PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
15586663-4	2004	The purpose of this study was to determine the effects of three routinely used organic solvents (ethanol, methanol, and dimethyl sulfoxide (DMSO)) on the activity of purified PARP-1.	Methanol	106-114	poly(ADP-ribose) polymerase 1	Homo sapiens	175-181
15586663-6	2004	A 112% and 82% increase in PARP-1 activity was observed with 15% ethanol and 20% methanol, respectively.	Methanol	81-89	poly(ADP-ribose) polymerase 1	Homo sapiens	27-33
15003618-3	2004	Methanol fixation shows diffuse staining of Fas and FasL in the cytoplasm, as well as in the nucleus.	Methanol	0-8	Fas ligand	Rattus norvegicus	52-56
16088216-7	2004	rPLF was exported into the culture supernatant at approximately 87 mg/l and a large portion of rPLF was accumulated in the cell cytoplasm at approximately 760 mg/l after 72 h of methanol induction.	Methanol	178-186	periostin	Rattus norvegicus	95-99
15103076-3	2004	We describe plasmid construction and protein expression procedures for producing Drosophila ADAR in this system.ADAR expression in Pichia pastoris uses the methanol-inducible alcohol oxidase AOX1 promoter for induction.	Methanol	156-164	Adenosine deaminase acting on RNA	Drosophila melanogaster	92-96
15103076-3	2004	We describe plasmid construction and protein expression procedures for producing Drosophila ADAR in this system.ADAR expression in Pichia pastoris uses the methanol-inducible alcohol oxidase AOX1 promoter for induction.	Methanol	156-164	Adenosine deaminase acting on RNA	Drosophila melanogaster	112-116
14679220-0	2004	Multiple formate dehydrogenase enzymes in the facultative methylotroph Methylobacterium extorquens AM1 are dispensable for growth on methanol.	Methanol	133-141	MEXAM1_RS21720	Methylobacterium extorquens AM1	17-30
14645999-5	2003	By the uncoupled feeding of glycerol and methanol the volumetric productivity of hEGF increased from 6.4 to 8.0 mg/(L.h), compared with methanol-only feeding.	Methanol	41-49	epidermal growth factor	Homo sapiens	81-85
14974442-1	2004	A methanol extract of chaste-tree berry (Vitex agnus-castus L.) was tested for its ability to displace radiolabeled estradiol from the binding site of estrogen receptors alpha (ERalpha) and beta (ERbeta).	Methanol	2-10	estrogen receptor 1	Homo sapiens	177-184
12962538-3	2003	After 24 h of methanol induction, Northern and Western blotting analyses indicated the expression of JEN1 in the transformants.	Methanol	14-22	Jen1p	Saccharomyces cerevisiae S288C	101-105
14632497-5	2003	In contrast, treatment of [Fe(6)O(2)(OH)(2)(O(2)CBu(t))(10)(hep)(2)] with MeOH leads to the formation of [Fe(10)(OMe)(20)(O(2)CBu(t))(10)] (4), which exhibits the more common type of ferric wheel seen in analogous complexes with other carboxylate groups.	Methanol	74-78	EPH receptor B6	Homo sapiens	60-63
14683215-2	2003	Probing the hydroxyl stretch of methanol-OD oligomers in CCl4, the dynamics of the evolving hydrogen bonded network are measured with ultrashort (<50 fs) pulses.	Methanol	32-40	C-C motif chemokine ligand 4	Homo sapiens	57-61
14645999-5	2003	By the uncoupled feeding of glycerol and methanol the volumetric productivity of hEGF increased from 6.4 to 8.0 mg/(L.h), compared with methanol-only feeding.	Methanol	136-144	epidermal growth factor	Homo sapiens	81-85
14505311-7	2003	RESULTS: Fixing cells with 1.5% formaldehyde followed by permeabilization in methanol gave optimal results for pERK, pp38, pJNK, pStat1, pStat5, and pStat6 staining.	Methanol	77-85	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	111-115
14534783-1	2003	The FDH1 gene of Candida boidinii encodes an NAD+-dependent formate dehydrogenase, which catalyzes the last reaction in the methanol dissimilation pathway.	Methanol	124-132	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	4-8
14534783-2	2003	FDH1 expression is strongly induced by methanol, as are the promoters of the genes AOD1 (alcohol oxidase) and DAS1 (dihydroxyacetone synthase).	Methanol	39-47	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	0-4
14534783-5	2003	Both elements were necessary for full induction of the FDH1 promoter by methanol, while only the UAS-FM element was required for full induction by formate.	Methanol	72-80	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	55-59
15348529-5	2003	The alteration of surface plasticizer level was achieved by a methanol-cleaning treatment with a variety of cleaning times and the fibrinogen adsorption on plasticized PVC decreases with the reduction of surface plasticizer level.	Methanol	62-70	fibrinogen beta chain	Homo sapiens	131-141
14604466-2	2003	The possibility of cytochrome p450 (CYP) induction by bupropion (10 microM) was evaluated in-vitro by comparing catalytic activity, immunoreactive protein and CYP mRNA levels from human hepatocytes in primary culture versus cells treated with vehicle (0.5% methanol) and with rifampicin (rifampin) as a positive control.	Methanol	257-265	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	19-34
12971758-9	2003	The reaction of U(III) with methanol in the presence of the supporting ligand tpa leads to formation of alkoxo complexes similarly to what is found for amide or cyclopentadienyl derivatives.	Methanol	28-36	plasminogen activator, tissue type	Homo sapiens	78-81
12971758-12	2003	The reaction of [U(tpa)(2)]I(3) with 2 equiv of methanol in acetonitrile allows the isolation of the bismethoxo complex of U(IV) [U(tpa)I(2)(OMe)(2)], 5, in 35-47% yield, which has been fully characterized.	Methanol	48-56	plasminogen activator, tissue type	Homo sapiens	19-22
12971758-12	2003	The reaction of [U(tpa)(2)]I(3) with 2 equiv of methanol in acetonitrile allows the isolation of the bismethoxo complex of U(IV) [U(tpa)I(2)(OMe)(2)], 5, in 35-47% yield, which has been fully characterized.	Methanol	48-56	plasminogen activator, tissue type	Homo sapiens	132-135
12968891-7	2003	Syn-hh photodimers of 6-methylcoumarin can be photochemically split into the monomers; they partly proved thermally unstable against acids, bases, methanol, and on SiO(2) surfaces.	Methanol	147-155	synemin	Homo sapiens	0-3
14550639-2	2003	We adopted a simple and quick procedure to generate an expression cassette by constructing a donor vector harboring proNsCys followed by recombination with an acceptor vector in a way so that the proNsCys gene was placed downstream of the methanol-inducible AOX1 promoter and alpha-mating factor signal sequence gene.	Methanol	239-247	aldehyde oxidase 1	Homo sapiens	258-262
14604466-2	2003	The possibility of cytochrome p450 (CYP) induction by bupropion (10 microM) was evaluated in-vitro by comparing catalytic activity, immunoreactive protein and CYP mRNA levels from human hepatocytes in primary culture versus cells treated with vehicle (0.5% methanol) and with rifampicin (rifampin) as a positive control.	Methanol	257-265	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	36-39
12895037-3	2003	The coupling of building blocks 15 and 36e in the presence of MgBr(2).OEt(2) at 0 degrees C proceeds with an exo stereoselectivity (3.2:1) considerably more advantageous for the acquisition of carbinol 37e than in the absence of the additive (exo/endo = 1:5.7).	Methanol	193-201	ENDO1	Homo sapiens	247-255
15969091-8	2003	After 0.5% methanol induction, SDS-PAGE analysis of the culture supernatant indicated that the yield of recombinant cystatin was about 215mg x L(-1) with the percentage about 73.6%.	Methanol	11-19	LOC100857070	Zea mays	116-124
12885518-3	2003	On a Kromasil-C(18) column, with methanol-water (80/20 v/v) as the mobile phase, the best single-solute adsorption isotherm of both toluene and ethylbenzene is the liquid-solid extended multilayer BET isotherm.	Methanol	33-41	delta/notch like EGF repeat containing	Homo sapiens	197-200
12924560-7	2003	The best multivariate relationships useful in predicting the pharmacological activity of thiazole and benzothiazole derivatives were obtained under the condition of experiment with RP2 TLC plates using the developing solvent acetonitrile-methanol-buffer (40:40:20, v/v).	Methanol	238-246	RP2 activator of ARL3 GTPase	Homo sapiens	181-184
12904537-1	2003	The methylotrophic yeast Candida boidinii exhibits S-formylglutathione hydrolase activity (FGH, EC 3.1.2.12), which is involved in the glutathione-dependent formaldehyde oxidation pathway during growth on methanol as the sole carbon source.	Methanol	205-213	S-formylglutathione hydrolase	Saccharomyces cerevisiae S288C	51-80
12897974-2	2003	The recombinant plasmid pHIL-K1-5 was transformed into Pichia pastoris GS115 and the recombinant yeast was induced by methanol to express the recombinant protein.	Methanol	118-126	RBPJ pseudogene 3	Homo sapiens	29-33
12842345-3	2003	In this work, we compared the chemical stability of tretinoin (TRA) in methanol and in vesicular suspensions exposed both to UV and artificial daylight conditions with the aim of evaluating the potential of niosomes as topical carriers capable of improving the stability of photosensitive drugs.	Methanol	71-79	T cell receptor alpha locus	Homo sapiens	63-66
12842345-7	2003	After UV irradiation, TRA dissolved in methanol degraded very quickly while the incorporation in vesicles always led to a reduction of the photodegradation process.	Methanol	39-47	T cell receptor alpha locus	Homo sapiens	22-25
12898421-1	2003	In the course of screening inhibitors from the methanol (MeOH) extracts of 168 medicinal plants against lymphocyte cell-specific kinase (Lck) Src -homology 2 (SH2) binding to a synthetic phosphotyrosine-containing peptide (phosphopeptide), we isolated rosmarinic acid from the MeOH extract of Prunella vulgaris, which showed specific inhibitory activity.	Methanol	47-55	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	137-140
12826258-2	2003	We demonstrate that DNR, DXR, and 5IDNR undergo irreversible oxidation by MP11/H(2)O(2), forming colorless products in both phosphate buffer pH 7.0 and in phosphate buffer pH 7.0/MeOH mixture (1:1 vol/vol), suggesting an extensive modification of the compounds" chromophores.	Methanol	179-183	non-compact myelin associated protein	Homo sapiens	74-78
12821316-5	2003	SDS-PAGE and Western blot assays of culture broth from a methanol-induced expression strain demonstrated that recombinant hNTN, a 16kDa glycosylated protein, was secreted into the culture medium.	Methanol	57-65	neurturin	Homo sapiens	122-126
12820122-4	2003	METHODS: After immunostaining of fresh samples of peripheral blood, bone marrow and single cell suspensions of lymph nodes from healthy and lymphoma patients, a methanol fixation for TO-PRO-3 and DRAQ5 staining was tested.	Methanol	161-169	pyrroline-5-carboxylate reductase 1	Homo sapiens	186-191
12898427-5	2003	The aqueous and methanol crude extracts exhibited dose-dependent inhibitory activity on 125I-TGF-beta1 binding to its receptor in Balb/c 3T3 cells.	Methanol	16-24	transforming growth factor, beta 1	Mus musculus	93-102
12898421-1	2003	In the course of screening inhibitors from the methanol (MeOH) extracts of 168 medicinal plants against lymphocyte cell-specific kinase (Lck) Src -homology 2 (SH2) binding to a synthetic phosphotyrosine-containing peptide (phosphopeptide), we isolated rosmarinic acid from the MeOH extract of Prunella vulgaris, which showed specific inhibitory activity.	Methanol	57-61	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	137-140
12898421-1	2003	In the course of screening inhibitors from the methanol (MeOH) extracts of 168 medicinal plants against lymphocyte cell-specific kinase (Lck) Src -homology 2 (SH2) binding to a synthetic phosphotyrosine-containing peptide (phosphopeptide), we isolated rosmarinic acid from the MeOH extract of Prunella vulgaris, which showed specific inhibitory activity.	Methanol	277-281	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	137-140
12632400-0	2003	Effect of methanol feeding strategies on production and yield of recombinant mouse endostatin from Pichia pastoris.	Methanol	10-18	collagen, type XVIII, alpha 1	Mus musculus	83-93
12754286-2	2003	In addition, catalase can oxidize, by means of its peroxidatic activity, a variety of substrates such as methanol and ethanol, producing the corresponding aldehydes.	Methanol	105-113	catalase	Rattus norvegicus	13-21
12744644-0	2003	Preparation of a t,t conjugated linoleic acid methylester (CLA-Me) isomers mixture from synthetic CLA by methylation with BF3/methanol.	Methanol	126-134	selectin P ligand	Homo sapiens	59-62
12744644-0	2003	Preparation of a t,t conjugated linoleic acid methylester (CLA-Me) isomers mixture from synthetic CLA by methylation with BF3/methanol.	Methanol	126-134	selectin P ligand	Homo sapiens	98-101
12831777-0	2003	Methanol extract of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-kappaB activation.	Methanol	0-8	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	107-116
12831777-3	2003	We examined how the methanol extract of C. pruinosa regulates production of IL-1beta, TNF-alpha, nitric oxide (NO), and prostaglandin E(2) (PGE(2)) in vitro and in vivo.	Methanol	20-28	interleukin 1 beta	Mus musculus	76-84
12831777-3	2003	We examined how the methanol extract of C. pruinosa regulates production of IL-1beta, TNF-alpha, nitric oxide (NO), and prostaglandin E(2) (PGE(2)) in vitro and in vivo.	Methanol	20-28	tumor necrosis factor	Mus musculus	86-95
12831777-7	2003	These results suggest that the C. pruinosa methanol extract suppresses inflammation through suppression of NF-kappaB-dependent inflammatory gene expression, suggesting that the C. pruinosa extract may be beneficial for treatment of endotoxin shock or sepsis.	Methanol	43-51	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	107-116
12877557-6	2003	These results suggest that three phospholipid compounds isolated from the methanol extract of Bombycis corpus may exert neurotrophic effects by stimulation of NGF synthesis in astrocytes.	Methanol	74-82	nerve growth factor	Homo sapiens	159-162
12632400-4	2003	Three methanol addition strategies were evaluated for the purpose of optimizing recombinant endostatin production.	Methanol	6-14	collagen, type XVIII, alpha 1	Mus musculus	92-102
12708846-5	2003	The methanol and methane reactions with 1 have large kinetic isotope effects (k(CH3OH)/k(CD3OD) = 9.7 +/- 0.8, k(CH4)/k(CD4) = 10.8 +/- 1.0, T = 296 K), consistent with a rate-limiting step of C-H bond homolysis through a linear transition state.	Methanol	4-12	CD4 molecule	Homo sapiens	120-123
12733932-8	2003	In the CW-EPR spectrum of Cob(II)ester in methanol, a second component appears below 100 K. Different cooling experiments suggest that this observation is related to the phase transition of methanol from the alpha-phase to the glassy state.	Methanol	42-50	metabolism of cobalamin associated B	Homo sapiens	26-29
12733932-8	2003	In the CW-EPR spectrum of Cob(II)ester in methanol, a second component appears below 100 K. Different cooling experiments suggest that this observation is related to the phase transition of methanol from the alpha-phase to the glassy state.	Methanol	190-198	metabolism of cobalamin associated B	Homo sapiens	26-29
12736520-3	2003	at a dose of 200 mg/kg, methanol extracts of Sophora flavescens and Cnidium monnieri, but not the others, significantly inhibited a serotonin (5-HT)-induced itch-related response (scratching) and the spontaneous scratching of NC mice, a mouse model of atopic dermatitis.	Methanol	24-32	itchy, E3 ubiquitin protein ligase	Mus musculus	157-161
12759105-2	2003	Intrinsic differences in the metabolism of CH(3)OH to formaldehyde (HCHO) and formic acid (HCOOH) by the enzymes alcohol dehydrogenase (ADH1), formaldehyde dehydrogenase (ADH3), and catalase may contribute to the observed species sensitivity.	Methanol	43-50	alcohol dehydrogenase 1 (class I)	Mus musculus	136-140
12759105-2	2003	Intrinsic differences in the metabolism of CH(3)OH to formaldehyde (HCHO) and formic acid (HCOOH) by the enzymes alcohol dehydrogenase (ADH1), formaldehyde dehydrogenase (ADH3), and catalase may contribute to the observed species sensitivity.	Methanol	43-50	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	Mus musculus	171-175
12759105-2	2003	Intrinsic differences in the metabolism of CH(3)OH to formaldehyde (HCHO) and formic acid (HCOOH) by the enzymes alcohol dehydrogenase (ADH1), formaldehyde dehydrogenase (ADH3), and catalase may contribute to the observed species sensitivity.	Methanol	43-50	catalase	Mus musculus	182-190
12740845-4	2003	The former transforms into the latter under reflux in methanol in the presence of sodium bromide; this involves the migration of the fac-[Mn(CO)(3)](+) moiety from a basal kappa(2)O coordination site to a lateral kappa(3)O site.	Methanol	54-62	FA complementation group C	Homo sapiens	133-136
12685706-2	2003	A biphasic pattern was observed in the relationship between the log of the carbon-normalized sorption distribution coefficient (Koc) and the volumetric fraction of water-miscible cosolvent (fc), in this case methanol, that was accounted for with phenanthrene solubility data.	Methanol	208-216	insulin like growth factor 2 mRNA binding protein 3	Homo sapiens	128-131
12686102-1	2003	This is a review of recent work on methanol dehydrogenase (MDH), a pyrroloquinoline quinone (PQQ)-containing enzyme catalysing the oxidation of methanol to formaldehyde in methylotrophic bacteria.	Methanol	35-43	malate dehydrogenase 2	Homo sapiens	59-62
12673029-4	2003	Consistent with these observations, the protein and mRNA expression level of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 was inhibited by MeOH extracts of the aerial part of S. chinensis (SCM) in a dose-dependent manner.	Methanol	150-154	nitric oxide synthase 2, inducible	Mus musculus	100-104
12672986-2	2003	The MeOH extract of the fruits of Bupleurum rotundifolium showed inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth (GI(50): 6.25 microg/ml).	Methanol	4-8	potassium voltage-gated channel subfamily A member 1	Homo sapiens	123-127
12722157-1	2003	In order to find novel anti-HIV agents from natural products, 80 MeOH extracts of Korean plants were applied to a syncytia formation inhibition assay, which is based on the interaction between the HIV-1 envelope glycoprotein gp120/41 and the cellular membrane protein CD4 of T lymphocytes.	Methanol	65-69	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	225-233
12639118-2	2003	Addition of aqueous H(2)O(2) to methanol solutions of the Mn(II) complexes of L(1) and L(2) produced green solutions in a fast reaction from which subsequently precipitated brown solids of the dioxo-bridged dinuclear complexes 1 and 2, respectively, which have the general formula [LMn(III)(mu-O)(2)Mn(III)L](ClO(4))(2).	Methanol	32-40	L1 cell adhesion molecule	Homo sapiens	78-82
12639118-2	2003	Addition of aqueous H(2)O(2) to methanol solutions of the Mn(II) complexes of L(1) and L(2) produced green solutions in a fast reaction from which subsequently precipitated brown solids of the dioxo-bridged dinuclear complexes 1 and 2, respectively, which have the general formula [LMn(III)(mu-O)(2)Mn(III)L](ClO(4))(2).	Methanol	32-40	immunoglobulin kappa variable 3-15	Homo sapiens	87-91
12639118-3	2003	Addition of 30% aqueous H(2)O(2) to the methanol solution of the Mn(II) complex of L(3) ([Mn(II)L(3)(CH(3)CN)(H(2)O)](ClO(4))(2) (3)) showed a very sluggish change gradually precipitating an insoluble black gummy solid, but no dioxo-bridged manganese complex is produced.	Methanol	40-48	immunoglobulin kappa variable 2-14 (pseudogene)	Homo sapiens	83-87
12703775-1	2003	High performance (open circuit voltage = 920 mV, maximum power density = 14-15 mW cm(-2)) of the PEM fuel cell was achieved by using cyclohexane as a fuel with zero-CO2 emission and lower-crossover through PEM than with a methanol-based fuel cell.	Methanol	222-230	mucin 1, cell surface associated	Homo sapiens	97-100
16233441-2	2003	Immobilized lipase is frequently deactivated by lower alcohols with deactivation being caused by the immiscibility between triglycerides and methanol or ethanol.	Methanol	141-149	PAN0_003d1715	Moesziomyces antarcticus	12-18
12662212-7	2003	Methanol washing resulted in a significant moderation in CD11b upregulation in both blood types; 117 +/- 27% of baseline in human and 150 +/- 14.7% in rodent.	Methanol	0-8	integrin subunit alpha M	Homo sapiens	57-62
12627436-7	2003	In contrast to aqueous buffers, the separation of Leu- and Met-enkephalin could also be obtained in buffers in methanol at high pH.	Methanol	111-119	proopiomelanocortin	Homo sapiens	59-73
15966315-10	2003	The transformants (His+ Mut(s)) containing multi-copy gene fragment of TRAIL were selected with increasing concentration of G418 and induced with 0.5% methanol in shaking flask to expression the active domain of TRAIL.	Methanol	151-159	TNF superfamily member 10	Homo sapiens	71-76
15966315-10	2003	The transformants (His+ Mut(s)) containing multi-copy gene fragment of TRAIL were selected with increasing concentration of G418 and induced with 0.5% methanol in shaking flask to expression the active domain of TRAIL.	Methanol	151-159	TNF superfamily member 10	Homo sapiens	212-217
12596168-0	2003	Improved methanol-to-olefin catalyst with nanocages functionalized through ship-in-a-bottle synthesis from PH3.	Methanol	9-17	inositol polyphosphate-5-phosphatase D	Homo sapiens	75-79
12568801-6	2003	Although the optimal temperature of LAP activity was 40 degrees C, the enzyme was active over a broad temperature range from 2 to 60 degrees C. Among a number of inhibitors tested, heavy metals and 1,10-phenanthroline completely inhibited the enzyme, while methanol, ethanol and EGTA stimulated somewhat LAP activity.	Methanol	257-265	leucine aminopeptidase 3	Homo sapiens	36-39
12527510-2	2003	METHODS: The recombinant yeast strain containing the gene sequence encoding highly soluble rhES was induced by methanol for rhES production, which was purified with heparin affinity chromatography.	Methanol	111-119	RASD family, member 2	Mus musculus	91-95
12527510-2	2003	METHODS: The recombinant yeast strain containing the gene sequence encoding highly soluble rhES was induced by methanol for rhES production, which was purified with heparin affinity chromatography.	Methanol	111-119	RASD family, member 2	Mus musculus	124-128
12659192-4	2003	Hydrogen/deuterium (H/D) exchange of lysozyme in solution confirms that it is partially unfolded at pH 2.0 in water/methanol (v/v = 2/8).	Methanol	116-124	lysozyme	Homo sapiens	37-45
12659192-5	2003	With electrospray ionization (ESI) mass spectrometry (MS), lysozyme in water produces ions with charges +7 to +12, with the greatest intensity at +10, whereas lysozyme in water/methanol (2/8) produces ions with charges +6 to +12 with the greatest intensity at +7.	Methanol	177-185	lysozyme	Homo sapiens	59-67
12659192-5	2003	With electrospray ionization (ESI) mass spectrometry (MS), lysozyme in water produces ions with charges +7 to +12, with the greatest intensity at +10, whereas lysozyme in water/methanol (2/8) produces ions with charges +6 to +12 with the greatest intensity at +7.	Methanol	177-185	lysozyme	Homo sapiens	159-167
12659192-11	2003	Thus, disulfide-intact gaseous lysozyme ions generated from the denatured state in water/methanol (2/8) refold into compact structures in the gas phase on a time scale of milliseconds or less.	Methanol	89-97	lysozyme	Homo sapiens	31-39
12359718-4	2002	Surprisingly however, Fuc-TIV-generated sLe(x) was resistant to proteinase K and trypsin treatment and could be removed from cells by delipidation with chloroform/methanol, whereas 80-90% of Fuc-TVII-generated sLe(x) was protease-sensitive, and most of it resistant to delipidation.	Methanol	163-171	fucosyltransferase 4	Mus musculus	22-29
15052735-1	2003	In the first pass methanol biotransformation three enzymatic systems: alcohol dehydrogenase (ADH), microsomal alcohol oxidising system (MEOS) linked with cytochrome P-450 and catalase are involved.	Methanol	18-26	aldo-keto reductase family 1 member A1	Rattus norvegicus	70-91
15052735-1	2003	In the first pass methanol biotransformation three enzymatic systems: alcohol dehydrogenase (ADH), microsomal alcohol oxidising system (MEOS) linked with cytochrome P-450 and catalase are involved.	Methanol	18-26	aldo-keto reductase family 1 member A1	Rattus norvegicus	93-96
15052735-1	2003	In the first pass methanol biotransformation three enzymatic systems: alcohol dehydrogenase (ADH), microsomal alcohol oxidising system (MEOS) linked with cytochrome P-450 and catalase are involved.	Methanol	18-26	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	154-183
15052735-3	2003	The aim of this investigation was to check the influence of some effective inhibitors of ADH and MEOS: 4-methylpyrazole, cimetidine, EDTA and 1,10-phenantroline on the activity of catalase with methanol as a substrate and the comparison with 3-amino-1,2,4-triasole.	Methanol	194-202	aldo-keto reductase family 1 member A1	Rattus norvegicus	89-92
15052735-3	2003	The aim of this investigation was to check the influence of some effective inhibitors of ADH and MEOS: 4-methylpyrazole, cimetidine, EDTA and 1,10-phenantroline on the activity of catalase with methanol as a substrate and the comparison with 3-amino-1,2,4-triasole.	Methanol	194-202	catalase	Rattus norvegicus	180-188
12444766-3	2002	RhCl(3) forms, with tpdm in boiling methanol, a 1:1 kinetic mixture of fac- and mer-isomers RhCl(3)(tpdm).	Methanol	36-44	FA complementation group C	Homo sapiens	71-74
12553668-9	2002	In contrast to lamin B1 in normal cells, this cleaved lamin B1, which is apparently still associated with the nuclear membrane, can be completely extracted by methanol or ethanol.	Methanol	159-167	lamin-B1	Cricetulus griseus	54-62
12499594-6	2002	The results show that, in the presence of a small quantity of accessible silanols, the use of 50% aqueous methanol (M50) as eluent yields values of log k directly proportional to log P(oct) in accord with our earlier proposal that use of log k(M50) provides a convenient means for rapid estimation and prediction of log P(oct).	Methanol	106-114	plexin A2	Homo sapiens	185-188
12499594-6	2002	The results show that, in the presence of a small quantity of accessible silanols, the use of 50% aqueous methanol (M50) as eluent yields values of log k directly proportional to log P(oct) in accord with our earlier proposal that use of log k(M50) provides a convenient means for rapid estimation and prediction of log P(oct).	Methanol	106-114	plexin A2	Homo sapiens	322-325
12465028-2	2002	We recently solved the three-dimensional structure of chemically synthesized, unphosphorylated, monomeric PLN (C41F) by high-resolution nuclear magnetic resonance spectroscopy in chloroform/methanol.	Methanol	190-198	phospholamban	Homo sapiens	106-109
12526206-3	2002	The Gsh+ transformants of the gsh1 and gsh2 mutants, which bear plasmids pG1 and pG24 with the 7.2- and 4.3-kbp DNA fragments, respectively, had a completely restored wild-type phenotype with the ability to synthesize GSH and to grow in GSH-deficient synthetic media on various carbon sources, including methanol, and with acquired tolerance to cadmium ions.	Methanol	304-312	glutathione synthase	Saccharomyces cerevisiae S288C	39-43
12526215-4	2002	METHODS: To select a strain that could highly express recombinant human endostatin, then induce the clone to express rhES by adding methanol.	Methanol	132-140	RASD family member 2	Homo sapiens	117-121
12506995-1	2002	A methanol extract of Coptidis Rhizoma effectively enhanced the outgrowth of neurite in PC12 cells induced by nerve growth factor (NGF).	Methanol	2-10	nerve growth factor	Rattus norvegicus	110-129
12506995-1	2002	A methanol extract of Coptidis Rhizoma effectively enhanced the outgrowth of neurite in PC12 cells induced by nerve growth factor (NGF).	Methanol	2-10	nerve growth factor	Rattus norvegicus	131-134
12456098-3	2002	The mobile phase employed was sulphuric acid solution working at a flow-rate of 0.35 ml min(-1) for the whole run, while methanol was linearly increased to 0.45 ml min(-1) from 15 to 75 min followed by a 5-min isocratic elution.	Methanol	121-129	CD59 molecule (CD59 blood group)	Homo sapiens	164-170
12413723-2	2002	In this study, we evaluated approximately 170 methanol extracts of natural products including Korean herbal medicines for the inhibition of prostaglandin E(2) production (for COX-2 inhibitors) and nitric oxide formation (for iNOS inhibitors) in lipopolysaccharide (LPS)-induced mouse macrophages RAW264.7 cells.	Methanol	46-54	cytochrome c oxidase II, mitochondrial	Mus musculus	175-180
12526206-4	2002	In addition, the 4.3-kbp DNA fragment borne by plasmid pG24 eliminated pleiotropic changes in the gsh2 mutants associated with methylotrophic growth in a semisynthetic (GSH-supplemented) medium (poor growth and alterations in the activity of the GSH-catabolizing enzyme gamma-glutamyltransferase and the methanol-oxidizing enzyme alcohol oxidase).	Methanol	304-312	glutathione synthase	Saccharomyces cerevisiae S288C	98-102
12392098-1	2002	The MeOH extract of the roots of Inula helenium showed a high inhibitory activity for cell growth against MK-1, HeLa and B16F10 cell lines.	Methanol	4-8	potassium voltage-gated channel subfamily A member 1	Homo sapiens	106-110
12223239-3	2002	Using the CHCl(3)/MeOH (5:1 v/v) spreading solvent, we found an average molecular area of ZL-DHP of approximately 1200 A(2).	Methanol	18-22	dihydropyrimidinase	Homo sapiens	93-96
12553892-9	2002	CONCLUSIONS: Reliable control of lactase release was achieved by microencapsulating the enzyme with pH-sensitive Eudragit L and S enteric polymers using either acetone- or methanol-based solvent but lactase activity was preserved only in acetone-based formulations.	Methanol	172-180	lactase	Homo sapiens	33-40
12411111-10	2002	Secreted expression of hrHBNF protein in culture medium was obtained when the positive clone containing the HBNF cDNA gene was induced by methanol.	Methanol	138-146	pleiotrophin	Homo sapiens	25-29
12685577-7	2002	A C18 column was chosen to concentrate the mycotoxins, and the analytes were eluted from C18 using methanol.	Methanol	99-107	Bardet-Biedl syndrome 9	Homo sapiens	89-92
12220494-2	2002	GC/MS and NMR analysis of chloroform/methanol extracts from purified HNF4alpha and HNF4gamma LBDs identified mixtures of saturated and cis-monounsaturated C14-18 fatty acids.	Methanol	37-45	hepatocyte nuclear factor 4 alpha	Homo sapiens	69-78
12220494-2	2002	GC/MS and NMR analysis of chloroform/methanol extracts from purified HNF4alpha and HNF4gamma LBDs identified mixtures of saturated and cis-monounsaturated C14-18 fatty acids.	Methanol	37-45	hepatocyte nuclear factor 4 gamma	Homo sapiens	83-92
12665309-6	2002	Further, transient absorption spectra due to T1 (n,pi*) and T2 (pi,pi*) being simultaneously populated are observed upon laser excitation of 4-MBP in polar solvents such as acetonitrile or methanol.	Methanol	189-197	myelin basic protein	Homo sapiens	143-146
12098243-3	2002	Employing samarium(II) iodide and MeOH, functionalized syn-cyclopentanol products are obtained stereoselectively.	Methanol	34-38	synemin	Homo sapiens	55-58
12160395-4	2002	Likewise, addition of an excess of pyridine to 2 in CH(2)Cl(2) followed by slow diffusion of MeOH gives [(TBP)(8)CzCo(III)(py)(2)] (4) as a crystalline solid, which was also characterized by X-ray crystallography.	Methanol	93-97	TATA-box binding protein	Homo sapiens	106-109
12127234-1	2002	A chromogenic bioassay was utilized to determine the antithrombin activity of the methylene chloride and methanol extracts prepared from forty-five plants of Russia.	Methanol	105-113	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	Mus musculus	53-65
12127234-5	2002	The methanol extracts of Quercus robur and Sanguisorba officinalis demonstrated high activity against both thrombin and cancer.	Methanol	4-12	coagulation factor II	Mus musculus	107-115
12137961-6	2002	The ANG II-immunoreactive material was further characterized biochemically by HPLC on a reversed phase C(18) column in an acetonitrile and methanol gradient as Ile(5)-ANG II and ANG II metabolites such as Ile(4)-ANG III, Ile(3)-ANG II(3-8)hexapeptide and Ile(2)-ANG II(4-8)pentapeptide.	Methanol	139-147	angiogenin	Homo sapiens	4-7
12137961-6	2002	The ANG II-immunoreactive material was further characterized biochemically by HPLC on a reversed phase C(18) column in an acetonitrile and methanol gradient as Ile(5)-ANG II and ANG II metabolites such as Ile(4)-ANG III, Ile(3)-ANG II(3-8)hexapeptide and Ile(2)-ANG II(4-8)pentapeptide.	Methanol	139-147	angiotensinogen	Homo sapiens	4-10
12126020-0	2002	Exposure to 200 ppm of methanol increases the concentrations of interleukin-1beta and interleukin-8 in nasal secretions of healthy volunteers.	Methanol	23-31	interleukin 1 beta	Homo sapiens	64-81
12126020-0	2002	Exposure to 200 ppm of methanol increases the concentrations of interleukin-1beta and interleukin-8 in nasal secretions of healthy volunteers.	Methanol	23-31	C-X-C motif chemokine ligand 8	Homo sapiens	86-99
12126020-7	2002	The median concentrations of IL-8 and IL-1beta were significantly elevated after exposure to 200 ppm of methanol as compared to exposure to 20 ppm (IL-1beta, 21.4 versus 8.3 pg/mL, p = .001; IL-8, 424 versus 356 pg/mL, p = .02).	Methanol	104-112	C-X-C motif chemokine ligand 8	Homo sapiens	29-33
12126020-7	2002	The median concentrations of IL-8 and IL-1beta were significantly elevated after exposure to 200 ppm of methanol as compared to exposure to 20 ppm (IL-1beta, 21.4 versus 8.3 pg/mL, p = .001; IL-8, 424 versus 356 pg/mL, p = .02).	Methanol	104-112	interleukin 1 beta	Homo sapiens	38-46
12126020-7	2002	The median concentrations of IL-8 and IL-1beta were significantly elevated after exposure to 200 ppm of methanol as compared to exposure to 20 ppm (IL-1beta, 21.4 versus 8.3 pg/mL, p = .001; IL-8, 424 versus 356 pg/mL, p = .02).	Methanol	104-112	C-X-C motif chemokine ligand 8	Homo sapiens	191-195
12126020-9	2002	Both IL-8 and IL-1beta proved to be sensitive indicators for subclinical irritating effects of methanol in vivo.	Methanol	95-103	C-X-C motif chemokine ligand 8	Homo sapiens	5-9
12126020-9	2002	Both IL-8 and IL-1beta proved to be sensitive indicators for subclinical irritating effects of methanol in vivo.	Methanol	95-103	interleukin 1 beta	Homo sapiens	14-22
12127898-7	2002	An aberrant increase in the expression of Growth-Associated Protein (GAP-43), a neuron-specific growth-associated protein was observed in pups in the FD group exposed to 2% and 4% methanol, while an increase in the expression of GAP-43 in the FS group was found only at 4% methanol exposure in the hippocampal region as compared to their respective controls.	Methanol	180-188	growth associated protein 43	Rattus norvegicus	69-75
12084067-7	2002	Employing NMR spectroscopy we found this part of Vpr to be almost completely alpha helical in the presence of micelles, as well as in trifluoroethanol containing and methanol/chloroform solvent.	Methanol	166-174	Vpr	Human immunodeficiency virus 1	49-52
12127898-7	2002	An aberrant increase in the expression of Growth-Associated Protein (GAP-43), a neuron-specific growth-associated protein was observed in pups in the FD group exposed to 2% and 4% methanol, while an increase in the expression of GAP-43 in the FS group was found only at 4% methanol exposure in the hippocampal region as compared to their respective controls.	Methanol	273-281	growth associated protein 43	Rattus norvegicus	69-75
12112292-1	2002	The cytotoxic activity of methanol extracts of leaves collected from 39 seashore plants in Iriomote Island, subtropical Japan was examined on human leukaemia cells (K562 cells) using a flow cytometer with two fluorescent probes, ethidium bromide and annexin V-FITC.	Methanol	26-34	annexin A5	Homo sapiens	250-259
12109073-3	2002	In the presence of NO, both the reaction temperature and the CH4/O2 ratio affected selectivity to CH3OH and HCHO.	Methanol	98-103	EBP cholestenol delta-isomerase	Homo sapiens	61-67
12083551-4	2002	A flow rate of 1.15 ml min(-1) at a column temperature of 43.5 degrees C using 63.7% methanol in water gave the most efficient separation.	Methanol	85-93	CD59 molecule (CD59 blood group)	Homo sapiens	23-29
12116367-7	2002	RESULTS: Paraformaldehyde-methanol treatment of dendritic cells is a good combination to visualize NF-kappaB translocation by confocal microscopy.	Methanol	26-34	nuclear factor kappa B subunit 1	Homo sapiens	99-108
11976000-6	2002	RDX is sequentially degraded to nitroso-, dinitroso-, trinitroso- and hydroxylaminodinitroso-RDX before the triazine ring is presumably cleaved, forming methanol and formaldehyde as major end products.	Methanol	153-161	radixin	Homo sapiens	0-3
11997013-3	2002	The 20 structures of moricin in methanol have been determined from two-dimensional 1H-nuclear magnetic resonance spectroscopic data.	Methanol	32-40	moricin-2	Bombyx mori	21-28
11976000-6	2002	RDX is sequentially degraded to nitroso-, dinitroso-, trinitroso- and hydroxylaminodinitroso-RDX before the triazine ring is presumably cleaved, forming methanol and formaldehyde as major end products.	Methanol	153-161	radixin	Homo sapiens	93-96
11934573-1	2002	A simple and efficient synthesis of nicotinamide riboside (NAR) 1 and derivatives 4 and 5 via trimethylsilyl trifluoromethanesulfonate (TMSOTf)-mediated N-glycosilation followed by spontaneous deacetylation by treating with methanol is reported.	Methanol	224-232	cytosolic iron-sulfur assembly component 3	Homo sapiens	36-65
11931710-3	2002	PI3 -K was assayed by incubating recombinant PI3-K p110beta with phosphatidylinositol-4,5-bisphosphate and [gamma-32P]ATP; the [32 P]-radiolabeled lipids were extracted with chloroform and methanol, assessed by thin layer chromatography and visualized by autoradiography.	Methanol	189-197	peptidase inhibitor 3	Homo sapiens	0-3
11925208-6	2002	Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement.	Methanol	52-60	complement C2	Homo sapiens	75-78
11925208-6	2002	Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement.	Methanol	52-60	complement C6	Homo sapiens	82-85
11999134-1	2002	This study was carried out to investigate the antifibrotic effects of methanol extracts from the traditional Chinese medicinal herb, the root of Scutellaria baicalensis Georgi, on liver fibrosis induced by bile duct ligation and scission (BDL) or carbon tetrachloride (CCl4) in rats.	Methanol	70-78	C-C motif chemokine ligand 4	Rattus norvegicus	269-273
11975521-1	2002	As part of a search for novel inhibitors of cathepsin K, the MeOH extract of a Micronesian sponge of the order Haplosclerida was shown to be active.	Methanol	61-65	cathepsin K	Homo sapiens	44-55
11931710-3	2002	PI3 -K was assayed by incubating recombinant PI3-K p110beta with phosphatidylinositol-4,5-bisphosphate and [gamma-32P]ATP; the [32 P]-radiolabeled lipids were extracted with chloroform and methanol, assessed by thin layer chromatography and visualized by autoradiography.	Methanol	189-197	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	51-59
11999134-7	2002	A methanol extract of S. baicalensis root inhibits fibrosis and lipid peroxidation in rat liver induced by BDL or CCl4.	Methanol	2-10	C-C motif chemokine ligand 4	Rattus norvegicus	114-118
11911460-2	2002	The methanol extract from Fiatoua villosa among 100 traditional edible plants that were tested, showed the most potent inhibitory effect (51%) on acetylcholinesterase in vitro.	Methanol	4-12	acetylcholinesterase	Rattus norvegicus	146-166
11990994-2	2002	Due to the mixed reversed-phase and cation-exchange mode of the Oasis MCX sorbent the cationic cytokinin bases, ribosides and glucosides as well as the anionic auxin, abscisic acid and cytokinin ribotides are retained and can be sequentially eluted by solvents containing different concentrations of methanol and ammonium hydroxide.	Methanol	300-308	cAMP responsive element binding protein 3 like 1	Homo sapiens	64-69
11932487-1	2002	In a previous report we have shown that the endothelin-B receptor-selective linear endothelin peptide, ET-1[Cys (Acm)1,15, Ala3, Leu7, Aib11], folds into an alpha-helical conformation in a methanol-d3/water co-solvent [Hewage et al.	Methanol	189-197	endothelin receptor type B	Homo sapiens	44-65
11932487-1	2002	In a previous report we have shown that the endothelin-B receptor-selective linear endothelin peptide, ET-1[Cys (Acm)1,15, Ala3, Leu7, Aib11], folds into an alpha-helical conformation in a methanol-d3/water co-solvent [Hewage et al.	Methanol	189-197	endothelin 1	Homo sapiens	103-111
11932487-1	2002	In a previous report we have shown that the endothelin-B receptor-selective linear endothelin peptide, ET-1[Cys (Acm)1,15, Ala3, Leu7, Aib11], folds into an alpha-helical conformation in a methanol-d3/water co-solvent [Hewage et al.	Methanol	189-197	beta-1,3-glucuronyltransferase 1	Homo sapiens	129-133
11750883-12	2001	The DAGAT activity was restored from delipidated oil bodies and from microsomes after the preparations had been resuspended in methanol/acetic acid/water (1:1:1, v/v).	Methanol	127-135	Diacylglycerol O-acyltransferase 1-2	Zea mays	4-9
11872005-0	2002	The effect of methanol washing of plasticized polyvinyl chloride on biomaterial-contact-mediated CD11b (mac-1) expression in a rat recirculation model.	Methanol	14-22	integrin subunit alpha M	Rattus norvegicus	97-102
11872005-1	2002	Our objective was to assess whether using a methanol wash to reduce the level of plasticizer present on the surface of medical-grade polyvinyl chloride (PVC) has a moderating effect on the expression of CD11b (mac-1) on neutrophils in rats undergoing recirculation.	Methanol	44-52	integrin subunit alpha M	Rattus norvegicus	203-208
11872005-7	2002	There was statistically significant (p < 0.001) lower Cd11b expression on neutrophils in the blood of rats perfused through the cell containing methanol-washed PVC after 30 min and at 60 min.	Methanol	147-155	integrin subunit alpha M	Rattus norvegicus	57-62
11872005-8	2002	CD11b expression was significantly (p < 0.001) lower in the control group than in both test groups at both the 30 and 60 min time points and at the 60 min time point on comparison with the group where blood was perfused through methanol-washed PVC.	Methanol	231-239	integrin subunit alpha M	Rattus norvegicus	0-5
11872005-9	2002	These results demonstrate that the biomaterial-contact-mediated upregulation of CD11b may be significantly reduced by employing a methanol-washing technique on the plasticized PVC.	Methanol	130-138	integrin subunit alpha M	Rattus norvegicus	80-85
11767121-2	2001	The MeOH extract of the seeds of Rhynchosia volubilis (Leguminosae) showed antiproliferative activity against human gastric adenocarcinoma [MK-1, 50% growth inhibition (GI50): 25 microg/ml], human uterus carcinoma (HeLa, GI50: 30 microg/ml), and murine melanoma (B16F10, GI50: 8 microg/ml) cells.	Methanol	4-8	icos ligand	Mus musculus	169-173
11767121-2	2001	The MeOH extract of the seeds of Rhynchosia volubilis (Leguminosae) showed antiproliferative activity against human gastric adenocarcinoma [MK-1, 50% growth inhibition (GI50): 25 microg/ml], human uterus carcinoma (HeLa, GI50: 30 microg/ml), and murine melanoma (B16F10, GI50: 8 microg/ml) cells.	Methanol	4-8	icos ligand	Mus musculus	221-225
11767121-2	2001	The MeOH extract of the seeds of Rhynchosia volubilis (Leguminosae) showed antiproliferative activity against human gastric adenocarcinoma [MK-1, 50% growth inhibition (GI50): 25 microg/ml], human uterus carcinoma (HeLa, GI50: 30 microg/ml), and murine melanoma (B16F10, GI50: 8 microg/ml) cells.	Methanol	4-8	icos ligand	Mus musculus	221-225
11846686-4	2002	Thus, N5(-) is predicted to have t(1/2) = 2.2 d, while the half-lifetime for HN5 is expected to be only about 10 min in methanol at 0 degrees C. Controlled ozonolysis of 2b-NBu4 followed by 1H and 15N NMR spectroscopy shows a preferential destruction of the N5 ring, which excludes it from possible methods for preparation of the parent pentazole.	Methanol	120-128	MT-RNR2 like 5 (pseudogene)	Homo sapiens	77-80
11846692-1	2002	A series of beta-(trimethylsilyl)ethoxymethyl ethers were hydrolyzed to their corresponding alcohols in high yields by using a catalytic amount of CBr4 (15%) in MeOH under refluxing reaction conditions.	Methanol	161-165	carbonyl reductase 4	Homo sapiens	147-151
11846692-3	2002	The selectivity also can be achieved in the CBr4/MeOH reaction mixture under ultrasonic reaction conditions.	Methanol	49-53	carbonyl reductase 4	Homo sapiens	44-48
11831906-12	2002	Ester hydrolysis with Ba(OH)(2)/MeOH gave the target prodrug 2a which is a substrate for beta-glucuronidase.	Methanol	32-36	glucuronidase beta	Homo sapiens	89-107
16228561-5	2002	The activity of Phedase was inhibited by the reaction product, methanol.	Methanol	63-71	pheophorbidase	Raphanus sativus	16-23
11811897-6	2001	The bioassay-directed analysis of flavonols 1-3 indicated that kaempferol (3) was the most active compound contained in the MeOH extract because it reduced in vitro both NO production and iNOS expression in LPS-primed J774.A1 cells, whereas rutin (1) and kaempferol 3-O-rutinoside (2) showed no significant activity.	Methanol	124-128	nitric oxide synthase 2, inducible	Mus musculus	188-192
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	144-152	BCL2 apoptosis regulator	Homo sapiens	73-78
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	144-152	BCL2 associated X, apoptosis regulator	Homo sapiens	83-86
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	191-199	BCL2 apoptosis regulator	Homo sapiens	73-78
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	191-199	BCL2 associated X, apoptosis regulator	Homo sapiens	83-86
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	191-199	BCL2 apoptosis regulator	Homo sapiens	73-78
11759062-1	2001	The authors recently showed variable subcellular immunoreactivity of the Bcl-2 and Bax proteins after fixation of cell monolayers with acetone, methanol, or paraformaldehyde (PF) followed by methanol (PF/methanol).	Methanol	191-199	BCL2 associated X, apoptosis regulator	Homo sapiens	83-86
11717168-2	2001	beta-Glucuronidase activity was assayed using 4-methylumbelliferyl-glucuronide and methanol extracts of rat plasma containing luteolin monoglucuronide.	Methanol	83-91	glucuronidase, beta	Rattus norvegicus	0-18
11580285-2	2001	When dissolved in or cast from methanol as a dried film, A(24) is predominantly alpha-helical.	Methanol	31-39	immunoglobulin kappa variable 2-23 (pseudogene)	Homo sapiens	57-62
11910757-3	2001	Recombinant matrix metalloproteinase-2 protein was expressed in Pichia pastoris in great deal after induction by methanol.	Methanol	113-121	matrix metallopeptidase 2	Homo sapiens	12-38
11910758-1	2001	In order to enhance the expression level of human trefoil factor 3 (hTFF3) in Pichia pastoris, we optimized the transformant growth conditions in shake flasks including carbon sources in growth medium, inoculation ratio, methanol concentration, pH rotation speed and inducing time.	Methanol	221-229	trefoil factor 3	Homo sapiens	50-66
11910758-1	2001	In order to enhance the expression level of human trefoil factor 3 (hTFF3) in Pichia pastoris, we optimized the transformant growth conditions in shake flasks including carbon sources in growth medium, inoculation ratio, methanol concentration, pH rotation speed and inducing time.	Methanol	221-229	trefoil factor 3	Homo sapiens	68-73
11910758-4	2001	The expression level of dimeric human trefoil factor 3 induction with 1% methanol for 48 hours at pH 6.0, agitation speed 240 r/min could reach 20 mg/L with OD600 15.	Methanol	73-81	trefoil factor 3	Homo sapiens	38-54
11876438-6	2001	It was found that a 0.05 mol l(-1) LiCl solution, containing 18% of methanol, at pH 4.0 adjusted with orthophosphoric acid, is suitable for the separation of 4-APh and paracetamol from each other and from other pharmaceutical excipients present in tablets.	Methanol	68-76	acylaminoacyl-peptide hydrolase	Homo sapiens	160-163
11574725-1	2001	The structure of the title methanol complex (P1;, Z = 2) has been determined and compared with that of the title ethanol complex (C2/c, Z = 8) using published data.	Methanol	27-35	crystallin gamma F, pseudogene	Homo sapiens	45-55
11574725-1	2001	The structure of the title methanol complex (P1;, Z = 2) has been determined and compared with that of the title ethanol complex (C2/c, Z = 8) using published data.	Methanol	27-35	complement C2	Homo sapiens	130-141
15348357-7	2001	Metalloproteinase (MMP-2) activity was detected in all the samples analyzed but a higher expression of MMP-9 was detected in those implants treated with chloroform/methanol and ethanol.	Methanol	164-172	matrix metallopeptidase 2	Rattus norvegicus	19-24
15348357-7	2001	Metalloproteinase (MMP-2) activity was detected in all the samples analyzed but a higher expression of MMP-9 was detected in those implants treated with chloroform/methanol and ethanol.	Methanol	164-172	matrix metallopeptidase 9	Rattus norvegicus	103-108
11556805-0	2001	Methanol toxicity and formate oxidation in NEUT2 mice.	Methanol	0-8	aldehyde dehydrogenase 1 family, member L1	Mus musculus	43-48
11556805-6	2001	The absence of FDH should impair the oxidation of formate via the folate-dependent pathway and as a consequence render homozygous NEUT2 mice more susceptible to methanol toxicity.	Methanol	161-169	aldehyde dehydrogenase 1 family, member L1	Mus musculus	15-18
11556805-6	2001	The absence of FDH should impair the oxidation of formate via the folate-dependent pathway and as a consequence render homozygous NEUT2 mice more susceptible to methanol toxicity.	Methanol	161-169	aldehyde dehydrogenase 1 family, member L1	Mus musculus	130-135
11556805-7	2001	Normal (CB6-F1) and NEUT2 heterozygous and homozygous mice had essentially identical LD(50) values for methanol, 6.08, 6.00, and 6.03 g/kg, respectively.	Methanol	103-111	aldehyde dehydrogenase 1 family, member L1	Mus musculus	20-25
12240416-0	2001	Highly diastereoselective dihydride formation by activation of methanol with IrCl((S)-binap)(PPh3).	Methanol	63-71	caveolin 1	Homo sapiens	93-97
11600024-4	2001	The calculated polychromatic quantum efficiencies (Phi(solvent)) of acifluorfen in different solvents are as follows (units are degraded molecules photon(-1)): Phi(water) = 10(-4), Phi(acetonitrile) = 10(-4), Phi(methanol) = 10(-4), and Phi(hexane) = 10(-2).	Methanol	213-221	glucose-6-phosphate isomerase	Homo sapiens	51-54
11559066-2	2001	The reduction of Cr(VI) in methanol in the presence of amino acids glycine, alanine, and 2-amino-2-methylpropanoic acid (alpha-aminoisobutyric acid, Aib) yielded several Cr(V) EPR signals.	Methanol	27-35	ANIB1	Homo sapiens	149-152
11516162-2	2001	With this system, the mouse DAF CCP1-4-active-domain-containing module linked to a 6x His tag at its C terminus was secreted into the culture supernatant at 15 mg/L after 24 h of induction with methanol.	Methanol	194-202	CD55 molecule, decay accelerating factor for complement	Mus musculus	28-31
11520031-1	2001	Pulmonary surfactant protein SP-C has been isolated from porcine lungs and treated with dansyl isothiocyanate in chloroform:methanol 2:1 (v/v) solutions,under conditions optimized to introduce a single dansyl group covalently attached to the N-terminalamine group of the protein without loss of its native thioesther-linked palmitic chains.	Methanol	124-132	surfactant protein C	Homo sapiens	29-33
11516162-2	2001	With this system, the mouse DAF CCP1-4-active-domain-containing module linked to a 6x His tag at its C terminus was secreted into the culture supernatant at 15 mg/L after 24 h of induction with methanol.	Methanol	194-202	granzyme F	Mus musculus	32-38
12545444-2	2001	Results demonstrated that 100% ethanol and 100% methanol solvents could induce the production of isomers of MAGE-2, while 100% DMSO, 50% ethanol and 50% methanol could not.	Methanol	48-56	MAGE family member A2B	Homo sapiens	108-114
12545444-2	2001	Results demonstrated that 100% ethanol and 100% methanol solvents could induce the production of isomers of MAGE-2, while 100% DMSO, 50% ethanol and 50% methanol could not.	Methanol	153-161	MAGE family member A2B	Homo sapiens	108-114
11511198-3	2001	The ligands dpk-OH(-) and dpk-CH3O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	108-116	potassium two pore domain channel subfamily K member 1	Homo sapiens	12-15
12580108-3	2001	Chromatography column was a Rp-18; the mobile phase was methanol-water (90:10); the flow rate was 1.0 mL.min-1 and the detecting wavelength was 220 nm.	Methanol	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
12776430-2	2001	METHOD: HPLC was carried out on a Shim-pack CLC-ODS column using MeOH-H2O-HOAc-TEA (83:17:0.04:0.02).	Methanol	65-69	Charcot-Leyden crystal galectin	Homo sapiens	44-47
11511198-3	2001	The ligands dpk-OH(-) and dpk-CH3O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	108-116	potassium two pore domain channel subfamily K member 1	Homo sapiens	26-29
11511198-3	2001	The ligands dpk-OH(-) and dpk-CH3O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	108-116	potassium two pore domain channel subfamily K member 1	Homo sapiens	26-29
11414039-5	2001	The use of less temperature/methanol fraction combinations requires a suitable estimation of alpha and delta Hdes, as their choice may change the obtained Koc values by up to a factor of 10.	Methanol	28-36	insulin like growth factor 2 mRNA binding protein 3	Homo sapiens	155-158
11486889-3	2001	Because FAME/CTME analyses are encountered very frequently in the food industry, an automated, robot-based alternative is proposed which uses the sodium methylate procedure.	Methanol	146-162	benign adult familial myoclonic epilepsy 1	Homo sapiens	8-12
11429388-2	2001	For short-chain alcohols from methanol to 1-hexanol, potency for inhibition of GluR1 and GluR3 receptor-mediated current increased in proportion to the chain length or hydrophobicity of the alcohol.	Methanol	30-38	glutamate receptor, ionotropic, AMPA 1 L homeolog	Xenopus laevis	79-84
11429388-2	2001	For short-chain alcohols from methanol to 1-hexanol, potency for inhibition of GluR1 and GluR3 receptor-mediated current increased in proportion to the chain length or hydrophobicity of the alcohol.	Methanol	30-38	glutamate receptor, ionotropic, AMPA 3 L homeolog	Xenopus laevis	89-94
11489599-13	2001	Methylation of Hoxc-8 appeared to be increased in embryos treated with 4 mg MeOH/mL CM, but not in embryos treated with 8 mg MeOH/mL.	Methanol	76-80	homeobox C8	Mus musculus	15-21
12947653-1	2001	Based on a highly sensitive new generation confocal microprobe Raman system, the adsorption behavior of thiocyanate (SCN-) on a gold electrode in methanol solution was investigated by SERS for the first time.	Methanol	146-154	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	184-188
11428671-2	2001	A methanol extract of Verbena littoralis H. B. K. collected in Paraguay only slightly potentiated the proportion of PC12D cells with neurites but markedly increased the length of neurites in the presence of NGF (2 ng mL(-1)).	Methanol	2-10	nerve growth factor	Rattus norvegicus	207-210
11378282-4	2001	The MeOH extract of rhizomes of C. rotundus showed the inhibition of NO production in a dose-dependent manner by RAW 264.7 cells stimulated with interferon-gamma plus lipopolysaccharide.	Methanol	4-8	interferon gamma	Mus musculus	145-161
11327890-0	2001	Modeling the active site chemistry of liver alcohol dehydrogenase: mononuclear zinc methanol and N,N-dimethylformamide complexes of a nitrogen/sulfur ligand possessing an internal hydrogen bond donor.	Methanol	84-92	aldo-keto reductase family 1 member A1	Homo sapiens	44-65
11340656-2	2001	Experimental studies indicate that while the helical fold of SP-C is thermodynamically stable in phospholipid micelles, it is metastable in a mixed organic solvent of CHCl3/CH3OH/0.1 M HCl at 32:64:5 (v/v/v), in which it undergoes an irreversible transformation to an insoluble aggregate that contains beta-sheet.	Methanol	173-178	surfactant protein C	Homo sapiens	61-65
11370738-0	2001	Alcohol and aldehyde dehydrogenase activity measured with fluorogenic substrates in the liver of rats poisoned with methanol.	Methanol	116-124	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	12-34
11476158-0	2001	Alcohol and aldehyde dehydrogenase activity in the stomach and small intestine of rats poisoned with methanol.	Methanol	101-109	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	12-34
11476158-1	2001	The activities of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) were measured with fluorogenic naphthaldehydes in the stomach and small intestine homogenates of rats dosed with 6 g methanol/kg bw after 6, 12, 24 h and 2, 5, 7 days.	Methanol	197-205	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	74-78
11795517-5	2001	As a result, both water and methanol extracts were found to cause not only significant increases in rat liver cytosolic SOD, catalase, and GSEH-px activities, but also a significant decrease in MDA production in TBA reactant assay in rats.	Methanol	28-36	catalase	Rattus norvegicus	125-133
11370738-2	2001	The activities of alcohol (ADH) and aldehyde dehydrogenase (ALDH) in the liver of rats dosed with 1.5 and 3 g of methanol/kg b.w.	Methanol	113-121	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	60-64
11370738-4	2001	The methanol intoxication led to a dose dependent induction of ADH and ALDH activities.	Methanol	4-12	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	71-75
11370738-7	2001	It is evident that sublethal methanol intoxication induces the hepatic activities of ADH and ALDH measured with fluorogenic substrates, and this induction depends on the dose of this alcohol.	Methanol	29-37	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	93-97
11323233-10	2001	This carbonyl complex was used for the direct labelling of surfactant protein B (SP-B) under non-reductive conditions by direct incubation with SP-B at elevated temperature followed by extraction into CHCl(3)/MeOH.	Methanol	209-213	surfactant protein B	Homo sapiens	59-79
11308323-2	2001	Among the growth/induction media used, buffered minimal glycerol (BMG)/buffered minimal methanol (BMM) media were best for the production of glycosylated bovine beta-casein, indicating pH-dependent glycosylation.	Methanol	88-96	casein beta	Bos taurus	161-172
11323233-10	2001	This carbonyl complex was used for the direct labelling of surfactant protein B (SP-B) under non-reductive conditions by direct incubation with SP-B at elevated temperature followed by extraction into CHCl(3)/MeOH.	Methanol	209-213	surfactant protein B	Homo sapiens	81-85
11300894-8	2001	On the contrary, reduction with NaBH(4) in MeOH at -15 degrees C produced the syn isomer 23 with >10:1 diastereoselectivity.	Methanol	43-47	synemin	Homo sapiens	78-81
11261977-3	2001	The "dimer-of-dimers", 3, was synthesized by a 2:1 reaction of [Ru2(O2CCH3)2(mhp)2(MeOH)](BF4) with [As(Ph)4]2[DM-Dicyd].	Methanol	83-88	doublecortin domain containing 2	Homo sapiens	64-67
11277419-7	2001	Whereas nuclear and mitotic immunoreactivity for Bcl-2 was clearly present after formaldehyde and methanol fixation, it was completely absent in cells fixed in acetone, methanol, or formaldehyde alone.	Methanol	98-106	BCL2 apoptosis regulator	Homo sapiens	49-54
11381548-3	2001	In order to simplify and improve this process a membrane system was conceived able to induce acid 2-ketogluconic diffusion from fermentation broth directly into methanol where it esterificates.	Methanol	161-169	PTOV1 extended AT-hook containing adaptor protein	Homo sapiens	93-99
11300845-4	2001	Electron transfer from Rh(2)(O(2)CCH(3))(4)(PPh(3))(2) to 4,4"-dimethyl viologen (MV(2+)) and chloro-p-benzoquinone (Cl-BQ) takes place with quenching rate constants (k(q)) of 8.0 x 10(6) and 1.2 x 10(6) M(-1) s(-1) in methanol, respectively.	Methanol	219-227	enolase 1	Homo sapiens	44-47
11300845-5	2001	A k(q) value of 2 x 10(8) M(-1) s(-1) was measured for the quenching of the excited state of Rh(2)(O(2)CCH(3))(4)(PPh(3))(2) by O(2) in methanol.	Methanol	136-144	enolase 1	Homo sapiens	114-117
11277419-7	2001	Whereas nuclear and mitotic immunoreactivity for Bcl-2 was clearly present after formaldehyde and methanol fixation, it was completely absent in cells fixed in acetone, methanol, or formaldehyde alone.	Methanol	169-177	BCL2 apoptosis regulator	Homo sapiens	49-54
11298235-2	2001	METHODS AND RESULTS: In fed-batch culture, the production of rPIN-a decreased after 24 h of methanol induction.	Methanol	92-100	ATPase copper transporting beta	Rattus norvegicus	61-67
11231926-7	2001	Ethanol, methanol, isopropanol, tert-butanol, and red wine all potentiated oxysterol-induced cell death up to 5-fold, paralleled by further induction of caspase-3.	Methanol	9-17	caspase 3	Homo sapiens	153-162
11281607-0	2001	The methanol-induced conformational transitions of beta-lactoglobulin, cytochrome c, and ubiquitin at low pH: a study by electrospray ionization mass spectrometry.	Methanol	4-12	cytochrome c, somatic	Homo sapiens	71-83
11281607-1	2001	The methanol-induced conformational transitions under acidic conditions for beta-lactoglobulin, cytochrome c, and ubiquitin, representing three different classes of proteins with beta-sheets, alpha-helices, and both alpha-helices and beta-sheets, respectively, are studied under equilibrium conditions by electrospray ionization mass spectrometry (ESI-MS).	Methanol	4-12	cytochrome c, somatic	Homo sapiens	96-108
11181486-10	2001	Starving rats gavaged with methanol extract of feces (500 mg/kg/day for 3 days) showed a 3.3-fold increase in CYP2E1 mRNA level in the liver.	Methanol	27-35	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	110-116
11159803-7	2001	Methanol was found to inhibit CYP2C9 and CYP2E1 activities, but to a lesser extent than DMSO.	Methanol	0-8	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	30-36
11172179-2	2001	The inhibition of alcohol dehydrogenase is fundamental to the treatment of methanol poisoning.	Methanol	75-83	aldo-keto reductase family 1 member A1	Homo sapiens	18-39
11172179-3	2001	We performed a multicenter study to evaluate fomepizole, an inhibitor of alcohol dehydrogenase, in the treatment of patients with methanol poisoning.	Methanol	130-138	aldo-keto reductase family 1 member A1	Homo sapiens	73-94
11877065-1	2001	OBJECTIVE: To express recombinant human platelet factor 4 (PF4) in methanol yeast.	Methanol	67-75	platelet factor 4	Homo sapiens	40-57
11877065-1	2001	OBJECTIVE: To express recombinant human platelet factor 4 (PF4) in methanol yeast.	Methanol	67-75	platelet factor 4	Homo sapiens	59-62
11159803-7	2001	Methanol was found to inhibit CYP2C9 and CYP2E1 activities, but to a lesser extent than DMSO.	Methanol	0-8	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	41-47
11205516-4	2001	To optimise the operating conditions methyl 4-formylbenzoate, premixed with sodium methoxide, was reacted with 2-nitrobenzyl-triphenylphosphonium bromide in dry degassed MeOH using flow conditions for both reagents of 0.40 microL min-1 for 20 min.	Methanol	170-174	CD59 molecule (CD59 blood group)	Homo sapiens	230-235
11237628-6	2001	This is in the order of the octanol partition coefficients multiplied by spin exchange rate constants that were determined for the different paramagnetic salts in methanol.	Methanol	163-171	spindlin 1	Homo sapiens	73-77
11195371-3	2001	The fast process of [Fe(btpa)](PF6)2 with a rate constant, kHL, of 2.5 x 10(7) s-1 at 295 K and an activation energy, Ea, of 1294(26) cm-1 in methanol can be assigned to the 5T2-->1A1 relaxation as well.	Methanol	142-150	sperm associated antigen 17	Homo sapiens	31-34
11338776-3	2001	It was found that OCT, while completely insoluble in water, forms solid gel structures when in equimolar mixtures of water and methanol.	Methanol	127-135	plexin A2	Homo sapiens	18-21
12035057-4	2001	After the induction by 2% methanol for 48 hours, the expression of dimeric hTFF3 came up to 45% of total proteins in medium, as identified by SDS-PAGE and Western blot assay.	Methanol	26-34	trefoil factor 3	Homo sapiens	75-80
11196080-2	2001	The German MAK (threshold limit value) of methanol is 200 ppm.	Methanol	42-50	male germ cell associated kinase	Homo sapiens	11-14
11746901-2	2001	In this study, conformational changes in BE induced by methanol are explored with electrospray ionization-mass spectrometry (ESI-MS).	Methanol	55-63	proopiomelanocortin	Homo sapiens	41-43
11746901-5	2001	Both these techniques demonstrate that BE exists in a random coil open structure in aqueous media, but it acquires a more compact conformation with increased concentration of methanol.	Methanol	175-183	proopiomelanocortin	Homo sapiens	39-41
11125832-1	2000	Trityl ethers are selectively deprotected to the corresponding alcohols in high yields by CBr4 in refluxing methanol under neutral reaction conditions.	Methanol	108-116	carbonyl reductase 4	Homo sapiens	90-94
11162875-6	2000	The results proved that the use of methanol and N-acetylcysteine increased the activities of Cu,Zn-superoxide dismutase, glutathione peroxidase and glutathione reductase by about 15,15 and 41%, respectively, in comparison to the group of rats receiving methanol alone.	Methanol	35-43	glutathione-disulfide reductase	Rattus norvegicus	148-169
11162875-6	2000	The results proved that the use of methanol and N-acetylcysteine increased the activities of Cu,Zn-superoxide dismutase, glutathione peroxidase and glutathione reductase by about 15,15 and 41%, respectively, in comparison to the group of rats receiving methanol alone.	Methanol	253-261	glutathione-disulfide reductase	Rattus norvegicus	148-169
11137122-3	2000	Soluble bovine TNF-RI was secreted into the medium following induction of the AOX1 gene promoter with methanol, and purified to greater than 95% purity by ion-exchange chromatography.	Methanol	102-110	TNF receptor superfamily member 1A	Bos taurus	15-21
11199480-8	2000	Using immunohistochemistry on methanol/acetic acid-fixed, paraffin-embedded pancreas, the CCKA receptor could successfully be localized in islet cells.	Methanol	30-38	cholecystokinin A receptor	Rattus norvegicus	90-103
11113999-4	2000	We found that endotoxin-free methanol extracts from PM leaves, at doses of 50, 100, 250, and 500 microg/mL, were associated with 4.4 +/- 1, 6 +/- 1, 12 +/- 0.4, and 18 +/- 0.4-fold increases of nitric oxide (NO) production, and increased TNF-alpha production (621 +/- 31, 721 +/- 36, 727 +/- 36, and 1056 +/- 52 U/mL, respectively) by rat peritoneal macrophages, in the absence of IFN-gamma or LPS.	Methanol	29-37	interferon gamma	Rattus norvegicus	381-390
11237093-4	2000	The half-life for decomposition (tau(1/2)) of the unsymmetrical initiators at 37 degrees C in methanol covered a range of 121 hours for SA-1, 77 hours for SA-2, and approximately 25 hours for the series C-16, C-12, and C-8.	Methanol	94-102	stromal antigen 1	Homo sapiens	136-140
11237093-4	2000	The half-life for decomposition (tau(1/2)) of the unsymmetrical initiators at 37 degrees C in methanol covered a range of 121 hours for SA-1, 77 hours for SA-2, and approximately 25 hours for the series C-16, C-12, and C-8.	Methanol	94-102	stromal antigen 2	Homo sapiens	155-159
11084289-6	2000	In model experiments using Fe(3+)-catalyzed nucleophilic addition of methanol or tert-butanol to the respective spin trap the respective alkoxyl radical adducts were formed in aqueous solution as transient species in the presence of high concentrations of the alcohol.	Methanol	69-77	spindlin 1	Homo sapiens	112-116
11087427-0	2000	Methanol-induced conformations of myoglobin at pH 4.0.	Methanol	0-8	myoglobin	Homo sapiens	34-43
11085361-2	2000	The MeOH extract showed the strongest inhibitory effect on D-GalN/TNF-alpha-induced cell death (IC50, 56.4 microg/ml).	Methanol	4-8	galanin and GMAP prepropeptide	Mus musculus	61-65
11008133-0	2000	Promitogenic effects of ethanol, methanol, and ethanolamine in insulin-treated fibroblasts.	Methanol	33-41	insulin	Cricetulus griseus	63-70
10992240-4	2000	In addition, the rates of asymmetric sulfoxidation of thioanisole in isopropyl alcohol and in methanol catalyzed by horseradish peroxidase (HRP) were determined to be tens to hundreds of times faster than in water under otherwise identical conditions.	Methanol	94-102	peroxidase	Glycine max	128-138
11085361-2	2000	The MeOH extract showed the strongest inhibitory effect on D-GalN/TNF-alpha-induced cell death (IC50, 56.4 microg/ml).	Methanol	4-8	tumor necrosis factor	Mus musculus	66-75
11085361-3	2000	Moreover, the MeOH extract also significantly lowered the serum glutamic pyruvic transaminase (sGPT) level on D-GalN/lipopolysaccharide (LPS)-induced liver injury in mice.	Methanol	14-18	galanin and GMAP prepropeptide	Mus musculus	112-116
11095183-1	2000	In continuation of our studies on the determination of the structural features of functionalized peptides in solution by combining time-resolved fluorescence data and molecular mechanics results, the conformational properties of a series of linear, homo-Aib peptides in methanol (a structure-supporting solvent) were investigated.	Methanol	270-278	ANIB1	Homo sapiens	254-257
11073261-2	2000	The charge state distributions of cytochrome c and myoglobin, formed from 47%/50%/3% water/solvent/acetic acid solutions, shift to lower charge (higher m/z) when the 50% solvent fraction is changed from water to methanol, to acetonitrile, to isopropanol.	Methanol	212-220	cytochrome c, somatic	Homo sapiens	34-46
11073261-2	2000	The charge state distributions of cytochrome c and myoglobin, formed from 47%/50%/3% water/solvent/acetic acid solutions, shift to lower charge (higher m/z) when the 50% solvent fraction is changed from water to methanol, to acetonitrile, to isopropanol.	Methanol	212-220	myoglobin	Homo sapiens	51-60
11095184-6	2000	NMR analysis establishes that the four-stranded sheet in Beta-4 is appreciably populated in 50% (v/v) aqueous methanol.	Methanol	110-118	tubulin beta 3 class III	Homo sapiens	57-63
10978507-1	2000	We isolated the promoter regions of five methanol-inducible genes (P(AOD1), alcohol oxidase; P(DAS1), dihydroxyacetone synthase; P(FDH1), formate dehydrogenase; P(PMP20), Pmp20; and P(PMP47), Pmp47) from the Candida boidinii genome, and evaluated their strength and studied their regulation using the acid phosphatase gene of Saccharomyces cerevisiae (ScPHO5) as the reporter.	Methanol	41-49	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	95-99
11045470-1	2000	Acidic segment of an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor, R-106578 was synthesized by enantioselective hydrogenation of the Z-olefine (9-(Z)) using (R)-2,2"-bis(diphenylphosphino)-1,1"-binaphthyl (BINAP)-Ru(OAc)2 as a catalyst in methanol at 100 degrees C, 5 kgf/cm2 of H2 pressure.	Methanol	249-257	sterol O-acyltransferase 1	Homo sapiens	21-58
11045470-1	2000	Acidic segment of an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor, R-106578 was synthesized by enantioselective hydrogenation of the Z-olefine (9-(Z)) using (R)-2,2"-bis(diphenylphosphino)-1,1"-binaphthyl (BINAP)-Ru(OAc)2 as a catalyst in methanol at 100 degrees C, 5 kgf/cm2 of H2 pressure.	Methanol	249-257	sterol O-acyltransferase 1	Homo sapiens	60-64
20617115-1	2000	The reaction of [ReOCl(3)(PPh(3))(2)] with salicylaldehyde-2-mercaptoanil (1) in methanol yields [ReO(OCH(3))(PPh(3))(eta(3)-OC(6)H(4)CH=NC(6)H(4)S)] (3).	Methanol	81-89	endothelin receptor type A	Homo sapiens	118-121
10978507-1	2000	We isolated the promoter regions of five methanol-inducible genes (P(AOD1), alcohol oxidase; P(DAS1), dihydroxyacetone synthase; P(FDH1), formate dehydrogenase; P(PMP20), Pmp20; and P(PMP47), Pmp47) from the Candida boidinii genome, and evaluated their strength and studied their regulation using the acid phosphatase gene of Saccharomyces cerevisiae (ScPHO5) as the reporter.	Methanol	41-49	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	129-135
10978507-2	2000	Of the five promoters, P(DAS1) was the strongest methanol-inducible promoter whose strength was approximately 1.5 times higher than that of the commonly used P(AOD1) in methanol-induced cells.	Methanol	49-57	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	23-29
10978507-2	2000	Of the five promoters, P(DAS1) was the strongest methanol-inducible promoter whose strength was approximately 1.5 times higher than that of the commonly used P(AOD1) in methanol-induced cells.	Methanol	169-177	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	23-29
10978507-5	2000	The induction kinetics of P(PMP47) and P(DAS1) revealed that methanol induces the expression of peroxisome membrane protein Pmp47, earlier than the expression of matrix enzyme dihydroxyacetone synthase (Das1p), and that this information is contained in the promoter region of the respective gene.	Methanol	61-69	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	39-45
10919373-1	2000	A crude methanol extract of Picrorhizae Rhizoma, the dried underground parts of Picrorhiza scrophulariiflora PENNELL, has been shown to potentiate the nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells.	Methanol	8-16	nerve growth factor	Rattus norvegicus	172-175
10930346-0	2000	Approximate Selection Rules for  K  = 1-0 and 1-1 Tunneling-Rotation Transitions in the Methanol Dimer.	Methanol	88-96	keratin 10	Homo sapiens	33-47
10956023-2	2000	We describe a new isomerization, that of L-2-hydroxyglutarate to L-threo-3-methylmalate, involving the migration of the carbinol carbon.	Methanol	120-128	immunoglobulin kappa variable 3-15	Homo sapiens	41-44
10946831-8	2000	The MeOH extract showed marked inhibition of NO production by activated RAW 264.7 cells in a dose-dependent manner via suppression of inducible NO synthase mRNA expression.	Methanol	4-8	nitric oxide synthase 2, inducible	Mus musculus	134-155
10959955-7	2000	The increased wetting of the C18 interphase in the order water < methanol < acetonitrile < tetrahydrofuran agreed with data for the miscibility of these solvents with n-hexadecane.	Methanol	68-76	Bardet-Biedl syndrome 9	Homo sapiens	29-32
10825179-1	2000	The Bacillus subtilis McpB is a class III chemotaxis receptor, from which methanol is released in response to all stimuli.	Methanol	74-82	hlyB-like ABC transporter-like protein	Escherichia coli	22-26
10825179-4	2000	McpB((Q371D,E630D,E637D)) in a Delta(mcpA mcpB tlpA tlpB)101::cat mcpC4::erm background failed to release methanol in response to either the addition or removal of the McpB-mediated attractant asparagine.	Methanol	106-114	hlyB-like ABC transporter-like protein	Escherichia coli	0-4
10825179-5	2000	In the same background, McpB((E630D,E637D)) produced methanol only upon asparagine addition, whereas McpB((Q371D,E630D)) produced methanol only upon asparagine removal.	Methanol	53-61	hlyB-like ABC transporter-like protein	Escherichia coli	24-28
10825179-5	2000	In the same background, McpB((E630D,E637D)) produced methanol only upon asparagine addition, whereas McpB((Q371D,E630D)) produced methanol only upon asparagine removal.	Methanol	130-138	hlyB-like ABC transporter-like protein	Escherichia coli	101-105
10825179-6	2000	Thus methanol release from McpB was selective.	Methanol	5-13	hlyB-like ABC transporter-like protein	Escherichia coli	27-31
10888749-5	2000	The TL5 cell culture smears showed that methanol fixation, followed by heat-induced antigen retrieval, is the most suitable technique for p27(Kip1) staining on cytological samples.	Methanol	40-48	zinc ribbon domain containing 2	Homo sapiens	138-141
10888749-5	2000	The TL5 cell culture smears showed that methanol fixation, followed by heat-induced antigen retrieval, is the most suitable technique for p27(Kip1) staining on cytological samples.	Methanol	40-48	cyclin dependent kinase inhibitor 1B	Homo sapiens	142-146
11196900-0	2000	Supramolecular complex of cytochrome c with lariat ether: solubilization, redox behavior and catalytic activity of cytochrome c in methanol.	Methanol	131-139	cytochrome c, somatic	Homo sapiens	26-38
11196900-0	2000	Supramolecular complex of cytochrome c with lariat ether: solubilization, redox behavior and catalytic activity of cytochrome c in methanol.	Methanol	131-139	cytochrome c, somatic	Homo sapiens	115-127
11196900-1	2000	A variety of lariat ethers were employed to solubilize water-soluble cytochrome c in methanol, in which alcohol, ether, ester, amine, and amide functionalities were attached as cation-ligating side arms to 18-crown-6, 15-crown-5, and 12-crown-4 rings.	Methanol	85-93	cytochrome c, somatic	Homo sapiens	69-81
11196900-3	2000	The resulting cytochrome c-lariat ether complexes were electrochemically and spectroscopically characterized and confirmed to have redox-active heme structures of 6-coordinate low-spin population in methanol.	Methanol	199-207	cytochrome c, somatic	Homo sapiens	14-26
11196900-4	2000	Some of them catalyzed the oxidation of pinacyanol chloride with hydrogen peroxide in methanol and exhibited higher activities than unmodified cytochrome c and its poly(ethylene glycolated) derivative.	Methanol	86-94	cytochrome c, somatic	Homo sapiens	143-155
11051816-3	2000	After 4 days of 1% methanol induction, the expressed Flt-1(1-3) accumulated up to 30% of total proteins in supernatant.	Methanol	19-27	fms related receptor tyrosine kinase 1	Homo sapiens	53-58
10843635-0	2000	Photolysis of ((3-(Trimethylsilyl)propoxy)phenyl)phenyliodonium salts in the presence of 1-naphthol and 1-methoxynaphthalene Direct photolysis of ((3-trimethylsilylpropoxy)phenyl)phenyliodonium salts with different counteranions (Cl(-), SbF(6)(-), and B(C(6)F(5))(4)(-)) in methanol leads to products by both heterolytic and homolytic processes.	Methanol	274-282	zinc finger protein 143	Homo sapiens	237-240
10791967-10	2000	Eg7 and AKAP95 immunofluorescently colocalize to the central region of methanol-fixed metaphase chromosomes.	Methanol	71-79	A-kinase anchoring protein 8	Homo sapiens	8-14
