195-1	1995	Because the activation state of macrophages may alter their response to endotoxin, we compared phospholipid arachidonic acid content, and synthesis of eicosanoids and tumor necrosis factor by resident and thioglycollate-elicited rat peritoneal macrophages.	Thioglycolates	205-219	tumor necrosis factor-like	Rattus norvegicus	167-188
7600195-3	1995	Thioglycollate-elicited macrophages synthesized significantly less thromboxane B2, 6-keto-prostaglandin F1 alpha, and prostaglandin E2 and more tumor necrosis factor (TNF) activity in response to both endotoxin and A23187 than did resident macrophages.	Thioglycolates	0-14	tumor necrosis factor-like	Rattus norvegicus	144-165
7600195-3	1995	Thioglycollate-elicited macrophages synthesized significantly less thromboxane B2, 6-keto-prostaglandin F1 alpha, and prostaglandin E2 and more tumor necrosis factor (TNF) activity in response to both endotoxin and A23187 than did resident macrophages.	Thioglycolates	0-14	tumor necrosis factor-like	Rattus norvegicus	167-170
20693065-3	1994	Then the cells were washed and assessed for the following immune functions: Fc-receptor-dependent phagocytosis and lipopolysaccharide-induced release of a cytolytic protein (tumour necrosis factor, TNF) of thioglycollate-elicited peritoneal macrophages; natural killer (NK) cell activity, blastogenesis (T and B lymphocytes), and antibody synthesis (B lymphocytes) of spleen-cell suspensions.	Thioglycolates	206-220	tumor necrosis factor	Mus musculus	198-201
7842477-4	1995	When thioglycollate-elicited macrophages were treated with inhibitors of 5"-LO during activation, cytolytic capacity, nitric oxide production, and tumor necrosis factor-alpha production were significantly inhibited.	Thioglycolates	5-19	tumor necrosis factor	Homo sapiens	147-174
7829975-0	1995	LPS inhibits the intracellular growth of Legionella pneumophila in thioglycolate elicited murine peritoneal macrophages by iron-dependent, tryptophan-independent, oxygen-independent, and arginine-independent mechanisms.	Thioglycolates	67-80	toll-like receptor 4	Mus musculus	0-3
7829975-1	1995	Thioglycolate-elicited murine macrophages from genetically susceptible A/J mice activated with lipopolysaccharide (LPS) and infected with Legionella pneumophila in vitro evince marked inhibition of intracellular growth of this bacterium.	Thioglycolates	0-13	toll-like receptor 4	Mus musculus	115-118
7989773-1	1994	Translocation of protein kinase C (PKC) after PMA or LPS stimulation has been studied in thioglycolate (TGC)-elicited murine peritoneal macrophages.	Thioglycolates	89-102	protein kinase C, beta	Mus musculus	35-38
7705746-2	1994	In thioglycollate-elicited peritoneal macrophages from wild-typy (WT) mice, TNF enhanced nitric oxide (NO) release in the presence of IFN-gamma, though TNF alone was not effective.	Thioglycolates	3-17	tumor necrosis factor	Mus musculus	76-79
7705746-2	1994	In thioglycollate-elicited peritoneal macrophages from wild-typy (WT) mice, TNF enhanced nitric oxide (NO) release in the presence of IFN-gamma, though TNF alone was not effective.	Thioglycolates	3-17	tumor necrosis factor	Mus musculus	152-155
7930949-7	1994	Bone marrow-derived or thioglycollate-elicited macrophages from the NZW mouse strain, which have been reported to be deficient in their ability to produce TNF, were at least as responsive to LPS or lymphokines as those taken from the C57Bl/6 strain and were similarly affected by M-CSF and IL-10.	Thioglycolates	23-37	tumor necrosis factor	Mus musculus	155-158
7930949-7	1994	Bone marrow-derived or thioglycollate-elicited macrophages from the NZW mouse strain, which have been reported to be deficient in their ability to produce TNF, were at least as responsive to LPS or lymphokines as those taken from the C57Bl/6 strain and were similarly affected by M-CSF and IL-10.	Thioglycolates	23-37	colony stimulating factor 1 (macrophage)	Mus musculus	280-285
7930949-7	1994	Bone marrow-derived or thioglycollate-elicited macrophages from the NZW mouse strain, which have been reported to be deficient in their ability to produce TNF, were at least as responsive to LPS or lymphokines as those taken from the C57Bl/6 strain and were similarly affected by M-CSF and IL-10.	Thioglycolates	23-37	interleukin 10	Mus musculus	290-295
8062929-1	1994	The role of protein kinase C in the regulation of vacuolar-type H(+)-ATPase (V-ATPase) activity was studied in thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	111-124	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	50-75
7812678-6	1994	The addition of free arachidonic acid to cultures of LPS-stimulated, thioglycollate-elicited macrophages elevated PGE2 production and suppressed TNF alpha production in a manner similar to that observed with LPS-stimulated resident macrophages.	Thioglycolates	69-83	tumor necrosis factor	Rattus norvegicus	145-154
7812678-8	1994	Instead, the inability of indomethacin to increase TNF alpha production by thioglycollate-elicited versus resident macrophages appears to result from an inability to release arachidonate efficiently and a lower initial level of cyclooxygenase, in thioglycollate-elicited macrophages.	Thioglycolates	75-89	tumor necrosis factor	Rattus norvegicus	51-60
8077668-1	1994	The supernatant of Mycoplasma arginini-infected murine L5178Y T lymphoma cell cultures (SN-L51) synergizes with small concentrations of IFN-gamma to activate murine peritoneal, thioglycollate-elicited macrophages (M phi) to exhibit cytostatic activity against tumor cells.	Thioglycolates	177-191	interferon gamma	Mus musculus	136-145
7812678-0	1994	Regulation of lipopolysaccharide-induced tumor necrosis factor alpha production by endogenous prostaglandin E2 in rat resident and thioglycollate-elicited macrophages.	Thioglycolates	131-145	tumor necrosis factor	Rattus norvegicus	41-68
7812678-2	1994	However, we have observed that a cyclooxygenase inhibitor had different effects on TNF alpha production by resident and thioglycollate-elicited rat peritoneal macrophages.	Thioglycolates	120-134	tumor necrosis factor	Rattus norvegicus	83-92
8074719-3	1994	Similarly, rat liver mRNA for HGFL protein was upregulated to 78% above controls at 24 h after injection of thioglycollate (inducing activation of peritoneal macrophages) and to 118% at 48 h after injection of turpentine (inducing the acute phase response).	Thioglycolates	108-122	phosphoinositide-3-kinase interacting protein 1	Rattus norvegicus	30-42
8062929-1	1994	The role of protein kinase C in the regulation of vacuolar-type H(+)-ATPase (V-ATPase) activity was studied in thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	111-124	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	77-85
8039877-3	1994	GBS as well as two other gram-positive bacterial species, Staphylococcus aureus and Staphylococcus epidermidis, were found to stimulate NO production in thioglycolate-elicited murine macrophages and in the mouse macrophage cell line J774A.1 in the presence of gamma interferon.	Thioglycolates	153-166	guanine nucleotide binding protein (G protein), beta 5	Mus musculus	0-3
8039877-9	1994	Monoclonal anti-CR3 (anti-CD11b or anti-CD18) in the presence of interferon also induced NO production in thioglycolate-elicited macrophages and in J774A.1 cells but not in WEHI-3 cells.	Thioglycolates	106-119	integrin alpha M	Mus musculus	16-19
8039877-9	1994	Monoclonal anti-CR3 (anti-CD11b or anti-CD18) in the presence of interferon also induced NO production in thioglycolate-elicited macrophages and in J774A.1 cells but not in WEHI-3 cells.	Thioglycolates	106-119	integrin alpha M	Mus musculus	26-31
8039877-9	1994	Monoclonal anti-CR3 (anti-CD11b or anti-CD18) in the presence of interferon also induced NO production in thioglycolate-elicited macrophages and in J774A.1 cells but not in WEHI-3 cells.	Thioglycolates	106-119	integrin beta 2	Mus musculus	40-44
7928302-5	1994	injection of PH-I C into mice could enhance the phagocytic activity of thioglycollate-elicited peritoneal macrophages.	Thioglycolates	71-85	glucose-6-phosphate isomerase 1	Mus musculus	13-17
8031127-6	1994	The recognition by thioglycollate-induced macrophages was not inhibited by glycophorin A but was partially inhibited by L-fucose, lactoferrin, and oligosaccharides from band 3 glycoprotein.	Thioglycolates	19-33	lactotransferrin	Mus musculus	130-141
8031127-8	1994	These results suggest that sialosaccharide chains of ADP/Fe(3+)-oxidized erythrocytes, possibly those on glycophorin A, are mainly involved in the recognition by resident macrophages, and poly-N-acetyllactosaminyl saccharide chains, possibly those on band 3, are partly involved in the recognition both by resident and thioglycollate-induced macrophages.	Thioglycolates	319-333	glycophorin A	Mus musculus	105-118
8174736-4	1994	INTERVENTIONS: Intraperitoneal injection of thioglycolate was used to elicit large numbers of activated peritoneal macrophages (mean 24.4 x 10(6) leukocytes/animal) in female CD-1 mice.	Thioglycolates	44-57	CD1 antigen complex	Mus musculus	175-179
8176217-4	1994	That is, in response to thioglycollate in the peritoneum, neutrophils migrated in normal numbers to the peritoneal cavity and expressed the normal activation phenotype of high Mac-1 and low Mel-14 Ag levels.	Thioglycolates	24-38	integrin alpha M	Mus musculus	176-181
8031051-2	1994	Midazolam and 4"-chlorodiazepam significantly suppressed LPS (1-microgram/ml)-induced TNF activity in thioglycolate-elicited mouse macrophages.	Thioglycolates	102-115	toll-like receptor 4	Mus musculus	57-60
8031051-2	1994	Midazolam and 4"-chlorodiazepam significantly suppressed LPS (1-microgram/ml)-induced TNF activity in thioglycolate-elicited mouse macrophages.	Thioglycolates	102-115	tumor necrosis factor	Mus musculus	86-89
8031051-7	1994	Intravenous 4"-chlorodiazepam (5 mg/kg of body weight) significantly suppressed LPS (100-micrograms)-induced TNF activity of sera (2 h postchallenge with LPS) from thioglycolate-treated mice.	Thioglycolates	164-177	toll-like receptor 4	Mus musculus	80-83
8031051-7	1994	Intravenous 4"-chlorodiazepam (5 mg/kg of body weight) significantly suppressed LPS (100-micrograms)-induced TNF activity of sera (2 h postchallenge with LPS) from thioglycolate-treated mice.	Thioglycolates	164-177	tumor necrosis factor	Mus musculus	109-112
8031051-7	1994	Intravenous 4"-chlorodiazepam (5 mg/kg of body weight) significantly suppressed LPS (100-micrograms)-induced TNF activity of sera (2 h postchallenge with LPS) from thioglycolate-treated mice.	Thioglycolates	164-177	toll-like receptor 4	Mus musculus	154-157
8045673-6	1994	In contrast, both ET-18-O_OCH3 and PAF stimulated TNF alpha release by thioglycollate-elicited macrophages in the absence of LPS although release was greater in the presence of this co-stimulus.	Thioglycolates	71-85	patchy fur	Mus musculus	35-38
8045673-6	1994	In contrast, both ET-18-O_OCH3 and PAF stimulated TNF alpha release by thioglycollate-elicited macrophages in the absence of LPS although release was greater in the presence of this co-stimulus.	Thioglycolates	71-85	tumor necrosis factor	Mus musculus	50-59
8308013-3	1994	Only thioglycollate-elicited macrophages express cell surface Mac-2, and binding is mostly (> 80%) a result of affinity for cell surface carbohydrate structures.	Thioglycolates	5-19	lectin, galactose binding, soluble 3	Mus musculus	62-67
8145025-6	1994	Peritoneal macrophage populations elicited by intraperitoneal injection of thioglycollate were uniformly positive for surface CD43, although the level of expression was lower than that found on monocytes.	Thioglycolates	75-89	sialophorin	Rattus norvegicus	126-130
8019836-4	1994	Mercaptoacetate induced Fos-li in the nucleus of the solitary tract (NTS), the central subnucleus of the lateral parabrachial nucleus (1PBN), the central nucleus of the amygdala (CNA, lateral part) and the dorsal motor nucleus of the vagus (DMV).	Thioglycolates	0-15	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	24-27
8308013-4	1994	Mac-2 surface expression is markedly reduced upon further activation of thioglycollate-elicited macrophages with bacterial lipopolysaccharide in vitro.	Thioglycolates	72-86	lectin, galactose binding, soluble 3	Mus musculus	0-5
8308013-6	1994	Chemical cross-linking experiments have identified binding of endogenous cell-surface Mac-2 to three glycoproteins of molecular masses of 92, 125, and 180 kDa containing alpha-galactosyl and polylactosamine structures on thioglycollate-elicited macrophages.	Thioglycolates	221-235	lectin, galactose binding, soluble 3	Mus musculus	86-91
8308013-7	1994	The restricted cell surface distribution of Mac-2 on thioglycollate-elicited peritoneal macrophages, a population of recently recruited monocytes, suggests a role(s) in early events of macrophage infiltration and tissue fixation such as extravasion and cell-matrix interactions.	Thioglycolates	53-67	lectin, galactose binding, soluble 3	Mus musculus	44-49