10857362-0	2000	Photosensitized reduction of methyl viologen using eosin-Y in presence of a sacrificial electron donor in water-alcohol mixture Photoreduction of methyl viologen (MV2+) by eosin-Y (EY2-) in the presence of triethanolamine (TEOA) has been investigated in water-methanol mixture by means of steady-state photolysis and laser-flash photolysis in the visible/near-infrared regions.	Methanol	260-268	ENY2 transcription and export complex 2 subunit	Homo sapiens	181-184
10885484-2	2000	1 crystallizes with one molecule of methanol in the monoclinic space group P2(1)/c with a = 1332.3(7), b = 669.9(2), c = 1809.0(8) pm, beta = 100.96(4) degrees, and Z = 4.	Methanol	36-44	cyclin dependent kinase inhibitor 1A	Homo sapiens	75-80
10794719-3	2000	Here we study the membrane-induced conformational change of Apo H by CD spectroscopy with two different model systems: anionic-phospholipid-containing liposomes [such as 1, 2-dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) and cardiolipin], and the water/methanol mixtures at moderately low pH, which mimic the micro-physicochemical environment near the membrane surface.	Methanol	255-263	apolipoprotein H	Homo sapiens	60-65
10794719-6	2000	The similar conformation change in Apo H can be induced by treatment with an appropriate mixture of water/methanol.	Methanol	106-114	apolipoprotein H	Homo sapiens	35-40
10845788-2	2000	Raman spectroscopy is used to characterize the behavior of the C18 bonded ligands equilibrated at temperatures from 45 to 2 degrees C in neat, single-component, mobile phase solvents including: water, acetonitrile, methanol, and chloroform.	Methanol	215-223	Bardet-Biedl syndrome 9	Homo sapiens	63-66
10843593-1	2000	The combined CH(2)Cl(2) and MeOH crude extract of a new species of the marine sponge Dysidea, collected in Northern Australia was found to inhibit the binding of [I125] interleukin-8 [IL-8] to the human recombinant IL-8 receptor type A at 500 microg/mL.	Methanol	28-32	C-X-C motif chemokine ligand 8	Homo sapiens	169-182
10843593-1	2000	The combined CH(2)Cl(2) and MeOH crude extract of a new species of the marine sponge Dysidea, collected in Northern Australia was found to inhibit the binding of [I125] interleukin-8 [IL-8] to the human recombinant IL-8 receptor type A at 500 microg/mL.	Methanol	28-32	C-X-C motif chemokine ligand 8	Homo sapiens	184-188
10843593-1	2000	The combined CH(2)Cl(2) and MeOH crude extract of a new species of the marine sponge Dysidea, collected in Northern Australia was found to inhibit the binding of [I125] interleukin-8 [IL-8] to the human recombinant IL-8 receptor type A at 500 microg/mL.	Methanol	28-32	C-X-C motif chemokine ligand 8	Homo sapiens	215-219
10784427-1	2000	The MeOH extract of leaves of Combretum quadrangulare showed significant hepatoprotective effect on D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced experimental liver injury in mice and on D-GalN/tumor necrosis factor-alpha (TNF-alpha)-induced cell death in primary cultured mouse hepatocytes.	Methanol	4-8	galanin and GMAP prepropeptide	Mus musculus	119-123
10784427-1	2000	The MeOH extract of leaves of Combretum quadrangulare showed significant hepatoprotective effect on D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced experimental liver injury in mice and on D-GalN/tumor necrosis factor-alpha (TNF-alpha)-induced cell death in primary cultured mouse hepatocytes.	Methanol	4-8	galanin and GMAP prepropeptide	Mus musculus	201-205
10784427-1	2000	The MeOH extract of leaves of Combretum quadrangulare showed significant hepatoprotective effect on D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced experimental liver injury in mice and on D-GalN/tumor necrosis factor-alpha (TNF-alpha)-induced cell death in primary cultured mouse hepatocytes.	Methanol	4-8	tumor necrosis factor	Mus musculus	235-244
10701257-4	2000	Boron trifluoride (BF3) and HC1/methanol were adopted as the cyclization/cleavage and conversion reagents to suppress the amino acid residue racemization.	Methanol	32-40	CYCS pseudogene 39	Homo sapiens	28-31
10845776-5	2000	[3H]Palmitoylation of synaptobrevin 2 was resistant to chloroform/methanol extraction, but sensitive to reducing agents indicating a covalent fatty acid bond to cysteine residues.	Methanol	66-74	vesicle-associated membrane protein 2	Rattus norvegicus	22-37
12541595-3	2000	When supercritical carbon dioxide or low concentration(less than 0.5%) of methanol is employed as the mobile phase, retention time increases with the polarity of the solvent on NH2 column, while it keeps almost constant on C18 column.	Methanol	74-82	Bardet-Biedl syndrome 9	Homo sapiens	223-226
12541595-6	2000	So it"s quite more evident on NH2 column than on C18 column that the delaying effect of the solvent, with methanol, acetone and chloroform in decreasing sequence, encourages the elution of the analytes during continuous injections.	Methanol	106-114	Bardet-Biedl syndrome 9	Homo sapiens	49-52
10757164-5	2000	The mechanism responsible for this difference in behavior of lyso-GPC subtypes was consistent with a higher proton affinity of carboxyl carbonyl oxygen atoms and vinyl ether oxygen atoms found in acyl and plasmenyl lyso-GPC lipids, respectively, as compared to the carbinol oxygen atom common to all lyso-GPC species.	Methanol	265-273	glycophorin C (Gerbich blood group)	Homo sapiens	66-69
10757164-5	2000	The mechanism responsible for this difference in behavior of lyso-GPC subtypes was consistent with a higher proton affinity of carboxyl carbonyl oxygen atoms and vinyl ether oxygen atoms found in acyl and plasmenyl lyso-GPC lipids, respectively, as compared to the carbinol oxygen atom common to all lyso-GPC species.	Methanol	265-273	glycophorin C (Gerbich blood group)	Homo sapiens	220-223
10757164-5	2000	The mechanism responsible for this difference in behavior of lyso-GPC subtypes was consistent with a higher proton affinity of carboxyl carbonyl oxygen atoms and vinyl ether oxygen atoms found in acyl and plasmenyl lyso-GPC lipids, respectively, as compared to the carbinol oxygen atom common to all lyso-GPC species.	Methanol	265-273	glycophorin C (Gerbich blood group)	Homo sapiens	220-223
10782245-7	2000	This result reflected the inhibition of methanol oxidation by alcohol-dehydrogenase, when the plasma ethanol concentration was above 1 g.L-1.	Methanol	40-48	aldo-keto reductase family 1 member A1	Homo sapiens	62-83
10702494-0	2000	Sequential use of paraformaldehyde and methanol as optimal conditions for the direct quantification of ZEBRA and rta antigens by flow cytometry.	Methanol	39-47	MAS related GPR family member F	Homo sapiens	103-116
11129983-3	2000	We show here that the percentage of P-gp epitopes available for labeling with UIC2 monoclonal antibody is increased significantly after methanol permeabilization/fixation of cells.	Methanol	136-144	ATP binding cassette subfamily B member 1	Homo sapiens	36-40
11272530-6	2000	The reaction of 1 with methanol in tetrahydrofuran (THF) gave compound [Mg4(mu3-OMe)2(mu,eta2-ddbfo)2(mu,eta1-ddbfo)2(eta1-ddbfo)2(CH3OH)5] x CH3OH x THF (2).	Methanol	23-31	DNA polymerase iota	Homo sapiens	89-93
11272530-6	2000	The reaction of 1 with methanol in tetrahydrofuran (THF) gave compound [Mg4(mu3-OMe)2(mu,eta2-ddbfo)2(mu,eta1-ddbfo)2(eta1-ddbfo)2(CH3OH)5] x CH3OH x THF (2).	Methanol	23-31	secreted phosphoprotein 1	Homo sapiens	105-109
11272530-6	2000	The reaction of 1 with methanol in tetrahydrofuran (THF) gave compound [Mg4(mu3-OMe)2(mu,eta2-ddbfo)2(mu,eta1-ddbfo)2(eta1-ddbfo)2(CH3OH)5] x CH3OH x THF (2).	Methanol	23-31	secreted phosphoprotein 1	Homo sapiens	118-122
10601866-1	2000	The secondary structure and membrane-associated conformation of a synthetic peptide corresponding to the putative membrane-binding C-terminal 38 residues of the bovine milk component PP3 was determined using 1H NMR in methanol, CD in methanol and SDS micelles, and 15N solid-state NMR in planar phospholipid bilayers.	Methanol	218-226	glycosylation dependent cell adhesion molecule 1	Bos taurus	183-186
10601866-1	2000	The secondary structure and membrane-associated conformation of a synthetic peptide corresponding to the putative membrane-binding C-terminal 38 residues of the bovine milk component PP3 was determined using 1H NMR in methanol, CD in methanol and SDS micelles, and 15N solid-state NMR in planar phospholipid bilayers.	Methanol	234-242	glycosylation dependent cell adhesion molecule 1	Bos taurus	183-186
10601866-2	2000	The solution NMR and CD spectra reveal that the PP3 peptide in methanol and SDS predominantly adopts an alpha-helical conformation extending over its entire length with a potential bend around residue 19.	Methanol	63-71	glycosylation dependent cell adhesion molecule 1	Bos taurus	48-51
16232852-5	2000	Methanol as an external carbon source was added during the anoxic phase to reduce nitrate nitrogen (NO3-) when denitrification was completed.	Methanol	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	100-103
16232878-2	2000	The expression of midkine was efficiently induced by methanol in a high cell density fermentation.	Methanol	53-61	midkine	Homo sapiens	18-25
10666016-1	2000	The activity of the Santolina chamaecyparissus methanol extract was tested against the phospholipase A2 (PLA2)-induced mouse paw edema and in vitro inhibition of PLA2 activity.	Methanol	47-55	phospholipase A2, group V	Mus musculus	105-109
10661886-2	2000	Methanol extract of Orostachys japonicus A. Berger (Crassulaceae), a traditional oriental medical herb, was shown to have a protective effect on H2O2-induced apoptosis in GT1-1 mouse hypothalamic neuronal cell line which was detected by flow cytometry after propidium iodide staining.	Methanol	0-8	retinoic acid induced 1	Mus musculus	171-176
11192467-6	2000	Although the roles of alcohol dehydrogenase inhibition with ethanol or fomepizole and hemodialysis are clear in the case of toxic ingestions of methanol and ethylene glycol, they remain poorly defined for butoxyethanol poisoning.	Methanol	144-152	aldo-keto reductase family 1 member A1	Homo sapiens	22-43
10666016-1	2000	The activity of the Santolina chamaecyparissus methanol extract was tested against the phospholipase A2 (PLA2)-induced mouse paw edema and in vitro inhibition of PLA2 activity.	Methanol	47-55	phospholipase A2, group V	Mus musculus	162-166
12058192-5	2000	After 4 days of methanol induction, the amount of the expressed Flt-1s reached 60% of total proteins in supernatant by SDS-PAGE.	Methanol	16-24	fms related receptor tyrosine kinase 1	Homo sapiens	64-69
10229864-4	1999	However, more than 80% of methanol-fixed CD34+ cells do bind MIP-1alpha, suggesting that these cells may possess a pool of internal receptors, although we were unable to induce cell surface expression by cytokine stimulation.	Methanol	26-34	CD34 molecule	Homo sapiens	41-45
10601636-4	1999	It was shown earlier that a portion of another NER protein, PCNA, which is completely extractable from non-S-phase mammalian nuclei, becomes insoluble after ultraviolet (UV) light irradiation and cannot be extracted by methanol or buffer containing Triton X-100.	Methanol	219-227	proliferating cell nuclear antigen	Homo sapiens	60-64
10591966-4	1999	In methanol-grown cells of a P. pastoris VPS15 deletion strain, the levels of peroxisomal marker enzymes remained high after addition of excess glucose or ethanol.	Methanol	3-11	ubiquitin-binding serine/threonine protein kinase VPS15	Saccharomyces cerevisiae S288C	41-46
10531654-5	1999	One His+ clone which has eight copies of the expression cassette per genome was cultured in minimal medium deficient for histidine, and further cultured in buffered medium supplemented with methanol which activates the AOX1 promoter.	Methanol	190-198	aldehyde oxidase 1	Mus musculus	219-223
10465754-8	1999	Significant band-broadening and asymmetric and split peaks were also observed for bombesin, beta-endorphin, and glucagon at different temperatures and methanol concentrations.	Methanol	151-159	gastrin releasing peptide	Homo sapiens	82-90
10465754-8	1999	Significant band-broadening and asymmetric and split peaks were also observed for bombesin, beta-endorphin, and glucagon at different temperatures and methanol concentrations.	Methanol	151-159	proopiomelanocortin	Homo sapiens	92-106
10496315-5	1999	By immunofluorescence, EG1 and EG2 at 20 microg/mL stained 95-100% of nonstimulated eosinophils, regardless of fixative; EG1 and EG2 at 0.1 microg/mL stained 61-90% of acetone- and paraformaldehyde-fixed and only 5-21% of methanol-fixed nonstimulated eosinophils.	Methanol	222-230	mediator complex subunit 28	Homo sapiens	23-26
10457436-5	1999	The loss of resolution with larger injection volume appears to be a result of the injection solvent, methanol, modifying the composition of the mobile phase both in the CN guard column and in the initial portion of the C18 column.	Methanol	101-109	Bardet-Biedl syndrome 9	Homo sapiens	219-222
10478824-0	1999	Activity of cathepsin G, elastase, and their inhibitors in plasma during methanol intoxication.	Methanol	73-81	cathepsin G	Rattus norvegicus	12-33
10478824-4	1999	The activity of cathepsin G and elastase was increased from 12 h to 5 d, proportionally to methanol dose.	Methanol	91-99	cathepsin G	Rattus norvegicus	16-40
10425145-1	1999	Activity-guided fractionation of a methanol extract of the leaves of Ilex kudincha led to the isolation of seven acyl CoA cholesteryl acyl transferase (ACAT) inhibitory triterpenes.	Methanol	35-43	carboxylesterase 1	Homo sapiens	113-150
10425145-1	1999	Activity-guided fractionation of a methanol extract of the leaves of Ilex kudincha led to the isolation of seven acyl CoA cholesteryl acyl transferase (ACAT) inhibitory triterpenes.	Methanol	35-43	carboxylesterase 1	Homo sapiens	152-156
10524772-0	1999	Methanol-induced unfolding and refolding of cytochrome b5 and its P40V mutant monitored by UV-visible, CD, and fluorescence spectra.	Methanol	0-8	cytochrome b5 type A	Homo sapiens	44-57
10524772-2	1999	Unfolding and refolding of Cyt b5 induced by methanol was investigated by means of the UV-visible spectrum, circular dichroism, and the fluorescence spectrum.	Methanol	45-53	cytochrome b5 type A	Homo sapiens	27-33
10524772-3	1999	Methanol denaturation of Cyt b5 is a cooperative process, that is, the heme group dissociates from the heme pocket accompanied by unfolding of the polypeptide chain both in the secondary and tertiary structures.	Methanol	0-8	cytochrome b5 type A	Homo sapiens	25-31
10387098-14	1999	At a given temperature above -2 degrees C, both the shortening and ATPase rates were reduced by the methanol.	Methanol	100-108	dynein axonemal heavy chain 8	Homo sapiens	67-73
10624880-5	1999	The generation of NO as well as the expression of inducible nitric oxide synthase (iNOS) protein from IFN-gamma primed RAW 264.7 cells is markedly decreased by the methanol extract in a dose dependent manner.	Methanol	164-172	nitric oxide synthase 2, inducible	Mus musculus	50-81
10624880-5	1999	The generation of NO as well as the expression of inducible nitric oxide synthase (iNOS) protein from IFN-gamma primed RAW 264.7 cells is markedly decreased by the methanol extract in a dose dependent manner.	Methanol	164-172	nitric oxide synthase 2, inducible	Mus musculus	83-87
10624880-5	1999	The generation of NO as well as the expression of inducible nitric oxide synthase (iNOS) protein from IFN-gamma primed RAW 264.7 cells is markedly decreased by the methanol extract in a dose dependent manner.	Methanol	164-172	interferon gamma	Mus musculus	102-111
10574697-8	1999	Optimization of methanol-induction conditions resulted in a high-methanol shake-flask expression protocol yielding significantly increased CEA N-A3 levels.	Methanol	16-24	CEA cell adhesion molecule 3	Homo sapiens	139-142
10574697-8	1999	Optimization of methanol-induction conditions resulted in a high-methanol shake-flask expression protocol yielding significantly increased CEA N-A3 levels.	Methanol	65-73	CEA cell adhesion molecule 3	Homo sapiens	139-142
10617314-5	1999	Methanol administration, increasing concentration of the lipid peroxidation products, decreased the liver glutathione-peroxidase and glutathione reductase (GSSG-R) activities, GSH concentration and total antioxidant status (TAS).	Methanol	0-8	glutathione-disulfide reductase	Rattus norvegicus	133-154
10477824-10	1999	However, SP-B can be recovered from the walls of polypropylene and Teflon tubes by washing with chloroform:methanol.	Methanol	107-115	surfactant protein B	Canis lupus familiaris	9-13
10456774-0	1999	Beta-lactam degradation catalysed by Cd2+ ion in methanol.	Methanol	49-57	CD2 molecule	Homo sapiens	37-40
11671080-8	1999	The width of an empty cavity of Co(C6[16]Cyc) shrinks by 0.3 A in methanol solution, as compared to vacuum simulations.	Methanol	66-74	cytochrome c, somatic	Homo sapiens	41-44
10704036-3	1999	The molar absorptivity of Cu(II)-S,S"-bis(2-aminophenyl)oxalate complex in methanol is 5365 M(-1) cm(-1) at 504 nm.	Methanol	75-83	secretoglobin family 1D member 4	Homo sapiens	26-34
10229864-4	1999	However, more than 80% of methanol-fixed CD34+ cells do bind MIP-1alpha, suggesting that these cells may possess a pool of internal receptors, although we were unable to induce cell surface expression by cytokine stimulation.	Methanol	26-34	C-C motif chemokine receptor 1	Homo sapiens	61-71
10227189-8	1999	A C18 column was used with a mobile phase of methanol/water (40 + 60, V/V for for the herbicide residues were 1.0 microgram/l and 3 micrograms/kg in water and soil, respectively.	Methanol	45-53	Bardet-Biedl syndrome 9	Homo sapiens	2-5
10367351-2	1999	The capacity of the straight chain primary alcohols (methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol) to release the enzymes glutamate-pyruvate transaminase (GPT), lactate dehydrogenase (LDH) and glutamate dehydrogenase (GLDH) into the perfusate was strongly correlated with their carbon chain length.	Methanol	53-61	glutamic--pyruvic transaminase	Rattus norvegicus	133-164
10367351-2	1999	The capacity of the straight chain primary alcohols (methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol) to release the enzymes glutamate-pyruvate transaminase (GPT), lactate dehydrogenase (LDH) and glutamate dehydrogenase (GLDH) into the perfusate was strongly correlated with their carbon chain length.	Methanol	53-61	glutamic--pyruvic transaminase	Rattus norvegicus	166-169
10426229-7	1999	However, a methanol extract of Corethane samples that were incubated for 28 days in cholesterol esterase did show the presence of MDA.	Methanol	11-19	carboxyl ester lipase	Homo sapiens	84-104
10209984-0	1999	Methanol/acetone treatment helps the amplification of FMR1 CGG repeat fragment in dried blood spots from Guthrie cards.	Methanol	0-8	fragile X messenger ribonucleoprotein 1	Homo sapiens	54-58
18505532-2	1999	Among the 150 plants, six plant extracts (final concentration 1 mg/ml in methanol) exhibited more than 65% of inhibition of elastase activity.	Methanol	73-81	elastase, neutrophil expressed	Homo sapiens	124-132
10698532-2	1999	Investigation using deuterium-labeled oxycodone and analysis by LC/MS showed that gem diol and hemiketal adducts of oxycodone formed as a result of the equilibrium addition of water and methanol to the C-6 ketone on oxycodone.	Methanol	186-194	complement C6	Homo sapiens	202-205
10220294-3	1999	On the other hand, cis-form chalcones, which were isomerized from the original trans-forms by irradiation of daylight in methanol solution, promoted the activity of human aldose reductase.	Methanol	121-129	aldo-keto reductase family 1 member B	Homo sapiens	171-187
10927344-7	1999	L-Leucyl-L-valine-methanol (1/1) crystallizes in the space group P2(1) with Z = 2.	Methanol	18-26	H3 histone pseudogene 16	Homo sapiens	65-70
9929510-3	1999	Methanol did not substantially inhibit (</=10%) any of the activities at 0.3%, but did inhibit CYP1A1, CYP2B6, CYP2C9, and CYP2D6 by 12 to 26% at 1%.	Methanol	0-8	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	98-104
9929510-3	1999	Methanol did not substantially inhibit (</=10%) any of the activities at 0.3%, but did inhibit CYP1A1, CYP2B6, CYP2C9, and CYP2D6 by 12 to 26% at 1%.	Methanol	0-8	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	106-112
9929510-3	1999	Methanol did not substantially inhibit (</=10%) any of the activities at 0.3%, but did inhibit CYP1A1, CYP2B6, CYP2C9, and CYP2D6 by 12 to 26% at 1%.	Methanol	0-8	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	114-120
9929510-3	1999	Methanol did not substantially inhibit (</=10%) any of the activities at 0.3%, but did inhibit CYP1A1, CYP2B6, CYP2C9, and CYP2D6 by 12 to 26% at 1%.	Methanol	0-8	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	126-132
10202953-7	1999	The results also confirmed the increase of extractability power of TFA when it was added to methanol: the recovery for the analytes (cocaine and its metabolites and opiates) added to methanol-TFA alone was of the order of 90% except for benzoylecgonine (75%), and the recovery for the analytes added to methanol-TFA extract of drug-free hair was about 90% for all analytes except for benzoylecgonine and 6-MAM (around 70%).	Methanol	183-191	sarcoglycan gamma	Homo sapiens	406-409
10202953-7	1999	The results also confirmed the increase of extractability power of TFA when it was added to methanol: the recovery for the analytes (cocaine and its metabolites and opiates) added to methanol-TFA alone was of the order of 90% except for benzoylecgonine (75%), and the recovery for the analytes added to methanol-TFA extract of drug-free hair was about 90% for all analytes except for benzoylecgonine and 6-MAM (around 70%).	Methanol	183-191	sarcoglycan gamma	Homo sapiens	406-409
10082309-5	1999	A formaldehyde-methanol fixation procedure was optimized for retention of p105 within mitotic cells by analytic titration of formaldehyde.	Methanol	15-23	nuclear factor kappa B subunit 1	Homo sapiens	74-78
10231710-1	1999	The solution structure of a biologically active modified linear endothelin-1 analogue, ET1-21[Cys(Acm)1,15, Aib3,11, Leu7], has been determined for the first time by two-dimensional nuclear magnetic resonance spectroscopy in a methanol-d3/water solvent mixture.	Methanol	227-235	endothelin 1	Homo sapiens	64-76
10231710-1	1999	The solution structure of a biologically active modified linear endothelin-1 analogue, ET1-21[Cys(Acm)1,15, Aib3,11, Leu7], has been determined for the first time by two-dimensional nuclear magnetic resonance spectroscopy in a methanol-d3/water solvent mixture.	Methanol	227-235	endothelin 1	Homo sapiens	87-90
10036768-3	1999	The hSOD1 was purified from the cultured yeast by ammonium sulfate-methanol extraction and DEAE-cellulose column chromatography.	Methanol	67-75	superoxide dismutase 1	Homo sapiens	4-9
9950187-2	1999	Plasticized polyvinyl chloride before and after treatment with methanol to reduce the plasticizer surface level was assessed in terms of fibrinogen and albumin adsorption with unplasticized polyvinyl chloride acting as a control.	Methanol	63-71	fibrinogen beta chain	Homo sapiens	137-147
10407340-5	1999	After the purification step, the Oasis column effluent was directed to the analytical column and the mass spectrometer and the analytes were eluted with methanol/aqueous 1 mM formic acid (70:30) at a flow rate of 1.0 mL/min.	Methanol	153-161	cAMP responsive element binding protein 3 like 1	Homo sapiens	33-38
9874700-6	1999	CsA gave many new peaks in the 1H NMR spectrum when the solvent was changed from chloroform to methanol/water, suggesting conformational diversity of CsA in polar solvents.	Methanol	95-103	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	0-3
9874700-6	1999	CsA gave many new peaks in the 1H NMR spectrum when the solvent was changed from chloroform to methanol/water, suggesting conformational diversity of CsA in polar solvents.	Methanol	95-103	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	150-153
10697422-1	1999	The activity of lysosomal proteolytic enzymes (cathepsin A, B, C, D and E) in cytosol and in the whole homogenate of the liver and in the blood plasma from rats intoxicated with 1.5, 3.0 and 6.0 g methanol/kg b.w.	Methanol	197-205	cathepsin A	Rattus norvegicus	47-73
12078146-2	1999	METHOD: C18 column was used with methanol-0.06 mol/L potassium phosphate monobasic-tetrahydrofuran (10:150:1.5) as mobile phase.	Methanol	33-41	Bardet-Biedl syndrome 9	Homo sapiens	8-11
12110935-8	1999	SDS-PAGE analysis revealed that the human OPG/OCIF isoform was highly expressed and accumulated up to over 30% of soluble protein of yeast after the induction by methanol for 3 to 5 days.	Methanol	162-170	TNF receptor superfamily member 11b	Homo sapiens	42-45
12110935-8	1999	SDS-PAGE analysis revealed that the human OPG/OCIF isoform was highly expressed and accumulated up to over 30% of soluble protein of yeast after the induction by methanol for 3 to 5 days.	Methanol	162-170	TNF receptor superfamily member 11b	Homo sapiens	46-50
10199577-8	1999	Both TCE and methanol significantly induced CYP2E1 in rat liver.	Methanol	13-21	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	44-50
9865947-2	1998	The alpha-helical form of SP-C observed in freshly prepared solutions in a mixed solvent of CHCl3/CH3OH/0.1 M HCl 32:64:5 (v/v/v) at 10 degrees C undergoes within a few days an irreversible transformation to an insoluble aggregate that contains beta-sheet secondary structure.	Methanol	98-103	surfactant protein C	Homo sapiens	26-30
10335271-2	1998	The (E)-stilbene isomer (2a) of the (Z)-combretastatin A-4 prodrug (1b) was efficiently prepared from (E)-combretastatin A-4 by a reaction sequence employing phosphorylation (dibenzyl chlorophosphite), cleavage (trimethyliodosilane) of the benzyl ester and reaction of the resulting phosphoric acid with sodium methoxide.	Methanol	304-320	immunoglobulin kappa variable 1D-27 (pseudogene)	Homo sapiens	55-58
9740329-2	1998	The c-Abl monoclonal antibody (mAb), against the protein tyrosine kinase domain of v-Abl protein, reacted specifically with the acrosomal region of methanol-fixed capacitated and non-capacitated human sperm cell in the indirect immunofluorescence technique.	Methanol	148-156	ABL proto-oncogene 1, non-receptor tyrosine kinase	Homo sapiens	4-9
10065196-1	1998	The effects of the methanol extract of Spirostachys venenifera Pax (SVP) on the immune response in mice was investigated.	Methanol	19-27	paxillin	Mus musculus	63-66
9740329-2	1998	The c-Abl monoclonal antibody (mAb), against the protein tyrosine kinase domain of v-Abl protein, reacted specifically with the acrosomal region of methanol-fixed capacitated and non-capacitated human sperm cell in the indirect immunofluorescence technique.	Methanol	148-156	ABL proto-oncogene 1, non-receptor tyrosine kinase	Homo sapiens	83-88
9747846-3	1998	Enzymatically active, recombinant alpha-glucosidase was synthesized and secreted from the yeast upon induction with methanol.	Methanol	116-124	Agl1	Hordeum vulgare	34-51
9810262-1	1998	Total methanol extract of Saussurea lappa radix (Compositae) showed potent inhibitory effect on the production of tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine, in murine macrophage-like cell (RAW264.7 cells) in our previous screening studies on 120 Korean medicinal plants.	Methanol	6-14	tumor necrosis factor	Mus musculus	143-152
11670591-7	1998	Crystal data for the complex [Cu(2)L(1)(OMe)].MeOH: molecular formula C(30)H(39)ClCu(2)N(2)O(5), monoclinic, space group P2(1)/c with a = 13.222(1) A, b = 15.912(1) A, c = 14.149(1) A, beta = 91.64(1) degrees, and Z = 4.	Methanol	46-50	cyclin dependent kinase inhibitor 1A	Homo sapiens	121-126
9748331-9	1998	The ratio of methanolysis to hydrolysis for cADPR and NAD+ catalyzed by CD38 increases linearly with MeOH concentration.	Methanol	101-105	CD38 molecule	Homo sapiens	72-76
9653067-9	1998	Our results indicate that (1) methanol causes contractile responses of cerebral arterial smooth muscle (independent of amine, prostanoid, or opioid mediation; (2) in addition to a need for [Ca2+]o, an intracellular release of Ca2+ is required for methanol-induced contractions; and (3) Mg deficiency potentiates the contractile responses of methanol on these brain vessels.	Methanol	247-255	carbonic anhydrase 2	Canis lupus familiaris	226-229
9774234-3	1998	The peptide Boc-LAla-deltaPhe-deltaPhe-deltaPhe-deltaPhe+ ++-NHMe (C45H46N6O7, MW = 782.86) was crystallised from an acetonitrile/methanol mixture.	Methanol	130-138	BOC cell adhesion associated, oncogene regulated	Homo sapiens	12-15
9875472-2	1998	From the above screening, the methanol extract of Gentiana scabra showed a potent antagonistic activity against PAF.	Methanol	30-38	patchy fur	Mus musculus	112-115
9690341-1	1998	The inhibitory effects of methanol extracts of heartwood of 23 Papua New Guinean wood species on tyrosinase activity were examined.	Methanol	26-34	tyrosinase	Mus musculus	97-107
9653067-6	1998	Removal of extracellular Ca2+ ([Ca2+]o) partially attenuated methanol-induced contractions, while withdrawal of extracellular Mg2+ ([Mg2+]o) potentiated the contractions.	Methanol	61-69	carbonic anhydrase 2	Canis lupus familiaris	25-28
9653067-6	1998	Removal of extracellular Ca2+ ([Ca2+]o) partially attenuated methanol-induced contractions, while withdrawal of extracellular Mg2+ ([Mg2+]o) potentiated the contractions.	Methanol	61-69	carbonic anhydrase 2	Canis lupus familiaris	32-35
9806434-0	1998	In vitro studies of human alcohol dehydrogenase inhibition in the process of methanol and ethylene glycol oxidation.	Methanol	77-85	aldo-keto reductase family 1 member A1	Homo sapiens	26-47
9653067-9	1998	Our results indicate that (1) methanol causes contractile responses of cerebral arterial smooth muscle (independent of amine, prostanoid, or opioid mediation; (2) in addition to a need for [Ca2+]o, an intracellular release of Ca2+ is required for methanol-induced contractions; and (3) Mg deficiency potentiates the contractile responses of methanol on these brain vessels.	Methanol	247-255	carbonic anhydrase 2	Canis lupus familiaris	226-229
9653067-9	1998	Our results indicate that (1) methanol causes contractile responses of cerebral arterial smooth muscle (independent of amine, prostanoid, or opioid mediation; (2) in addition to a need for [Ca2+]o, an intracellular release of Ca2+ is required for methanol-induced contractions; and (3) Mg deficiency potentiates the contractile responses of methanol on these brain vessels.	Methanol	30-38	carbonic anhydrase 2	Canis lupus familiaris	190-193
9653067-9	1998	Our results indicate that (1) methanol causes contractile responses of cerebral arterial smooth muscle (independent of amine, prostanoid, or opioid mediation; (2) in addition to a need for [Ca2+]o, an intracellular release of Ca2+ is required for methanol-induced contractions; and (3) Mg deficiency potentiates the contractile responses of methanol on these brain vessels.	Methanol	30-38	carbonic anhydrase 2	Canis lupus familiaris	226-229
9653067-10	1998	The data presented in the study suggest that methanol-induced contractions occur via an sarcoplasmic reticulum-releasable store of [Ca2+]i; via mediation of either ryanodine-caffeine type receptors or a caffeine-releasable intracellular store of CA2+.	Methanol	45-53	carbonic anhydrase 2	Canis lupus familiaris	132-135
9653067-10	1998	The data presented in the study suggest that methanol-induced contractions occur via an sarcoplasmic reticulum-releasable store of [Ca2+]i; via mediation of either ryanodine-caffeine type receptors or a caffeine-releasable intracellular store of CA2+.	Methanol	45-53	carbonic anhydrase 2	Canis lupus familiaris	246-249
9585555-4	1998	The 8"-methyl carbinols are the only metabolites formed by CYP1A2, and substantial (70-80%) incorporation of oxygen from the medium into the carbinols is observed.	Methanol	14-23	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	59-65
9585555-9	1998	We conclude that oxidation of the 8-methyl group of furafylline and cyclohexylline, but not their N7-methyl analogues, by CYP1A2 promotes a major fraction of the inactivating xanthines to a two electron oxidized intermediate which either terminates enzyme activity by reaction with an active site amino acid or is decomposed by reaction with the medium to give carbinol.	Methanol	361-369	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	122-128
29711230-1	1998	With CoI corrins as supernucleophiles, methylation by methanol is achieved when the leaving group is activated by Zn2+ ions at elevated temperatures (see reaction below).	Methanol	54-62	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	5-8
11670337-4	1998	Crystals of L(Pr)WI(CO)(3).MeOH are orthorhombic, space group Pbca, with a = 11.779(2) A, b = 15.975(4) A, c = 29.476(3) A, and V = 5547(2) A(3) for Z = 8.	Methanol	27-31	PBCA	Homo sapiens	62-66
9547517-4	1998	Anti-Shc antibodies strongly reacted with the acrosomal region of methanol-fixed human sperm.	Methanol	66-74	SHC adaptor protein 1	Homo sapiens	5-8
9724926-3	1998	Here the functional expression of PEPT2 in the methylotropic yeast Pichia pastoris is described under the control of a methanol inducible promoter.	Methanol	119-127	solute carrier family 15 member 2 L homeolog	Xenopus laevis	34-39
9474757-1	1997	Enthalpy changes on the immersion of human serum albumin (HSA) into n-butanol, n-propanol, ethanol and methanol containing different amounts of water have been measured calorimetrically at 25 degrees C. Water sorption isotherms on HSA were also determined in water-n-butanol and water-ethanol mixtures.	Methanol	103-111	albumin	Homo sapiens	43-56
9494110-5	1998	We find that CD38-catalysed cleavage of the nicotinamide-ribose bond results in the formation of an E.ADP-ribosyl intermediary complex, which is common to all reaction pathways; this intermediate reacts (1) with acceptors such as water (hydrolysis), methanol (methanolysis) or pyridine (transglycosidation), and (2) intramolecularly, yielding cyclic ADP-ribose with a low efficiency.	Methanol	250-258	CD38 molecule	Homo sapiens	13-17
9551088-3	1998	The HSE-binding activity of HSF1 was induced by a number of chemical stresses including cadmium, aluminum, iron, mercury, arsenite, ethanol, methanol, and salicylate.	Methanol	141-149	heat shock factor protein	Xenopus laevis	28-32
9518582-2	1998	Pulmonary surfactant proteins SP-B and SP-C were isolated from the extracts using gel-exclusion chromatography on LH-60 with chloroform:methanol acidified with hydrochloric acid.	Methanol	136-144	surfactant protein C	Homo sapiens	39-43
9468474-0	1998	Pectin methylesterase regulates methanol and ethanol accumulation in ripening tomato (Lycopersicon esculentum) fruit.	Methanol	32-40	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	0-21
9468474-1	1998	We provide genetic evidence that the production of methanol in tomato fruit is regulated by pectin methylesterase (PME, EC 3.1.1.11), an enzyme that catalyzes demethoxylation of pectins.	Methanol	51-59	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	92-113
9468474-1	1998	We provide genetic evidence that the production of methanol in tomato fruit is regulated by pectin methylesterase (PME, EC 3.1.1.11), an enzyme that catalyzes demethoxylation of pectins.	Methanol	51-59	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	115-118
9468474-2	1998	The role of PME in methanol production in tomato fruit was examined by relating the tissue methanol content to the PME enzymatic activity in wild-type Rutgers and isogenic PME antisense fruits with lowered PME activity.	Methanol	19-27	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	12-15
9468474-4	1998	In the PME antisense pericarp, the level of methanol was greatly reduced in unripe fruit, and diminished methanol content persisted throughout the ripening process.	Methanol	44-52	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	7-10
9468474-4	1998	In the PME antisense pericarp, the level of methanol was greatly reduced in unripe fruit, and diminished methanol content persisted throughout the ripening process.	Methanol	105-113	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	7-10
9468474-5	1998	The close correlation between PME activity and levels of methanol in fruit tissues from wild-type and a PME antisense mutant indicates that PME is the primary biosynthetic pathway for methanol production in tomato fruit.	Methanol	57-65	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	104-107
9468474-5	1998	The close correlation between PME activity and levels of methanol in fruit tissues from wild-type and a PME antisense mutant indicates that PME is the primary biosynthetic pathway for methanol production in tomato fruit.	Methanol	57-65	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	104-107
9468474-5	1998	The close correlation between PME activity and levels of methanol in fruit tissues from wild-type and a PME antisense mutant indicates that PME is the primary biosynthetic pathway for methanol production in tomato fruit.	Methanol	184-192	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	30-33
9468474-5	1998	The close correlation between PME activity and levels of methanol in fruit tissues from wild-type and a PME antisense mutant indicates that PME is the primary biosynthetic pathway for methanol production in tomato fruit.	Methanol	184-192	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	104-107
9468474-5	1998	The close correlation between PME activity and levels of methanol in fruit tissues from wild-type and a PME antisense mutant indicates that PME is the primary biosynthetic pathway for methanol production in tomato fruit.	Methanol	184-192	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	104-107
9468474-7	1998	In vitro studies indicate that methanol is a competitive inhibitor of the tomato alcohol dehydrogenase (ADH, EC 1.1.1.1) activity suggesting that ADH-catalyzed production of ethanol may be arrested by methanol accumulation in the wild-type but not in the PME mutant where methanol levels remain low.	Methanol	31-39	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	255-258
9468474-7	1998	In vitro studies indicate that methanol is a competitive inhibitor of the tomato alcohol dehydrogenase (ADH, EC 1.1.1.1) activity suggesting that ADH-catalyzed production of ethanol may be arrested by methanol accumulation in the wild-type but not in the PME mutant where methanol levels remain low.	Methanol	201-209	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	255-258
9468474-7	1998	In vitro studies indicate that methanol is a competitive inhibitor of the tomato alcohol dehydrogenase (ADH, EC 1.1.1.1) activity suggesting that ADH-catalyzed production of ethanol may be arrested by methanol accumulation in the wild-type but not in the PME mutant where methanol levels remain low.	Methanol	201-209	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	255-258
9490763-8	1998	Of particular interest is the dramatic accumulation of FDH transcripts after spraying methanol on leaves, as this compound is known to increase the yields of C3 plants.	Methanol	86-94	formate dehydrogenase, mitochondrial	Solanum tuberosum	55-58
9730571-3	1998	Normal anion gap has been reported in some cases of concomitant methanol and ethanol ingestion, where the high serum levels of ethanol inhibited the metabolism of methanol by alcohol dehydrogenase.	Methanol	64-72	aldo-keto reductase family 1 member A1	Homo sapiens	175-196
9730571-3	1998	Normal anion gap has been reported in some cases of concomitant methanol and ethanol ingestion, where the high serum levels of ethanol inhibited the metabolism of methanol by alcohol dehydrogenase.	Methanol	163-171	aldo-keto reductase family 1 member A1	Homo sapiens	175-196
9398786-1	1997	Treatment of human methanol poisoning with the alcohol dehydrogenase inhibitor, 4-methylpyrazole (fomepizole), has not been previously described.	Methanol	19-27	aldo-keto reductase family 1 member A1	Homo sapiens	47-68
9567069-3	1998	MeOH-100% MeOH and MeOH-50% MeOH fractions (31.3 microgram/ml or higher) strongly inhibited an increase in endothelin-1 concentration in culture medium when they were added to a culture of glomerular cells derived from nephritic rats.	Methanol	0-4	endothelin 1	Rattus norvegicus	107-119
9567069-3	1998	MeOH-100% MeOH and MeOH-50% MeOH fractions (31.3 microgram/ml or higher) strongly inhibited an increase in endothelin-1 concentration in culture medium when they were added to a culture of glomerular cells derived from nephritic rats.	Methanol	10-14	endothelin 1	Rattus norvegicus	107-119
9567069-3	1998	MeOH-100% MeOH and MeOH-50% MeOH fractions (31.3 microgram/ml or higher) strongly inhibited an increase in endothelin-1 concentration in culture medium when they were added to a culture of glomerular cells derived from nephritic rats.	Methanol	10-14	endothelin 1	Rattus norvegicus	107-119
9567069-3	1998	MeOH-100% MeOH and MeOH-50% MeOH fractions (31.3 microgram/ml or higher) strongly inhibited an increase in endothelin-1 concentration in culture medium when they were added to a culture of glomerular cells derived from nephritic rats.	Methanol	10-14	endothelin 1	Rattus norvegicus	107-119
9567069-5	1998	Oral administration of the MeOH-100% MeOH fraction inhibited increase in endothelin-1 expression in the glomeruli of nephritic rats and in endothelin-1 production by a culture of glomerular cells derived from the nephritic rats.	Methanol	27-31	endothelin 1	Rattus norvegicus	73-85
9567069-5	1998	Oral administration of the MeOH-100% MeOH fraction inhibited increase in endothelin-1 expression in the glomeruli of nephritic rats and in endothelin-1 production by a culture of glomerular cells derived from the nephritic rats.	Methanol	27-31	endothelin 1	Rattus norvegicus	139-151
9567069-5	1998	Oral administration of the MeOH-100% MeOH fraction inhibited increase in endothelin-1 expression in the glomeruli of nephritic rats and in endothelin-1 production by a culture of glomerular cells derived from the nephritic rats.	Methanol	37-41	endothelin 1	Rattus norvegicus	73-85
9567069-5	1998	Oral administration of the MeOH-100% MeOH fraction inhibited increase in endothelin-1 expression in the glomeruli of nephritic rats and in endothelin-1 production by a culture of glomerular cells derived from the nephritic rats.	Methanol	37-41	endothelin 1	Rattus norvegicus	139-151
9567069-6	1998	Alisols A and B, the main constituents of the MeOH-100% MeOH fraction, inhibited in vitro endothelin-1 production by glomerular cells derived from the nephritic rats.	Methanol	46-50	endothelin 1	Rattus norvegicus	90-102
9567069-6	1998	Alisols A and B, the main constituents of the MeOH-100% MeOH fraction, inhibited in vitro endothelin-1 production by glomerular cells derived from the nephritic rats.	Methanol	56-60	endothelin 1	Rattus norvegicus	90-102
9355937-3	1997	In addition to the first four n-alcohols (methanol, ethanol, propanol and butanol) and phenol, whose capacity to induce HSP was analyzed earlier (Neuhaus-Steinmetz et al., 1994.	Methanol	42-50	selenoprotein K	Rattus norvegicus	120-123
9467970-0	1997	Solution structure determination of endothelin-1 in methanol/water by NMR and molecular modelling methods.	Methanol	52-60	endothelin 1	Homo sapiens	36-48
18636643-4	1997	The sensor was used to monitor methanol concentration continuously throughout a fed-batch shake-flask culture of a P. pastoris clone producing the N-lobe of human transferrin.	Methanol	31-39	transferrin	Homo sapiens	163-174
9648270-2	1997	It has been found that some cosolvents, such as Me2SO and MeOH, can be used up to 20% v/v without any influence on the performance of these enzymes, while others, such as tetrahydrofuran, rapidly inactivated GalT at concentrations as low as 5% v/v.	Methanol	58-62	galactose-1-phosphate uridylyltransferase	Bos taurus	208-212
9434603-5	1997	Methanol, tetrahydrofuran, and 1,4-dioxane extracts (50 micrograms/ml) inhibited leukotriene B4-induced migration of human PMNs by 90% and N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-induced degranulation by 25-35%.	Methanol	0-8	formyl peptide receptor 1	Homo sapiens	186-190
9467970-1	1997	To understand the structural requirements for the biological activity of endothelin peptides and to develop receptor selective endothelin analogues further, the solution structure of the bicyclic 21 amino acid residue vasoactive peptide, endothelin-1, has been determined in methanol-d3/water using high-resolution 1H-NMR spectroscopy.	Methanol	275-283	endothelin 1	Homo sapiens	238-250
9315869-0	1997	Acid-induced unfolding of cytochrome c at different methanol concentrations: electrospray ionization mass spectrometry specifically monitors changes in the tertiary structure.	Methanol	52-60	cytochrome c, somatic	Homo sapiens	26-38
9514124-3	1997	In a fed-batch fermenter, a cell density of approximately 300 mg/ml was achieved by controlled glycerol feeding for a total of 24 h. After 72 h of methanol induction, the secreted BLG reached levels of > 1 g/l.	Methanol	147-155	beta-lactoglobulin	Bos taurus	180-183
9390453-2	1997	One representative gcr1 cat mutant C-105 grows during batch cultivation in a glucose/methanol medium.	Methanol	85-93	transcription regulator GCR1	Saccharomyces cerevisiae S288C	19-23
9416465-4	1997	In liver homogenates, the activities of Cu,Zn-superoxide dismutase and catalase were significantly increased after 6 h following methanol ingestion in doses of 3.0 and 6.0 g/kg b.w.	Methanol	129-137	catalase	Rattus norvegicus	71-79
9390453-6	1997	These Mth+ gcr1 cat scd strains utilize methanol as a sole source of carbon and energy, although biomass yields are reduced relative to the wild-type strain.	Methanol	40-48	transcription regulator GCR1	Saccharomyces cerevisiae S288C	11-15
9307942-3	1997	The Schiff bases of the amino acids and myoglobin were obtained by reacting the aldehyde with an excess of isoleucine, valine, lysine, methyl ester lysine and myoglobin in aqueous methanol for 18 h at room temperature.	Methanol	180-188	myoglobin	Homo sapiens	40-49
9366096-1	1997	A methanol extract of hops of Humulus lupulus (L.) showed inhibitory activity against rat liver diacylglycerol acyltransferase (DGAT).	Methanol	2-10	diacylglycerol O-acyltransferase 1	Rattus norvegicus	96-126
9366096-1	1997	A methanol extract of hops of Humulus lupulus (L.) showed inhibitory activity against rat liver diacylglycerol acyltransferase (DGAT).	Methanol	2-10	diacylglycerol O-acyltransferase 1	Rattus norvegicus	128-132
9344799-0	1997	The Microwave Spectrum of the Methanol Dimer for K = 0 and 1 States The rotational spectrum of (CH3OH)2 has been observed in the 8 to 24 GHz region with a pulsed-beam Fabry-Perot cavity Fourier-transform microwave spectrometer.	Methanol	30-38	keratin 1	Homo sapiens	49-60
9417990-5	1997	Separation was achieved by preferential solubilization of non-glycosylated CHIP28 in CHCl3/MeOH/H2O mixtures.	Methanol	91-95	aquaporin 1 (Colton blood group)	Homo sapiens	75-81
9307942-3	1997	The Schiff bases of the amino acids and myoglobin were obtained by reacting the aldehyde with an excess of isoleucine, valine, lysine, methyl ester lysine and myoglobin in aqueous methanol for 18 h at room temperature.	Methanol	180-188	myoglobin	Homo sapiens	159-168
18259411-2	1997	The HO2 is formed by the 355-nm photolysis of Cl2 in the presence of CH3 OH and O2 and monitored by a phase-sensitive detection of the second-harmonic (2f ) signal in the 2?1 band with a 1.5- ?m diode laser directly modulated at 5 MHz.	Methanol	69-75	heme oxygenase 2	Homo sapiens	4-7
18259411-2	1997	The HO2 is formed by the 355-nm photolysis of Cl2 in the presence of CH3 OH and O2 and monitored by a phase-sensitive detection of the second-harmonic (2f ) signal in the 2?1 band with a 1.5- ?m diode laser directly modulated at 5 MHz.	Methanol	69-75	endogenous retrovirus group W member 5	Homo sapiens	46-49
9294881-0	1997	Critical periods of sensitivity to the developmental toxicity of inhaled methanol in the CD-1 mouse.	Methanol	73-81	CD1 antigen complex	Mus musculus	89-93
15806780-1	1997	In this paper, we have studied the fluorescence extinction effect of methyl alcohol by prostaglandinum E1 (PG E1) and found the linear relation between the fluorescence extinction intensity and prostaglandinum E1 concentration.	Methanol	69-83	small nucleolar RNA, H/ACA box 73A	Homo sapiens	103-112
11669984-1	1997	sigma-Bond metathesis reactions of water and methanol with palladium hydride and methyl complexes to yield hydrogen and methane, respectively, have been studied using ab-initio molecular orbital methods at the second-order Moller-Plesset (MP2) perturbation level.	Methanol	45-53	tryptase pseudogene 1	Homo sapiens	239-242
9226256-0	1997	Regulation of the formate dehydrogenase gene, FDH1, in the methylotrophic yeast Candida boidinii and growth characteristics of an FDH1-disrupted strain on methanol, methylamine, and choline.	Methanol	155-163	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	130-134
9226256-2	1997	In a batch culture experiment, although the fdh1 delta strain was still able to grow on methanol, its growth was greatly inhibited and a toxic level of formate was detected in the medium.	Methanol	88-96	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	44-48
9226256-3	1997	In a methanol-limited chemostat culture at a low dilution rate (0.03 to 0.05 h[-1]), formate was not detected in the culture medium of the fdh1 delta strain; however, the fdh1 delta strain showed only one-fourth of the growth yield of the wild-type strain.	Methanol	5-13	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	171-175
9226256-4	1997	Expression of FDH1 was found to be induced by choline or methylamine (used as a nitrogen source), as well as by methanol (used as a carbon source).	Methanol	112-120	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	14-18
9219524-3	1997	In the present study, we have investigated the conformation of synthetic secretoneurin in methanol solution by two-dimensional 1H-NMR, circular dichroism and molecular modeling.	Methanol	90-98	secretogranin II	Homo sapiens	73-86
9225723-5	1997	Using a highly sensitive immunostaining technique and a panel of monoclonal and polyclonal antibodies directed against different epitopes of recombinant hTSHR, distinct cytoplasmic hTSHR-like immunoreactivity was detected in methanol-fixed OF and orbital connective tissue, which was absent in abdominal fibroblasts, or when using isotype-matched non-immune immunoglobulins.	Methanol	225-233	thyroid stimulating hormone receptor	Homo sapiens	153-158
9225723-5	1997	Using a highly sensitive immunostaining technique and a panel of monoclonal and polyclonal antibodies directed against different epitopes of recombinant hTSHR, distinct cytoplasmic hTSHR-like immunoreactivity was detected in methanol-fixed OF and orbital connective tissue, which was absent in abdominal fibroblasts, or when using isotype-matched non-immune immunoglobulins.	Methanol	225-233	thyroid stimulating hormone receptor	Homo sapiens	181-186
9294881-1	1997	Exposure of pregnant CD-1 mice to methanol (MeOH) by inhalation on gestation days (gd) 6-15 results in dose-related increases in fetal cleft palate, exencephaly, and skeletal defects.	Methanol	34-42	CD1 antigen complex	Mus musculus	21-25
9294881-1	1997	Exposure of pregnant CD-1 mice to methanol (MeOH) by inhalation on gestation days (gd) 6-15 results in dose-related increases in fetal cleft palate, exencephaly, and skeletal defects.	Methanol	44-48	CD1 antigen complex	Mus musculus	21-25
9160807-0	1997	Influence of methanol and its metabolites on the activity of alpha1-antitrypsin.	Methanol	13-21	serpin family A member 1	Homo sapiens	61-79
9169025-6	1997	Secreted soluble Crry was produced by induction of the AOX1 promoter with methanol.	Methanol	74-82	complement C3b/C4b receptor 1 like	Rattus norvegicus	17-21
9169025-6	1997	Secreted soluble Crry was produced by induction of the AOX1 promoter with methanol.	Methanol	74-82	aldehyde oxidase 1	Rattus norvegicus	55-59
9160807-1	1997	Among methanol and its metabolites, formaldehyde was found to have the strongest inactivating effect on the activity of alpha1-antitrypsin preparation and inhibitor existing in blood serum.	Methanol	6-14	serpin family A member 1	Homo sapiens	120-138
9160807-5	1997	The significant inhibitory effect of methanol on alpha1-antitrypsin appears only at a high concentration of this compound.	Methanol	37-45	serpin family A member 1	Homo sapiens	49-67
9160807-7	1997	In people intoxicated with methanol, alpha1-antitrypsin activity decreases, whereas the content of this inhibitor does not change.	Methanol	27-35	serpin family A member 1	Homo sapiens	37-55
9145214-4	1997	The methanol extract showed significant hepatoprotective activity against CCl4-toxicity in rats and D-galactosamine (D-GalN)/lipopolysaccharide-induced liver injury in mice.	Methanol	4-12	C-C motif chemokine ligand 4	Rattus norvegicus	74-78
9170297-1	1997	A methanol extract of leaves and twigs from Ardisia iwahigensis demonstrated toxicity toward brine shrimp as well as LNCaP, ZR-75-1, and Lu1 human cancer cells in culture.	Methanol	2-10	PDZ domain containing 4	Mus musculus	137-140
9145214-4	1997	The methanol extract showed significant hepatoprotective activity against CCl4-toxicity in rats and D-galactosamine (D-GalN)/lipopolysaccharide-induced liver injury in mice.	Methanol	4-12	galanin and GMAP prepropeptide	Rattus norvegicus	119-123
9145214-5	1997	The methanol extract also significantly protected against CCl4-toxicity in primary cultured rat hepatocytes.	Methanol	4-12	C-C motif chemokine ligand 4	Rattus norvegicus	58-62
9595258-4	1997	Acidic-methanol esterification of free carboxyl groups suppressed the difference in electrophoretic mobility of p19 between tdPH2010 and the wild-type virus.	Methanol	7-15	interleukin 23 subunit alpha	Homo sapiens	112-115
11669711-7	1997	We also show that the quantum yield of the ligand-centered luminescence decreases in the order L(1) > [La(NO(3))(3)(L(1))]MeOH > [La(L(1))(3)](ClO(4))(3).	Methanol	125-129	immunoglobulin kappa variable 1-16	Homo sapiens	119-123
9155741-7	1997	However, when the medium was subjected to organic extraction by the Bligh-Dyer (methanol/chloroform) method and the resulting extract added to equivalent media, embryo-derived PAF was readily degraded by PAF:AH.	Methanol	80-88	patchy fur	Mus musculus	176-179
9155741-7	1997	However, when the medium was subjected to organic extraction by the Bligh-Dyer (methanol/chloroform) method and the resulting extract added to equivalent media, embryo-derived PAF was readily degraded by PAF:AH.	Methanol	80-88	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	Mus musculus	204-210
9030055-5	1997	The detection limit of the microchip MS experiment for myoglobin was found to be lower than 6 x 10(-8) M. Samples in 75% methanol were successfully analyzed with good sensitivity, as were aqueous samples.	Methanol	121-129	myoglobin	Homo sapiens	55-64
11669711-7	1997	We also show that the quantum yield of the ligand-centered luminescence decreases in the order L(1) > [La(NO(3))(3)(L(1))]MeOH > [La(L(1))(3)](ClO(4))(3).	Methanol	125-129	immunoglobulin kappa variable 1-16	Homo sapiens	95-99
11669711-7	1997	We also show that the quantum yield of the ligand-centered luminescence decreases in the order L(1) > [La(NO(3))(3)(L(1))]MeOH > [La(L(1))(3)](ClO(4))(3).	Methanol	125-129	immunoglobulin kappa variable 1-16	Homo sapiens	119-123
9095367-4	1997	The PEO-modified myoglobin, cast on the electrode from water or a methanol solution, showed quasi-reversible redox reactions in PEO (average MW of 400).	Methanol	66-74	myoglobin	Equus caballus	17-26
9095367-6	1997	A clear redox response of the PEO-modified myoglobin was observed after methanol treatment of these layers cast from chloroform or a benzene solution.	Methanol	72-80	myoglobin	Equus caballus	43-52
9113333-4	1997	Determination of the absolute stereochemistry at C-10 as R for 1 is the first example of the direct determination of the absolute stereochemistry of a carbinol position isolated from other functional groups in the annonaceous acetogenins.	Methanol	151-159	homeobox C10	Homo sapiens	49-64
9094741-3	1997	Solvent residence times and radial distribution functions are analyzed around three types of atomic sites (methyl, polar, and positively charged sites) in 1 ns molecular dynamics simulations of the alpha-helical polypeptide SP-C in water, in methanol and in chloroform.	Methanol	242-250	surfactant protein C	Homo sapiens	224-228
9360724-1	1997	Intoxication of rats with methanol (1.5 and 3.0 g/kg body weight) led to a significant, time- and dose-dependent decrease in the activities of cathepsins A, B and C, while the activity of cathepsin D was unaffected.	Methanol	26-34	cathepsin A	Rattus norvegicus	143-164
9360724-1	1997	Intoxication of rats with methanol (1.5 and 3.0 g/kg body weight) led to a significant, time- and dose-dependent decrease in the activities of cathepsins A, B and C, while the activity of cathepsin D was unaffected.	Methanol	26-34	cathepsin D	Rattus norvegicus	188-199
8981040-6	1997	Nicotinamide-adenine dinucleotide phosphate, reduced (NADPH) oxidation was stimulated during interaction of a methanol extract of DEP with the Triton N-101 treated microsomal preparation of mouse lung whereas the cytosolic fraction was less active, suggesting that DEP contains substrates for NADPH-cytochrome P450 reductase (EC 1.6.2.4, P450 reductase) rather than DT-diaphorase.	Methanol	110-118	cytochrome p450 oxidoreductase	Mus musculus	293-324
8981040-6	1997	Nicotinamide-adenine dinucleotide phosphate, reduced (NADPH) oxidation was stimulated during interaction of a methanol extract of DEP with the Triton N-101 treated microsomal preparation of mouse lung whereas the cytosolic fraction was less active, suggesting that DEP contains substrates for NADPH-cytochrome P450 reductase (EC 1.6.2.4, P450 reductase) rather than DT-diaphorase.	Methanol	110-118	NAD(P)H dehydrogenase, quinone 1	Mus musculus	366-379
9122889-0	1996	Influence of maternal folate status on the developmental toxicity of methanol in the CD-1 mouse.	Methanol	69-77	CD1 antigen complex	Mus musculus	85-89
8945907-5	1996	This NO exposure caused a 63 and 70% inhibition of the metabolism by smooth muscle catalase of both endogenously produced and exogenous (100 microM) H2O2, respectively, as measured by the H2O2-dependent cooxidation of methanol to formaldehyde.	Methanol	218-226	catalase	Bos taurus	83-91
8875820-3	1996	Two-dimensional nmr results for ceratotoxin A in methanol show a helical behavior for the 8-25 region of the peptide.	Methanol	49-57	ceratotoxin-A	Ceratitis capitata	32-45
11666793-1	1996	A novel manganese(IV) monomer, [Mn(IV)(Me(3)TACN)(OMe)(3)](PF(6)), has been synthesized in methanol by the reaction of MnCl(2) with the ligand, N,N",N"-trimethyl-1,4,7-triazacyclononane (Me(3)TACN), in the presence of Na(2)O(2).	Methanol	91-99	sperm associated antigen 17	Homo sapiens	59-64
9581474-4	1997	The methanol in 30% concentration reduces catalytic activity of prolidase to 40% of values found in aqueous solution, although it allows in such conditions the measurement of substrate susceptibility to the action of this enzyme.	Methanol	4-12	peptidase D	Homo sapiens	64-73
9646682-0	1997	Ultrastructural evaluation of lysosomes and biochemical changes in cathepsin D distribution in hepatocytes in methanol intoxication.	Methanol	110-118	cathepsin D	Rattus norvegicus	67-78
9490511-4	1997	According to features of the inotropic action the studied agents were divided into two groups: Cth values of the former group were dependent on stimulation frequency (V, methanol, ethanol, isopropanol, chloral hydrate and acetone); Cth values of agents of the latter group were independent on stimulation frequency (n-butanol, n-pentanol, n-hexanol, and chloroform).	Methanol	170-178	V-set and immunoglobulin domain containing 2	Homo sapiens	95-98
8975761-0	1996	Folate and 10-formyltetrahydrofolate dehydrogenase in human and rat retina: relation to methanol toxicity.	Methanol	88-96	aldehyde dehydrogenase 1 family member L1	Homo sapiens	11-50
8901910-3	1996	However, in pure water or methanol SN1 reaction occurs mainly at C-2.	Methanol	26-34	complement C2	Homo sapiens	65-68
8887440-1	1996	A single 6-hr exposure to inhaled methanol (MeOH) has been shown to enhance carbon tetrachloride (CCl4) hepatotoxicity.	Methanol	34-42	C-C motif chemokine ligand 4	Rattus norvegicus	98-102
8887440-1	1996	A single 6-hr exposure to inhaled methanol (MeOH) has been shown to enhance carbon tetrachloride (CCl4) hepatotoxicity.	Methanol	44-48	C-C motif chemokine ligand 4	Rattus norvegicus	98-102
8887440-2	1996	The objective of the present study was to use gas uptake data and the development of a physiologically based pharmacokinetic model (PBPK) to determine in vivo changes in CCl4 metabolism resulting from MeOH pretreatment.	Methanol	201-205	C-C motif chemokine ligand 4	Rattus norvegicus	170-174
8887440-10	1996	Both serum markers of hepatotoxicity in the 24-hr MeOH + CCl4 group increased as a function of CCl4 concentration when compared with 0 ppm CCl4 controls.	Methanol	50-54	C-C motif chemokine ligand 4	Rattus norvegicus	95-99
8887440-10	1996	Both serum markers of hepatotoxicity in the 24-hr MeOH + CCl4 group increased as a function of CCl4 concentration when compared with 0 ppm CCl4 controls.	Methanol	50-54	C-C motif chemokine ligand 4	Rattus norvegicus	95-99
8887440-12	1996	At 100, 250, and 1000 ppm CCl4, ALT and SDH values for the 24-hr MeOH + CCl4 groups were significantly increased relative to control (0 ppm CCl4), CCl4 alone, and 48-hr MeOH + CCl4.	Methanol	65-69	C-C motif chemokine ligand 4	Rattus norvegicus	26-30
8896794-7	1996	The dehydrating (coagulant) fixatives (e.g., ethanol and methanol) preserved immunorecognition of p53 and broad spectrum keratins best while the slow cross-linking fixatives (e.g., unbuffered zinc formalin) were best for demonstrating TGF alpha and p185erbB-2.	Methanol	57-65	tumor protein p53	Homo sapiens	98-101
8887440-12	1996	At 100, 250, and 1000 ppm CCl4, ALT and SDH values for the 24-hr MeOH + CCl4 groups were significantly increased relative to control (0 ppm CCl4), CCl4 alone, and 48-hr MeOH + CCl4.	Methanol	65-69	sorbitol dehydrogenase	Rattus norvegicus	40-43
8887440-13	1996	ALT and SDH levels in the 48-hr MeOH + CCl4 groups were not statistically different from the respective CCl4 alone groups.	Methanol	32-36	sorbitol dehydrogenase	Rattus norvegicus	8-11
8917367-3	1996	The methanol extract of a Brazilian propolis was fractionated by HPLC, and a tumoricidal substance was isolated and characterized as a new clerodane diterpenoid (PMS-1) with a molecular formula of C20H32O3 (MW: 320).	Methanol	4-12	PMS1 homolog 1, mismatch repair system component	Mus musculus	162-167
8814338-2	1996	The PCNA complex formation was detected by PCNA immunostaining following methanol fixation.	Methanol	73-81	proliferating cell nuclear antigen	Homo sapiens	4-8
8919042-10	1996	While methanol fixation enhanced staining of annexin I, it diminished staining of annexin II.	Methanol	6-14	annexin A2	Homo sapiens	82-92
8794803-6	1996	On the other hand, the methanol-fixed specimens stained with proliferating cell nuclear antigen and specimens stained with bromodeoxyuridine showed monophasic peaks in their labeling indices on day 5.	Methanol	23-31	proliferating cell nuclear antigen	Rattus norvegicus	61-95
8794803-7	1996	There was a linear correlation (r = 0.808, P < 0.001) between the labeling index of bromodeoxyuridine and that of methanol-fixed proliferating cell nuclear antigen during the entire experimental period.	Methanol	117-125	proliferating cell nuclear antigen	Rattus norvegicus	132-166
8794803-8	1996	During the regenerating phase, plasma cholecystokinin bioactivity showed positive correlations with the labeling index of bromodeoxyuridine and that of methanol-fixed proliferating cell nuclear antigen, r = 0.555 and 0.566, respectively (P < 0.001).	Methanol	152-160	cholecystokinin	Rattus norvegicus	38-53
8794803-8	1996	During the regenerating phase, plasma cholecystokinin bioactivity showed positive correlations with the labeling index of bromodeoxyuridine and that of methanol-fixed proliferating cell nuclear antigen, r = 0.555 and 0.566, respectively (P < 0.001).	Methanol	152-160	proliferating cell nuclear antigen	Rattus norvegicus	167-201
8794803-9	1996	Immunostaining of methanol-fixed proliferating cell nuclear antigen may be a useful tool for analyzing proliferating acinar cells.	Methanol	18-26	proliferating cell nuclear antigen	Rattus norvegicus	33-67
8660611-4	1996	GSL containing silica gel was scraped off and extracted with chloroform:methanol:water (30:60:8, by vol).	Methanol	72-80	cathepsin A	Homo sapiens	0-3
8814342-1	1996	Evidence to explain the enhanced hepatotoxicity of carbon tetrachloride (CCl4) following methanol exposure by inhalation is presented.	Methanol	89-97	C-C motif chemokine ligand 4	Rattus norvegicus	73-77
8814342-4	1996	In vitro metabolism of CCl4 was also increased in microsomes from methanol-treated animals.	Methanol	66-74	C-C motif chemokine ligand 4	Rattus norvegicus	23-27
8814342-6	1996	This study shows that methanol exposure induces cytochrome P450 2E1, which appears to be the principal toxicokinetic mechanism responsible for the increased metabolism and thus the increased hepatotoxicity of CCl4.	Methanol	22-30	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	48-67
8814342-6	1996	This study shows that methanol exposure induces cytochrome P450 2E1, which appears to be the principal toxicokinetic mechanism responsible for the increased metabolism and thus the increased hepatotoxicity of CCl4.	Methanol	22-30	C-C motif chemokine ligand 4	Rattus norvegicus	209-213
8660947-3	1996	PCNA complex formation was detected by an indirect immunofluorescence method after the cells were fixed in methanol.	Methanol	107-115	proliferating cell nuclear antigen	Homo sapiens	0-4
8897087-1	1996	A diastereomeric mixture of the tripeptide Boc-Ala-Ile-Aib-OMe crystallized in the space group P1 from CH3OH/H2O.	Methanol	103-108	ANIB1	Homo sapiens	55-58
8869791-8	1996	PAF was detected by biological assay after methanol extraction of whole blood or of platelet pellets obtained by sequential centrifugation.	Methanol	43-51	PCNA clamp associated factor	Homo sapiens	0-3
8864660-4	1996	Under conditions of methanol fixation, a significant portion of both hsp90 and the hsp90-associated protein p23 is present on fibrillar structures extending throughout the cytoplasm of endothelial cells, however, when cells are treated with colcemid under conditions that eliminate microtubules, the fibrils condense into bright rope-like bundles located in the immediate perinuclear area and extending toward the cell periphery.	Methanol	20-28	heat shock protein 90 alpha family class A member 1	Rattus norvegicus	69-74
8864660-4	1996	Under conditions of methanol fixation, a significant portion of both hsp90 and the hsp90-associated protein p23 is present on fibrillar structures extending throughout the cytoplasm of endothelial cells, however, when cells are treated with colcemid under conditions that eliminate microtubules, the fibrils condense into bright rope-like bundles located in the immediate perinuclear area and extending toward the cell periphery.	Methanol	20-28	heat shock protein 90 alpha family class A member 1	Rattus norvegicus	83-88
8864660-4	1996	Under conditions of methanol fixation, a significant portion of both hsp90 and the hsp90-associated protein p23 is present on fibrillar structures extending throughout the cytoplasm of endothelial cells, however, when cells are treated with colcemid under conditions that eliminate microtubules, the fibrils condense into bright rope-like bundles located in the immediate perinuclear area and extending toward the cell periphery.	Methanol	20-28	RAS related	Rattus norvegicus	108-111
8844843-3	1996	The Phe 100 Ala substitution has similar effects on the turnover rates of GpC and its minimal analogue GpOMe, in which the leaving cytidine is replaced by methanol.	Methanol	155-163	glycophorin C (Gerbich blood group)	Homo sapiens	74-77
8660611-6	1996	Finally, a stepwise chloroform:methanol gradient chromatography on a small silica gel K60 column was employed to remove non-GSL impurities.	Methanol	31-39	cathepsin A	Homo sapiens	124-127
11667282-6	1996	Thermolysis or photolysis of 8e or9b led via electrocyclic ring opening to a vinyl ketene which was trapped by MeOH, alkenes, dienes, or oxygen to produce polyfunctional unsaturated esters 29 and 30 or 8-membered ring lactone 31, fused cyclobutanones 33 and 34, pyranone 38, or gamma-lactone 39, respectively.	Methanol	111-115	olfactory receptor family 1 subfamily B member 1	Homo sapiens	32-36
8882296-2	1996	Indirect immunofluorescence showed that antibodies to human SP-10 localized to the acrosomal region of methanol-fixed, but not live, bovine spermatozoa, confirming the intra-acrosomal localization of bovine SP-10.	Methanol	103-111	acrosomal vesicle protein 1	Homo sapiens	60-65
8676385-0	1996	The methanol-induced globular and expanded denatured states of cytochrome c: a study by CD fluorescence, NMR and small-angle X-ray scattering.	Methanol	4-12	cytochrome c, somatic	Homo sapiens	63-75
8676385-1	1996	Methanol-induced conformational transitions of cytochrome c(cyt c) at acidic pH values were investigated with a combined use of far and near-UV CD, fluorescence, NMR spectroscopy and small-angle X-ray scattering.	Methanol	0-8	cytochrome c, somatic	Homo sapiens	47-59
8804600-4	1996	In this study, we have used circular dichroism (CD) spectroscopy to examine the binding mechanism and the binding constants (K1 and K2) of cations to gramicidin in the double helical form in methanol solution.	Methanol	191-199	keratin 1	Homo sapiens	125-134
8786367-2	1996	As part of a search for novel inhibitors of endothelin converting enzyme (ECE), the MeOH extract of a South African sponge, Pachastrella sp., was shown to be active.	Methanol	84-88	endothelin converting enzyme 1	Homo sapiens	74-77
11667203-4	1996	Radical reduction with tri-n-butyltin hydride of the appropriate phenoxythiocarbonyl derivative afforded the desired deoxysugar 5 in 47% overall yield together with the secondary products 6 and 7 due to depivaloylation at C-2 and elimination of methanol.	Methanol	245-253	complement C2	Homo sapiens	222-225
11667214-3	1996	Reaction of 2-methyl-endo-tricyclo[3.2.1.0(2,4)]oct-6-ene (2) with bromine in CCl(4) and methanol gave products of reaction at the alkene site.	Methanol	89-97	POU class 3 homeobox 1	Homo sapiens	48-53
8900471-4	1996	In addition, interleukin(IL-)1 alpha is shown to be present in platelet cytoplasm after methanol treatment but not after permeabilization using Fix&Perm.	Methanol	88-96	interleukin 1 alpha	Homo sapiens	13-36
8634247-1	1996	Methanol-induced conformational transitions in cytochrome c have been studied by near- and far-UV circular dichroism, Trp fluorescence, microcalorimetry, and diffusion measurements.	Methanol	0-8	cytochrome c, somatic	Homo sapiens	47-59
8738109-6	1996	The elution profile of methanol extract of the rat retina was identical to that of synthetic TRH.	Methanol	23-31	thyrotropin releasing hormone	Rattus norvegicus	93-96
8669168-8	1996	RESULTS: Freeze substituted cells that were fixed with methanol/ether and stored for more than six months retained strong p53 positivity, as strong as that of the control cells, which had been fixed and stored in methanol.	Methanol	55-63	tumor protein p53	Homo sapiens	122-125
8738021-4	1996	Measurements on the C18 column were made using a gradient of acetonitrile, methanol, and ethyl acetate, which is described in detail elsewhere.	Methanol	75-83	Bardet-Biedl syndrome 9	Homo sapiens	20-23
11666370-2	1996	They are protonated with methanol in en solvent giving [eta(2)-HP(7)M(CO)(4)](2)(-) ions (5) and are alkylated with R(4)N(+) salts in en solutions to give [eta(2)-RP(7)M(CO)(4)](2)(-) complexes (6) in good yields (R = alkyl).	Methanol	25-33	DNA polymerase iota	Homo sapiens	56-62
8601412-3	1996	The affinity purified antibodies have also been used to localize NMT in methanol/acetone permeabilized HeLa cells by immunofluorescent staining.	Methanol	72-80	N-myristoyltransferase 1	Homo sapiens	65-68
11666389-0	1996	Oxidation Kinetics of the Potent Insulin Mimetic Agent Bis(maltolato)oxovanadium(IV) (BMOV) in Water and in Methanol.	Methanol	108-116	insulin	Homo sapiens	33-40
8728322-1	1996	The rabbit cholesteryl ester transfer protein (CETP) was expressed in the methylotrophic yeast Pichia pastoris by introducing the CETP cDNA under the control of the methanol-inducible alcohol oxidase promoter.	Methanol	165-173	cholesteryl ester transfer protein	Oryctolagus cuniculus	11-45
8723438-3	1996	Hexokinase Ab reacted with acrosomal, mid-piece and tail regions of methanol-fixed (approximately 70-80%) and live (approximately 35-52%) sperm in the indirect immunofluorescence technique (IFT) and the immunobead binding technique (IBT), respectively.	Methanol	68-76	hexokinase 1	Homo sapiens	0-10
8728322-1	1996	The rabbit cholesteryl ester transfer protein (CETP) was expressed in the methylotrophic yeast Pichia pastoris by introducing the CETP cDNA under the control of the methanol-inducible alcohol oxidase promoter.	Methanol	165-173	cholesteryl ester transfer protein	Oryctolagus cuniculus	47-51
9020552-4	1996	Activity of superoxide dismutase and catalase was significantly increased after 6 hours following methanol ingestion and persisted up to 2-5 days of intoxication.	Methanol	98-106	catalase	Rattus norvegicus	37-45
23194765-5	1996	Two major isolates from the methanol extract, ginsenosides-Re and -Rgl, showed a significant hepatoprotective effect on D-galactos-amine/lipopolysaccharide-induced liver injury in mice.	Methanol	28-36	ral guanine nucleotide dissociation stimulator,-like 1	Mus musculus	67-70
8868443-0	1996	A protein having similarity with methylmalonyl-CoA mutase is required for the assimilation of methanol and ethanol by Methylobacterium extorquens AM1.	Methanol	94-102	MEXAM1_RS11300	Methylobacterium extorquens AM1	33-57
8822049-5	1996	The activity of TNF alpha induction was mainly found in the methanol-phase, but not in the chloroform-phase, where lipid and glycolipid of the microorganisms were generally thought to be accumulated.	Methanol	60-68	tumor necrosis factor	Homo sapiens	16-25
8835234-0	1995	Comparative toxicokinetics of inhaled methanol in the female CD-1 mouse and Sprague-Dawley rat.	Methanol	38-46	CD1 antigen complex	Mus musculus	61-65
8549771-3	1995	The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source.	Methanol	175-183	Pex3p	Saccharomyces cerevisiae S288C	29-34
8549771-3	1995	The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source.	Methanol	175-183	ion-transporting P-type ATPase SPF1	Saccharomyces cerevisiae S288C	51-56
8549771-3	1995	The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source.	Methanol	175-183	ion-transporting P-type ATPase SPF1	Saccharomyces cerevisiae S288C	51-55
8691642-2	1996	Time course of PCNA staining pattern after hepatectomy in the specimens fixed with 100% methanol or 70% ethanol coincided closely with that of bromodeoxyuridine (BrdU) staining pattern, which is known to be standard marker of cell proliferation.	Methanol	88-96	proliferating cell nuclear antigen	Rattus norvegicus	15-19
8691642-4	1996	These findings suggest that granular immunostaining of PCNA in tissue specimens fixed with 100% methanol, 70% ethanol, 10% BF or 1% PFA is useful for evaluating the extent of cell proliferation.	Methanol	96-104	proliferating cell nuclear antigen	Rattus norvegicus	55-59
8554577-2	1995	A monomeric analogue of phospholamban PLN(C41F), in which Cys41 was replaced by a Phe, was synthesized and its conformation studied by 1H NMR spectroscopy in a 1:1 mixture of chloroform/methanol.	Methanol	186-194	phospholamban	Homo sapiens	38-41
8567176-5	1995	When the reaction mixture, after lyophilisation, was immediately quenched with NH3-saturated dry MeOH, two products could be recovered in a 5:1 ratio, both obtained by nucleophilic attack of the homoserine lactone: the expected [Hse7-NH2]-7,8-seco-ET and [Hse7]ET, resulting from competitive intramolecular reaction of the deprotonated alpha-amino group of the Asp8 residue.	Methanol	97-101	endothelin 1	Homo sapiens	248-250
8567176-5	1995	When the reaction mixture, after lyophilisation, was immediately quenched with NH3-saturated dry MeOH, two products could be recovered in a 5:1 ratio, both obtained by nucleophilic attack of the homoserine lactone: the expected [Hse7-NH2]-7,8-seco-ET and [Hse7]ET, resulting from competitive intramolecular reaction of the deprotonated alpha-amino group of the Asp8 residue.	Methanol	97-101	endothelin 1	Homo sapiens	261-263
7587708-8	1995	The Pgp epitopes remained reactive to the anti-Pgp MAbs after methanol fixation and cryopreservation.	Methanol	62-70	ATP binding cassette subfamily B member 1	Homo sapiens	4-7
7563218-2	1995	Because oral exposure to MeOH potentiates the hepatotoxicity of carbon tetrachloride (CCl4), we examined the ability of inhaled MeOH to potentiate CCl4 hepatotoxicity and the time course of injury and recovery.	Methanol	128-132	C-C motif chemokine ligand 4	Rattus norvegicus	147-151
7563218-8	1995	MeOH+CCl4 resulted in serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) that were increased, relative to CCl4 alone, 171- and 113-fold, respectively, on d 1, and 166- and 140-fold, respectively, on d 1.5.	Methanol	0-4	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	38-64
7563218-8	1995	MeOH+CCl4 resulted in serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) that were increased, relative to CCl4 alone, 171- and 113-fold, respectively, on d 1, and 166- and 140-fold, respectively, on d 1.5.	Methanol	0-4	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	66-69
7563218-8	1995	MeOH+CCl4 resulted in serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) that were increased, relative to CCl4 alone, 171- and 113-fold, respectively, on d 1, and 166- and 140-fold, respectively, on d 1.5.	Methanol	0-4	C-C motif chemokine ligand 4	Rattus norvegicus	139-143