8118877-2	1994	OA (100 nM) was able to stimulate accumulation of TNF alpha and IP-10 mRNAs in thioglycollate-elicited peritoneal macrophages from C57B1/6 mice.	Thioglycolates	79-93	tumor necrosis factor	Mus musculus	50-59
7512741-8	1994	The ApN catalytic activity and mRNA levels are increased in thioglycollate-elicited as compared to resident peritoneal macrophages.	Thioglycolates	60-74	alanyl (membrane) aminopeptidase	Mus musculus	4-7
7512741-9	1994	RT-PCR analysis identified a 0.7 kb fragment of the ApN coding sequence which was identical in mouse kidney and thioglycollate-elicited peritoneal macrophages and which has 89% identity with the corresponding rat kidney ApN cDNA sequence.	Thioglycolates	112-126	alanyl (membrane) aminopeptidase	Mus musculus	52-55
8311322-2	1994	Therefore, the authors examined the effect of ketamine on lipopolysaccharide (LPS)-induced and calcium ionophore A23187-induced tumor necrosis factor alpha (TNF-alpha) production in thioglycolate (TGC)-elicited peritoneal macrophages (MPs) in ddY mice.	Thioglycolates	182-195	tumor necrosis factor	Mus musculus	128-155
8311322-2	1994	Therefore, the authors examined the effect of ketamine on lipopolysaccharide (LPS)-induced and calcium ionophore A23187-induced tumor necrosis factor alpha (TNF-alpha) production in thioglycolate (TGC)-elicited peritoneal macrophages (MPs) in ddY mice.	Thioglycolates	182-195	tumor necrosis factor	Mus musculus	157-166
8311322-2	1994	Therefore, the authors examined the effect of ketamine on lipopolysaccharide (LPS)-induced and calcium ionophore A23187-induced tumor necrosis factor alpha (TNF-alpha) production in thioglycolate (TGC)-elicited peritoneal macrophages (MPs) in ddY mice.	Thioglycolates	197-200	tumor necrosis factor	Mus musculus	157-166
7509725-4	1994	Calcium ionophores and thapsigargin trigger NO synthase activity in macrophages primed in vivo by TDM, in thioglycollate-elicited macrophages primed in vitro by IFN-gamma, and in IFN-gamma-treated EMT6 adenocarcinoma cells.	Thioglycolates	106-120	interferon gamma	Mus musculus	161-170
7509725-4	1994	Calcium ionophores and thapsigargin trigger NO synthase activity in macrophages primed in vivo by TDM, in thioglycollate-elicited macrophages primed in vitro by IFN-gamma, and in IFN-gamma-treated EMT6 adenocarcinoma cells.	Thioglycolates	106-120	interferon gamma	Mus musculus	179-188
8118877-2	1994	OA (100 nM) was able to stimulate accumulation of TNF alpha and IP-10 mRNAs in thioglycollate-elicited peritoneal macrophages from C57B1/6 mice.	Thioglycolates	79-93	chemokine (C-X-C motif) ligand 10	Mus musculus	64-69
8341679-3	1993	In thioglycollate-elicited macrophages from wild-type mice, tumor necrosis factor (TNF) alone was virtually ineffective in inducing release of NO2- (the endproduct of nitric oxide generation), but TNF enhanced NO2- release in the presence of IFN-gamma.	Thioglycolates	3-17	tumor necrosis factor	Mus musculus	60-81
8020558-1	1994	Mac-2 antigen, a 32-kDa murine macrophage cell-surface protein expressed on thioglycollate-elicited peritoneal exudate cells at higher levels than other macrophages, is a member of the S-(soluble) galactoside-binding lectin family with homologies to carbohydrate-binding proteins of other cell types.	Thioglycolates	76-90	lectin, galactose binding, soluble 3	Mus musculus	0-13
8050748-7	1994	Recombinant murine interferon-gamma (mIFN-gamma, 100 mu/ml) alone or in combination with lipopolysaccharide (LPS; 10 ng/ml) could activate thioglycollate-induced peritoneal murine macrophages to destroy E. cuniculi.	Thioglycolates	139-153	interferon gamma	Mus musculus	37-47
8275549-6	1993	The activity of lymphocyte citrate synthase was lowered by thioglycollate (39 per cent) and tumour-implantation (46 per cent).	Thioglycolates	59-73	citrate synthase	Rattus norvegicus	27-43
8263420-3	1993	We have used the sensitive polymerase chain reaction (PCR) technique to demonstrate expression of HSL mRNA in resident and thioglycollate-elicited mouse peritoneal macrophages, as well as in the P388D1 mouse macrophage cell line.	Thioglycolates	123-137	lipase, hormone sensitive	Mus musculus	98-101
8403518-4	1993	avium differentially stimulated TNF production in thioglycollate-elicited macrophages in a dose-dependent manner.	Thioglycolates	50-64	tumor necrosis factor	Mus musculus	32-35
8404602-5	1993	Isolated thioglycolate-induced peritoneal macrophages contained PRL-R, and the PRL-R monoclonal U5 gave the best separation from unstained cells.	Thioglycolates	9-22	prolactin receptor	Mus musculus	64-69
7901310-1	1993	Taxol is a potent, microtubule-stabilizing, antineoplastic drug that induces interleukin-1-beta (IL-1-beta) and tumor necrosis factor-alpha (TNF-alpha) release by thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	163-176	interleukin 1 beta	Mus musculus	77-95
7901310-1	1993	Taxol is a potent, microtubule-stabilizing, antineoplastic drug that induces interleukin-1-beta (IL-1-beta) and tumor necrosis factor-alpha (TNF-alpha) release by thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	163-176	interleukin 1 beta	Mus musculus	97-106
7901310-1	1993	Taxol is a potent, microtubule-stabilizing, antineoplastic drug that induces interleukin-1-beta (IL-1-beta) and tumor necrosis factor-alpha (TNF-alpha) release by thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	163-176	tumor necrosis factor	Mus musculus	112-139
7901310-1	1993	Taxol is a potent, microtubule-stabilizing, antineoplastic drug that induces interleukin-1-beta (IL-1-beta) and tumor necrosis factor-alpha (TNF-alpha) release by thioglycolate-elicited mouse peritoneal macrophages.	Thioglycolates	163-176	tumor necrosis factor	Mus musculus	141-150
8242347-3	1993	The antimetabolite mercaptoacetate, in contrast, which blocks fatty acid oxidation, produced no significant change and actually tended to reduce NPY levels in the ARC.	Thioglycolates	19-34	neuropeptide Y	Rattus norvegicus	145-148
8294481-4	1994	The monomeric ReLPS was 179- and 1000-fold more active than the aggregated ReLPS preparation in the LAL assay and induction of Egr-1 mRNA by thioglycollate-elicited murine peritoneal macrophages, respectively.	Thioglycolates	141-155	early growth response 1	Mus musculus	127-132
8297115-3	1993	Macrophages from Spon-2 tumour bearing mice behaved like "primed" thioglycollate-elicited macrophages and produced a tumouricidal response to 5,6-MeXXA which was significantly higher than that obtained from resident peritoneal macrophages from non-tumour bearing mice.	Thioglycolates	66-80	spondin 2, extracellular matrix protein	Mus musculus	17-23