7563218-9	1995	Significant serum elevations in MeOH+CCl4 rats, relative to CCl4 alone rats, were present until d 7 and d 15 for AST and ALT, respectively.	Methanol	32-36	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	113-116
7563218-13	1995	These data demonstrate that inhaled MeOH potentiates the hepatotoxicity of orally ingested CCl4, increasing the severity of CCl4 hepatotoxicity as well as the time required for recovery.	Methanol	36-40	C-C motif chemokine ligand 4	Rattus norvegicus	91-95
7563218-13	1995	These data demonstrate that inhaled MeOH potentiates the hepatotoxicity of orally ingested CCl4, increasing the severity of CCl4 hepatotoxicity as well as the time required for recovery.	Methanol	36-40	C-C motif chemokine ligand 4	Rattus norvegicus	124-128
7559749-4	1995	Selective abolition of these patterns with salt, nuclease, or methanol is associated with liberation of immunoprecipitable proenkephalin into the extraction supernatant.	Methanol	62-70	proenkephalin	Homo sapiens	123-136
8618425-6	1995	Sequential pre-treatment with proteinase-K, methanol and sodium borohydride achieved optimal GFAP localisation.	Methanol	44-52	glial fibrillary acidic protein	Rattus norvegicus	93-97
7623807-9	1995	A factor(s) extracted with methanol-chloroform from transformed membranes or membranes from Sf9 cells coexpressing Ras and SrcY527F significantly enhanced the activity of Raf-1 Y340D or active Raf-1 but not that of inactive Raf-1.	Methanol	27-35	v-raf-leukemia viral oncogene 1	Mus musculus	171-176
7623807-9	1995	A factor(s) extracted with methanol-chloroform from transformed membranes or membranes from Sf9 cells coexpressing Ras and SrcY527F significantly enhanced the activity of Raf-1 Y340D or active Raf-1 but not that of inactive Raf-1.	Methanol	27-35	v-raf-leukemia viral oncogene 1	Mus musculus	193-198
7623807-9	1995	A factor(s) extracted with methanol-chloroform from transformed membranes or membranes from Sf9 cells coexpressing Ras and SrcY527F significantly enhanced the activity of Raf-1 Y340D or active Raf-1 but not that of inactive Raf-1.	Methanol	27-35	v-raf-leukemia viral oncogene 1	Mus musculus	193-198
7548163-3	1995	On the methanol induction, active recombinant PI-6 was produced within the yeast cells, and following cell lysis, was separated from yeast proteins by affinity chromatography using nickel nitrilo-tri-acetic acid (NTA) resin.	Methanol	7-15	serpin family B member 6	Homo sapiens	46-50
7646517-1	1995	Kuwanon G and H, isolated from the methanol extract of Morus bombycis, inhibited specific binding of [125I]gastrin-releasing peptide (GRP) to GRP-preferring receptors in murine Swiss 3T3 fibroblasts with Ki values of 470 and 290 nM, respectively.	Methanol	35-43	gastrin releasing peptide	Mus musculus	134-137
7587708-8	1995	The Pgp epitopes remained reactive to the anti-Pgp MAbs after methanol fixation and cryopreservation.	Methanol	62-70	ATP binding cassette subfamily B member 1	Homo sapiens	47-50
8002620-1	1995	Methanol dehydrogenase, the enzyme that oxidizes methanol to formaldehyde in gram-negative methylotrophs, contains the prosthetic group pyrroloquinoline quinone (PQQ).	Methanol	49-57	MEXAM1_RS09450	Methylobacterium extorquens AM1	0-22
7558598-2	1995	The backbone-modified tripeptide Bz-Aib-NHCOCO-Aib-OMe, in which the central C alpha has been replaced with CO, self-assembles in the solid state into highly ordered two-dimensional arrays through MeOH mediated intermolecular stacking of dimeric "disk" modules formed by an antiparallel beta-sheet-type arrangement of tripeptide molecules.	Methanol	197-201	ANIB1	Homo sapiens	36-39
7558598-2	1995	The backbone-modified tripeptide Bz-Aib-NHCOCO-Aib-OMe, in which the central C alpha has been replaced with CO, self-assembles in the solid state into highly ordered two-dimensional arrays through MeOH mediated intermolecular stacking of dimeric "disk" modules formed by an antiparallel beta-sheet-type arrangement of tripeptide molecules.	Methanol	197-201	ANIB1	Homo sapiens	47-50
7738036-5	1995	Methanol- or oleate-induced cells of per3-1, a mutant strain generated by chemical mutagenesis, lack normal peroxisomes but contain numerous abnormal vesicular structures.	Methanol	0-8	period circadian regulator 3	Homo sapiens	37-41
7656188-3	1995	Methanol, ethanol, n-propanol and n-butanol all induced higher ADH activity in wild-type larvae.	Methanol	0-8	Alcohol dehydrogenase	Drosophila melanogaster	63-66
7795392-2	1995	A fluorogenic reagent, DBPM easily reacted with D- or L-penicillamine to give each two kinds of strong fluorescent derivatives (D1-, D2-, L1- and L2-DBPM), which could be separated on a Pirkle-type chiral stationary phase using an eluent of 75% aqueous methanol solution containing 0.15 M CH3COONH4 and 0.05 M tetra-n-butylammonium bromide.	Methanol	253-261	immunoglobulin kappa variable 3-15	Homo sapiens	146-153
7539747-3	1995	Using indirect immunofluorescence microscopy with brief fixation in methanol (5 sec, -20 degrees C) followed by three dips in acetone (5 sec at room temperature), it became obvious that the intracellular detectability of the proteasomes changes depending on the nutritional and proliferative status of the tumor cells.	Methanol	68-76	BCL2 interacting protein 1	Homo sapiens	80-88
7539747-3	1995	Using indirect immunofluorescence microscopy with brief fixation in methanol (5 sec, -20 degrees C) followed by three dips in acetone (5 sec at room temperature), it became obvious that the intracellular detectability of the proteasomes changes depending on the nutritional and proliferative status of the tumor cells.	Methanol	68-76	BCL2 interacting protein 1	Homo sapiens	80-83
7696560-3	1995	The pentapeptide Boc-Leu-Phe-Ala-delta Phe-Leu-OMe (C39H55N5O8, Mw = 721.9) was crystallized from aqueous methanol.	Methanol	106-114	BOC cell adhesion associated, oncogene regulated	Homo sapiens	17-20
7893842-4	1995	Expression of PCNA in methanol fixed cells with, and without, prior detergent extraction with EDTA/Triton was compared to BrdUrd-labelling index in NIH-3T3 fibroblasts and human Caski tumour cells in exponential phase and under confluent conditions.	Methanol	22-30	proliferating cell nuclear antigen	Homo sapiens	14-18
7596173-10	1995	The PCNA index was measured in cryopreserved, methanol-fixed smears of lymphocytes from patients with various hematological diseases and was compared to the Ki-67 index established independently on a serial sample.	Methanol	46-54	proliferating cell nuclear antigen	Homo sapiens	4-8
7783370-3	1995	The results of several fixation methods demonstrated that formalin and methanol, formalin and ethanol (1:9) and buffered formalin acetone gave good results for detecting p53 protein.	Methanol	71-79	tumor protein p53	Homo sapiens	170-173
7723032-3	1995	Indications of destabilization appear in chloroform during 1 ns while the SP-C alpha-helix is remarkably stable during 1 ns in methanol and water.	Methanol	127-135	surfactant protein C	Homo sapiens	74-78
8540335-1	1995	The human gastric cathepsin E (CTSE) was expressed in the methylotrophic yeast Pichia pastoris by placing the CTSE cDNA under the control of the methanol-inducible alcohol oxidase promoter.	Methanol	145-153	cathepsin E	Homo sapiens	18-29
8540335-1	1995	The human gastric cathepsin E (CTSE) was expressed in the methylotrophic yeast Pichia pastoris by placing the CTSE cDNA under the control of the methanol-inducible alcohol oxidase promoter.	Methanol	145-153	cathepsin E	Homo sapiens	31-35
7770998-4	1995	DNA/cytokeratin-8,18 antibody labelling of methanol-fixed single cells provides a standardized method which is not liable to disturbances and enables use in a routine laboratory.	Methanol	43-51	keratin 8	Homo sapiens	4-17
7999760-0	1994	X-ray spectroscopy of the iron site in soybean lipoxygenase-1: changes in coordination upon oxidation or addition of methanol.	Methanol	117-125	seed linoleate 13S-lipoxygenase-1	Glycine max	47-61
7805869-0	1994	Characterization and determination of the redox properties of the 2[4Fe-4S] ferredoxin from Methanosarcina barkeri strain MS. Ferredoxin was purified from methanol-grown Methanosarcina barkeri strain MS.	Methanol	155-163	4Fe-4S binding protein	Methanosarcina barkeri MS	76-86
7805869-0	1994	Characterization and determination of the redox properties of the 2[4Fe-4S] ferredoxin from Methanosarcina barkeri strain MS. Ferredoxin was purified from methanol-grown Methanosarcina barkeri strain MS.	Methanol	155-163	4Fe-4S binding protein	Methanosarcina barkeri MS	126-136
7999760-4	1994	The coordination of the iron(II) in native lipoxygenase changes when methanol (as low as 0.1%) or glycerol (20%) is added to the buffer prior to freezing.	Methanol	69-77	linoleate 9S-lipoxygenase-4	Glycine max	43-55
7851160-6	1994	Prefixing and holding cells in 50% methanol or 50% ethanol overnight before processing and staining severely depressed PCNA and p120 fluorescence.	Methanol	35-43	proliferating cell nuclear antigen	Homo sapiens	119-123
7827262-3	1994	The compound crystallizes in the monoclinic space group P2(1) from methanol/ethyl acetate.	Methanol	67-75	cyclin dependent kinase inhibitor 1A	Homo sapiens	56-61
7827263-4	1994	The compound crystallizes in the monoclinic space group P2(1) from methanol-dichloromethane solution.	Methanol	67-75	cyclin dependent kinase inhibitor 1A	Homo sapiens	56-61
7851160-6	1994	Prefixing and holding cells in 50% methanol or 50% ethanol overnight before processing and staining severely depressed PCNA and p120 fluorescence.	Methanol	35-43	catenin delta 1	Homo sapiens	128-132
7726999-1	1994	Conformational study of somatostatin and two of its analogues in methanol and in ethylene glycol.	Methanol	65-73	somatostatin	Homo sapiens	24-36
7531528-2	1994	Melittin-TASP and the truncated analogue preferentially adopt alpha-helical structures in methanol (56% and 52%, respectively) as in lipid membranes.	Methanol	90-98	LanC like 2	Homo sapiens	9-13
7826474-1	1994	6-Acetyl-2(3H)-benzoxazolone derivatives were reacted with appropriate piperidine derivatives and formaldehyde in methanol to give the corresponding 6-acyl-3-piperidinomethyl-2(3H)-benzoxazolones.	Methanol	114-122	O-acyltransferase like	Mus musculus	151-157
7884673-8	1994	The fact that the rate of hydrolysis in the methanol:buffer exhibited a first-order dependence on the hydroxide ion concentration and that the rate of hydrolysis increased with increasing methanol concentrations up to 70% supported an SN2 mechanism of hydrolysis for the prodrug.	Methanol	44-52	solute carrier family 38, member 5	Rattus norvegicus	235-238
7884673-8	1994	The fact that the rate of hydrolysis in the methanol:buffer exhibited a first-order dependence on the hydroxide ion concentration and that the rate of hydrolysis increased with increasing methanol concentrations up to 70% supported an SN2 mechanism of hydrolysis for the prodrug.	Methanol	188-196	solute carrier family 38, member 5	Rattus norvegicus	235-238
7524464-1	1994	Immunohistochemical detection of proliferating cell nuclear antigen (PCNA), a cell cycle-related protein used to estimate tumor growth fraction, is variable in formalin-fixed compared with methanol-fixed tissue specimens.	Methanol	189-197	proliferating cell nuclear antigen	Homo sapiens	33-67
7524464-1	1994	Immunohistochemical detection of proliferating cell nuclear antigen (PCNA), a cell cycle-related protein used to estimate tumor growth fraction, is variable in formalin-fixed compared with methanol-fixed tissue specimens.	Methanol	189-197	proliferating cell nuclear antigen	Homo sapiens	69-73
7524464-7	1994	We conclude that the exceptional solubility of PCNA is responsible for reduced immunostaining in formalin-fixed material, that the loss is irreversible, and that methanol or methacarn is the fixative of choice for PCNA immunohistochemistry.	Methanol	162-170	proliferating cell nuclear antigen	Homo sapiens	214-218
17020832-6	1994	In MeOH and TFE, two beta-turn conformations associated with overlapping sequences and cis/trans isomerism at Pro-3 amide bond were seen to be in equilibrium.	Methanol	3-7	pyrroline-5-carboxylate reductase 1	Homo sapiens	110-115
8068618-6	1994	Although the vesicle-bound conformation of melittin is similar to that occurring in a methanol solution and in dodecylphosphocholine micelles, significant differences were found in the conformation of C-terminal basic residues and the helix bend angle.	Methanol	86-94	melittin	Apis mellifera	43-51
7940534-6	1994	The latencies of P1 and N1 peaks of flash-evoked potentials were significantly increased in methanol-challenged FR rats (3.5 g/kg, po), indicating that methanol administration caused an adverse effect in the retinogeniculocortical visual pathway.	Methanol	92-100	perforin 1	Rattus norvegicus	17-26
7940534-6	1994	The latencies of P1 and N1 peaks of flash-evoked potentials were significantly increased in methanol-challenged FR rats (3.5 g/kg, po), indicating that methanol administration caused an adverse effect in the retinogeniculocortical visual pathway.	Methanol	152-160	perforin 1	Rattus norvegicus	17-26
7952008-3	1994	With a DSer-SDS-urea-methanol solution, six phenylthiohydantoin (PTH)DL-amino acids were separated and each enantiomeric pair was optically resolved.	Methanol	21-29	parathyroid hormone	Homo sapiens	65-68
8063750-7	1994	PMP2 encodes a 43-amino acid polypeptide that can be extracted from the membrane with chloroform/methanol.	Methanol	97-105	proteolipid ATPase	Saccharomyces cerevisiae S288C	0-4
8068618-8	1994	In addition, lytic activity of melittin and its analogs showed better correlation with a peptide conformation in vesicles than in either methanol or micelles.	Methanol	137-145	melittin	Apis mellifera	31-39
8003532-1	1994	The human gastric cathepsin E (CTSE), a dimeric aspartic proteinase, was expressed in the methylotrophic yeast Pichia pastoris by placing the CTSE cDNA under the control of the methanol inducible alcohol oxidase promoter.	Methanol	177-185	cathepsin E	Homo sapiens	18-29
7951855-3	1994	PCNA-labelling indices (PCNA-LIs) of methanol-fixed tissues corresponded with the incidence of S-phase cells previously reported, whereas paraformaldehyde-fixed tissues showed extremely high PCNA-LIs in all specimens.	Methanol	37-45	proliferating cell nuclear antigen	Homo sapiens	0-4
7951855-3	1994	PCNA-labelling indices (PCNA-LIs) of methanol-fixed tissues corresponded with the incidence of S-phase cells previously reported, whereas paraformaldehyde-fixed tissues showed extremely high PCNA-LIs in all specimens.	Methanol	37-45	proliferating cell nuclear antigen	Homo sapiens	24-28
7951855-3	1994	PCNA-labelling indices (PCNA-LIs) of methanol-fixed tissues corresponded with the incidence of S-phase cells previously reported, whereas paraformaldehyde-fixed tissues showed extremely high PCNA-LIs in all specimens.	Methanol	37-45	proliferating cell nuclear antigen	Homo sapiens	24-28
7951855-5	1994	The PCNA-LIs of the methanol-fixed tissues were: normal liver 0.78 +/- 0.38%, chronic persistent hepatitis 1.06 +/- 0.86%, chronic aggressive hepatitis 2A 1.01 +/- 0.50%, chronic aggressive hepatitis 2B 4.20 +/- 1.79%, inactive cirrhosis 0.81 +/- 0.49%, active cirrhosis 1.96 +/- 0.93%, HCC of Edmondson"s type I 4.83 +/- 1.98%, type II 6.65 +/- 1.69%, and type III 38.7 +/- 30.6%.	Methanol	20-28	proliferating cell nuclear antigen	Homo sapiens	4-8
7952089-5	1994	Methanol-TFA was found to be the best solvent for extracting 6AM and morphine with minimum hydrolysis and maximum extraction efficiency of 6AM.	Methanol	0-8	coagulation factor III, tissue factor	Homo sapiens	9-12
7952089-6	1994	The extraction rates of 6AM and morphine from heroin abuser"s hair with methanol-TFA reached a plateau after 8-10 h. After the extraction from hair with deuterated internal standards added, the extract was purified by Bond Elut Certify in the usual manner.	Methanol	72-80	coagulation factor III, tissue factor	Homo sapiens	81-84
7913107-4	1994	With five fixation procedures except for acetone/methanol, PCNA was expressed in almost all cells with similar shapes and different FITC intensity levels on PCNA/DNA bivariate cytograms, whereas acetone/methanol fixation allowed PCNA detection in S-phase cells with a cytogram that showed a horseshoe-like pattern with a peak level at mid-S-phase.	Methanol	49-57	proliferating cell nuclear antigen	Homo sapiens	59-63
7913107-5	1994	Flow cytometric dual parameter analysis of PCNA/BrdU was carried out in HeLa cells to confirm detection of PCNA in S-phase cells with acetone/methanol fixation.	Methanol	142-150	proliferating cell nuclear antigen	Homo sapiens	107-111
8003532-1	1994	The human gastric cathepsin E (CTSE), a dimeric aspartic proteinase, was expressed in the methylotrophic yeast Pichia pastoris by placing the CTSE cDNA under the control of the methanol inducible alcohol oxidase promoter.	Methanol	177-185	cathepsin E	Homo sapiens	31-35
8204631-5	1994	The alpha-helical content of the segments, assessed in methanol using circular dichroism, suggests that both the N-terminal and transmembrane segments of IsK adopt alpha-helical structures.	Methanol	55-63	potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog	Xenopus laevis	154-157
8179321-2	1994	Cytochrome b5 increased the rate of oxidation of methanol and/or 7-ethoxycoumarin 2- to 10-fold in both wild type and mutant P450.	Methanol	49-57	cytochrome b5 type A	Homo sapiens	0-13
8076403-6	1994	Treatment of VIII with potassium carbonate in degassed methanol gave I.	Methanol	55-63	cytochrome c oxidase subunit 8A	Homo sapiens	13-17
8074454-2	1994	A Methanol Extraction Residue (MER) of BCG tubercle bacillus induced cytostatic activity in vitro against the murine tumor-cell lines YAC-1 and MOPC-315 in resident murine peritoneal macrophages isolated from BALB/c mice.	Methanol	2-10	ADP-ribosyltransferase 1	Mus musculus	134-139
8181704-2	1994	A total of 32 genes have been reported, termed mox, for methanol oxidation, and it is possible that more will be identified.	Methanol	56-64	monooxygenase DBH like 1	Homo sapiens	47-50
7910934-1	1994	The expression of proliferating cell nuclear antigen (PCNA) was examined in normal human and rat liver fixed in either formaldehyde or methanol, and was compared with the incorporation of bromodeoxyuridine (BrdU) in S-phase cells.	Methanol	135-143	proliferating cell nuclear antigen	Homo sapiens	18-52
7910934-1	1994	The expression of proliferating cell nuclear antigen (PCNA) was examined in normal human and rat liver fixed in either formaldehyde or methanol, and was compared with the incorporation of bromodeoxyuridine (BrdU) in S-phase cells.	Methanol	135-143	proliferating cell nuclear antigen	Homo sapiens	54-58
7910934-10	1994	In methanol-fixed rat liver (n = 10), PCNA LI was 0.14 +/- 0.02% for hepatocytes and 0.40 +/- 0.04% for sinusoidal cells.	Methanol	3-11	proliferating cell nuclear antigen	Rattus norvegicus	38-42
7910934-13	1994	The PCNA LIs and the zonal distribution of labelled nuclei as obtained in methanol-fixed material are in keeping with previous reports using 3H-thymidine (3H-Thy) incorporation, suggesting that PCNA immunostaining represents a valid alternative to 3H-Thy.	Methanol	74-82	proliferating cell nuclear antigen	Rattus norvegicus	194-198
8177023-4	1994	In the second step, "bound" PAF, i.e., PAF not extractable with ethanol, is extracted from the protein precipitate with chloroform/methanol/water.	Methanol	131-139	PCNA clamp associated factor	Homo sapiens	28-31
8177023-4	1994	In the second step, "bound" PAF, i.e., PAF not extractable with ethanol, is extracted from the protein precipitate with chloroform/methanol/water.	Methanol	131-139	PCNA clamp associated factor	Homo sapiens	39-42
8177023-6	1994	"Free" and "bound" PAF are then each fractionated by silicic acid column chromatography, and the methanol/water eluent containing PAF is then further fractionated by high-performance liquid chromatography using an isocratic solvent system of acetonitrile/methanol/water.	Methanol	97-105	PCNA clamp associated factor	Homo sapiens	130-133
8114101-1	1994	The activity of porcine pancreatic phospholipase A2 (pla2), measured at pH 8, is reduced when methanol or ethanol is added to the aqueous solution.	Methanol	94-102	phospholipase A2 group IB	Homo sapiens	35-51
8114101-1	1994	The activity of porcine pancreatic phospholipase A2 (pla2), measured at pH 8, is reduced when methanol or ethanol is added to the aqueous solution.	Methanol	94-102	phospholipase A2 group IB	Homo sapiens	53-57
8179181-2	1994	SP-C was purified from calf lung surfactant extract by gel filtration on LH-20 and LH-60 columns in chloroform:methanol:0.1 N HCl (19:19:2).	Methanol	111-119	surfactant protein C	Bos taurus	0-4
8207074-7	1994	The 92 kDa gelatinase in these co-cultures was released by the fibroblasts; methanol-fixed 2.8 cells induced 92 kDa gelatinase expression in REF, but fixed REF cells did not induce enzyme expression in 2.8 cells.	Methanol	76-84	matrix metallopeptidase 9	Rattus norvegicus	4-21
8207074-7	1994	The 92 kDa gelatinase in these co-cultures was released by the fibroblasts; methanol-fixed 2.8 cells induced 92 kDa gelatinase expression in REF, but fixed REF cells did not induce enzyme expression in 2.8 cells.	Methanol	76-84	matrix metallopeptidase 9	Rattus norvegicus	109-126
7859296-5	1994	Using immunofluorescent cytochemistry, the antibody was used to observe actin filaments in aldehyde-fixed and methanol-treated tobacco protoplasts.	Methanol	110-118	actin	Nicotiana tabacum	72-77
8031242-5	1994	This was not due to inefficient binding of the HTLV-I to the U937 cells, since the methanol-fixed cells were p19 MA protein-positive.	Methanol	83-91	interleukin 23 subunit alpha	Homo sapiens	109-112
8199238-1	1994	To synthesize a glucose-sensitive insulin-releasing protein device, insulin was esterified with methanol and connected to glucose oxidase with intervention of a disulfide compound, 5,5"-dithiobis(2-nitrobenzoic acid).	Methanol	96-104	insulin	Homo sapiens	34-41
8199238-1	1994	To synthesize a glucose-sensitive insulin-releasing protein device, insulin was esterified with methanol and connected to glucose oxidase with intervention of a disulfide compound, 5,5"-dithiobis(2-nitrobenzoic acid).	Methanol	96-104	insulin	Homo sapiens	68-75
8003552-6	1994	The SCX column is then backflushed to a BDS-Hypersil-C18 (5 microns, 250 x 4.6 mm) and eluted with 100 mM acetate pH 4.5-methanol (95:5, v/v) for final separation.	Methanol	121-129	scleraxis bHLH transcription factor	Homo sapiens	4-7
7911757-2	1994	The best fixative for PCNA was found to be buffered formaldehyde solution at 4 degrees C followed by methanol at 20 degrees C, whereas alcoholic fixatives decreased greatly the PCNA immunoreactivity.	Methanol	101-109	proliferating cell nuclear antigen	Homo sapiens	22-26
7909288-5	1994	PC10 with methanol fixation consistently detected higher PCNA positivity in human solid neoplasms than 19F4 and 19A2.	Methanol	10-18	proliferating cell nuclear antigen	Homo sapiens	57-61
7909288-9	1994	The growth fraction by PCNA in solid neoplasms was most reliably determined by PC10 with methanol fixation.	Methanol	89-97	proliferating cell nuclear antigen	Homo sapiens	23-27
7911757-5	1994	PCNA immunoreactivity could be maintained up to 2 mo, putting slides in methanol at -20 degrees C. In conclusion, our report indicates that PCNA is a labile antigen, which may critically be affected by temperature and air-drying procedures.	Methanol	72-80	proliferating cell nuclear antigen	Homo sapiens	140-144
7902738-8	1993	Progesterone was the most potent and abundant compound that inhibited the transporting activity of P-gp among the compounds extracted from bovine adrenal gland with methanol.	Methanol	165-173	phosphoglycolate phosphatase	Bos taurus	99-103
7992463-2	1994	For both cell lines 100% methanol fixation provided optimal fluorescence intensity of PCNA.	Methanol	25-33	proliferating cell nuclear antigen	Homo sapiens	86-90
7624517-1	1994	A monoclonal antibody was raised to a fox sperm protein (FSA-1) which was found to be localized to the inner acrosomal compartment of sperm fixed in methanol.	Methanol	149-157	sperm associated antigen 7	Mus musculus	57-62
8239117-2	1993	We report seven cases, involving four patients, of intentional inhalation of CARB-MEDIC carburetor cleaner containing toluene (43.8%), methanol (23.2%), methylene chloride (20.5%), and propane (12.5%).	Methanol	135-143	syntaxin 8	Homo sapiens	77-81
8301540-2	1993	The methanol extracts of Elephantopi Herba and Lonicerae Flos inhibited the release of intrahepatic enzymes and histological changes by CCl4.	Methanol	4-12	C-C motif chemokine ligand 4	Rattus norvegicus	136-140
7904555-2	1993	The expression of PCNA was evident in almost all cells growing exponentially, when cells were fixed in methanol.	Methanol	103-111	proliferating cell nuclear antigen	Homo sapiens	18-22
8323965-4	1993	Porcine SP-B showed very similar calculated secondary structure when dissolved in methanol, 60% ACN or 70% TFE and reconstituted in lysophosphatidylcholine (LPC) micelles or dipalmitoylphosphatidylcholine (DPPC) vesicles, as deduced from circular dichroism studies.	Methanol	82-90	surfactant protein B	Homo sapiens	8-12
7691667-7	1993	Our results provide direct evidence that the epitopes recognized by the MICA are destroyed by methanol/chloroform treatment but reveal a high stability to Pronase digestion compared to proinsulin epitopes.	Methanol	94-102	MHC class I polypeptide-related sequence A	Homo sapiens	72-76
11540096-2	1993	The 15(3)-14(4) A- CH3OH emission appears to be elongated along the line connecting IRc2 and "the southern condensation (SC)", which may suggest a relation between methanol and the outflow from IRc2.	Methanol	19-24	CD300a molecule	Homo sapiens	84-88
11540096-2	1993	The 15(3)-14(4) A- CH3OH emission appears to be elongated along the line connecting IRc2 and "the southern condensation (SC)", which may suggest a relation between methanol and the outflow from IRc2.	Methanol	19-24	CD300a molecule	Homo sapiens	194-198
11540096-2	1993	The 15(3)-14(4) A- CH3OH emission appears to be elongated along the line connecting IRc2 and "the southern condensation (SC)", which may suggest a relation between methanol and the outflow from IRc2.	Methanol	164-172	CD300a molecule	Homo sapiens	84-88
11540096-2	1993	The 15(3)-14(4) A- CH3OH emission appears to be elongated along the line connecting IRc2 and "the southern condensation (SC)", which may suggest a relation between methanol and the outflow from IRc2.	Methanol	164-172	CD300a molecule	Homo sapiens	194-198
8111230-16	1993	Conformational exchange rates for G1 and G3 were estimated by comparison of the experimental spectra with simulated spectra and found to be as large as 4000 s-1 for G1 in 40% and 15% methanol and 600 s-1 for G3 in 15% methanol.	Methanol	183-191	proline rich protein BstNI subfamily 3	Homo sapiens	34-43
8111230-16	1993	Conformational exchange rates for G1 and G3 were estimated by comparison of the experimental spectra with simulated spectra and found to be as large as 4000 s-1 for G1 in 40% and 15% methanol and 600 s-1 for G3 in 15% methanol.	Methanol	218-226	proline rich protein BstNI subfamily 3	Homo sapiens	34-43
8399396-4	1993	To study the role of the carbohydrate chains of sialyltransferase for enzyme activity, conditions were established in which the native enzyme was deglycosylated with N-Glycanase and endo F. It was found that Glycanase removed the carbohydrate chains from native sialyltransferase, but methanol or ethanol had to be present for rapid and complete deglycosylation.	Methanol	285-293	ST6 beta-galactoside alpha-2,6-sialyltransferase 2	Homo sapiens	48-65
8399396-5	1993	Presence of methanol or ethanol were not essential for removal of carbohydrate chains with endo F. There was a correlation between the loss of catalytic activity of sialyltransferase with increased deglycosylation.	Methanol	12-20	ST6 beta-galactoside alpha-2,6-sialyltransferase 2	Homo sapiens	165-182
8373516-5	1993	In the case of H. polymorpha, TPO expression was achieved when the natural TPO leader sequence was replaced by the MF alpha leader and the construct placed under the control of the methanol-regulated promoter from the methanol oxidase gene.	Methanol	181-189	thyroid peroxidase	Homo sapiens	30-33
8370640-3	1993	2D NMR studies in aqueous MeOH showed the Asn8, Asp8 and isoAsp8 hGRF analogs to have significant alpha-helical character.	Methanol	26-30	growth hormone releasing hormone	Homo sapiens	65-69
8514774-5	1993	The methyl group is not stable on the protein and is lost as [3H]methanol with a half-life of about 180 min at pH 7.0, 37 degrees C. The methyltransferase responsible for this reaction is a cytosolic protein with a native molecular mass of about 40 kDa that is readily separated from the well described protein-L-isoaspartate (D-aspartate) O-methyltransferase (EC 2.1.1.77).	Methanol	65-73	protein-L-isoaspartate (D-aspartate) O-methyltransferase	Bos taurus	303-359
8504082-0	1993	Effect of mutations of ionic amino acids of cytochrome P450 1A2 on catalytic activities toward 7-ethoxycoumarin and methanol.	Methanol	116-124	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	44-63
8400617-7	1993	Thus, the well-known tendency of this region of the GRF peptide to form alpha-helix in isotropic mixed-solvent systems (e.g., methanol/water, trifluoroethanol (TFE)/water) is seen also in SDS/aqueous systems.	Methanol	126-134	growth hormone releasing hormone	Homo sapiens	52-55
8489262-0	1993	Evidence that catalase is a major pathway of ethanol oxidation in vivo: dose-response studies in deer mice using methanol as a selective substrate.	Methanol	113-121	catalase	Mus musculus	14-22
18601259-1	1993	The theoretical yield of poly-D(-)-3-hydroxybutyrate (PHB) has been estimated from the biochemical pathway leading to PHB when a carbohydrate (glucose), a C(1) compound (methanol), a C(2) compound (acetic acid), or a C(4) compound (butyric acid) is used as a carbon source.	Methanol	170-178	prohibitin 1	Homo sapiens	25-52
8458003-3	1993	The condensation of 1,5-anhydro-2,6-dideoxy-D-arabino-hex-1-enitol with methanol in the presence of the phenylbis(phenylthio)sulfonium salt resulted in formation of the first beta-glycoside linkage.	Methanol	72-80	exonuclease 1	Homo sapiens	54-59
8489262-6	1993	In this study, methanol, a selective substrate for catalase in rodents, was compared with ethanol.	Methanol	15-23	catalase	Mus musculus	51-59
8489262-12	1993	The catalase inhibitor aminotriazole decreased ethanol and methanol metabolism 75% in ADH- deer mice.	Methanol	59-67	catalase	Mus musculus	4-12
18601259-1	1993	The theoretical yield of poly-D(-)-3-hydroxybutyrate (PHB) has been estimated from the biochemical pathway leading to PHB when a carbohydrate (glucose), a C(1) compound (methanol), a C(2) compound (acetic acid), or a C(4) compound (butyric acid) is used as a carbon source.	Methanol	170-178	prohibitin 1	Homo sapiens	54-57
8434128-2	1993	Dimethylsulfoxide (DMSO), dimethylformamide, dimethyl-acetamide, ethanol, and methanol all reduced NAT II activity in concentrations ranging from 1.25 to 10%.	Methanol	78-86	N-acetyltransferase 1	Rattus norvegicus	99-102
8273564-3	1993	This improved assay uses purified human MMP-3 in the presence of either 5% methanol or 5% DMSO.	Methanol	75-83	matrix metallopeptidase 3	Homo sapiens	40-45
8273564-5	1993	We have determined a Km of 39.2 microM and Kcat/Km of 4.6 microM/h for MMP-3 (in 5% MeOH) using this peptide substrate.	Methanol	84-88	matrix metallopeptidase 3	Homo sapiens	71-76
8423764-11	1993	Inhibition of methanol metabolism in deer mice expressing ADH indicates that this phenomenon also occurs in species with ADH.	Methanol	14-22	aldo-keto reductase family 1, member A1 (aldehyde reductase)	Mus musculus	58-61
8423764-11	1993	Inhibition of methanol metabolism in deer mice expressing ADH indicates that this phenomenon also occurs in species with ADH.	Methanol	14-22	aldo-keto reductase family 1, member A1 (aldehyde reductase)	Mus musculus	121-124
27314787-7	1993	The addition of H2O2 and catalase to the reaction system supplied molecular oxygen for methanol oxidation to formaldehyde by alcohol oxidase.	Methanol	87-95	catalase	Homo sapiens	16-33
8220581-10	1993	The c-myc specific DNA probe reacted with the postacrosomal mid-piece and tail regions of both noncapacitated as well as capacitated methanol-fixed sperm cells.	Methanol	133-141	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	4-9
8426272-10	1993	The 100% CHC1(3) eluate proved to be the most toxic (mouse killed in 32 minutes) and the 10% MeOH-CHC1(3) fraction killed in approximately 48 hours.	Methanol	93-97	regulator of chromosome condensation 1	Mus musculus	98-102
1332612-2	1992	Fractionation of organic extracts by thin layer chromatography in chloroform/acetone/methanol/acetic acid/water (50/20/10/10/5, v/v) revealed two insulin-sensitive glucosaminyl lipid fractions, the TLC origin (the Rf 0.0 fraction) and a fraction that migrated with Rf 0.18-0.2 (the Rf 0.2 fraction).	Methanol	85-93	insulin	Homo sapiens	146-153
1459992-4	1992	Organic solvents, such as dimethyl sulfoxide and methanol, and the presence of sarcoplasmic reticulum membranes produces an alteration of the denaturation thermogram of glycogen phosphorylase b similar to that produced by the above-mentioned detergents.	Methanol	49-57	glycogen phosphorylase B	Homo sapiens	169-193
21554653-3	1992	The water-soluble fraction of rat milk (infranatant, prepared by ultracentrifugation) and its methanol/acetic acid extract (milk-borne peptides) stimulated GH release from perifused pituitary glands obtained from 2-day-old rats.	Methanol	94-102	gonadotropin releasing hormone receptor	Rattus norvegicus	156-158
1417867-2	1992	To find out the molecular basis for this important feature of BvR mechanism, helical and extended biliverdins were titrated for their acid-base equilibria in a protic solvent (methanol).	Methanol	176-184	biliverdin reductase A	Homo sapiens	62-65
1483839-2	1992	The conformation of pituitary adenylate cyclase activating polypeptide with 27 residues (PACAP27) has been determined by two-dimensional NMR and CD spectroscopies and distance geometry in 25% methanol.	Methanol	192-200	adenylate cyclase activating polypeptide 1	Homo sapiens	20-70
1415320-5	1992	The methanol:saline phase was separated and lyophilized to yield the SP-A product.	Methanol	4-12	surfactant protein A1	Homo sapiens	69-73
1445672-2	1992	Conversion of ap-9-pivaloylfluorene, ap-(I), into lithiated (I)-9-anion followed by the addition of MeOH, then H2O, led to unexpected hydroxylation to provide 20-40% of sp-9-hydroxy-9-pivaloyfluorene, sp-(II), and 60-80% recovery of ap-(I).	Methanol	100-104	Sp9 transcription factor	Homo sapiens	169-173
1445672-2	1992	Conversion of ap-9-pivaloylfluorene, ap-(I), into lithiated (I)-9-anion followed by the addition of MeOH, then H2O, led to unexpected hydroxylation to provide 20-40% of sp-9-hydroxy-9-pivaloyfluorene, sp-(II), and 60-80% recovery of ap-(I).	Methanol	100-104	integrin binding sialoprotein	Homo sapiens	201-207
1385560-6	1992	CBP was isolated from proteins precipitated from bile by CaCl2, as well as from the calcium bilirubinate shells of cholesterol gallstones, by extraction successively with methyl-t-butyl ether, methanol, and Na2EDTA, followed by Sephadex G-25 chromatography and two-stage preparative SDS-PAGE.	Methanol	193-201	CREB binding protein	Homo sapiens	0-3
1291487-0	1992	Acetylcholine and cholinesterase levels in the brain of methanol treated rats.	Methanol	56-64	butyrylcholinesterase	Rattus norvegicus	18-32
1354671-2	1992	Immunofluorescence staining after methanol fixation was used to detect the PCNA complex formation.	Methanol	34-42	proliferating cell nuclear antigen	Homo sapiens	75-79
1329094-1	1992	Temperature dependence of the thermodynamics of folding/unfolding for cytochrome c has been determined as a function of moderate [0-10% (vol/vol)] concentrations of methanol.	Methanol	165-173	cytochrome c, somatic	Homo sapiens	70-82
1441760-2	1992	Aflatoxins B1, B2, G1, and G2, are extracted by methanol/water (85 + 15) and partitioned into methylene dichloride.	Methanol	48-56	anthocyanin regulatory R-S protein-like	Zea mays	11-29
1506429-2	1992	The v-H-ras monoclonal antibody (mAb) against the c-ras protein, p21, reacted specifically with the acrosomal region of methanol-fixed as well as unfixed-live capacitated and non-capacitated human sperm cell in the indirect immunofluorescence technique.	Methanol	120-128	H3 histone pseudogene 16	Homo sapiens	65-68
18965507-2	1992	The rate constant of the following chemical step, methyl radical cleavage, was measured by double potential step chronoamperometry to be 590 sec(-1) in a solvent mixture (DMF 40%, methanol 60%, at -30 degrees ).	Methanol	180-188	secretory blood group 1, pseudogene	Homo sapiens	141-147
1353458-2	1992	PCNA complex formation was detected by the immunofluorescence method after methanol fixation and nucleotide excision repair activity was detected as the unscheduled DNA synthesis (UDS) by autoradiography labeled with [3H]thymidine.	Methanol	75-83	proliferating cell nuclear antigen	Homo sapiens	0-4
1616060-5	1992	SP-B partitioned into chloroform-methanol, which was evaporated under N2.	Methanol	33-41	surfactant protein B	Bos taurus	0-4
31849371-8	1992	A similar value of r 0   0.50 was obtained from the frequency-domain anisotropy data with two-photon excitation of PPO in methanol, butanol, and propylene glycol at 20  C. These higher values of r 0 indicate that two-photon excitation results in a more highly oriented photoselected population, which can increase the resolution of rotational correlation times and/or complex anisotropy decays.	Methanol	122-130	protoporphyrinogen oxidase	Homo sapiens	115-118
1400735-2	1992	The method is very simple as sample preparation is minimal, and the isocratic elution of the C18 column with pure methanol does not necessitate a sophisticated instrumental set-up.	Methanol	114-122	Bardet-Biedl syndrome 9	Homo sapiens	93-96
1317125-4	1992	Reversed-phase HPLC of the partially purified methanol extract showed that greater than 75% of the ANG I- and greater than 82% of the ANG II-like immunoreactivity coeluted with ANG I and II, respectively.	Methanol	46-54	angiotensinogen	Rattus norvegicus	134-140
1317125-4	1992	Reversed-phase HPLC of the partially purified methanol extract showed that greater than 75% of the ANG I- and greater than 82% of the ANG II-like immunoreactivity coeluted with ANG I and II, respectively.	Methanol	46-54	angiotensinogen	Rattus norvegicus	177-189
1477118-7	1992	Optimal transfer of the TGF-beta 2 protein was achieved on PVDF membrane with semi-dry transfer for 4 h at 9 V, using 10 mM CAPS, pH 11.0, containing 5% methanol as transfer buffer.	Methanol	153-161	transforming growth factor beta 2	Homo sapiens	24-34
1387649-5	1992	C18 (5 microns) column with a mobile phase consisting of methanol-phosphate buffer (pH 7.4) (70:30, v/v) was used.	Methanol	57-65	Bardet-Biedl syndrome 9	Homo sapiens	0-3
16668783-5	1992	VM 23 was partially extracted from the vacuolar membranes with chloroform:methanol, indicating its high hydrophobicity.	Methanol	74-82	aquaporin TIP1-2-like	Raphanus sativus	0-5
1804104-4	1991	Endogenous digitalis like factor(s) absorbed to Sepharose coupled to Fab fragments can be eluted by methanol.	Methanol	100-108	FA complementation group B	Homo sapiens	69-72
1639122-6	1992	The elution profile of methanol-extract of the rat retina was identical to that of synthetic TRH.	Methanol	23-31	thyrotropin releasing hormone	Rattus norvegicus	93-96
1417071-2	1992	Under methanol fixation, cyclin immunostaining might serve as a specific marker for S-phase cells.	Methanol	6-14	proliferating cell nuclear antigen	Homo sapiens	25-31
1759707-2	1991	The chelate is separated on C18-bonded silica packing by using an aqueous methanol mobile phase containing tetrabutylammonium bromide and is detected with 0.005 AU full-scale at 510 nm.	Methanol	74-82	Bardet-Biedl syndrome 9	Homo sapiens	28-31
1819701-1	1991	Approximately 75% of the PAF present in saliva is recovered on extraction of whole saliva (0.8 vol) with chloroform/methanol/water (2:2:1, v/v/v).	Methanol	116-124	PCNA clamp associated factor	Homo sapiens	25-28
1656888-3	1991	Addition of ethanol or methanol produced additional hyperfine splittings due to the respective hydroxyalkyl radical adducts, indicating the presence of free.OH.DMPO/.OH formation was not significantly inhibited by Desferal, catalase, or superoxide dismutase (SOD).	Methanol	23-31	superoxide dismutase 1	Homo sapiens	237-257
1656888-3	1991	Addition of ethanol or methanol produced additional hyperfine splittings due to the respective hydroxyalkyl radical adducts, indicating the presence of free.OH.DMPO/.OH formation was not significantly inhibited by Desferal, catalase, or superoxide dismutase (SOD).	Methanol	23-31	superoxide dismutase 1	Homo sapiens	259-262
1815230-1	1991	A 41 amino acid peptide, probably identical in structure to human corticotropin releasing factor, was isolated from 70 equine hypothalami by methanol extraction, immunoaffinity chromatography and single step of reverse phase HPLC.	Methanol	141-149	corticotropin releasing hormone	Homo sapiens	66-96
1759354-1	1991	The studies of peculiarities of aliphatic alcohol metabolism in etiopathogenesis of acute poisoning with methyl alcohol and ethilenglicol have shown that it was reasonable to apply the inhibitors of alcoholdehydrogenase as a specific antidote in emergency therapy.	Methanol	105-119	aldo-keto reductase family 1 member A1	Homo sapiens	199-219
1770353-1	1991	Alcohol oxidase, a major peroxisomal protein of methanol-utilizing yeasts, may possess two different forms of flavin adenine dinucleotide, classical FAD and so-called modified FAD (mFAD).	Methanol	48-56	Fanconi anemia, complementation group D2	Mus musculus	181-185
1770353-4	1991	The presence of mFAD led to a slight decrease in Vmax and a significant (about one order) decrease in the Km of alcohol oxidase with respect to methanol.	Methanol	144-152	Fanconi anemia, complementation group D2	Mus musculus	16-20
1798788-2	1991	However, subchronic pretreatment with oral doses of the MeOH extract of either the underground part of Notopterygium incisum or that of N. forbesii appreciably suppressed the formation of CCl4-induced lipid peroxidation products.	Methanol	56-60	chemokine (C-C motif) ligand 4	Mus musculus	188-192
1812278-4	1991	As previously reported, the methanol extract from the bark of AN and the fractions of the methanol extract have protective effects for liver injury induced by carbon tetrachloride (CCl4) in rats.	Methanol	28-36	C-C motif chemokine ligand 4	Rattus norvegicus	181-185
1812278-4	1991	As previously reported, the methanol extract from the bark of AN and the fractions of the methanol extract have protective effects for liver injury induced by carbon tetrachloride (CCl4) in rats.	Methanol	90-98	C-C motif chemokine ligand 4	Rattus norvegicus	181-185
1812278-6	1991	The active principles for the protection of CCl4-induced liver injury were recognized in a fraction (EF 3-3) obtained by using silica gel chromatography (solvent: CHCl3-MeOH-H2O).	Methanol	169-173	C-C motif chemokine ligand 4	Rattus norvegicus	44-48
1776157-3	1991	Testes isolated from methanol-exposed (200 ppm) rats had the same capability as those from air-exposed rats in synthesizing testosterone whether testes were incubated in the absence or presence of hCG.	Methanol	21-29	hypertrichosis 2 (generalised, congenital)	Homo sapiens	197-200
1655380-8	1991	The following rate constants at 298 K have been measured (liter mol-1 sec-1): kOH (isopropanol) = 2.7 x 10(9) (relative to kOH (methanol) = 8.46 x 10(9]; kOH (toluene) = 6.0 x 10(9); and kOH (p-xylene) = 4.5 x 10(9) (relative to kOH (benzene) = 7.8 x 10(9].	Methanol	128-136	secretory blood group 1, pseudogene	Homo sapiens	70-75
1777966-5	1991	Extraction of saliva with chloroform/methanol/water resulted in 70-90% recovery of PAF.	Methanol	37-45	PCNA clamp associated factor	Homo sapiens	83-86
1898039-4	1991	In addition, rates of metabolism of methanol, a selective substrate for catalase in rodents, were similar to rates of ethanol elimination and were decreased from 6.9 +/- 1.0 to 1.7 +/- 0.5 mmol/kg/h by fructose, supporting the hypothesis that catalase and not a mitochondrial dehydrogenase predominates in ethanol oxidation in ADH-deer mice.	Methanol	36-44	catalase	Mus musculus	72-80
1898039-4	1991	In addition, rates of metabolism of methanol, a selective substrate for catalase in rodents, were similar to rates of ethanol elimination and were decreased from 6.9 +/- 1.0 to 1.7 +/- 0.5 mmol/kg/h by fructose, supporting the hypothesis that catalase and not a mitochondrial dehydrogenase predominates in ethanol oxidation in ADH-deer mice.	Methanol	36-44	catalase	Mus musculus	243-251
1884242-3	1991	PC12 cells treated with a suboptimal concentration of NGF (30 ng/ml) and an alcohol (87 mM) underwent rapid morphological differentiation which was dependent upon the side chain length of the alcohol MeOH less than EtOH less than PrOH less than BuOH.	Methanol	200-204	nerve growth factor	Rattus norvegicus	54-57
1910297-4	1991	By feeding alcohols simultaneously with 3AT, ethanol and methanol were shown to react efficiently with catalase in wild-type larvae at moderately low dietary concentrations.	Methanol	57-65	Catalase	Drosophila melanogaster	103-111
1934177-1	1991	Identification of Ca2+ channel antagonistic compound from the methanol extract.	Methanol	62-70	carbonic anhydrase 2	Canis lupus familiaris	18-21
1917311-1	1991	Two-dimensional HOHAHA and ROESY nuclear magnetic resonance techniques are used to obtain complete proton resonance assignments and to perform a conformational investigation of the neuropeptide neurotensin (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu) in aqueous solution, methanol, and membrane-mimetic [deuterated sodium dodecylsulfate (SDS)] environments.	Methanol	282-290	neurotensin	Homo sapiens	194-205
1947439-3	1991	It was found that PDT has a significantly higher affinity than ET or BAL for phenyldichloroarsine (PDA) in methanol.	Methanol	107-115	poly(ADP-ribose) polymerase family member 9	Homo sapiens	69-72
1910297-6	1991	Catalase apparently represents a minor pathway for ethanol degradation in D. melanogaster larvae, but it may be an important route for methanol elimination from D. melanogaster larvae.	Methanol	135-143	Catalase	Drosophila melanogaster	0-8
1910018-0	1991	Transesterification of Moz-Asn-Leu-Gly-OEt in methanol.	Methanol	46-54	lysine acetyltransferase 6A	Homo sapiens	23-26
1917300-2	1991	Only Z-Asn-Leu-Gly-OEt and Moz-Gln-Leu-Gly-OEt were transesterified in methanol, indicating the existence of a peptide derivative-Ca2+ catalytic complex that may favor the reaction.	Methanol	71-79	lysine acetyltransferase 6A	Homo sapiens	27-30
1680623-9	1991	When TRA or TRC was a substrate, two products, MA1 (the major product) and MA2 from TRA, and one product, MC from TRC, were, respectively, detected in the methanol extract.	Methanol	155-163	Activity QTL 1	Rattus norvegicus	47-50
1910018-2	1991	During the recrystallization of the crude protected tripeptide ester Moz-Asn-Leu-Gly-OEt (obtained by an enzymatic coupling reaction) in methanol/water, the transesterification of this compound to methyl ester was observed.	Methanol	137-145	lysine acetyltransferase 6A	Homo sapiens	69-72
1910018-4	1991	After recrystallization Moz-Asn-Leu-Gly-OEt lost the ability to be transesterified in methanol.	Methanol	86-94	lysine acetyltransferase 6A	Homo sapiens	24-27
1910018-3	1991	The involvement of Ca2+ in this process was indicated by the results obtained in the following experiments: 1) incubation of crude Moz-Asn-Leu-Gly-OEt in methanol solutions of o-phenanthroline and EDTA; 2) recrystallization of the crude Moz-Asn-Leu-Gly-OEt in ethanol/water followed by incubation in methanol; 3) determination of the Ca2+ content of the crude Moz-Asn-Leu-Gly-OEt.	Methanol	154-162	lysine acetyltransferase 6A	Homo sapiens	131-134
1910018-3	1991	The involvement of Ca2+ in this process was indicated by the results obtained in the following experiments: 1) incubation of crude Moz-Asn-Leu-Gly-OEt in methanol solutions of o-phenanthroline and EDTA; 2) recrystallization of the crude Moz-Asn-Leu-Gly-OEt in ethanol/water followed by incubation in methanol; 3) determination of the Ca2+ content of the crude Moz-Asn-Leu-Gly-OEt.	Methanol	300-308	lysine acetyltransferase 6A	Homo sapiens	131-134
2074541-3	1990	Among them methanol extracts of Caryophylli Flos, Angelicae Dahuricae Radix, Polygoni Avicularis Herba, Myricae Cortex and Forsythiae Fructus were newly found to have protective effects against acute hepatic injury induced by CCl4.	Methanol	11-19	C-C motif chemokine ligand 4	Rattus norvegicus	226-230
24242175-3	1991	With a mobile phase consisting of methanol/water/triethanolamine (80:20:0.5, v/v/w), flow injection frit-FAB analysis of oligonucleotides showed lower limits of detection compared to standard probe FAB mass spectrometry.	Methanol	34-42	FA complementation group B	Homo sapiens	105-108
24242175-3	1991	With a mobile phase consisting of methanol/water/triethanolamine (80:20:0.5, v/v/w), flow injection frit-FAB analysis of oligonucleotides showed lower limits of detection compared to standard probe FAB mass spectrometry.	Methanol	34-42	FA complementation group B	Homo sapiens	198-201
24242175-8	1991	Finally, frit-FAB liquid chromatography mass spectrometry was demonstrated by separating mixtures of oligonucleotides on a beta -cyclodextrin high-performance liquid chromatography column with a mobile phase containing methanol, water, and triethanolamine.	Methanol	219-227	FA complementation group B	Homo sapiens	14-17
1666528-3	1991	Results are presented in which hydrogen-exchange electrospray-ionization mass spectrometry is used to probe conformational changes in bovine ubiquitin induced by the addition of methanol to aqueous acidic solutions of the protein.	Methanol	178-186	ubiquitin	Bos taurus	141-150
1776249-2	1991	Endogenously formed or consumed methanol is almost exclusively metabolized by alcohol dehydrogenase.	Methanol	32-40	aldo-keto reductase family 1 member A1	Homo sapiens	78-99
2053487-0	1991	Kinetics and mechanism of methanol and formaldehyde interconversion and formaldehyde oxidation catalyzed by liver alcohol dehydrogenase.	Methanol	26-34	aldo-keto reductase family 1 member A1	Homo sapiens	114-135
1940202-1	1991	Recently, we have reported that several nonacid agents including phenylpentol, methanol extract of licorice root (FM 100), plaunotol, and teprenon stimulate release of endogenous secretin in humans, dogs, and rats.	Methanol	79-87	secretin	Homo sapiens	179-187
2083274-1	1990	Interaction of alcohols (methanol, glycerol, sorbitol) with human serum albumin (HSA) was studied by the use of NMR spectroscopy in frozen aqueous solutions.	Methanol	25-33	albumin	Homo sapiens	66-79
2281929-2	1990	Rapid solid phase extraction of 2 mL of urine using octadecylsilane cartridges (Bond Elut C18) concentrates compounds of interest (including the polar metabolite of cocaine, benzoylecgonine), in a small volume of methanol, which is easily dried down.	Methanol	213-221	Bardet-Biedl syndrome 9	Homo sapiens	90-93
1696624-1	1990	Myelin basic protein (MBP) from the Whaler shark (Carcharhinus obscurus) has been purified from acid extracts of a chloroform/methanol pellet from whole brains.	Methanol	126-134	myelin basic protein	Bos taurus	22-25
2385242-5	1990	Characterization of the product of the interaction of methanol and 2,4-DAT indicated that methanol is activated to a reactive intermediate, probably formaldehyde, by the 9000 X g supernatant used in the Ames/Salmonella assay.	Methanol	90-98	solute carrier family 6 member 3	Rattus norvegicus	71-74
2134197-3	1990	The LC/TSP-MS spectra showed quasi-molecular ions [M + H]+ at m/z 146 and m/z 160 for the methanol-derived and ethanol-derived radical adducts, respectively, and an apparent molecular ion M+ at m/z 130 for the hydroxyl radical adduct.	Methanol	90-98	thrombospondin 1	Homo sapiens	7-10
2406266-9	1990	CD studies provided evidence that histatin 5 and the longer fragments, C16, N16, and C14 preferred alpha-helical conformations in non-aqueous solvents such as trifluoroethanol and methanol, while in water and pH 7.4 phosphate buffers, they favored random coil structures.	Methanol	180-188	histatin 3	Homo sapiens	34-44
2104489-6	1990	Extracted by CHCl3:CH3OH:H2O (2:2:1.8), separated by thin layer chromatography (TLC) and determined by liquid scintillation counting, PAF released was inhibited significantly by Dau both in time (10-30 min) and dose (1-1000 mumol/L) dependent manners.	Methanol	19-24	patchy fur	Mus musculus	134-137
2203302-1	1990	A new reversed-phase high-pressure liquid chromatography assay procedure for dihydropteroate synthetase (DHPS) that involves the elution of the enzyme incubation solution with a series of three solvents of decreasing polarity (ammonium phosphate buffer, 10% methanol, and 50% methanol) was designed.	Methanol	258-266	dihydropteroate synthetase	Escherichia coli	105-109
2203302-1	1990	A new reversed-phase high-pressure liquid chromatography assay procedure for dihydropteroate synthetase (DHPS) that involves the elution of the enzyme incubation solution with a series of three solvents of decreasing polarity (ammonium phosphate buffer, 10% methanol, and 50% methanol) was designed.	Methanol	276-284	dihydropteroate synthetase	Escherichia coli	105-109
2229016-7	1990	In order to obtain mass spectra and mass chromatograms of individual components, effluent from the HPLC column was mixed with a methanol solution of triethanolamine, which was used as the matrix for the FAB ionization, and one-thirtieth of the effluent mixture was introduced into a mass spectrometer through a frit interface.	Methanol	128-136	FA complementation group B	Homo sapiens	203-206
2394999-5	1990	Conductometric and potentiometric studies in methanol, for d10 metal-sulphonylurea complexes, demonstrated that zinc, cadmium and silver complexes are 1:1 electrolytes and are protonated in the range 4.2-5.6 pH.	Methanol	45-53	CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion	Homo sapiens	59-62
2295642-1	1990	Alcohol metabolism via alcohol dehydrogenase (ADH) and catalase was studied in perfused rat livers by measuring the oxidation of methanol and butanol, selective substrates for catalase and ADH, respectively.	Methanol	129-137	alcohol dehydrogenase 1C (class I), gamma polypeptide	Rattus norvegicus	46-49
1691766-2	1990	Brief exposure of cells to methanol, ethanol, 2-propanol, or butanol resulted in the production of an acid-labile IFN which could be detected in the supernatant medium as early as 60 min after removal of the drug.	Methanol	27-35	interferon	Gallus gallus	114-117
1689289-7	1990	SP forms between 10 and 30% (1-3 residues) helical structure in sodium dodecyl sulfate micelles and less than 10% helix in methanol and trifluoroethanol.	Methanol	123-131	tachykinin precursor 1	Homo sapiens	0-2
2295642-1	1990	Alcohol metabolism via alcohol dehydrogenase (ADH) and catalase was studied in perfused rat livers by measuring the oxidation of methanol and butanol, selective substrates for catalase and ADH, respectively.	Methanol	129-137	catalase	Rattus norvegicus	55-63
2295642-4	1990	Both effects of butanol were blocked by an inhibitor of ADH, 4-methylpyrazole, consistent with the hypothesis that elevation of the NADH redox state by butanol inhibited H2O2 production via NAD+-requiring peroxisomal beta-oxidation, leading indirectly to diminished rates of catalase-dependent methanol uptake.	Methanol	294-302	alcohol dehydrogenase 1C (class I), gamma polypeptide	Rattus norvegicus	56-59
33812129-7	2021	Catalytic studies showed that the Ag-TiO2/RGO photocathode possessed a remarkable PEC CO2 reduction activity and selective production of CH3OH with a yield of 85 mumol L-1 cm-2, the quantum efficiency of 20% and Faradic efficiency of 60.5% at onset potential of -0.7 V. A plausible PEC CO2 reduction mechanism over Ag-TiO2/RGO photocathode is schematically demonstrated.	Methanol	137-142	L1 cell adhesion molecule	Homo sapiens	168-176
2097283-0	1990	[Spectral interactions of cytochrome P-450 with n-heptane and methanol].	Methanol	62-70	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	26-42
2097283-1	1990	Methanol interacts with cytochrome P-450 to produce the reversed type I spectral change.	Methanol	0-8	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	24-40
2097283-2	1990	In the presence of type I substrate n-heptane, the methanol induced spectrum disappears without detectable effects of interaction suggesting that methanol is a very weak ligand for heme iron of cytochrome P-450.	Methanol	51-59	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	194-210
2097283-2	1990	In the presence of type I substrate n-heptane, the methanol induced spectrum disappears without detectable effects of interaction suggesting that methanol is a very weak ligand for heme iron of cytochrome P-450.	Methanol	146-154	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	194-210
2097283-3	1990	Methanol strongly lowers the apparent spectral dissociation constant (Ks app) of n-heptane binding with rat liver cytochrome P-450 both in control and C6-C9 petroleum fraction inhaled group.	Methanol	0-8	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	114-130
2165991-1	1990	Spin-label nitroxyl derivatives of tetramethylpyrroline and tetramethylpyrrolidine in frozen solutions of perdeuterated methanol have been characterized by electron nucleus double resonance (ENDOR spectroscopy).	Methanol	120-128	spindlin 1	Homo sapiens	0-4
2129307-5	1990	The results indicate the peroxidative activity of catalase plays the major role in the methanol metabolism in mice.	Methanol	87-95	catalase	Mus musculus	50-58
33970624-1	2021	Using UV-vis and resonance Raman spectroscopy, we identify a [Cu2O]2+ active site in O2 and N2O activated Cu-CHA that reacts with methane to form methanol at low temperature.	Methanol	146-154	transcription factor like 5	Homo sapiens	109-112
33825397-2	2021	METHODS: Maximal non-toxic dose (MNTD) of methanol extract of P. ginseng root culture on BV2 microglia cells was first determined via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, followed by treatment and LPS stimulation of cells, and the measurement of NO using Griess assay and TNF-alpha, IL-6, and IL-10 using ELISA assay.	Methanol	42-50	interleukin 6	Mus musculus	314-318
33771930-0	2021	Methanol sensor Wsc1 and MAP kinase suppress degradation of methanol-induced peroxisomes in methylotrophic yeast.	Methanol	0-8	Slg1p	Saccharomyces cerevisiae S288C	16-20
33771930-0	2021	Methanol sensor Wsc1 and MAP kinase suppress degradation of methanol-induced peroxisomes in methylotrophic yeast.	Methanol	60-68	Slg1p	Saccharomyces cerevisiae S288C	16-20
33825397-2	2021	METHODS: Maximal non-toxic dose (MNTD) of methanol extract of P. ginseng root culture on BV2 microglia cells was first determined via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, followed by treatment and LPS stimulation of cells, and the measurement of NO using Griess assay and TNF-alpha, IL-6, and IL-10 using ELISA assay.	Methanol	42-50	tumor necrosis factor	Mus musculus	303-312
33825397-2	2021	METHODS: Maximal non-toxic dose (MNTD) of methanol extract of P. ginseng root culture on BV2 microglia cells was first determined via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, followed by treatment and LPS stimulation of cells, and the measurement of NO using Griess assay and TNF-alpha, IL-6, and IL-10 using ELISA assay.	Methanol	42-50	interleukin 10	Mus musculus	324-329
23260349-3	2013	Structure-activity optimization of lead 5 with cyclohexyl carbinols resulted in compound 12, which showed excellent in vitro potency and selectivity against COX-2, and reasonable pharmacokinetic properties.	Methanol	58-67	cytochrome c oxidase subunit II	Cavia porcellus	157-162
33773249-5	2021	However, excessive methanol (>5 mM) combined with BDE-47 had strong stress on microbial cells, including significant (p < 0.05) increase of reactive oxygen species level, superoxide dismutase activity, catalase activity and malondialdehyde content, even causing 20.65% cell apoptosis and 11.27% death.	Methanol	19-27	catalase	Homo sapiens	202-210
29274566-1	2018	Formaldehyde dehydrogenase (FaldDH) is used as a catalyst to reduce formate to formaldehyde in a cascade reaction to convert CO2 to methanol.	Methanol	132-140	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	0-26
29274566-1	2018	Formaldehyde dehydrogenase (FaldDH) is used as a catalyst to reduce formate to formaldehyde in a cascade reaction to convert CO2 to methanol.	Methanol	132-140	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	28-34
25724770-5	2015	DLPC was dispersed in a chloroform/methanol mixture that was spread on a free PLA2 solution surface.	Methanol	35-43	phospholipase A2 group IIA	Homo sapiens	78-82
8070342-7	1994	Both TA3 and TA4 glucuronides were hydrolyzed by treatment for 30 min at 37 C with 0.1 M NaOH and showed transesterification to the methyl esters by treatment with methanol, suggesting that they represent ester glucuronides with the carboxyl group.	Methanol	164-172	trace amine associated receptor 9	Homo sapiens	5-8
9714758-6	1998	Using beta-lactamase as a reporter, we show that the FLD1 promoter (PFLD1) is strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source).	Methanol	123-131	seipin	Saccharomyces cerevisiae S288C	53-57
8070342-7	1994	Both TA3 and TA4 glucuronides were hydrolyzed by treatment for 30 min at 37 C with 0.1 M NaOH and showed transesterification to the methyl esters by treatment with methanol, suggesting that they represent ester glucuronides with the carboxyl group.	Methanol	164-172	trace amine associated receptor 6	Homo sapiens	13-16
8070342-5	1994	Both TA3 and TA4 glucuronides were stable during treatment with dilute base or methanol, suggesting that they represent ether glucuronides with the phenolic hydroxyl group.	Methanol	79-87	trace amine associated receptor 9	Homo sapiens	5-8
34775036-13	2022	In addition, methanol extract of Zanthoxylum armatum DC caused ATM-mediated DNA damage, further phosphorylated Chk2, inhibited cell cycle related proteins, and arrested the G1/S cycle.	Methanol	13-21	ATM serine/threonine kinase	Rattus norvegicus	63-66
8070342-5	1994	Both TA3 and TA4 glucuronides were stable during treatment with dilute base or methanol, suggesting that they represent ether glucuronides with the phenolic hydroxyl group.	Methanol	79-87	trace amine associated receptor 6	Homo sapiens	13-16
34775036-13	2022	In addition, methanol extract of Zanthoxylum armatum DC caused ATM-mediated DNA damage, further phosphorylated Chk2, inhibited cell cycle related proteins, and arrested the G1/S cycle.	Methanol	13-21	checkpoint kinase 2	Rattus norvegicus	111-115
34311304-8	2022	The Fe-N/CB catalyst also displays better stability and methanol resistance than Pt/C.	Methanol	56-64	FECB	Homo sapiens	4-11
34715746-6	2022	This study was undertaken to determine the optimal fixation method, methanol or formalin, for the detection of claudin 1 and E-cadherin by immunofluorescence in five different human breast cancer cell lines.	Methanol	68-76	claudin 1	Homo sapiens	111-120
34715746-6	2022	This study was undertaken to determine the optimal fixation method, methanol or formalin, for the detection of claudin 1 and E-cadherin by immunofluorescence in five different human breast cancer cell lines.	Methanol	68-76	cadherin 1	Homo sapiens	125-135
34714058-0	2022	Ascendancy of Nitrogen Heterocycles in the Computationally Designed Mn(I)PNN Pincer Catalysts on the Hydrogenation of Carbon Dioxide to Methanol.	Methanol	136-144	pinin, desmosome associated protein	Homo sapiens	73-76
34714058-3	2022	This article provides comprehensive density functional theoretic investigations of six new Mn(I)PNN complexes, which are designed to perform CO2 to methanol conversion under milder reaction conditions.	Methanol	148-156	pinin, desmosome associated protein	Homo sapiens	96-99
34714058-5	2022	All these computationally modeled Mn(I)PNN complexes demonstrate the promising catalytic activity to get methanol through cascade catalytic cycles at 298.15 K. The metal-ligand cooperative (MLC) as well as noncooperative (NC) pathways are investigated for each catalytic cycle.	Methanol	105-113	pinin, desmosome associated protein	Homo sapiens	39-42
34375870-4	2021	This paper provides a comprehensive review, including: (1) The impact of pollutants such as NOX, SOX, CO2 and PM emitted by ships on the environment and human health; (2) New regulations about ship exhaust emissions; (3) Application of clean energy such as LNG, biodiesel, methanol, hydrogen and ammonia on ships; (4) After-treatment technology of ship exhaust gas such as SCR and EGR.	Methanol	273-281	inositol polyphosphate-5-phosphatase D	Homo sapiens	348-352
34832958-0	2021	Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on alpha-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol.	Methanol	156-164	STAM binding protein	Mus musculus	86-95
34190667-0	2021	Anti-inflammatory effect of Barringtonia angusta methanol extract is mediated by targeting of Src in the NF-kappaB signalling pathway.	Methanol	49-57	Rous sarcoma oncogene	Mus musculus	94-97
34940295-0	2021	Development of Methanol Sensor Based on Sol-Gel Drop-Coating Co3O4 CdO ZnO Nanoparticles Modified Gold-Coated micro-Chip by Electro-Oxidation Process.	Methanol	15-23	cell adhesion associated, oncogene regulated	Homo sapiens	67-70
34762803-0	2021	Near-Surface Gas-Phase Methoxymethanol Is Generated by Methanol Oxidation over Pd-Based Catalysts.	Methanol	55-63	PAXIP1 associated glutamate rich protein 1	Homo sapiens	13-16
34762803-2	2021	We examined catalytic oxidative conversion of methanol near atmospheric pressure using operando small-aperture molecular beam time-of-flight mass spectrometry, interrogating the gas phase 500 mum above Pd-based catalyst surfaces.	Methanol	46-54	PAXIP1 associated glutamate rich protein 1	Homo sapiens	178-181
34816846-1	2021	The reaction of MnCl2 4H2O, H8L (2,2"-bis-p-tBu-calix(4)arene) and NEt3 in a dmf/MeOH solvent mixture results in the formation of a mixed valent decametallic cluster of formula (MnII6MnIII4(L)2(mu3-OH)4(mu-OH)4(MeOH)4(dmf)4(MeCN)2) MeCN (3).	Methanol	81-85	tetraspanin 2	Homo sapiens	67-71
34961160-9	2021	The methanol extract showed the AGI activity (IC50 = 2.71 +- 0.11 mug/mL), insulin-sensitizing activity (at a concentration of 5 microg/mL), and potent antioxidant activities (IC50 = 10.85 mug/mL and 72.53 mg AAE/g for DPPH and FRAP activity, respectively).	Methanol	4-12	preproinsulin	Danio rerio	75-82
34961160-9	2021	The methanol extract showed the AGI activity (IC50 = 2.71 +- 0.11 mug/mL), insulin-sensitizing activity (at a concentration of 5 microg/mL), and potent antioxidant activities (IC50 = 10.85 mug/mL and 72.53 mg AAE/g for DPPH and FRAP activity, respectively).	Methanol	4-12	mechanistic target of rapamycin kinase	Mus musculus	228-232
34741432-0	2021	In Situ Replacement Synthesis of Co@NCNT Encapsulated CoPt3 @Co2 P Heterojunction Boosting Methanol Oxidation and Hydrogen Evolution.	Methanol	91-99	complement C2	Homo sapiens	61-64
34708839-5	2021	After optimization, the ELISA showed a half-maximum signal inhibition concentration (IC50) of 0.39 ng mL-1 in phosphate-buffered saline (pH 7, 20% MeOH) and a limit of detection (LOD) of 0.02 ng mL-1, which was more sensitive than the parent Nb-based ELISAs with IC50 and LOD values of 1.4 ng mL-1 and 0.1 ng mL-1, respectively.	Methanol	147-151	L1 cell adhesion molecule	Mus musculus	102-106
34130174-5	2021	Benefiting from the 3D hydrogel structure, rich defects and optimized chemical properties, GH N-C-900 prepared by NH3 pyrolysis at 900  C exhibits an excellent electrocatalytic performance toward ORR, with the onset potential of 0.947 +- 0.013 V versus RHE, half-wave potential of 0.830 +- 0.010 V versus RHE, electron transfer number of 3.61-3.99, along as methanol tolerance and superior long-term stability.	Methanol	358-366	growth hormone 1	Homo sapiens	91-95
34698322-10	2021	The primary products of HAO6 and HAN7 reactions, including (9MG + HO6)+/(9MG + HN7)+ and  OH, react further to either form (8OH-9MG + HO6) + and (8OH-9MG + HN7) +via C8-hydroxylation or form radical cations of 6-enol-guanine (6-enol-G +) and 7H-guanine (7HG +) via SN2-type methanol elimination.	Methanol	274-282	MT-RNR2 like 7 (pseudogene)	Homo sapiens	79-82
34693946-1	2021	Well-defined and air-stable PN3-pincer manganese(II) complexes were synthesized and used for the hydrogenation of aldehydes into alcohols under mild conditions using MeOH as a solvent.	Methanol	166-170	sodium voltage-gated channel alpha subunit 10	Homo sapiens	28-31
34731167-5	2021	The apoferritin hydrogel did not decompose in the presence of 1 M HCl, 2-mercaptoethanol, or methanol but was dissolved in the presence of 1 M NaOH, by heating at 80 C, or by treatment with trypsin or 6 M guanidine hydrochloride.	Methanol	93-101	ferritin heavy chain 1	Homo sapiens	4-15
34698322-10	2021	The primary products of HAO6 and HAN7 reactions, including (9MG + HO6)+/(9MG + HN7)+ and  OH, react further to either form (8OH-9MG + HO6) + and (8OH-9MG + HN7) +via C8-hydroxylation or form radical cations of 6-enol-guanine (6-enol-G +) and 7H-guanine (7HG +) via SN2-type methanol elimination.	Methanol	274-282	MT-RNR2 like 7 (pseudogene)	Homo sapiens	156-159
34714942-2	2022	A ~200-fold decrease in fluorescence quantum yield of m-NMe2 -LpHBDI in alcohols (e.g., MeOH, EtOH, and 2-PrOH) supports this GFP-derived compound as a fluorescence turn-on water sensor, with large fluorescence intensity differences between H2 O and ROH emissions in various H2 O/ROH binary mixtures.	Methanol	88-92	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	56-60
34778610-0	2021	Gas-Phase Catalytic Dehydration of Glycerol with Methanol to Methyl Glyceryl Ethers over Phosphotungstic Acid Supported on Alumina.	Methanol	49-57	gastrin	Homo sapiens	0-3
34643376-4	2021	Employing a nickelII pincer complex (((N2N)Ni-Cl)) in combination with carbon-13 labeled CO, alkyl iodide, sodium methoxide, photocatalyst, and blue LED light, it was possible to generate the corresponding isotopically labeled aliphatic carboxylates in good yields.	Methanol	107-123	notch 2 N-terminal like A	Homo sapiens	39-42
34834697-1	2021	Methanol Extract by Inhibiting Src Activity in the NF-kappaB Pathway.	Methanol	0-8	nuclear factor kappa B subunit 1	Homo sapiens	51-60
34186080-5	2021	Surprisingly, the methanol extract possesses hepato and nephroprotective activity against CCl4 and cisplatin-induced cytotoxicity on HepG2 and HEK 293 cell lines, respectively.	Methanol	18-26	C-C motif chemokine ligand 4	Homo sapiens	90-94
34091342-5	2021	During the O3/PMS process, ribavirin was dehydrogenated at the hydroxyl groups first, then lost the amide or the methanol group.	Methanol	113-121	proline rich protein BstNI subfamily 1	Homo sapiens	14-17
34684679-6	2021	MeOH extract, EtOAc fraction, and 1-3 suppressed NO formation in LPS-stimulated RAW 264.7 cells and decreased iNOS and COX-2 expression.	Methanol	0-4	nitric oxide synthase 2, inducible	Mus musculus	110-114
34684679-6	2021	MeOH extract, EtOAc fraction, and 1-3 suppressed NO formation in LPS-stimulated RAW 264.7 cells and decreased iNOS and COX-2 expression.	Methanol	0-4	cytochrome c oxidase II, mitochondrial	Mus musculus	119-124
34477762-4	2021	A Co-bpe MOF was synthesized by hydrothermal reaction between cobalt nitrate and 1,2-bis(4-pyridyl)ethylene (bpe) in methanol and tested against colorimetric sensing of halides.	Methanol	117-125	lysine acetyltransferase 8	Homo sapiens	9-12
34391081-0	2021	Methanol extract of Sedum oryzifolium and its constituent, trehalose, impede the invasiveness of oral squamous cell carcinoma cell lines via downregulation of Slug.	Methanol	0-8	snail family transcriptional repressor 2	Homo sapiens	159-163
34582889-1	2021	The zinc finger transcription factor Mxr1p regulates the transcription of genes involved in methanol, acetate and amino acid metabolism of the industrial yeast Pichia pastoris (a.k.a.	Methanol	92-100	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	37-42
34582889-8	2021	While the N-terminal 400 amino acids of Mxr1p are sufficient for the activation of target genes essential for ethanol metabolism, the region between amino acids 401 and 1155 was also required for the regulation of genes essential for methanol metabolism.	Methanol	234-242	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	40-45
34582889-9	2021	Finally, we identified several novel genes whose expression is differentially regulated by Mxr1p during methanol metabolism by DNA microarray.	Methanol	104-112	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	91-96
34391081-7	2021	RESULTS: Among the methanol extracts of 18 various wild plants from South Korea, MESO exhibited the highest anticancer functionality in OSCC cells by downregulating Slug expression.	Methanol	19-27	snail family transcriptional repressor 2	Homo sapiens	165-169
34588860-5	2021	The results revealed the crude methanol (PHM) fraction of P. hydaspidis shown dose and time dependent cell-proliferative inhibition response.	Methanol	31-39	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	41-44
34588860-11	2021	This suggests the methanol fraction of P. hydaspidis (PHM) to have anticancer compounds, potentially useful for treating liver and breast cancer.	Methanol	18-26	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	54-57
34494839-0	2021	Exploration of Gas-Liquid Interfaces for Liquid Water and Methanol Using Extreme Ultraviolet Laser Photoemission Spectroscopy.	Methanol	58-66	gastrin	Homo sapiens	15-18
34379429-4	2021	The method is benchmarked by computing the ground-state room-temperature relative stabilities between (i) the cis and trans isomers of prototypal animal and microbial rhodopsins and (ii) the analogue isomers of a rhodopsin-like light-driven molecular switch in methanol.	Methanol	261-269	rhodopsin	Homo sapiens	213-222
34478307-5	2021	In the process, SP1, SP2, and SP3 can be isomerized from a closed-ring form (hydrophobicity) to an open-ring form (hydrophilicity) in different degrees, interacting differently with methanol solvent molecules.	Methanol	182-190	Sp2 transcription factor	Homo sapiens	21-24
34478307-5	2021	In the process, SP1, SP2, and SP3 can be isomerized from a closed-ring form (hydrophobicity) to an open-ring form (hydrophilicity) in different degrees, interacting differently with methanol solvent molecules.	Methanol	182-190	Sp3 transcription factor	Homo sapiens	30-33
34310047-0	2021	Low Temperature Methanol-Water Reforming over the Alcohol Dehydrogenase and Immobilized Ruthenium Complex.	Methanol	16-24	aldo-keto reductase family 1 member A1	Homo sapiens	50-71
34310047-6	2021	We employ the alcohol dehydrogenase (ADH) and coenzyme I (NAD + ) for methanol catalytic dehydrogenation at low temperature, which could generate formaldehyde and reductive coenzyme I (NADH).	Methanol	70-78	aldo-keto reductase family 1 member A1	Homo sapiens	14-35
34310047-6	2021	We employ the alcohol dehydrogenase (ADH) and coenzyme I (NAD + ) for methanol catalytic dehydrogenation at low temperature, which could generate formaldehyde and reductive coenzyme I (NADH).	Methanol	70-78	aldo-keto reductase family 1 member A1	Homo sapiens	37-40
34465086-5	2021	A continuous variation method (Job plot) illustrated a 1.5:1 ligand/thorium (L/Th) ratio in a methanol phase, indicating that L1/L2 and Th(IV) could form mixed 1:1 and 2:1 L/Th extracted complexes.	Methanol	94-102	L1 cell adhesion molecule	Homo sapiens	126-131
34577485-7	2021	Handheld Raman equipped with a 1064 nm excitation laser gave the best results for determining ethanol (SEP = 1.2%; RPre = 0.95) and methanol (SEP = 1.8 mg/100 mL; RPre = 0.93).	Methanol	132-140	septin 1	Homo sapiens	142-149
33691844-3	2021	As a result, higher electrochemical surface area (ECSA) and methanol oxidation reactions were obtained, and the electrochemical properties of Pt-c(NH2-MIL-101)@NCNT are better than pristine Pt-c(NH2-MIL-101).	Methanol	60-68	ret proto-oncogene	Homo sapiens	142-146
34503410-16	2021	MeOH fractions notably reduced MMP-2 secretion levels of in the culture supernatants from HT-1080 cells.	Methanol	0-4	matrix metallopeptidase 2	Homo sapiens	31-36
34475400-3	2021	We find that Pt1/RuO2 has good electrocatalytic activity towards methanol oxidation in an alkaline media with a mass activity that is 15.3-times higher than that of commercial Pt/C (6766 vs. 441 mA mg-1Pt).	Methanol	65-73	zinc finger protein 77	Homo sapiens	13-16
34475400-7	2021	Ab initio simulations and experiments reveal that the presence of Pt-O3f (3-fold coordinatively bonded O)-Rucus (coordinatively unsaturated Ru) bonds with the undercoordinated bridging O in Pt1/RuO2 favors the electrochemical dehydrogenation of methanol with lower energy barriers and onset potential than those encountered for Pt-C and Pt-Ru.	Methanol	245-253	zinc finger protein 77	Homo sapiens	190-193
34466108-4	2021	The current study is intended to investigate the in vivo antipyretic activity of the methanol extract of C. digyna leaves (MECD) and its carbon-tetrachloride (CTCD) and butanol fraction (BTCD).	Methanol	85-93	Kin17 DNA and RNA binding protein	Homo sapiens	187-191
34466072-2	2021	In the present investigation, we evaluated the anticancer effects of Parrotiopsis jacquemontiana methanol fraction (PJM) on STAT3 inhibition in HCCLM3 and MDA-MB 231 cells.	Methanol	97-105	signal transducer and activator of transcription 3	Homo sapiens	124-129
34573361-0	2021	Beta vulgaris rubra L. (Beetroot) Peel Methanol Extract Reduces Oxidative Stress and Stimulates Cell Proliferation via Increasing VEGF Expression in H2O2 Induced Oxidative Stressed Human Umbilical Vein Endothelial Cells.	Methanol	39-47	vascular endothelial growth factor A	Homo sapiens	130-134
34404870-6	2021	Using nuclear magnetic resonance (NMR) metabolomics, 8 metabolites (fatty acid, propionate, isopropanol, lactate, acetone, valine, methanol and formate) were identified to be significantly dysregulated in ACO subjects when compared to both, asthma and COPD.	Methanol	131-139	kallikrein related peptidase 15	Homo sapiens	205-208
34573021-8	2021	We also observed the reduction of PC3 viability occurring following exposure to methanol and methanol/water extracts.	Methanol	80-88	chromobox 8	Homo sapiens	34-37
34573021-8	2021	We also observed the reduction of PC3 viability occurring following exposure to methanol and methanol/water extracts.	Methanol	93-101	chromobox 8	Homo sapiens	34-37
34573021-11	2021	Intriguingly, the gene expression of COX-2 and TNFalpha was reduced in PC3 cells after exposure to methanol and methanol/water extracts.	Methanol	99-107	chromobox 8	Homo sapiens	71-74
34573021-11	2021	Intriguingly, the gene expression of COX-2 and TNFalpha was reduced in PC3 cells after exposure to methanol and methanol/water extracts.	Methanol	112-120	chromobox 8	Homo sapiens	71-74
34189811-11	2021	It is demonstrated that Al and Sn can be incorporated into the FDP zeolite framework to produce active and selective methanol-to-hydrocarbon and glucose isomerization catalysts, respectively.	Methanol	117-125	otoraplin	Homo sapiens	63-66
34578509-1	2021	Recently, alkaline direct methanol fuel cells have made great progress with the development of alkaline electrocatalysis, and a wide variety of catalysts have been explored for methanol oxidation reaction (MOR)and oxygen reduction reaction (ORR).	Methanol	26-34	opioid receptor mu 1	Homo sapiens	206-209
34578509-1	2021	Recently, alkaline direct methanol fuel cells have made great progress with the development of alkaline electrocatalysis, and a wide variety of catalysts have been explored for methanol oxidation reaction (MOR)and oxygen reduction reaction (ORR).	Methanol	177-185	opioid receptor mu 1	Homo sapiens	206-209
34380313-2	2021	We recently reported a Co(III)-N2O2 complex with a 2,2"-bipyridine-based ligand backbone which showed alternative selectivity: H2O was observed as the primary reduction product from O2 (71 +- 5%) with decamethylferrocene as a chemical reductant and acetic acid as a proton donor in methanol solution.	Methanol	282-290	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	23-30
34443161-2	2021	The study found that the paper can realize the reversible control of surface wettability through the exchange between the anions PF6- and Cl- adsorbed on the surface of PMETAC, and further investigation of the effect of different solvents on the ion exchange properties found that water was the poor solvent for ion exchange, while the mixtures of methanol, acetone, and methanol & water were the good solvent.	Methanol	348-356	sperm associated antigen 17	Homo sapiens	129-132
34443161-2	2021	The study found that the paper can realize the reversible control of surface wettability through the exchange between the anions PF6- and Cl- adsorbed on the surface of PMETAC, and further investigation of the effect of different solvents on the ion exchange properties found that water was the poor solvent for ion exchange, while the mixtures of methanol, acetone, and methanol & water were the good solvent.	Methanol	371-379	sperm associated antigen 17	Homo sapiens	129-132
34436390-0	2021	Development of Methanol Permselective FAU-Type Zeolite Membranes and Their Permeation and Separation Performances.	Methanol	15-23	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	38-41
34436390-3	2021	As a result, the FAU-type zeolite membrane prepared using a solution with a composition of 10 SiO2:1 Al2O3:17 Na2O:1000 H2O showed the highest permeation flux of 86,600 mumol m-2 s-1 and a separation factor of 6020 for a 10 wt% methanol/methyl hexanoate mixture at 353 K. The membrane showed a molecular sieving effect, reducing the single permeation flux of alcohol with molecular size for single-component alcohols.	Methanol	228-236	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	17-20
34451703-9	2021	The DPPH free radical and alpha-glucosidase inhibitions was highest in the leaf ethyl acetate fraction, with IC50 of 6.39 and 4.93 microg/mL, respectively, while the leaf methanol crude extract and butanol fraction exhibited the highest FRAP with 82.95 and 82.17 mmol Fe (II)/g extract.	Methanol	171-179	sucrase-isomaltase	Homo sapiens	26-43
34380347-7	2021	The methanol leaves extract showed good anticancer activity against U87 (IC50 = 21.40 microg/mL) and PC-3 cells (IC50 = 10.26 microg/mL).	Methanol	4-12	small nucleolar RNA, C/D box 87	Homo sapiens	68-71
34324070-7	2021	The minimum inhibitory concentration of methanol extract of Ramalina sinensis were 0.9-1.8 mg mL- 1.	Methanol	40-48	L1 cell adhesion molecule	Mus musculus	94-99
34343036-3	2021	The methanol leaf extract of G. thunbergia inhibited Plasmodium falciparum at 50 microg/mL (> 80% inhibition) and was not cytotoxic against HeLa cells.	Methanol	4-12	thrombopoietin	Mus musculus	88-90
34443392-3	2021	The 80% methanol extract of Machilus thunbergii bark significantly inhibited the signal transducer and activator of transcription 5 (STAT5) phosphorylation in human mast cell (HMC)-1 cells.	Methanol	8-16	signal transducer and activator of transcription 5A	Homo sapiens	133-138
34309354-0	2021	Bifunctional Pd@RhPd Core-Shell Nanodendrites for Methanol Electrolysis.	Methanol	50-58	nephrocystin 3	Homo sapiens	16-20
34324070-11	2021	The IC50 values estimated for methanol extracts of Peltigera praetextata, Evernia prunastri, Ramalina sinensis and Ramalina farinacea species in HeLa cell line were within 1.8-2.8 mg mL- 1 and considered as non-cytotoxic.	Methanol	30-38	L1 cell adhesion molecule	Mus musculus	183-188
34386633-2	2021	Then, they were used in CO and CO2 hydrogenation to produce methanol under atmospheric pressure at 250  C. The high Cu loading CZA catalyst (CZA-H) resulted in the enhancement of structural features and textural properties (e.g., BET surface area and the crystallite size of copper species).	Methanol	60-68	delta/notch like EGF repeat containing	Homo sapiens	230-233
34183691-1	2021	Present work comprehensively investigated the electrochemical response of Nickel-2 Aminoterephthalic acid Metal-Organic Framework (NiNH2BDC) and its reduced graphitic carbon (rGO) based hybrids for methanol (CH3OH) oxidation reaction (MOR) in an alkaline environment.	Methanol	198-206	opioid receptor mu 1	Homo sapiens	235-238
34247144-15	2021	Both treatments work by blocking the metabolism of methanol by liver alcohol dehydrogenase (ADH).	Methanol	51-59	aldo-keto reductase family 1 member A1	Homo sapiens	92-95
34196847-5	2021	However, the complete dehydrogenation product of methanol, CO, is easier to dissociate from PtCu2 clusters than from Pt3 and Pt2Cu clusters.	Methanol	49-57	zinc finger protein 135	Homo sapiens	117-120
34361559-5	2021	Quantum chemical calculations of the interaction energy between beta-CD and BA as well as the structure of the (BA beta-CD) complex and the energy of beta-CD and BA interaction in vacuum and in the medium of water, methanol and dimethylsulfoxide solvents are carried out.	Methanol	215-223	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	150-157
34236188-2	2021	Compounds 1, 4 MeOH, and its desolvated form 4 exhibited an invariant high-spin state in the whole temperature range, while 2 and 3 underwent gradual, nonhysteretic, and incomplete spin crossover (SCO) with transition temperatures (TC) of 153 and 220 K, respectively.	Methanol	15-19	spindlin 1	Homo sapiens	75-79
34236188-3	2021	Interestingly, the SCO-active compounds 2 and 3 showed light-induced excited spin-state trapping (LIESST) effects at 10 K, and light-induced reversible ON/OFF switching behaviors were realized by alternately using 880 and 1064 nm light, while the thermally inert compound 4 MeOH unexpectedly showed a reverse-LIESST effect.	Methanol	274-278	spindlin 1	Homo sapiens	77-81
34300636-2	2021	In this study, we have developed a biochemical gas sensor (bio-sniffer) for MeOH in the gas phase using fluorometry and a cascade reaction with two enzymes, alcohol oxidase (AOD) and formaldehyde dehydrogenase (FALDH).	Methanol	76-80	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	183-209
34300636-2	2021	In this study, we have developed a biochemical gas sensor (bio-sniffer) for MeOH in the gas phase using fluorometry and a cascade reaction with two enzymes, alcohol oxidase (AOD) and formaldehyde dehydrogenase (FALDH).	Methanol	76-80	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	211-216
34300636-3	2021	In the cascade reaction, oxidation of MeOH was initially catalyzed by AOD to produce formaldehyde, and then this formaldehyde was successively oxidized via FALDH catalysis together with reduction of oxidized form of beta-nicotinamide adenine dinucleotide (NAD+).	Methanol	38-42	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	156-161
34300636-5	2021	In the development of the MeOH bio-sniffer, three conditions were optimized: selecting a suitable FALDH for better discrimination of MeOH from ethanol in the cascade reaction; buffer pH that maximizes the cascade reaction; and materials and methods to prevent leaking of NAD+ solution from an AOD-FALDH membrane.	Methanol	26-30	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	98-103
34300636-5	2021	In the development of the MeOH bio-sniffer, three conditions were optimized: selecting a suitable FALDH for better discrimination of MeOH from ethanol in the cascade reaction; buffer pH that maximizes the cascade reaction; and materials and methods to prevent leaking of NAD+ solution from an AOD-FALDH membrane.	Methanol	26-30	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	297-302
34300636-5	2021	In the development of the MeOH bio-sniffer, three conditions were optimized: selecting a suitable FALDH for better discrimination of MeOH from ethanol in the cascade reaction; buffer pH that maximizes the cascade reaction; and materials and methods to prevent leaking of NAD+ solution from an AOD-FALDH membrane.	Methanol	133-137	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	98-103
34266277-8	2021	It is found that in water and methanol, the most abundant conformers of ML are structurally modified relative to the gas phase, where the major form is ML1, in which the syn conformation of the -OH moiety is stabilized by a OH O=C intramolecular hydrogen bond (HB).	Methanol	30-38	interleukin 17F	Homo sapiens	152-155
34266277-8	2021	It is found that in water and methanol, the most abundant conformers of ML are structurally modified relative to the gas phase, where the major form is ML1, in which the syn conformation of the -OH moiety is stabilized by a OH O=C intramolecular hydrogen bond (HB).	Methanol	30-38	synemin	Homo sapiens	170-173
34266277-11	2021	The relative abundance of ML1 is shown to decrease from ~96% in gas to ~51% in water and ~92% in methanol.	Methanol	97-105	interleukin 17F	Homo sapiens	26-29
34170102-3	2021	We developed a simple method to prepare a nickel foam (NF)-based monolith electrode with a NiO nanosheet array structure as an efficient electrocatalyst toward the oxidation of methanol to produce formate.	Methanol	177-185	neurofascin	Homo sapiens	55-57
34170102-5	2021	In alkaline electrolytes containing methanol, the as-prepared NiO/NF catalysts exhibited a lower methanol oxidation reaction (MOR) potential of +1.53 V vs RHE at 100 mA cm-2 compared to that of inert NF samples.	Methanol	36-44	neurofascin	Homo sapiens	66-68
34170102-5	2021	In alkaline electrolytes containing methanol, the as-prepared NiO/NF catalysts exhibited a lower methanol oxidation reaction (MOR) potential of +1.53 V vs RHE at 100 mA cm-2 compared to that of inert NF samples.	Methanol	97-105	neurofascin	Homo sapiens	66-68
34170102-8	2021	NiO/NF retained close to 100% of its initial activity after 20,000 s of methanol oxidation tests at high current densities above 200 mA cm-2.	Methanol	72-80	neurofascin	Homo sapiens	4-6
34170102-9	2021	Because of the simple synthesis method and the enhanced catalytic performance and stability of NiO/NF, this allows methanol to be used as an OER masking agent for the energy-efficient generation of value-added products such as formic acid and hydrogen.	Methanol	115-123	neurofascin	Homo sapiens	99-101
34226600-3	2021	The following factors have been investigated on their effects on FAME yield: baffles, reaction volume, total reactant flow rate, methanol-oil molar ratio, catalyst concentration and reaction temperature.	Methanol	129-137	benign adult familial myoclonic epilepsy 1	Homo sapiens	65-69
34323033-2	2021	Methods: The formulation of insulin-loaded water-in-oil-in-water solid lipid nanoparticles (INS-SNPs) was prepared by using a methanol-chloroform mixed solvent.	Methanol	126-134	insulin	Homo sapiens	28-35
34258287-7	2021	Concerning the inhibitory effect on pancreatic alpha-amylase, it was found that in the in vitro study, the best IC50 registered were those of EtOH (0.25 mg/ml), MeOH (0.10 mg/ml), aqueous (0.031 mg/ml), and n-hexane fraction (0.76 mg/ml), while in the in vivo study an important inhibition of alpha-amylase in normal and diabetic rats was observed.	Methanol	161-165	amylase 2a3	Rattus norvegicus	36-60
34183691-1	2021	Present work comprehensively investigated the electrochemical response of Nickel-2 Aminoterephthalic acid Metal-Organic Framework (NiNH2BDC) and its reduced graphitic carbon (rGO) based hybrids for methanol (CH3OH) oxidation reaction (MOR) in an alkaline environment.	Methanol	208-213	opioid receptor mu 1	Homo sapiens	235-238
34203819-5	2021	Differential scanning calorimetric analysis of a methanol suspension of Sil-VPG15 indicated that the G moieties formed a highly ordered structure below the phase transition temperature even on the silica surface, and the ordered G moieties exhibited a gel-to-liquid crystalline phase transition.	Methanol	49-57	STIL centriolar assembly protein	Homo sapiens	72-75
34141419-4	2021	Discussion: Methanol is usually rapidly absorbed after ingestion and metabolized by alcohol dehydrogenase (ADH), then distributed to the body water to reach a volume distribution approximately equal to 0.77 L/kg.	Methanol	12-20	aldo-keto reductase family 1 member A1	Homo sapiens	84-105
34141419-4	2021	Discussion: Methanol is usually rapidly absorbed after ingestion and metabolized by alcohol dehydrogenase (ADH), then distributed to the body water to reach a volume distribution approximately equal to 0.77 L/kg.	Methanol	12-20	aldo-keto reductase family 1 member A1	Homo sapiens	107-110
34070837-6	2021	In HEK-293 cells, the MeOH extract possessed cellular antioxidant effects by attenuating hydrogen peroxide (H2O2)-induced ROS production and increasing catalase, glutathione peroxidase-1 (GPx-1), and glutathione reductase (GRe).	Methanol	22-26	catalase	Homo sapiens	152-160
34059939-0	2021	Impact of glycerol feeding profiles on STEAP1 biosynthesis by Komagataella pastoris using a methanol-inducible promoter.	Methanol	92-100	STEAP family member 1	Homo sapiens	39-45
34059939-4	2021	Based on the results presented, this work proposes the application, for the first time, of a fed-batch profile to improve STEAP1 biosynthesis in mini-bioreactor Komagataella pastoris X-33 Mut+ methanol-induced cultures, by evaluating three glycerol feeding profiles-constant, exponential, and gradient-during the pre-induction phase.	Methanol	193-201	STEAP family member 1	Homo sapiens	122-128
34059939-7	2021	The supplementation of culture medium with 6 % (v/v) DMSO and 1 M proline onto a gradient glycerol/constant methanol feeding promoted increased biosynthesis levels of STEAP1 and minimized aggregation events.	Methanol	108-116	STEAP family member 1	Homo sapiens	167-173
34070837-6	2021	In HEK-293 cells, the MeOH extract possessed cellular antioxidant effects by attenuating hydrogen peroxide (H2O2)-induced ROS production and increasing catalase, glutathione peroxidase-1 (GPx-1), and glutathione reductase (GRe).	Methanol	22-26	glutathione peroxidase 1	Homo sapiens	162-186
34070837-6	2021	In HEK-293 cells, the MeOH extract possessed cellular antioxidant effects by attenuating hydrogen peroxide (H2O2)-induced ROS production and increasing catalase, glutathione peroxidase-1 (GPx-1), and glutathione reductase (GRe).	Methanol	22-26	glutathione peroxidase 1	Homo sapiens	188-193
34070837-6	2021	In HEK-293 cells, the MeOH extract possessed cellular antioxidant effects by attenuating hydrogen peroxide (H2O2)-induced ROS production and increasing catalase, glutathione peroxidase-1 (GPx-1), and glutathione reductase (GRe).	Methanol	22-26	glutathione-disulfide reductase	Homo sapiens	200-221
34334521-11	2021	The melittin neutralization efficiency of NPs depended on the purification process; i.e., it decreased by acetone precipitation and increased by dialysis in methanol and centrifugation compared with that of control NPs.	Methanol	157-165	melittin	Apis mellifera	4-12
34065429-0	2021	TAK1/AP-1-Targeted Anti-Inflammatory Effects of Barringtonia augusta Methanol Extract.	Methanol	69-77	mitogen-activated protein kinase kinase kinase 7	Mus musculus	0-4
34065429-0	2021	TAK1/AP-1-Targeted Anti-Inflammatory Effects of Barringtonia augusta Methanol Extract.	Methanol	69-77	jun proto-oncogene	Mus musculus	5-9
34065429-2	2021	Here, we examine how the methanol extract of Barringtonia augusta (B. augusta) can suppress the activator protein 1 (AP-1) signaling pathway and study the activities of Ba-ME in the lipopolysaccharide (LPS)-treated RAW264.7 macrophage cell line and an LPS-induced peritonitis mouse model.	Methanol	25-33	jun proto-oncogene	Mus musculus	96-115
34914300-7	2021	The expression of vimentin mRNA in the testis tissue was significantly reduced in the VC model control in comparison with that in the blank control group (0.18 +- 0.03 vs 1.00 +- 0.02), but dramatically up-regulated after treated with low-dose MOH (0.68 +- 0.07) and high-dose MOH (0.92 +- 0.08) (F = 432.901, P< 0.01).	Methanol	244-247	vimentin	Rattus norvegicus	18-26
34914300-7	2021	The expression of vimentin mRNA in the testis tissue was significantly reduced in the VC model control in comparison with that in the blank control group (0.18 +- 0.03 vs 1.00 +- 0.02), but dramatically up-regulated after treated with low-dose MOH (0.68 +- 0.07) and high-dose MOH (0.92 +- 0.08) (F = 432.901, P< 0.01).	Methanol	277-280	vimentin	Rattus norvegicus	18-26
34914300-9	2021	The level of testicular miR-210, however, was significantly increased in the VC model controls compared with the blank controls (1.39 +- 0.12 vs 1.00 +- 0.06), but decreased in both the low-dose MOH (1.17 +- 0.08) and high-dose MOH groups (1.09 +- 0.08) (F = 36.136, P< 0.01).	Methanol	195-198	microRNA 210	Rattus norvegicus	24-31
34914300-9	2021	The level of testicular miR-210, however, was significantly increased in the VC model controls compared with the blank controls (1.39 +- 0.12 vs 1.00 +- 0.06), but decreased in both the low-dose MOH (1.17 +- 0.08) and high-dose MOH groups (1.09 +- 0.08) (F = 36.136, P< 0.01).	Methanol	228-231	microRNA 210	Rattus norvegicus	24-31
34104310-8	2021	In particular, the methanol extract was the most effective in protecting neuron-like SH-SY5Y cells against H2O2-induced oxidative stress by upregulating endogenous antioxidant enzymes such as thioredoxin reductase, heme oxygenase 1, NADPH quinone oxidoreductase, and glutathione reductase.	Methanol	19-27	heme oxygenase 1	Homo sapiens	215-231
34104310-8	2021	In particular, the methanol extract was the most effective in protecting neuron-like SH-SY5Y cells against H2O2-induced oxidative stress by upregulating endogenous antioxidant enzymes such as thioredoxin reductase, heme oxygenase 1, NADPH quinone oxidoreductase, and glutathione reductase.	Methanol	19-27	glutathione-disulfide reductase	Homo sapiens	267-288
34915831-12	2021	P. nitida and A. indica methanol extracts showed potent inhibition of P-gp activity (IC50: 3.8 and 5.4 microg/mL), respectively, while V. amygdalina and M. oleifera methanol extracts showed moderate P-gp inhibition (IC50: 12.1 and 37.2 microg/mL, respectively).	Methanol	24-32	ATP binding cassette subfamily B member 1	Homo sapiens	70-74
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	40-44	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	56-62
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	40-44	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	135-141
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	102-106	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	135-141
34275786-1	2021	This study was carried out to isolate the secondary metabolites and to evaluate the antibacterial, antifungal, antioxidant, phytotoxic, anti-leishmanial and alpha-glucosidase activities of dichloromethane and methanol extracts of whole plant of Astragalus creticus.	Methanol	209-217	AT695_RS09985	Staphylococcus aureus	157-174
34275786-5	2021	The methanol extract exhibited better activity against Staphylococcus aureus (58.75%) while dichloromethane extract was found to be very active against Bacillus subtilis (56.30%).The methanol extract demonstrated highly significant phytotoxic (92.68% at 1000mug/ml) and antioxidant (64.55+-0.43%) potential while both extracts identified best inhibition of alpha-glucosidase enzyme.	Methanol	4-12	AT695_RS09985	Staphylococcus aureus	357-374
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	102-106	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	150-156
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	102-106	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	168-173
34842392-6	2021	In BeWo cells, all concentrations of PI-MeOH induced <i>CYP2E1</i>, 100 and 500 mug Ml<sup>1</sup> PI-MeOH and PI-EtOH up-regulated <i>CYP1A2</i>, <i>CYP3A4 </i>and <i>ABCG2 </i>and 500 mug mL<sup>1</sup> PI-EtOH induced <i>ABCG2</i> expression.	Methanol	102-106	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	224-229
34842392-9	2021	<i>ABCC1</i> expression was induced by all treatments while <i>ABCG2</i> and <i>SLC22A11 </i>were induced only by 500 mug mL<sup>1</sup> PI-MeOH and PI-EtOH.	Methanol	140-144	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	63-68
34842392-9	2021	<i>ABCC1</i> expression was induced by all treatments while <i>ABCG2</i> and <i>SLC22A11 </i>were induced only by 500 mug mL<sup>1</sup> PI-MeOH and PI-EtOH.	Methanol	140-144	solute carrier family 22 member 11	Homo sapiens	80-88
35602425-6	2022	The in vitro alpha-amylase (4-10%), alpha-glucosidase (5-17%) and DPP-IV (3-26%) inhibition (IC50) of methanol extracts were higher than the aqueous extracts.	Methanol	102-110	Agl1	Hordeum vulgare	36-53
35358622-7	2022	Molecular docking and dynamics were used for in silico testing of the inhibitory activity of chlorogenic (CA) and rosmarinic (RA) acids, as the dominant compounds in the tested methanol extracts against COX-1 and COX-2 enzymes.	Methanol	177-185	cytochrome c oxidase I, mitochondrial	Rattus norvegicus	203-208
35550750-3	2022	The proposed multichiral beta-CD@Ca-sacc/MeOH/GCE can be used for recognition of tryptophan and penicillamine enantiomers simultaneously with wide linear range, low detection limits value, high repeatability and stability within the available electrochemical window.	Methanol	41-45	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	25-32
35535493-2	2022	Using a genetic screen in haploid human cells, we discovered that the enantiospecific cytotoxicity of numerous terminal alkynylcarbinols, including the highly cytotoxic dialkynylcarbinols, involves a bioactivation by HSD17B11, a short-chain dehydrogenase/reductase (SDR) known to oxidize the C-17 carbinol center of androstan-3-alpha,17-beta-diol to the corresponding ketone.	Methanol	297-305	hydroxysteroid 17-beta dehydrogenase 11	Homo sapiens	217-225
35556178-6	2022	Similar dimorphic shift was also displayed by a recombinant methanol slow utilizing (Muts) strain (SMD-GCSF Muts) producing human granulocyte colony-stimulating factor in response to change in the initial inoculum level.	Methanol	60-68	colony stimulating factor 3	Homo sapiens	130-167
35403181-7	2022	A methanol extract of precipitates exhibited a potent anti-proliferative effect on MCF-7 cells (IC50 = 0.032 mug muL-1) via inhibiting tubulin polymerization.	Methanol	2-10	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	113-118
35178660-3	2022	Dexamethasone-induced MuRF1 expression was significantly suppressed by methanol-soluble part of boiling water extract of PA in a concentration-dependent manner with its IC50 value of 1.5 mg/ml.	Methanol	71-79	tripartite motif-containing 63	Mus musculus	22-27
35614111-3	2022	Here, we perform anodic electrochemical oxidation of Ni-metalloids (NiPx, NiSx, and NiSex) to in-situ construct different oxyanion-coordinated amorphous nickel oxyhydroxides (NiOOH-TOx), among which NiOOH-POx shows optimal local coordination environment and boosts electrocatalytic activity of Ni sites towards selective oxidation of methanol to formate.	Methanol	334-342	thymocyte selection associated high mobility group box	Homo sapiens	181-184
34990765-11	2022	RESULTS: The results showed that the NXT extract exhibited great activity against thrombin and FXa, especially extracted by 75% methanol (v/v).	Methanol	128-136	coagulation factor X	Homo sapiens	95-98
35419694-5	2022	Using a previously described AlphaScreen-based protein interaction assay, we show here that the DCM:MeOH extract of G. perpensa readily disrupts RBD (USA-WA1/2020)-ACE2 interactions with a half-maximal inhibition concentration (IC50) of < 0.001 microg/mL, compared to an IC50 of 0.025 microg/mL for the control neutralising antibody REGN10987.	Methanol	100-104	angiotensin converting enzyme 2	Homo sapiens	164-168
35506238-7	2022	Similarly, in the root tip, the activity of cyclin B1:1 was detected on exposure to (-)-borneol and methanol, but not on exposure to (+)-borneol, indicating that (+)-borneol inhibits the meristematic activity in the root.	Methanol	100-108	CYCLIN B1;1	Arabidopsis thaliana	44-55
35470958-3	2022	A novel fluorescence probe ZL-1 with a large Stokes shift (in methanol it reached to 153 nm and in glycerol it reached to 125 nm) and excellent sensitivity toward viscosity was developed.	Methanol	62-70	small Cajal body-specific RNA 28	Homo sapiens	27-31
35470958-4	2022	The sharp enhancement of the emission intensity for the probe ZL-1 from low viscous methanol to high viscous glycerol indicated the probe ZL-1 could be respond to the viscosity variations.	Methanol	84-92	small Cajal body-specific RNA 28	Homo sapiens	62-66
35470958-4	2022	The sharp enhancement of the emission intensity for the probe ZL-1 from low viscous methanol to high viscous glycerol indicated the probe ZL-1 could be respond to the viscosity variations.	Methanol	84-92	small Cajal body-specific RNA 28	Homo sapiens	138-142
34990765-11	2022	RESULTS: The results showed that the NXT extract exhibited great activity against thrombin and FXa, especially extracted by 75% methanol (v/v).	Methanol	128-136	coagulation factor II, thrombin	Homo sapiens	82-90
35445232-3	2022	However, our in situ Raman results show that the onset transition pressure can be as low as 9.7 GPa when using the methanol-ethanol-water (MEW) mixture as the pressure-transmitting medium (PTM), indicated by an additional GD Raman peak caused by the sp3 bonding between adjacent graphite layers.	Methanol	115-123	Sp3 transcription factor	Homo sapiens	250-253
35452068-3	2022	The synthesized material (DUT-52-(NH2)2-1) was solvent exchanged with methanol (MeOH) and activated at 100  C overnight.	Methanol	70-78	deoxyuridine triphosphatase	Homo sapiens	26-29
35452068-3	2022	The synthesized material (DUT-52-(NH2)2-1) was solvent exchanged with methanol (MeOH) and activated at 100  C overnight.	Methanol	80-84	deoxyuridine triphosphatase	Homo sapiens	26-29
35199936-2	2022	Poly(4-vinylphenylboronic acid/styrene-co-ethylene dimethacrylate/divinylbenzene) monolith was fabricated and employed as the extraction phase for efficient entrapment of Se(IV) complexed with o-phenylenediamine, followed by elution with a methanol/formic acid (99/1.0, v/v) mixture and quantification by high-performance liquid chromatography with diode array detector.	Methanol	240-248	squalene epoxidase	Homo sapiens	171-177
35467722-5	2022	Methanol extracts of purple yam exhibited the highest COMT inhibitory activity of the tested samples.	Methanol	0-8	catechol-O-methyltransferase	Homo sapiens	54-58
35500389-12	2022	(v) Cell3 is the only CSP that provides marked complementary enantioselectivity to that of Cell2, almost orthogonal in MeOH/H2O mobile phases.	Methanol	119-123	carboxyl ester lipase pseudogene	Homo sapiens	4-9
35500389-12	2022	(v) Cell3 is the only CSP that provides marked complementary enantioselectivity to that of Cell2, almost orthogonal in MeOH/H2O mobile phases.	Methanol	119-123	carboxyl ester lipase pseudogene	Homo sapiens	91-96
35517506-2	2022	Two cell wall integrity and stress response component (WSC) family proteins (Wsc1 and Wsc3) sense the extracellular methanol concentration and transmit the methanol signal to Rom2.	Methanol	116-124	Slg1p	Saccharomyces cerevisiae S288C	77-81
35517506-2	2022	Two cell wall integrity and stress response component (WSC) family proteins (Wsc1 and Wsc3) sense the extracellular methanol concentration and transmit the methanol signal to Rom2.	Methanol	116-124	Wsc3p	Saccharomyces cerevisiae S288C	86-90
35517506-2	2022	Two cell wall integrity and stress response component (WSC) family proteins (Wsc1 and Wsc3) sense the extracellular methanol concentration and transmit the methanol signal to Rom2.	Methanol	156-164	Slg1p	Saccharomyces cerevisiae S288C	77-81
35517506-2	2022	Two cell wall integrity and stress response component (WSC) family proteins (Wsc1 and Wsc3) sense the extracellular methanol concentration and transmit the methanol signal to Rom2.	Methanol	156-164	Wsc3p	Saccharomyces cerevisiae S288C	86-90
35517506-2	2022	Two cell wall integrity and stress response component (WSC) family proteins (Wsc1 and Wsc3) sense the extracellular methanol concentration and transmit the methanol signal to Rom2.	Methanol	156-164	Rho family guanine nucleotide exchange factor ROM2	Saccharomyces cerevisiae S288C	175-179
35517506-9	2022	In the presence of methanol, Wsc1 and Wsc3 repress pexophagy by transmitting the methanol signal via the MAPK cascade to the transcription factor Rlm1, which induces phosphatases involved in dephosphorylation of Atg30.	Methanol	19-27	Slg1p	Saccharomyces cerevisiae S288C	29-33
35517506-9	2022	In the presence of methanol, Wsc1 and Wsc3 repress pexophagy by transmitting the methanol signal via the MAPK cascade to the transcription factor Rlm1, which induces phosphatases involved in dephosphorylation of Atg30.	Methanol	19-27	Rlm1p	Saccharomyces cerevisiae S288C	146-150
35517506-9	2022	In the presence of methanol, Wsc1 and Wsc3 repress pexophagy by transmitting the methanol signal via the MAPK cascade to the transcription factor Rlm1, which induces phosphatases involved in dephosphorylation of Atg30.	Methanol	81-89	Slg1p	Saccharomyces cerevisiae S288C	29-33
35517506-9	2022	In the presence of methanol, Wsc1 and Wsc3 repress pexophagy by transmitting the methanol signal via the MAPK cascade to the transcription factor Rlm1, which induces phosphatases involved in dephosphorylation of Atg30.	Methanol	81-89	Wsc3p	Saccharomyces cerevisiae S288C	38-42
35517506-9	2022	In the presence of methanol, Wsc1 and Wsc3 repress pexophagy by transmitting the methanol signal via the MAPK cascade to the transcription factor Rlm1, which induces phosphatases involved in dephosphorylation of Atg30.	Methanol	81-89	Rlm1p	Saccharomyces cerevisiae S288C	146-150
35199573-7	2022	Furthermore, methanol-fixed images of PTEN were consistent with GFP-tagged live-cell images.	Methanol	13-21	phosphatase and tensin homolog	Homo sapiens	38-42
35384306-7	2022	In addition, it was demonstrated that competitive experiments could be performed with our miniaturized system to confirm the existence and the binding pocket of a ligand to AChE contained in a methanol plant extract.	Methanol	193-201	acetylcholinesterase (Cartwright blood group)	Homo sapiens	173-177
35199573-8	2022	Two immunofluorescence methods (the PFA-fixed/pre-boiled EDTA treatment and methanol fixation) are applicable to investigations of the intracellular localization of PTEN without a GFP tag in cultured cells.	Methanol	76-84	phosphatase and tensin homolog	Homo sapiens	165-169
35224851-0	2022	Defect-Rich, Highly Porous PtAg Nanoflowers with Superior Anti-Poisoning Ability for Efficient Methanol Oxidation Reaction.	Methanol	95-103	rhomboid domain containing 3	Homo sapiens	27-31
35424967-2	2022	Under the optimal esterification conditions (i.e., at 65  C for 2 h using a methanol/OA molar ratio of 10 : 1 with a catalyst dosage of 4 wt%), the FAME yield was 97.05 +- 0.28% when a solid acid catalyst prepared by loading 6 g of p-Toluenesulfonic acid (p-TSA) on 2 g of activated biochar (p-TSA3/ABC) was used.	Methanol	76-84	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	299-302
35217709-3	2022	Although recovery was similar with UAE and MAE, 3 min MAE with 80% ethanol and 80% methanol produced the highest yields of total phenolic content (TPC), total flavonoid content (TFC) and phenolic acids.	Methanol	83-91	solute carrier family 6 member 1	Homo sapiens	54-57
35453375-10	2022	L. maackianus MeOH extract induced heme oxygenase-1 expression and increased the translocation of nuclear factor E2-related factor 2 in the nucleus, thus exhibiting antioxidant and anti-inflammatory effects.	Methanol	14-18	heme oxygenase 1a	Danio rerio	35-51
35453375-12	2022	MeOH L. maackianus extract showed antioxidant and anti-neuroinflammatory effects by increasing the expression of heme oxygenase-1, establishing its therapeutic potential for neuroinflammatory diseases.	Methanol	0-4	heme oxygenase 1a	Danio rerio	113-129
35209821-4	2022	METHOD: This study was designed to explore the in vitro anticancer activity of the three fractions of lac dye, i.e., chloroform (C), methanol (M) and water (W) fractions and isolation of constituents from bioactive fraction.	Methanol	133-141	lactase	Homo sapiens	102-105
35159819-9	2022	Furthermore, it was found that Pt-TiO2 provides the highest methanol yield of 17.85 micromol/gcat/h, and CO as a minor product.	Methanol	60-68	glycine C-acetyltransferase	Homo sapiens	93-97
35044248-17	2022	MeOH and EtOAc extracts, as well as the bioactive compounds reversed the toxic effect of dexamethasone by increasing the cell viability, SIRT3 protein expression but reducing the ROS, autophagy and apoptosis.	Methanol	0-4	sirtuin 3	Homo sapiens	137-142
35164229-3	2022	Ethyl acetate (ARE) and methanol (ARM) extracts significantly decreased mRNA levels of IL-6, TNF-alpha, MCP-1, COX-2, and iNOS.	Methanol	24-32	interleukin 6	Mus musculus	87-91
35284727-4	2022	In methanol, friction and wear are determined by the hydrogen bonding structure, where friction coefficients relate on saturation effects of sp3-CH, and the wear properties depend on the "collapse effect" that the more the sp3-CH3 and sp3-CH2, the easier the wear out of bulk a-C:H films.	Methanol	3-11	Sp3 transcription factor	Homo sapiens	141-144
35284727-4	2022	In methanol, friction and wear are determined by the hydrogen bonding structure, where friction coefficients relate on saturation effects of sp3-CH, and the wear properties depend on the "collapse effect" that the more the sp3-CH3 and sp3-CH2, the easier the wear out of bulk a-C:H films.	Methanol	3-11	Sp3 transcription factor	Homo sapiens	223-226
35284727-4	2022	In methanol, friction and wear are determined by the hydrogen bonding structure, where friction coefficients relate on saturation effects of sp3-CH, and the wear properties depend on the "collapse effect" that the more the sp3-CH3 and sp3-CH2, the easier the wear out of bulk a-C:H films.	Methanol	3-11	Sp3 transcription factor	Homo sapiens	235-238
35209742-1	2022	OBJECTIVE: To compare the initial clinical course and data on 90-day mortality in adults with methanol (MET) or ethylene glycol (EG) poisoning treated with dialysis.	Methanol	94-102	SAFB like transcription modulator	Homo sapiens	104-107
34985213-13	2022	Similarly, compounds such as remifentanil bearing a methyl formate substituent at the piperidine para-position also produced numerous fragment ions, which were more prone to the rH pathway to lose methyl formate or methanol neutral molecules and furnish fragment ions with m/z 317 or 345.	Methanol	215-223	Rh blood group, D antigen	Rattus norvegicus	178-180
35065580-0	2022	New insights into methanol and formic acid electro-oxidation on Pt: Simultaneous DEMS and ATR-SEIRAS study under well-defined flow conditions and simulations of CO spectra.	Methanol	18-26	ATR serine/threonine kinase	Homo sapiens	90-93
35065580-1	2022	Methanol and formic acid electro-oxidation on Pt has been studied under well-defined flow conditions by a spectroscopic platform that combines differential electrochemical mass spectrometry (DEMS) and attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy.	Methanol	0-8	ATR serine/threonine kinase	Homo sapiens	257-260
35065580-2	2022	The volatile soluble products from methanol and formic acid oxidation on Pt have been detected by DEMS, while adsorbed intermediates have been identified with ATR-FTIR spectroscopy.	Methanol	35-43	ATR serine/threonine kinase	Homo sapiens	159-162
35425232-3	2022	In the methanol electrooxidation reaction, the particles showed high catalytic activity and strong resistance to the poisoning carbonaceous species in comparison with those of commercial Pt/C and the as-prepared Pt/C catalysts.	Methanol	7-15	ret proto-oncogene	Homo sapiens	187-191
35425232-3	2022	In the methanol electrooxidation reaction, the particles showed high catalytic activity and strong resistance to the poisoning carbonaceous species in comparison with those of commercial Pt/C and the as-prepared Pt/C catalysts.	Methanol	7-15	ret proto-oncogene	Homo sapiens	212-216
31474160-7	2022	The cells were pretreated with four different concentrations (10, 50, 100, and 200 microg/ml) of methanol:water (1:1), chloroform and n-hexane extracts of P. pyrrhoblepharus following MPP+ treatment for 12 or 24 h. The changes in cell viability were determined using the MTT assay.	Methanol	97-105	M-phase phosphoprotein 6	Homo sapiens	184-187
34918244-8	2022	112-608aa ORF2 VLPs are secreted into the culture medium in a methanol inducible manner.	Methanol	62-70	OFD1, centriole and centriolar satellite protein	Mus musculus	10-14
35291606-8	2022	Results: The maximum expression level of rCAP18 (17.5 kDa) was seen 90 h after induction of alcohol oxidase I (AOX1) promoter with methanol.	Methanol	131-139	aldehyde oxidase 1	Oryctolagus cuniculus	111-115
2684960-6	1989	A region of the amino acid sequence of Pol I (peptide I) consisting of residues 728-777 has been synthesized and found to contain significant secondary structure by CD both in water and 50% methanol/water.	Methanol	190-198	DNA polymerase iota	Homo sapiens	39-44
2624319-3	1989	Evaluation of the assay procedure was carried out with 1-naphthalene-methanol as a model substrate for purified rat hepatic aryl sulfotransferase IV.	Methanol	69-77	sulfotransferase family 1A member 1	Rattus norvegicus	124-148
2677012-2	1989	HDGF was purified from bovine myocardium using a procedure that involves denaturation of undesired proteins with methanol and chloroform.	Methanol	113-121	heparin binding growth factor	Bos taurus	0-4
2575456-7	1989	On the other hand, double labelling with [3H]-thymidine and with the cyclin/PCNA antibody revealed that in methanol-fixed tissues the cyclin/PCNA labelling index did not differ by more than 6% from the [3H]-thymidine index.	Methanol	107-115	proliferating cell nuclear antigen	Homo sapiens	69-75
2775851-2	1989	CD spectra indicated a disordered secondary structure in water and a beta-sheet conformation in aqueous organic solvents, such as methanol, dioxane, and trifluoroethanol (in trifluoroethanol a transient form evolving toward beta-sheet conformation was seen just after dissolution).	Methanol	130-138	amyloid beta precursor protein	Homo sapiens	67-73
2575456-7	1989	On the other hand, double labelling with [3H]-thymidine and with the cyclin/PCNA antibody revealed that in methanol-fixed tissues the cyclin/PCNA labelling index did not differ by more than 6% from the [3H]-thymidine index.	Methanol	107-115	proliferating cell nuclear antigen	Homo sapiens	76-80
2733692-0	1989	Studies on the mechanism of methanol poisoning: purification and comparison of rat and human liver 10-formyltetrahydrofolate dehydrogenase.	Methanol	28-36	aldehyde dehydrogenase 1 family member L1	Homo sapiens	99-138
2770757-3	1989	Stimulation of H2O2 production by BHA in S9 or microsome incubation mixtures was demonstrated using the catalase-mediated production of formaldehyde from methanol.	Methanol	154-162	catalase	Cricetulus griseus	104-112
2550226-11	1989	A fluorescent intermediate was also observed in the catalytic cycle of MDH with methanol as a substrate.	Methanol	80-88	malate dehydrogenase 2	Homo sapiens	71-74
2549948-5	1989	The product formed from methylated protein by PME was confirmed as methanol by h.p.l.c.	Methanol	67-75	cystatin B	Homo sapiens	46-49
2504624-2	1989	Synthetic TRH was incubated in rat serum and extracted in 90% methanol for measurement of tripeptide by RIA.	Methanol	62-70	thyrotropin releasing hormone	Homo sapiens	10-13
2752013-3	1989	TNF productivity of 0.108 g L-1 h-1 was obtained in the continuous mode on glycerol- and methanol-mixed feed at 25 g dry cell weight/L cell density.	Methanol	89-97	tumor necrosis factor	Homo sapiens	0-3
2494285-8	1989	The biological activity which reduced the responsiveness of the pituitary gland towards stimulation by LHRH was eliminated after the use of protein-denaturating techniques such as increased temperature or addition of methanol.	Methanol	217-225	gonadotropin releasing hormone 1	Rattus norvegicus	103-107
2730873-1	1989	Structures have been determined for a potent analogue of vasoactive intestinal peptide (VIP), Ac-[Lys12, Lys14, Nle17, Val26, Thr28]VIP (VIP"), in methanol/water solutions.	Methanol	147-155	vasoactive intestinal peptide	Homo sapiens	88-91
2730873-1	1989	Structures have been determined for a potent analogue of vasoactive intestinal peptide (VIP), Ac-[Lys12, Lys14, Nle17, Val26, Thr28]VIP (VIP"), in methanol/water solutions.	Methanol	147-155	vasoactive intestinal peptide	Homo sapiens	132-135
2730873-1	1989	Structures have been determined for a potent analogue of vasoactive intestinal peptide (VIP), Ac-[Lys12, Lys14, Nle17, Val26, Thr28]VIP (VIP"), in methanol/water solutions.	Methanol	147-155	vasoactive intestinal peptide	Homo sapiens	132-135
2730873-2	1989	In CD studies, both VIP and VIP" were helical in methanol/water, with the percentage of alpha-helix increasing with percentage methanol.	Methanol	49-57	vasoactive intestinal peptide	Homo sapiens	20-23
2730873-2	1989	In CD studies, both VIP and VIP" were helical in methanol/water, with the percentage of alpha-helix increasing with percentage methanol.	Methanol	49-57	vasoactive intestinal peptide	Homo sapiens	28-31
2730873-2	1989	In CD studies, both VIP and VIP" were helical in methanol/water, with the percentage of alpha-helix increasing with percentage methanol.	Methanol	127-135	vasoactive intestinal peptide	Homo sapiens	20-23
2730873-2	1989	In CD studies, both VIP and VIP" were helical in methanol/water, with the percentage of alpha-helix increasing with percentage methanol.	Methanol	127-135	vasoactive intestinal peptide	Homo sapiens	28-31
2730873-4	1989	Complete 1H NMR assignments were made for VIP" in 25% methanol at pH 4 and 6 and in 50% methanol at pH 6, using two-dimensional COSY, NOESY, and relay-COSY experiments.	Methanol	54-62	vasoactive intestinal peptide	Homo sapiens	42-45
2730873-6	1989	Complete sets of NOEs were obtained for VIP" in 25% methanol, pH 4, and in 50% methanol, pH 6.	Methanol	52-60	vasoactive intestinal peptide	Homo sapiens	40-43
2730873-9	1989	In 25% methanol, VIP" has two helical segments at residues 9-17 and 23-28.	Methanol	7-15	vasoactive intestinal peptide	Homo sapiens	17-21
2730873-14	1989	In the lowest energy structure in 50% methanol, the side chains of Asp3, Phe6, Thr7, and Tyr10 are clustered together--these residues are conserved throughout the family of peptide hormones homologous to VIP.	Methanol	38-46	vasoactive intestinal peptide	Homo sapiens	204-207
2464071-2	1988	Rapid and efficient separation of labelled PLP from other proteins and lipids was effected by extraction into chloroform/methanol/0.1 N HCl (10/10/1) and chromatography on Sephadex LH-60 in the same solvent.	Methanol	121-129	proteolipid protein 1	Homo sapiens	43-46
2708495-1	1989	Twenty-four PTH-amino acids are rapidly and efficiently separated on a packed cyanopropyl Zorbax column by gradient elution of supercritical CO2 and tetramethylammonium hydroxide-modified methanol.	Methanol	188-196	parathyroid hormone	Homo sapiens	12-15
2680403-4	1989	Studies of rates of oxidation of butanol, a specific substrate for alcohol dehydrogenase, and methanol, a substrate for catalase, indicate that peroxidation via catalase supported by H2O2 formed by the peroxisomal beta-oxidation of fatty acids is the predominant pathway of alcohol oxidation in the fasted state.	Methanol	94-102	catalase	Homo sapiens	120-128
2680403-4	1989	Studies of rates of oxidation of butanol, a specific substrate for alcohol dehydrogenase, and methanol, a substrate for catalase, indicate that peroxidation via catalase supported by H2O2 formed by the peroxisomal beta-oxidation of fatty acids is the predominant pathway of alcohol oxidation in the fasted state.	Methanol	94-102	catalase	Homo sapiens	161-169
3169021-10	1988	The effects of ethanol, methanol, tetrahydrofuran, acetonitrile, acetone and dimethylsulfoxide on microsomal epoxide hydrolase depended on the substrate tested, whereas both cytosolic enzymes were not at all, or only slightly, affected by these solvents.	Methanol	24-32	epoxide hydrolase 1	Rattus norvegicus	98-126
2643580-1	1989	Resequencing estA3, an allele of the methanol-soluble heat-stable enterotoxin of Escherichia coli showed that the proline triplet 19 is in fact an alanine codon; thus, estA alleles 3 and 4 were shown to be identical.	Methanol	37-45	heat stable enterotoxin A3	Escherichia coli	13-18
2903166-1	1988	UV irradiation of quiescent human fibroblasts immediately triggers the appearance of the nuclear protein cyclin/proliferating cell nuclear antigen (PCNA) as detected by indirect immunofluorescent staining after methanol fixation.	Methanol	211-219	proliferating cell nuclear antigen	Homo sapiens	105-146
2903166-1	1988	UV irradiation of quiescent human fibroblasts immediately triggers the appearance of the nuclear protein cyclin/proliferating cell nuclear antigen (PCNA) as detected by indirect immunofluorescent staining after methanol fixation.	Methanol	211-219	proliferating cell nuclear antigen	Homo sapiens	148-152
3242946-3	1988	The pK values of dPGP in aqueous dispersions or in methanol/water (1:1, v/v) were determined by potentiometric titration and compared with those of 2,3-diphytanyl-sn-glycerol-1-phosphoryl-3"-sn-glycerol-1"-phosphat e (PGP).	Methanol	51-59	phosphoglycolate phosphatase	Homo sapiens	18-21
3169246-1	1988	Methanol and butanol were employed as selective substrates for catalase-H2O2 and alcohol dehydrogenase (ADH), respectively, in the perfused rat liver.	Methanol	0-8	catalase	Rattus norvegicus	63-71
3416882-11	1988	H2O2 generation was determined from the time necessary for steady-state level of catalase-H2O2, measured spectrophotometrically (660-640 nm) through a lobe of the liver, to return to basal values after the addition of a known quantity of methanol, which is not metabolized by ADH in the rat.	Methanol	238-246	catalase	Rattus norvegicus	81-89
3056073-1	1988	4-Methylpyrazole (4-MP), an inhibitor of alcohol dehydrogenase, is a possible future drug for the treatment of methanol and ethylene glycol intoxications and the severe ethanol-disulfiram reaction.	Methanol	111-119	aldo-keto reductase family 1 member A1	Homo sapiens	41-62
20539381-1	1988	Quarterwave antireflective coatings of CaF(2) and MgF(2) have been prepared on fused silica and calcium fluoride substrates from colloidal suspensions of the relevant fluorides in methanol.	Methanol	180-188	signal transducer and activator of transcription 5A	Homo sapiens	50-53
2833567-4	1988	The intensity of labelling by anti-VP7 antibodies was markedly increased by treatment of the virus with methanol.	Methanol	104-112	VP7	Bluetongue virus	35-38
16347719-8	1988	When wild-type H. polymorpha was grown on mixtures of glucose and methanol, the CCP level was independent of the rate of methanol utilization, whereas the level of catalase increased with increasing amounts of methanol in the substrate feed.	Methanol	66-74	cytochrome-c peroxidase	Saccharomyces cerevisiae S288C	80-83
3167030-4	1988	The results show that 50% v/v methanol lowers the values of kcat from 2- to 12-fold compared to the reactions in the absence of methanol for all of the metallo-LAP, but that the values of KM are essentially unaffected.	Methanol	30-38	LAP	Homo sapiens	160-163
3167030-4	1988	The results show that 50% v/v methanol lowers the values of kcat from 2- to 12-fold compared to the reactions in the absence of methanol for all of the metallo-LAP, but that the values of KM are essentially unaffected.	Methanol	128-136	LAP	Homo sapiens	160-163
2453217-2	1988	As previously observed for substance P and physalaemin, two tachykinins acting via the NK-1 receptor, [Cys3,6,Tyr8]substance P presents an alpha-helical structure of the 4----8 sequence in methanol.	Methanol	189-197	tachykinin precursor 1	Homo sapiens	27-38
2453217-2	1988	As previously observed for substance P and physalaemin, two tachykinins acting via the NK-1 receptor, [Cys3,6,Tyr8]substance P presents an alpha-helical structure of the 4----8 sequence in methanol.	Methanol	189-197	tachykinin receptor 1	Homo sapiens	87-100
2453217-2	1988	As previously observed for substance P and physalaemin, two tachykinins acting via the NK-1 receptor, [Cys3,6,Tyr8]substance P presents an alpha-helical structure of the 4----8 sequence in methanol.	Methanol	189-197	tachykinin precursor 1	Homo sapiens	115-126
2892857-2	1988	With this assay, the quantity of Thy-1 antigen on R615B2 cells was detected separately in the cytoplasm and on the cell surface by the use of appropriate fixatives such as chilled ethanol and methanol + 0.3% H2O2.	Methanol	192-200	Thy-1 cell surface antigen	Rattus norvegicus	33-46
3127944-4	1988	Eighteen hours after alcohol administration (1/2 LD50 dose, po), CS2 microsomal MFO metabolism was significantly enhanced, in order of descending potency, by isopropanol, methanol, and ethanol pretreatments, but not by isobutanol pretreatment.	Methanol	171-179	calsyntenin 2	Rattus norvegicus	65-68
3127944-10	1988	Unlike other alcohol pretreatments, methanol decreased the total 14C expired during the 3-hr period after CS2 dosing and caused a significant (twofold) increase in plasma glutamic-pyruvic transaminase, measured 24 hr after CS2 exposure (625 mg/kg).	Methanol	36-44	calsyntenin 2	Rattus norvegicus	106-109
3127944-10	1988	Unlike other alcohol pretreatments, methanol decreased the total 14C expired during the 3-hr period after CS2 dosing and caused a significant (twofold) increase in plasma glutamic-pyruvic transaminase, measured 24 hr after CS2 exposure (625 mg/kg).	Methanol	36-44	calsyntenin 2	Rattus norvegicus	223-226
2447244-10	1988	Similarly, the effect of PLA2 was also inhibited by methanol (1 mM), a scavenger of the hydroxyl radical, and by catalase.	Methanol	52-60	phospholipase A2 group IB	Rattus norvegicus	25-29
3355670-2	1988	The involvement of catalase was confirmed by its blocking by aminotriazole (AT) or methanol but not by pyrazole or butanol.	Methanol	83-91	catalase	Rattus norvegicus	19-27
3178785-1	1988	Methanol, ethanol and isopropanol were tested for the ability to change effects of chlorinated hydrocarbons on the alanine aminotransferase (ALAT = GPT; EC 2.6.1.2.)	Methanol	0-8	glutamic--pyruvic transaminase	Rattus norvegicus	148-151
11540080-1	1988	We report observations, for the first time, of the 2(0) - 1(0)A+ and E, 2(-1) - 1(-1) E, and 1(0) - 0(0)A+ lines of methanol (CH3OH) in three dark cold clouds, TMC1, L134N, and B335.	Methanol	116-124	transmembrane channel like 1	Homo sapiens	160-164
3436953-3	1987	Slightly changed spectra were observed for SEP1-15 and SEP1-20 in the buffer containing neutral liposomes and in MeOH, respectively.	Methanol	113-117	septin 1	Homo sapiens	43-47
2964865-1	1987	The bovine mitochondrial gene products ND2 and ND4, components of NADH dehydrogenase, have been purified from a chloroform/methanol extract of mitochondrial membranes, and the human mitochondrial gene products ND2 and cytochrome b have been obtained by similar procedures.	Methanol	123-131	NADH dehydrogenase subunit 2	Bos taurus	39-42
2964865-1	1987	The bovine mitochondrial gene products ND2 and ND4, components of NADH dehydrogenase, have been purified from a chloroform/methanol extract of mitochondrial membranes, and the human mitochondrial gene products ND2 and cytochrome b have been obtained by similar procedures.	Methanol	123-131	NADH dehydrogenase subunit 4	Bos taurus	47-50
3431551-10	1987	In addition, MEF partitioned to the aqueous phase during methanol-chloroform extraction procedures.	Methanol	57-65	E74 like ETS transcription factor 4	Homo sapiens	13-16
3680315-7	1987	Casting from acetone, which is an excellent solvent for PLA, resulted in hard blocks exhibiting lower degrees of crystallinity, while methanol had a similar effect on PEO soft segments.	Methanol	134-142	twinkle mtDNA helicase	Homo sapiens	167-170
3380525-1	1988	Two chemoattractants for retinal pigment epithelial (RPE) cells, fibronectin (FN) and platelet-derived growth factor (PDGF) were found to enhance protein carboxymethylation mediated by S-adenosyl-L-methionine in RPE cells measured by [3H]methanol hydrolyzed from TCA precipitable protein methyl esters labelled with [3H]methionine.	Methanol	238-246	fibronectin 1	Homo sapiens	65-76
3380525-1	1988	Two chemoattractants for retinal pigment epithelial (RPE) cells, fibronectin (FN) and platelet-derived growth factor (PDGF) were found to enhance protein carboxymethylation mediated by S-adenosyl-L-methionine in RPE cells measured by [3H]methanol hydrolyzed from TCA precipitable protein methyl esters labelled with [3H]methionine.	Methanol	238-246	fibronectin 1	Homo sapiens	78-80
3322284-3	1987	DCX was purified by preparative thin layer chromatography from chloroform: methanol = 4:1 extracts of whole bacteria, and is chromatographically homogeneous.	Methanol	75-83	doublecortin	Homo sapiens	0-3
3319289-1	1987	This method for the specific determination of methanol in serum is based on the following two reactions: (formula; see text) Alcohol oxidase is not specific: it converts all lower alcohols to their corresponding aldehydes; however, formaldehyde dehydrogenase is specific and thus the transformation of NAD+ to NADH (which is used to monitor the reaction) proceeds only if methanol is originally present in the sample.	Methanol	46-54	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	232-258
3319289-1	1987	This method for the specific determination of methanol in serum is based on the following two reactions: (formula; see text) Alcohol oxidase is not specific: it converts all lower alcohols to their corresponding aldehydes; however, formaldehyde dehydrogenase is specific and thus the transformation of NAD+ to NADH (which is used to monitor the reaction) proceeds only if methanol is originally present in the sample.	Methanol	372-380	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	232-258
2890619-4	1987	Exogenous sources of soluble TGase were transferred to the extracellular matrix of an untreated or methanol fixed cell.	Methanol	99-107	transglutaminase 1	Homo sapiens	29-34
3123349-6	1987	The elution profile of methanol-extracted rat adrenal gland TRH was identical to that for synthetic TRH.	Methanol	23-31	thyrotropin releasing hormone	Rattus norvegicus	60-63
3436953-3	1987	Slightly changed spectra were observed for SEP1-15 and SEP1-20 in the buffer containing neutral liposomes and in MeOH, respectively.	Methanol	113-117	septin 1	Homo sapiens	55-62
3623715-10	1987	The second-generation antibodies show a spectrum of reactivity on tissues similar to HMFG-2 and one reacts at least as strongly as HMFG-2 with methanol-acetone-fixed sections of breast cancers.	Methanol	143-151	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	131-135
2957172-2	1987	All four solvent systems are potentially suitable as cryosolvents for plasmin catalysis at subzero temperatures although the solubility of plasmin is limited in the methanol and dimethyl sulfoxide systems.	Methanol	165-173	plasminogen	Homo sapiens	139-146
3476960-6	1987	The membrane FBP, following delipidation with chloroform/methanol, contained 7.1 mol of fatty acid per mol of protein, of which 4.7 mol was amide-linked and 2.4 mol was ester-linked.	Methanol	57-65	folate receptor beta	Homo sapiens	13-16
2822029-1	1987	Stimulation of human or rabbit platelets with thrombin in the presence of fibrinogen caused a large decrease, compared with unstimulated controls, in the amount of phosphatidylinositol 4,5-bisphosphate (PIP2) that could be extracted with acidified chloroform/methanol (60% at 60 s).	Methanol	259-267	prothrombin	Oryctolagus cuniculus	46-54
2822029-1	1987	Stimulation of human or rabbit platelets with thrombin in the presence of fibrinogen caused a large decrease, compared with unstimulated controls, in the amount of phosphatidylinositol 4,5-bisphosphate (PIP2) that could be extracted with acidified chloroform/methanol (60% at 60 s).	Methanol	259-267	fibrinogen beta chain	Homo sapiens	74-84
3619923-1	1987	A mixture of cholesterol autoxidation products, prepared from an aged sample of cholesterol by recrystallization from methanol, inhibits calmodulin irreversibly in a Ca2+-dependent reaction.	Methanol	118-126	calmodulin	Oryctolagus cuniculus	137-147
3580135-3	1987	A new method was developed to measure rates of H2O2 generation based on the fact that methanol is oxidized only by catalase in rat liver.	Methanol	86-94	catalase	Rattus norvegicus	115-123
3828998-7	1987	In cultured Exo-1 positive tumor cells the antigen was not demonstrable on the cell surface but in the cytoplasm after acetone/methanol fixation only.	Methanol	127-135	exonuclease 1	Homo sapiens	12-17
3805022-1	1987	The ligatin monomer is a polypeptide of Mr = 10,000 which is soluble in acidified chloroform:methanol, a characteristic similar to that of Folch-Lee proteolipid.	Methanol	93-101	ligatin	Homo sapiens	4-11
3803300-10	1987	The concentrations of CCK in methanol extracts of the duodenum and jejunum remained relatively constant, but those in acid extracts fell by 40% in the fasted animals.	Methanol	29-37	cholecystokinin	Rattus norvegicus	22-25
3502665-3	1987	Bone culture derived-TGF beta-like activity was soluble in 1.0 M acetic acid, eluted from Sephadex G-75 at relative molecular mass (Mr) 25,000, from mu Bondapak C18 rpHPLC at 63 +/- 5% methanol in 0.1 M acetic acid, and from mu Bondapak CN rpHPLC at 36 +/- 2% n-propanol in 0.1% trifluoroacetic acid.	Methanol	185-193	transforming growth factor, beta 1	Rattus norvegicus	21-29
3031209-3	1987	The monomeric heme octapeptide from cytochrome c, microperoxidase-8, (MP-8), coordinates CN- with log K = 7.55 +/- 0.04 at 25 degrees C in 20% (v/v) aqueous methanol.	Methanol	157-165	cytochrome c, somatic	Homo sapiens	36-48
3549752-2	1987	Up to 500 mg of raw insulin could be purified on a Nucleosil C8 analytical column using a methanol-containing phosphate buffer carrier and a cetrimide-containing displacer.	Methanol	90-98	insulin	Bos taurus	20-27
3801905-5	1986	CCK was extracted (90% methanol) from discrete brain regions (mouse) and quantified using the CCK RRA.	Methanol	23-31	cholecystokinin	Mus musculus	0-3
3302737-2	1987	The IgG fraction of anti-TdT serum is conjugated with fluoresceinisothiocyanate and used directly on the cytospin smears of methanol fixed bone marrow/blood smears.	Methanol	124-132	deoxynucleotidyltransferase, terminal	Mus musculus	25-28
2428402-2	1986	As previously observed for substance P in methanol, the core of physalaemin 4----8 is folded into an helical conformation.	Methanol	42-50	tachykinin precursor 1	Homo sapiens	27-38
3528285-2	1986	Methanol-5% glacial acetic acid in dry ice-fixed cell monolayers showed mainly intracellular FN staining.	Methanol	0-8	fibronectin 1	Mus musculus	93-95
3086321-10	1986	Interestingly, immunofluorescence studies indicate that only two monoclonal antibody groups (C and D) are able to decorate membrane-bound galactosyltransferase (Golgi-associated) in formalin-fixed, methanol-, or detergent-permeabilized cells.	Methanol	198-206	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Bos taurus	138-159
3766960-2	1986	The method, employing a C18 reverse-phase column eluted isocratically with a phosphoric acid-MeOH buffer, is linear over a range of 2 pmol to 20 nmol.	Methanol	93-97	Bardet-Biedl syndrome 9	Homo sapiens	24-27
3019241-1	1986	Catalase is an enzyme which can function either in the catabolism of hydrogen peroxide or in the peroxidatic oxidation of small substrates such as ethanol, methanol, or elemental mercury (Hg0).	Methanol	156-164	catalase	Homo sapiens	0-8
3005917-3	1986	Plasma beta-EP was evaluated by RIA previous beta-lipotropin stripping and Sep-Pack cartridge methanol extraction.	Methanol	94-102	proopiomelanocortin	Homo sapiens	7-14
3459148-3	1986	The spectrum of bound Mel is obtained directly from the spectrum of the [2H]CaM X Mel complex and is found to resemble strongly the spectrum of the helical species in methanol rather than that of the random coil species in water.	Methanol	167-175	calmodulin 2	Gallus gallus	76-79
3009301-1	1986	Red cell acid phosphatase (ACP1) catalyses the transfer of phosphate from phosphate ester substrates to suitable acceptor alcohols such as methanol and glycerol.	Methanol	139-147	acid phosphatase 1	Homo sapiens	27-31
3723354-4	1986	The beta m values, which are intended to apply to self-associated compounds when acting as "monomer" solutes, are: methanol, 0.42; all primary alkanols, 0.45; all secondary alkanols, 0.51; and all tertiary alkanols, 0.57.	Methanol	115-123	ATPase Na+/K+ transporting family member beta 4	Homo sapiens	4-10
2936535-2	1986	hANP from 5 mL of EDTA-treated plasma was adsorbed onto Sep-Pak C18 cartridges, which were eluted with methanol/trifluoroacetic acid (5 mL/L), 90/10 by volume.	Methanol	103-111	natriuretic peptide A	Homo sapiens	0-4
4093520-1	1985	Free carboxyl groups of bovine beta-lactoglobulin were esterified with methanol, ethanol, and n-butanol.	Methanol	71-79	beta-lactoglobulin	Bos taurus	31-49
3954332-2	1986	In contrast, chloroform/methanol extracted 3T3 cells inhibited the plating efficiency of neuroblastoma cells to the same extent as had been the case with living 3T3 cells.	Methanol	24-32	Rho guanine nucleotide exchange factor (GEF) 16	Mus musculus	89-102
3091949-1	1986	TdT as an intranuclear enzyme mainly of immature lymphoid cells is commonly determined immunologically using air-dried cell smears fixed with methanol.	Methanol	142-150	DNA nucleotidylexotransferase	Homo sapiens	0-3
2869658-1	1985	Acidic chloroform-methanol soluble proteins possessing hydrophobic properties and capable of inhibiting in vitro transcriptase activity of influenza virus RNP were detected in native and partially purified human leukocyte interferon (IFN) preparations.	Methanol	18-26	interferon alpha 1	Homo sapiens	212-238
4093520-13	1985	Use of the hydroxamic acid reaction made it possible to estimate the apparent extent of carboxyl modification of beta-lactoglobulin through esterification with methanol, ethanol, and n-butanol.	Methanol	160-168	beta-lactoglobulin	Bos taurus	113-131
2868691-6	1985	Additionally, the toxin was resistant to high concentrations of salt (8 M NaBr), organic solvents (40% methanol), denaturants (4 M urea), and neutral detergents (10% Triton X-100).	Methanol	103-111	pBt054	Bacillus thuringiensis serovar israelensis	18-23
2999442-2	1985	In indirect immunofluorescence assays, the rabbit anti-BMRF1 antiserum gave nuclear staining in approximately 5% of Raji cells which had been treated with sodium butyrate, and positive fluorescence was observed in both acetone- and methanol-fixed cells.	Methanol	232-240	BMRF1	Human gammaherpesvirus 4	55-60
4089878-2	1985	In the present report, cyanamide was shown to inhibit the peroxidatic activity of catalase with alcohols such as ethanol or methanol.	Methanol	124-132	catalase	Homo sapiens	82-90
4067921-5	1985	All the embryo-derived PAF was found in the chloroform fraction after chloroform:methanol (2:1 v/v) extraction, as was PAF-acether.	Methanol	81-89	patchy fur	Mus musculus	23-26
3904277-4	1985	When this material, concentrated 5-fold, was tested again, the culture filtrates and methanol-soluble fractions from all STa-producing strains yielded strongly positive fluid accumulation in the RILT, whereas culture filtrates and their methanol extracted fractions from the strains producing only STb, like methanol-insoluble fractions from four STa-producing strains, caused slight fluid secretion in the rabbit intestinal loops.	Methanol	85-93	GCY	Homo sapiens	121-124
3936852-5	1985	Indirect fluorescent, radio- and peroxidase immunobinding assays with intact and methanol-permeabilized cells confirmed that antigens PL-1 and PL-4 were exclusively intracellular and that well-washed phagolysosomes bound both antibodies.	Methanol	81-89	prolactin family 3, subfamily D, member 1	Rattus norvegicus	134-147
4015675-2	1985	The formation of 1,4-naphthoquinone, the major methanol-soluble product at early time points, showed an almost total dependence on cytochrome P-450, NADPH-cytochrome P-450 reductase and NADPH, and to a lesser extent on dilauroylphosphatidylcholine.	Methanol	47-55	cytochrome p450 oxidoreductase	Homo sapiens	149-181
3904277-0	1985	Comparison between enterotoxic activity and methanol solubility in heat-stable enterotoxins (STa and STb) from Escherichia coli of human, porcine and bovine origins.	Methanol	44-52	GCY	Homo sapiens	93-96
3904277-2	1985	Unconcentrated culture filtrates and methanol-soluble fractions from the eight STa-producing strains were positive in the IMT while methanol-insoluble fractions obtained from these STa-positive strains, like methanol-soluble and -insoluble fractions from the two strains producing only STb, lacked activity in the IMT.	Methanol	37-45	GCY	Homo sapiens	79-82
4015675-2	1985	The formation of 1,4-naphthoquinone, the major methanol-soluble product at early time points, showed an almost total dependence on cytochrome P-450, NADPH-cytochrome P-450 reductase and NADPH, and to a lesser extent on dilauroylphosphatidylcholine.	Methanol	47-55	2,4-dienoyl-CoA reductase 1	Homo sapiens	149-154
6508846-7	1984	When purified catalase and ascorbate were used, complex I was detected and methanol was oxidized.	Methanol	75-83	catalase	Cavia porcellus	14-22
4041237-1	1985	Proteolipid protein (PLP) was isolated from white matter of human brain by chloroform/methanol extraction and further purified by chromatography.	Methanol	86-94	proteolipid protein 1	Homo sapiens	0-25
17007768-1	1985	The solvophobic theory developed earlier by Sinanoglu introducing the use of molecular surface areas and microthermodynamic surface and interfacial tensions at molecular dimensions is applied to the interpretation of calorimetric data on denaturation of lysozyme in a wide range of methanol/water mixtures.	Methanol	282-290	lysozyme	Homo sapiens	254-262
4034415-1	1985	Fractionation on Sephadex G50 gel of methanol extracts of guinea pig intestine reveals two molecular forms of cholecystokinin (CCK) of about equal abundance.	Methanol	37-45	cholecystokinin	Cavia porcellus	110-125
3882834-5	1985	TdT positivity was preserved for more than 3 years in cells stored in suspension at -70 degrees C, and at least 76 days on slide preparations when fixed with methanol prior to freezing.	Methanol	158-166	DNA nucleotidylexotransferase	Homo sapiens	0-3
2983881-2	1985	The ESR spectra of biradicals in methanol have nine hyperfine resonance lines.	Methanol	33-41	esterase 5 regulator	Mus musculus	4-7
4015675-1	1985	1-Naphthol was metabolised by a fully reconstituted cytochrome P-450 system in the presence of NADPH to methanol-soluble and covalently bound products.	Methanol	104-112	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	52-68
4015675-1	1985	1-Naphthol was metabolised by a fully reconstituted cytochrome P-450 system in the presence of NADPH to methanol-soluble and covalently bound products.	Methanol	104-112	2,4-dienoyl-CoA reductase 1	Homo sapiens	95-100
4015675-2	1985	The formation of 1,4-naphthoquinone, the major methanol-soluble product at early time points, showed an almost total dependence on cytochrome P-450, NADPH-cytochrome P-450 reductase and NADPH, and to a lesser extent on dilauroylphosphatidylcholine.	Methanol	47-55	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	131-147
18553530-0	1984	Bacterial SCP from methanol in Kuwait: Product revovery and composition.	Methanol	19-27	urocortin 3	Homo sapiens	10-13
6098279-3	1984	A mixture of the ACTH fragments 1-4, 5-12, 13-24, 5-24, and 1-24 has been resolved on a Zorbax C8 column using methanol - 0,01 M tetrabutylammonium bromide (94:6) as mobile phase.	Methanol	111-119	proopiomelanocortin	Homo sapiens	17-21
6147254-3	1984	Initial formation rates of carbinol suggested Michaelis-Menten kinetics with an apparent KM of 61 and 171 mumol l-1 and Vmax of 3.2 and 5.8 nmol mg-1 microsomal protein h-1 in two human liver samples.	Methanol	27-35	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	145-149
6469902-4	1984	C16 and C18:1 co-elute in the acetonitrile-water system but are separated using an isocratic methanol-acetonitrile-water system.	Methanol	93-101	Bardet-Biedl syndrome 9	Homo sapiens	8-11
6147254-4	1984	The Vmax in microsomes of thirty-two liver samples was 4.2 +/- 1.0 (SD) nmol carbinol mg-1 protein h-1.	Methanol	77-85	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	86-90
6147254-6	1984	Microsomes of one individual identified as poor metabolizer of debrisoquine in vivo showed reduction of carbinol formation to 1.97 nmol mg-1 h-1.	Methanol	104-112	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	136-140
6319393-11	1984	Subsequent spontaneous reactions, including the elimination of methanol and the opening of the aziridine ring, generate one active center at C-1 which facilitates nucleophilic attack.	Methanol	63-71	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	141-144
6371049-1	1984	The DNA hybridization assay employing a 460-base-pair fragment of DNA encoding for the methanol-insoluble form of heat-stable toxin (ST-II) was used to determine the prevalence of ST-II enterotoxigenic Escherichia coli (ETEC) in pigs, people, and water at 57 farms in Sri Racha, Thailand.	Methanol	87-95	ETEC	Sus scrofa	220-224
6319607-5	1984	Using a mobile phase of 0.15 M sodium acetate-20% methanol (pH 5.0) at a flow rate of 4 ml/min, cAMP is eluted at k" greater than 1.25, whereas k" less than 0.5 for all other adenine nucleotides, permitting collection of the cAMP fraction after running the other nucleotides to waste.	Methanol	50-58	cathelicidin antimicrobial peptide	Rattus norvegicus	96-100
6199600-7	1984	It is concluded that the partial agonistic activity of bufuralol and its carbinol metabolite is exerted mainly at the beta 2-adrenoceptor, producing vasodilation and reducing peripheral resistance, resulting in a reduction in blood pressure with a long duration of action.	Methanol	73-81	beta-2 adrenergic receptor	Canis lupus familiaris	118-137
6748292-0	1984	[Effect of a fraction of methanol extraction of licorice root on release of secretin in humans].	Methanol	25-33	secretin	Homo sapiens	76-84
6660850-3	1983	The 10-micron C18 muBondapak column was eluted with 45% (vol/vol) methanol-65% (vol/vol) phosphate buffer.	Methanol	66-74	Bardet-Biedl syndrome 9	Homo sapiens	14-17
6424274-2	1984	A mobile phase of methanol:water (35:65) passed through a mu-Bondapak C-18 column at a rate of 1.0 ml/min produced a sharp, symmetrical band for mitomycin C.	Methanol	18-26	Bardet-Biedl syndrome 9	Homo sapiens	70-74
6661246-7	1983	The half-life of DES quinone in water was approximately 40 min; in methanol it was approximately 70 min.	Methanol	67-75	desmin	Rattus norvegicus	17-20
6309521-1	1983	The binding of nerve growth factor (NGF) to its receptors in PC12 cells was studied in two experimental conditions: (a) cell fixation with paraformaldehyde followed by permeabilization of the plasma membrane with methanol and (b) metabolic poisoning of living cells with sodium azide.	Methanol	213-221	nerve growth factor	Rattus norvegicus	15-34
6420457-2	1983	TRH was measured by radioimmunoassay of methanol extracts of blood.	Methanol	40-48	thyrotropin releasing hormone	Rattus norvegicus	0-3
6419374-2	1983	Incubation of PRP with EOG, either in methanol or in homologous PPP, inhibits platelet aggregation induced by all of the above mentioned agonists.	Methanol	38-46	prion protein	Homo sapiens	14-17
6309521-1	1983	The binding of nerve growth factor (NGF) to its receptors in PC12 cells was studied in two experimental conditions: (a) cell fixation with paraformaldehyde followed by permeabilization of the plasma membrane with methanol and (b) metabolic poisoning of living cells with sodium azide.	Methanol	213-221	nerve growth factor	Rattus norvegicus	36-39
6309521-2	1983	Paraformaldehyde fixation of PC12 cells causes a 60-70% reduction of NGF binding capacity; the original binding capacity is restored following permeabilization with methanol.	Methanol	165-173	nerve growth factor	Rattus norvegicus	69-72
7161327-1	1982	A specific method is presented for the assay of leucine-enkephalin (Leu-Enk) and its metabolites by reversed-phase high-performance liquid chromatography on a muBondapak C18 column with a mobile phase of methanol-water and 0.005 M tetrabutylammonium phosphate.	Methanol	204-212	proenkephalin	Rattus norvegicus	72-75
6226318-4	1983	The Arrhenius plots for ATPase revealed bends at 20 degrees and 30 degrees C in the presence of sulphite, chlorine, thiocyanate, glycerol and methanol.	Methanol	142-150	dynein, axonemal, heavy chain 8	Mus musculus	24-30
6308024-5	1983	LiChrosorb RP-18, Nucleosil C18 and muBondapak C18 gave rise to different selectivities when an acidic eluent, methanol-water (25:75) containing 0.2% of 1.8 M H2SO4 was used.	Methanol	111-119	Bardet-Biedl syndrome 9	Homo sapiens	28-31
6308024-5	1983	LiChrosorb RP-18, Nucleosil C18 and muBondapak C18 gave rise to different selectivities when an acidic eluent, methanol-water (25:75) containing 0.2% of 1.8 M H2SO4 was used.	Methanol	111-119	Bardet-Biedl syndrome 9	Homo sapiens	47-50
6868653-2	1983	Demonstration of the lysogenic state of the facultative methanol-assimilating strain of Acetobacter MB 58/1 and characterization of its temperate phage MO 1].	Methanol	56-64	CD79a molecule	Homo sapiens	100-107
6226318-0	1983	[Mechanism of glycerol and methanol action on soluble ATPase of mitochondria].	Methanol	27-35	dynein, axonemal, heavy chain 8	Mus musculus	54-60
6226318-1	1983	The effects of methanol, butanol, glycerol, glucose, sucrose and inorganic anions on the activity of soluble ATPase from mouse liver mitochondria were studied.	Methanol	15-23	dynein, axonemal, heavy chain 8	Mus musculus	109-115
6226318-3	1983	Glycerol-induced inhibition of ATPase was competitive with respect to sulphite; methanol competed with thiocyanate for the enzyme activity.	Methanol	80-88	dynein, axonemal, heavy chain 8	Mus musculus	31-37
6306272-4	1983	The other two monoclonal antibodies, designated K8 and K9, reacted with a methanol-sensitive restricted component of this complex.	Methanol	74-82	keratin 8	Homo sapiens	48-57
6304007-12	1983	A methanol dehydrogenase mutant, M15A, was unable to take up methanol.	Methanol	2-10	MEXAM1_RS21720	Methylobacterium extorquens AM1	11-24
6304007-13	1983	It is proposed that methanol diffuses into the cell where it is rapidly oxidized by methanol dehydrogenase.	Methanol	20-28	MEXAM1_RS21720	Methylobacterium extorquens AM1	93-106
6223667-4	1983	The original Mg2+-dependent activity of CF1-ATPase is close to that observed under steady-state conditions in the presence of sulphate and methanol and exceeds the Ca2+-dependent activity approximately 6-fold.	Methanol	139-147	mucolipin TRP cation channel 1	Homo sapiens	13-16
6223667-4	1983	The original Mg2+-dependent activity of CF1-ATPase is close to that observed under steady-state conditions in the presence of sulphate and methanol and exceeds the Ca2+-dependent activity approximately 6-fold.	Methanol	139-147	dynein axonemal heavy chain 8	Homo sapiens	44-50
6838195-1	1983	Mixed-solvent systems of methanol and other alcohols and water were used to study the properties of bovine phenylethanolamine-N-methyltransferase.	Methanol	25-33	phenylethanolamine N-methyltransferase	Bos taurus	107-145
6629593-0	1983	Oral administration of the methanol extraction residue of BCG (MER/BCG): a phase I study in non-oat cell lung cancer patients.	Methanol	27-35	MER proto-oncogene, tyrosine kinase	Homo sapiens	63-66
7171573-1	1982	The hydrolysis of L-leucine-p-nitroanilide by porcine kidney leucine aminopeptidase in aqueous mixed-solvent systems containing methanol, ethanol, dimethyl sulfoxide, and dimethylformamide has been investigated in the -30 to -23 degrees C temperature range.	Methanol	128-136	carboxypeptidase Q	Homo sapiens	69-83