8394371-10	1993	The syndecan-1 gene is active in blood monocytes as well as resident and thioglycollate-elicited mouse peritoneal macrophages, but expression of the proteoglycan is regulated at two levels.	Thioglycolates	73-87	syndecan 1	Mus musculus	4-14
8341679-3	1993	In thioglycollate-elicited macrophages from wild-type mice, tumor necrosis factor (TNF) alone was virtually ineffective in inducing release of NO2- (the endproduct of nitric oxide generation), but TNF enhanced NO2- release in the presence of IFN-gamma.	Thioglycolates	3-17	tumor necrosis factor	Mus musculus	83-86
8503836-5	1993	The present experiments examine the effect of phorbol ester, an activator of protein kinase C, on the apoE expression in mouse thioglycollate-elicited peritoneal macrophages.	Thioglycolates	127-141	apolipoprotein E	Mus musculus	102-106
8510131-2	1993	M1Av stimulated thioglycolate-induced peritoneal macrophages from C3H/HeN and C3H/HeJ mice to release cell-free tumour necrosis factor (TNF) and interleukin (IL)-6, and a cell-associated thymocyte activating factor, probably IL-1.	Thioglycolates	16-29	tumor necrosis factor	Mus musculus	136-139
8510131-2	1993	M1Av stimulated thioglycolate-induced peritoneal macrophages from C3H/HeN and C3H/HeJ mice to release cell-free tumour necrosis factor (TNF) and interleukin (IL)-6, and a cell-associated thymocyte activating factor, probably IL-1.	Thioglycolates	16-29	interleukin 6	Mus musculus	145-163
8510131-2	1993	M1Av stimulated thioglycolate-induced peritoneal macrophages from C3H/HeN and C3H/HeJ mice to release cell-free tumour necrosis factor (TNF) and interleukin (IL)-6, and a cell-associated thymocyte activating factor, probably IL-1.	Thioglycolates	16-29	interleukin 1 complex	Mus musculus	225-229
8104878-3	1993	Flow cytometric analysis of bone marrow-derived M phi cultured in the presence of M-CSF, of thioglycollate-elicited peritoneal M phi and of M1 myeloblasts differentiated by lipopolysaccharide (LPS) treatment revealed that ICAM-1 is increasingly expressed during monocytic maturation.	Thioglycolates	92-106	colony stimulating factor 1 (macrophage)	Mus musculus	82-87
8104878-3	1993	Flow cytometric analysis of bone marrow-derived M phi cultured in the presence of M-CSF, of thioglycollate-elicited peritoneal M phi and of M1 myeloblasts differentiated by lipopolysaccharide (LPS) treatment revealed that ICAM-1 is increasingly expressed during monocytic maturation.	Thioglycolates	92-106	intercellular adhesion molecule 1	Mus musculus	222-228
8486654-2	1993	We have isolated cDNA clones encoding macrosialin from a thioglycollate-elicited peritoneal macrophage cDNA library by transient expression in COS cells and panning with the anti-macrosialin monoclonal antibody FA/11.	Thioglycolates	57-71	CD68 antigen	Mus musculus	38-49
8452867-4	1993	Upon stimulation by thioglycollate, PA activity increased and PAI activity decreased, thus raising the fibrinolytic balance in these macrophages.	Thioglycolates	20-34	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	62-65
8452867-5	1993	Upon incubation of resident or thioglycollate-activated macrophages by lipopolysaccharide (LPS), the PA level was depressed while the PAI level was increased, resulting in a large drop in the total fibrinolytic balance of the activated cells.	Thioglycolates	31-45	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	134-137
8452867-6	1993	When resident or thioglycollate-activated macrophages were incubated with the anti-inflammatory agent dexamethasone, the drug depressed both the expressions of PA and PAI, in the lysate and conditioned medium of both cell types.	Thioglycolates	17-31	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	167-170
8452867-7	1993	Thus cell-bound or secreted forms of macrophage PA and PAI activities were either increased or decreased in response to thioglycollate, LPS or dexamethasone challenge.	Thioglycolates	120-134	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	55-58
8325351-3	1993	We assessed the effect of age on interleukin-1 (IL-1), tumor necrosis factor (TNF), and interleukin-6 (IL-6) in unelicited, thioglycollate (TG)-elicited, and complete Freund"s adjuvant (CFA)-elicited peritoneal macrophages.	Thioglycolates	124-138	interleukin 6	Mus musculus	88-101
8325351-3	1993	We assessed the effect of age on interleukin-1 (IL-1), tumor necrosis factor (TNF), and interleukin-6 (IL-6) in unelicited, thioglycollate (TG)-elicited, and complete Freund"s adjuvant (CFA)-elicited peritoneal macrophages.	Thioglycolates	124-138	interleukin 6	Mus musculus	103-107
8325351-3	1993	We assessed the effect of age on interleukin-1 (IL-1), tumor necrosis factor (TNF), and interleukin-6 (IL-6) in unelicited, thioglycollate (TG)-elicited, and complete Freund"s adjuvant (CFA)-elicited peritoneal macrophages.	Thioglycolates	140-142	interleukin 6	Mus musculus	88-101
8454954-2	1993	We compared the antigen-presenting activities of different subpopulations of thioglycolate-induced peritoneal macrophages from mice that were or were not treated with cyclophosphamide (CY) by several functional (adherence and phagocytosis) and morphologic (phenotypic) markers (FcR, Ia).	Thioglycolates	77-90	Fc receptor	Mus musculus	278-281
8423096-15	1993	Even in vitro, TCV-309 also inhibited LPS-induced TNF production in thioglycolate-elicited macrophages.	Thioglycolates	68-81	tumor necrosis factor	Mus musculus	50-53
8009983-2	1993	At 10(-6) and 10(-5) mol/L, WEB 2086 was found to significantly inhibit LPS induced TNF production from macrophages by activated thioglycollate solution.	Thioglycolates	129-143	tumor necrosis factor	Mus musculus	84-87
8426119-1	1993	Preculture of thioglycollate-elicited C3HeB/FeJ mouse peritoneal macrophages in vitro with subthreshold stimulatory concentrations of lipopolysaccharide (LPS) can induce hyporesponsiveness (desensitization) to both tumor necrosis factor alpha (TNF-alpha) and nitric oxide (NO) production when these cells are subsequently stimulated with 100 ng/ml of LPS.	Thioglycolates	14-28	toll-like receptor 4	Mus musculus	154-157
8426119-1	1993	Preculture of thioglycollate-elicited C3HeB/FeJ mouse peritoneal macrophages in vitro with subthreshold stimulatory concentrations of lipopolysaccharide (LPS) can induce hyporesponsiveness (desensitization) to both tumor necrosis factor alpha (TNF-alpha) and nitric oxide (NO) production when these cells are subsequently stimulated with 100 ng/ml of LPS.	Thioglycolates	14-28	tumor necrosis factor	Mus musculus	215-242