7155031-9	1982	We recommend further studies to determine if any of the constituents of betel nut diminish the toxic effects of methanol on the eye.	Methanol	112-120	NUT midline carcinoma family member 1	Homo sapiens	78-81
7138825-1	1982	The refolding of ribonuclease A (RNase A) has been investigated in aqueous methanol cryosolvents in the 0 to -20 degrees C range.	Methanol	75-83	ribonuclease A family member 1, pancreatic	Homo sapiens	17-31
7138825-1	1982	The refolding of ribonuclease A (RNase A) has been investigated in aqueous methanol cryosolvents in the 0 to -20 degrees C range.	Methanol	75-83	ribonuclease A family member 1, pancreatic	Homo sapiens	33-40
6175874-1	1982	Two preparations of myelin basic protein (MBP) were derived from an acid excretion of chloroform-methanol defatted bovine spinal cord.	Methanol	97-105	myelin basic protein	Bos taurus	20-40
6181041-0	1982	A prospective controlled evaluation of combined pelvic radiotherapy and methanol extraction residue of BCG (MER) for locally unresectable or recurrent rectal carcinoma.	Methanol	72-80	MER proto-oncogene, tyrosine kinase	Homo sapiens	108-111
6282362-8	1982	Thin-layer chromatography analysis of chloroform-methanol extracts showed substances that comigrated with authentic 5-hydroxyeicosatetraenoic acid had a marked increase in radioactivity following PAF stimulation at 10(-7) M. PAF failed to stimulate release of granule enzymes, B-glucuronidase, lysozyme, or myeloperoxidase unless cytochalasin-B were added.	Methanol	49-57	PCNA clamp associated factor	Homo sapiens	196-199
6282362-8	1982	Thin-layer chromatography analysis of chloroform-methanol extracts showed substances that comigrated with authentic 5-hydroxyeicosatetraenoic acid had a marked increase in radioactivity following PAF stimulation at 10(-7) M. PAF failed to stimulate release of granule enzymes, B-glucuronidase, lysozyme, or myeloperoxidase unless cytochalasin-B were added.	Methanol	49-57	PCNA clamp associated factor	Homo sapiens	225-228
6282362-8	1982	Thin-layer chromatography analysis of chloroform-methanol extracts showed substances that comigrated with authentic 5-hydroxyeicosatetraenoic acid had a marked increase in radioactivity following PAF stimulation at 10(-7) M. PAF failed to stimulate release of granule enzymes, B-glucuronidase, lysozyme, or myeloperoxidase unless cytochalasin-B were added.	Methanol	49-57	myeloperoxidase	Homo sapiens	277-322
7068676-9	1982	A. sialophilus neuraminidase further catalyzes transglycosidation reactions with methanol as acceptor.	Methanol	81-89	neuraminidase 1	Homo sapiens	15-28
6175874-1	1982	Two preparations of myelin basic protein (MBP) were derived from an acid excretion of chloroform-methanol defatted bovine spinal cord.	Methanol	97-105	myelin basic protein	Bos taurus	42-45
7057195-1	1982	Angiotensin II-like immunoreactivity was extracted from brains of bilaterally nephrectomized rats with several different extraction procedures (90% methanol, distilled water, 6 M urea, 0.1 N HCl, and 2 M acetic acid).	Methanol	148-156	angiotensinogen	Rattus norvegicus	0-14
7128475-2	1982	Chloramphenicol, an inhibitor of cytochrome P-450, blocked the increase of serum glutamate-oxaloacetate transaminase activity enhanced by methanol pretreatment of rats exposed to CCl4.	Methanol	138-146	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	33-49
7066349-3	1982	However, the stabilizing effect on lipoprotein lipase was reduced by 60-70% by the extraction of cells with chloroform/methanol (2:1).	Methanol	119-127	lipoprotein lipase	Bos taurus	35-53
6280725-0	1982	Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes.	Methanol	59-67	catalase	Rattus norvegicus	8-16
6280725-1	1982	In view of the presence of adventitious catalase in isolated microsomes, and the requirement for H2O2, it has been suggested that NADPH-dependent oxidation of methanol by rat liver microsomes was mediated exclusively by the peroxidatic activity of catalase.	Methanol	159-167	catalase	Rattus norvegicus	40-48
6280725-1	1982	In view of the presence of adventitious catalase in isolated microsomes, and the requirement for H2O2, it has been suggested that NADPH-dependent oxidation of methanol by rat liver microsomes was mediated exclusively by the peroxidatic activity of catalase.	Methanol	159-167	catalase	Rattus norvegicus	248-256
6280725-5	1982	In the absence of the catalase inhibitor azide, methanol may be oxidized primarily by the peroxidatic activity of catalase since there was little effect on methanol oxidation by competing hydroxyl radical scavengers.	Methanol	48-56	catalase	Rattus norvegicus	114-122
7149697-0	1982	Features of a Clostridium, strain CV-AA1, an obligatory anaerobic bacterium producing acetic acid from methanol.	Methanol	103-111	AA1	Homo sapiens	37-40
7128475-0	1982	Modification of methanol potentiation of CCl4 toxicity in rats by chloramphenicol and salicylate.	Methanol	16-24	C-C motif chemokine ligand 4	Rattus norvegicus	41-45
7128475-1	1982	The mechanisms by which methanol potentiates CCl4 hepatotoxicity was studied in rats.	Methanol	24-32	C-C motif chemokine ligand 4	Rattus norvegicus	45-49
6280725-6	1982	Azide, which inhibited catalase activity greater than 95%, inhibited NADPH-dependent oxidation of methanol by 30-50%.	Methanol	98-106	catalase	Rattus norvegicus	23-31
6280725-7	1982	The azide-insensitive (catalase-independent) pathway of methanol oxidation was inhibited by scavengers of hydroxyl radicals.	Methanol	56-64	catalase	Rattus norvegicus	23-31
6280725-12	1982	These results suggest that in microsomes, depending on the absence or presence of azide, methanol may be oxidized by two primary pathways, one involving the peroxidatic activity of catalase, and the other in which hydroxyl radicals, generated from microsomal electron transfer, play a role.	Methanol	89-97	catalase	Rattus norvegicus	181-189
7038686-3	1982	The decoration of either structure depends on the fixation and permeabilization conditions: MFs, in the form of stress fibers, are stained by NGF when the plasma membrane is permeabilized with methanol/acetone; MTs become intensely stained when the plasma membrane is solubilized with a nonionic detergent in the presence of a MT-stabilizing medium.	Methanol	193-201	nerve growth factor	Homo sapiens	142-145
7128475-2	1982	Chloramphenicol, an inhibitor of cytochrome P-450, blocked the increase of serum glutamate-oxaloacetate transaminase activity enhanced by methanol pretreatment of rats exposed to CCl4.	Methanol	138-146	C-C motif chemokine ligand 4	Rattus norvegicus	179-183
7128475-4	1982	Chloramphenicol prevented the loss of glucose 6-phosphatase activity after CCl4 and methanol.	Methanol	84-92	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	38-59
7128475-5	1982	Sodium salicylate, which lowers the level of NADPH in the hepatocyte, blocked methanol potentiation of CCl4 damage as measured by the elevation of serum GOT activity.	Methanol	78-86	C-C motif chemokine ligand 4	Rattus norvegicus	103-107
7128475-6	1982	Therefore, methanol may potentiate CCl4 hepatotoxicity by stimulation of CCl4 bioactivation by cytochrome P-450 via an increase in the level of reduced NAD(P)H in the liver.	Methanol	11-19	C-C motif chemokine ligand 4	Rattus norvegicus	35-39
7128475-6	1982	Therefore, methanol may potentiate CCl4 hepatotoxicity by stimulation of CCl4 bioactivation by cytochrome P-450 via an increase in the level of reduced NAD(P)H in the liver.	Methanol	11-19	C-C motif chemokine ligand 4	Rattus norvegicus	73-77
7128475-6	1982	Therefore, methanol may potentiate CCl4 hepatotoxicity by stimulation of CCl4 bioactivation by cytochrome P-450 via an increase in the level of reduced NAD(P)H in the liver.	Methanol	11-19	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	95-111
16345884-6	1981	Anaerobic treatment of RDX wastewaters, which also contain high nitrate levels, would permit the denitrification to occur, with concurrent degradation of RDX ultimately to a mixture of hydrazines and methanol.	Methanol	200-208	radixin	Homo sapiens	23-26
7347821-3	1981	A significant difference was evidenced between AST and ALT levels in two firms, chiefly attributable to the quantity and quality of the substances utilized in the two technological cycles: trichloroethylene, chromium, sulphuric acid, mineral oils, ammonia, N-hexane, pentanes acetone, ciclo hexane, methanol, ethyl acetate, isopropyl acetate, toluene, methylene chloride.	Methanol	299-307	solute carrier family 17 member 5	Homo sapiens	47-50
7187061-1	1982	The effect of 1-propanol, 2-propanol, n-butanol, ethanol and methanol an sorbitol dehydrogenase activity was assayed.	Methanol	61-69	sorbitol dehydrogenase	Homo sapiens	73-95
7157404-10	1982	Methanol treated (4 g/kg) Csb-FAD mice excreted 30.8-48.2% of the oral dose as urinary formate, depending on the level of dietary methionine.	Methanol	0-8	excision repair cross-complementing rodent repair deficiency, complementation group 6	Mus musculus	26-29
7157404-14	1982	Since the Csb-FAD mouse attains high plasma formate levels and low blood pH-values similar to those which have been reported for methanol poisoned monkeys, it appears to be of value as an inexpensive small animal model for further studies of lethal methanol toxicity and the contribution of formate to this process.	Methanol	249-257	excision repair cross-complementing rodent repair deficiency, complementation group 6	Mus musculus	10-13
6271757-1	1981	The heme propionates of heme peptide 1-25 from horse heart cytochrome c were methylated in acidified methanol.	Methanol	101-109	cytochrome c, somatic	Equus caballus	59-71
6281205-2	1981	The alpha-helix content of human beta-endorphin (beta h-EP) has been determined by circular dichroism (CD) in solutions ranging from 0 to 95% methanol in water.	Methanol	142-150	proopiomelanocortin	Homo sapiens	33-47
7336957-9	1981	Since methanol prevented the pyrazole-induced decrease in brain catalase activity, we can also rule out the possibility that the decrease in brain noradrenaline is secondary to pyrazole-induced inhibition of brain catalase.	Methanol	6-14	catalase	Mus musculus	64-72
6266642-0	1981	Combination chemotherapy with and without the methanol-extracted residue of bacillus Calmette-Guerin (MER) in extensive non-small-cell lung cancer: a prospective randomized study for the Piedmont Oncology Association.	Methanol	46-54	MER proto-oncogene, tyrosine kinase	Homo sapiens	102-105
7226124-0	1981	Chemotherapy vs. chemoimmunotherapy with methanol extraction residue of Bacillus Calmette-Guerin (MER) in advanced breast cancer: a randomized trial by the Piedmont Oncology Association.	Methanol	41-49	MER proto-oncogene, tyrosine kinase	Homo sapiens	98-101
6165977-8	1981	Gel filtration studies of the methanol extracts of human and dog plasma indicated that an immunoreactive motilin-like material with a molecular size similar to natural porcine motilin was measured by our routine radioimmunoassay.	Methanol	30-38	motilin	Canis lupus familiaris	105-112
7205659-3	1981	Nitrous oxide treatment was used to inhibit 5-methyltetrahydrofolate homocysteine methyltransferase (methionine synthetase, EC 4.2.99.10) in order to delineate the role of this enzyme in regulating the metabolism of formate in rats and in determining the sensitivity of this species to methanol intoxication.	Methanol	286-294	5-methyltetrahydrofolate-homocysteine methyltransferase	Rattus norvegicus	44-99
6283818-0	1981	Effects of methanol and chloramphenicol on CCl4 toxicity.	Methanol	11-19	C-C motif chemokine ligand 4	Homo sapiens	43-47
6780584-0	1981	Prolactin-releasing activity in methanol extracts of human plasma: problems with the bioassay of this activity.	Methanol	32-40	prolactin	Homo sapiens	0-9
6249481-7	1980	Methanol extract residue of BCG (MER) was administered IV to 20 of 39 patients receiving vindesine without randomization in order to evaluate toxicities associated with IV MER.	Methanol	0-8	MER proto-oncogene, tyrosine kinase	Homo sapiens	33-36
16345659-1	1980	Strain DM1, a facultative methylotrophic bacterium utilizing methanol, formate, mono-, di-, and trimethylamine, as well as dichloromethane as C1 substrates was isolated as an airborne contaminant.	Methanol	61-69	immunoglobulin heavy diversity 1-7	Homo sapiens	7-10
7002629-1	1980	Plasma levels of immunoreactive luteinizing hormone-releasing hormone (LH-RH) in 89 women with normal menstrual cycles and 109 patients with amenorrhea of various etiologies were determined by specific radioimmunoassay after methanol extraction.	Methanol	225-233	gonadotropin releasing hormone 1	Homo sapiens	32-69
6258570-3	1980	Pure methanol dehydrogenase reduced cytochrome c (in the absence of methanol) by lowering the pK for autoreduction to less than 8.5.	Methanol	5-13	MEXAM1_RS21720	Methylobacterium extorquens AM1	14-27
6258570-3	1980	Pure methanol dehydrogenase reduced cytochrome c (in the absence of methanol) by lowering the pK for autoreduction to less than 8.5.	Methanol	5-13	MEXAM1_RS12150	Methylobacterium extorquens AM1	36-48
7188860-0	1980	Purificaton and characterization of S-formylglutathione hydrolase from a methanol-utilizing yeast, Kloeckera sp.	Methanol	73-81	S-formylglutathione hydrolase	Saccharomyces cerevisiae S288C	36-65
6776180-2	1980	The TRH-like material was extracted with methanol and was found to be indistinguishable from synthetic TRH in its immunoreactivity and bioreactivity and in its proteolytic degradation by fresh human serum.	Methanol	41-49	thyrotropin releasing hormone	Homo sapiens	4-7
7378472-2	1980	The 15N-NMR data obtained in chloroform and methanol are reported for Boc-L-Val1-L-Pro2-Gly3-Gly4-OMe, a repeat tetrapeptide sequence of tropoelastin.	Methanol	44-52	elastin	Homo sapiens	137-149
7430045-4	1980	The fat is eluted on a glass column, using dichloromethane-methanol (9+1).	Methanol	59-67	FAT atypical cadherin 1	Homo sapiens	4-7
503871-2	1979	Carbon 11-labeled HCN was collected in methanol containing carrier NaCN following bombardment of 99% N2-1% H2 with 22 MeV protons.	Methanol	39-47	cyclic nucleotide gated channel subunit alpha 1	Rattus norvegicus	18-21
7445911-0	1980	A method based on the use of methanol as a stabilizing agent to prepare metal-free glyoxalase I and to reconstitute activity by addition of bivalent metal ions.	Methanol	29-37	glyoxalase I	Homo sapiens	83-95
549628-6	1979	Conditions which abolished the break enabled endogenous cardiolipin to be removed from the enzyme by chloroform/methanol extraction Cardiolipin from acetylcholinesterase incubated in high salt in Ca2+ -chelating conditions was not accessible to digestion by phospholipase A2, and was not separated from the enzyme by flotation in a sucrose density gradient or by Sephadex G-200 chromatography.	Methanol	112-120	acetylcholinesterase	Bos taurus	149-169
227369-5	1979	During carbon-limited growth on methanol or succinate some cytochrome c was tightly bound to bacterial membranes, whereas none was tightly bound in bacteria grown in batch-culture or in NH(4) (+)-limited conditions.	Methanol	32-40	MEXAM1_RS12150	Methylobacterium extorquens AM1	59-71
458815-2	1979	Low-energy conformers of carbinol substituents on C7-C19-R1R2OH are found with and without intramolecular hydrogen bonding to the C6-OCH3 group.	Methanol	25-33	complement C6	Homo sapiens	130-143
427107-1	1979	The thermal denaturation of lysozyme was studied at pH 2 in aqueous mixtures of methanol, ethanol, and 1-propanol by high sensitivity differential scanning calorimetry (DSC).	Methanol	80-88	lysozyme	Homo sapiens	28-36
222335-1	1979	We have studied the reaction of ferricytochrome c, methemoglobin and metmyoglobin with OH and alcohol radicals (methanol, ethanol, ethylene glycol and glycerol).	Methanol	112-120	hemoglobin subunit gamma 2	Homo sapiens	51-64
479083-5	1979	In 5 of the 6 samples containing aflatoxins B1, B2, G1, and G2, methanol-10% NaCl extracted more aflatoxin than did cloroform-water, as measured both by HPLC and by thin layer chromatography.	Methanol	64-72	anthocyanin regulatory R-S protein-like	Zea mays	44-62
154924-5	1979	These data can be interpreted to imply that the catalytic and regulatory sites of the mitochondrial ATPase are being dissociated 20% methanol.	Methanol	133-141	dynein axonemal heavy chain 8	Homo sapiens	100-106
114870-1	1979	Methanol extracts of rat plasma resulted in release of prolactin (PRL) from rat hemipituitaries in vitro with a linear log-dose relationship.	Methanol	0-8	prolactin	Rattus norvegicus	55-64
154924-8	1979	These data are interpreted to indicate that an acidic group in the active site may be ionizing, limiting the ATPase-catalyzed hydrolytic rate, and, with 20% methanol, this ionization was inhibited.	Methanol	157-165	dynein axonemal heavy chain 8	Homo sapiens	109-115
429090-6	1979	Oxytocin elutes with 33% MeOH-CHCl3.	Methanol	25-29	oxytocin/neurophysin I prepropeptide	Homo sapiens	0-8
31936-0	1979	Purification and properties of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from a methanol-utilizing yeast, Candida boidinii.	Methanol	109-117	glucose-6-phosphate dehydrogenase	Saccharomyces cerevisiae S288C	31-64
114870-1	1979	Methanol extracts of rat plasma resulted in release of prolactin (PRL) from rat hemipituitaries in vitro with a linear log-dose relationship.	Methanol	0-8	prolactin	Rattus norvegicus	66-69
117391-1	1979	Methanol extracts of several rat tissues (hypothalamus, amygdala, the rest of the forebrain, brain stem and pancreas) were partially purified in SP-cation exchange chromatography and measured in TRF radioimmunoassay.	Methanol	0-8	interleukin 5	Rattus norvegicus	195-198
32922-0	1978	[Spectral parameters of the cytochrome c and hemoglobin interaction with methanol and aniline].	Methanol	73-81	cytochrome c, somatic	Homo sapiens	28-40
728866-0	1978	Intralesional injection of the methanol extraction residue of Bacillus Calmette-Guerin (MER) into cutaneous metastases of malignant melanoma.	Methanol	31-39	MER proto-oncogene, tyrosine kinase	Homo sapiens	88-91
728866-1	1978	Twenty-two patients with cutaneous metastases of malignant melanoma were treated with intralesional injections of the methanol extraction residue of bacillus Calmette-Guerin (MER).	Methanol	118-126	MER proto-oncogene, tyrosine kinase	Homo sapiens	175-178
32922-1	1978	At 20 degrees C, in a phosphate buffer, pH 5,8--8,0, methanol and aniline interactions with hemoglobin and cytochrome c were studied using the difference spectrophotometry method.	Methanol	53-61	cytochrome c, somatic	Homo sapiens	107-119
708779-2	1978	The conformation of a hexapeptide sequence occurring in tropoelastin is discussed from the results obtained using a combined approach of theoretical conformational energy calculations on HCO-Val-Ala-Prb-Gly-OMe and 1h nmr studies on t-Boc-Val-Ala-Pro-Gly-Val-Gly-OMe  in a dilute solution of methanol.	Methanol	292-300	elastin	Homo sapiens	56-68
215685-3	1978	A total lipid extract is prepared from tissues with chloroform-methanol-KC1 or chloroform-methanol-HC1 and washed once with acidified methanol-water.	Methanol	90-98	CYCS pseudogene 39	Homo sapiens	99-102
32928-6	1978	The interaction of the alcohols with cytochrome P-450 in phosphate buffer pH = 6,0 in the detergents absence is characterized by one dissociation constant for MeOH, EtOH, n-BuOH and cyclohexanol and by two dissociation constants for i-PrOH, i-BuOH and tert.-BuOH.	Methanol	159-163	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	37-53
211030-1	1978	A pulse-radiolysis study of aqueous-methanol solutions of methemoglobin.	Methanol	36-44	hemoglobin subunit gamma 2	Homo sapiens	58-71
668701-0	1978	Purification and regulation of glucose-6-phosphate dehydrogenase from obligate methanol-utilizing bacterium Methylomonas M15.	Methanol	79-87	glucose-6-phosphate dehydrogenase	Homo sapiens	31-64
357288-2	1978	The toxins were separated by methanol extraction, and the first, STa, was methanol soluble, partially heat stable, active in neonatal piglets (1 to 3 days old) and infant mice, but inactive in weaned pigs (7 to 9 weeks old); the second, STb, was methanol insoluble, active in weaned pigs and rabbit ligated loops, but inactive in infant mice.	Methanol	29-37	GCY	Homo sapiens	65-68
357288-2	1978	The toxins were separated by methanol extraction, and the first, STa, was methanol soluble, partially heat stable, active in neonatal piglets (1 to 3 days old) and infant mice, but inactive in weaned pigs (7 to 9 weeks old); the second, STb, was methanol insoluble, active in weaned pigs and rabbit ligated loops, but inactive in infant mice.	Methanol	74-82	GCY	Homo sapiens	65-68
357288-2	1978	The toxins were separated by methanol extraction, and the first, STa, was methanol soluble, partially heat stable, active in neonatal piglets (1 to 3 days old) and infant mice, but inactive in weaned pigs (7 to 9 weeks old); the second, STb, was methanol insoluble, active in weaned pigs and rabbit ligated loops, but inactive in infant mice.	Methanol	74-82	GCY	Homo sapiens	65-68
204612-0	1978	Effects of prophylactic treatment with the methanol extraction residue fraction of tubercle bacilli (MER) on the development of Rous sarcomas of chickens following challenge with the Rous sarcoma virus.	Methanol	43-51	MER proto-oncogene, tyrosine kinase	Homo sapiens	101-104
656499-3	1978	Using methanol as an additional nucleophile, the kinetic parameters - k2, k3 and Ks - were measured for both thrombin- and trypsin-catalysed reactions.	Methanol	6-14	coagulation factor II, thrombin	Homo sapiens	109-117
27728-6	1978	At higher pH values (5.5) SP could be transferred from an aqueous phase into an organic phase (chloroform:methanol, 2:1) and recombined with TLE (which was previously freed from endogenous SP) contained in this phase.	Methanol	106-114	tachykinin precursor 1	Homo sapiens	26-28
25651-9	1978	The cytochrome c appears to be essential only for respiration and proton translocation from methanol (and possibly from methylamine); there is no conclusive evidence that cytochrome c ever mediates between cytochromes b and a/a(3) in Pseudomonas AM1.	Methanol	92-100	MEXAM1_RS12150	Methylobacterium extorquens AM1	4-16
204612-1	1978	Three-month-old chickens were treated with the methanol extraction residue fraction of tubercle bacilli (MER) under different conditions, and subsequently challenged with living Rous sarcoma virus.	Methanol	47-55	MER proto-oncogene, tyrosine kinase	Homo sapiens	105-108
336070-2	1977	MER (methanol extraction residue of BCG).	Methanol	5-13	MER proto-oncogene, tyrosine kinase	Homo sapiens	0-3
621271-2	1978	The methanol extract is subjected to a liquid-liquid cleanup at pH 13 and 1, further cleaned up on a silica gel column and assayed by high-pressure liquid chromatography by using an ultraviolet absorption detector at 210 nm.	Methanol	4-12	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	64-75
911990-2	1977	The CPL of each complex in methanol was found to be different than when in n-hexane.	Methanol	27-35	hephaestin	Homo sapiens	4-7
597668-3	1977	Elution with methanol separates the enkephalins and alpha-endorphin from beta-endorphin.2 Over 90% of the opioid peptide activity isolated from brain and gut of several species by our method was due to methionine- and leucine-enkephalin.	Methanol	13-21	proopiomelanocortin	Homo sapiens	73-87
604361-0	1977	Granuloma formation in patients after injection of methanol extraction residue (MER-GCG).	Methanol	51-59	glucagon	Homo sapiens	84-87
333843-1	1977	Highly specific and sensitive radioimmunological methods were applied to determine the levels of LH-RH like immunoreactivity in urine previously extracted by spherosil and methanol, and to assay the gonadotrophins, after extraction with acetone.	Methanol	172-180	gonadotropin releasing hormone 1	Homo sapiens	97-102
198206-12	1977	The C-1 configuration in (1S)-TRANS,TRANS-[1-3H1]farnesyl diphosphate and phosphate and (1R)-trans,trans-[1-3H1]farnesyl diphosphate and phosphate is progressively racemised in 0.01 M NH4OH/MeOH (1/9) AT - 20 degrees C.	Methanol	190-194	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	4-7
891779-2	1977	2 peaks of proteolipids eluted in chloroform-methanol 4/1 showed the binding capacity for C14 - 5-HT.	Methanol	45-53	anti-Mullerian hormone receptor type 2	Rattus norvegicus	90-93
890982-2	1977	After evaporating the ether and dissolving the residue in methanol, the bile acids are directly determined with 3 alpha-hydroxysteroid dehydrogenase.	Methanol	58-66	aldo-keto reductase family 1 member C3	Homo sapiens	112-148
882833-2	1977	Secretin to be measured was extracted into methanol from heparinized plasma containing aprotinin, which together with cysteine hydrochloride was used as stabilizer throughout the assay.	Methanol	43-51	secretin	Homo sapiens	0-8
880222-1	1977	Treatment of the chloroform/methanol-insoluble residue of rat brain myelin with lithium 3,5-di-iodosalicylate solubilized the major myelin-associated glycoprotein along with most other proteins and glycoproteins.	Methanol	28-36	myelin-associated glycoprotein	Rattus norvegicus	132-162
12008-0	1976	Methylmalonyl-CoA mutase in a methanol-utilizing bacterium.	Methanol	30-38	methylmalonyl-CoA mutase	Homo sapiens	0-24
823752-4	1976	The TRH was extracted from serum with methanol.	Methanol	38-46	thyrotropin releasing hormone	Homo sapiens	4-7
1069983-3	1976	Parallel proton and carbon relaxation measurements demonstrate that the anion (X-), sodium complex (NaX), and barium complex (BaX+) are also monomeric in methanol solution.	Methanol	154-162	BCL2 associated X, apoptosis regulator	Homo sapiens	126-129
1069983-6	1976	The exchange of lasalocid anion between free (X-) and complexed (BaX+) states in methanol can be monitored from the temperature-dependent line shapes of the proton resonances at superconducting fields.	Methanol	81-89	BCL2 associated X, apoptosis regulator	Homo sapiens	65-68
1069983-7	1976	The exchange rates are independent of the reactant concentrations and are characteristic of a rate-determining dissociation of BaX+ in methanol solution with activation parameters delta H++ = 6.5 kcal mol-1 (25 degrees) and delta S++ = -20.0 cal mol-1 degree -1 (1 cal = 4.184 J).	Methanol	135-143	BCL2 associated X, apoptosis regulator	Homo sapiens	127-130
1069983-8	1976	The rate constants for dissociation and formation of BaX+ complex in methanol, 25 degrees, are 5.2 X 10(3) sec-1 and 1.5 X 10(10) M-1 sec-1, respectively.	Methanol	69-77	BCL2 associated X, apoptosis regulator	Homo sapiens	53-56
1069983-8	1976	The rate constants for dissociation and formation of BaX+ complex in methanol, 25 degrees, are 5.2 X 10(3) sec-1 and 1.5 X 10(10) M-1 sec-1, respectively.	Methanol	69-77	secretory blood group 1, pseudogene	Homo sapiens	107-139
1069983-9	1976	These studies were extended to derive the activation parameters for the exchange of lasalocid anion between BaX+ and NaX and between BaX+ and HX in methanol, while the exchange among HX, X-, and NaX is too rapid to be monitored on the time scale of nuclear magnetic resonance.	Methanol	148-156	BCL2 associated X, apoptosis regulator	Homo sapiens	133-136
62740-5	1976	When a fixative mixture of methanol:acetic acid:formalin (85:5:10 by volume; MAF) is used, the concentration of nuclear solids during NYS staining remain at a physiological level of 19 per cent.	Methanol	27-35	MAF bZIP transcription factor	Homo sapiens	77-80
178873-3	1976	It has now been shown that the 2,2"-anhydro linkage in 1 and 3 can be selectively and efficiently cleaved by treatment with a mixture of pyridine and methanol giving the corresponding 3"-O-acyl derivatives of 1-beta-D-arabinofuranosylcytosine (2,4).	Methanol	150-158	inversion, Chr 17	Mus musculus	52-62
963012-2	1976	The nitrile group in these cyanomethyl thioglycosides can be converted to a methyl imidate group by treatment with sodium methoxide or HC1 in dry methanol to yield 2-imino-2-methoxyethyl 1-thioglycosides (IME-thioglycosides).	Methanol	146-154	CYCS pseudogene 39	Homo sapiens	135-138
952853-7	1976	Addition of up to 30% methanol results in a progressive decrease both in delta and rho 1/2, in agreement with the concept that hydrophobic bonding stabilizes the native structure.	Methanol	22-30	ras homolog family member A	Homo sapiens	83-90
953152-4	1976	Comparing the data for the reaction XM(+) leads to X(-) + M(2+) in methanol at 25 degrees for several M(2+) we find that the equilibrium constants increase in the order CoX(+) less than MnX(+) and span only a factor of 5 while the rate constants increase in the order NiX(+) less than CoX(+) less than MnX(+) and span a factor of more than 100.	Methanol	67-75	keratin 86	Homo sapiens	186-189
953152-4	1976	Comparing the data for the reaction XM(+) leads to X(-) + M(2+) in methanol at 25 degrees for several M(2+) we find that the equilibrium constants increase in the order CoX(+) less than MnX(+) and span only a factor of 5 while the rate constants increase in the order NiX(+) less than CoX(+) less than MnX(+) and span a factor of more than 100.	Methanol	67-75	keratin 86	Homo sapiens	302-305
1254583-5	1976	After treatment of the rhodopsin with chloroform/methanol (2/1) to remove lipids and detergents, the carbohydrate content was measured by gas-liquid chromatography, colorimetric and enzymatic analyses, paper chromatography, and electrophoresis.	Methanol	49-57	rhodopsin	Bos taurus	23-32
767170-5	1976	On the assay of biological materials, LH-RH was extracted by methanol because LH-RH was rapidly destroyed in the serum, and this breakdown could not be prevented by benzamidine or 2,3-dimercaptopropranol.	Methanol	61-69	gonadotropin releasing hormone 1	Homo sapiens	38-43
813988-11	1976	However, when 5-8 ml of trunk blood was extracted with methanol, 8-11 pg/ml of TRH was found, and the TRH levels were slightly but significantly elevated after cold exposure.	Methanol	55-63	thyrotropin releasing hormone	Rattus norvegicus	79-82
55487-4	1976	The CSF cells collected were fixed in methanol and the microautoradiographic procedure was performed.	Methanol	38-46	colony stimulating factor 2	Homo sapiens	4-7
767170-5	1976	On the assay of biological materials, LH-RH was extracted by methanol because LH-RH was rapidly destroyed in the serum, and this breakdown could not be prevented by benzamidine or 2,3-dimercaptopropranol.	Methanol	61-69	gonadotropin releasing hormone 1	Homo sapiens	78-83
9184-1	1976	A method of extraction of synthetic LHRH is studied in human urines, using porous glass (Spherosil) and methanol.	Methanol	104-112	gonadotropin releasing hormone 1	Homo sapiens	36-40
9184-5	1976	The use of methanol acidified at pH 3 increases the speed and the importance of labelled LHRH recovery.	Methanol	11-19	gonadotropin releasing hormone 1	Homo sapiens	89-93
1218995-0	1975	Proceedings: Recent studies with the methanol extraction residue fraction of tubercle bacilli (MER): efficacy of distal administration against solid tumors of experimental animals, and stimulation of cellular immunologic responsiveness in cancer patients.	Methanol	37-45	MER proto-oncogene, tyrosine kinase	Homo sapiens	95-98
240438-1	1975	H+ titration curves of hen egg-white lysozyme were obtained at 0.15 I in the presence of small amounts (less than 15%) of methanol, ethanol and n-propanol.	Methanol	122-130	lysozyme	Homo sapiens	37-45
1220689-7	1975	Studies with whole cells of Pseudomonas AM1 and a cytochrome c-deficient mutant have demonstrated that cytochrome b (redox potential 0.009V) is the first cytochrome in the electron-transport chain for oxidation of all substrates except methanol (and ethanol) whose oxidation does not involve this cytochrome.	Methanol	236-244	MEXAM1_RS12150	Methylobacterium extorquens AM1	50-62
1220689-7	1975	Studies with whole cells of Pseudomonas AM1 and a cytochrome c-deficient mutant have demonstrated that cytochrome b (redox potential 0.009V) is the first cytochrome in the electron-transport chain for oxidation of all substrates except methanol (and ethanol) whose oxidation does not involve this cytochrome.	Methanol	236-244	MEXAM1_RS00595	Methylobacterium extorquens AM1	103-115
240827-6	1975	In intact hepatic microsomes, the catalase inhibitor sodium azide slightly decreased the oxidation of methanol and ethanol, but not that of propanol and butanol, indicating a facultative role of contaminating catalase in the microsomal oxidation of lower aliphatic alcohols only.	Methanol	102-110	catalase	Rattus norvegicus	34-42
811457-5	1975	Synthetic TRH could be quantitatively extracted by methanol when added to human plasma in concentration of 25, 50 and 100 pg/ml.	Methanol	51-59	thyrotropin releasing hormone	Homo sapiens	10-13
172084-0	1975	Human liver alcohol dehydrogenase--inhibition of methanol activity by pyrazole, 4-methylpyrazole, 4-hydroxymethylpyrazole and 4-carboxypyrazole.	Methanol	49-57	aldo-keto reductase family 1 member A1	Homo sapiens	12-33
1236830-0	1975	A convenient esterification of insulin with boron trifluoride/methanol.	Methanol	62-70	insulin	Homo sapiens	31-38
1180552-0	1975	Vitamin B12 production by a methanol-utilizing bacterium.	Methanol	28-36	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	8-11
239691-5	1975	A mutant lacking cytochrome c oxidizes all substrates except methanol, ethanol and methylamine; these no longer support growth.	Methanol	61-69	MEXAM1_RS12150	Methylobacterium extorquens AM1	17-29
1171984-4	1975	From 2, [3-thienylalanine]-8-lysine-vasopressin was obtained by removing the Boc-protecting groups with trifluoroacetic acid and ethylcarbamoyl (Ec) protecting groups in refluxing liquid NH3 followed by oxidative cyclization in H2O-MeOH using ICH2CH2I.	Methanol	232-236	arginine vasopressin	Rattus norvegicus	36-47
1120154-8	1975	The specific activities for the Ss blood group antigens were increased 3-10-fold by purificantion of GP-III from the aqueous phase of chloroform methanol extracts.	Methanol	145-153	glycophorin B (MNS blood group)	Homo sapiens	32-46
167507-0	1975	Effect of precipitation with methanol on antigenic potency of TGE virus.	Methanol	29-37	transglutaminase 3	Homo sapiens	62-65
4452669-0	1974	Methanol oxidation in a reconstituted system of NADPH-cytochrome c reductase, catalase, and a factor from trypsin digested microsomes.	Methanol	0-8	catalase	Homo sapiens	78-86
1244102-3	1975	Carboxylic acid groups have been methylated with BCl3-methanol and phenolic and amine groups have been acylated to pentafluoropropionyl derivatives.	Methanol	54-62	BCL3 transcription coactivator	Homo sapiens	49-53
803278-1	1975	Acrosin, a trypsin-like proteinase, was localized in the acrosome of methanol-fixed bovine spermatoza by the indirect immunofluorescent technique.	Methanol	69-77	acrosin	Bos taurus	0-7
4462558-3	1974	Turkey liver xanthine dehydrogenase engaged in catalysing the oxidation of xanthine by dichlorophenol-indophenol was progressively inactivated by methanol.	Methanol	146-154	xanthine dehydrogenase/oxidase	Meleagris gallopavo	13-35
4988806-0	1969	Role of the intracellular distribution of hepatic catalase in the peroxidative oxidation of methanol.	Methanol	92-100	catalase	Homo sapiens	50-58
11945362-1	1970	The nucleoside was crystallized from aqueous methanol as its iodide monohydrate in space group P2(1).	Methanol	45-53	H3 histone pseudogene 16	Homo sapiens	95-100
5273889-2	1970	Oxytocin, in a dimethylsulfoxide-methanol mixture, contains a beta-turn involving the sequence -L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-.	Methanol	33-41	oxytocin/neurophysin I prepropeptide	Homo sapiens	0-8
4154098-0	1974	NADPH-dependent oxidation of methanol, ethanol, propanol and butanol by hepatic microsomes.	Methanol	29-37	2,4-dienoyl-CoA reductase 1	Homo sapiens	0-5
4721624-0	1973	The effect of methanol and dioxan on the rates of the beta-galactosidase-catalysed hydrolyses of some beta-D-galactrophyranosides: rate-limiting degalactosylation.	Methanol	14-22	galactosidase beta 1	Homo sapiens	54-72
4721624-3	1973	The effect of methanol on the beta-galactosidase-catalysed hydrolysis of some nitrophenyl beta-d-galactopyranosides has been studied under steady-state conditions.	Methanol	14-22	galactosidase beta 1	Homo sapiens	30-48
4315933-15	1970	This shows that hydroxypyruvate reductase is necessary for growth on methanol, methylamine and formate but not for growth on succinate.	Methanol	69-77	MEXAM1_RS25950	Methylobacterium extorquens AM1	16-41
14367322-0	1955	The influence of vitamin B12 on the biosynthesis of the methyl group of choline from methanol.	Methanol	85-93	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	25-28
14469361-0	1962	Comments on a recent publication by Kini and Cooper which purports to show that alcohol dehydrogenase is responsible for the physiological oxidation of methanol.	Methanol	152-160	aldo-keto reductase family 1 member A1	Homo sapiens	80-101
13410616-0	1956	[Effect of insulin on acute methyl alcohol poisoning in animals].	Methanol	28-42	insulin	Homo sapiens	11-18
4972129-0	1968	Role of the intracellular distribution of hepatic catalase in the peroxidative oxidation of methanol.	Methanol	92-100	catalase	Homo sapiens	50-58
14799638-0	1950	Combustion of C14 labeled methanol in intact rat and its isolated tissues.	Methanol	26-34	anti-Mullerian hormone receptor type 2	Rattus norvegicus	14-17
34058181-7	2021	A rapid response (34.5) for CdO-ZnO nanorices based formaldehyde gas sensor was observed as compared to other gases such as ammonia (12.3), methanol (16.5), ethanol (20), carbon monoxide (16.3) and methane (12.4), which confirm the high-selectivity towards formaldehyde gas.	Methanol	140-148	cell adhesion associated, oncogene regulated	Homo sapiens	28-31
33744543-0	2021	Stable CuO with variable valence states cooperated with active Co2+ as catalyst/co-catalyst for oxygen reduction/methanol oxidation reactions.	Methanol	113-121	complement C2	Homo sapiens	63-66
33744543-1	2021	Catalysts/co-catalysts for cathodic oxygen reduction and anodic methanol oxidation reactions (ORR/MOR) play the major roles in promoting the commercialization of direct methanol fuel cells.	Methanol	64-72	opioid receptor mu 1	Homo sapiens	98-101
33744543-1	2021	Catalysts/co-catalysts for cathodic oxygen reduction and anodic methanol oxidation reactions (ORR/MOR) play the major roles in promoting the commercialization of direct methanol fuel cells.	Methanol	169-177	opioid receptor mu 1	Homo sapiens	98-101
33741441-3	2021	AIM OF THE STUDY: To investigate the anti-inflammatory activity of methanol/dichloromethane extract (MDE) of leaves of V. zeylanica by assessing in vivo inhibition of rat paw-edema, in vitro inhibition of the production of nitric oxide (NO) and superoxide and inhibitory effect on inducible nitric oxide synthase (iNOS) gene expression.	Methanol	67-75	nitric oxide synthase 2	Rattus norvegicus	281-312
33741441-3	2021	AIM OF THE STUDY: To investigate the anti-inflammatory activity of methanol/dichloromethane extract (MDE) of leaves of V. zeylanica by assessing in vivo inhibition of rat paw-edema, in vitro inhibition of the production of nitric oxide (NO) and superoxide and inhibitory effect on inducible nitric oxide synthase (iNOS) gene expression.	Methanol	67-75	nitric oxide synthase 2	Rattus norvegicus	314-318
33714857-8	2021	The selectivity to MeOH was also improved by the cascade reaction with AOD-FALDH as no sensor output was observed from other aliphatic alcohols than MeOH in contrast to the AOD electrosensor.	Methanol	19-23	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	75-80
33714857-8	2021	The selectivity to MeOH was also improved by the cascade reaction with AOD-FALDH as no sensor output was observed from other aliphatic alcohols than MeOH in contrast to the AOD electrosensor.	Methanol	149-153	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	75-80
33876639-1	2021	A ReCl(CO)5/MeC(CH2PPh2)3 (L2) system was developed for the C-methylation reactions utilizing methanol and base, following the borrowing hydrogen strategy.	Methanol	94-102	C-C motif chemokine ligand 28	Homo sapiens	12-15
34040458-11	2021	The growth of P. aeruginosa was inhibited at a minimum concentration of both methanol and petroleum extracts (1.5625 mg/mL) when compared to the remaining bacterial strains.	Methanol	77-85	thrombopoietin	Mus musculus	120-122
34054871-6	2021	Since FH has 40 disulfide bonds, we created a P. pastoris strain containing a methanol-inducible codon-modified gene for protein-disulfide isomerase (PDI) and transformed this with codon-modified DNA encoding mFH under the same promoter.	Methanol	78-86	ferritin heavy polypeptide 1	Mus musculus	6-8
34054871-6	2021	Since FH has 40 disulfide bonds, we created a P. pastoris strain containing a methanol-inducible codon-modified gene for protein-disulfide isomerase (PDI) and transformed this with codon-modified DNA encoding mFH under the same promoter.	Methanol	78-86	ferritin heavy polypeptide 1	Mus musculus	209-212
34041327-0	2021	Data on the mechanisms of antidiarrhoeal activity of methanol leaf extract of Combretum hypopilinum Diels (Combretaceae): Involvement of opioidergic and (alpha1 and beta)-adrenergic pathways.	Methanol	53-61	brain protein 1	Mus musculus	154-169
33733601-3	2021	Due to the integration of ultralong PtPd nanowires and stable graphene support, PtPd NWs/graphene exhibited outstanding electrochemical activity toward methanol oxidation reaction (MOR) in comparison with pure Pt NWs/graphene and commercial Pt/C catalysts.	Methanol	152-160	protein tyrosine phosphatase receptor type D	Homo sapiens	80-84
33733601-4	2021	Meanwhile, PtPd NWs/graphene had a much higher current density than Pt NWs/graphene and commercial Pt/C catalysts at a constant potential for 7200s in alkaline methanol solution.	Methanol	160-168	protein tyrosine phosphatase receptor type D	Homo sapiens	11-15
33650598-5	2021	We show that water is unlikely to be important in this stage of the process, C-H bonds of C2 and C3 species can give an energetically favourable pathway and that the disproportionation of hydroxymethyl radicals to methanol and formaldehyde produces a very favourable route.	Methanol	214-222	complement C2	Homo sapiens	90-99
33733601-0	2021	Ultralong PtPd Alloyed Nanowires Anchored on Graphene for Efficient Methanol Oxidation Reaction.	Methanol	68-76	protein tyrosine phosphatase receptor type D	Homo sapiens	10-14
33853327-2	2021	Methanol or ethanol vapor reversibly and significantly changed the luminescent color of the CP between green and yellow (Deltalambdaem = 32 nm).	Methanol	0-8	ceruloplasmin	Homo sapiens	92-94
33635498-1	2021	A Schiff-base 2-((E)-(3-(prop-1-en-2-yl)phenylimino)methyl)-4-nitrophenol (Receptor 1) colorimetric probe was synthesized and its UV-visible and fluorescence spectral properties for the sensing of Cu+ 2 ions in CH3OH/H2O (60:40,v/v) solvent system was explored.	Methanol	211-216	PROP paired-like homeobox 1	Homo sapiens	25-31
33877179-5	2021	The reaction conditions will determine the pathway followed and all pathways are initiated through the initial formation of a superoxo complex, CoIII(salen)(O2 )(MeOH) (EPR: g = 2.025, A = 19 G).	Methanol	162-166	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	144-149
33929102-6	2021	In addition, the Bi-NSs based CO2RR/methanol oxidation reaction (CO2RR/MOR) electrolytic system for overall CO2 splitting was constructed, evidencing the feasibility of its practical implementation.	Methanol	36-44	opioid receptor mu 1	Homo sapiens	71-74
33784101-1	2021	A mild condition via PPh3/I2/imidazole for the deoxygenation of substituted methanol derivatives has been identified.	Methanol	76-84	caveolin 1	Homo sapiens	21-25
33918943-4	2021	The antioxidant activities of methanol extracts from A. cinnamomea cultured on KLEE (MEAC-KLEE) were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging effect, reducing power, and ferrous ion-chelating effect, and the effective concentration (EC50) values were 0.27, 0.74, and 0.37 mg mL-1, respectively.	Methanol	30-38	L1 cell adhesion molecule	Mus musculus	303-307
33600177-2	2021	In a project aimed at the valorization of this waste product, we observed that a 70% EtOH extract of the corms and a sugar-depleted MeOH fraction of the extract inhibited the TNF-alpha/IFN-gamma-induced secretion and gene expression of the chemokines IL-8, MCP-1, and RANTES in human HaCaT cells.	Methanol	132-136	tumor necrosis factor	Mus musculus	175-184
33539811-0	2021	A novel metabolic disorder in the degradation pathway of endogenous methanol due to a mutation in the gene of alcohol dehydrogenase.	Methanol	68-76	aldo-keto reductase family 1 member A1	Homo sapiens	110-131
33539811-1	2021	BACKGROUND: A small amount of methanol is produced endogenously in the human body but it is efficiently metabolized by alcohol dehydrogenase (ADH) and other enzymes, and the products eliminated without harm.	Methanol	30-38	aldo-keto reductase family 1 member A1	Homo sapiens	119-140
33539811-1	2021	BACKGROUND: A small amount of methanol is produced endogenously in the human body but it is efficiently metabolized by alcohol dehydrogenase (ADH) and other enzymes, and the products eliminated without harm.	Methanol	30-38	aldo-keto reductase family 1 member A1	Homo sapiens	142-145
33539811-12	2021	CONCLUSION: Accumulation of methanol due to mutation in ADH1C gene may result in drunkenness and ataxia, and leads to coma.	Methanol	28-36	alcohol dehydrogenase 1C (class I), gamma polypeptide	Homo sapiens	56-61
33359856-0	2021	Mechanisms of Antidiarrhoeal Activity of Methanol Leaf Extract of Combretum hypopilinum Diels (Combretaceae): Involvement of Opioidergic and (alpha1 and beta)-Adrenergic Pathways.	Methanol	41-49	brain protein 1	Mus musculus	142-157
33359856-12	2021	CONCLUSION: The results obtained in this study suggest the probable involvement of opioidergic and (alpha1 and beta)-adrenergic systems in the antidiarrhoeal activity of the methanol leaf extract of Combretum hypopilinum.	Methanol	174-182	brain protein 1	Mus musculus	100-115
33360534-6	2021	In this manner, the methanol conversion and products selectivity of prepared materials were carried out in MTP reaction at 460  C and atmospheric pressure.	Methanol	20-28	metallothionein 1B	Homo sapiens	107-110
33600177-2	2021	In a project aimed at the valorization of this waste product, we observed that a 70% EtOH extract of the corms and a sugar-depleted MeOH fraction of the extract inhibited the TNF-alpha/IFN-gamma-induced secretion and gene expression of the chemokines IL-8, MCP-1, and RANTES in human HaCaT cells.	Methanol	132-136	interferon gamma	Mus musculus	185-194
33600177-2	2021	In a project aimed at the valorization of this waste product, we observed that a 70% EtOH extract of the corms and a sugar-depleted MeOH fraction of the extract inhibited the TNF-alpha/IFN-gamma-induced secretion and gene expression of the chemokines IL-8, MCP-1, and RANTES in human HaCaT cells.	Methanol	132-136	chemokine (C-X-C motif) ligand 15	Mus musculus	251-255
33600177-2	2021	In a project aimed at the valorization of this waste product, we observed that a 70% EtOH extract of the corms and a sugar-depleted MeOH fraction of the extract inhibited the TNF-alpha/IFN-gamma-induced secretion and gene expression of the chemokines IL-8, MCP-1, and RANTES in human HaCaT cells.	Methanol	132-136	chemokine (C-C motif) ligand 5	Mus musculus	268-274
33599728-0	2021	Beyond alcohol oxidase: The methylotrophic yeast Komagataella phaffii utilizes methanol also with its native alcohol dehydrogenase Adh2.	Methanol	79-87	alcohol dehydrogenase ADH2	Saccharomyces cerevisiae S288C	131-135
33599728-8	2021	Overexpression of the ADH2 gene in K. phaffii Mut- increased both the specific methanol uptake rate and recombinant protein production, even though the strain was still unable to grow.	Methanol	79-87	alcohol dehydrogenase ADH2	Saccharomyces cerevisiae S288C	22-26
33606934-3	2021	It is widely accepted that the protonation in the gas phase takes place primarily on the carbonyl oxygen atom when the sample is sprayed in methanol and on the nitrogen atom when acetonitrile is used as the spray solvent.	Methanol	140-148	gastrin	Homo sapiens	50-53
33551051-7	2021	The computational inversion of the PLS2 prediction model looking for the Pareto front of these six responses provides a set of experimental conditions to conduct the chromatographic determination, specifically 22% of water, mixed with 58% methanol and 20% of acetonitrile, keeping the flow rate at 0.66 mL min-1.	Methanol	239-247	lymphocyte cytosolic protein 1	Homo sapiens	35-39
33309216-0	2021	A passive direct methanol fuel cell as transducer of an electrochemical sensor, applied to the detection of carcinoembryonic antigen.	Methanol	17-25	CEA cell adhesion molecule 3	Homo sapiens	108-132
33309216-1	2021	This work describes an electrochemical sensor with a biomimetic plastic antibody film for carcinoembryonic antigen (CEA, an important biomarker in colorectal cancer), integrated in the electrical circuit of a direct methanol fuel cell (DMFC), working in passive mode and used herein as power supply and signal transducer.	Methanol	216-224	CEA cell adhesion molecule 3	Homo sapiens	90-114
33309216-1	2021	This work describes an electrochemical sensor with a biomimetic plastic antibody film for carcinoembryonic antigen (CEA, an important biomarker in colorectal cancer), integrated in the electrical circuit of a direct methanol fuel cell (DMFC), working in passive mode and used herein as power supply and signal transducer.	Methanol	216-224	CEA cell adhesion molecule 3	Homo sapiens	116-119
32762574-1	2021	CONTEXT: Investigate whether 123I-ioflupane SPECT (DaT SPECT) has the potential as a marker of basal ganglia damage in acute methanol poisoning.	Methanol	125-133	solute carrier family 6 member 3	Homo sapiens	51-54
32762574-13	2021	CONCLUSION: DaT SPECT demonstrates significant potential for the diagnosis of methanol-induced basal ganglia damage.	Methanol	78-86	solute carrier family 6 member 3	Homo sapiens	12-15
33738074-2	2021	The asymmetric structural unit of P-FAH-Cu-phen was composed of two independent complex units [CuL(phen)(CH3OH)] and [CuL(phen)]:Cu12+ center with six coordination mode and Cu22+ center with five coordination mode.	Methanol	105-110	fumarylacetoacetate hydrolase	Homo sapiens	36-39
33486447-4	2021	We adjusted the EURLMB extraction method by either using an acidified methanol extraction or pre-cooking shellfish homogenates at 70  C for 20 min before EURLMB extraction.	Methanol	70-78	chromosome 21 open reading frame 91	Homo sapiens	16-22
33567826-1	2021	Phytochemical investigation of the methanol extract of the aerial parts of Salvia plebeia aided by a proprotein convertase subtilisin/kexin type 9 (PCSK9) mRNA expression screening assay in HepG2 cells led to the identification of 19 compounds including one new norsesquiterpene (1), six new eudesmane sesquiterpenoids (2-5, 8, and 11), and 12 known compounds.	Methanol	35-43	proprotein convertase subtilisin/kexin type 9	Homo sapiens	148-153
33502190-8	2021	We also examined the effect of replacing water with methanol on the ease of the SN2 reaction, finding that the replacement resulted in a higher activation barrier for the generation of BrO-.	Methanol	52-60	solute carrier family 38 member 5	Homo sapiens	80-83
33679166-3	2021	In addition, the thermodynamic limitations of methanol and DME formation from CO2 was investigated at a temperature range of 100-400  C. Cu-Ho-Ga/g-Al2O3 catalyst shows the highest formation rate of methanol (90.3 micromolCH3OH/gcat/h ) and DME (13.2 micromolDME/gcat/h) as well as the highest selectivity towards methanol and DME (39.9 %) at 210  C using a CO2:H2 1:9 feed ratio.	Methanol	46-54	ornithine aminotransferase	Homo sapiens	140-147
33679166-3	2021	In addition, the thermodynamic limitations of methanol and DME formation from CO2 was investigated at a temperature range of 100-400  C. Cu-Ho-Ga/g-Al2O3 catalyst shows the highest formation rate of methanol (90.3 micromolCH3OH/gcat/h ) and DME (13.2 micromolDME/gcat/h) as well as the highest selectivity towards methanol and DME (39.9 %) at 210  C using a CO2:H2 1:9 feed ratio.	Methanol	199-207	ornithine aminotransferase	Homo sapiens	140-147
33679166-3	2021	In addition, the thermodynamic limitations of methanol and DME formation from CO2 was investigated at a temperature range of 100-400  C. Cu-Ho-Ga/g-Al2O3 catalyst shows the highest formation rate of methanol (90.3 micromolCH3OH/gcat/h ) and DME (13.2 micromolDME/gcat/h) as well as the highest selectivity towards methanol and DME (39.9 %) at 210  C using a CO2:H2 1:9 feed ratio.	Methanol	199-207	ornithine aminotransferase	Homo sapiens	140-147
33528487-3	2021	Benefiting from the electronic and structural effects, Au@mPd NFs show excellent electrocatalytic activity and stability for methanol oxidation reaction in alkaline electrolytes.	Methanol	125-133	mevalonate (diphospho) decarboxylase	Mus musculus	58-61
33572333-6	2021	The fluorescence titration of 2b (10 mM) with Cd2+ showed that the limit of detection (LOD) of the Cd2+-selective 2b was 158 nM in PBS (phosphate-buffered saline) (10 mM, pH 7.2) containing 50% MeOH.	Methanol	194-198	CD2 molecule	Homo sapiens	99-102
32488689-5	2021	Longstanding fixation in Cytolyt, methanol-based fixative for cytology samples, but also decalcification using a mix of formic- and hydrochloracid resulted in decreased DLL3 staining.	Methanol	34-42	LOC105375808	Homo sapiens	169-173
33122138-7	2021	The results showed that the optimized conditions for ULBP1xCD19-scFv expression were 1% methanol induction for 96 h with 15% broth content.	Methanol	88-96	immunglobulin heavy chain variable region	Homo sapiens	64-68
33458957-4	2021	Here, a noble metal-free catalyst, Ni1- x Fex Se2 nanorods, with a high potential for an efficient and selective methanol conversion to formate is demonstrated.	Methanol	113-121	fucosyltransferase 2	Homo sapiens	46-49
33439639-2	2021	Although homogeneous CO2 hydrogenation in water catalyzed by amide-based iridium catalysts provided only a negligible amount of methanol, the combination of a multinuclear catalyst and gas-solid phase reaction conditions led to the effective production of methanol from CO2.	Methanol	128-136	gastrin	Homo sapiens	185-188
33439639-0	2021	Catalytic Hydrogenation of CO2 to Methanol Using Multinuclear Iridium Complexes in a Gas-Solid Phase Reaction.	Methanol	34-42	gastrin	Homo sapiens	85-88
33439639-2	2021	Although homogeneous CO2 hydrogenation in water catalyzed by amide-based iridium catalysts provided only a negligible amount of methanol, the combination of a multinuclear catalyst and gas-solid phase reaction conditions led to the effective production of methanol from CO2.	Methanol	256-264	gastrin	Homo sapiens	185-188
33439639-1	2021	We report a novel approach toward the catalytic hydrogenation of CO2 to methanol performed in the gas-solid phase using multinuclear iridium complexes at low temperature (30-80  C).	Methanol	72-80	gastrin	Homo sapiens	98-101
33439639-4	2021	Conveniently, methanol obtained from the gas phase could be easily isolated from the catalyst without contamination with CO, CH4, or formic acid (FA).	Methanol	14-22	gastrin	Homo sapiens	41-44
33356211-0	2021	Mechanism of Methanol Decomposition over Single-Site Pt1/CeO2 Catalyst: A DRIFTS Study.	Methanol	13-21	zinc finger protein 77	Homo sapiens	53-56
33356211-3	2021	Herein, the reaction mechanism of methanol decomposition over Pt1/CeO2 was carefully investigated using in situ DRIFTS, and a reaction pathway was proposed.	Methanol	34-42	zinc finger protein 77	Homo sapiens	62-65
33356211-5	2021	The ease of methanol dissociative adsorption on nanoceria support and the tailored electronic property of Pt1 via the metal-support interaction are believed to be strongly correlated with the high activity of Pt1/CeO2.	Methanol	12-20	zinc finger protein 77	Homo sapiens	209-212
33518676-7	2021	Consistent with these observations, P. crocatum methanol extract and compound 1 remarkably decreased beta-hexosaminidase release from RBL-2H3 cells stimulated with 2,4-dinitrophenylated bovine serum albumin (DNP-BSA)-specific immunoglobulin E (IgE) antibodies.	Methanol	48-56	albumin	Rattus norvegicus	193-206
33372797-2	2021	Herein, the novel V-doped Ni3S2/NiS heterostructure nanorod arrays grown on nickel foam (VNS/NF-WM) are synthesized via a facile methanol-assisted hydrothermal method.	Methanol	129-137	neurofascin	Homo sapiens	93-95
33372797-3	2021	We demonstrate that the morphology, phase composition, and crystallinity of VNS/NF are well modulated by tuning the ratios of water/methanol solvent.	Methanol	132-140	neurofascin	Homo sapiens	80-82
33372797-4	2021	The optimized VNS/NF-WM-heterostructured nanorod (volume ratio of water/methanol is 3:1) exhibits superior HER electrocatalytic activity with low overpotentials of 85 and 218 mV to yield current density values of 10 and 100 mA cm-2, respectively, meanwhile sustaining an excellent stability with almost an unchanged current density of 10 mA cm-2 for 60 h. Our work offers fresh insights into the rational design of highly active and stable earth-abundant-heterostructured electrocatalysts for the hydrogen fuel production.	Methanol	72-80	neurofascin	Homo sapiens	18-20
33429942-9	2021	In terms of the biological properties, the M. koenigii methanol extract was found to display the greatest amount of antioxidant activity (DPPH; IC50 95.54 microg/mL, ABTS value 118.12 mg GAE/g extract, FRAP value 48.15 mg GAE/g extract), and also revealed the highest alpha-glucosidase and antihypertensive inhibitory activities with percent inhibition values of 84.55 and 84.95.	Methanol	55-63	mechanistic target of rapamycin kinase	Homo sapiens	202-206
33429942-9	2021	In terms of the biological properties, the M. koenigii methanol extract was found to display the greatest amount of antioxidant activity (DPPH; IC50 95.54 microg/mL, ABTS value 118.12 mg GAE/g extract, FRAP value 48.15 mg GAE/g extract), and also revealed the highest alpha-glucosidase and antihypertensive inhibitory activities with percent inhibition values of 84.55 and 84.95.	Methanol	55-63	sucrase-isomaltase	Homo sapiens	268-285
32856909-3	2021	Multiple regression analysis suggests that for field-free cVSSI, ion intensity is mostly associated with the log of the base dissociation constant (pKb) and proton affinity (PA) for both aqueous and methanol solutions.	Methanol	199-207	AKT serine/threonine kinase 1	Homo sapiens	148-151
32856909-6	2021	For ESI, pKb is the dominant factor associated with ion signal levels from methanol and aqueous solutions.	Methanol	75-83	AKT serine/threonine kinase 1	Homo sapiens	9-12
33306387-4	2020	Among them, acetone fraction (rich in glycolipid) and MeOH fraction (rich in phospholipid) markedly inhibited beta-hexosaminidase release from RBL-2H3 cells.	Methanol	54-58	O-GlcNAcase	Rattus norvegicus	110-129
31393258-12	2021	Thus, MeOH extract of Salvia officinalis able to inhibit 50% of the activity of aging related enzymes Col-I, Ela-I and Hya-I.	Methanol	6-10	lysine demethylase 5D	Homo sapiens	119-122
32679417-4	2020	In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status.	Methanol	42-50	glutamic pyruvic transaminase, soluble	Mus musculus	131-155
33263395-8	2020	Pulsed gradient spin echo diffusion ordered 1H NMR spectroscopy and electrospray ionization mass spectrometry confirmed that the structure of Ln-1 remains intact in methanol solutions while mass spectrometry suggests that four OH- bridges are exchanged with CH3O-/CD3O-.	Methanol	165-173	phytanoyl-CoA 2-hydroxylase	Homo sapiens	142-146
33263395-14	2020	Values obtained for Yb-1, that is, 0.78(4) % in CH3OH and 8.4(1)% in CD3OD, are among the highest ones reported today for Yb3+ complexes formed with nondeuterated and nonhalogenated ligands.	Methanol	48-53	Y-box binding protein 1	Homo sapiens	20-24
32679417-4	2020	In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status.	Methanol	42-50	glutamic pyruvic transaminase, soluble	Mus musculus	157-160
32679417-4	2020	In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status.	Methanol	42-50	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	163-189
32679417-4	2020	In alloxan-induced diabetic mice, the AFS methanol extract (AFSE) rich in caffeoylquinic acids and flavones reduced blood glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, creatinine, and improved liver, and renal antioxidative status.	Methanol	42-50	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	191-194
33161359-9	2020	System maps for XBridge Shield RP18 for 20-70% (v/v) methanol-water and Synergi Hydro-RP and 50% (v/v) methanol-water at temperatures from 25-65  C together with a correlation diagram for XBridge Shield RP18 and SunFire C18 are presented as representative applications of the reduced calibration compounds for column selectivity evaluation.	Methanol	53-61	pre-mRNA processing factor 3	Homo sapiens	31-35
33297427-0	2020	Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.	Methanol	19-27	mitogen-activated protein kinase kinase kinase 7	Mus musculus	82-86
33297427-0	2020	Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.	Methanol	19-27	jun proto-oncogene	Mus musculus	94-98
33137228-2	2020	To address this issue, herein, we report a Perylenediimide-Peptide conjugate, PDI-1 , for detection of PA in methanol.	Methanol	109-117	peptidyl arginine deiminase 1	Homo sapiens	78-83
33297548-2	2020	This paper reports the effect of different zeolitic frameworks (such as: BEA, EUO, FER, MFI, MOR, MTW, TON) on methanol conversion, DME selectivity and catalyst deactivation.	Methanol	111-119	opioid receptor mu 1	Homo sapiens	93-96
33161359-9	2020	System maps for XBridge Shield RP18 for 20-70% (v/v) methanol-water and Synergi Hydro-RP and 50% (v/v) methanol-water at temperatures from 25-65  C together with a correlation diagram for XBridge Shield RP18 and SunFire C18 are presented as representative applications of the reduced calibration compounds for column selectivity evaluation.	Methanol	103-111	pre-mRNA processing factor 3	Homo sapiens	31-35
32737906-9	2020	The methanolic extract of R.canina fruits has a total antioxidant capacity of 82.69+-1.18 mug EAA/mg of methanol extract and the IC50 of the methods used is in the following increasing order: FRAP assay (61.88 mug/ml), then hydroxyl radical scavenging assay (67.45 mug/ml) and then DPPH radical-scavenging activity (129.81 mug/ml).	Methanol	4-12	mechanistic target of rapamycin kinase	Homo sapiens	192-196
33171022-7	2020	Regarding the antioxidant activity, methanol extracts of Tizona cultivar mature leaves displayed important antiradical properties using DPPH, ABTS, and phosphomolybdenum assays (IC50 0.1, 0.2 and 0.01 mg mL-1 , respectively).	Methanol	36-44	L1 cell adhesion molecule	Mus musculus	204-208
33164620-3	2020	OBJECTIVE: To assess the anti-inflammatory effect of the methanol extract of Schumanniophyton magnificum (MESM) leaves through the inhibition of PLA2 and investigate the compounds responsible for the effect.	Methanol	57-65	phospholipase A2 group IB	Homo sapiens	145-149
33153260-0	2020	Breakdown of the Stokes-Einstein Relation in Supercooled Water/Methanol Binary Mixtures: Explanation Using the Translational Jump-Diffusion Approach.	Methanol	63-71	squalene epoxidase	Homo sapiens	17-32
33324817-4	2020	The yield of CS2/NMP extracts from lignite was quite higher than that of methanol extracts.	Methanol	73-81	chorionic somatomammotropin hormone 2	Homo sapiens	13-16
33324817-5	2020	Furthermore, the yield of methanol-soluble portions from CS2/NMP extracts was far more than that of methanol extracts from lignite.	Methanol	26-34	chorionic somatomammotropin hormone 2	Homo sapiens	57-60
33153260-1	2020	A recent experiment has directly checked the validity of the Stokes-Einstein (SE) relation for pure water, pure methanol, and their binary mixtures of three different compositions at different temperatures.	Methanol	112-120	squalene epoxidase	Homo sapiens	61-76
33153260-1	2020	A recent experiment has directly checked the validity of the Stokes-Einstein (SE) relation for pure water, pure methanol, and their binary mixtures of three different compositions at different temperatures.	Methanol	112-120	squalene epoxidase	Homo sapiens	78-80
33153260-5	2020	We have used the same TJD approach for explaining the SE breakdown for the methanol/water binary mixtures of compositions studied in the experiment over a wide range of temperatures between 220 K and 300 K. We have understood that the jump-diffusion is the key responsible factor for the SE breakdown.	Methanol	75-83	squalene epoxidase	Homo sapiens	54-56
33153260-5	2020	We have used the same TJD approach for explaining the SE breakdown for the methanol/water binary mixtures of compositions studied in the experiment over a wide range of temperatures between 220 K and 300 K. We have understood that the jump-diffusion is the key responsible factor for the SE breakdown.	Methanol	75-83	squalene epoxidase	Homo sapiens	288-290
33153260-7	2020	This study, therefore, provides molecular insight into the SE breakdown for the supercooled water/methanol binary mixture, as found in the experiment.	Methanol	98-106	squalene epoxidase	Homo sapiens	59-61
33190551-1	2022	Echeveria subrigida is native to Mexico and its methanol extract (ME) shows relevant biological activities for human health, including the alpha-glucosidase inhibitory (alphaGI) activity that suggests its antidiabetic potential.	Methanol	48-56	sucrase-isomaltase	Homo sapiens	139-156
31811672-0	2020	Glucose-methanol based fed batch fermentation for the production of recombinant human interferon gamma (rhIFN-gamma) and evaluation of its antitumor potential.	Methanol	0-16	interferon gamma	Homo sapiens	86-115
33198146-10	2020	Furthermore, the methanol extract reversed P-glycoprotein or multidrug resistance-associated protein in Caco-2 cells.	Methanol	17-25	ATP binding cassette subfamily C member 3	Homo sapiens	61-100
33006897-4	2020	Notably, slight size adjustment of the Cp*Rh units was found to affect the stability of the figure-eight knots in methanol.	Methanol	114-122	ceruloplasmin	Homo sapiens	39-41
32946233-2	2020	In this study, we use quantum chemistry and Born-Oppenheimer molecular dynamics (BOMD) simulations to investigate the reaction between methanol/ethanol and Criegee intermediates (anti- or syn-CH3CHOO) in the gas phase and at the air-water interface.	Methanol	135-143	synemin	Homo sapiens	188-191
33312661-10	2020	The used SNW-1/Mt composite could be regenerated by salty methanol.	Methanol	58-66	SNW domain containing 1	Homo sapiens	9-17
32760982-11	2020	For C18 (aqueous) UHPLC-MS urine analysis, 50 : 50 methanol : water had high reproducibility and yield.	Methanol	51-59	Bardet-Biedl syndrome 9	Homo sapiens	4-7
33082348-4	2020	Treatment of D with MeOH affords two isomeric dimers, MD1 and MD2, both of which incorporate a methoxy moiety and exist in cis orientations with respect to the tethering linkage.	Methanol	20-24	MAFD1	Homo sapiens	54-57
33082348-4	2020	Treatment of D with MeOH affords two isomeric dimers, MD1 and MD2, both of which incorporate a methoxy moiety and exist in cis orientations with respect to the tethering linkage.	Methanol	20-24	lymphocyte antigen 96	Homo sapiens	62-65
33002361-5	2020	Moreover, a coordination-induced spin state switch (CISSS) to low spin is observed by using methanol as solvent, triggered through a rearrangement of the coordination sphere.	Methanol	92-100	spindlin 1	Homo sapiens	33-37
33002361-5	2020	Moreover, a coordination-induced spin state switch (CISSS) to low spin is observed by using methanol as solvent, triggered through a rearrangement of the coordination sphere.	Methanol	92-100	spindlin 1	Homo sapiens	66-70
32504902-1	2020	As the efficient approaches for obtaining clean H2 energy, methanol oxidation (MOR) and water over slitting reactions have been increasingly essential.	Methanol	59-67	opioid receptor mu 1	Homo sapiens	79-82
32790340-4	2020	It was found out that methanol played a paramount role in obtaining the Cr3+-doped ZnGa2O4 nanoparticles.	Methanol	22-30	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	72-75
32996938-0	2020	Competition between the hydrogen bond and the halogen bond in a [CH3OH-CCl4] complex: a matrix isolation IR spectroscopy and computational study.	Methanol	65-70	C-C motif chemokine ligand 4	Homo sapiens	71-75
32996938-1	2020	Methanol (CH3OH) is the simplest alcohol and carbon tetrachloride (CCl4) is widely used as a solvent in the chemical industry.	Methanol	0-8	C-C motif chemokine ligand 4	Homo sapiens	67-71
32996938-4	2020	The specific interaction between CH3OH and CCl4 is not yet investigated experimentally.	Methanol	33-38	C-C motif chemokine ligand 4	Homo sapiens	43-47
32996938-5	2020	The interaction between CH3OH and CCl4 at the molecular level can be twofold: hydrogen bond (O-HCl) and halogen bond (C-ClO) interaction.	Methanol	24-29	C-C motif chemokine ligand 4	Homo sapiens	34-38
32996938-7	2020	Herein, the 1 : 1 complex of [CH3OH-CCl4] has been characterised using matrix-isolation infrared spectroscopy and electronic structure calculations to investigate the competition between hydrogen bonded and halogen bonded complexes.	Methanol	30-35	C-C motif chemokine ligand 4	Homo sapiens	36-40
32996938-10	2020	This investigation helps to understand the specific interactions in the [CH3OH-CCl4] mixture and also the possibilities of formation of halogen bonded atmospheric complexes that may influence the atmospheric chemical activities, and enhance aerosol formation and deposition of CCl4.	Methanol	73-78	C-C motif chemokine ligand 4	Homo sapiens	79-83
32996938-10	2020	This investigation helps to understand the specific interactions in the [CH3OH-CCl4] mixture and also the possibilities of formation of halogen bonded atmospheric complexes that may influence the atmospheric chemical activities, and enhance aerosol formation and deposition of CCl4.	Methanol	73-78	C-C motif chemokine ligand 4	Homo sapiens	277-281
32852952-4	2020	Gas-phase ion-molecule reactions of trimethoxymethylsilane (TMMS) were used to identify the protonation sites of 4-aminobenzoic acid ionized using APCI with methanol or acetonitrile-water as the solvent.	Methanol	157-165	gastrin	Homo sapiens	0-3
32852952-6	2020	This finding was rationalized based on a previous finding that when the O-protomer is surrounded by more than eight methanol molecules in the gas phase, it starts behaving as if it were in an aqueous solution and converts to the N-protomer.	Methanol	116-124	gastrin	Homo sapiens	142-145
33088947-1	2020	This study investigated predictions of reaction mechanisms and reaction rate law model covering effect of plasma role on the heterogeneous catalytic reaction of triglyceride and methanol to produce biodiesel (fatty acid methyl ester - FAME or fatty acid alkyl ester - FAAE) over a continuous flow hybrid catalytic-plasma reactor.	Methanol	178-186	benign adult familial myoclonic epilepsy 1	Homo sapiens	235-239
32819704-7	2020	Compared with the engine running in pure diesel mode, when the engine ran in diesel/methanol dual fuel mode, the combustion phase was advanced, and the combustion duration became shorter.	Methanol	84-92	RAN, member RAS oncogene family	Homo sapiens	70-73
32966304-4	2020	Moreover, the methanol extracts showed the best inhibitory activity against cholinesterase and HepG2 cancer cells.	Methanol	14-22	butyrylcholinesterase	Homo sapiens	76-90
32862645-4	2020	Sensing Tb2 on different organic solvents under the same conditions showed that it exhibited excellent selective photoresponse to methanol (CH3OH).	Methanol	130-138	receptor accessory protein 5	Homo sapiens	8-11
33122979-5	2020	Cell death ELISA, TUNEL assay, and the cleavage of poly ADP-ribose polymerase (PARP) uncovered that the cytotoxic effects of dichloromethane and methanol extracts were attributed to apoptosis in cancerous cells.	Methanol	145-153	poly(ADP-ribose) polymerase 1	Homo sapiens	51-77
33122979-5	2020	Cell death ELISA, TUNEL assay, and the cleavage of poly ADP-ribose polymerase (PARP) uncovered that the cytotoxic effects of dichloromethane and methanol extracts were attributed to apoptosis in cancerous cells.	Methanol	145-153	poly(ADP-ribose) polymerase 1	Homo sapiens	79-83
32983252-2	2020	Methods: In this study, the neuroprotective effect of a methanol extract of A. gigas root (RAGE) was investigated in a mouse stroke model induced by a 90 min transient middle cerebral artery occlusion (tMCAO).	Methanol	56-64	MOK protein kinase	Mus musculus	91-95
32862645-4	2020	Sensing Tb2 on different organic solvents under the same conditions showed that it exhibited excellent selective photoresponse to methanol (CH3OH).	Methanol	140-145	receptor accessory protein 5	Homo sapiens	8-11
32862645-5	2020	Even under EtOH conditions, Tb2 could selectively respond to small amounts of CH3OH.	Methanol	78-83	receptor accessory protein 5	Homo sapiens	28-31
32961653-4	2020	Subsequent reaction of HL1 and HL2 with CuCl2 2H2O in 1:1 molar ratio in methanol produced the complexes [CuII(HL1)Cl2] H2O (1 H2O) and [CuII(HL2)Cl2] (2).	Methanol	73-81	asialoglycoprotein receptor 1	Homo sapiens	23-26
32967253-1	2020	Most of the current commercial production of glacial acetic acid (GAA) is by petrochemical routes, primarily methanol carbonylation.	Methanol	109-117	alpha glucosidase	Homo sapiens	66-69
32961653-4	2020	Subsequent reaction of HL1 and HL2 with CuCl2 2H2O in 1:1 molar ratio in methanol produced the complexes [CuII(HL1)Cl2] H2O (1 H2O) and [CuII(HL2)Cl2] (2).	Methanol	73-81	intelectin 2	Homo sapiens	31-34
32961653-4	2020	Subsequent reaction of HL1 and HL2 with CuCl2 2H2O in 1:1 molar ratio in methanol produced the complexes [CuII(HL1)Cl2] H2O (1 H2O) and [CuII(HL2)Cl2] (2).	Methanol	73-81	asialoglycoprotein receptor 1	Homo sapiens	111-114
32961653-4	2020	Subsequent reaction of HL1 and HL2 with CuCl2 2H2O in 1:1 molar ratio in methanol produced the complexes [CuII(HL1)Cl2] H2O (1 H2O) and [CuII(HL2)Cl2] (2).	Methanol	73-81	intelectin 2	Homo sapiens	142-145
32948764-3	2020	The controlled installation of N-CH3, -CDH2, -CD2H, -CD3, and -13CH3 groups into pharmaceutical amines thus has been demonstrated by tuning isotopic water and methanol.	Methanol	159-167	cardiomyopathy, dilated 1F (autosomal dominant)	Homo sapiens	46-68
32458500-3	2020	Excess CO 2 and limited H 2 in the feedstock gas mixture is not favourable for the CO 2 hydrogenation to methanol reaction, which causes low activity and poor methanol selectivity.	Methanol	159-167	relaxin 2	Homo sapiens	24-27
32458500-5	2020	The Rh-In catalyst can effectively catalyse methanol synthesis but inhibit reverse water-gas shift reaction under H 2 -deficient gas flow and shows the best competitive methanol productivity under industrially applicable conditions in comparison with the literature reported values.	Methanol	44-52	relaxin 2	Homo sapiens	114-117
32458500-5	2020	The Rh-In catalyst can effectively catalyse methanol synthesis but inhibit reverse water-gas shift reaction under H 2 -deficient gas flow and shows the best competitive methanol productivity under industrially applicable conditions in comparison with the literature reported values.	Methanol	169-177	relaxin 2	Homo sapiens	114-117
32458500-6	2020	This work demonstrates a strong potential of Rh-In bimetallic composition, from which a convenient methanol synthesis based on flexible feedstock compositions (e.g. H 2 /CO 2 from biomass derivatives) with lower energy cost can be established.	Methanol	99-107	relaxin 2	Homo sapiens	165-168
32566991-4	2020	Our previous studies suggested that the expression of SUT2 could be induced by methanol but is repressed by glycerol, which indicates that SUT2 may be involved in methanol metabolism through an unknown mechanism.	Methanol	79-87	Sut2p	Saccharomyces cerevisiae S288C	54-58
32899643-6	2020	Steroidal pyrazoles, which were produced as C-17 acetates due to acetylation of C-17 OH during the primary Friedel-Crafts reaction, underwent deacetylation in alkaline methanol to furnish 2-heterocyclic estradiol derivatives.	Methanol	168-176	cytokine like 1	Homo sapiens	44-48
32899643-6	2020	Steroidal pyrazoles, which were produced as C-17 acetates due to acetylation of C-17 OH during the primary Friedel-Crafts reaction, underwent deacetylation in alkaline methanol to furnish 2-heterocyclic estradiol derivatives.	Methanol	168-176	cytokine like 1	Homo sapiens	80-84
32787258-1	2020	A photochemically crushable and regenerative metal-organic framework (DTEMOF) was developed by complexation of photochromic ligand PyDTEopen and 5-nitroisophthalate (nip2-) with Cd2+ in DMF/MeOH.	Methanol	190-194	BCL2 interacting protein 2	Homo sapiens	166-170
32566991-4	2020	Our previous studies suggested that the expression of SUT2 could be induced by methanol but is repressed by glycerol, which indicates that SUT2 may be involved in methanol metabolism through an unknown mechanism.	Methanol	79-87	Sut2p	Saccharomyces cerevisiae S288C	139-143
32566991-4	2020	Our previous studies suggested that the expression of SUT2 could be induced by methanol but is repressed by glycerol, which indicates that SUT2 may be involved in methanol metabolism through an unknown mechanism.	Methanol	163-171	Sut2p	Saccharomyces cerevisiae S288C	54-58
32566991-4	2020	Our previous studies suggested that the expression of SUT2 could be induced by methanol but is repressed by glycerol, which indicates that SUT2 may be involved in methanol metabolism through an unknown mechanism.	Methanol	163-171	Sut2p	Saccharomyces cerevisiae S288C	139-143
32566991-7	2020	Furthermore, via truncation of the putative SUT2 promoter at diverse loci, the - 973 base pair (bp) to - 547 bp region to the ATG was shown to be the core element of the inducible promoter PSUT2, which strongly responds to the methanol signal.	Methanol	227-235	Sut2p	Saccharomyces cerevisiae S288C	44-48
32566991-11	2020	SUT2 may play roles in methanol metabolism by participating in sterol biosynthesis.	Methanol	23-31	Sut2p	Saccharomyces cerevisiae S288C	0-4
32787258-1	2020	A photochemically crushable and regenerative metal-organic framework (DTEMOF) was developed by complexation of photochromic ligand PyDTEopen and 5-nitroisophthalate (nip2-) with Cd2+ in DMF/MeOH.	Methanol	190-194	CD2 molecule	Homo sapiens	178-181
32644079-0	2020	Shape-controlled synthesis of planar PtPb nanoplates for highly efficient methanol electro-oxidation reaction.	Methanol	74-82	protein tyrosine phosphatase receptor type B	Homo sapiens	37-41
32654478-3	2020	By virtue of compositional and structural advantages, the optimized Ni1Co2Px (NiCoP/CoP/CoP2) nanoparticles shows very high mass activity (436.9 mA mg-1) and area-specific activity (155 mA cm-2), as well as remarkable durability toward methanol electrooxidation reaction (MOR) in alkaline solution.	Methanol	236-244	caspase recruitment domain family member 16	Homo sapiens	80-83
32687376-1	2020	The methyl-2,2-dicyanoacetate anion is synthesised in an electrospray ionisation source through a gas-phase reaction involving tetracyanoethylene and methanol.	Methanol	150-158	gastrin	Homo sapiens	98-101
32508086-2	2020	Bovine serum albumin (BSA) was selected to extract PFASs from aqueous samples, which were then desorbed using methanol.	Methanol	110-118	albumin	Homo sapiens	7-20
32108485-0	2020	Solution Structure, Electronic Energy Levels, and Photophysical Properties of [Eu(MeOH)n-2m(NO3)m]3-m+ Complexes.	Methanol	82-86	NBL1, DAN family BMP antagonist	Homo sapiens	92-95
32108485-5	2020	By a combination of direct and indirect methods to probe the structure, it was found that four distinct species from Eu(MeOH)93+ to [Eu(MeOH)3(NO3)3] are present in solutions containing from 0 to 2 M NO3- ions.	Methanol	136-140	NBL1, DAN family BMP antagonist	Homo sapiens	143-146
32108485-5	2020	By a combination of direct and indirect methods to probe the structure, it was found that four distinct species from Eu(MeOH)93+ to [Eu(MeOH)3(NO3)3] are present in solutions containing from 0 to 2 M NO3- ions.	Methanol	136-140	NBL1, DAN family BMP antagonist	Homo sapiens	200-203
33659349-5	2020	We found that using methanol for fixing allows the best preservation of claudin-2 both at the membrane and in cytoplasmic vesicles.	Methanol	20-28	claudin 2	Homo sapiens	72-81
32558829-1	2020	An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(eta2-1,5-cyclooctadiene)2 as the catalyst.	Methanol	172-176	DNA polymerase iota	Homo sapiens	240-244
32432600-3	2020	The ligand H2L acts as a dual sensor for CdII and PbII in methanol/HEPES buffer (5 mM, pH 7.3; 1 : 9 v/v) at room temperature with well-separated excitation and emission wavelengths.	Methanol	58-66	submaxillary gland androgen regulated protein 3B	Homo sapiens	50-54
32675173-6	2020	C-peptide was extracted by incubating the samples with methanol and measuring the extract with an immunoassay.	Methanol	55-63	insulin	Homo sapiens	0-9
32733856-2	2020	As a case study, we have chosen the CPL spectrum of camphor in methanol solution, which shows a well-defined bisignate shape.	Methanol	63-71	hephaestin	Homo sapiens	36-39
32520028-1	2020	The cationic acetate ruthenium complex [Ru(eta1-OAc)(CO)(dppb)(phen)]OAc (1) is easily prepared in 83% yield from [Ru(eta1-OAc)(eta2-OAc)(CO)(dppb)] (dppb = 1,4-bis(diphenylphosphino)butane) and 1,10-phenanthroline (phen) in MeOH.	Methanol	225-229	secreted phosphoprotein 1	Homo sapiens	43-47
30777444-1	2020	Meanwhile, EtOAc and n-BuOH fractions of MeOH extract of P. serpens L. show power activity against H460, HepG2, Hela, and PC9/GR cell lines, and no toxic effects against normal 16HBE cell lines.	Methanol	41-45	proprotein convertase subtilisin/kexin type 9	Homo sapiens	122-125
32565697-1	2020	In the current investigation, the active principles of the methanol extracts of Rhododendron arboreum leaves (MEL) and flowers (MEF) were investigated with the help of ultra-high performance liquid chromatography (UHPLC), amino acid analyzer and gas chromatography mass spectrometry (GC-MS).	Methanol	59-67	E74 like ETS transcription factor 4	Homo sapiens	128-131
32432586-2	2020	This reaction represents the first example of Ni-catalyzed dihydrocyanation of 1,3-enynes using TMSCN and MeOH as HCN surrogates.	Methanol	106-110	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	114-117
32436551-1	2020	Since a nucleophilic sp2 boron species can be generated in situ under the combined action of an inorganic base, B2pin2 and methanol, research on base-promoted nucleophilic borylation of unsaturated compounds has attracted significant attention.	Methanol	123-131	Sp2 transcription factor	Homo sapiens	21-24
32452684-1	2020	Low temperature anaerobic methane conversion to methanol (MTM) using copper ion-exchanged mordenite (Cu-MOR) as the catalyst and water as the sole source of oxygen is promising for sustainable utilization of methane.	Methanol	48-56	opioid receptor mu 1	Homo sapiens	104-107
32566932-6	2020	Composite membranes of PBI and phosphates, particularly in situ formed phosphosilicates in the polymer matrix, showed exceptionally stable conductivity at temperatures well above 200 C. Fuel cell tests at up to 260 C are reported operational with good tolerance of up to 16% CO in hydrogen, fast kinetics for direct methanol oxidation, and feasibility of nonprecious metal catalysts.	Methanol	316-324	submaxillary gland androgen regulated protein 3A	Homo sapiens	23-26
32310743-7	2020	His-tagged AdhX that was expressed in Escherichia coli and purified to homogeneity showed ADH activity towards methanol and other alcohols.	Methanol	111-119	NAD(P)-dependent alcohol dehydrogenase	Sphingobium japonicum UT26S	90-93
32380830-11	2020	The absorption spectrum of DCM in methanol is simulated from the computed spectral profiles of the isomers which indicates a distribution of trans1, trans2, cis1, and cis2 isomers as 33.5, 61.5, 2.0, and 3.0%, respectively.	Methanol	34-42	cytokine inducible SH2 containing protein	Homo sapiens	157-161
32380830-11	2020	The absorption spectrum of DCM in methanol is simulated from the computed spectral profiles of the isomers which indicates a distribution of trans1, trans2, cis1, and cis2 isomers as 33.5, 61.5, 2.0, and 3.0%, respectively.	Methanol	34-42	suppressor of cytokine signaling 2	Homo sapiens	167-171
32462212-0	2020	Toll of acute methanol poisoning for preventing COVID-19.	Methanol	14-22	toll like receptor 4	Homo sapiens	0-4
32383693-14	2020	plicatum MeOH extract for hCAI, hCAII, AChE, BChE, and alpha-glycosidase were found to be 77.87, 52.90, 115.50, 117.46, and 81.53 mg/mL, respectively.	Methanol	9-13	carbonic anhydrase 1	Homo sapiens	26-30
32374795-2	2020	Nickel(ii) complexes, 1-3, of these ligands HLa-c were synthesized in good yield (approximately 70%) by the reaction of ligands : (NiCl2 6H2O) in a 1 : 1 molar ratio in methanol.	Methanol	169-177	major histocompatibility complex, class I, C	Homo sapiens	44-49
32383693-14	2020	plicatum MeOH extract for hCAI, hCAII, AChE, BChE, and alpha-glycosidase were found to be 77.87, 52.90, 115.50, 117.46, and 81.53 mg/mL, respectively.	Methanol	9-13	carbonic anhydrase 2	Homo sapiens	32-37
32383693-14	2020	plicatum MeOH extract for hCAI, hCAII, AChE, BChE, and alpha-glycosidase were found to be 77.87, 52.90, 115.50, 117.46, and 81.53 mg/mL, respectively.	Methanol	9-13	acetylcholinesterase (Cartwright blood group)	Homo sapiens	39-43
32383693-14	2020	plicatum MeOH extract for hCAI, hCAII, AChE, BChE, and alpha-glycosidase were found to be 77.87, 52.90, 115.50, 117.46, and 81.53 mg/mL, respectively.	Methanol	9-13	butyrylcholinesterase	Homo sapiens	45-49
32874494-4	2020	This solvent effect is due to coordination of MeOH solvent in MeC+A4 8+ (i.e. exciplex formation) allowed by conformational flattening of the ligand sphere, which cannot occur in PhC+A4 8+ having bulkier Phphen ligand framework.	Methanol	46-50	C-C motif chemokine ligand 28	Homo sapiens	62-65
32461836-8	2020	Cell-free, tyrosinase inhibition experiments showed highest inhibition for L. vulpina methanol extract, followed by C. islandica chloroform-methanol one.	Methanol	86-94	tyrosinase	Homo sapiens	11-21
32215690-5	2020	Under the optimal conditions, the as-prepared MIL-Au NPs were applied to the SERS detection of clopidol in methanol and egg solution and its detection limits can be as low as to 0.5 mug/kg (equal to 0.5 ppb) in both solutions.	Methanol	107-115	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	77-81
32105506-2	2020	We show here that the irradiation of astrophysical ice analogues containing H2O, CH3OH, CO, and NH3 yields quantities of hexamethylenetetramine-methanol (hereafter HMT-methanol; C7N4H14O) that are easily detectible in the resulting organic residues.	Methanol	81-86	histamine N-methyltransferase	Homo sapiens	164-167
32105506-2	2020	We show here that the irradiation of astrophysical ice analogues containing H2O, CH3OH, CO, and NH3 yields quantities of hexamethylenetetramine-methanol (hereafter HMT-methanol; C7N4H14O) that are easily detectible in the resulting organic residues.	Methanol	144-152	histamine N-methyltransferase	Homo sapiens	164-167
32105506-2	2020	We show here that the irradiation of astrophysical ice analogues containing H2O, CH3OH, CO, and NH3 yields quantities of hexamethylenetetramine-methanol (hereafter HMT-methanol; C7N4H14O) that are easily detectible in the resulting organic residues.	Methanol	168-176	histamine N-methyltransferase	Homo sapiens	164-167
32105506-4	2020	As with HMT, HMT-methanol is likely to be an amino acid precursor.	Methanol	17-25	histamine N-methyltransferase	Homo sapiens	8-11
32105506-4	2020	As with HMT, HMT-methanol is likely to be an amino acid precursor.	Methanol	17-25	histamine N-methyltransferase	Homo sapiens	13-16
32105506-5	2020	HMT has tetrahedral (Td) symmetry, whereas HMT-methanol has C1 symmetry.	Methanol	47-55	histamine N-methyltransferase	Homo sapiens	43-46
32105506-6	2020	We report the computed expected infrared spectra for HMT and HMT-methanol obtained using ab initio quantum chemistry methods and show that there is a good match between the observed and computed spectra for regular HMT.	Methanol	65-73	histamine N-methyltransferase	Homo sapiens	61-64
32105506-6	2020	We report the computed expected infrared spectra for HMT and HMT-methanol obtained using ab initio quantum chemistry methods and show that there is a good match between the observed and computed spectra for regular HMT.	Methanol	65-73	histamine N-methyltransferase	Homo sapiens	61-64
32105506-7	2020	Since HMT-methanol lacks the high symmetry of HMT, it produces rotational transitions that could be observed at longer wavelengths, although establishing the exact positions of these transitions may be challenging.	Methanol	10-18	histamine N-methyltransferase	Homo sapiens	6-9
32105506-7	2020	Since HMT-methanol lacks the high symmetry of HMT, it produces rotational transitions that could be observed at longer wavelengths, although establishing the exact positions of these transitions may be challenging.	Methanol	10-18	histamine N-methyltransferase	Homo sapiens	46-49
32105506-8	2020	It is likely that HMT-methanol represents an abundant member of a larger family of functionalized HMT molecules that may be present in cold astrophysical environments.	Methanol	22-30	histamine N-methyltransferase	Homo sapiens	18-21
32105506-8	2020	It is likely that HMT-methanol represents an abundant member of a larger family of functionalized HMT molecules that may be present in cold astrophysical environments.	Methanol	22-30	histamine N-methyltransferase	Homo sapiens	98-101
32360999-11	2020	Transesterification reaction turned out 98% FAME conversion exerting catalyst dose (1.0 wt%), methanol to oil molar ratio (11:1), and reaction time (80 min) at reaction temperature (65  C) and agitation speed (600 rpm) featured by RSM study.	Methanol	94-102	benign adult familial myoclonic epilepsy 1	Homo sapiens	44-48
32290154-5	2020	The aim of this work is to synthesize naringenin-loaded silk fibroin nanoparticles (NAR-SFNs) by dissolving the SF in the ionic liquid 1-ethyl-3-methylimidazolium acetate, using high-power ultrasounds and rapid desolvation in methanol followed by the adsorption of NAR.	Methanol	226-234	fibroin light chain	Bombyx mori	61-68
31981394-5	2020	The thin MOR nanosheets, with highly exposed (010) planes and 8-membered ring (MR) windows therein, exhibited an extremely higher ethylene selectivity (42.1%) for methanol-to-olefin reactions when compared with conventional bulk MOR crystals (3.3%).	Methanol	163-171	opioid receptor mu 1	Homo sapiens	9-12
32149507-7	2020	For AM, AM2, and AM3, the structures with the methanol cyclic hydrogen bonded with [N1-C4(H6)] of acrylonitrile are more stable than the other H-bonded structures.	Methanol	46-54	adrenomedullin 2	Homo sapiens	8-11
32308768-7	2020	Results: Our design has smartness embodied in the aerogel circumvents the interference from methanol which is more ready to be catalyzed by AOX.	Methanol	92-100	acyl-CoA oxidase 1	Homo sapiens	140-143
31774616-1	2020	The first selective oxidation of methane to methanol is reported herein for zinc-exchanged MOR (Zn/MOR).	Methanol	44-52	opioid receptor mu 1	Homo sapiens	91-94
31774616-1	2020	The first selective oxidation of methane to methanol is reported herein for zinc-exchanged MOR (Zn/MOR).	Methanol	44-52	opioid receptor mu 1	Homo sapiens	99-102
32238605-11	2020	The methanol stem extract of P. nigrescens significantly (p <= 0.01) reduced MDA level;  significantly  (p <= 0.01) increased SOD activity;  non-significantly increased GSH activity and the activity of AChE apeared not altered.	Methanol	4-12	acetylcholinesterase	Mus musculus	202-206
32260181-0	2020	Ranunculus bulumei Methanol Extract Exerts Anti-Inflammatory Activity by Targeting Src/Syk in NF-kappaB Signaling.	Methanol	19-27	Rous sarcoma oncogene	Mus musculus	83-86
32260181-0	2020	Ranunculus bulumei Methanol Extract Exerts Anti-Inflammatory Activity by Targeting Src/Syk in NF-kappaB Signaling.	Methanol	19-27	spleen tyrosine kinase	Mus musculus	87-90
32260181-0	2020	Ranunculus bulumei Methanol Extract Exerts Anti-Inflammatory Activity by Targeting Src/Syk in NF-kappaB Signaling.	Methanol	19-27	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	94-103
31821902-1	2020	Pyranose oxidase (POx) is an FAD-dependent oxidoreductase, and like glucose oxidase (GOx) it is a member of the glucose-methanol-choline (GMC) superfamily of oxidoreductases.	Methanol	120-128	proline dehydrogenase 1	Homo sapiens	0-16
31821902-1	2020	Pyranose oxidase (POx) is an FAD-dependent oxidoreductase, and like glucose oxidase (GOx) it is a member of the glucose-methanol-choline (GMC) superfamily of oxidoreductases.	Methanol	120-128	proline dehydrogenase 1	Homo sapiens	18-21
31821902-1	2020	Pyranose oxidase (POx) is an FAD-dependent oxidoreductase, and like glucose oxidase (GOx) it is a member of the glucose-methanol-choline (GMC) superfamily of oxidoreductases.	Methanol	120-128	hydroxyacid oxidase 1	Homo sapiens	68-83
31821902-1	2020	Pyranose oxidase (POx) is an FAD-dependent oxidoreductase, and like glucose oxidase (GOx) it is a member of the glucose-methanol-choline (GMC) superfamily of oxidoreductases.	Methanol	120-128	hydroxyacid oxidase 1	Homo sapiens	85-88
32111036-4	2020	This study aimed to evaluate the anti-oxidative and anti-inflammatory properties of the methanol extract of SP leaves in tumor necrosis factor (TNF)-alpha-stimulated NCI-H292 cells and in a lipopolysaccharide (LPS)-induced acute lung injury (ALI) mouse model.	Methanol	88-96	tumor necrosis factor	Homo sapiens	121-154
32149521-1	2020	Density functional theory mechanistic study of the nickel-catalyzed reductive alkyne-alkyne cyclodimerization with CH3OH/BEt3 unveils that, after forming a nickel-alkyne pi complex, the reaction prefers outer-sphere proton transfer rather than the common alkyne-alkyne oxidative cyclization.	Methanol	115-120	trafficking protein particle complex subunit 3	Homo sapiens	121-125
32108462-7	2020	The main carbon-based photoreduction product of CdS/A-GO is CH3OH, whereas that of CdS/GO and CdS/P-GO is CO.	Methanol	60-65	CDP-diacylglycerol synthase 1	Homo sapiens	48-51
32141350-1	2022	In this study, the hepatoprotective activity of methanol bark extract of Alangium salviifolium (BEA) was evaluated for biochemical and histological parameters in swiss albino mice with CCl4-induced hepatotoxicity.	Methanol	48-56	chemokine (C-C motif) ligand 4	Mus musculus	185-189
32014631-2	2020	We found the methanol extract of Acalypha australis L. (AAL) to be the most effective.	Methanol	13-21	active avoidance learning	Mus musculus	56-59
32245131-4	2020	This study tested neuro-pharmacological, anti-nociceptive, and antidiarrheal activities by in vivo and in silico experiments for the metabolites extracted (methanol) from the leaves of Cuscuta reflexa (MECR).	Methanol	156-164	mitochondrial trans-2-enoyl-CoA reductase	Mus musculus	202-206
32093091-4	2020	High-performance liquid chromatography analysis of a CYP2E1 assay was developed on a reversed phase C18 column (SUPELCO 25 cm x 4.6 mm x 5 microm) at 282 nm using 60% H2O, 25% acetonitrile, and 15% methanol as mobile phase.	Methanol	198-206	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	53-59
31960837-1	2020	Herein, an environmentally friendly CoP/Zn2In2S5 catalyst is reported as a visible-light photocatalyst for the selective activation of the alpha-C-H bond of methanol to generate ethylene glycol with a selectivity of as high as 90%.	Methanol	157-165	caspase recruitment domain family member 16	Homo sapiens	36-39
32133339-5	2020	Meanwhile, the methanol permeability of the SPEN/UiO-66-NH2-x composite membrane had been effectively reduced due to the barrier effect of cross-linking and the addition of UiO-66-NH2-x.	Methanol	15-23	spen family transcriptional repressor	Homo sapiens	44-48
31759263-6	2020	The kinetic data in methanol and buffered aqueous solutions correlate well with the results of the test of catalase activity, thus showing that the rate determining step in the catalytic cycle corresponds to the initial reaction of the complexes with H2O2.	Methanol	20-28	catalase	Homo sapiens	107-115
31925490-7	2020	The highest recoveries (> 95%) were obtained with 50 mg of the phenyl group support (CS2) at pH 5, using 5 mL of the sample and carbon tetrachloride and methanol, as extraction and dispersive solvents, respectively.	Methanol	153-161	chorionic somatomammotropin hormone 2	Homo sapiens	85-88
31669668-10	2020	The methanol extract of the plant prevented the diabetogenic effect of STZ and significantly lowered the fasting blood glucose level, glycated haemoglobin and increased insulin and C-peptide level in treated rats.	Methanol	4-12	insulin 2	Rattus norvegicus	181-190
32013559-7	2021	Samples showed a low capacity to inhibit alpha-amylase, but a high alpha-glucosidase inhibition was obtained with the root"s and flower"s ethanol extracts, and flower"s methanol extract.	Methanol	169-177	sucrase-isomaltase	Homo sapiens	67-84
31715395-1	2020	To efficiently and selectively produce liquid hydrocarbon fuels, e.g., methanol, by CO2 photoelectrochemical reduction, CdS nanoparticles (NPs) anchored on the nitrogen-doped carbon particles (NCP) with core-shell dodecahedral porous structure were used as cathode catalysts.	Methanol	71-79	CDP-diacylglycerol synthase 1	Homo sapiens	120-123
31715395-4	2020	CdS/NCP-500 catalyst exhibited a selectivity of 77.3% towards methanol with a total carbon atom conversion rate of 3052 nmol h-1 cm-2.	Methanol	62-70	CDP-diacylglycerol synthase 1	Homo sapiens	0-3
31715395-6	2020	NCP, exhibiting a high adsorption capacity for CO2, allowed the conversion of COOH* into CO* (DeltaE = -3.6 eV), which was then transferred to the CdS surface displaying abundant S-vacancies for the reduction into the methanol product.	Methanol	218-226	CDP-diacylglycerol synthase 1	Homo sapiens	147-150
31766103-0	2020	Velvet antler methanol extracts (MEs) protects against oxidative stress in Caenorhabditis elegans by SKN-1.	Methanol	14-22	BZIP domain-containing protein;Protein skinhead-1	Caenorhabditis elegans	101-106
31968662-4	2020	The reaction of NB-2 with peroxyl radicals was further studied via fluorescence measurements in methanol, with alpha,alpha"-azobisisobutyronitrile (AIBN) used as a source of radicals generated by photolysis or thermolysis, and in the micellar system at pH 7.4, with 2,2"-azobis(2-amidinopropane) (ABAP) used as a thermal source of the radicals.	Methanol	96-104	contactin 5	Homo sapiens	16-20
31968662-5	2020	The reaction of NB-2 receptors with peroxyl radicals manifests itself by the strong increase of a fluorescence with a maximum at 612-616 nm, with a 14-fold enhancement of emission in methanol and a 4-fold enhancement in the micelles, as compared to the unoxidized probe.	Methanol	183-191	contactin 5	Homo sapiens	16-20
31850427-6	2020	The L10-PtZn nanoparticles embedded in a hollow carbon nanocage obtained from one-step annealing of Pt2+-exchanged ZIF-8 showed better electrocatalytic activity and durability toward methanol oxidation under acidic electrolyte conditions than those obtained from commercial Pt/C catalysts.	Methanol	183-191	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	4-7
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Methanol	138-146	protein phosphatase 4 catalytic subunit	Homo sapiens	17-21
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Methanol	138-146	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Methanol	138-146	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-3	2020	Complex 4 is also readily produced by the reaction of [Ir(PPh3)3Cl] and Hdpp in the presence of KOtBu under refluxing methanol or by the reaction of IrCl3 and PPh3 in refluxing 2-ethoxyethanol.	Methanol	118-126	protein phosphatase 4 catalytic subunit	Homo sapiens	58-62
31763820-5	2020	A BMP-SA-Biotin-Nb3-based enzyme linked immunosorbent assay (ELISA) for TBBPA dissolved in methanol was developed, showing a half-maximum inhibition concentration (IC50) of 0.42 ng mL-1.	Methanol	91-99	L1 cell adhesion molecule	Mus musculus	181-185
32290926-3	2020	2 mol/L methanol solution of hydrochloric acid.	Methanol	8-16	thrombopoietin	Mus musculus	6-7
31867858-3	2020	Their interface-dependent performance on methanol and ethanol oxidation reaction (MOR and EOR) is clearly observed.	Methanol	41-49	opioid receptor mu 1	Homo sapiens	82-85
32009081-4	2020	Significant c-Met kinase activity was observed in 30, 40, and 50% methanol (MeOH) eluate fractions obtained from water extract of EHE using Diaion HP-20 column chromatography.	Methanol	66-74	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	12-17
32009081-4	2020	Significant c-Met kinase activity was observed in 30, 40, and 50% methanol (MeOH) eluate fractions obtained from water extract of EHE using Diaion HP-20 column chromatography.	Methanol	76-80	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	12-17
32612092-8	2020	In addition, we demonstrated that the methanol extract of foxtail millet up-regulated BDNF levels in ACHN cells.	Methanol	38-46	brain derived neurotrophic factor	Homo sapiens	86-90
31897190-7	2020	However, HMGB1 was also associated with interphase (but not mitotic chromosomes) when fixed with chilled methanol and 5% (v/v) acetic acid or PFA in vitro.	Methanol	105-113	high mobility group box 1	Homo sapiens	9-14
32880146-5	2020	The patient with methanol intoxication after use of ethanol containing alcohol had retained his visual functions; he was found to have microcysts and RNFL thinning during the first few months after the intoxication, but they were within normal range of OCT parameters.	Methanol	17-25	plexin A2	Homo sapiens	253-256
32290926-5	2020	3 mol/L methanol solution of potassium hydroxide, was separated with 5%-phenyl-methyl polysiloxane(HP-5)(25 mx0.	Methanol	8-16	thrombopoietin	Mus musculus	6-7
31769683-9	2019	The intramolecular charge transfer of the compounds containing the -NMe2 and -CN groups is predominant in methanol, resulting in large Stokes shift and oscillator strength.	Methanol	106-114	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	68-72
31697295-3	2019	One of the two coordinating methanol molecules in {[CoII(CH3OH)2][PtIV(SCN)6]}n was replaced with pyridine to stabilise the open metal sites, because the methanol molecules are too labile to maintain open metal sites in water.	Methanol	28-36	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	52-56
31765121-16	2019	For elementary steps of the industrially important methanol-to-olefin process, our hybrid MP2:PBE+D+DeltaCC calculations yield rate constants in agreement with experiment within chemical accuracy limits, finally achieving for molecule-surface reactions which was possible so hitherto only for gas phase reactions involving not more than 10 atoms.	Methanol	51-59	tryptase pseudogene 1	Homo sapiens	90-93
31847463-3	2019	In this work, in vivo and in silico studies were conducted to evaluate their methanol extracts potential to alleviate liver damage in CCl4-intoxicated rats, in addition to their antioxidant activity and identifying the molecular mechanisms of their phenolic constituents.	Methanol	77-85	C-C motif chemokine ligand 4	Rattus norvegicus	134-138
31697295-3	2019	One of the two coordinating methanol molecules in {[CoII(CH3OH)2][PtIV(SCN)6]}n was replaced with pyridine to stabilise the open metal sites, because the methanol molecules are too labile to maintain open metal sites in water.	Methanol	154-162	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	52-56
31714790-2	2019	In the presence of 13 mol % of Ni(cod)2 and 10 mol % DPEphos, both tryptophols and tryptamines could react with aryl vinyl carbinols smoothly under mild conditions, affording 3-cinnamyl indolines in moderate to good yields with high chemo- and regioselectivity.	Methanol	112-132	COD2	Homo sapiens	31-39
31717480-4	2019	In the second step, methanol in the presence of potassium carbonate as a catalyst was used under conventional heating or microwave irradiation, which provided an eco-friendly method to afford the target products in excellent yields and purities.	Methanol	20-28	ciliogenesis associated kinase 1	Homo sapiens	8-11
31306961-4	2019	The spectroscopic responses of probe to pH variations were investigated in CH3OH/PBS (v/v, 1:1) mixed solution at different pH values.	Methanol	75-80	phenylalanine hydroxylase	Homo sapiens	40-42
31336240-2	2019	In this work, the removal of rhamnolipid-solubilized hexadecane via a salicylic acid-methanol-acetone modified steel converter slag (SMA-SCS) catalyzed Fenton-like process was studied.	Methanol	85-93	survival of motor neuron 1, telomeric	Homo sapiens	133-136
31428909-2	2019	As expected, LPS stimulation of the animals significantly increased serum and intra-testicular interleukin-6 and serum nitrite levels which were significantly inhibited in the Eth-OH + LPS and Meth + LPS animals.	Methanol	193-197	interleukin 6	Rattus norvegicus	95-108
31068038-0	2019	Methanol extract of Muntingia calabura leaves attenuates CCl4-induced liver injury: possible synergistic action of flavonoids and volatile bioactive compounds on endogenous defence system.	Methanol	0-8	C-C motif chemokine ligand 4	Rattus norvegicus	57-61
31068038-2	2019	OBJECTIVE: This study investigates the effect of methanol extract of M. calabura leaves (MMCL) on hepatic antioxidant and anti-inflammatory activities in CCl4-induced hepatotoxic rat.	Methanol	49-57	C-C motif chemokine ligand 4	Rattus norvegicus	154-158
31769895-4	2020	Owing to the presence of sulfide interfaces, the PtNiCo/NiCoS IFNWs enable an impressive methanol/ethanol oxidation reaction (MOR/EOR) performance and excellent anti-CO poisoning tolerance.	Methanol	89-97	opioid receptor mu 1	Homo sapiens	126-129
31603652-8	2019	In addition to proof-of-concept we further improved the host strain by deleting a gene (frmA) responsible for the conversion of HCHO to formate, thereby increasing the production of 1,3-PDO from 298.3 +- 11.4 mg/L to 508.3 +- 9.1 mg/L and from 3.8 mg/L to 32.7 +- 0.8 mg/L with HCHO and methanol as co-substrate of glucose fermentation, respectively.	Methanol	287-295	alcohol dehydrogenase class-III	Escherichia coli	88-92
31419499-0	2019	Viburnum pichinchense methanol extract exerts anti-inflammatory effects via targeting the NF-kappaB and caspase-11 non-canonical inflammasome pathways in macrophages.	Methanol	22-30	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	90-99
31696984-3	2019	Such a unique metal configuration of Rh1 /PIP leads to excellent performance in vapor-phase methanol carbonylation, outperforming commercial homo- and heterogeneous catalysts.	Methanol	92-100	prolactin induced protein	Homo sapiens	42-45
31660548-4	2019	In this study, planar mononuclear Ni(L1)2 (L1 = 2-ethoxy-6-(iminomethyl)phenol) was dissolved in methanol and combined with Dy(NO3)3 6H2O for 48 h at room temperature to obtain a butterfly-like Ni2Dy2 cluster ([Dy2Ni2(L1)4(CH3O)2(NO3)4], 1).	Methanol	97-105	LINE1 retrotransposable element 1	Homo sapiens	34-41
31553114-2	2019	Herein, the first dinuclear cluster species, RhVO 3 - , has been designed to mediate the co-conversion of CH 4 and CO 2 to oxygenated products, CH 3 OH and CH 2 O, in the temperature range of 393-600 K. The resulting cluster ions RhVO 3 CO - after CH 3 OH formation can further desorb the [CO] unit to regenerate the RhVO 3 - cluster, leading to the successful establishment of a catalytic cycle for methanol production from CH 4 and CO 2 (CH 4 + CO 2 = CH 3 OH + CO).	Methanol	400-408	complement C2	Homo sapiens	115-119
31775347-4	2019	High performance liquid chromatography analysis of a CYP2C11 assay was developed on a reversed phase C18 column (SUPELCO 25 cm x 4.6 mm x 5 microm) at 243 nm using 32% phosphate buffer (pH 3.36) and 68% methanol as a mobile phase.	Methanol	203-211	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	53-60
31621714-3	2019	Methanol was identified as an appropriate solvent for non-aqueous degradation applications and demonstrated to support the MOF-based destruction of both sarin and soman.	Methanol	0-8	lysine acetyltransferase 8	Homo sapiens	123-126
34055308-0	2019	Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats.	Methanol	0-8	C-C motif chemokine ligand 4	Rattus norvegicus	48-52
34055308-1	2019	We have investigated the protective potential of methanol extract of Iphiona aucheri (IAM) on the expression of endoplasmic reticulum (ER) stress associated genes and inflammatory genes on carbon tetrachloride (CCl4) induced hepatic toxicity in rats.	Methanol	49-57	C-C motif chemokine ligand 4	Rattus norvegicus	211-215
31325603-9	2019	Significant differences were found between the peritoneal TNF-alpha, VEGF, and IL-6 levels of MeOH extract treated group and those of control group.	Methanol	94-98	interleukin 6	Rattus norvegicus	79-83
31489680-4	2019	In this study, we have investigated aphrodisiac potential of A. pannosum stem bark methanol extract (APM) in rat.	Methanol	83-91	alanyl aminopeptidase, membrane	Rattus norvegicus	101-104
31753071-1	2019	Proton reduction by [CoII(BPyPy2COH)(OH2)2]2+ (BPyPy2COH = [2,2"-bipyridin]-6-yl-di[pyridin-2-yl]methanol) proceeds through two distinct, pH-dependent pathways involving proton-coupled electron transfer (PCET), reduction and protonation steps.	Methanol	59-105	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	21-25
31487145-5	2019	The production of methanol through chemical recycling of captured CO2 is at the heart of the so-called "methanol economy" that we have proposed with the late Prof. George Olah at our Institute.	Methanol	18-26	oleoyl-ACP hydrolase	Homo sapiens	171-175
31649341-3	2019	ratio) nanoboxes supported on functionalized Vulcan carbon (Pt-Ni/C-R2) were synthesized through a facile method for the efficient electrooxidation of methanol.	Methanol	151-159	complement C3d receptor 2	Homo sapiens	66-70
31649341-9	2019	The experimental results were supported by Density Functional Theory (DFT) studies, which revealed that the lowest CO poisoning of the Pt1Ni1 catalyst among all Ptm-Nin mixing ratios may account for the enhanced methanol oxidation.	Methanol	212-220	ninein	Homo sapiens	165-168
31487145-5	2019	The production of methanol through chemical recycling of captured CO2 is at the heart of the so-called "methanol economy" that we have proposed with the late Prof. George Olah at our Institute.	Methanol	104-112	oleoyl-ACP hydrolase	Homo sapiens	171-175
31479580-4	2019	Herein, we report longitudinal relaxation times (T1 ) and lifetimes of pH2 ( tau P O C   ) in methanol and water, with or without O2 , NaCl, rhodium-catalyst or human blood.	Methanol	94-102	polyhomeotic homolog 2	Homo sapiens	71-74
31667368-8	2019	Over-expression of MIG3 enabled improved growth in the presence of methanol, suggesting that MIG3 is a mediator of the superior CEN.PK strain growth.	Methanol	67-75	Mig3p	Saccharomyces cerevisiae S288C	19-23
31549708-3	2019	In these complexes, LH3 is either monodeprotonated (1) or a mixture of mono- and doubly-deprotonated ligands (2 and 3) binding lanthanide ions via Ndiazine, Ohydrazone, and Ovanillin donors, while the remaining vacant coordination sites are occupied by OMeOH (1), Ohydroxide (2) and methoxides (3).	Methanol	283-293	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	Homo sapiens	20-23
31341033-6	2019	This result, coupled with previous evidence that RITA is a SULT1A1 substrate, suggests that carbinol modification by a sulfate leaving group and subsequent formation of a reactive carbocation may explain RITA"s broad cytotoxicity.	Methanol	92-100	RBPJ interacting and tubulin associated 1	Mus musculus	49-53
31484099-2	2019	Sample of whole blood with volume of 50 muL was prepared by a protein precipitation with methanol and 0.5 mol.	Methanol	89-97	tripartite motif containing 37	Homo sapiens	40-43
31341033-6	2019	This result, coupled with previous evidence that RITA is a SULT1A1 substrate, suggests that carbinol modification by a sulfate leaving group and subsequent formation of a reactive carbocation may explain RITA"s broad cytotoxicity.	Methanol	92-100	sulfotransferase family 1A, phenol-preferring, member 1	Mus musculus	59-66
31341033-6	2019	This result, coupled with previous evidence that RITA is a SULT1A1 substrate, suggests that carbinol modification by a sulfate leaving group and subsequent formation of a reactive carbocation may explain RITA"s broad cytotoxicity.	Methanol	92-100	RBPJ interacting and tubulin associated 1	Mus musculus	204-208
31611922-0	2019	Anti-Inflammatory Effects of Licania macrocarpa Cuatrec Methanol Extract Target Src- and TAK1-Mediated Pathways.	Methanol	56-64	Rous sarcoma oncogene	Mus musculus	80-83
31572064-6	2019	Hence, targeting CD146 expression by utilization of methanol extracts of Calotropis procera leaf may be useful for the treatment of carcinogenesis.	Methanol	52-60	melanoma cell adhesion molecule	Homo sapiens	17-22
31616837-2	2019	Especially, the composite membranes were prepared by growing ZIF-8 nanoparticles on one side of the PIM-1 membrane in methanol.	Methanol	118-126	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	100-105
31540477-1	2019	LC-ESI-MS (Liquid Chromatography coupled with Electrospray Ionization Mass Spectrometry profiling of a methanol extract from Buddleia indica (BIM) leaves revealed 12 main peaks in which verbascoside and buddlenoid B represent the major compounds.	Methanol	103-111	Bcl2-like 11	Rattus norvegicus	142-145
31611922-0	2019	Anti-Inflammatory Effects of Licania macrocarpa Cuatrec Methanol Extract Target Src- and TAK1-Mediated Pathways.	Methanol	56-64	mitogen-activated protein kinase kinase kinase 7	Mus musculus	89-93
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Methanol	54-62	caveolin 1	Homo sapiens	27-31
31347642-2	2019	The Ni(ii) complexes (Ni4Gd, Solv = MeOH; Ni4Dy, Solv = MeCN) are not SMMs in the absence of an applied dc field.	Methanol	36-40	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	7-9
31511569-2	2019	In this study, gas chromatography coupled with mass spectrometry (GC-MS) was employed for the determination of signatures found in ER+/PR+ breast cancer cells derived from MCF-7 using different extraction solvents including: A, formic acid in water; B, ammonium hydroxide in water; C, ethyl acetate; D, methanol: water (1:1, v/v); and E, acetonitrile: water (1:1, v/v).	Methanol	303-311	epiregulin	Homo sapiens	131-133
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Methanol	54-62	caveolin 1	Homo sapiens	107-111
31398017-3	2019	A RuII-hydrido species was detected by 1H NMR and electrospray ionization (ESI)-time-of-flight (TOF)-MS measurements as an intermediate to react with olefins, and CoII-bound methanol was suggested to act as a proton source.	Methanol	174-182	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	163-167
31564995-6	2019	Results: C. crepidioides leaf methanol extract and fractions significantly (P&lt;0.05) prolonged the clotting time, prothrombin and activated partial thromboplastin times in the blood obtained from the volunteers.	Methanol	30-38	coagulation factor II, thrombin	Homo sapiens	116-127
31348650-4	2019	This CuSAs/TCNFs membrane has excellent mechanical properties and can be directly used as cathode for CO2RR, which could generate nearly pure methanol with 44% Faradaic efficiency in liquid phase.	Methanol	142-150	complement C2	Homo sapiens	102-107
31813873-2	2019	In this study, we investigated the effect of spicatoside A isolated from LT methanol extract on ovalbumin (OVA)-sensitized/challenged asthmatic mice.	Methanol	76-84	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	96-105
31426544-7	2019	Growth of pex11 inp2 cells on methanol, a growth substrate that requires functional peroxisomes, is retarded relative to the wild type control.	Methanol	30-38	Pex11p	Saccharomyces cerevisiae S288C	10-15
31426544-7	2019	Growth of pex11 inp2 cells on methanol, a growth substrate that requires functional peroxisomes, is retarded relative to the wild type control.	Methanol	30-38	Inp2p	Saccharomyces cerevisiae S288C	16-20
31148251-3	2019	Using DBU as the organic base for the reaction of acetone, chloroform and methanol in acetonitrile afforded MMA in 66 % yield.	Methanol	74-82	monocyte to macrophage differentiation associated	Homo sapiens	108-111
31438541-3	2019	Here, the Nrf2-activating effect of the crude methanol extract of dried leaves of Pogostemon cablin Bentham was demonstrated by measuring the antioxidant response element (ARE)-driven luciferase activity and pachypodol, 4",5-dihydroxy-3,3",7-trimethoxyflavone, was isolated by bioactivity-guided fractionation and further separation using chromatographic techniques.	Methanol	46-54	NFE2 like bZIP transcription factor 2	Homo sapiens	10-14
31287958-2	2019	The methanol/ethanol oxidation reaction (MOR/EOR) often requires high-performance yet expensive Pt-based catalysts that may be easily poisoned.	Methanol	4-12	opioid receptor mu 1	Homo sapiens	41-44
31085226-10	2019	T. chamaedrys methanol extract inhibits mRNA expression of CYP1A1, CYP1B1, GSTP1, MRP1 and MRP2 in SW480 cells.	Methanol	14-22	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	59-65
31206996-3	2019	The L10 -structure stabilizes Co and significantly enhances the catalysis of the PtAu surface towards electro-oxidation of ethanol, methanol, and formic acid, with mass activities of 1.55 A/mgPt , 1.49 A/mgPt , and 11.97 A/mgPt , respectively in 0.1 m HClO4 .	Methanol	132-140	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	4-7
31085226-10	2019	T. chamaedrys methanol extract inhibits mRNA expression of CYP1A1, CYP1B1, GSTP1, MRP1 and MRP2 in SW480 cells.	Methanol	14-22	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	67-73
31085226-10	2019	T. chamaedrys methanol extract inhibits mRNA expression of CYP1A1, CYP1B1, GSTP1, MRP1 and MRP2 in SW480 cells.	Methanol	14-22	glutathione S-transferase pi 1	Homo sapiens	75-80
31085226-10	2019	T. chamaedrys methanol extract inhibits mRNA expression of CYP1A1, CYP1B1, GSTP1, MRP1 and MRP2 in SW480 cells.	Methanol	14-22	ATP binding cassette subfamily C member 1	Homo sapiens	82-86
31401705-9	2019	Following their elution from the sorbent with a mixture of acetonitrile and methanol, the limits of quantification reached are between 4.6 and 400 mug L-1.	Methanol	76-84	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
31397186-1	2021	The present study aimed to investigate the preventive effects of methanol fraction from Cassia angustifolia leaf extract (MECA), associated with its phytochemical content, on CCl4-induced hepatic toxicity in adult rats.	Methanol	65-73	C-C motif chemokine ligand 4	Rattus norvegicus	175-179
31085226-10	2019	T. chamaedrys methanol extract inhibits mRNA expression of CYP1A1, CYP1B1, GSTP1, MRP1 and MRP2 in SW480 cells.	Methanol	14-22	ATP binding cassette subfamily C member 2	Homo sapiens	91-95
31187818-6	2019	For the reaction of syn-CH3CHOO with methanol vapor, the observed rate coefficients show a quadratic dependence on [CH3OH], indicating that two methanol molecules participate in the reaction.	Methanol	37-45	synemin	Homo sapiens	20-23
31522674-9	2019	These changes were reversible, which corroborates the conclusion on the CytC transition to the molten globule conformation in methanol-containing solutions.	Methanol	126-134	cytochrome c, somatic	Homo sapiens	72-76
31093638-0	2019	Ambient and high-pressure kinetic investigation of methanol substitution in fac-[Re(Trop)(CO)3(MeOH)] by different monodentate nucleophiles.	Methanol	51-59	FA complementation group C	Homo sapiens	76-79
31093638-0	2019	Ambient and high-pressure kinetic investigation of methanol substitution in fac-[Re(Trop)(CO)3(MeOH)] by different monodentate nucleophiles.	Methanol	95-99	FA complementation group C	Homo sapiens	76-79
31093638-3	2019	High-pressure kinetic studies with four of these entering nucleophiles in methanol at 25  C on fac-[Re(Trop)(CO)3(MeOH)] yielded the following activation volumes, DeltaV (kL), for the ligation by four nucleophiles as defined by kL (cm3 mol-1): Im: 9.0 +- 0.2; Py: 10.1 +- 0.2; TU: 10.0 +- 0.3 and MeTU: 14.5 +- 0.3.	Methanol	74-82	FA complementation group C	Homo sapiens	95-98
31093638-3	2019	High-pressure kinetic studies with four of these entering nucleophiles in methanol at 25  C on fac-[Re(Trop)(CO)3(MeOH)] yielded the following activation volumes, DeltaV (kL), for the ligation by four nucleophiles as defined by kL (cm3 mol-1): Im: 9.0 +- 0.2; Py: 10.1 +- 0.2; TU: 10.0 +- 0.3 and MeTU: 14.5 +- 0.3.	Methanol	114-118	FA complementation group C	Homo sapiens	95-98
31853359-2	2019	Addition of PR3 (PR3 = PMe3, PMe2Ph, PMePh2, PPh3) to a neutral methoxide-bridged polyoxovanadate-alkoxide (POV-alkoxide) cluster, [V6O7(OMe)12]0, results in isolation of a reduced structure with phosphine oxide datively coordinated to a site-differentiated VIII ion.	Methanol	64-106	proteinase 3	Homo sapiens	12-15
30885661-3	2019	In this work, IBU is dissolved in methanol and then treated with a Co(II) aqueous solution, forming a blue complex which is extractable by dispersive liquid-liquid microextraction.	Methanol	34-42	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	67-73
31340430-4	2019	Longer crystallization times with a Co(NCS)2 to 2 molar ratio of 1:1 yielded crystals of [Co(2)(NCS)2(MeOH)2]n (1D-chain) and the pseudopolymorphs [{Co(2)2(NCS)2} 3MeOH]n and [{Co(2)2(NCS)2} 2.2CHCl3]n ((4,4)-nets), each type of crystal originating from a different zone in the crystallization tube.	Methanol	102-106	cytosolic thiouridylase subunit 2	Homo sapiens	39-44
31340430-4	2019	Longer crystallization times with a Co(NCS)2 to 2 molar ratio of 1:1 yielded crystals of [Co(2)(NCS)2(MeOH)2]n (1D-chain) and the pseudopolymorphs [{Co(2)2(NCS)2} 3MeOH]n and [{Co(2)2(NCS)2} 2.2CHCl3]n ((4,4)-nets), each type of crystal originating from a different zone in the crystallization tube.	Methanol	102-106	cytosolic thiouridylase subunit 2	Homo sapiens	96-101
31340430-4	2019	Longer crystallization times with a Co(NCS)2 to 2 molar ratio of 1:1 yielded crystals of [Co(2)(NCS)2(MeOH)2]n (1D-chain) and the pseudopolymorphs [{Co(2)2(NCS)2} 3MeOH]n and [{Co(2)2(NCS)2} 2.2CHCl3]n ((4,4)-nets), each type of crystal originating from a different zone in the crystallization tube.	Methanol	102-106	cytosolic thiouridylase subunit 2	Homo sapiens	96-101
31340430-4	2019	Longer crystallization times with a Co(NCS)2 to 2 molar ratio of 1:1 yielded crystals of [Co(2)(NCS)2(MeOH)2]n (1D-chain) and the pseudopolymorphs [{Co(2)2(NCS)2} 3MeOH]n and [{Co(2)2(NCS)2} 2.2CHCl3]n ((4,4)-nets), each type of crystal originating from a different zone in the crystallization tube.	Methanol	102-106	cytosolic thiouridylase subunit 2	Homo sapiens	96-101
31215575-5	2019	Moreover, the MOF shows higher durability with &gt;70% performance retention after 25 hours of reaction and tolerance towards methanol; this demonstrates its potential for application in direct methanol fuel cells (DMFCs); furthermore, due to the availability of more active sites and accessible surface area, the Co-MOF performs well towards the OER with lower onset potential and small Tafel slope as compared to the commercial RuO2 nanoparticles.	Methanol	126-134	lysine acetyltransferase 8	Homo sapiens	14-17
31215575-5	2019	Moreover, the MOF shows higher durability with &gt;70% performance retention after 25 hours of reaction and tolerance towards methanol; this demonstrates its potential for application in direct methanol fuel cells (DMFCs); furthermore, due to the availability of more active sites and accessible surface area, the Co-MOF performs well towards the OER with lower onset potential and small Tafel slope as compared to the commercial RuO2 nanoparticles.	Methanol	194-202	lysine acetyltransferase 8	Homo sapiens	14-17
31187818-6	2019	For the reaction of syn-CH3CHOO with methanol vapor, the observed rate coefficients show a quadratic dependence on [CH3OH], indicating that two methanol molecules participate in the reaction.	Methanol	116-121	synemin	Homo sapiens	20-23
31187818-6	2019	For the reaction of syn-CH3CHOO with methanol vapor, the observed rate coefficients show a quadratic dependence on [CH3OH], indicating that two methanol molecules participate in the reaction.	Methanol	144-152	synemin	Homo sapiens	20-23
31187818-10	2019	The reaction of syn-CH3CHOO with one CH3OH molecule was not observed in the studied concentration range.	Methanol	37-42	synemin	Homo sapiens	16-19
31071579-10	2019	The SPE (MeOH:H2O 70:30 with C18 cartridges) samples showed greater in vitro cytotoxicity than the crude extracts, with IC50 ranging from 8.01 to 94.92 mug mL-1 against the tumor lines tested.	Methanol	9-13	L1 cell adhesion molecule	Mus musculus	156-160
30951845-0	2019	Anti-inflammatory activities of Canarium subulatum Guillaumin methanol extract operate by targeting Src and Syk in the NF-kappaB pathway.	Methanol	62-70	Rous sarcoma oncogene	Mus musculus	100-103
31054084-4	2019	In this study, a methanol-free expression platform for extracellular expression of hGM-CSF was developed.	Methanol	17-25	colony stimulating factor 2	Homo sapiens	83-90
30952319-3	2019	Interestingly, the obtained chemosensor exhibited much better fluorescence detection sensitivity and selectivity toward Cd2+ in acidic 10% methanol aqueous solution (pH 4) comparing to those in neutral environment.	Methanol	139-147	CD2 molecule	Homo sapiens	120-123
30951845-0	2019	Anti-inflammatory activities of Canarium subulatum Guillaumin methanol extract operate by targeting Src and Syk in the NF-kappaB pathway.	Methanol	62-70	spleen tyrosine kinase	Mus musculus	108-111
31460116-4	2019	Aromatic benzyl ethers; aromatic and aliphatic N-Cbzs; and aromatic carbonyl groups were smoothly hydrogenated in the presence of 1-5 mol % of Pd/TAm in MeOH or 2-PrOH.	Methanol	153-157	Myeloproliferative syndrome, transient (transient abnormal myelopoiesis)	Homo sapiens	146-149
30963643-3	2019	The complexes [Pd](PF6 ) and [Pt](PF6 ) adopt monomeric structures and are stable in CH2 Cl2 and toluene, whereas they gradually disproportionate at room temperature to [M] and 3,5-di-tert-butylbenzoquinone (3,5-DTBBQ) in polar solvents such as THF, MeOH, EtOH, DMF, or DMSO.	Methanol	250-254	sperm associated antigen 17	Homo sapiens	19-22
30963643-3	2019	The complexes [Pd](PF6 ) and [Pt](PF6 ) adopt monomeric structures and are stable in CH2 Cl2 and toluene, whereas they gradually disproportionate at room temperature to [M] and 3,5-di-tert-butylbenzoquinone (3,5-DTBBQ) in polar solvents such as THF, MeOH, EtOH, DMF, or DMSO.	Methanol	250-254	sperm associated antigen 17	Homo sapiens	34-37
31214899-1	2019	Fomepizole is used as an antidote to treat methanol poisoning due to its selectivity towards alcohol dehydrogenase.	Methanol	43-51	aldo-keto reductase family 1 member A1	Homo sapiens	93-114
31202228-3	2019	Here, using time-resolved X-ray liquidography, we revisit the photodissociation mechanism of CH2I2 in methanol and determine the structures of all transient species and photoproducts involved in its photodissociation and reveal that I2 - and I3 - are formed via heterolysis of iso-CH2I-I in the photodissociation of CH2I2 in methanol.	Methanol	325-333	brain protein I3	Homo sapiens	233-244
30451020-12	2019	ApoE4 allele carriers demonstrated lower RNFL thickness, longer P1 latency, and more frequent methanol-induced brain damage compared to non-carriers.	Methanol	94-102	apolipoprotein E	Homo sapiens	0-5
31049529-0	2019	A robust etb-type metal-organic framework showing polarity-exclusive adsorption of acetone over methanol for their azeotropic mixture.	Methanol	96-104	endothelin receptor type B	Homo sapiens	9-12
31231639-8	2019	The only detected reduction product by GC analysis is CO: for example, fac-Re (bpy-4,4"-NMe2)(CO)3Cl gives CO with high faradic efficiency and a TON of 18 and 31, in absence of external proton source and with 5% MeOH, respectively.	Methanol	212-216	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	88-92
30681097-5	2019	For example, PDI-TAB forms fibers of finite length when bulk powder is dispersed in methanol; it shows flexible lengthy 1D fibers when dichloromethane solution of PDI-TAB is injected into methanol solvent.	Methanol	84-92	peptidyl arginine deiminase 1	Homo sapiens	13-16
30870730-0	2019	Sub-1 nm PtSn ultrathin sheet as an extraordinary electrocatalyst for methanol and ethanol oxidation reactions.	Methanol	70-78	SUB1 regulator of transcription	Homo sapiens	0-5
30870730-1	2019	Sub-1 nm PtSn nanosheets of 0.6-0.9 nm in thickness were synthesized via a solution colloidal method and were applied as electrooxidation catalysts for methanol oxidation reaction (MOR) and ethanol oxidation (EOR) in alkaline and acid environments.	Methanol	152-160	SUB1 regulator of transcription	Homo sapiens	0-5
30954631-7	2019	The metabolic profiling of both atria from relaxin-2-treated and control rats was carried out using two separate ultra-high performance liquid chromatography (UHPLC)-Time of Flight-MS based platforms analyzing methanol and chloroform/methanol extracts combined with a UHPLC-single quadrupole-MS based platform used to analyze aminoacids and with a methanol/water extract platform that covered polar metabolites.	Methanol	234-242	relaxin 2	Homo sapiens	43-52
30954631-7	2019	The metabolic profiling of both atria from relaxin-2-treated and control rats was carried out using two separate ultra-high performance liquid chromatography (UHPLC)-Time of Flight-MS based platforms analyzing methanol and chloroform/methanol extracts combined with a UHPLC-single quadrupole-MS based platform used to analyze aminoacids and with a methanol/water extract platform that covered polar metabolites.	Methanol	234-242	relaxin 2	Homo sapiens	43-52
31353615-10	2019	Methanol extract, hexane, and ethyl acetate fractions and three polymethoxyflavonoids showed a significant inhibitory activity against expression of IL-1beta mRNA.	Methanol	0-8	interleukin 1 alpha	Mus musculus	149-157
30981185-11	2019	RESULTS: Passively diffused constituents of the methanol acai extract (IC50 of 28.03 microg/microl) demonstrated the highest inhibition potential, and, at 1.5 microg/microl, induced significant changes in CYP3A4 gene expression.	Methanol	48-56	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	205-211
30981185-15	2019	CONCLUSION: The passively absorbable portion of a methanol acai extract exhibited inhibition and induction effects on CYP3A4 suggesting the potential to produce botanical-drug interactions.	Methanol	50-58	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	118-124
30681097-5	2019	For example, PDI-TAB forms fibers of finite length when bulk powder is dispersed in methanol; it shows flexible lengthy 1D fibers when dichloromethane solution of PDI-TAB is injected into methanol solvent.	Methanol	188-196	peptidyl arginine deiminase 1	Homo sapiens	13-16
30681097-5	2019	For example, PDI-TAB forms fibers of finite length when bulk powder is dispersed in methanol; it shows flexible lengthy 1D fibers when dichloromethane solution of PDI-TAB is injected into methanol solvent.	Methanol	188-196	peptidyl arginine deiminase 1	Homo sapiens	163-166
30630617-3	2019	IM-BIM@Sil in a methanol/water (60:40, v/v) solution at 60  C extracted the highest amount of aristolochic acid (16.69 mg/g) compared to the other sorbents examined.	Methanol	16-24	STIL centriolar assembly protein	Homo sapiens	7-10
31191761-0	2019	Evolution of intermetallic GaPd2/SiO2 catalyst and optimization for methanol synthesis at ambient pressure.	Methanol	68-76	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	Homo sapiens	27-32
31191761-1	2019	The CO2 hydrogenation to methanol is efficiently catalyzed at ambient pressure by nanodispersed intermetallic GaPd2/SiO2 catalysts prepared by incipient wetness impregnation.	Methanol	25-33	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	Homo sapiens	110-115
30807953-5	2019	Among them, methanol was selected as the most adequate co-solvent, leading to the complete elimination of CT (100 mg L-1, 24 h) with a moderate unproductive consumption of the oxidant.	Methanol	12-20	immunoglobulin kappa variable 1-16	Homo sapiens	117-120
31193178-1	2019	In the present work, we applied scaled model to calculate surface tension, vapor densities and the critical temperatures of four different models of methanol: namely, H1, J1, J2 and L1 models.	Methanol	149-157	H1.5 linker histone, cluster member	Homo sapiens	167-184
30924601-0	2019	Carbon-Coated and Interfacial-Functionalized Mixed-Phase Mox Ti1-x O2-delta Nanotubes as Highly Active and Durable PtRu Catalyst Support for Methanol Electrooxidation.	Methanol	141-149	monooxygenase DBH like 1	Homo sapiens	57-60
30807922-5	2019	The Turkish aqueous extract exhibited the strongest ABTS scavenging and ferric reducing power while its methanol extract was the most effective acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitor.	Methanol	104-112	cholinesterase	Meleagris gallopavo	176-197
30807922-5	2019	The Turkish aqueous extract exhibited the strongest ABTS scavenging and ferric reducing power while its methanol extract was the most effective acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitor.	Methanol	104-112	cholinesterase	Meleagris gallopavo	199-203
30993276-1	2019	A di-iodo-bridged PdI dimer bearing an N-heterocyclic carbene ligand was made accessible via the reduction of [(IPr)PdI2]2 in basic methanol solution.	Methanol	132-140	peptidyl arginine deiminase 1	Homo sapiens	18-21
30924601-1	2019	A synchronous carbon-coating and interfacial-functionalizing approach is proposed for the fabrication of Mo-doped Mox Ti1-x O2-delta nanotubes (C@IF-MTNTs) under mild hydrothermal reaction with subsequent annealing as advanced catalyst supports for PtRu nanoparticles (NPs) towards methanol electrooxidation.	Methanol	282-290	monooxygenase DBH like 1	Homo sapiens	114-117
30572091-10	2019	Following fractionation of the TC plant material, the ethyl acetate fraction had interesting antioxidant activity and the methanol/water (35%) and hexane fractions had good 15-LOX inhibitory activity.	Methanol	122-130	arachidonate 15-lipoxygenase	Mus musculus	173-179
31002525-4	2019	That is, a polar organic solution of lead halide (PbX2) was impregnated into the MOF pores to give PbX2@MIL-101, which was then subjected to a perovskite-formation reaction with cesium halide (CsX) dissolved in methanol.	Methanol	211-219	PBX homeobox 2	Homo sapiens	50-54
31002525-4	2019	That is, a polar organic solution of lead halide (PbX2) was impregnated into the MOF pores to give PbX2@MIL-101, which was then subjected to a perovskite-formation reaction with cesium halide (CsX) dissolved in methanol.	Methanol	211-219	PBX homeobox 2	Homo sapiens	99-103
30884639-4	2019	TR was dissolved in methanol and directly exposed to atmospheric non-thermal plasma field at 250 W for different durations (10, 20, 40, and 60 min), 40% relative humidity, and 25  C. TR treated with plasma for 40 min showed greatly enhanced inhibitory activities for alpha-glucosidase and alpha-amylase than parent TR.	Methanol	20-28	coagulation factor II thrombin receptor	Homo sapiens	0-2
30955332-4	2019	The MeOH extract exhibited significant inhibition of the major human CYP450 isozymes (CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19).	Methanol	4-8	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	86-92
30955332-4	2019	The MeOH extract exhibited significant inhibition of the major human CYP450 isozymes (CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19).	Methanol	4-8	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	94-100
30955332-4	2019	The MeOH extract exhibited significant inhibition of the major human CYP450 isozymes (CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19).	Methanol	4-8	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	102-108
30955332-4	2019	The MeOH extract exhibited significant inhibition of the major human CYP450 isozymes (CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19).	Methanol	4-8	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	110-116
30955332-4	2019	The MeOH extract exhibited significant inhibition of the major human CYP450 isozymes (CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19).	Methanol	4-8	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	122-129
30942073-4	2019	HO2 and CH3C(O)O2 were formed by Cl-atom reactions with CH3OH and CH3CHO, respectively.	Methanol	56-61	heme oxygenase 2	Homo sapiens	0-3
31015457-2	2019	Herein, we report that the ensemble of Pt single atoms coordinated with oxygen atoms in MIL-101 (Pt1@MIL) induces distinct reaction path to improve selective hydrogenation of CO2 into methanol.	Methanol	184-192	zinc finger protein 77	Homo sapiens	97-104
31015457-4	2019	Moreover, the selectivity for methanol is 90.3% over Pt1@MIL, much higher than that (13.3%) over Ptn@MIL with CO as the major product.	Methanol	30-38	zinc finger protein 77	Homo sapiens	53-60
31015457-4	2019	Moreover, the selectivity for methanol is 90.3% over Pt1@MIL, much higher than that (13.3%) over Ptn@MIL with CO as the major product.	Methanol	30-38	pleiotrophin	Homo sapiens	97-100
31015457-6	2019	The unique reaction path over Pt1@MIL not only lowers the activation energy for the enhanced catalytic activity, but also contributes to the high selectivity for methanol.	Methanol	162-170	zinc finger protein 77	Homo sapiens	30-37
31087923-7	2019	The addition of the radical scavengers methanol and tert-butanol can reduce the removal rates of 2-MIB and GSM.	Methanol	39-47	MIB E3 ubiquitin protein ligase 1	Homo sapiens	99-102
30869870-6	2019	The speed and sensitivity of ERIS coupled to a selected ion flow-drift tube mass spectrometry, SIFDT-MS, is demonstrated by the simultaneous quantification of methanol with H3O+, acetone with NO+, and dimethyl sulfide with O2+  reagent ions in single breath exhalations.	Methanol	159-167	stimulator of interferon response cGAMP interactor 1	Homo sapiens	29-33
30869870-6	2019	The speed and sensitivity of ERIS coupled to a selected ion flow-drift tube mass spectrometry, SIFDT-MS, is demonstrated by the simultaneous quantification of methanol with H3O+, acetone with NO+, and dimethyl sulfide with O2+  reagent ions in single breath exhalations.	Methanol	159-167	H3 clustered histone 15	Homo sapiens	173-176
30708293-9	2019	The prevalence of Methylophilaceae, methanol oxidation genes and denitrification genes were related to high influent methanol and NO3- concentration in the influent wastewater.	Methanol	36-44	NBL1, DAN family BMP antagonist	Homo sapiens	130-133
30708293-9	2019	The prevalence of Methylophilaceae, methanol oxidation genes and denitrification genes were related to high influent methanol and NO3- concentration in the influent wastewater.	Methanol	117-125	NBL1, DAN family BMP antagonist	Homo sapiens	130-133
31037025-0	2019	Anticancer Activity of Methanol Extract of Ficus carica Leaves and Fruits Against Proliferation, Apoptosis, and Necrosis in Huh7it Cells.	Methanol	23-31	MIR7-3 host gene	Homo sapiens	124-128
30682647-2	2019	The HQ-BT showed a weak fluorescence that could be strongly enhanced by coordination with various metal ions such as Al3+, Cd2+, Zn2+ in methanol containing 1% water.	Methanol	137-145	CD2 molecule	Homo sapiens	123-126
30682647-3	2019	Interestingly, the selectivity toward Cd2+ was achieved by increasing water fraction to 30% aqueous methanol solution.	Methanol	100-108	CD2 molecule	Homo sapiens	38-41
30855135-5	2019	The prepared nanowire exhibited excellent electrocatalytic activity toward the methanol electro-oxidation and high sensitivity for monitoring the reduction of 4-nitrothiophenol by recording SERS spectra.	Methanol	79-87	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	190-194
30960420-3	2019	The sinusoidal 1 undergoes reversible structural transformation with helical 2 upon removal and uptake of CH3OH, which was accompanied with the conformation adjustment of the 1,4-pbpa ligand from trans anti-anti to trans syn-anti.	Methanol	106-111	synemin	Homo sapiens	221-224
30940305-6	2019	Implants made from the polymers chitosan and PCL may accelerate the degradation of SRL when these polymers are dissolved in methanol at 50  C. HPLC analysis showed that the implant prepared with PLGA 75:25 did not present degradation products and maintained its appropriate drug content, even when dissolved in methanol and heated to 50  C. Therefore, it represents the most suitable biodegradable polymer for use in implants developed for the treatment of malignant solid tumors.	Methanol	124-132	PHD finger protein 1	Homo sapiens	45-48
30940305-6	2019	Implants made from the polymers chitosan and PCL may accelerate the degradation of SRL when these polymers are dissolved in methanol at 50  C. HPLC analysis showed that the implant prepared with PLGA 75:25 did not present degradation products and maintained its appropriate drug content, even when dissolved in methanol and heated to 50  C. Therefore, it represents the most suitable biodegradable polymer for use in implants developed for the treatment of malignant solid tumors.	Methanol	311-319	PHD finger protein 1	Homo sapiens	45-48
30843903-1	2019	We have theoretically investigated the hydrogen abstraction reactions of H2O, H2S, CH3OH, and CH3SH by the CCl3 radical, which is of interest in atmospheric chemistry research.	Methanol	83-88	C-C motif chemokine ligand 3	Homo sapiens	107-111
30843903-7	2019	This study provides the first theoretical and kinetic determination of the CCl3 rate coefficient for reactions with H2O, H2S, CH3OH, and CH3SH over a large temperature range.	Methanol	126-131	C-C motif chemokine ligand 3	Homo sapiens	75-79
30869514-5	2019	NMR titration studies suggest that only 1:1 complexes of Ln(III) with C2-POPhen formed in CH3OH in the presence of a significant amount of nitrate, while both 1:1 and 2:1 complexes species could form between C2-POPhen and Ln(III) perchlorate in CH3OH without nitrate ions.	Methanol	90-95	complement C2	Homo sapiens	70-79
30869514-6	2019	The stability constants for the complexation of Am(III) and Ln(III) with C2-POPhen in CH3OH were determined by spectrophotometric titrations and the Am(III) complexes are approximately 1 order of magnitude stronger than those of Ln(III), which is consistent with the extraction results.	Methanol	86-91	complement C2	Homo sapiens	73-82
30698189-3	2019	In methanol-HEPES buffer solution (9 : 1, 50 mM HEPES, 0.1 M KCl, pH = 7.5), EGTQ exhibits fluorescence enhancement induced by Zn2+ and Cd2+ with poor selectivity, but BAPTQ did not exhibit a fluorescence response to either metal ion.	Methanol	3-11	CD2 molecule	Homo sapiens	136-139
30777306-0	2019	Methanol Accelerates DMPC Flip-Flop and Transfer: A SANS Study on Lipid Dynamics.	Methanol	0-8	USH1 protein network component sans	Homo sapiens	52-56
30716345-2	2019	This method involves the use of the AOX enzyme that could specifically oxidize methanol, giving rise to equimolar equivalents each of formaldehyde (HCHO) and hydrogen peroxide (H2O2) as the end products.	Methanol	79-87	acyl-CoA oxidase 1	Homo sapiens	36-39
30716345-4	2019	In another set up, the amount of formaldehyde produced as a sequel to the oxidation of methanol by the AOX enzyme was determined by allowing it to react with the acetylacetanilide reagent, after which the volume of the fluorescent product - 3,5-di-N-phenylacetyl-1,4-dihydrolutidine (colorless product; lambdaex/em = 390/470 nm) that was generated was estimated by measuring its emission at 460 nm (excitation wavelength at 360 nm) in a spectrophotometer.	Methanol	87-95	acyl-CoA oxidase 1	Homo sapiens	103-106
30890504-1	2019	OBJECTIVE: To investigate the effects of methanol-ethyl acetate partitioned fractions from Descurainia sophia (MEDS) on the proliferation and apoptosis of human non-small cell lung cancer H1975 cells.	Methanol	41-49	immediate early response 3 interacting protein 1	Homo sapiens	111-115
30890504-12	2019	CONCLUSIONS: The methanol-ethyl acetate partitioned fractions from MEDS show potent anti-tumor activity both in vivo and in vitro, suggesting their value as promising therapeutic agents against lung cancer.	Methanol	17-25	immediate early response 3 interacting protein 1	Homo sapiens	67-71
30627799-2	2019	After gradual addition of Hg2+ in aqueous methanol solution of RTS, a strong orange fluorescence and deep-pink coloration were observed.	Methanol	42-50	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	26-29
31031969-13	2019	However, methanol crude extract has high efficacy to induce apoptosis through caspase-3 activation compared to the other extracts.	Methanol	9-17	caspase 3	Homo sapiens	78-87
30698442-2	2019	Direct oxidative C(sp2)-C(sp3) bond formation was realized with the least-studied PhI(OMe)2 as an oxidant, formed in situ from the reaction between PhIO and MeOH.	Methanol	157-161	Sp2 transcription factor	Homo sapiens	17-22
30627799-2	2019	After gradual addition of Hg2+ in aqueous methanol solution of RTS, a strong orange fluorescence and deep-pink coloration were observed.	Methanol	42-50	enolase superfamily member 1	Homo sapiens	63-66
30675063-6	2019	A methanol-soluble fraction of the small intestinal contents of specific-pathogen-free mice, but not germ-free mice, induced dendrite extension of intestinal CX3CR1+ cells in vitro.	Methanol	2-10	C-X3-C motif chemokine receptor 1	Homo sapiens	158-164
30336303-0	2019	Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund"s complete adjuvant-induced arthritis in rats.	Methanol	45-53	tumor necrosis factor	Rattus norvegicus	96-105
30336214-5	2019	Active chymosin expression was achieved into supernatant with Saccharomyces cerevisiae alpha-mating factor under the control of methanol-inducible AOXI promoter.	Methanol	128-136	chymosin	Bos taurus	7-15
30341979-8	2019	Validation results for the Omnical with methanol combustion were -0.05 +- 0.70% (mean +- SD; n = 31) at the 225 mL min-1 VO2 level and -0.23 +- 0.80% (n = 31) at the 150 mL min-1 VCO2 level.	Methanol	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	115-120
30341979-8	2019	Validation results for the Omnical with methanol combustion were -0.05 +- 0.70% (mean +- SD; n = 31) at the 225 mL min-1 VO2 level and -0.23 +- 0.80% (n = 31) at the 150 mL min-1 VCO2 level.	Methanol	40-48	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
30236674-4	2019	A 40% methanol fraction possessed greatest anti-inflammatory activities in IFN-gamma and LPS treated Raw 264.7 cells (P &lt; 0.05).	Methanol	6-14	interferon gamma	Mus musculus	75-84
30679956-9	2019	To further characterize the benefit of methanol as the carbon source, extra NADH from methanol oxidation was engineered to generate NADPH to improve lysine biosynthesis by expression of the POS5 gene from Saccharomyces cerevisiae, which resulted in a twofold improvement of lysine production.	Methanol	39-47	NADH kinase	Saccharomyces cerevisiae S288C	190-194
30679956-9	2019	To further characterize the benefit of methanol as the carbon source, extra NADH from methanol oxidation was engineered to generate NADPH to improve lysine biosynthesis by expression of the POS5 gene from Saccharomyces cerevisiae, which resulted in a twofold improvement of lysine production.	Methanol	86-94	NADH kinase	Saccharomyces cerevisiae S288C	190-194
30570258-9	2019	The noncanonical 310-helix is missing in the previously solved X-ray structure of tetrameric melittin and the NMR structure of melittin in methanol.	Methanol	139-147	melittin	Apis mellifera	127-135
30740291-3	2019	The L4-based RuCl3   3H2O system corresponded to the best conversion of PhI (96 %) along with 99 % selectivity to the target product of methyl benzoate as well as the good generality to alkoxycarbonylation of different aryl halides (ArX, X=I and Br) with alcohols MeOH, EtOH, i-PrOH and n-BuOH.	Methanol	264-268	glucose-6-phosphate isomerase	Homo sapiens	72-75
32450015-6	2019	All the fungal isolates used in the present study for antifungal activity inhibited their growth when a concentration of 2.27 mg mL-1 of methanol extract was used (minimum inhibitory concentration from < 0.28 to 2.27 mg mL-1).	Methanol	137-145	L1 cell adhesion molecule	Mus musculus	129-133
30646727-6	2019	Finally, in order to describe the interaction of methanol with the metal surface, the SRP32-vdW functional is used, which has been previously developed and tested for CHD3 on Ni(111), Pt(111), and Pt(211) using the Specific Reaction Parameter (SRP) approach.	Methanol	49-57	chromodomain helicase DNA binding protein 3	Homo sapiens	167-171
30428383-4	2019	In this study, N-acetyltransferase from P. pastoris (PpMpr1) was overexpressed for the first time to improve the anti-oxidative stress ability to protect cells from strong ROS damage during the methanol induction phase.	Methanol	194-202	N-acetyltransferase	Saccharomyces cerevisiae S288C	15-34
30195569-12	2019	Some hydrophobic low molecular weight fractions (30%, 70% and 100% MeOH ODS fraction), which were fractionated from BZYQT by ODS column chromatography, showed enhancing or suppressive effects on productions of IL-2, IL-4 or IL-5 in T lymphocytes of Peyer"s patches after oral administration.	Methanol	67-71	interleukin 2	Mus musculus	210-214
30195569-12	2019	Some hydrophobic low molecular weight fractions (30%, 70% and 100% MeOH ODS fraction), which were fractionated from BZYQT by ODS column chromatography, showed enhancing or suppressive effects on productions of IL-2, IL-4 or IL-5 in T lymphocytes of Peyer"s patches after oral administration.	Methanol	67-71	interleukin 4	Mus musculus	216-220
30107237-8	2019	After methanol-induced expression in a bench-top bioreactor, Pichia recombinants carrying four copies of GalA genes reached 3520 U/mL in the supernatant of the culture.	Methanol	6-14	galactosidase alpha	Homo sapiens	105-109
30362641-5	2019	Formation of product ions H ([D-H2 O]+ ) and M ([H-CO]+ ) is associated with the hydroxyl group at C-3 and C-3", whereas product ions N ([D-MeOH]+ ) and O ([N-MeOH]+ ) indicate a methoxyl group at the same positions.	Methanol	140-144	complement C3	Homo sapiens	99-102
30362641-5	2019	Formation of product ions H ([D-H2 O]+ ) and M ([H-CO]+ ) is associated with the hydroxyl group at C-3 and C-3", whereas product ions N ([D-MeOH]+ ) and O ([N-MeOH]+ ) indicate a methoxyl group at the same positions.	Methanol	140-144	complement C3	Homo sapiens	107-110
30362641-5	2019	Formation of product ions H ([D-H2 O]+ ) and M ([H-CO]+ ) is associated with the hydroxyl group at C-3 and C-3", whereas product ions N ([D-MeOH]+ ) and O ([N-MeOH]+ ) indicate a methoxyl group at the same positions.	Methanol	159-163	complement C3	Homo sapiens	99-102
30362641-5	2019	Formation of product ions H ([D-H2 O]+ ) and M ([H-CO]+ ) is associated with the hydroxyl group at C-3 and C-3", whereas product ions N ([D-MeOH]+ ) and O ([N-MeOH]+ ) indicate a methoxyl group at the same positions.	Methanol	159-163	complement C3	Homo sapiens	107-110
32523324-5	2019	In the solid state, receptor 2 interacts with CsF to form a two dimensional coordination polymer in the presence of methanol.	Methanol	116-124	colony stimulating factor 2	Homo sapiens	46-49
32523324-7	2019	Receptor 2 was also found to form a complex with CsF in chloroform/methanol (4/1, v/v) solution, albeit with a different binding mode than is seen in the solid state.	Methanol	67-75	colony stimulating factor 2	Homo sapiens	49-52
30473529-6	2018	The extracts were prepared freshly by dissolving in sterile phosphate saline buffer (PBS) and the healing activity was observed from 2, 4, 8, 12, 24, 36 and 48 h. The bulb, root, stem and anther methanol extracts demonstrated active wound healing activities at 1 mug mL-1at 36 h of treatment.	Methanol	195-203	L1 cell adhesion molecule	Mus musculus	267-271
30246938-6	2018	Fusing Mdh with Hps or Hps-Phi increased the Vmax of methanol oxidation up to 5.8-fold, and enhanced methanol conversion to fructose-6-phosphate up to 1.3-fold.	Methanol	101-109	malate dehydrogenase 2	Homo sapiens	7-10
30336375-7	2018	As for their biological properties, the methanol extract exhibited the best antioxidant effect in the DPPH and CUPRAC assays, and also the highest inhibition against tyrosinase.	Methanol	40-48	tyrosinase	Meleagris gallopavo	166-176
30352377-11	2018	In-vitro AhR activity was highest in the 70% methanol elution with greater activity in North Pacific Gyre-recovered plastic than in virgin plastic and UV-irradiated virgin plastic (toxic equivalency [TEQ] = 1.06 +- 0.54, 0.38 +- 0.07 and 0.71 +- 0.47 ng/L, respectively).	Methanol	45-53	aryl hydrocarbon receptor 1b	Oryzias latipes	9-12
30352377-13	2018	Chemically-determined TEQ analysis for AhR indicated highest activity in the 90% methanol fraction for all leachates, with whole extract in vitro TEQs being 1.47 +- 0.87, 0.03 +- 0.05 and 0.42 +- 0.38 ng/L for North Pacific Gyre-recovered plastic, virgin plastic and UV-irradiated virgin plastic, respectively.	Methanol	81-89	aryl hydrocarbon receptor 1b	Oryzias latipes	39-42
29968299-0	2018	Aldehyde dehydrogenase 2 polymorphism affects the outcome of methanol poisoning in exposed humans.	Methanol	61-69	aldehyde dehydrogenase 2 family member	Homo sapiens	0-24
29968299-1	2018	As the susceptibility of humans to xenobiotics often depends on genetic factors, we assumed that ADH1B and ALDH2 genetic variants may affect susceptibility to the acute methanol exposure.	Methanol	169-177	alcohol dehydrogenase 1B (class I), beta polypeptide	Homo sapiens	97-102
29968299-1	2018	As the susceptibility of humans to xenobiotics often depends on genetic factors, we assumed that ADH1B and ALDH2 genetic variants may affect susceptibility to the acute methanol exposure.	Methanol	169-177	aldehyde dehydrogenase 2 family member	Homo sapiens	107-112
29968299-3	2018	GG homozygotes of ADH1B were more common among methanol-poisoned patients (98%) and among patients with alcoholic liver cirrhosis (98%) than among healthy controls (90%) (P = 0.08 and &lt; 0.001, respectively).	Methanol	47-55	alcohol dehydrogenase 1B (class I), beta polypeptide	Homo sapiens	18-23
29968299-4	2018	Minor C allele carriers of the ALDH2 were significantly more common among methanol-poisoned persons (46%) than among patients with alcoholic liver cirrhosis or healthy controls (31% in both groups, P &lt; 0.05 and 0.025, respectively); the odds ratios were 1.89 (95% CI 1.02-3.52) and 1.94 (1.08-3.48), respectively.	Methanol	74-82	aldehyde dehydrogenase 2 family member	Homo sapiens	31-36
29968299-6	2018	By contrast, the genetic variant of the ALDH2 enzyme seems to specifically affect the susceptibility to methanol in acutely exposed humans and potentially plays a role in the outcome of methanol poisoning.	Methanol	104-112	aldehyde dehydrogenase 2 family member	Homo sapiens	40-45
29968299-6	2018	By contrast, the genetic variant of the ALDH2 enzyme seems to specifically affect the susceptibility to methanol in acutely exposed humans and potentially plays a role in the outcome of methanol poisoning.	Methanol	186-194	aldehyde dehydrogenase 2 family member	Homo sapiens	40-45
30511862-2	2018	Here we report a direct kinetic measurement of the reaction of syn-CH3CHOO (a Criegee intermediate or carbonyl oxide) with methanol at various relative humidity (RH = 0-80%) under near-ambient conditions (298 K, 250-755 Torr).	Methanol	123-131	synemin	Homo sapiens	63-66
30511862-4	2018	The rate coefficient of the corresponding reaction, syn-CH3CHOO + CH3OH + H2O   products, has been determined to be (1.95 +- 0.11) x 10-32 cm6 s-1 at 298 K, with no observable pressure dependence for 250-755 Torr.	Methanol	66-71	synemin	Homo sapiens	52-55
30516203-3	2018	It should be noted that the acidic character of the salicylic acid promotes, in the presence of methanol, the methoxylation of the H2L ligand thereby yielding a hemiacetal H3L", which is able to connect the Ln(iii) ions of two ZnLn dinuclear units forming the Zn2Ln2 tetranuclear complexes 7 and 8.	Methanol	96-104	H3 clustered histone 2	Homo sapiens	172-175