8426119-1	1993	Preculture of thioglycollate-elicited C3HeB/FeJ mouse peritoneal macrophages in vitro with subthreshold stimulatory concentrations of lipopolysaccharide (LPS) can induce hyporesponsiveness (desensitization) to both tumor necrosis factor alpha (TNF-alpha) and nitric oxide (NO) production when these cells are subsequently stimulated with 100 ng/ml of LPS.	Thioglycolates	14-28	tumor necrosis factor	Mus musculus	244-253
8426119-1	1993	Preculture of thioglycollate-elicited C3HeB/FeJ mouse peritoneal macrophages in vitro with subthreshold stimulatory concentrations of lipopolysaccharide (LPS) can induce hyporesponsiveness (desensitization) to both tumor necrosis factor alpha (TNF-alpha) and nitric oxide (NO) production when these cells are subsequently stimulated with 100 ng/ml of LPS.	Thioglycolates	14-28	toll-like receptor 4	Mus musculus	351-354
1402389-5	1992	pHi regulation was evaluated as the ability of thioglycolate-elicited murine peritoneal m phi s to recover from an imposed cytoplasmic acid load.	Thioglycolates	47-60	glucose-6-phosphate isomerase 1	Mus musculus	0-3
1431106-3	1992	ANA-1 macrophages and normal thioglycollate-elicited mouse peritoneal macrophages produced little or no detectable nitrite (NO2-) after incubation with IFN-gamma alone or IL-2 alone; however, IL-2 synergized with IFN-gamma for the production of NO2-.	Thioglycolates	29-43	interleukin 2	Mus musculus	171-175
1402389-5	1992	pHi regulation was evaluated as the ability of thioglycolate-elicited murine peritoneal m phi s to recover from an imposed cytoplasmic acid load.	Thioglycolates	47-60	glucose-6-phosphate isomerase 1	Mus musculus	90-93
1402390-1	1992	Thioglycollate (TG)-elicited peritoneal macrophages (m phi s) were highly proliferative and formed m phi colonies in vitro in the presence of m phi colony-stimulating factor (M-CSF), while resident peritoneal m phi s did not.	Thioglycolates	0-14	colony stimulating factor 1 (macrophage)	Mus musculus	142-173
1402390-1	1992	Thioglycollate (TG)-elicited peritoneal macrophages (m phi s) were highly proliferative and formed m phi colonies in vitro in the presence of m phi colony-stimulating factor (M-CSF), while resident peritoneal m phi s did not.	Thioglycolates	0-14	colony stimulating factor 1 (macrophage)	Mus musculus	175-180
1402390-1	1992	Thioglycollate (TG)-elicited peritoneal macrophages (m phi s) were highly proliferative and formed m phi colonies in vitro in the presence of m phi colony-stimulating factor (M-CSF), while resident peritoneal m phi s did not.	Thioglycolates	16-18	colony stimulating factor 1 (macrophage)	Mus musculus	142-173
1402390-1	1992	Thioglycollate (TG)-elicited peritoneal macrophages (m phi s) were highly proliferative and formed m phi colonies in vitro in the presence of m phi colony-stimulating factor (M-CSF), while resident peritoneal m phi s did not.	Thioglycolates	16-18	colony stimulating factor 1 (macrophage)	Mus musculus	175-180
1638511-3	1992	Thioglycollate-elicited macrophages required only LPS plus IFN-gamma for cytostatic activity which was expressed concomitantly with the release of high levels of TNF, IL-1 and IL-6, whereas C3H/HeJ macrophages produced low levels of monokines and were not cytostatic.	Thioglycolates	0-14	interferon gamma	Mus musculus	59-68
1381743-6	1992	Low responsiveness of BALB/c macrophages to stimuli was not observed with TDM only; activation for tumor cytotoxicity of thioglycolate-elicited macrophages from BALB/c mice required also higher doses of interferon-gamma, and LPS.	Thioglycolates	121-134	interferon gamma	Mus musculus	203-219
1522390-1	1992	Thioglycolate-elicited peritoneal macrophages from normal C57B1/6J mice were examined in vitro for bacterial lipopolysaccharide (LPS)-stimulated interleukin-1 (IL-1), IL-6, and tumor necrosis factor (TNF) production.	Thioglycolates	0-13	interleukin 6	Mus musculus	167-171
1522390-1	1992	Thioglycolate-elicited peritoneal macrophages from normal C57B1/6J mice were examined in vitro for bacterial lipopolysaccharide (LPS)-stimulated interleukin-1 (IL-1), IL-6, and tumor necrosis factor (TNF) production.	Thioglycolates	0-13	tumor necrosis factor	Mus musculus	177-198
1522390-1	1992	Thioglycolate-elicited peritoneal macrophages from normal C57B1/6J mice were examined in vitro for bacterial lipopolysaccharide (LPS)-stimulated interleukin-1 (IL-1), IL-6, and tumor necrosis factor (TNF) production.	Thioglycolates	0-13	tumor necrosis factor	Mus musculus	200-203
1362322-1	1992	Thioglycollate-induced murine C57BL/6 and C3H/HeN peritoneal macrophages synthesized interferon-beta (IFN-beta) in response to exposure to glycoproteins such as horseradish peroxidase (HRP) or mannosyl or fucosyl bovine serum albumin (BSAman of BSAfuc, respectively), but not glucosylated or galactosylated BSA (BSAglu or BSAgal, respectively).	Thioglycolates	0-14	interferon beta 1, fibroblast	Mus musculus	85-100
1362322-1	1992	Thioglycollate-induced murine C57BL/6 and C3H/HeN peritoneal macrophages synthesized interferon-beta (IFN-beta) in response to exposure to glycoproteins such as horseradish peroxidase (HRP) or mannosyl or fucosyl bovine serum albumin (BSAman of BSAfuc, respectively), but not glucosylated or galactosylated BSA (BSAglu or BSAgal, respectively).	Thioglycolates	0-14	interferon beta 1, fibroblast	Mus musculus	102-110
1638511-3	1992	Thioglycollate-elicited macrophages required only LPS plus IFN-gamma for cytostatic activity which was expressed concomitantly with the release of high levels of TNF, IL-1 and IL-6, whereas C3H/HeJ macrophages produced low levels of monokines and were not cytostatic.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	162-165
1638511-3	1992	Thioglycollate-elicited macrophages required only LPS plus IFN-gamma for cytostatic activity which was expressed concomitantly with the release of high levels of TNF, IL-1 and IL-6, whereas C3H/HeJ macrophages produced low levels of monokines and were not cytostatic.	Thioglycolates	0-14	interleukin 1 complex	Mus musculus	167-171
1638511-3	1992	Thioglycollate-elicited macrophages required only LPS plus IFN-gamma for cytostatic activity which was expressed concomitantly with the release of high levels of TNF, IL-1 and IL-6, whereas C3H/HeJ macrophages produced low levels of monokines and were not cytostatic.	Thioglycolates	0-14	interleukin 6	Mus musculus	176-180
1573267-7	1992	Thioglycollate-elicited peritoneal exudate macrophages incubated with native doublet MIP 1-secreted bioactive TNF and IL-6, as well as immunoreactive IL-1 alpha, and these effects were enhanced significantly when the cells were costimulated with IFN-gamma.	Thioglycolates	0-14	transportin 1	Homo sapiens	85-90
1314222-3	1992	A 24-h pretreatment of murine thioglycolate-elicited macrophages with LPS resulted in an enhanced ability of these cells to inhibit the intracellular growth of L. pneumophila.	Thioglycolates	30-43	toll-like receptor 4	Mus musculus	70-73
1573267-7	1992	Thioglycollate-elicited peritoneal exudate macrophages incubated with native doublet MIP 1-secreted bioactive TNF and IL-6, as well as immunoreactive IL-1 alpha, and these effects were enhanced significantly when the cells were costimulated with IFN-gamma.	Thioglycolates	0-14	tumor necrosis factor	Homo sapiens	110-113
1573267-7	1992	Thioglycollate-elicited peritoneal exudate macrophages incubated with native doublet MIP 1-secreted bioactive TNF and IL-6, as well as immunoreactive IL-1 alpha, and these effects were enhanced significantly when the cells were costimulated with IFN-gamma.	Thioglycolates	0-14	interleukin 6	Homo sapiens	118-122
1573267-7	1992	Thioglycollate-elicited peritoneal exudate macrophages incubated with native doublet MIP 1-secreted bioactive TNF and IL-6, as well as immunoreactive IL-1 alpha, and these effects were enhanced significantly when the cells were costimulated with IFN-gamma.	Thioglycolates	0-14	interleukin 1 alpha	Homo sapiens	150-160
1573267-7	1992	Thioglycollate-elicited peritoneal exudate macrophages incubated with native doublet MIP 1-secreted bioactive TNF and IL-6, as well as immunoreactive IL-1 alpha, and these effects were enhanced significantly when the cells were costimulated with IFN-gamma.	Thioglycolates	0-14	interferon gamma	Homo sapiens	246-255
1611281-4	1992	CK-M stimulated thioglycollate-induced peritoneal macrophages to produce interleukin 1 (IL-1) and tumor necrosis factor alpha (TNF-alpha) at concentrations of 1-100 ng/ml, and it also induced IL-2 and interferon-gamma (IFN-gamma) as well as IL-6 production by splenocytes.	Thioglycolates	16-30	creatine kinase, muscle	Mus musculus	0-4
1373330-9	1992	In addition, using thioglycollate-induced peritoneal inflammatory exudates, we showed that MRP8 and MRP14 proteins are highly expressed in recruited neutrophils and monocytes.	Thioglycolates	19-33	S100 calcium binding protein A8 (calgranulin A)	Mus musculus	91-95
1373330-9	1992	In addition, using thioglycollate-induced peritoneal inflammatory exudates, we showed that MRP8 and MRP14 proteins are highly expressed in recruited neutrophils and monocytes.	Thioglycolates	19-33	S100 calcium binding protein A9 (calgranulin B)	Mus musculus	100-105
1544928-14	1992	Additionally, although alpha 1,3-GT levels increased upon thioglycollate-induced activation of mouse peritoneal macrophages, the ratio of the alpha 1,3-GT isoforms was essentially unchanged.	Thioglycolates	58-72	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Bos taurus	23-35
1730873-4	1992	In this study, the regulation of ICSBP mRNA induction by IFN-gamma was characterized in murine thioglycolate-elicited peritoneal macrophages.	Thioglycolates	95-108	interferon regulatory factor 8	Mus musculus	33-38
1730873-4	1992	In this study, the regulation of ICSBP mRNA induction by IFN-gamma was characterized in murine thioglycolate-elicited peritoneal macrophages.	Thioglycolates	95-108	interferon gamma	Mus musculus	57-66
1431555-2	1992	The effect of heat shock (HS) on the synthesis of the monokines tumor necrosis factor (TNF) and interleukin 1 (IL-1) by endotoxin-stimulated thioglycollate-elicited peritoneal macrophages was investigated.	Thioglycolates	141-155	tumor necrosis factor	Mus musculus	64-85
1431555-2	1992	The effect of heat shock (HS) on the synthesis of the monokines tumor necrosis factor (TNF) and interleukin 1 (IL-1) by endotoxin-stimulated thioglycollate-elicited peritoneal macrophages was investigated.	Thioglycolates	141-155	tumor necrosis factor	Mus musculus	87-90
1431555-2	1992	The effect of heat shock (HS) on the synthesis of the monokines tumor necrosis factor (TNF) and interleukin 1 (IL-1) by endotoxin-stimulated thioglycollate-elicited peritoneal macrophages was investigated.	Thioglycolates	141-155	interleukin 1 complex	Mus musculus	96-115
1611281-4	1992	CK-M stimulated thioglycollate-induced peritoneal macrophages to produce interleukin 1 (IL-1) and tumor necrosis factor alpha (TNF-alpha) at concentrations of 1-100 ng/ml, and it also induced IL-2 and interferon-gamma (IFN-gamma) as well as IL-6 production by splenocytes.	Thioglycolates	16-30	tumor necrosis factor	Mus musculus	127-136
1611281-4	1992	CK-M stimulated thioglycollate-induced peritoneal macrophages to produce interleukin 1 (IL-1) and tumor necrosis factor alpha (TNF-alpha) at concentrations of 1-100 ng/ml, and it also induced IL-2 and interferon-gamma (IFN-gamma) as well as IL-6 production by splenocytes.	Thioglycolates	16-30	interleukin 2	Mus musculus	192-196
1611281-4	1992	CK-M stimulated thioglycollate-induced peritoneal macrophages to produce interleukin 1 (IL-1) and tumor necrosis factor alpha (TNF-alpha) at concentrations of 1-100 ng/ml, and it also induced IL-2 and interferon-gamma (IFN-gamma) as well as IL-6 production by splenocytes.	Thioglycolates	16-30	interferon gamma	Mus musculus	219-228
1944288-4	1991	The NaF-sensitive alpha-NBE induced in c-fgr transfectants was shown by isoelectric focusing to have a pI of 5.2 to 5.4, a range which was the same as those for thioglycolate-induced murine peritoneal macrophages and 1 alpha,25-dihydroxyvitamin D3-treated WEHI-3B cells.	Thioglycolates	161-174	fibroblast growth factor receptor 1	Mus musculus	39-44
1753106-3	1991	Two cDNA clones, mag-1 and mag-2 (for macrophage-activation gene-1 and -2), were induced by IFN-gamma treatment in both RAW 264.7 cells and thioglycolate-elicited peritoneal macrophages, but not in the noncytolytic cell line, WEHI-3.	Thioglycolates	140-153	guanylate binding protein 2b	Mus musculus	17-22
1753106-3	1991	Two cDNA clones, mag-1 and mag-2 (for macrophage-activation gene-1 and -2), were induced by IFN-gamma treatment in both RAW 264.7 cells and thioglycolate-elicited peritoneal macrophages, but not in the noncytolytic cell line, WEHI-3.	Thioglycolates	140-153	anterior gradient 2	Mus musculus	27-32