30643530-6	2018	CCl4-treated rats that were given 250 or 500 mg/kg of the methanol extract of E. Japonica leaves, or its ethyl acetate, butanol, or aqueous fractions, had significantly lower levels of biochemical parameters such as alanine aminotransferase, aspartate transaminase, alkaline phosphate, total protein, gamma-glutamyl transferase, and bilirubin levels than those of the CCl4 positive group.	Methanol	58-66	C-C motif chemokine ligand 4	Rattus norvegicus	0-4
30643530-6	2018	CCl4-treated rats that were given 250 or 500 mg/kg of the methanol extract of E. Japonica leaves, or its ethyl acetate, butanol, or aqueous fractions, had significantly lower levels of biochemical parameters such as alanine aminotransferase, aspartate transaminase, alkaline phosphate, total protein, gamma-glutamyl transferase, and bilirubin levels than those of the CCl4 positive group.	Methanol	58-66	C-C motif chemokine ligand 4	Rattus norvegicus	368-372
30558162-2	2018	In this respect, we studied the complexation of CIT and ochratoxin A (OTA) with Al3+ in methanol using absorption and fluorescence spectroscopy.	Methanol	88-96	citron rho-interacting serine/threonine kinase	Homo sapiens	48-51
30246938-6	2018	Fusing Mdh with Hps or Hps-Phi increased the Vmax of methanol oxidation up to 5.8-fold, and enhanced methanol conversion to fructose-6-phosphate up to 1.3-fold.	Methanol	53-61	malate dehydrogenase 2	Homo sapiens	7-10
30242672-11	2018	The production of ROS, caspase-3 activity and depolarized MMP were quite significant in MDA-MB-231 cell line treated with methanol and ethyl acetate extracts.	Methanol	122-130	caspase 3	Homo sapiens	23-32
29733875-3	2018	We measured the acute concentrations and dynamics of lipoxins LxA4 and LxB4 and the interleukins IL-4, IL-5, IL-9, IL-10, and IL-13 in the serum of patients treated with methyl alcohol poisoning and the follow-up concentrations in survivors two years after discharge from the hospital.	Methanol	170-184	interleukin 13	Homo sapiens	126-131
30351077-2	2018	The general reaction between CuCl2 2H2O, LnCl3 6H2O, phenoxH, and NEt3 in a 1:2:2:4 molar ratio, in a solvent mixture comprising MeCN and MeOH, afforded brown crystals of a new family of [Cu3LnCl3(phenox)6(MeOH)3] clusters (Ln = Gd (1), Tb (2), Dy (3)) that possess an unprecedented [Cu3Ln(mu-NO)6]3+ "propeller"-like core.	Methanol	138-142	tetraspanin 2	Homo sapiens	66-70
30351077-2	2018	The general reaction between CuCl2 2H2O, LnCl3 6H2O, phenoxH, and NEt3 in a 1:2:2:4 molar ratio, in a solvent mixture comprising MeCN and MeOH, afforded brown crystals of a new family of [Cu3LnCl3(phenox)6(MeOH)3] clusters (Ln = Gd (1), Tb (2), Dy (3)) that possess an unprecedented [Cu3Ln(mu-NO)6]3+ "propeller"-like core.	Methanol	206-210	tetraspanin 2	Homo sapiens	66-70
30388753-3	2018	(2) Methods: We prepared the MeOH extracts of 107 different crude drugs, and screened their inhibitory effects on URAT1 by measuring the uptake of uric acid by HEK293/PDZK1 cells transiently transfected with URAT1.	Methanol	29-33	solute carrier family 22 member 12	Homo sapiens	114-119
30084121-7	2018	The values of DeltaE are correlated with possible anisotropy of distribution of fac-[CoII (mu-NC)3 (MeOH)3 ] moieties at the external corners of the cube substructure.	Methanol	100-104	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	85-89
30360499-3	2018	In recent work we have also shown that the use of alcohol dehydrogenase enzyme as a component of the anodic section of a direct catalytic methanol (or ethanol) fuel cell significantly improves the performance of a simple DMFC device, making it more suitable to measure ethanol (or methanol) in real samples by this cell.	Methanol	138-146	aldo-keto reductase family 1 member A1	Homo sapiens	50-71
30360499-3	2018	In recent work we have also shown that the use of alcohol dehydrogenase enzyme as a component of the anodic section of a direct catalytic methanol (or ethanol) fuel cell significantly improves the performance of a simple DMFC device, making it more suitable to measure ethanol (or methanol) in real samples by this cell.	Methanol	281-289	aldo-keto reductase family 1 member A1	Homo sapiens	50-71
30215248-0	2018	DFT Provides Insight into the Additive-Free Conversion of Aqueous Methanol to Dihydrogen Catalyzed by [Ru(trop2dad)]: Importance of the (Electronic) Flexibility of the Diazadiene Moiety.	Methanol	66-74	tumor associated calcium signal transducer 2	Homo sapiens	106-111
30627516-1	2018	The methanol extracts of both leaves and fruits (MEL &amp; MEF) of A. marmelos (L.) Correa (family Rutaceae) were analyzed by using analytical method based on liquid chromatography-tandem mass spectrometry (LC/MS/MS).	Methanol	4-12	E74-like factor 4 (ets domain transcription factor)	Mus musculus	59-62
30381729-7	2018	The methanol extract of H. sabdariffa improved spatial memory consolidation in Wistar rats and prevented impairment in spatial memory consolidation by maintaining the ratio of IL-1beta/IL-1ra in the plasma and hippocampus of Wistar rats who experienced overtraining.	Methanol	4-12	interleukin 1 beta	Rattus norvegicus	176-184
30381729-7	2018	The methanol extract of H. sabdariffa improved spatial memory consolidation in Wistar rats and prevented impairment in spatial memory consolidation by maintaining the ratio of IL-1beta/IL-1ra in the plasma and hippocampus of Wistar rats who experienced overtraining.	Methanol	4-12	interleukin 1 receptor antagonist	Rattus norvegicus	185-191
29800742-8	2018	RESULTS: The MeOH extract of I. obliquus reduced cell viability in all lung cancer cell lines tested through induction of apoptosis accompanied by caspase-3 cleavage.	Methanol	13-17	caspase 3	Homo sapiens	147-156
30297654-3	2018	The control experiments showed that the pH-responsive property of the system could be ascribed to the drug components of the solutions, whereas the thermal-, salt- and methanol-sensitive behaviors were attributed to the PDEA constituent of the films.	Methanol	168-176	phosphodiesterase 6A	Homo sapiens	220-224
29860170-4	2018	The factors affecting the c-myb G-quadruplex structures were investigated, such as cations (i.e. K+, NH4+ and Na+) and co-solutes (methanol and polyethylene glycol).	Methanol	131-139	MYB proto-oncogene, transcription factor	Homo sapiens	26-31
30025298-3	2018	The efficient chromatographic separation of CDM and RIF was succeeded using a C18 column (150 mm x 4.6 mm, 5 mum) with gradient elution using a mobile phase composed of 0.01 M phosphoric acid and methanol at a flow rate of 1 mL min-1.	Methanol	196-204	caldesmon 1	Homo sapiens	44-47
29975195-3	2018	Subsequently, through HCl-methanol treatment, we achieved a significant enhancement in electrical conductivity with little damage to the CCNT features.	Methanol	26-34	cyclin T1	Homo sapiens	137-141
30242223-4	2018	The ALSM and ALCM sensor (ALSM and ALCM denotes the devices prepared by coating the ALS and ALC materials with methanol, respectively) fabricated using the sol-gel method and combustion synthesis combined with quasi-MIT exhibit good gas sensing properties to methanol, in contrast with the two devices (ALSW and ALCW denote the devices prepared for coating the ALS and ALC materials with water, respectively) without the use of quasi-MIT.	Methanol	111-119	allantoicase	Homo sapiens	13-16
30242223-4	2018	The ALSM and ALCM sensor (ALSM and ALCM denotes the devices prepared by coating the ALS and ALC materials with methanol, respectively) fabricated using the sol-gel method and combustion synthesis combined with quasi-MIT exhibit good gas sensing properties to methanol, in contrast with the two devices (ALSW and ALCW denote the devices prepared for coating the ALS and ALC materials with water, respectively) without the use of quasi-MIT.	Methanol	111-119	allantoicase	Homo sapiens	35-38
30242223-4	2018	The ALSM and ALCM sensor (ALSM and ALCM denotes the devices prepared by coating the ALS and ALC materials with methanol, respectively) fabricated using the sol-gel method and combustion synthesis combined with quasi-MIT exhibit good gas sensing properties to methanol, in contrast with the two devices (ALSW and ALCW denote the devices prepared for coating the ALS and ALC materials with water, respectively) without the use of quasi-MIT.	Methanol	259-267	allantoicase	Homo sapiens	13-16
30242223-4	2018	The ALSM and ALCM sensor (ALSM and ALCM denotes the devices prepared by coating the ALS and ALC materials with methanol, respectively) fabricated using the sol-gel method and combustion synthesis combined with quasi-MIT exhibit good gas sensing properties to methanol, in contrast with the two devices (ALSW and ALCW denote the devices prepared for coating the ALS and ALC materials with water, respectively) without the use of quasi-MIT.	Methanol	259-267	allantoicase	Homo sapiens	35-38
30025298-3	2018	The efficient chromatographic separation of CDM and RIF was succeeded using a C18 column (150 mm x 4.6 mm, 5 mum) with gradient elution using a mobile phase composed of 0.01 M phosphoric acid and methanol at a flow rate of 1 mL min-1.	Methanol	196-204	ras homolog family member F, filopodia associated	Homo sapiens	52-55
30021348-9	2018	The altered levels of various parameters provoked by CCl4 toxicity restored towards the control level by the methanol extract of P. hydaspidis in a dose dependent manner.	Methanol	109-117	C-C motif chemokine ligand 4	Rattus norvegicus	53-57
29968466-7	2018	Adding one solvating methanol molecule introduces strikingly distinct dynamical behaviors that largely promote the SN2 reaction, a feature which attributes to a differential solute-solvent interaction at the central barrier that more strongly stabilizes the transition state for substitution.	Methanol	21-29	solute carrier family 38 member 5	Homo sapiens	115-118
30043787-4	2018	Based on CP 1, a device FTO/CP 1/RuO2 was constructed, which showed a much enhanced photoresponse with a much larger specific capacity (120.7 C g-1) than the individual CP 1 (&lt;1 C g-1) and RuO2 (10.5 C g-1) when irradiated by visible light in the presence of methanol.	Methanol	262-270	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	24-27
29961188-8	2018	Moreover, the two different methanol extracts and compounds 1-4 decreased IL-6 production in a strong and concentration-dependent manner by the ELISA method.	Methanol	28-36	interleukin 6	Homo sapiens	74-78
29680043-7	2018	For ORAC method, methanol extract showed the best value with 2771 micromolTE/gDE.	Methanol	17-25	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	77-80
30043787-6	2018	As for the FTO/CP 1/RuO2 device, its specific capacity (120.7 C g-1) obtained by the visible light illumination in the presence of methanol was much larger than that (11.5 C g-1) obtained in the dark without methanol, further suggesting the transformation among solar energy, chemical energy and electric energy.	Methanol	131-139	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	11-14
30043787-6	2018	As for the FTO/CP 1/RuO2 device, its specific capacity (120.7 C g-1) obtained by the visible light illumination in the presence of methanol was much larger than that (11.5 C g-1) obtained in the dark without methanol, further suggesting the transformation among solar energy, chemical energy and electric energy.	Methanol	208-216	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	11-14
29730553-4	2018	The SB Cr3+ conjugate in methanol-water (70:30 v/v) allows quantification of Cr3+ ions with limit of detection 0.44 muM and its self-aggregation in high water fraction facilitates extraction of Cr3+ ions with 95% extraction efficiency.	Methanol	25-33	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	7-10
29730553-4	2018	The SB Cr3+ conjugate in methanol-water (70:30 v/v) allows quantification of Cr3+ ions with limit of detection 0.44 muM and its self-aggregation in high water fraction facilitates extraction of Cr3+ ions with 95% extraction efficiency.	Methanol	25-33	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	77-80
29730553-4	2018	The SB Cr3+ conjugate in methanol-water (70:30 v/v) allows quantification of Cr3+ ions with limit of detection 0.44 muM and its self-aggregation in high water fraction facilitates extraction of Cr3+ ions with 95% extraction efficiency.	Methanol	25-33	latexin	Homo sapiens	116-119
29730553-4	2018	The SB Cr3+ conjugate in methanol-water (70:30 v/v) allows quantification of Cr3+ ions with limit of detection 0.44 muM and its self-aggregation in high water fraction facilitates extraction of Cr3+ ions with 95% extraction efficiency.	Methanol	25-33	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	77-80
29953141-1	2018	In the reaction of [RuHClP3] (P = PPh3) with NaOMe in methanol, the product is [RuH2(CO)P3].	Methanol	54-62	protein phosphatase 4 catalytic subunit	Homo sapiens	34-38
29856995-9	2018	In methanol-water phase, CL and CL + CytC mixture form particles of 83.7 +- 9.8 and 71.3 +- 11.6 nm, respectively.	Methanol	3-11	cytochrome c, somatic	Homo sapiens	37-41
29951737-8	2018	Bacterial carboxylesterases pnbA1 and pnbA2 mimic hCE1 and not hCE2 in its reaction pathways hydrolysing cocaine into benzoylecgonine and methanol rather than ecgonine methyl ester and benzoic acid.	Methanol	138-146	carboxylesterase 1	Homo sapiens	10-27
29951737-8	2018	Bacterial carboxylesterases pnbA1 and pnbA2 mimic hCE1 and not hCE2 in its reaction pathways hydrolysing cocaine into benzoylecgonine and methanol rather than ecgonine methyl ester and benzoic acid.	Methanol	138-146	carboxylesterase 1	Homo sapiens	50-54
29939738-1	2018	The reaction of methanol (CH3OH) with atomic nitrogen was studied considering three elementary reactions, the hydrogen abstractions from the hydroxyl or methyl groups (R1 and R3, respectively) and the C-O bond break (R2).	Methanol	16-24	CD1b molecule	Homo sapiens	168-177
29939738-1	2018	The reaction of methanol (CH3OH) with atomic nitrogen was studied considering three elementary reactions, the hydrogen abstractions from the hydroxyl or methyl groups (R1 and R3, respectively) and the C-O bond break (R2).	Methanol	26-31	CD1b molecule	Homo sapiens	168-177
29775725-6	2018	MATERIALS AND METHODS: Recent study by our research group has observed potent anti-HCV NS3 protease activity of methanol and acetone extracts of N. alba.	Methanol	112-120	KRAS proto-oncogene, GTPase	Homo sapiens	87-90
30008816-1	2018	The present study aimed to investigate the effect of alkaloids and carbinol extracts from lily on the proliferation of SGC-7901 cells, as well as the underlying mechanism.	Methanol	67-75	sarcoglycan beta	Homo sapiens	119-122
30008816-7	2018	Treatment with alkaloid or carbinol extracts deteriorated the morphology of SGC-7901 cells in a dose-dependent manner.	Methanol	27-35	sarcoglycan beta	Homo sapiens	76-79
30008816-8	2018	Alkaloid and carbinol extracts arrested SGC-7901 cells in the G2/M phase, and induced apoptosis in a dose-dependent manner.	Methanol	13-21	sarcoglycan beta	Homo sapiens	40-43
30008816-9	2018	Alkaloid and carbinol extracts enhanced caspase-3, and Fas expression, but reduced FasL expression in SGC-7901 cells.	Methanol	13-21	caspase 3	Homo sapiens	40-49
30008816-9	2018	Alkaloid and carbinol extracts enhanced caspase-3, and Fas expression, but reduced FasL expression in SGC-7901 cells.	Methanol	13-21	Fas ligand	Homo sapiens	83-87
30008816-9	2018	Alkaloid and carbinol extracts enhanced caspase-3, and Fas expression, but reduced FasL expression in SGC-7901 cells.	Methanol	13-21	sarcoglycan beta	Homo sapiens	102-105
30008816-10	2018	The present study demonstrated that alkaloids and carbinol extracts from lily inhibited the proliferation of gastric carcinoma SGC-7901 cells by arresting cells in the G2/M phase.	Methanol	50-58	sarcoglycan beta	Homo sapiens	127-130
29596989-3	2018	The following describes the optimal process conditions for the recombinant engineering of a strain expressing a recombinant Ap (rAp) in a triangular flask: inoculum concentration OD600 value 20.0 in 40 mL working volume (in 500 mL flasks), methanol addition (1.0%; volume ratio), 0.02% biotin solution (60 muL), and YNB primary concentration (13.0 g/L).	Methanol	240-248	LDL receptor related protein associated protein 1	Rattus norvegicus	124-126
29596989-3	2018	The following describes the optimal process conditions for the recombinant engineering of a strain expressing a recombinant Ap (rAp) in a triangular flask: inoculum concentration OD600 value 20.0 in 40 mL working volume (in 500 mL flasks), methanol addition (1.0%; volume ratio), 0.02% biotin solution (60 muL), and YNB primary concentration (13.0 g/L).	Methanol	240-248	LDL receptor related protein associated protein 1	Rattus norvegicus	128-131
29911863-4	2018	Photocatalytic experiments demonstrate that this Cu(I)-MOF exhibits high reactivity for reduction of Cr(VI) in water, with 95% Cr(VI) converting to Cr(III) in 10 min by using MeOH as scavenger under visible-light illumination.	Methanol	175-179	lysine acetyltransferase 8	Homo sapiens	55-58
29601646-6	2018	Analytical separation was performed on a C18 analytical column with different ratios of MeCN-TEAP buffer and MeOH-TEAP buffer (v/v) adjusted to pH 7.5 as mobile phase at a flow rate of 0.7 mL min-1 .	Methanol	109-113	tumor protein p53 inducible nuclear protein 1	Homo sapiens	114-118
29637614-4	2018	As a result of optimization studies, the analysis was carried out using Lux Cellulose-3, methanol as a mobile phase at a flow rate of 1 mL min-1 , and the detection wavelength was arranged to 230 nm.	Methanol	89-97	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
29876547-3	2018	Significantly, the PtPb NP with the new structure shows superior catalytic activity towards the methanol oxidation reaction (MOR).	Methanol	96-104	protein tyrosine phosphatase receptor type B	Homo sapiens	19-23
29771540-1	2018	An ab initio and direct dynamic study of the reactions of CH3O2 + CH3OH and CH3O2 + CH2OH has been carried out over the temperature range of 300-1500 K. All stationary points were calculated at the MP2/aug-cc-pVTZ level of theory for CH3O2 + CH3OH or at the M06-2X/MG3S level of theory for CH3O2 + CH2OH and identified for the local minimum.	Methanol	66-71	tryptase pseudogene 1	Homo sapiens	198-201
29896842-5	2018	The results demonstrated that PME had slight but significant activity in the tomato fruit during in vitro oral processing generating methanol as a function of oral processing time, which was further evidenced using immunolabeling techniques to detect methylated pectin epitopes.	Methanol	133-141	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	30-33
29774354-3	2018	Chromism was demonstrated to stem from the quantitative desorption of methanol from 1-pink to produce [Co(ii)(dabco)(NCS)2] dabco (1-blue(c)) by thermogravimetric (TG) and temperature controlled gas chromatography-mass spectrometry (GC-MS) analyses, and powder X-ray diffraction (XRD) analysis suggests that the transformation between the crystalline phases of 1-pink and 1-blue(c) occurred with similar lattice parameters.	Methanol	70-78	cytosolic thiouridylase subunit 2	Homo sapiens	117-122
29588201-8	2018	Among the components of BTS, the methanol extracts of Platycodi Radix and Zingiberis Rhizoma contribute but the extracts of Ephedrae Herba and Rhei Rhizoma counteract the suppressive effect of BTS on cholesterol uptake into Caco-2 cells.	Methanol	33-41	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	24-27
29977314-0	2018	ROS-Mediated Mitochondrial Pathway is Required for Manilkara Zapota (L.) P. Royen Leaf Methanol Extract Inducing Apoptosis in the Modulation of Caspase Activation and EGFR/NF-kappaB Activities of HeLa Human Cervical Cancer Cells.	Methanol	87-95	epidermal growth factor receptor	Homo sapiens	167-171
29977314-0	2018	ROS-Mediated Mitochondrial Pathway is Required for Manilkara Zapota (L.) P. Royen Leaf Methanol Extract Inducing Apoptosis in the Modulation of Caspase Activation and EGFR/NF-kappaB Activities of HeLa Human Cervical Cancer Cells.	Methanol	87-95	nuclear factor kappa B subunit 1	Homo sapiens	172-181
29977314-10	2018	Overall analyses revealed that Manilkara zapota leaf methanol extract can inhibit the viability of HeLa cells, induce mitochondrial ROS generation, and inhibit nuclear factor-kappa B (NF-kappaB) and epidermal growth factor receptor (EGFR) transcriptional activities.	Methanol	53-61	nuclear factor kappa B subunit 1	Homo sapiens	160-182
29977314-10	2018	Overall analyses revealed that Manilkara zapota leaf methanol extract can inhibit the viability of HeLa cells, induce mitochondrial ROS generation, and inhibit nuclear factor-kappa B (NF-kappaB) and epidermal growth factor receptor (EGFR) transcriptional activities.	Methanol	53-61	nuclear factor kappa B subunit 1	Homo sapiens	184-193
29977314-10	2018	Overall analyses revealed that Manilkara zapota leaf methanol extract can inhibit the viability of HeLa cells, induce mitochondrial ROS generation, and inhibit nuclear factor-kappa B (NF-kappaB) and epidermal growth factor receptor (EGFR) transcriptional activities.	Methanol	53-61	epidermal growth factor receptor	Homo sapiens	199-231
29977314-10	2018	Overall analyses revealed that Manilkara zapota leaf methanol extract can inhibit the viability of HeLa cells, induce mitochondrial ROS generation, and inhibit nuclear factor-kappa B (NF-kappaB) and epidermal growth factor receptor (EGFR) transcriptional activities.	Methanol	53-61	epidermal growth factor receptor	Homo sapiens	233-237
29532855-3	2018	In the present study, the biological effects of an RA methanol extract (RAME) on inflammation were investigated in tumor necrosis factor-alpha (TNF-alpha)/interferon-gamma (IFN-gamma)-stimulated human keratinocytes.	Methanol	54-62	interferon gamma	Homo sapiens	173-182
28849680-0	2018	Evaluation of the effect of erythropoietin + corticosteroid versus corticosteroid alone in methanol-induced optic nerve neuropathy.	Methanol	91-99	erythropoietin	Homo sapiens	28-42
28849680-2	2018	Erythropoietin (EPO) has recently been introduced as a good therapeutic option in methanol-induced optic neuropathy.	Methanol	82-90	erythropoietin	Homo sapiens	0-14
28849680-2	2018	Erythropoietin (EPO) has recently been introduced as a good therapeutic option in methanol-induced optic neuropathy.	Methanol	82-90	erythropoietin	Homo sapiens	16-19
28849680-3	2018	The aim of the current study was to evaluate the efficacy of EPO in improvement of the visual disturbances in methanol-intoxicated patients.	Methanol	110-118	erythropoietin	Homo sapiens	61-64
28849680-10	2018	CONCLUSIONS: Protective effect of EPO on methanol-induced optic nerve may be strong at the beginning of the intervention but is probably transient.	Methanol	41-49	erythropoietin	Homo sapiens	34-37
29432855-0	2018	Suppression of lung inflammation by the methanol extract of Spilanthes acmella Murray is related to differential regulation of NF-kappaB and Nrf2.	Methanol	40-48	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	127-136
29300238-0	2018	Erythropoietin in Treatment of Methanol Optic Neuropathy.	Methanol	31-39	erythropoietin	Homo sapiens	0-14
29300238-2	2018	In this study, we evaluated the potential neuroprotective effect of erythropoietin (EPO) on visual acuity (VA) in patients with methanol optic neuropathy.	Methanol	128-136	erythropoietin	Homo sapiens	68-82
29300238-2	2018	In this study, we evaluated the potential neuroprotective effect of erythropoietin (EPO) on visual acuity (VA) in patients with methanol optic neuropathy.	Methanol	128-136	erythropoietin	Homo sapiens	84-87
29300238-11	2018	The mean time interval between methanol ingestion and treatment with intravenous EPO was 9.1 days (+-5.56 days).	Methanol	31-39	erythropoietin	Homo sapiens	81-84
29300238-17	2018	CONCLUSIONS: Intravenous EPO appears to improve VA in patients with methanol optic neuropathy and may represent a promising treatment for this disorder.	Methanol	68-76	erythropoietin	Homo sapiens	25-28
28637123-7	2018	Here, we report the screening of five plant extracts against swarming motility of P. aeruginosa and show that methanol extracts of Alpinia officinarum and Cinnamomum tamala inhibit swarming motility at 5 mug mL-1 without inhibiting its growth.	Methanol	110-118	L1 cell adhesion molecule	Mus musculus	208-212
29853932-2	2018	This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of recombinant human growth hormone (r-hGH).	Methanol	122-130	growth hormone 1	Homo sapiens	168-182
29945385-5	2018	When ECH was stored in methanol, two primary products (P1 and P2) could be observed in HPLC chromatogram.	Methanol	23-31	crystallin gamma F, pseudogene	Homo sapiens	55-64
30090308-9	2018	In MeOH/CHCl3 (1/1 vol) both compounds selectively bind cyanide to form the corresponding mu(1,2) chelate complexes with a B-C[triple bond, length as m-dash]N-B bridge at their cores.	Methanol	3-7	glutathione S-transferase mu 1	Homo sapiens	90-96
32254242-3	2018	The new probe RV-1 showed a very strong fluorescence emission at around 655 nm, with a 48.5-fold enhancement of fluorescence intensity from methanol to 99% glycerol.	Methanol	140-148	Friend virus susceptibility 1	Mus musculus	14-18
29432855-0	2018	Suppression of lung inflammation by the methanol extract of Spilanthes acmella Murray is related to differential regulation of NF-kappaB and Nrf2.	Methanol	40-48	nuclear factor, erythroid derived 2, like 2	Mus musculus	141-145
29589631-4	2018	In alloxan-induced diabetic mice, the oral administration of a methanol extract (500 mg per kg bw) attenuated the elevated levels of serum alanine aminotransferase (ALA), aspartate aminotransferase (AST), and alkaline phosphatase activities, and urea, uric acid, and creatinine.	Methanol	63-71	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	171-197
29765815-5	2018	Methanol extracts of Nigella sativa, Psidium guajava and Syzygium aromaticum were the most effective among all 20 plant samples and have potent inhibitory activity against both dental caries pathogens with minimum inhibitory concentration of 0.2 mg mL- 1.	Methanol	0-8	L1 cell adhesion molecule	Mus musculus	249-254
29765815-6	2018	N. sativa seed methanol extract was more effective with 22.3 mm zone of inhibition at 0.2 mg mL- 1 against S. mutans (MTCC 497), while L. acidophilus (MTCC 10307) was more sensitive to S. aromaticum bud methanol extract at 11.3 mm zone of inhibition at concentration 0.1 mg mL- 1.	Methanol	15-23	L1 cell adhesion molecule	Mus musculus	93-98
29765815-6	2018	N. sativa seed methanol extract was more effective with 22.3 mm zone of inhibition at 0.2 mg mL- 1 against S. mutans (MTCC 497), while L. acidophilus (MTCC 10307) was more sensitive to S. aromaticum bud methanol extract at 11.3 mm zone of inhibition at concentration 0.1 mg mL- 1.	Methanol	15-23	L1 cell adhesion molecule	Mus musculus	274-279
29589631-4	2018	In alloxan-induced diabetic mice, the oral administration of a methanol extract (500 mg per kg bw) attenuated the elevated levels of serum alanine aminotransferase (ALA), aspartate aminotransferase (AST), and alkaline phosphatase activities, and urea, uric acid, and creatinine.	Methanol	63-71	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	199-202
29278988-6	2018	The methanol extract from the stem bark was significantly cytotoxic to MCF-7 and Caco-2 cell lines (p &lt; 0.05) in a concentration-dependent manner with IC50 values of 6.6 and 8.1 microg mL-1, respectively relative to the control.	Methanol	4-12	L1 cell adhesion molecule	Mus musculus	188-192
29611701-4	2018	The optimized Fe,Co,N-CNP(0.3) (Fe/Co molar ratio of 0.3 in Fe,Co-ZIF) electrocatalyst exhibited a highly promising activity for oxygen reduction reaction (ORR) with a positive half-wave potential ( E1/2) of 0.875 V (29 mV higher than that of the commercial Pt/C), excellent methanol tolerance, and electrochemical stability in the alkaline electrolyte.	Methanol	275-283	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	22-25
29611701-5	2018	Also, Fe,Co,N-CNP(0.3) presents comparable ORR catalytic activity as Pt/C in the acidic electrolyte with E1/2 of 0.764 V and superior methanol tolerance and electrochemical stability.	Methanol	134-142	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	14-17
29315883-2	2018	The temperature at which the high and low spin states are present in equal proportions is T1/2 =140 K. Single crystal, variable-temperature optical spectroscopy of [FeII (tame)2 ]Cl2  MeOH is consistent with this change in electronic ground state.	Methanol	184-188	spindlin 1	Homo sapiens	42-46
29616360-1	2018	This study introduces a novel titanium dioxide carbon nanofiber (TiO2-CNF) support for anodic catalyst in direct methanol fuel cell.	Methanol	113-121	NPHS1 adhesion molecule, nephrin	Homo sapiens	70-73
29413354-2	2018	Then all these three ligands have been used to prepare Pb(II) complexes by reaction with lead(II) acetate tri-hydrate in methanol.	Methanol	121-129	submaxillary gland androgen regulated protein 3B	Homo sapiens	55-61
29725354-0	2018	Src Is a Prime Target Inhibited by Celtis choseniana Methanol Extract in Its Anti-Inflammatory Action.	Methanol	53-61	Rous sarcoma oncogene	Mus musculus	0-3
29521389-1	2018	A greener synthesis of Cu-MOF-74 was obtained, for the first time, in methanol as the unique solvent and at room temperature.	Methanol	70-78	lysine acetyltransferase 8	Homo sapiens	26-29
29421032-7	2018	Western blotting and Mass Spectrometry demonstrated that recombinant human KGF (rhKGF) was correctly expressed after methanol induction and secreted into the media.	Methanol	117-125	fibroblast growth factor 7	Homo sapiens	75-78
30087758-0	2018	Effect of Ferula persica plant methanol extract on the level of Cox-2 in induced squamous cell carcinoma (SCC) in rat tongue.	Methanol	31-39	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	64-69
30087758-5	2018	In this study , the effect of Ferula persica plant methanol extraction on Cox-2 levels in SCC induced rat tongue is conducted in vivo.	Methanol	51-59	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	74-79
29363716-0	2018	Apoptosis induced by methanol extract of Potentilla discolor in human mucoepidermoid carcinoma cells through STAT3/PUMA signaling axis.	Methanol	21-29	signal transducer and activator of transcription 3	Homo sapiens	109-114
28918219-1	2018	The optical properties of a novel chemosensor for cyanide anions based on a symmetric bis(salamo)-type ligand (H3L) were investigated by UV-Vis and fluorescence spectroscopy in MeOH/H2O (1:1 v/v) solution.	Methanol	177-181	H3 clustered histone 2	Homo sapiens	111-114
29469909-3	2018	Here, Cu-rich PtCu octahedral alloys achieved by a composition-driven shape evolution route have been used as outstanding bifunctional electrocatalysts for both methanol oxidation (MOR) and oxygen reduction reaction (ORR) in an acid medium.	Methanol	161-169	opioid receptor mu 1	Homo sapiens	181-184
29341380-2	2018	A Mott-Schottky catalyst composed of Ni nanoparticles and tailorable nitrogen-doped carbon-foam (Ni/NCF) and thus tunable adsorption energy is presented for highly efficient and selective dehydrogenation of gas-phase methanol to hydrogen and CO even under relatively high weight hourly space velocities (WHSV).	Methanol	217-225	neutrophil cytosolic factor 4	Homo sapiens	100-103
29341380-3	2018	Both theoretical and experimental results reveal the key role of the rectifying contact at the Ni/NCF boundaries in tailoring the electron density of Ni species and enhancing the absorption energies of methanol molecules, which leads to a remarkably high turnover frequency (TOF) value (356 mol methanol mol-1  Ni h-1 at 350  C), outpacing previously reported bench-marked transition-metal catalysts 10-fold.	Methanol	202-210	neutrophil cytosolic factor 4	Homo sapiens	98-101
29341380-3	2018	Both theoretical and experimental results reveal the key role of the rectifying contact at the Ni/NCF boundaries in tailoring the electron density of Ni species and enhancing the absorption energies of methanol molecules, which leads to a remarkably high turnover frequency (TOF) value (356 mol methanol mol-1  Ni h-1 at 350  C), outpacing previously reported bench-marked transition-metal catalysts 10-fold.	Methanol	295-303	neutrophil cytosolic factor 4	Homo sapiens	98-101
29328440-5	2018	In the present study, the anti-inflammatory effects of the methanol extract of G. speciosa (MGS) were investigated in murine macrophages by measuring the production of inflammatory mediators and the underlying mechanisms of action by performing immunoblotting analysis of proteins that are potentially involved.	Methanol	59-67	glycogen synthase 1, muscle	Mus musculus	92-95
29134712-8	2018	This is a typical case of degradation where co-solvents acetonitrile-water (50:50, v/v) and methanol-water (50:50, v/v) react with CAN under acid hydrolytic conditions leading to the formation of pseudo-DPs, DP3 and DP4, respectively.	Methanol	92-100	APC regulator of WNT signaling pathway	Homo sapiens	208-211
29134712-8	2018	This is a typical case of degradation where co-solvents acetonitrile-water (50:50, v/v) and methanol-water (50:50, v/v) react with CAN under acid hydrolytic conditions leading to the formation of pseudo-DPs, DP3 and DP4, respectively.	Methanol	92-100	transcription factor Dp family member 3	Homo sapiens	216-219
29266442-1	2018	Two novel reaction pathways were tested to synthesize the linear alpha,omega-C10 -diester exclusively from three basic reagents: 1,3-butadiene, carbon monoxide and methanol.	Methanol	164-172	homeobox C10	Homo sapiens	77-80
29266442-2	2018	Therefore, carboxytelomerization of 1,3-butadiene and methanol was merged with methoxycarbonylation in two different ways to obtain highly linear C10 -diester.	Methanol	54-62	homeobox C10	Homo sapiens	146-149
29298388-5	2018	More importantly, the Fe@Aza-PON displayed outstanding stability (zero current loss even after 100 000 cycles) and tolerance against contamination (methanol and CO poisoning).	Methanol	148-156	paraoxonase 1	Homo sapiens	29-32
30156068-3	2018	The recombinant plasmid pPIC9K-LYZL4 was constructed and its expression induced with methanol after transformed into competent Pichia pastoris GS115.	Methanol	85-93	lysozyme-like 4	Rattus norvegicus	31-36
29434527-9	2018	Results: Positive staining was observed following methanol fixation for claudin-1 and ZO-1 tight junction proteins but no staining was detected for occludin in 16HBE14o- cells.	Methanol	50-58	claudin 1	Homo sapiens	72-81
29434527-9	2018	Results: Positive staining was observed following methanol fixation for claudin-1 and ZO-1 tight junction proteins but no staining was detected for occludin in 16HBE14o- cells.	Methanol	50-58	tight junction protein 1	Homo sapiens	86-90
29434527-10	2018	Combinatorial fixation with methanol and acetone also produced consistent positive staining for both occludin and ZO-1 tight junction proteins in these cells.	Methanol	28-36	occludin	Homo sapiens	101-109
29434527-10	2018	Combinatorial fixation with methanol and acetone also produced consistent positive staining for both occludin and ZO-1 tight junction proteins in these cells.	Methanol	28-36	tight junction protein 1	Homo sapiens	114-118
29434527-11	2018	When assessed using primary cells cultured at air-liquid interface, similar positive staining for claudin-1 and ZO-1 was observed following methanol fixation, while similar positive staining for occludin and ZO-1 was observed following the same combinatorial fixation with methanol and acetone.	Methanol	140-148	claudin 1	Homo sapiens	98-107
29206917-10	2018	GRP78 became detectable only after a brief exposure of cells to ice-cold methanol.	Methanol	73-81	heat shock protein family A (Hsp70) member 5	Homo sapiens	0-5
29152897-4	2018	After incubation with alpha-glucosidase in vitro, the methanol extract with an IC50 value of 0.19 mg/mL exhibited significant inhibitory activity.	Methanol	54-62	sucrase-isomaltase	Homo sapiens	22-39
29105714-4	2018	Addition of methanol vapor quenched both the visible and NIR emissions by the hole-consuming reaction of methanol.	Methanol	12-20	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	57-60
29105714-4	2018	Addition of methanol vapor quenched both the visible and NIR emissions by the hole-consuming reaction of methanol.	Methanol	105-113	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	57-60
30674768-7	2018	The effects of methanol extract on cardiomyocyte apoptosis induced by doxorubicin using H9c2 cells were evaluated by MTT assay and Annexin V-FITC/PI staining assay.	Methanol	15-23	annexin A5	Rattus norvegicus	131-140
29172489-4	2018	In addition to reaction with O2, cis-[Pd(IPr)2(eta2-O2)] reacts at low temperature with H2O in methanol/ether solution to form trans-[Pd(IPr)2(OH)(OOH)].	Methanol	95-103	DNA polymerase iota	Homo sapiens	47-54
29968547-5	2018	In addition, methanol neurotoxicity in hippocampus caused a significant increase in cell death (caspase3+ cells) and cell edema at 7 and 28 days, which were significantly decreased by LED therapy.	Methanol	13-21	caspase 3	Rattus norvegicus	96-104
29968547-7	2018	Finally, methanol neurotoxicity caused a significant decrease in the number of brain-derived neurotrophic factor (BDNF+) cells, but also circulating serum BDNF, at 7 and 28 days, compared to controls, which were significantly increased by LED therapy.	Methanol	9-17	brain-derived neurotrophic factor	Rattus norvegicus	79-112
29968547-7	2018	Finally, methanol neurotoxicity caused a significant decrease in the number of brain-derived neurotrophic factor (BDNF+) cells, but also circulating serum BDNF, at 7 and 28 days, compared to controls, which were significantly increased by LED therapy.	Methanol	9-17	brain-derived neurotrophic factor	Rattus norvegicus	114-118
29968547-7	2018	Finally, methanol neurotoxicity caused a significant decrease in the number of brain-derived neurotrophic factor (BDNF+) cells, but also circulating serum BDNF, at 7 and 28 days, compared to controls, which were significantly increased by LED therapy.	Methanol	9-17	brain-derived neurotrophic factor	Rattus norvegicus	155-159
29604909-6	2018	Methanol extracts of F. pinicola and I. obliquus were less effective, with proliferation-inhibiting capacities at concentrations below 70 and 200 mug   mL-1, respectively.	Methanol	0-8	L1 cell adhesion molecule	Mus musculus	152-156
29165911-5	2018	The defects and interfaces on PtPb nanoplates, controlled by the fluence of incident C+ ions, make them exhibit the volcano-like electrocatalytic activity for methanol oxidation reaction (MOR), ethanol oxidation reaction (EOR), and oxygen reduction reaction (ORR) as a function of ion irradiation fluence.	Methanol	159-167	protein tyrosine phosphatase receptor type B	Homo sapiens	30-34
30806229-9	2018	The F. pinicola methanol extract was found to have varying degrees of antifungal effects against the pathogenic fungi tested (minimum inhibitory concentration from 23.63 to 66.81 mug   mL-1).	Methanol	16-24	L1 cell adhesion molecule	Mus musculus	185-189
28929601-3	2018	Chlorobenzoyl cations can be efficiently converted into cholorophenol radical cations by the reaction with methanol in the ion trap analyzer under CI-MSn conditions.	Methanol	107-115	moesin	Homo sapiens	150-153
29958061-6	2018	Induction time, methanol concentration and initial pH were optimized for obtaining high levels of hPinX1 protein production.	Methanol	16-24	PIN2 (TERF1) interacting telomerase inhibitor 1	Homo sapiens	98-104
29148819-5	2017	We reveal a multistep ESPT reaction from diF to methanol with an initial proton dissociation on the ~600 fs time scale that forms a charge-separated state, stabilized by solvation, and followed by a diffusion-controlled proton transfer on the ~350 ps time scale.	Methanol	48-56	tumor necrosis factor	Homo sapiens	41-44
29246106-4	2017	RESULTS: Thrombin-induced platelet aggregation was significantly augmented by methanol at pharmacological concentrations (0.5-2%) in a concentration-dependent manner.	Methanol	78-86	coagulation factor II, thrombin	Homo sapiens	9-17
29071175-6	2017	Results of the in vitro ARI activity against partially purified bovine lens aldose reductase showed that methanol extract of CGFs exhibited 96.6% ARI activity at IC50 value 6.12 microg/mL followed by water extract 89.1% with the IC50 value 6.50 microg/mL.	Methanol	105-113	aldose reductase	Bos taurus	76-92
29017144-4	2017	An elevated plus maze test was carried ought where the methanol (AtM), dicloromethane (AtD) and hexanic (AtH) extracts presented anxiolytic activity in mice when exposed to the test.	Methanol	55-63	Serine/Threonine-kinase ATM-like protein	Arabidopsis thaliana	65-68
29114330-4	2017	Furthermore, a strategy for the hydrolysis of the BF2 group has been established using aqueous methanol and sodium hydroxide or triethylamine.	Methanol	95-103	forkhead box G1	Homo sapiens	50-53
27925497-9	2017	RESULTS: The methanol extract from D. harra flowers and its flavonoid-enriched fraction inhibit GSK3beta in PAR2-stimulated IEC6 cells.	Methanol	13-21	glycogen synthase kinase 3 beta	Homo sapiens	96-104
29052339-3	2017	For a cobalt complex of the tetradentate methanol-bridged bispyridyl-bipyridyl complex [CoII Br(tpy)]Br, a detailed mechanistic picture is obtained by combining electrochemistry, spectroscopy, and photocatalysis.	Methanol	41-49	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	88-92
29200848-2	2017	The extract used was n-hexane partition of the methanol extract of Piper cabralanum (PCA-HEX).	Methanol	47-55	hematopoietically expressed homeobox	Homo sapiens	89-92
29250408-2	2017	Each CoII ion is coordinated by two pyridine N atoms from two bridging L ligands, two O atoms from methanol mol-ecules and two chloride anions, all inversion-related.	Methanol	99-107	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	5-9
29185908-2	2017	In the present study, the growth inhibition kinetics of recombinant P. pastoris expressing human interferon gamma was studied under different initial substrate concentrations of gluconate (10-100 g L-1) and methanol (2-50 g L-1) in modified FM22 medium.	Methanol	207-215	interferon gamma	Homo sapiens	97-113
29185908-3	2017	The highest specific growth rate of 0.0206 and 0.019 hr-1 was observed at 60 g L-1 of gluconate and 10 g L-1 of methanol, respectively.	Methanol	112-120	L1 cell adhesion molecule	Homo sapiens	79-82
29185908-3	2017	The highest specific growth rate of 0.0206 and 0.019 hr-1 was observed at 60 g L-1 of gluconate and 10 g L-1 of methanol, respectively.	Methanol	112-120	L1 cell adhesion molecule	Homo sapiens	105-108
28632338-1	2017	The relevance of the -CF2 H moiety has attracted considerable attention from organic synthetic and medicinal chemistry communities, because this group can act as a more lipophilic isostere of the carbinol, thiol, hydroxamic acid, or amide groups.	Methanol	196-204	ATPase H+ transporting accessory protein 1	Homo sapiens	22-25
28964007-1	2017	Infrared plus vacuum ultraviolet (IR + VUV) photoionization vibrational spectroscopy of 2-butanone/methanol clusters [MEK (MeOH)n, n = 1-4] is performed to explore structures associated with hydrogen bonding of MeOH molecules to the carbonyl functional group of the ketone.	Methanol	99-107	mitogen-activated protein kinase kinase 7	Homo sapiens	118-121
29044328-4	2018	The cascade reaction to reduce carbon dioxide into methanol has been explored by the authors, using, sequentially, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FalDH), and formate dehydrogenase (FDH), powered by NAD+/NADH and glutamate dehydrogenase (GDH) as the co-enzyme regenerating system.	Methanol	51-59	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	138-141
29044328-4	2018	The cascade reaction to reduce carbon dioxide into methanol has been explored by the authors, using, sequentially, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FalDH), and formate dehydrogenase (FDH), powered by NAD+/NADH and glutamate dehydrogenase (GDH) as the co-enzyme regenerating system.	Methanol	51-59	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	144-170
29044328-4	2018	The cascade reaction to reduce carbon dioxide into methanol has been explored by the authors, using, sequentially, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FalDH), and formate dehydrogenase (FDH), powered by NAD+/NADH and glutamate dehydrogenase (GDH) as the co-enzyme regenerating system.	Methanol	51-59	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	172-177
29044328-4	2018	The cascade reaction to reduce carbon dioxide into methanol has been explored by the authors, using, sequentially, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FalDH), and formate dehydrogenase (FDH), powered by NAD+/NADH and glutamate dehydrogenase (GDH) as the co-enzyme regenerating system.	Methanol	51-59	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	184-205
29044328-4	2018	The cascade reaction to reduce carbon dioxide into methanol has been explored by the authors, using, sequentially, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FalDH), and formate dehydrogenase (FDH), powered by NAD+/NADH and glutamate dehydrogenase (GDH) as the co-enzyme regenerating system.	Methanol	51-59	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	207-210
28827003-6	2017	All tested extracts and molecules also induced release of IFN-gamma remarkably ranging between 5031.95+-0.05pg/mL, P&lt;0.001 for MeOH extract (6mug) and 5877.08+-0.06pg/mL, P&lt;0.001 for compound 1 (6mug) compared to QS-21 (6mug, 5924.87+-0.1pg/mL, P&lt;0.001).	Methanol	130-134	interferon gamma	Homo sapiens	58-67
29552064-0	2017	Evaluation of Sorbitol-Methanol Co-Feeding Strategy on Production of Recombinant Human Growth Hormone in Pichia Pastoris.	Methanol	23-31	growth hormone 1	Homo sapiens	87-101
29552064-3	2017	This work aimed to develop a new experimental method and compare the effect of various fractions of sorbitol in mixed feeding strategy with stepwise addition of methanol to maximize the productivity of human growth hormone.	Methanol	161-169	growth hormone 1	Homo sapiens	208-222
28964007-1	2017	Infrared plus vacuum ultraviolet (IR + VUV) photoionization vibrational spectroscopy of 2-butanone/methanol clusters [MEK (MeOH)n, n = 1-4] is performed to explore structures associated with hydrogen bonding of MeOH molecules to the carbonyl functional group of the ketone.	Methanol	123-127	mitogen-activated protein kinase kinase 7	Homo sapiens	118-121
28964007-2	2017	IR spectra and X3LYP/6-31++G(d,p) calculations show that multiple isomers of MEK (MeOH)n are generated in the molecular beam as a result of several hydrogen bonding sites available to the clusters throughout the size range investigated.	Methanol	82-86	mitogen-activated protein kinase kinase 7	Homo sapiens	77-80
28964007-5	2017	Calculations suggest that the n = 3 cluster isomers adopt structures in which the MEK molecule is inserted into the cyclic MeOH hydrogen bond network.	Methanol	123-127	mitogen-activated protein kinase kinase 7	Homo sapiens	82-85
28890979-4	2017	d-TST is shown to be suitable for describing the overall rate constant for the CH3OH + H reaction (an archetype of the moderate tunnelling regime) with the precision required for practical applications.	Methanol	79-84	thiosulfate sulfurtransferase	Homo sapiens	2-5
28849635-1	2017	A Co(II) complex, [Co(L)2]Cl2, 1 of the ligand L (L = bis(2-ethyl-4-methylimidazol-5-yl)methane) upon reaction with H2O2 in methanol solution at -40  C resulted in the formation of the corresponding Co(III)-peroxo complex [Co(L)2(O2)]+ (2).	Methanol	124-132	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	2-8
28793192-5	2017	The sorption and diffusion behavior of water and methanol was well described by means of the type II sorption model (BET theory).	Methanol	49-57	delta/notch like EGF repeat containing	Homo sapiens	117-120
28916799-2	2017	Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state.	Methanol	6-10	prolactin induced protein	Homo sapiens	67-70
28735729-14	2017	CONCLUSIONS: These results clearly demonstrate that the MeOH extracts and flavonoids from Korean milk thistle protected HepG2 cells against oxidative damage triggered by t-BHP principally by modulating ROS generation and restoring depleted GSH levels in addition to the increased Nrf-2/HO-1 signaling cascade.	Methanol	56-60	NFE2 like bZIP transcription factor 2	Homo sapiens	280-285
28735729-14	2017	CONCLUSIONS: These results clearly demonstrate that the MeOH extracts and flavonoids from Korean milk thistle protected HepG2 cells against oxidative damage triggered by t-BHP principally by modulating ROS generation and restoring depleted GSH levels in addition to the increased Nrf-2/HO-1 signaling cascade.	Methanol	56-60	heme oxygenase 1	Homo sapiens	286-290
28916799-2	2017	Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state.	Methanol	73-77	prolactin induced protein	Homo sapiens	46-49
28916799-1	2017	In this present work, we theoretically investigate the excited state mechanism for the 2-(phenyl)imidazo[4,5-c]pyridine (PIP-C) molecule combined with methanol (MeOH) solvent molecules.	Methanol	151-159	prolactin induced protein	Homo sapiens	121-124
28916799-2	2017	Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state.	Methanol	73-77	prolactin induced protein	Homo sapiens	67-70
28916799-1	2017	In this present work, we theoretically investigate the excited state mechanism for the 2-(phenyl)imidazo[4,5-c]pyridine (PIP-C) molecule combined with methanol (MeOH) solvent molecules.	Methanol	161-165	prolactin induced protein	Homo sapiens	121-124
28916799-6	2017	While the intersection of potential energy curves of S0 and S1 states result in the nonradiation transition from S1 to S0 state, which successfully explain why the emission peak of the proton-transfer PIP-C-MeOH-PT form could not be reported in previous experiment.	Methanol	207-211	prolactin induced protein	Homo sapiens	201-204
28916799-2	2017	Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state.	Methanol	6-10	prolactin induced protein	Homo sapiens	46-49
28478952-3	2017	The methanol extract of Carissa carandas leaves (MELC) was applied on DPPH and ABTS experiments to determine its antioxidant activity.	Methanol	4-12	melanocyte population size	Mus musculus	49-53
28870197-13	2017	The brine shrimp lethality assay ranked 78.60% extracts as cytotoxic (LC50 &lt;= 250 mug/ml) whereas significant THP-1 inhibition was shown by methanol-acetone extract (IC50 4.70 +- 0.43 mug/ml).	Methanol	143-151	GLI family zinc finger 2	Homo sapiens	113-118
28870197-14	2017	The antiproliferative activity against Hep-G2 hepatoma cancer cell line was demonstrated by n-hexane, ethylacetate and methanol-distilled water (IC50 8.65-8.95 mug/ml) extracts.	Methanol	119-127	DNL-type zinc finger	Homo sapiens	39-42
28838343-7	2017	Although BrdU incorporation was not observed in MCF-7 cells treated with methanol extract at a concentration above 0.2 mg/mL, a significant decrease was observed int he percentage of PCNA immunoreactive cells in groups treated with 0.2, 0.4, 06, and 0.8 mg/mL methanol extracts of C.pocillum (49+-6.3, 44+-5.2, 23+-2.5, 0, respectively) compared to that of control (85+-4.5).	Methanol	260-268	proliferating cell nuclear antigen	Homo sapiens	183-187
28502116-11	2017	70% methanol extract potentially inhibited the NO and TNF-alpha production (18.43 mum and 1556.22 pg/ml, respectively, 6 h).	Methanol	4-12	tumor necrosis factor	Mus musculus	54-63
28820222-1	2017	Deactivation of an anode catalyst resulting from the poisoning of COad-like intermediates is one of the major problems for methanol and ethanol electro-oxidation reactions (MOR &amp; EOR), and remains a grand challenge towards achieving high performance for direct alcohol fuel cells (DAFCs).	Methanol	123-131	opioid receptor mu 1	Homo sapiens	173-176
28766623-3	2017	Addition of methanol to the compounds derived from addition of Ph2PBpin to carbodiimides, isocyanates, and isothiocyanates resulted in traditional hydrophosphination products.	Methanol	12-20	polyhomeotic homolog 2	Homo sapiens	63-66
28735170-4	2017	Therefore, atomistic molecular dynamics (MD) simulations have been carried out to investigate the effect of different solvents (water, urea/water, MeOH and DMSO) on the structure and conformations of apoptotic cyt-c (Fe3+).	Methanol	147-151	cytochrome c, somatic	Homo sapiens	210-215
28735170-11	2017	Essential dynamics analysis implies that the overall motions of cyt-c in water, MeOH and urea/water are involved in three to four eigenvectors and in first eigenvector in DMSO.	Methanol	80-84	cytochrome c, somatic	Homo sapiens	64-69
28825741-2	2017	Subsequently, the addition of methanol vapour to the reaction mixture, in the presence of excess oxygen, afforded the efficient simultaneous post-photolysis formation of HO2 radicals using well-defined chemistry.	Methanol	30-38	heme oxygenase 2	Homo sapiens	170-173
28712290-1	2017	A key challenge in developing fuel cells is the fabrication of low-cost electrocatalysts with high activity and long durability for the two half-reactions, i.e., the methanol/ethanol oxidation reaction (MOR/EOR) and the oxygen reduction reaction (ORR).	Methanol	166-174	opioid receptor mu 1	Homo sapiens	203-206
28726396-4	2017	Surprisingly, the EtOAc fraction of MeOH extracts from native Korean plant species Sasa coreana Nakai (SCN) has shown potent anti-inflammatory properties; SCN pretreatment inhibited nitric oxide (NO) production (p &lt; 0.01) and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated macrophages.	Methanol	36-40	nitric oxide synthase 2, inducible	Mus musculus	229-260
28726396-4	2017	Surprisingly, the EtOAc fraction of MeOH extracts from native Korean plant species Sasa coreana Nakai (SCN) has shown potent anti-inflammatory properties; SCN pretreatment inhibited nitric oxide (NO) production (p &lt; 0.01) and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated macrophages.	Methanol	36-40	nitric oxide synthase 2, inducible	Mus musculus	262-266
28610486-6	2017	The characterization results showed that resveratrol in glycyrrhizic acid-conjugated human serum albumin nanoparticles wrapping resveratrol nanoparticles existed in amorphous state and the residual amounts of chloroform and methanol in nanoparticles were separately less than the international conference on harmonization (ICH) limit.	Methanol	224-232	albumin	Homo sapiens	91-104
28665420-1	2017	The kinetics of the methylation of triethylamine (NEt3) with dimethyl carbonate (DMC) in methanol have been investigated by means of in situ ATR-IR-spectroscopy.	Methanol	89-97	tetraspanin 2	Homo sapiens	50-54
28523730-9	2017	By contrast, the use of methanol as a carbon source generated small cells and a shift in carbon metabolism toward the dissimilatory pathway by the upregulation of formaldehyde dehydrogenase gene and the downregulation of those of the central metabolic.	Methanol	24-32	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	163-189
28602073-2	2017	The system produces hydrogen at a turnover of about 240 mumol of H2 (mumol protein)-1 h-1 and 17.74 mmol of H2 (mumol protein)-1 h-1 under monochromatic green and white light, respectively, at ambient conditions, in water at neutral pH and room temperature, with methanol as a sacrificial electron donor.	Methanol	263-271	relaxin 2	Homo sapiens	65-89
28599082-1	2017	Fe(CO){CO(CH2 )5 CH2 -pyrene}(Cp)(PPh3 ) (Fp-pyrene) is soluble in DMSO and THF, but insoluble in water, methanol, and ethanol.	Methanol	105-113	caveolin 1	Homo sapiens	34-38
28440570-8	2017	RESULTS AND CONCLUSIONS: The steroidal SARM YK-11 was found to readily protonate under ESI conditions followed by substantial in-source dissociation processes eliminating methanol, acetic acid methyl ester, and/or ketene.	Methanol	171-179	sterile alpha and TIR motif containing 1	Homo sapiens	39-43
28839362-7	2017	The methanol extracts of seeds also demonstrated the highest inhibition of TNF-alpha, IL-1beta, IL-6, and IFN-gamma production.	Methanol	4-12	tumor necrosis factor	Homo sapiens	75-84
31457662-2	2017	In the presence of PPh3 or CO, these ruthenium complexes reacted with NH4PF6 in CH2Cl2 or CH3OH to give a series of ionic products 5-9.	Methanol	90-95	protein phosphatase 4 catalytic subunit	Homo sapiens	19-23
28918611-4	2017	In this work, antioxidant and anti-tyrosinase activity of MeOH extract from Pistacia vera hull (MPH) were evaluated in vitro, respectively, by DPPH radical scavenging and mushroom tyrosinase activity assays.	Methanol	58-62	tyrosinase	Homo sapiens	35-45
28918611-4	2017	In this work, antioxidant and anti-tyrosinase activity of MeOH extract from Pistacia vera hull (MPH) were evaluated in vitro, respectively, by DPPH radical scavenging and mushroom tyrosinase activity assays.	Methanol	58-62	tyrosinase	Homo sapiens	180-190
28839362-7	2017	The methanol extracts of seeds also demonstrated the highest inhibition of TNF-alpha, IL-1beta, IL-6, and IFN-gamma production.	Methanol	4-12	interleukin 1 beta	Homo sapiens	86-94
28839362-7	2017	The methanol extracts of seeds also demonstrated the highest inhibition of TNF-alpha, IL-1beta, IL-6, and IFN-gamma production.	Methanol	4-12	interleukin 6	Homo sapiens	96-100
28839362-7	2017	The methanol extracts of seeds also demonstrated the highest inhibition of TNF-alpha, IL-1beta, IL-6, and IFN-gamma production.	Methanol	4-12	interferon gamma	Homo sapiens	106-115
28773088-2	2017	Crystals were grown by layering MeOH solutions of Co(NCS)2 over a CHCl3 or 1,2-C6H4Cl2 solution of the respective ligand at room temperature.	Methanol	32-36	cytosolic thiouridylase subunit 2	Homo sapiens	50-58
28340396-2	2017	The chemosensor 1 is developed as a dual chemosensor for detection of Hg2+ and Al3+ ions in CH3OH, which exhibited a color change from light yellow to dark yellow with Hg2+ ions, enabling 1 a suitable "bare eye" indicator for Hg2+ ions.	Methanol	92-97	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	70-73
28561569-2	2017	For that, a strategic design and synthesis of three pentacoordinate CoII complexes [Co(bbp)Cl2] (MeOH) (1), [Co(bbp)Br2] (MeOH) (2), and [Co(bbp)(NCS)2] (3) has been achieved by using the tridentate coordination environment of the ligand in conjunction with the accommodating terminal ligands (i.e., chloride, bromide, and thiocyanate).	Methanol	97-102	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	68-72
28561569-2	2017	For that, a strategic design and synthesis of three pentacoordinate CoII complexes [Co(bbp)Cl2] (MeOH) (1), [Co(bbp)Br2] (MeOH) (2), and [Co(bbp)(NCS)2] (3) has been achieved by using the tridentate coordination environment of the ligand in conjunction with the accommodating terminal ligands (i.e., chloride, bromide, and thiocyanate).	Methanol	122-127	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	68-72
28340396-2	2017	The chemosensor 1 is developed as a dual chemosensor for detection of Hg2+ and Al3+ ions in CH3OH, which exhibited a color change from light yellow to dark yellow with Hg2+ ions, enabling 1 a suitable "bare eye" indicator for Hg2+ ions.	Methanol	92-97	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	168-171
28340396-2	2017	The chemosensor 1 is developed as a dual chemosensor for detection of Hg2+ and Al3+ ions in CH3OH, which exhibited a color change from light yellow to dark yellow with Hg2+ ions, enabling 1 a suitable "bare eye" indicator for Hg2+ ions.	Methanol	92-97	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	168-171
32264249-7	2017	However, the highest CBM migration rate, 1.76 mum2 min-1, was attained by regenerating alpha-cellulose in methanol, which also resulted in the maximum affinity of the biomolecule for the material.	Methanol	106-114	trafficking protein particle complex subunit 1	Homo sapiens	46-50
32264249-7	2017	However, the highest CBM migration rate, 1.76 mum2 min-1, was attained by regenerating alpha-cellulose in methanol, which also resulted in the maximum affinity of the biomolecule for the material.	Methanol	106-114	CD59 molecule (CD59 blood group)	Homo sapiens	51-56
28704188-13	2017	Methanol and aqueous extracts there were found to be effective inhibitors of alpha-glucosidase with an IC50 value of 20 mug GAE/ml and 55 mug GAE/ml, respectively.	Methanol	0-8	sucrase-isomaltase	Homo sapiens	77-94
28275780-5	2017	Most interestingly, permanent porosity could be observed for 1, originated from 4 A channel pores and confirmed by methanol adsorption experiments, which yielded an uptake of 7.43 wt% at 25  C; and respectively, anhydrates of 1, 2, 4 and 6 can be rehydrated upon exposure to ambient air, as evidenced by TGA and PXRD measurements.	Methanol	115-123	T-box transcription factor 1	Homo sapiens	304-307
27562502-2	2017	Herein we present an online ambient mass spectrometric approach for analyzing HCHO generated from methanol electro-oxidation, taking the advantage of high salt tolerance of desorption electrospray ionization mass spectrometry (DESI-MS).	Methanol	98-106	desumoylating isopeptidase 2	Homo sapiens	227-231
28430411-2	2017	Through using 2-methylimidazole as complex and methanol as solvent, the as-prepared NiCo-LDH/CFC shows a (003) facet preferential growth and an expanded interlayer spacing structure, resulting in a unique 3D porous nanostructure with a thickness of nanosheets of around 5-7 nm that shows high energy storage performance.	Methanol	47-55	tubulin folding cofactor C	Homo sapiens	93-96
28452486-6	2017	Furthermore, the Co,N-HCNP electrocatalyst also presents outstanding electrochemical durability and methanol tolerance in comparison with Pt/C.	Methanol	100-108	XPA binding protein 2	Homo sapiens	22-26
28088446-6	2017	We further characterized that these unique vesicles are soluble in organic solvents (e.g. chloroform-methanol mixture and ethanol) which can be prevented by a lipid-stabilizing fixative (e.g. OsO4) and that they are co-localized with, but do not monopolize, the major markers (e.g. caveolin-1 and GM1) for lipid rafts (a nano-sized detergent-resistant domains in the plasma membrane).	Methanol	101-109	caveolin 1	Homo sapiens	282-292
28553537-1	2017	Solvent effects in a series of Fe(iii) spin crossover (SCO) complexes [Fe(qsal-I)2]OTf sol (sol = MeOH 1, EtOH 2, n-PrOH 3, i-PrOH 4, acetone 5 and MeCN 6) are explored.	Methanol	98-102	spindlin 1	Homo sapiens	39-43
28320099-0	2017	Light-Emitting Diode (LED) therapy improves occipital cortex damage by decreasing apoptosis and increasing BDNF-expressing cells in methanol-induced toxicity in rats.	Methanol	132-140	brain-derived neurotrophic factor	Rattus norvegicus	107-111
28320099-4	2017	Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain.	Methanol	0-8	RNA binding fox-1 homolog 3	Rattus norvegicus	109-113
28320099-4	2017	Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain.	Methanol	0-8	glial fibrillary acidic protein	Rattus norvegicus	131-162
28320099-4	2017	Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain.	Methanol	0-8	glial fibrillary acidic protein	Rattus norvegicus	164-169
28320099-4	2017	Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain.	Methanol	0-8	brain-derived neurotrophic factor	Rattus norvegicus	204-237
28320099-4	2017	Methanol administration showed a reduction in the number of RGCs, loss of neurons (neuronal nuclear antigen, NeuN+), activation of glial fibrillary acidic protein (GFAP+) expressing cells, suppression of brain-derived neurotrophic factor (BDNF+) positive cells, increase in apoptosis (caspase 3+) and enhancement of nitric oxide (NO) release in serum and brain.	Methanol	0-8	brain-derived neurotrophic factor	Rattus norvegicus	239-243
28320099-6	2017	In addition, the number of BDNF positive cells was significantly higher in the visual cortex of LED-treated group, in comparison to methanol-intoxicated and control groups.	Methanol	132-140	brain-derived neurotrophic factor	Rattus norvegicus	27-31
28300405-3	2017	On the other hand, in the case of Am-POSS, T8-POSS and a mixture of T10- and T12-POSSs could be isolated by treatment with ethanol-methanol mixed solvent and 1-propanol.	Methanol	131-139	CD6 molecule	Homo sapiens	77-80
28390257-5	2017	Here, we employed nanosecond laser flash photolysis (LFP) to generate RET+ (lambdamax=580nm in methanol) and examine its reactivity toward a wide range of biological molecules including amino acids, vitamins, carotenoids, naturally-occurring phenols, neurotransmitters such as catecholamines, wide range of phenol derivatives and some selected electron-donors.	Methanol	95-103	ret proto-oncogene	Homo sapiens	70-73
27989880-7	2017	Total flavonoids of purified methanol extracts of Spatholobi Caulis (PSC) were determined using ultraviolet spectrophotometry.	Methanol	29-37	PSC	Homo sapiens	69-72
28113077-3	2017	The highest COD removal of up to 97% was observed when the influent concentration was increased by the addition of methanol (up to 25gL-1 as COD).	Methanol	115-123	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	12-15
28113077-3	2017	The highest COD removal of up to 97% was observed when the influent concentration was increased by the addition of methanol (up to 25gL-1 as COD).	Methanol	115-123	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	141-144
28160415-4	2017	The hierarchical OCN-Tube shows excellent photocatalytic CO2 reduction performance under visible light, with methanol evolution rate of 0.88 micromol g-1 h-1 , which is five times higher than bulk g-C3 N4 (0.17 micromol g-1 h-1 ).	Methanol	109-117	bone gamma-carboxyglutamate protein	Homo sapiens	17-20
28333105-5	2017	Among the five most potent extracts, the methanol extract of Morus alba wood (MAM) demonstrated a significant reduction in intracellular tyrosinase and melanin content in B16F10 melanoma cells.	Methanol	41-49	tyrosinase	Homo sapiens	137-147
28207286-5	2017	A mobile phase of formic acid (0.1%) in water and methanol through a gradient of composition and a flow rate of 0.3 ml min-1 resulted in good separations of the analytes.	Methanol	50-58	CD59 molecule (CD59 blood group)	Homo sapiens	119-124
28086170-3	2017	The highest yield 90.84% of FAME was obtained by filling Dixon rings as packing with the condition of the temperature was 350 C, the pressure was 22MPa, the molar ratio of methanol to oil was 42:1.	Methanol	172-180	benign adult familial myoclonic epilepsy 1	Homo sapiens	28-32
28182184-5	2017	We found electrochemical photovoltage and photocurrent responses as SPP-induced hot carriers drive both solution-based oxidation of methanol and the anodic half-reaction of photoelectrochemical water-splitting in sodium hydroxide solution.	Methanol	132-140	histocompatibility minor 13	Homo sapiens	68-71
28462147-10	2017	The methanol and ethanol leaf extracts were found to be selectively cytotoxic in vitro to (DU-145 and PC-3) prostate cancer cell lines with IC50 values 529.44 +- 42.07 mug/mL and 677.11 +- 37.01 mug/mL for DU-145 and 547.55 +- 33.52 mug/mL and 631.99 +- 50.24 mug/mL for PC-3 respectively, while it had no cytotoxic effect on normal mice embryo fibroblast cells.	Methanol	4-12	chromobox 8	Homo sapiens	102-106
28462147-10	2017	The methanol and ethanol leaf extracts were found to be selectively cytotoxic in vitro to (DU-145 and PC-3) prostate cancer cell lines with IC50 values 529.44 +- 42.07 mug/mL and 677.11 +- 37.01 mug/mL for DU-145 and 547.55 +- 33.52 mug/mL and 631.99 +- 50.24 mug/mL for PC-3 respectively, while it had no cytotoxic effect on normal mice embryo fibroblast cells.	Methanol	4-12	chromobox 8	Homo sapiens	271-275
27910158-10	2017	The crude water extract, the methanol extract, and the methanol extract derived AQ fraction showed alpha-glucosidase inhibiting effects.	Methanol	29-37	sucrase-isomaltase	Homo sapiens	99-116
27352386-4	2017	However, even though immediate drug release from such fibers can easily be realized, fiber mat fabrication providing long-term controlled protein release still bares challenges.In this study, lysozyme was encapsulated in poly(vinyl alcohol) fibers followed by post-modification with MeOH, glutaraldehyde vapor, or UV light.	Methanol	283-287	lysozyme	Homo sapiens	192-200
28649059-2	2017	The aim of this study was to evaluate the potential protective effects of methanol extract of R. sativus seeds (RSME) against hypogonadism induced with carbon tetrachloride (CCl4) in Sprague-Dawley male rats.	Methanol	74-82	C-C motif chemokine ligand 4	Rattus norvegicus	174-178
27910158-10	2017	The crude water extract, the methanol extract, and the methanol extract derived AQ fraction showed alpha-glucosidase inhibiting effects.	Methanol	55-63	sucrase-isomaltase	Homo sapiens	99-116
28128570-5	2017	In this study, we calculated potentials of mean force for water, ammonia, urea, molecular oxygen, and methanol across the urea transporter B (UT-B) and aquaporin-1 (AQP1), using 3D-RISM, as well as using MD simulations and umbrella sampling.	Methanol	102-110	aquaporin 1 (Colton blood group)	Homo sapiens	165-169
28082716-6	2017	AtPMEI expression is strictly regulated by jasmonic acid and ethylene signaling, while only AtPMEI11 expression is controlled by PME-related damage-associated molecular patterns, such as oligogalacturonides and methanol.	Methanol	211-219	pectin methylesterase inhibitor 1	Arabidopsis thaliana	92-100
27956356-0	2017	A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma.	Methanol	15-23	heart and neural crest derivatives expressed 2	Mus musculus	130-133
28111863-0	2017	Methanol-Triggered Vapochromism Coupled with Solid-State Spin Switching in a Nickel(II)-Quinonoid Complex.	Methanol	0-8	spindlin 1	Homo sapiens	57-61
28181016-3	2017	It is shown that methanol is adsorbed much more easily to the cationic Ptn+ than to the neutral and anionic Ptn0/-.	Methanol	17-25	pleiotrophin	Homo sapiens	71-74
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	cyclin D1	Homo sapiens	131-140
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	cyclin dependent kinase 2	Homo sapiens	177-182
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	cyclin dependent kinase 4	Homo sapiens	184-188
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	cyclin dependent kinase 6	Homo sapiens	190-194
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	H3 histone pseudogene 16	Homo sapiens	196-199
28101580-12	2017	MeOH fraction arrested HepG2 cells at the G0/G1 phase in a concentration-dependent manner, and resulted in decreased expression of cyclin D1, cyclin E, cyclin-dependent kinase (CDK)2, CDK4, CDK6, p21, and p27.	Methanol	0-4	dynactin subunit 6	Homo sapiens	205-208
28101580-14	2017	MeOH fraction treatment also arrested HepG2 cells in the S phase, with decreased expression of cyclin A, CDK2, and CDC25A.	Methanol	0-4	cyclin A2	Homo sapiens	95-103
28101580-14	2017	MeOH fraction treatment also arrested HepG2 cells in the S phase, with decreased expression of cyclin A, CDK2, and CDC25A.	Methanol	0-4	cyclin dependent kinase 2	Homo sapiens	105-109
28101580-14	2017	MeOH fraction treatment also arrested HepG2 cells in the S phase, with decreased expression of cyclin A, CDK2, and CDC25A.	Methanol	0-4	cell division cycle 25A	Homo sapiens	115-121
30428220-5	2017	In this study, we showed that the MeOH extract from R. sativus sprout exhibits significant but variable cytotoxic effects on human lung adenocarcinoma cells depending on their p53 status.	Methanol	34-38	tumor protein p53	Homo sapiens	176-179
30428220-6	2017	The MeOH extract decreased the viability of p53-deleted human lung cancer cells (H1299 and Calu-6) by inducing apoptosis; this effect, however, did not occur for wild-type p53 cancer cells (A549), for cells expressing a p53 mutant lacking the C terminus (H1264), or for .	Methanol	4-8	tumor protein p53	Homo sapiens	44-47
28163969-6	2017	MATERIALS AND METHODS: The crude methanol extract was prepared by cold extraction method and was assessed for acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory activities by the Ellman"s method.	Methanol	33-41	acetylcholinesterase (Cartwright blood group)	Homo sapiens	110-130
28088197-8	2017	The methanol inducible promoter AOX1 was used to drive expression of the native and histidine tagged forms of pro-relaxin H2 in dual phase fed-batch experiments on the 22 L scale.	Methanol	4-12	aldehyde oxidase 1	Homo sapiens	32-36
28088197-8	2017	The methanol inducible promoter AOX1 was used to drive expression of the native and histidine tagged forms of pro-relaxin H2 in dual phase fed-batch experiments on the 22 L scale.	Methanol	4-12	relaxin 2	Homo sapiens	110-124
27876502-3	2017	MATERIALS AND METHODS: MeOH extracts (MOD) and BuOH extracts (BOD) were prepared and examined for their ability to inhibit phorbol myristate acetate (PMA)-induced matrix metalloproteinase (MMP)-9 and intercellular adhesion molecule (ICAM)-1 expressions in MCF-7 human breast cancer cells.	Methanol	23-27	matrix metallopeptidase 9	Homo sapiens	163-195
28163969-6	2017	MATERIALS AND METHODS: The crude methanol extract was prepared by cold extraction method and was assessed for acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory activities by the Ellman"s method.	Methanol	33-41	butyrylcholinesterase	Homo sapiens	142-163
28163969-6	2017	MATERIALS AND METHODS: The crude methanol extract was prepared by cold extraction method and was assessed for acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory activities by the Ellman"s method.	Methanol	33-41	butyrylcholinesterase	Homo sapiens	165-170
29199243-1	2017	The methanol extract of the roots and stems of Daphne genkwa and its constituents yuanhuacin (1) and genkwanine N were previously reported to have Nurr1 activating effects and neuroprotective effects in an animal model of Parkinson"s disease (PD).	Methanol	4-12	nuclear receptor subfamily 4, group A, member 2	Mus musculus	147-152
29358968-3	2017	Treatment with methanol extract of H. antidysenterica bark (HABE) inhibited cell viability and BrdU incorporation and induced apoptotic cell death in Ca9-22 gingival and HSC-3 tongue SCC cells.	Methanol	15-23	DnaJ heat shock protein family (Hsp40) member B7	Homo sapiens	170-175
27998673-5	2017	The highest amount of hEGF with an average yield of 2.27mug/mL was obtained through an induction of the culture with 0.5% (v/v) methanol for 60h.	Methanol	128-136	epidermal growth factor	Homo sapiens	22-26
29408812-5	2017	Then, adding and maintaining methanol at 0.5% (v/v, methanol/cultivation) after about 48 h of fermentation achieved a high expression of human cathepsin S in a 5-L bioreactor.	Methanol	29-37	cathepsin S	Homo sapiens	143-154
27824613-2	2017	In this study, the protective effect of methanol extract of NL against carbon tetrachloride (CCl4)-induced chronic hepatotoxicity in rats was investigated.	Methanol	40-48	C-C motif chemokine ligand 4	Rattus norvegicus	93-97
29408812-5	2017	Then, adding and maintaining methanol at 0.5% (v/v, methanol/cultivation) after about 48 h of fermentation achieved a high expression of human cathepsin S in a 5-L bioreactor.	Methanol	52-60	cathepsin S	Homo sapiens	143-154
29408812-6	2017	The results demonstrate that the maximum activity of human cathepsin S in the fermentation supernatant reached 7,152 U/L after 96 h of methanol induction.	Methanol	135-143	cathepsin S	Homo sapiens	59-70
29408812-9	2017	The glycerol fed-batch controlling strategy and method of maintaining methanol at a constant concentration of 0.5% (v/v, methanol/cultivation) in the induction stage was efficient for P. pastoris growth and the expression of human cathepsin S.	Methanol	70-78	cathepsin S	Homo sapiens	231-242
29408812-9	2017	The glycerol fed-batch controlling strategy and method of maintaining methanol at a constant concentration of 0.5% (v/v, methanol/cultivation) in the induction stage was efficient for P. pastoris growth and the expression of human cathepsin S.	Methanol	121-129	cathepsin S	Homo sapiens	231-242
28603108-3	2017	The separation was carried out on C18 column by using mobile phase as mixture of water and methanol (45:55%v/v).	Methanol	91-99	Bardet-Biedl syndrome 9	Homo sapiens	34-37
27932551-14	2017	All methods of AUM enhanced PLCzeta visualization efficacy in mouse and human methanol-fixed sperm compared to without AUM (P &lt; 0.05 for all AUM interventions), while no significant change was observed in methanol-fixed porcine sperm before and after.	Methanol	78-86	phospholipase C, zeta 1	Mus musculus	28-35
27647013-15	2016	Both EtOAc and MeOH extract-administered groups displayed significant remission in the levels of TNF-alpha, VEGF and IL-6.	Methanol	15-19	tumor necrosis factor	Rattus norvegicus	97-106
30187726-13	2017	Methanol extract was also active against most test strains including Candida tropicalis with the minimum fungicidal concentration value of 3.75 mg mL-1.	Methanol	0-8	L1 cell adhesion molecule	Mus musculus	147-151
27702689-4	2016	MATERIALS AND METHODS: In vitro inhibition assay of the sEH was conducted for the methanol and ethanol extracts of 27 anti-inflammatory TCMs.	Methanol	82-90	epoxide hydrolase 2, cytoplasmic	Mus musculus	56-59
27824191-4	2016	Notably, the prepared N,S-hcs electrocatalysts provided four electron oxygen reduction selectivity, long-term durability and high resistance to methanol poisoning, all of which represented improvements over the conventional Pt/C electrocatalyst.	Methanol	144-152	holocarboxylase synthetase	Homo sapiens	26-29
27647013-15	2016	Both EtOAc and MeOH extract-administered groups displayed significant remission in the levels of TNF-alpha, VEGF and IL-6.	Methanol	15-19	vascular endothelial growth factor A	Rattus norvegicus	108-112
27647013-15	2016	Both EtOAc and MeOH extract-administered groups displayed significant remission in the levels of TNF-alpha, VEGF and IL-6.	Methanol	15-19	interleukin 6	Rattus norvegicus	117-121
28004102-7	2016	According to Langmuir model data, maximum adsorption capacities (qm) of Fez natural clay and zeolite toward methanol (M), toluene (T) and benzaldehyde (B) at 300 K are 8, 0.89 and 3.1 mmol g-1, and 15, 1.91 and 13.9 mmol g-1 respectively.	Methanol	108-116	FEZ family zinc finger 1	Homo sapiens	72-75
27837997-5	2016	However, the optimum, or near optimum, flow rate was 5mL-min-1, producing a system pressure of 580bar (with 40% methanol, outlet pressure 120bar).	Methanol	112-120	CD59 molecule (CD59 blood group)	Homo sapiens	57-62