1753106-3	1991	Two cDNA clones, mag-1 and mag-2 (for macrophage-activation gene-1 and -2), were induced by IFN-gamma treatment in both RAW 264.7 cells and thioglycolate-elicited peritoneal macrophages, but not in the noncytolytic cell line, WEHI-3.	Thioglycolates	140-153	interferon gamma	Mus musculus	92-101
1940613-1	1991	Recent studies by these investigators have shown that horseradish peroxidase (HRP) can cause murine thioglycollate-induced peritoneal macrophages (M phi) to produce both tumor necrosis factor (TNF) and enhance macrophage-mediated cytotoxicity (MMC) to 3T12 target cells.	Thioglycolates	100-114	tumor necrosis factor	Mus musculus	170-191
1940613-1	1991	Recent studies by these investigators have shown that horseradish peroxidase (HRP) can cause murine thioglycollate-induced peritoneal macrophages (M phi) to produce both tumor necrosis factor (TNF) and enhance macrophage-mediated cytotoxicity (MMC) to 3T12 target cells.	Thioglycolates	100-114	tumor necrosis factor	Mus musculus	193-196
1934597-4	1991	Actinomycin D directly induced procoagulant on the malignant monocytoid cell line WEHI 265, and synergized with LPS to enhance MPCA on both WEHI 265 cells and thioglycollate-induced peritoneal exudate macrophages.	Thioglycolates	159-173	toll-like receptor 4	Mus musculus	112-115
1762301-6	1991	When thioglycollate-elicited peritoneal macrophages (M phi) from normal rats were incubated with these GBM materials, GBM from DM group induced significantly greater levels of TNF and IL-1 production than did GBM from other three groups with at doses of 2.5 to 10 mg.	Thioglycolates	5-19	tumor necrosis factor-like	Rattus norvegicus	176-179
1674521-12	1991	In addition, direct injection of TGF-beta into MRL/n mice also reduces the percentage and number of PMN in the thioglycollate-stimulated peritoneal exudates of these mice.	Thioglycolates	111-125	transforming growth factor, beta 1	Mus musculus	33-41
1658185-3	1991	Since each of these products could potentially inhibit vacuolar-type H+ ATPases, we investigated the effect of L-arginine metabolism on Mo pHi regulation in thioglycolate-elicited murine peritoneal Mos.	Thioglycolates	157-170	glucose-6-phosphate isomerase 1	Mus musculus	139-142
1791140-3	1991	Thioglycollate-elicited macrophages obtained from DMN-exposed animals displayed enhanced levels of constitutively expressed TNF-alpha transcripts compared to vehicle controls.	Thioglycolates	0-14	tumor necrosis factor	Mus musculus	124-133
1901891-3	1991	administration of IFN-gamma (10,000 U/mouse) strongly induced expression of IP-10 mRNA in the adherent cell population of the spleen, thioglycollate-elicited peritoneal macrophages were essentially unresponsive at the same dose.	Thioglycolates	134-148	interferon gamma	Mus musculus	18-27
1901891-11	1991	This differential expression of IP-10 was a consequence of different concentration requirements for IFN-gamma in the two cell types; thioglycollate-elicited macrophages required five- to 10-fold more IFN-gamma than did resident cells to achieve comparable IP-10 mRNA levels whether the agent was provided in vitro or in vivo.	Thioglycolates	133-147	chemokine (C-X-C motif) ligand 10	Mus musculus	32-37
1901891-11	1991	This differential expression of IP-10 was a consequence of different concentration requirements for IFN-gamma in the two cell types; thioglycollate-elicited macrophages required five- to 10-fold more IFN-gamma than did resident cells to achieve comparable IP-10 mRNA levels whether the agent was provided in vitro or in vivo.	Thioglycolates	133-147	interferon gamma	Mus musculus	100-109
1901891-11	1991	This differential expression of IP-10 was a consequence of different concentration requirements for IFN-gamma in the two cell types; thioglycollate-elicited macrophages required five- to 10-fold more IFN-gamma than did resident cells to achieve comparable IP-10 mRNA levels whether the agent was provided in vitro or in vivo.	Thioglycolates	133-147	interferon gamma	Mus musculus	200-209
1869287-4	1991	Listeria- or thioglycollate-induced macrophages from CBA/H (H-2k) mice, when treated with heat-killed Listeria in vitro for 1 h to maintain or increase, respectively, MHC Class II levels before the addition of alloreactive Iak-specific T cells caused inverse dose-responses; the highest T cell proliferation occurred at a stimulator to responder (S : R) ratio of 0.25 and profound suppression at a S : R ratio of 1 or 2.	Thioglycolates	13-27	aurora kinase A	Mus musculus	223-226
2001605-3	1991	Oral administration of levamisole (3 mg/kg) to mice also resulted in potentiation of in vitro IL-1 production by thioglycollate-elicited peritoneal macrophages in response to in vitro LPS stimulation.	Thioglycolates	113-127	interleukin 1 complex	Mus musculus	94-98
1705116-2	1991	Thioglycollate reacts with the 5" product of AP lyase activity on apurinic/apyrimidinic (AP) sites in DNA.	Thioglycolates	0-14	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	45-53
1999225-4	1991	Resident peritoneal M phi (RPM phi) released a small amount of TNF in response to LPS whereas thioglycollate-elicited M phi (TPM phi) released high levels of TNF (5000 U/3 x 10(5) M phi/ml).	Thioglycolates	94-108	tumor necrosis factor	Mus musculus	158-161
1901949-1	1991	Cultured mouse thioglycolate-elicited peritoneal macrophages exhibit a strong block to transcriptional elongation beyond the end of the c-fos gene first exon.	Thioglycolates	15-28	FBJ osteosarcoma oncogene	Mus musculus	136-141
1898614-9	1991	These results suggest that although thioglycolate-induced exudate macrophages from A/J mice support the growth of Lp, these cells readily respond to the activating influence of interferon-gamma.	Thioglycolates	36-49	interferon gamma	Mus musculus	177-193
2209722-7	1990	Parallel in vivo experiments showed that treatment with thioglycollate caused the percentage of lamin A/C-positive peritoneal macrophages to increase from 5 to 80% between Days 0 and 6.	Thioglycolates	56-70	lamin A/C	Homo sapiens	96-101
2170030-3	1990	Thioglycolate elicited peritoneal macrophages were readily activated to significantly increased levels of intracellular TNF, as early as 1 hr after activation with lypopolysaccharide (LPS) + interferon-gamma: maximum intracellular TNF was evident after 2-3 hr.	Thioglycolates	0-13	tumor necrosis factor	Homo sapiens	120-123
2170030-3	1990	Thioglycolate elicited peritoneal macrophages were readily activated to significantly increased levels of intracellular TNF, as early as 1 hr after activation with lypopolysaccharide (LPS) + interferon-gamma: maximum intracellular TNF was evident after 2-3 hr.	Thioglycolates	0-13	interferon gamma	Homo sapiens	191-207
2170030-3	1990	Thioglycolate elicited peritoneal macrophages were readily activated to significantly increased levels of intracellular TNF, as early as 1 hr after activation with lypopolysaccharide (LPS) + interferon-gamma: maximum intracellular TNF was evident after 2-3 hr.	Thioglycolates	0-13	tumor necrosis factor	Homo sapiens	231-234
2222448-0	1990	Enhanced leukotriene C4 synthase activity in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	45-59	leukotriene C4 synthase	Rattus norvegicus	9-32
2119790-4	1990	IFN-gamma-induced neutrophil migration was enhanced when the macrophage population of the peritoneal cavities was increased by previous injection of thioglycollate and reduced by peritoneal lavage.	Thioglycolates	149-163	interferon gamma	Homo sapiens	0-9
9201266-1	1997	Our previous studies demonstrated that both in vivo and in vitro 3,4-dichloro-propionanilide (propanil) exposure inhibited interleukin-6 (IL-6) and tumor necrosis factor (TNF) production by adherent thioglycollate-elicited peritoneal cells (macrophages) after lipopolysaccharide (LPS) stimulation.	Thioglycolates	199-213	interleukin 6	Homo sapiens	138-142
2118559-6	1990	Thioglycolate-elicited peritoneal macrophages contained similar levels of xanthine oxidase activity (265 +/- 42 microIU/10(6) cells).	Thioglycolates	0-13	xanthine dehydrogenase	Mus musculus	74-90
1694517-2	1990	When these erythrocytes (E) were treated with a subagglutinanting dose of alpha 2M, they were adhered to and phagocytosed by thioglycollate-elicited and BCG-activated mouse peritoneal macrophages.	Thioglycolates	125-139	PZP, alpha-2-macroglobulin like	Mus musculus	74-82
2133278-9	1990	We conclude that GM-CSF does not impair, but rather enhances, the ability of circulating neutrophils to respond to thioglycollate-induced inflammation in vivo.	Thioglycolates	115-129	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	17-23
2116476-5	1990	Our study shows that TNF can have opposite effects on Ia expression (induced by IFN-gamma) on thioglycollate-elicited peritoneal macrophages, depending on the length of time cells are treated and on the presence of other modulators.	Thioglycolates	94-108	tumor necrosis factor	Mus musculus	21-24
2116476-5	1990	Our study shows that TNF can have opposite effects on Ia expression (induced by IFN-gamma) on thioglycollate-elicited peritoneal macrophages, depending on the length of time cells are treated and on the presence of other modulators.	Thioglycolates	94-108	interferon gamma	Mus musculus	80-89
2115065-2	1990	When LPL was collected from thioglycollate-elicited peritoneal macrophages (Tg-Mo) or J774.1 cells over a 4 h period in Ca2+ and Mg2(+)-free Dulbecco"s modified Eagle"s medium (d-DMEM) the activity in the collection medium was reduced by 40-62% and 23%, respectively, as compared to that expressed in full medium (DMEM).	Thioglycolates	28-42	lipoprotein lipase	Mus musculus	5-8
1693640-7	1990	High levels of Fc gamma RII alpha were observed in resident and thioglycollate-elicited peritoneal macrophages, but no Fc gamma RII alpha was detected in Bacillus Calmette Guerin-elicited macrophages.	Thioglycolates	64-78	Fc receptor, IgG, low affinity IIb	Mus musculus	15-27
2294153-2	1990	Phorbol myristate acetate (TPA) had an augmenting effect on LPL secretion by in vitro-derived bone marrow macrophages (BMMs), thioglycollate-elicited peritoneal macrophages (TgM phi), and resistant macrophages.	Thioglycolates	126-140	lipoprotein lipase	Mus musculus	60-63
34311083-4	2021	Similarly, thioglycollate-elicited peritoneal cells isolated from wildtype mice treated with TP-064 showed lowered mRNA expression levels and cytokine production of pro-inflammatory mediators interleukin (IL)-1beta, IL-6, IL-12p40, and tumor necrosis factor-alpha in response to lipopolysaccharide exposure.	Thioglycolates	11-25	interleukin 1 alpha	Mus musculus	192-214
34311083-4	2021	Similarly, thioglycollate-elicited peritoneal cells isolated from wildtype mice treated with TP-064 showed lowered mRNA expression levels and cytokine production of pro-inflammatory mediators interleukin (IL)-1beta, IL-6, IL-12p40, and tumor necrosis factor-alpha in response to lipopolysaccharide exposure.	Thioglycolates	11-25	interleukin 6	Mus musculus	216-220
34311083-4	2021	Similarly, thioglycollate-elicited peritoneal cells isolated from wildtype mice treated with TP-064 showed lowered mRNA expression levels and cytokine production of pro-inflammatory mediators interleukin (IL)-1beta, IL-6, IL-12p40, and tumor necrosis factor-alpha in response to lipopolysaccharide exposure.	Thioglycolates	11-25	interleukin 12b	Mus musculus	222-230
34311083-4	2021	Similarly, thioglycollate-elicited peritoneal cells isolated from wildtype mice treated with TP-064 showed lowered mRNA expression levels and cytokine production of pro-inflammatory mediators interleukin (IL)-1beta, IL-6, IL-12p40, and tumor necrosis factor-alpha in response to lipopolysaccharide exposure.	Thioglycolates	11-25	tumor necrosis factor	Mus musculus	236-263
34311083-5	2021	However, TP-064-treated mice exhibited an ongoing pro-inflammatory peritonitis after 5 days of thioglycollate exposure, as evident from a shift in the peritoneal macrophage polarization state from an anti-inflammatory LY6ClowCD206hi to a pro-inflammatory LY6ChiCD206low phenotype.	Thioglycolates	95-109	lymphocyte antigen 6 complex, locus C1	Mus musculus	218-232
34423778-0	2021	Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages.	Thioglycolates	88-102	microRNA 146b	Mus musculus	8-15
34470853-4	2021	The anti-mCRP mAb suppressed leukocyte infiltration in thioglycollate-induced peritonitis, attenuated rheumatoid arthritis symptoms in collagen Ab-induced arthritis model mice, and attenuated lupus nephritis symptoms in MRL/Mp-lpr/lpr lupus-prone model mice.	Thioglycolates	55-69	C-reactive protein, pentraxin-related	Mus musculus	9-13
34459250-9	2021	In additional experiments, interleukin-19 treatment inhibited murine macrophage recruitment following intraperitoneal thioglycolate injection.	Thioglycolates	118-131	interleukin 19	Mus musculus	27-41
34423778-3	2021	Using an unbiased RNA-seq approach, we identified Mir146b as a microRNA whose expression progressively and unidirectionally declined with age in thioglycollate-elicited murine macrophages.	Thioglycolates	145-159	microRNA 146b	Mus musculus	50-57