27829416-5	2016	METHODS: Three different extracts (water, methanol and ethanol) from leaves, flowers and tubers of A. microcarpus were evaluated for their inhibitory effect on tyrosinase activity using L-3,4-dihydroxyphenylalanine (L-DOPA) as substrate.	Methanol	42-50	tyrosinase	Mus musculus	160-170
28032325-5	2016	Finally, the result proves that Pt-Ru/TNT-C catalyst shows high performance in methanol oxidation as the highest current density achieved at 3.3 mA/cm2 (normalised by electrochemically active surface area) and high catalyst tolerance towards poisoning species was established.	Methanol	79-87	chromosome 16 open reading frame 82	Homo sapiens	38-41
27823632-3	2016	METHODS: Activity-guided fractionation and repeated chromatographic separation of the n-hexane fraction of the aqueous methanol extract over silica gel, RP C18, and Sephadex LH-20 led to the isolation of three compounds.	Methanol	119-127	RNA polymerase II, I and III subunit H	Homo sapiens	153-159
27546451-7	2016	Additionally, we determined that the optimal induction time was 72 h and the optimal induction methanol concentration was 1% for the expression of rPINK1 in P. pastoris.	Methanol	95-103	PTEN induced kinase 1	Rattus norvegicus	147-153
27595387-2	2016	This study reports, for the first time, the ACE inhibition of methanol extract/fractions from Azorean brown algae Fucus spiralis (Fs) determined by HPLC-UV method, their total phenolic content (TPC) quantified as phloroglucinol equivalents (PE) and the effect of the Fs dry powder methanol extracts (Fs-DME) storage temperature on ACE inhibition.	Methanol	62-70	angiotensin I converting enzyme	Homo sapiens	44-47
28032325-0	2016	TiO2 Nanotube-Carbon (TNT-C) as Support for Pt-based Catalyst for High Methanol Oxidation Reaction in Direct Methanol Fuel Cell.	Methanol	71-79	chromosome 16 open reading frame 82	Homo sapiens	22-25
28032325-0	2016	TiO2 Nanotube-Carbon (TNT-C) as Support for Pt-based Catalyst for High Methanol Oxidation Reaction in Direct Methanol Fuel Cell.	Methanol	109-117	chromosome 16 open reading frame 82	Homo sapiens	22-25
27889107-1	2016	We recently demonstrated that California table grapes and a methanol-extractable, polyphenol-rich fraction decreased adiposity, insulin resistance, or markers of inflammation in high-fat fed mice.	Methanol	60-68	insulin	Homo sapiens	128-135
27907132-4	2016	In the first step the insulin precursor secreted during the methanol induction phase is recovered directly from the culture broth using Tangential Flow Filtration with a Prostak  module eliminating the laborious and time-consuming multi-step clarification, including centrifugation.	Methanol	60-68	insulin	Homo sapiens	22-29
27980840-2	2016	The CoII cation is octa-hedrally coordinated by two terminal N-bonding thio-cyanate anions, two methanol mol-ecules and two 3,5-di-methyl-pyridine ligands into a discrete complex.	Methanol	96-104	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
27711734-5	2016	When applied to a photocatalyst for H2 production from water containing methanol under simulated solar light, the layered titanate/P25 mixture showed considerably enhanced activity and the apparent quantum yield was 23% (at 320 nm).	Methanol	72-80	tubulin polymerization promoting protein	Homo sapiens	131-134
27785497-2	2016	The sorption behavior of Li(Na)-EMT samples towards water, methanol and a mixture of both (50 : 50) was studied by combined thermogravimetric and infrared spectroscopic methods.	Methanol	59-67	IL2 inducible T cell kinase	Homo sapiens	32-35
27785497-5	2016	It was found that the methanol is replaced by water faster in the Li-EMT sample in comparison to the Na-EMT sample.	Methanol	22-30	IL2 inducible T cell kinase	Homo sapiens	69-72
27785497-5	2016	It was found that the methanol is replaced by water faster in the Li-EMT sample in comparison to the Na-EMT sample.	Methanol	22-30	IL2 inducible T cell kinase	Homo sapiens	104-107
27463192-0	2016	Erythropoietin as an adjunctive treatment for methanol-induced toxic optic neuropathy.	Methanol	46-54	erythropoietin	Homo sapiens	0-14
27671347-1	2016	In this letter, we report on the use of a cobalt phosphide nanowall array on conductive carbon cloth (CoP NA/CC) as an efficient catalyst electrode for methanol electro-oxidation under alkaline conditions.	Methanol	152-160	caspase recruitment domain family member 16	Homo sapiens	102-105
27671347-2	2016	This CoP NA/CC achieves a current density of 96 mA cm(-2) toward 0.5 M methanol at 0.5 V (versus a saturated calomel electrode (SCE)) in 1 M KOH.	Methanol	71-79	caspase recruitment domain family member 16	Homo sapiens	5-8
27267282-1	2016	A novel rhodamine-based dual probe Rh-2 for trivalent ferric ions (Fe(3+)) was successfully designed and synthesized, which exhibited a highly sensitive and selective recognition towards Fe(3+) with an enhanced fluorescence emission in methanol-water media (v/v=7/3, pH=7.2).	Methanol	236-244	Rh associated glycoprotein	Homo sapiens	35-39
27965942-2	2016	This study investigated the effects of the methanol extract of the aerial part of ELL on receptor activator of nuclear factor-kappa B ligand (RANKL)-induced osteoclast formation and signaling pathways.	Methanol	43-51	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	142-147
27731458-3	2016	Treatment of NiSO4 6H2O with pyaoxH2 and NEt3 in a 1 : 1 : 2 molar ratio in MeOH afforded 2 10H2O 26MeOH in good yield (65%).	Methanol	76-80	tetraspanin 2	Homo sapiens	41-45
27776508-5	2016	In this investigation we have evaluated the methanol extract of leaves for its hepatoprotective potential against CCl4 induced hepatic injuries in rat.	Methanol	44-52	C-C motif chemokine ligand 4	Rattus norvegicus	114-118
27770652-1	2016	The carbonylation of methanol with carbon monoxide to generate methyl acetate over Cu-H-MOR and H-MOR zeolites is studied using solid-state NMR spectroscopy.	Methanol	21-29	opioid receptor mu 1	Homo sapiens	88-91
27770652-1	2016	The carbonylation of methanol with carbon monoxide to generate methyl acetate over Cu-H-MOR and H-MOR zeolites is studied using solid-state NMR spectroscopy.	Methanol	21-29	opioid receptor mu 1	Homo sapiens	98-101
28335315-7	2016	On the other hand, apparent activation energy Eap for the methanol oxidation was also determined finding-as a rate determining step-the COads diffusion to the OHads for the catalysts supported on carbon nanofibers.	Methanol	58-66	glutamyl aminopeptidase	Homo sapiens	46-49
27714287-3	2016	The performances of CRGO-P25-Au NCM modified ITO electrodes were evaluated towards the photoelectrochemical oxidation of methanol.	Methanol	121-129	CWC22 spliceosome associated protein homolog	Homo sapiens	32-35
27690397-4	2016	The CoII-LnIII assembly was synthesized from Ln(NO3)3 xH2O/Co(OAc)2 4H2O/H2vab/NaOMe in a 0.4:0.5:1:1 ratio in methanol.	Methanol	111-119	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
27829926-2	2016	The optimal conditions were found to be 10 mol % PdCl2(CH3CN)2 in methanol, offering yields up to 92%.	Methanol	66-74	phosducin like 2	Homo sapiens	49-54
27717086-0	2016	Low-Temperature Transformation of Methane to Methanol on Pd1 O4 Single Sites Anchored on the Internal Surface of Microporous Silicate.	Methanol	45-53	programmed cell death 1	Homo sapiens	57-60
27717086-3	2016	The selectivity for methanol production remains at 86.4 %, while the activity for methanol production at 95  C is about 2.78 molecules per Pd1 O4 site per second when 2.0 wt % CuO is used as a co-catalyst with the Pd1 O4 @ZSM-5.	Methanol	82-90	programmed cell death 1	Homo sapiens	139-142
27717086-3	2016	The selectivity for methanol production remains at 86.4 %, while the activity for methanol production at 95  C is about 2.78 molecules per Pd1 O4 site per second when 2.0 wt % CuO is used as a co-catalyst with the Pd1 O4 @ZSM-5.	Methanol	82-90	programmed cell death 1	Homo sapiens	214-217
27650357-6	2016	Large enhancement of fluorescence was observed upon formation of 1:1 complexes of 1,4-DAT with water or methanol, which is explained in terms of an increased separation of interacting (n,pi*) and (pi,pi*) electronic states in the H-bonded complexes, and/or a suppression of the intersystem crossing process.	Methanol	104-112	solute carrier family 6 member 3	Homo sapiens	86-89
27506249-8	2016	While Pd1 catalysts showed promising activity at low temperature in a methanol decomposition reaction, 14 cycle TiO2 protected Pd1 was less active at high temperature.	Methanol	70-78	programmed cell death 1	Homo sapiens	6-9
27625114-2	2016	In the top H-FAU layer with mild acidity, methanol is dehydrated to DME.	Methanol	42-50	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	13-16
27636231-6	2016	The sizes varied with different desolvating agents: for OVA, ethanol, and methanol both produced nanoparticles smaller than 100 nm; for alpha-LA, methanol produced the smallest nanoparticles.	Methanol	146-154	lactalbumin alpha	Homo sapiens	136-144
27537433-2	2016	In this work, we investigated the effect of H-bonds on the vibrational population relaxation and orientational relaxation dynamics of HN3 and N3(-) in methanol (CH3OH) and N,N-dimethyl sulfoxide (DMSO) using polarization-controlled infrared pump-probe spectroscopy and quantum chemical calculations.	Methanol	151-159	MT-RNR2 like 3 (pseudogene)	Homo sapiens	134-137
27537433-2	2016	In this work, we investigated the effect of H-bonds on the vibrational population relaxation and orientational relaxation dynamics of HN3 and N3(-) in methanol (CH3OH) and N,N-dimethyl sulfoxide (DMSO) using polarization-controlled infrared pump-probe spectroscopy and quantum chemical calculations.	Methanol	161-166	MT-RNR2 like 3 (pseudogene)	Homo sapiens	134-137
27537433-3	2016	Our detailed analysis of experimental and computational results reveals that both vibrational population relaxation and orientational relaxation dynamics of HN3 and N3(-) in CH3OH and DMSO are substantially dependent on the strength of the H-bonds between the probing solute and its surrounding solvent.	Methanol	174-179	MT-RNR2 like 3 (pseudogene)	Homo sapiens	157-160
27537433-7	2016	For HN3 and N3(-) in CH3OH and DMSO, the vibrational population relaxation becomes faster but the orientational relaxation becomes slower as the H-bond strength is increased.	Methanol	21-26	MT-RNR2 like 3 (pseudogene)	Homo sapiens	4-7
27598154-8	2016	Treatments of SH-SY5Y neuroblastoma cells with 100 microg/mL of methanol extract significantly reduced ADCY1 expression.	Methanol	64-72	adenylate cyclase 1	Homo sapiens	103-108
27627700-5	2016	The fraction obtained from the MeOH extract of FG, which showed potent transcription activity of PPAR-alpha, was fractionated by silica gel column chromatography into 16 subfractions, and further separation and crystallization gave compound 1 together with four known constituents of ginseng, including 20(R)- and 20(S)-protopanaxadiol, and 20(R)- and 20(S)-ginsenoside Rh1.	Methanol	31-35	peroxisome proliferator activated receptor alpha	Rattus norvegicus	97-107
27530158-4	2016	We have evaluated the protective potential of the methanol extract of M. buxifolia (MBM) in rat exposed to carbon tetrachloride (CCl4) toxicity.	Methanol	50-58	C-C motif chemokine ligand 4	Rattus norvegicus	129-133
27513212-4	2016	In this study, methanol extract of T. officinale leaves was initially analyzed for its cytotoxic activity in human hepatoma (Huh-7) and CHO cell lines.	Methanol	15-23	MIR7-3 host gene	Homo sapiens	125-130
28065997-0	2016	Rapid evaporation at the superheat limit of methanol, ethanol, butanol and n-heptane on platinum films supported by low-stress SiN membranes.	Methanol	44-52	embryonal Fyn-associated substrate	Homo sapiens	127-130
27519409-0	2016	Methanol Expression Regulator 1 (Mxr1p) Is Essential for the Utilization of Amino Acids as the Sole Source of Carbon by the Methylotrophic Yeast, Pichia pastoris.	Methanol	0-8	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	33-38
27599299-2	2016	We find that the lowest-energy structure in best agreement with experiment, calculated with CCSD, MP2, and B3LYP methods with aug-cc-pvdz basis set, is a tetrahedral arrangement of four methanol molecules with OH bonds oriented toward the center.	Methanol	186-194	tryptase pseudogene 1	Homo sapiens	98-101
27209450-7	2016	This is a typical case of degradation where co solvent methanol reacts with racecadotril leading to the formation of pseudo DPs, DP 6 and DP 5.	Methanol	55-63	harakiri, BCL2 interacting protein	Homo sapiens	129-142
27293214-7	2016	Acid hydrolysis of MUP with 6 N HCl liberates N-linked Hcy as Hcy-thiolactone, which is then extracted with chloroform/methanol.	Methanol	119-127	major urinary protein 21	Mus musculus	19-22
28487900-7	2016	MATERIALS AND METHODS: In this study, the anti-inflammatory effects of the ethyl acetate fraction of the methanol extract of FF (FFE) were assessed by measuring NO and PGE2 production by and intracellular ROS and protein levels of iNOS and COX-2 in RAW 264.7 cells.	Methanol	105-113	nitric oxide synthase 2, inducible	Mus musculus	231-235
28487900-7	2016	MATERIALS AND METHODS: In this study, the anti-inflammatory effects of the ethyl acetate fraction of the methanol extract of FF (FFE) were assessed by measuring NO and PGE2 production by and intracellular ROS and protein levels of iNOS and COX-2 in RAW 264.7 cells.	Methanol	105-113	cytochrome c oxidase II, mitochondrial	Mus musculus	240-245
27316830-5	2016	The tagged hPGHS-2 was expressed intracellularly in P. pastoris under the control of a constitutive or methanol-inducible promoter.	Methanol	103-111	prostaglandin-endoperoxide synthase 2	Homo sapiens	11-18
27465607-6	2016	Moreover, PtAg nanostructures can also serve as efficient electrocatalysts toward the methanol oxidation reaction, especially for Pt70Ag30 and Pt66Ag34 porous nanocrystals.	Methanol	86-94	rhomboid domain containing 3	Homo sapiens	10-14
27351070-2	2016	The present study investigates, for the first time, the protective effects of the methanol extract of Rhus tripartitum fruit (MERT) against CCl4-induced hepatotoxicity and cisplatin-induced nephrotoxicty in Wistar rats.	Methanol	82-90	C-C motif chemokine ligand 4	Rattus norvegicus	140-144
27135783-2	2016	Herein, we prepared Pt3 Co nanocrystals with improved catalytic performance towards CO2 hydrogenation to methanol.	Methanol	105-113	zinc finger protein 135	Homo sapiens	20-23
27154409-9	2016	AIM OF THE STUDY: The study was conducted to evaluate the antihypertensive activity of 80% methanol extract of CASA in animal model of hypertension as well as its vasorelaxant effect and possible underlying mechanisms in isolated guinea pig aorta.	Methanol	91-99	casein alpha s1	Rattus norvegicus	111-115
27406126-2	2016	In all examined chromatographic systems, linear relationships were established between retention parameters and the volume fraction of methanol in the mobile phase (r &gt; 0.985, 0.978, 0.981, 0.988 for the CN, RP-2, RP-8 and RP-18, respectively).	Methanol	135-143	RP2 activator of ARL3 GTPase	Homo sapiens	211-221
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	62-70	zinc finger DHHC-type palmitoyltransferase 16	Homo sapiens	119-123
27157767-3	2016	The analysis of binding capacities showed that the highest specificity towards gramine was achieved when 4-vinylbenzoic acid was used as the functional monomer in methanol to form the bulk imprinted polymer, MIP1 (imprinting factor equal to 21.3).	Methanol	163-171	MAPK associated protein 1	Homo sapiens	208-212
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	62-70	acylaminoacyl-peptide hydrolase	Homo sapiens	119-122
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	62-70	acylaminoacyl-peptide hydrolase	Homo sapiens	144-147
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	207-211	zinc finger DHHC-type palmitoyltransferase 16	Homo sapiens	119-123
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	207-211	acylaminoacyl-peptide hydrolase	Homo sapiens	119-122
27457731-3	2016	Here we report the photochemical dehydrogenation of anhydrous methanol at room temperature catalysed by o-aminophenol (apH2), o-aminophenolate (apH(-)) and the non-precious metal complex trans-[Fe(II)(apH)2(MeOH)2].	Methanol	207-211	acylaminoacyl-peptide hydrolase	Homo sapiens	144-147
27319975-3	2016	Herein we report the use of 18-crown-6 (18-C-6) as a host system to disaggregate suitably substituted PDI derivatives in methanol.	Methanol	121-129	complement C6	Homo sapiens	43-46
27319975-4	2016	18-C-6 formed complexes with amino-substituted PDIs in methanol, which led to disaggregation and enhanced emission from the systems.	Methanol	55-63	complement C6	Homo sapiens	3-6
27471465-9	2016	RD leaf and bark methanol extracts pre-treatment exhibited protection against CCl4 induced hepatotoxicity by reversing all the abnormal parameters to significant levels.	Methanol	17-25	C-C motif chemokine ligand 4	Rattus norvegicus	78-82
27095544-3	2016	Firstly, based on a previously postulated mechanism for the reaction of methanol on eta-alumina, a mechanism for methyl chloride synthesis over the eta-alumina catalyst is proposed.	Methanol	72-80	endothelin receptor type A	Homo sapiens	84-87
27095544-3	2016	Firstly, based on a previously postulated mechanism for the reaction of methanol on eta-alumina, a mechanism for methyl chloride synthesis over the eta-alumina catalyst is proposed.	Methanol	72-80	endothelin receptor type A	Homo sapiens	148-151
27761064-7	2016	RESULTS: GS extracts showed differential effect on CYP activities in the following order of inhibitory potency: ethyl acetate &gt; Chloroform &gt; methanol &gt; n-hexane &gt; aqueous &gt; DGA.	Methanol	147-155	peptidylprolyl isomerase G	Homo sapiens	51-54
26428528-7	2016	DISCUSSION AND CONCLUSION: Crataegus songarica methanol extract has a potential antioxidant effect as it protects the kidney and heart tissue against CCl4-induced toxicity, prevents DNA damage and showed strong anticancer activity.	Methanol	47-55	C-C motif chemokine ligand 4	Rattus norvegicus	150-154
27033608-1	2016	An intense screening of Pichia pastoris clones transformed with the gene of bovine chymosin under methanol-inducible AOX1 promoter was performed, obtaining a transformant clone with a higher milk-clotting activity value in comparison with our previous studies.	Methanol	98-106	chymosin	Bos taurus	83-91
27033608-1	2016	An intense screening of Pichia pastoris clones transformed with the gene of bovine chymosin under methanol-inducible AOX1 promoter was performed, obtaining a transformant clone with a higher milk-clotting activity value in comparison with our previous studies.	Methanol	98-106	aldehyde oxidase 1	Bos taurus	117-121
27033608-2	2016	The scaling of recombinant-chymosin production was carried out by a fed-batch strategy in a stirred-tank bioreactor using biodiesel-byproduct crude glycerol as the carbon source and pure methanol for the induction of chymosin expression, achieving a biomass concentration of 158 g DCW/L and a maximum coagulant activity of 192 IMCU/ml after 120 h of methanol induction.	Methanol	187-195	chymosin	Bos taurus	27-35
27033608-2	2016	The scaling of recombinant-chymosin production was carried out by a fed-batch strategy in a stirred-tank bioreactor using biodiesel-byproduct crude glycerol as the carbon source and pure methanol for the induction of chymosin expression, achieving a biomass concentration of 158 g DCW/L and a maximum coagulant activity of 192 IMCU/ml after 120 h of methanol induction.	Methanol	350-358	chymosin	Bos taurus	27-35
27033608-5	2016	Finally, reiterative methanol-inductions of recombinant chymosin expression in bioreactor demonstrated that the reutilization of cell biomass overcame the low enzyme productivity usually reached by P. pastoris system.	Methanol	21-29	chymosin	Bos taurus	56-64
27019125-5	2016	A higher methanol addition rate reduced FAME yields for lipase DF-CalT and A10D-CalT combinations while that of lipase AY-CalT combination improved.	Methanol	9-17	benign adult familial myoclonic epilepsy 1	Homo sapiens	40-44
27019125-6	2016	Optimizing the methanol addition rate for lipase AY-CalT resulted in a FAME yield of 88.1% at 2h and more than 95% at 6h.	Methanol	15-23	benign adult familial myoclonic epilepsy 1	Homo sapiens	71-75
27271603-2	2016	The in vitro study examined the effects of a MeOH crude extract (CruE) of A. camphorata and Antcin K (AnK; the main constituent of fruiting body of this mushroom) on membrane glucose transporter 4 (GLUT4) and phospho-Akt in C2C12 myoblasts cells.	Methanol	45-49	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	175-196
27228307-2	2016	During the screening for Nurr1 activators from natural sources using cell-based assay systems, a methanol extract of the combined stems and roots of Daphne genkwa was found to activate the transcriptional function of Nurr1 at a concentration of 3 mug/mL.	Methanol	97-105	nuclear receptor subfamily 4, group A, member 2	Rattus norvegicus	25-30
27228307-2	2016	During the screening for Nurr1 activators from natural sources using cell-based assay systems, a methanol extract of the combined stems and roots of Daphne genkwa was found to activate the transcriptional function of Nurr1 at a concentration of 3 mug/mL.	Methanol	97-105	nuclear receptor subfamily 4, group A, member 2	Rattus norvegicus	217-222
27241957-4	2016	The OH oscillators of coordinated methanol molecules facilitate the nonradiative pathway of the Eu(3+) emission; hence the emission at 613 nm almost disappears above the 0.50 equivalent of Eu(3+) (11 muM), while the UV emission at 357 nm remains mostly constant over the whole concentration range.	Methanol	34-42	latexin	Homo sapiens	200-203
27271603-2	2016	The in vitro study examined the effects of a MeOH crude extract (CruE) of A. camphorata and Antcin K (AnK; the main constituent of fruiting body of this mushroom) on membrane glucose transporter 4 (GLUT4) and phospho-Akt in C2C12 myoblasts cells.	Methanol	45-49	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	198-203
27262063-0	2016	Methanol extract of Codium fragile inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-9 and invasiveness of MDA-MB-231 cells by suppressing nuclear factor-kappaB activation.	Methanol	0-8	matrix metallopeptidase 9	Homo sapiens	80-106
27262063-1	2016	OBJECTIVE: To evaluate whether the methanol extract of Codium fragile (MECF) regulates tumor necrosis factor-alpha (TNF-alpha)-induced invasion of human breast cancer MDA-MB-231 cells by suppressing matrix metalloproteinase-9 (MMP-9).	Methanol	35-43	tumor necrosis factor	Homo sapiens	116-125
27262063-1	2016	OBJECTIVE: To evaluate whether the methanol extract of Codium fragile (MECF) regulates tumor necrosis factor-alpha (TNF-alpha)-induced invasion of human breast cancer MDA-MB-231 cells by suppressing matrix metalloproteinase-9 (MMP-9).	Methanol	35-43	matrix metallopeptidase 9	Homo sapiens	199-225
27145380-4	2016	This trihydride-tetrahydrideborate derivative and its PPh3 counterpart OsH3(kappa(2)-H2BH2)(IPr)(PPh3) (8) can be also obtained in a one-pot procedure, starting from 1 and 2 and using methanol at -60  C instead of 2-propanol as alcoholysis agent.	Methanol	184-192	protein phosphatase 4 catalytic subunit	Homo sapiens	54-58
26995112-6	2016	%FAME yield of 98.5%+-1.5 was achieved under the optimal conditions of catalyst/oil ratio of 5wt.%; methanol/oil molar ratio of 12:1; reaction temperature of 65 C; 10%v/v of THF in methanol and reaction time of 90min.	Methanol	100-108	benign adult familial myoclonic epilepsy 1	Homo sapiens	1-5
26995112-6	2016	%FAME yield of 98.5%+-1.5 was achieved under the optimal conditions of catalyst/oil ratio of 5wt.%; methanol/oil molar ratio of 12:1; reaction temperature of 65 C; 10%v/v of THF in methanol and reaction time of 90min.	Methanol	181-189	benign adult familial myoclonic epilepsy 1	Homo sapiens	1-5
27105156-3	2016	TR1 fraction from methanol extract showed the best antioxidant activity evaluated by the CUPRAC, RP and FRAP assays with TEAC values of 4.04, 1.77 and 1.48muM respectively compared to control.	Methanol	18-26	thioredoxin reductase 1	Homo sapiens	0-3
27105156-3	2016	TR1 fraction from methanol extract showed the best antioxidant activity evaluated by the CUPRAC, RP and FRAP assays with TEAC values of 4.04, 1.77 and 1.48muM respectively compared to control.	Methanol	18-26	mechanistic target of rapamycin kinase	Homo sapiens	104-108
27233360-2	2016	This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol extract against carbon tetrachloride (CCl4) provoked DNA damages and oxidative stress in kidneys of rat.	Methanol	81-89	C-C motif chemokine ligand 4	Rattus norvegicus	128-132
27145380-4	2016	This trihydride-tetrahydrideborate derivative and its PPh3 counterpart OsH3(kappa(2)-H2BH2)(IPr)(PPh3) (8) can be also obtained in a one-pot procedure, starting from 1 and 2 and using methanol at -60  C instead of 2-propanol as alcoholysis agent.	Methanol	184-192	protein phosphatase 4 catalytic subunit	Homo sapiens	97-101
26841777-10	2016	We propose that aerobic methane oxidation coupled to denitrification and perchlorate reduction (AMO-D and AMO-PR) directly oxidized methane and reduced NO3 (-) to NO2 (-) or N2O under anoxic condition, producing organic matter for methanol-assimilating denitrification and perchlorate reduction (MA-D and MA-PR) to reduce NO3 (-).	Methanol	231-239	NBL1, DAN family BMP antagonist	Homo sapiens	152-155
26512053-3	2016	CRH was analyzed using a radioimmunoassay and methanol extraction protocol.	Methanol	46-54	corticotropin releasing hormone	Homo sapiens	0-3
26963751-0	2016	Unique C-terminal region of Hap3 is required for methanol-regulated gene expression in the methylotrophic yeast Candida boidinii.	Methanol	49-57	Hap3p	Saccharomyces cerevisiae S288C	28-32
27389220-1	2016	The reductive conversion of CO2 into industrial products (e.g., oxalic acid, formic acid, methanol) can occur via aqueous CO2 (-) as a transient intermediate.	Methanol	90-98	complement C2	Homo sapiens	28-31
26923815-2	2016	Aiming at a better mechanistic understanding of methanol formation from CO2/H2 on highly selective supported Au/ZnO catalysts we have investigated the role of CO in the reaction process using isotope labelling experiments.	Methanol	48-56	complement C2	Homo sapiens	72-78
26867205-1	2016	Polymeric sheets of poly (methylmethaclyerate) (PMMA) containing charge transfer (CT) complex of rhodamine B/chloranilic acid (Rho B/CHA) were synthesized in methanol solvent at room temperature.	Methanol	158-166	ras homolog family member B	Homo sapiens	97-136
26593590-1	2016	The aim of this study was to evaluate the role of glucose transporter-4 (GLUT4) in the anti-diabetic effects of methanol, hexane and dichloromethane extracts of the aerial parts of Ocimum basilicum (OB) and to analyze their phytochemical composition.	Methanol	112-120	solute carrier family 2 member 4	Rattus norvegicus	73-78
27162558-7	2016	A kinetic study on sTCO diastereomers in 55:45 MeOH:water showed that the syn-diastereomer displayed slightly faster reactivity than the anti-diastereomer.	Methanol	47-51	synemin	Homo sapiens	74-77
26921118-2	2016	Propensity of the carbinol toward dehydration to yield the corresponding alkene, BMS-779788-ALK, was evaluated.	Methanol	18-26	ALK receptor tyrosine kinase	Homo sapiens	92-95
26767394-8	2016	Additionally, the compressive tests results confirmed that the methanol pre-treatment and the autoclaving step lead to an increase in the P2 secant modulus when compared to the non-methanol-treated ones, P2 and P5 (5% nanohydroxyapatite, 5% silk fibroin essence), respectively.Both formulations of polyhydroxybutyrate-polyhydroxyvalerate/nanohydroxyapatite/silk fibroin essence composite promoted greater cell adhesion and proliferation than the corresponding polyhydroxybutyrate-polyhydroxyvalerate control ones.	Methanol	63-71	protein phosphatase 5, catalytic subunit	Mus musculus	204-213
26836260-4	2016	Laboratory experiments validated the theoretical predictions, and by employing 2% MeOH/toluene as solvent, the Heck-Matsuda reaction provided exclusively the cis-4-arylcyclopentenols 3a-l in good to excellent yields in enantiomeric excesses up to 99%.	Methanol	82-86	suppressor of cytokine signaling 6	Homo sapiens	158-163
27011768-5	2016	RESULTS: A panel of active centromere protein antibodies was tested and we found that a rabbit monoclonal antibody against human CENP-C recognises the active centromeres of cells fixed in methanol-acetic acid.	Methanol	188-196	centromere protein C	Homo sapiens	129-135
26864530-12	2016	For samples where methanol is prevalent, combining SPE and MCM is more effective than the use of SPE alone.	Methanol	18-26	methylmalonyl-CoA mutase	Homo sapiens	59-62
26956043-4	2016	METHODS: Three cycloartanes OP3, OP5 and OP6 obtained by successive chromatography of the crude methanol extract of the leaves were hydrolysed to yield respective aglycone AOP1, AOP2, AOP3 and acetylated to HOP1, HOP2 and HOP3 respectively.	Methanol	96-104	bone morphogenetic protein 8b	Mus musculus	28-31
26956043-4	2016	METHODS: Three cycloartanes OP3, OP5 and OP6 obtained by successive chromatography of the crude methanol extract of the leaves were hydrolysed to yield respective aglycone AOP1, AOP2, AOP3 and acetylated to HOP1, HOP2 and HOP3 respectively.	Methanol	96-104	peroxiredoxin 3	Mus musculus	172-176
25726414-3	2016	MeOH exposure upregulated p22phox mRNA and protein expression, and enhanced protein oxidation, within 3-6 h. Compared to embryos exposed to MeOH alone, PBN and DPI pretreatment decreased MeOH-enhanced p22phox mRNA expression, DPI but not PBN blocked p22phox protein expression, and both blocked protein oxidation.	Methanol	0-4	cytochrome b-245, alpha polypeptide	Mus musculus	26-33
26967065-7	2016	Furthermore, we report protocols to detect Flag-tagged exogenous CENP-A proteins in human cells subjected to acetone or methanol fixation.	Methanol	120-128	centromere protein A	Homo sapiens	65-71
25726414-3	2016	MeOH exposure upregulated p22phox mRNA and protein expression, and enhanced protein oxidation, within 3-6 h. Compared to embryos exposed to MeOH alone, PBN and DPI pretreatment decreased MeOH-enhanced p22phox mRNA expression, DPI but not PBN blocked p22phox protein expression, and both blocked protein oxidation.	Methanol	0-4	cytochrome b-245, alpha polypeptide	Mus musculus	201-208
25726414-3	2016	MeOH exposure upregulated p22phox mRNA and protein expression, and enhanced protein oxidation, within 3-6 h. Compared to embryos exposed to MeOH alone, PBN and DPI pretreatment decreased MeOH-enhanced p22phox mRNA expression, DPI but not PBN blocked p22phox protein expression, and both blocked protein oxidation.	Methanol	0-4	cytochrome b-245, alpha polypeptide	Mus musculus	201-208
26551875-1	2016	The alcohols, methanol, ethylene glycol and diethylene glycol, have many features in common, the most important of which is the fact that the compounds themselves are relatively non-toxic but are metabolized, initially by alcohol dehydrogenase, to various toxic intermediates.	Methanol	14-22	aldo-keto reductase family 1 member A1	Homo sapiens	222-243
26862859-0	2016	Absorption intensity changes and frequency shifts of fundamental and first overtone bands for OH stretching vibration of methanol upon methanol-pyridine complex formation in CCl4: analysis by NIR/IR spectroscopy and DFT calculations.	Methanol	121-129	C-C motif chemokine ligand 4	Homo sapiens	174-178
26768840-1	2016	A new mesoporous silica based on the sol-gel material cyanopropyltriethoxysilane (CNPrTEOS) was successfully synthesized by the hydrolysis and condensation of CNPrTEOS in the presence of ammonium solution as catalyst and methanol as solvent.	Methanol	221-229	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	82-90
26980998-8	2016	In addition, the crude methanol extract and EtOAc strongly inhibited alpha-glucosidase activity and suppressed the secretion of pro-inflammatory mediator and nitrite oxide from LPS-stimulated RAW 264.7 cells.	Methanol	23-31	sucrase isomaltase (alpha-glucosidase)	Mus musculus	69-86
26862859-0	2016	Absorption intensity changes and frequency shifts of fundamental and first overtone bands for OH stretching vibration of methanol upon methanol-pyridine complex formation in CCl4: analysis by NIR/IR spectroscopy and DFT calculations.	Methanol	135-143	C-C motif chemokine ligand 4	Homo sapiens	174-178
26853854-4	2016	Addition of hydroperoxy radical precursors to the gas mixture (methanol and oxygen) subsequently led to a competition for photolytically generated Cl atoms and a simultaneous prompt formation of both ClO and HO2 radicals.	Methanol	63-71	heme oxygenase 2	Homo sapiens	208-211
26790573-1	2016	A bismuth-based metal-organic framework (MOF), [Bi(BTC)(H2O)] 2H2O MeOH denoted CAU-17, was synthesized and found to have an exceptionally complicated structure with helical Bi-O rods cross-linked by 1,3,5-benzenetricarboxylate (BTC(3-)) ligands.	Methanol	67-71	lysine acetyltransferase 8	Homo sapiens	16-46
26663080-0	2016	Regulation of Acetate Metabolism and Acetyl Co-a Synthetase 1 (ACS1) Expression by Methanol Expression Regulator 1 (Mxr1p) in the Methylotrophic Yeast Pichia pastoris.	Methanol	83-91	acetate--CoA ligase 1	Saccharomyces cerevisiae S288C	63-67
26663080-0	2016	Regulation of Acetate Metabolism and Acetyl Co-a Synthetase 1 (ACS1) Expression by Methanol Expression Regulator 1 (Mxr1p) in the Methylotrophic Yeast Pichia pastoris.	Methanol	83-91	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	116-121
26741738-1	2016	We report the photoelectrochemical (PEC) oxidation of methanol on a rationally designed graphene-TiO2 nanorod array (G-TNR) photoanode.	Methanol	54-62	tenascin R	Homo sapiens	119-122
26663080-1	2016	Methanol expression regulator 1 (Mxr1p) is a zinc finger protein that regulates the expression of genes encoding enzymes of the methanol utilization pathway in the methylotrophic yeast Pichia pastoris by binding to Mxr1p response elements (MXREs) present in their promoters.	Methanol	0-8	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	33-38
26741738-2	2016	A PEC methanol fuel cell was constructed by coupling the G-TNR photoanode with a cathode.	Methanol	6-14	tenascin R	Homo sapiens	59-62
26663080-1	2016	Methanol expression regulator 1 (Mxr1p) is a zinc finger protein that regulates the expression of genes encoding enzymes of the methanol utilization pathway in the methylotrophic yeast Pichia pastoris by binding to Mxr1p response elements (MXREs) present in their promoters.	Methanol	0-8	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	215-220
26663080-1	2016	Methanol expression regulator 1 (Mxr1p) is a zinc finger protein that regulates the expression of genes encoding enzymes of the methanol utilization pathway in the methylotrophic yeast Pichia pastoris by binding to Mxr1p response elements (MXREs) present in their promoters.	Methanol	128-136	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	33-38
26663080-1	2016	Methanol expression regulator 1 (Mxr1p) is a zinc finger protein that regulates the expression of genes encoding enzymes of the methanol utilization pathway in the methylotrophic yeast Pichia pastoris by binding to Mxr1p response elements (MXREs) present in their promoters.	Methanol	128-136	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	215-220
26663080-11	2016	The fact that MXREs are conserved in genes outside of the methanol utilization pathway suggests that Mxr1p may be a key regulator of multiple metabolic pathways in P. pastoris.	Methanol	58-66	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	101-106
26377232-4	2016	We found a dose- and time-dependent growth inhibition in human prostate cancer cells, PC3 and LNCaP, and mouse prostate cancer cell, TRAMP-C2, treated with S. frutescens methanol extract (SLE).	Methanol	170-178	translocating chain-associating membrane protein 1	Mus musculus	133-138
26734810-5	2016	As examples, the rhodium-catalyzed methanol carbonization, the Diels-Alder reaction between 1,3-butadiene and ethene, and the rearrangement of HCN to CNH are discussed.	Methanol	35-43	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	143-146
26304417-3	2016	The isomerized permeate was subsequently purified to a lactulose-rich product (LRP;   70% lactulose content to total sugar) through crystallizing lactose out by methanol.	Methanol	161-169	LDL receptor related protein 1	Homo sapiens	79-82
26593327-3	2016	The macrocycles bind anions that were once considered too weak to be coordinated, such as PF6 (-) , with surprisingly high affinities (beta2 =10(11)  M(-2) in 80:20 chloroform/methanol) and positive cooperativity, alpha=(4 K2 /K1 )=1200.	Methanol	176-184	sperm associated antigen 17	Homo sapiens	90-93
26680663-1	2016	The synthetic peptide Z-(Aib)10-OH was crystallized from hot methanol by slow evaporation.	Methanol	61-69	ANIB1	Homo sapiens	25-28
26893742-10	2016	The IC50 values obtained for the PC3 cell line were 37.97+-3.87, 51.57+-3.87 and 70.33+-2.36 for the CH2Cl2 fraction, the EtOAc fraction and the methanol extract, respectively.	Methanol	145-153	chromobox 8	Homo sapiens	33-36
26809818-5	2016	SDS-PAGE and Western blotting assays using the culture media from methanol-induced expression strains showed that recombinant CD40-N, a 27 kDa glycosylated protein, was secreted into the culture broth.	Methanol	66-74	CD40 molecule	Homo sapiens	126-130
26652192-4	2016	The surface-modified membrane, when used with chloroform-based solvent, exhibited superb permeate flux, breakthrough pressure, and also separation yield: it allowed separation of 95.5 +- 1.2% of converted lipid (FAME) in the chloroform phase from the water/MeOH phase with microalgal debris.	Methanol	257-261	benign adult familial myoclonic epilepsy 1	Homo sapiens	212-216
26915245-6	2016	Fomepizole is the antidote for methanol and ethyleneglycol, blocking alcohol dehydrogenase.	Methanol	31-39	aldo-keto reductase family 1 member A1	Homo sapiens	69-90
26298679-8	2016	One PDI analogue (the one formed from Tyr) in Methanol, however, appears to form J-type aggregates.	Methanol	46-54	peptidyl arginine deiminase 1	Homo sapiens	4-7
26593327-3	2016	The macrocycles bind anions that were once considered too weak to be coordinated, such as PF6 (-) , with surprisingly high affinities (beta2 =10(11)  M(-2) in 80:20 chloroform/methanol) and positive cooperativity, alpha=(4 K2 /K1 )=1200.	Methanol	176-184	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	135-140
27640395-2	2016	Reaction of H2L, kojic acid (5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one; Hka) and VO(acac)2 in methanol afforded a novel oxidovanadium(V) complex, [VO(ka)L].	Methanol	95-103	histocompatibility 2, D region locus L	Mus musculus	12-15
26678161-5	2016	Recombinant yeast transformants with high-level recombinant human IL-15 (rhIL-15) production were identified, which secrete as much as 75 mg/L rhIL-15 after 3 days of induction by methanol.	Methanol	180-188	interleukin 15	Homo sapiens	66-71
27904047-1	2016	The anti-osteoarthritic activity of the methanol fraction of deer bone oil extract (DBO-M) was evaluated in interleukin (IL)-1beta-inflamed primary rabbit chondrocytes and in rats with monosodium iodoacetate (MIA)-induced osteoarthritis.	Methanol	40-48	interleukin-1 beta	Oryctolagus cuniculus	108-130
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	aldo-keto reductase family 1 member A1	Rattus norvegicus	65-86
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interleukin 4	Rattus norvegicus	303-307
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	tumor necrosis factor	Rattus norvegicus	337-340
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interleukin 1 beta	Rattus norvegicus	342-347
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interferon gamma	Rattus norvegicus	349-358
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interleukin 4	Rattus norvegicus	360-364
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interleukin 2	Rattus norvegicus	366-370
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	0-8	interleukin 6	Rattus norvegicus	372-376
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	aldo-keto reductase family 1 member A1	Rattus norvegicus	65-86
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interleukin 4	Rattus norvegicus	303-307
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	tumor necrosis factor	Rattus norvegicus	337-340
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interleukin 1 beta	Rattus norvegicus	342-347
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interferon gamma	Rattus norvegicus	349-358
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interleukin 4	Rattus norvegicus	360-364
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interleukin 2	Rattus norvegicus	366-370
27455577-2	2016	Methanol antidote 4-methylpyrazole (non-competitive inhibitor of alcohol dehydrogenase) administered upon acute intoxication with methanol at a dose of 1.0 DL50 partially reduces the intoxication-induced suppression of humoral and cellular immune response, activity of T-helper cells, and production of IL-4 and restores blood levels of TNF, IL-1b, IFN-gamma, IL-4, IL-2, IL-6 to the control values.	Methanol	130-138	interleukin 6	Rattus norvegicus	372-376
27642356-0	2016	Traditional Preparations and Methanol Extracts of Medicinal Plants from Papua New Guinea Exhibit Similar Cytochrome P450 Inhibition.	Methanol	29-37	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	105-120
26855733-11	2016	Caspase assay and RT-PCR analysis revealed that brittle star methanol extract induced caspase dependent apoptosis in HeLa cells through up-regulation of caspase-3 followed by up-regulation of Bax gene which is a hallmark of intrinsic pathway recruitment.	Methanol	61-69	caspase 3	Homo sapiens	153-162
26855733-11	2016	Caspase assay and RT-PCR analysis revealed that brittle star methanol extract induced caspase dependent apoptosis in HeLa cells through up-regulation of caspase-3 followed by up-regulation of Bax gene which is a hallmark of intrinsic pathway recruitment.	Methanol	61-69	BCL2 associated X, apoptosis regulator	Homo sapiens	192-195
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	sucrase-isomaltase	Homo sapiens	129-146
26690232-1	2015	This paper examines polymer film morphology and several important properties of polyethylene-graft-sulfonated polyarylene ether sulfone (PE-g-s-PAES) proton exchange membranes (PEMs) for direct methanol fuel cell applications.	Methanol	194-202	progestagen associated endometrial protein	Homo sapiens	137-141
26690232-7	2015	Overall, the newly developed PE-g-s-PAES membranes offer a desirable set of PEM properties, including conductivity, selectivity, mechanical strength, stability, and cost-effectiveness for direct methanol fuel cell applications.	Methanol	195-203	progestagen associated endometrial protein	Homo sapiens	29-33
26568481-3	2015	We use several theoretical descriptors to categorize these species, focusing our attention on the interaction between the carbene carbon and the methanol oxygen, CcO, because this is the key interaction in the formation of O-ylides, ether products, and O-ylidic solvation complexes.	Methanol	145-153	ryanodine receptor 1	Homo sapiens	162-165
26690417-5	2015	The phenolic-rich methanol fraction of seed shell (SM) reduced nitric oxide (NO) production, and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.	Methanol	18-26	nitric oxide synthase 2, inducible	Mus musculus	97-128
26509744-0	2015	Visible-Light-Induced Direct Photocatalytic Carboxylation of Indoles with CBr4 /MeOH.	Methanol	80-84	carbonyl reductase 4	Homo sapiens	74-78
26509744-1	2015	Photocatalysis enables the cascade reactions of indoles and CBr4 in MeOH through a C(sp(2) ) H functionalization/methanolysis sequence.	Methanol	68-72	carbonyl reductase 4	Homo sapiens	60-64
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	148-179
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	181-186
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	acetylcholinesterase (Cartwright blood group)	Homo sapiens	189-209
25732977-16	2015	CONCLUSION: Administration of ethanol according to the present guidelines of the AACT/EAPCCT is effective and relatively safe in the treatment of methanol poisoning during a mass outbreak(31).	Methanol	146-154	serpin family A member 3	Homo sapiens	81-85
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	acetylcholinesterase (Cartwright blood group)	Homo sapiens	211-215
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	butyrylcholinesterase	Homo sapiens	222-243
26152875-4	2015	In the present study, we examined the inhibitory activity of methanol extracts of different parts of 12 Angelica species against alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE).	Methanol	61-69	butyrylcholinesterase	Homo sapiens	245-249
26152875-5	2015	The methanol extract of Angelica decursiva exhibited the highest inhibitory activities against alpha-glucosidase, PTP1B, AChE, and BChE and so was selected for further investigation.	Methanol	4-12	sucrase-isomaltase	Homo sapiens	95-112
26152875-5	2015	The methanol extract of Angelica decursiva exhibited the highest inhibitory activities against alpha-glucosidase, PTP1B, AChE, and BChE and so was selected for further investigation.	Methanol	4-12	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	114-119
26152875-5	2015	The methanol extract of Angelica decursiva exhibited the highest inhibitory activities against alpha-glucosidase, PTP1B, AChE, and BChE and so was selected for further investigation.	Methanol	4-12	acetylcholinesterase (Cartwright blood group)	Homo sapiens	121-125
26152875-5	2015	The methanol extract of Angelica decursiva exhibited the highest inhibitory activities against alpha-glucosidase, PTP1B, AChE, and BChE and so was selected for further investigation.	Methanol	4-12	butyrylcholinesterase	Homo sapiens	131-135
24898320-4	2015	We found that methanol extracts of teak, walnut, mahogany, and poplar dusts contained a wide range of AhR ligand activity, whereas extracts of oak, pine, and other softwoods did not contain appreciable activity.	Methanol	14-22	aryl hydrocarbon receptor	Homo sapiens	102-105
29861948-5	2015	Electro-catalytic oxygen reduction (ORR) and methanol oxidation (MOR) on these catalysts showed dramatic enhancements for both cathodic and anodic electrocatalysis in fuel cells, which were attributed to their unique morphology and crystalline structure, as well as synergetic effect of the multi-metallic components.	Methanol	45-53	opioid receptor mu 1	Homo sapiens	65-68
26143270-6	2015	The contribution of Co(III) to the bromate formation was verified with the addition of methanol and EDTA, a radical scavenger and a Co(III) ligand, respectively.	Methanol	87-95	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	20-26
26325200-0	2015	The effect of thermodynamic properties of solvent mixtures explains the difference between methanol and ethanol in C.antarctica lipase B catalyzed alcoholysis.	Methanol	91-99	PAN0_003d1715	Moesziomyces antarcticus	128-134
26377937-9	2015	We found that the methanol precipitation used to extract S1P co-extracted apoM and several other HDL-proteins from plasma.	Methanol	18-26	apolipoprotein M	Homo sapiens	74-78
26364226-2	2015	The nitrate removal rates obtained in the methanol- and ethanol-fed mixotrophic denitrifying AnFB-MBRs reached 1.44-3.84 g NO3 -N/L reactor d at a hydraulic retention time of 0.5 h, which were significantly superior to those reported in packed bed reactors.	Methanol	42-50	NBL1, DAN family BMP antagonist	Homo sapiens	123-126
26421324-2	2015	In aqueous solution, 2-thiophenone and 4-hydroxymethyl-1,3-dioxolan-2-one (HD) at a concentration of 2% by volume can increase the average charge of cytochrome c and myoglobin by up to 163%, resulting in even higher charge states than those that are produced from water/methanol/acid solutions in which these proteins are denatured.	Methanol	270-278	cytochrome c, somatic	Homo sapiens	149-161
26421324-2	2015	In aqueous solution, 2-thiophenone and 4-hydroxymethyl-1,3-dioxolan-2-one (HD) at a concentration of 2% by volume can increase the average charge of cytochrome c and myoglobin by up to 163%, resulting in even higher charge states than those that are produced from water/methanol/acid solutions in which these proteins are denatured.	Methanol	270-278	myoglobin	Homo sapiens	166-175
26143270-6	2015	The contribution of Co(III) to the bromate formation was verified with the addition of methanol and EDTA, a radical scavenger and a Co(III) ligand, respectively.	Methanol	87-95	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	23-26
26143270-7	2015	In the presence of methanol, free bromine formation increased with increasing Co(II) dosage but no bromate was detected, indicating that Co(III) oxidized bromide to form free bromine but not bromate.	Methanol	19-27	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	78-83
26143270-7	2015	In the presence of methanol, free bromine formation increased with increasing Co(II) dosage but no bromate was detected, indicating that Co(III) oxidized bromide to form free bromine but not bromate.	Methanol	19-27	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	137-143
26143270-8	2015	In the presence of both EDTA and methanol, no free bromine or bromate was detected, as Co(III) was stabilized by EDTA to form the Co(III)EDTA(-) complex, which could not oxidize bromide.	Methanol	33-41	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	87-94
26143270-8	2015	In the presence of both EDTA and methanol, no free bromine or bromate was detected, as Co(III) was stabilized by EDTA to form the Co(III)EDTA(-) complex, which could not oxidize bromide.	Methanol	33-41	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	90-93
26435899-5	2015	HCl gas in MeOH, provides C-protected beta(2,3) amino acids in excellent yields.	Methanol	11-15	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	38-46
26300122-3	2015	Herein, by combining time-resolved X-ray liquidography (TRXL) and time-resolved X-ray absorption spectroscopy (TR-XAS), we present strong evidence that the CHI2 radical is dominantly formed from the photolysis of CHI3 in methanol at 267 nm within the available time resolution of the techniques (~20 ps for TRXL and ~100 ps for TR-XAS).	Methanol	221-229	chitinase 1	Homo sapiens	213-217
26267352-6	2015	The TiO2 film increases the Faraday efficiency of methanol production by 5.7x to 4.79% under an applied potential of -0.6 V vs NHE, which is 1.3 V below the E(o)(CO2/CO2(-)) = -1.9 eV standard redox potential.	Methanol	50-58	solute carrier family 9 member C1	Homo sapiens	127-130
26102551-17	2015	Methanol and aqueous extracts increased the release of IFNgamma by PBMCs (p&lt;0.05); however, methanol extracts were significantly more active than aqueous extracts (p&lt;0.05).	Methanol	0-8	interferon gamma	Homo sapiens	55-63
26308773-4	2015	We report here crystal structures, cyclic voltammetry, UV-vis, IR, Raman, and (1)H NMR spectra for the complexes Rh2(esp)2L2 where L = pyridine, 3-picoline, 2,6-lutidine, acetonitrile, and methanol.	Methanol	189-197	Rh associated glycoprotein	Homo sapiens	113-116
26308773-6	2015	Taking these data into account we find that the strength of axial ligand binding to Rh2(esp)2 increases in the series CH3OH ~ 2,6-lutidine &lt; CH3CN &lt; 3-methylpyridine ~ pyridine.	Methanol	118-123	Rh associated glycoprotein	Homo sapiens	84-87
26798185-4	2015	Methanol extracts of Agastachis Herba were orally administered to the ovalbumin-induced asthmatic mice.	Methanol	0-8	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	70-79
26197032-1	2015	An unusual methylcyclopropanation from [2 + 1] cycloadditions of vinyl bromides to norbornenes catalyzed by Pd(OAc)2/PPh3 in the presence of CH3ONa and CH3OH has been established.	Methanol	152-157	caveolin 1	Homo sapiens	117-121
28911718-10	2015	When 7,9-diGS-DHP was irradiated in the presence of sodium azide (NaN3), the level of lipid peroxidation decreased; lipid peroxidation was enhanced when methanol was replaced by deuterated methanol.	Methanol	153-161	dihydropyrimidinase	Homo sapiens	14-17
25855560-8	2015	Methanol, fatty acids and/or lipids, glutamine, phenylalanine, starch, and nucleic acids were more abundant in eli1 than in WT.	Methanol	0-8	Cellulose synthase family protein	Arabidopsis thaliana	111-115
25961808-0	2015	Influence of a Counterion on the Ion Atmosphere of an Anion: A Molecular Dynamics Study of LiX and CsX (X = F(-), Cl(-), I(-)) in Methanol.	Methanol	130-138	NK2 homeobox 5	Homo sapiens	99-102
26208080-6	2015	Alcohol dehydrogenase (EC 1.1.1.1), able to catalyze the conversion of formaldehyde into methanol, was selected as the model enzyme.	Methanol	89-97	aldo-keto reductase family 1 member A1	Homo sapiens	0-21
26203595-1	2015	Using a multistep synthetic pathway, a bis(imino)pyridine (or pyridine diimine, PDI) molybdenum catalyst for the selective conversion of carbon dioxide into methanol has been developed.	Methanol	157-165	peptidyl arginine deiminase 1	Homo sapiens	80-83
26203595-11	2015	Notably, (kappa(6)-P,N,N,N,C,P-(Ph2PPr)PDI)MoH is the first Mo hydroboration catalyst capable of converting CO2 to MeOH, and the importance of this study as it relates to previously described catalysts is discussed.	Methanol	115-119	peptidyl arginine deiminase 1	Homo sapiens	39-42
26133429-10	2015	The SN2 reaction is dominated by events in which H2O leaves the reactive system as CH3OH is formed or before CH3OH formation.	Methanol	83-88	solute carrier family 38 member 5	Homo sapiens	4-7
26123176-4	2015	Subsequent experiments in embryos that had been chilled for 3 h in 1 M methanol and warmed and cultured up to the hatching stages found that sox2 and sox3 gene expression were increased significantly in hatched embryos that had been chilled compared to non-chilled controls.	Methanol	71-79	SRY-box transcription factor 2	Danio rerio	141-145
26197325-7	2015	The butanolic phase of the MeOH extract had the most potent inhibitory effects, reducing enzymatic activity and thrombin-induced plasma coagulation.	Methanol	27-31	coagulation factor II, thrombin	Homo sapiens	112-120
25891966-0	2015	CYP2E1 polymorphism and better outcome after methanol poisoning.	Methanol	45-53	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	0-6
25892090-0	2015	Response to "CYP2E1 polymorphism and better outcome after methanol poisoning".	Methanol	58-66	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	13-19
25919936-6	2015	Experimental results revealed the optimum FAME yield and oleic acid conversion of 91.3wt.% and 98.1wt.%, respectively were attained at 65 C for 5h with 5wt.% catalyst loading and 20:1 methanol to oleic acid molar ratio.	Methanol	184-192	benign adult familial myoclonic epilepsy 1	Homo sapiens	42-46
25702903-0	2015	Ameliorative effect of methanol extract of Rumex vesicarius on CCl4-induced liver damage in Wistar albino rats.	Methanol	23-31	C-C motif chemokine ligand 4	Rattus norvegicus	63-67
26233126-0	2015	Spin-torsion effects in the hyperfine structure of methanol.	Methanol	51-59	spindlin 1	Homo sapiens	0-4
26197325-9	2015	Chromatographic analyses of thrombin samples incubated with these flavonoids demonstrated the chemical modification of this enzyme, suggesting that the MeOH extract contained other compounds that both induced structural changes in thrombin and diminished its activity.	Methanol	152-156	coagulation factor II, thrombin	Homo sapiens	28-36
26197325-9	2015	Chromatographic analyses of thrombin samples incubated with these flavonoids demonstrated the chemical modification of this enzyme, suggesting that the MeOH extract contained other compounds that both induced structural changes in thrombin and diminished its activity.	Methanol	152-156	coagulation factor II, thrombin	Homo sapiens	231-239
26086090-2	2015	Reactions were carried out in a tubular flow reactor under pressures up to 42 bar at 830-910  C. Using a CH4 to steam to CO2 ratio of ~3:2:1 in the gas feed, the H2/CO ratio of 2:1 was achieved, which is desired for subsequent methanol synthesis.	Methanol	227-235	relaxin 2	Homo sapiens	162-180
25212570-0	2015	Down-regulation of Akt by methanol extracts of Impatiens balsamina L. promotes apoptosis in human oral squamous cell carcinoma cell lines.	Methanol	26-34	AKT serine/threonine kinase 1	Homo sapiens	19-22
25843356-6	2015	The maximum biodiesel yield was 100% for the base (KOH) catalyzed transesterification at 1:10M ratio of lipid to methanol in 2h at 60 C. Novozyme-435 yielded a 90% FAME conversion at 40 C and 1:5 lipid to methanol molar ratio in 24h.	Methanol	113-121	benign adult familial myoclonic epilepsy 1	Homo sapiens	164-168
25843356-6	2015	The maximum biodiesel yield was 100% for the base (KOH) catalyzed transesterification at 1:10M ratio of lipid to methanol in 2h at 60 C. Novozyme-435 yielded a 90% FAME conversion at 40 C and 1:5 lipid to methanol molar ratio in 24h.	Methanol	205-213	benign adult familial myoclonic epilepsy 1	Homo sapiens	164-168
25998829-3	2015	Furthermore, replacing the -Cl substituent with -Br on the HL-X ligand will also afford three diverse coordination assemblies of 3D {[Zn2(L-Br)4(H2O)](CH3OH)2.5}n (5), mononuclear [Zn(HL-Br)2(H2O)4][L-Br]2 (6), and 2D {[Zn(L-Br)2](H2O)1.15}n (7) depending on the synthetic pathways.	Methanol	151-156	H2.0 like homeobox	Homo sapiens	59-63
26133429-10	2015	The SN2 reaction is dominated by events in which H2O leaves the reactive system as CH3OH is formed or before CH3OH formation.	Methanol	109-114	solute carrier family 38 member 5	Homo sapiens	4-7
25575971-5	2015	Esterification of FFAs with methanol was catalysed by lipase Novozym 435 from Candida antarctica.	Methanol	28-36	PAN0_003d1715	Moesziomyces antarcticus	54-60
25974728-3	2015	In contrast, absorption of methanol and ethanol by 2 at 295 K led to structural transformation probably connected with coordination of these alcohols to Co(II).	Methanol	27-35	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	153-159
26124811-8	2015	CONCLUSION: Study conducted on Eriobotrya japonica shows that CH2Cl2/MeOH 0:1 fraction inhibits efficiently the hG-IIA phospholipase.	Methanol	69-73	glucosidase II alpha subunit	Homo sapiens	112-118
25739535-1	2015	Aryl chalcones rearrange and add methanol to give substituted propane-1-ones upon UV-A irradiation in the presence of PPh3.	Methanol	33-41	caveolin 1	Homo sapiens	118-122
25859815-6	2015	When the reaction of RuCl2(PPh3)3 with carbon disulfide is conducted in the presence of methanol, crystals of orange [RuCl(S2CPPh3)(CS)(PPh3)2]Cl 2MeOH and yellow RuCl2(CS)(MeOH)(PPh3)2 also form.	Methanol	88-96	protein phosphatase 4 catalytic subunit	Homo sapiens	27-31
25859815-6	2015	When the reaction of RuCl2(PPh3)3 with carbon disulfide is conducted in the presence of methanol, crystals of orange [RuCl(S2CPPh3)(CS)(PPh3)2]Cl 2MeOH and yellow RuCl2(CS)(MeOH)(PPh3)2 also form.	Methanol	88-96	protein phosphatase 4 catalytic subunit	Homo sapiens	126-130
25859815-6	2015	When the reaction of RuCl2(PPh3)3 with carbon disulfide is conducted in the presence of methanol, crystals of orange [RuCl(S2CPPh3)(CS)(PPh3)2]Cl 2MeOH and yellow RuCl2(CS)(MeOH)(PPh3)2 also form.	Methanol	88-96	protein phosphatase 4 catalytic subunit	Homo sapiens	126-130
25859815-6	2015	When the reaction of RuCl2(PPh3)3 with carbon disulfide is conducted in the presence of methanol, crystals of orange [RuCl(S2CPPh3)(CS)(PPh3)2]Cl 2MeOH and yellow RuCl2(CS)(MeOH)(PPh3)2 also form.	Methanol	147-151	protein phosphatase 4 catalytic subunit	Homo sapiens	27-31
26136894-8	2015	In addition, the methanol extract of PJ was found to inhibit the growth of Hep3B HCC cells through inhibiting the Akt/mTOR and Wnt signaling pathways.	Methanol	17-25	AKT serine/threonine kinase 1	Homo sapiens	114-117
26136894-8	2015	In addition, the methanol extract of PJ was found to inhibit the growth of Hep3B HCC cells through inhibiting the Akt/mTOR and Wnt signaling pathways.	Methanol	17-25	mechanistic target of rapamycin kinase	Homo sapiens	118-122
25698375-3	2015	Such co-immobilization and sequential immobilization systems were examined for the production of methanol from CO2 with formate dehydrogenase (FDH), formaldehyde dehydrogenase (FaldDH) and alcohol dehydrogenase (ADH).	Methanol	97-105	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	149-175
25698375-3	2015	Such co-immobilization and sequential immobilization systems were examined for the production of methanol from CO2 with formate dehydrogenase (FDH), formaldehyde dehydrogenase (FaldDH) and alcohol dehydrogenase (ADH).	Methanol	97-105	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	177-183
25698375-3	2015	Such co-immobilization and sequential immobilization systems were examined for the production of methanol from CO2 with formate dehydrogenase (FDH), formaldehyde dehydrogenase (FaldDH) and alcohol dehydrogenase (ADH).	Methanol	97-105	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	212-215
25832847-1	2015	The diethyl ester of o-phenylenebis(oxamic acid) (opbaH2Et2) was treated with an excess of RNH2 in MeOH to cause the exclusive formation of the respective o-phenylenebis(N(R)-oxamides) (opboH4R2, R = Me , Et , (n)Pr ) in good yields.	Methanol	99-103	NLR family pyrin domain containing 4	Homo sapiens	91-95
26180273-7	2015	On the other hand, methanol and acetonitrile at concentrations &lt;0.5% v/v appeared to be appropriate solvents for substrate solubilization while evaluating CYP2E1-mediated catalysis.	Methanol	19-27	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	158-164
26229223-0	2015	BAX/BCL-2 mRNA and protein expression in human breast MCF-7 cells exposed to drug vehicles-methanol and dimethyl sulfoxide (DMSO) for 24 hrs.	Methanol	91-99	BCL2 associated X, apoptosis regulator	Homo sapiens	0-3
26229223-0	2015	BAX/BCL-2 mRNA and protein expression in human breast MCF-7 cells exposed to drug vehicles-methanol and dimethyl sulfoxide (DMSO) for 24 hrs.	Methanol	91-99	BCL2 apoptosis regulator	Homo sapiens	4-9
26229223-6	2015	Gene expression and Immunofluorescence results showed that methanol but not DMSO reduced the expression of the BAX pro-apoptotic protein, while both solvents did not alter the expression of the BCL-2 oncoprotein.	Methanol	59-67	BCL2 associated X, apoptosis regulator	Homo sapiens	111-114
26109759-8	2015	In silico docking interaction of the 14 active components (identified by high-performance liquid chromatography/gas chromatography-mass spectroscopy) of the methanol extract was tested with cyclin D1 (Protein Data Bank ID: 2W96) and compared with the reference cyclin D1/Cdk4 inhibitor.	Methanol	157-165	cyclin D1	Homo sapiens	190-199
26109759-8	2015	In silico docking interaction of the 14 active components (identified by high-performance liquid chromatography/gas chromatography-mass spectroscopy) of the methanol extract was tested with cyclin D1 (Protein Data Bank ID: 2W96) and compared with the reference cyclin D1/Cdk4 inhibitor.	Methanol	157-165	cyclin D1	Homo sapiens	261-270
26109759-8	2015	In silico docking interaction of the 14 active components (identified by high-performance liquid chromatography/gas chromatography-mass spectroscopy) of the methanol extract was tested with cyclin D1 (Protein Data Bank ID: 2W96) and compared with the reference cyclin D1/Cdk4 inhibitor.	Methanol	157-165	cyclin dependent kinase 4	Homo sapiens	271-275
25723373-6	2015	Some enzymes (dehydrogenases, oxidase, and catalase) are valuable products with high conversion efficiencies and can generate methanol or sequester CO2 as formic acid ex vivo.	Methanol	126-134	catalase	Homo sapiens	30-51
26109759-13	2015	CONCLUSION: These findings indicate that the methanol extract of wheatgrass inhibits human laryngeal cancer cell proliferation via cell cycle G1 arrest and p53 induction.	Methanol	45-53	tumor protein p53	Homo sapiens	156-159
27774417-5	2016	Methanol extract of Green tea and commercially purchased EGCG (&gt;95 % purity) were tested in vitro for their ability to inhibit MMP-9 activity and/or its release from neutrophils using a beta-casein cleavage assay and gelatin zymography, respectively.	Methanol	0-8	matrix metallopeptidase 9	Homo sapiens	130-135
25825923-4	2015	The subsequent RE-1,4-NDC-fcu-MOF structural features, contracted windows/pores and high concentration of open metal sites combined with exceptional hydrothermal and chemical stabilities, yielded notable gas/solvent separation properties, driven mostly by adsorption kinetics as exemplified in this work for n-butane/methane, butanol/methanol, and butanol/water pair systems.	Methanol	334-342	lysine acetyltransferase 8	Homo sapiens	30-33
25772403-1	2015	The weak interaction between PCl3 and CH3OH was investigated using matrix isolation infrared spectroscopy and ab initio computations.	Methanol	38-43	PHD finger protein 19	Homo sapiens	29-33
25770621-3	2015	After centrifugation, the separated methanol was diluted to 50 mL with double-distillated water and passed through the C18 SPE cartridge.	Methanol	36-44	Bardet-Biedl syndrome 9	Homo sapiens	119-122
26989740-10	2015	In addition, VEGF and b-FGF expression decreased with brittle star methanol extract treatment.	Methanol	67-75	vascular endothelial growth factor A	Homo sapiens	13-17
26164908-2	2015	The experiments results showed gamma irradiation could effectively remove ciprofloxacin hydrochloride; low initial concentration and strongly acidic condition were favorable for CIP removal using gamma irradiation; the degradation of CIP was inhibited upon the addition of CO3(2-) and methanol, which indicated that the degradation of CIP might be mainly ascribed to *OH oxidation and the direct decomposition of CIP molecules induced by irradiation.	Methanol	285-293	muscular LMNA interacting protein	Homo sapiens	234-237
26164908-2	2015	The experiments results showed gamma irradiation could effectively remove ciprofloxacin hydrochloride; low initial concentration and strongly acidic condition were favorable for CIP removal using gamma irradiation; the degradation of CIP was inhibited upon the addition of CO3(2-) and methanol, which indicated that the degradation of CIP might be mainly ascribed to *OH oxidation and the direct decomposition of CIP molecules induced by irradiation.	Methanol	285-293	muscular LMNA interacting protein	Homo sapiens	234-237
26989740-10	2015	In addition, VEGF and b-FGF expression decreased with brittle star methanol extract treatment.	Methanol	67-75	fibroblast growth factor 2	Homo sapiens	22-27
25612313-6	2015	The transduction mechanism for the biosensor was based on AOx-catalyzed oxidation of methanol to produce hydrogen peroxide.	Methanol	85-93	acyl-CoA oxidase 1	Homo sapiens	58-61
25207794-1	2015	Frozen core MP2 and DFT computations were carried out on possible configurations of 1:1 H2SO4 CH3OH and 1:1:1 H2SO4 CH3OH H2O complexes.	Methanol	94-99	tryptase pseudogene 1	Homo sapiens	12-15
25621533-2	2015	HO2, H2O2, and H2CO were generated from the oxidation of methanol initiated by pulsed-laser-photolysis of Cl2 in a low-pressure slow flow reactor.	Methanol	57-65	heme oxygenase 2	Homo sapiens	0-3
25782036-6	2015	The number of amyloid-beta aggregates decreased by 30% after treatment with isoliquiritigenin, the methanol extract could reduce the number by 14%, liquiritigenin and glycyrrhizic acid by 15%, and the aglycon of glycyrrhizic acid, glycyrrhetinic acid, by 20%.	Methanol	99-107	amyloid beta precursor protein	Homo sapiens	14-26
25679337-1	2015	The crude methanol extract of Pueraria lobata was investigated by dual high-resolution alpha-glucosidase inhibition and radical scavenging profiling combined with hyphenated HPLC-HRMS-SPE-NMR.	Methanol	10-18	sucrase-isomaltase	Homo sapiens	87-104
25266591-8	2015	Stimulating simultaneous heterotrophic and autotrophic denitrification by dozing methanol increased denitrification rate up to 0.72 g NO3 (-)-N/(L day), decreased alkalinity requirement, and reduced sulfate generation.	Methanol	81-89	NBL1, DAN family BMP antagonist	Homo sapiens	134-137
25490561-3	2015	The addition of water had only a minor effect on the liquid crystal structures, however methanol had a significant effect, which was attributed to methanol being a good solvent for both the PEO and PPO blocks of the polymer.	Methanol	88-96	protoporphyrinogen oxidase	Homo sapiens	198-201
25490561-3	2015	The addition of water had only a minor effect on the liquid crystal structures, however methanol had a significant effect, which was attributed to methanol being a good solvent for both the PEO and PPO blocks of the polymer.	Methanol	147-155	protoporphyrinogen oxidase	Homo sapiens	198-201
25625202-2	2015	To better understand these phenomena we calculate spatially resolved thermodynamic contributions of the different molecular degrees of freedom for the binding of propane and methanol to multiple pockets on the proteins Factor Xa and p38 MAP kinase.	Methanol	174-182	coagulation factor X	Homo sapiens	219-228
25625202-2	2015	To better understand these phenomena we calculate spatially resolved thermodynamic contributions of the different molecular degrees of freedom for the binding of propane and methanol to multiple pockets on the proteins Factor Xa and p38 MAP kinase.	Methanol	174-182	mitogen-activated protein kinase 14	Homo sapiens	233-236
27682076-3	2015	C-1 compounds such as methane and methanol are important intermediates in the deep subsurface carbon cycle, and electron acceptors such as sulphate are critical components of oxidation processes.	Methanol	34-42	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	0-3
25598494-3	2015	A two order-of-magnitude of activation for the methanol substitution is induced as manifested by the second order rate constants with (N,N"-Bid) &lt; (N,O-Bid).	Methanol	47-55	BH3 interacting domain death agonist	Homo sapiens	140-143
25598494-3	2015	A two order-of-magnitude of activation for the methanol substitution is induced as manifested by the second order rate constants with (N,N"-Bid) &lt; (N,O-Bid).	Methanol	47-55	BH3 interacting domain death agonist	Homo sapiens	155-158
25604356-2	2015	These complexes are described as [Co(III)(L(X))MeOH], where X indicates the presence of chloro (), bromo (), iodo (), or tert-butyl () substituents in the 3(rd) and 5(th) positions of each phenolate ring.	Methanol	47-51	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	34-41
25573414-3	2015	The probe, termed BOB, has two absorption maxima (lambdaabs = 426 and 561 nm) and two emission maxima--a strong green emission (lambdaem = 467 nm) and a weak red emission (642 nm in methanol)--when excited at 405 nm.	Methanol	182-190	G protein-coupled receptor 15	Homo sapiens	18-21
25653022-0	2015	Sargassum horneri methanol extract rescues C2C12 murine skeletal muscle cells from oxidative stress-induced cytotoxicity through Nrf2-mediated upregulation of heme oxygenase-1.	Methanol	18-26	nuclear factor, erythroid derived 2, like 2	Mus musculus	129-133
25653022-0	2015	Sargassum horneri methanol extract rescues C2C12 murine skeletal muscle cells from oxidative stress-induced cytotoxicity through Nrf2-mediated upregulation of heme oxygenase-1.	Methanol	18-26	heme oxygenase 1	Mus musculus	159-175
25311520-1	2015	The interaction of Cd(II) with the non-steroidal anti-inflammatory drug diclofenac sodium (Dic) leads to the formation of the complex [Cd2(L)41.5(MeOH)2(H2O)]n(L = Dic), 1, which has been isolated and structurally characterized by X-ray crystallography.	Methanol	146-150	CD2 molecule	Homo sapiens	135-138
24315445-1	2015	The reactions of Co(II) sources with N-salicylidene-o-aminophenol (H2saph), N-salicylidene-o-amino-4-methylphenol (H2saph-4Me) and N-salicylidene-o-amino-4-chlorophenol (H2saph-4Cl) were studied in MeOH.	Methanol	198-202	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	17-22
25311520-1	2015	The interaction of Cd(II) with the non-steroidal anti-inflammatory drug diclofenac sodium (Dic) leads to the formation of the complex [Cd2(L)41.5(MeOH)2(H2O)]n(L = Dic), 1, which has been isolated and structurally characterized by X-ray crystallography.	Methanol	146-150	dynein axonemal intermediate chain 1	Homo sapiens	164-171
25545702-3	2015	Significant decreases in sox3 gene expression were observed in hatched embryos that had been chilled for 18 h in 1 M MeOH+0.1 sucrose compared with non-chilled controls, however the expression of both sox2 and sox3 proteins was unaffected.	Methanol	117-121	SRY-box transcription factor 3	Danio rerio	25-29
25146350-0	2015	Rare alleles within the CYP2E1 (MEOS system) could be associated with better short-term health outcome after acute methanol poisoning.	Methanol	115-123	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	24-30
25146350-6	2015	Variants within the CYP2E1 gene are likely not significant genetic determinants of acute methanol poisoning (if survivors are analysed), but they may influence the severity of methanol poisoning and its visual/central nervous system (CNS) outcome.	Methanol	176-184	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	20-26
25462307-8	2015	A C-H bond of the methoxyl is activated by Compound I, followed by radical rebound to form carbinol intermediates, then the carbinols decompose to form 6-HO-BDE-47 with the assistance of water molecules.	Methanol	91-99	homeobox D13	Homo sapiens	157-160
25462307-8	2015	A C-H bond of the methoxyl is activated by Compound I, followed by radical rebound to form carbinol intermediates, then the carbinols decompose to form 6-HO-BDE-47 with the assistance of water molecules.	Methanol	124-133	homeobox D13	Homo sapiens	157-160
25147102-2	2015	For the folding process, a beta-hexapeptide that adopts, as inferred from NMR experiments, both a right-handed 2.710/12-helical fold and a left-handed 314-helical fold in methanol, is used to illustrate the challenge of modeling thermodynamically driven processes at different levels of resolution.	Methanol	171-179	amyloid beta precursor protein	Homo sapiens	25-31
25878826-1	2015	The crystal structures of two solvates of fac-tri-chlorido-tris-(tri-methyl-phosphane-kappaP)rhodium(III) are reported, i.e. one with water in the crystal lattice, fac-[RhCl3(Me3P)3] H2O, and one with methanol in the crystal lattice, fac-[RhCl3(Me3P)3] 0.5CH3OH.	Methanol	201-209	FA complementation group C	Homo sapiens	42-45
26050816-2	2015	Kv1.5 and Kv4.2 at intercalated discs and Cav1.2 at transverse tubules were not detected by FA but were detected by MeOH.	Methanol	116-120	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	0-5
25446176-5	2015	CP 2 was reversibly transformed to 3 by the addition of methanol and heat.	Methanol	56-64	ceruloplasmin	Homo sapiens	0-4
25600201-7	2015	The results showed significant time-dependent inhibition of tested samples on CYP3A4 with crude methanol (39KC), fractions 45A, 45B and 45D given IC50 fold decrease of 3.29, 2.26, 1.91 and 1.49, respective.	Methanol	96-104	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-84
25600201-11	2015	At least one phytoconstituent in the crude methanol extract of Kalanchoe crenata is a reversible and time-dependent inhibitor of CYP3A4.	Methanol	43-51	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	129-135
25446595-4	2015	The therapeutic effects of raw Heshouwu on aging-related diseases were somehow similar to the anti-aging effects of growth hormone release induced by ghrelin MATERIALS AND METHODS: Major ingredients in the methanol extract from raw Heshouwu were separated and identified.	Methanol	206-214	gonadotropin releasing hormone receptor	Rattus norvegicus	116-130
25446595-4	2015	The therapeutic effects of raw Heshouwu on aging-related diseases were somehow similar to the anti-aging effects of growth hormone release induced by ghrelin MATERIALS AND METHODS: Major ingredients in the methanol extract from raw Heshouwu were separated and identified.	Methanol	206-214	ghrelin and obestatin prepropeptide	Rattus norvegicus	150-157
26381032-2	2015	Recently, we showed that a methanol extract of Phyllanthaceae (Pa-ME) has a potent anti-inflammatory activity in RAW264.7 cells and strongly ameliorates HCl / EtOH -induced gastric ulcers in mice by targeting the Src/Syk of NF-kappaB.	Methanol	27-35	Rous sarcoma oncogene	Mus musculus	213-216
26381032-2	2015	Recently, we showed that a methanol extract of Phyllanthaceae (Pa-ME) has a potent anti-inflammatory activity in RAW264.7 cells and strongly ameliorates HCl / EtOH -induced gastric ulcers in mice by targeting the Src/Syk of NF-kappaB.	Methanol	27-35	spleen tyrosine kinase	Mus musculus	217-220
26381032-2	2015	Recently, we showed that a methanol extract of Phyllanthaceae (Pa-ME) has a potent anti-inflammatory activity in RAW264.7 cells and strongly ameliorates HCl / EtOH -induced gastric ulcers in mice by targeting the Src/Syk of NF-kappaB.	Methanol	27-35	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	224-233
26557712-3	2015	Herein, a crude methanol extract was prepared from Fenugreek seeds (FCE) and its anticancer mechanism was evaluated, using HepG2 cell line.	Methanol	16-24	ferrochelatase	Homo sapiens	68-71
25214228-2	2015	PRC1 coding for proteinase C from Saccharomyces cerevisiae was expressed in Pichia pastoris GS115 as procarboxypeptidase Y with a yield of ~605 mg/l in shake-flasks after 168 h induction with 1 % (v/v) methanol.	Methanol	202-210	carboxypeptidase C PRC1	Saccharomyces cerevisiae S288C	0-4
30154993-4	2015	A detailed mechanistic study using DFT calculations shows that a sequential series of hydride transfer and protonolysis steps can account for the transformation of CO2via formate/formic acid to hydroxymethanolate/formaldehyde and finally methanolate/methanol within the coordination sphere of a single Ru-Triphos-fragment.	Methanol	201-209	complement C2	Homo sapiens	164-167
26050816-2	2015	Kv1.5 and Kv4.2 at intercalated discs and Cav1.2 at transverse tubules were not detected by FA but were detected by MeOH.	Methanol	116-120	potassium voltage-gated channel subfamily D member 2	Rattus norvegicus	10-15
26161806-2	2015	This study was designed to determine the presence of hormone-like activities dependent on the activation of human estrogen receptor alpha (hERa) and/or androgen receptor (hAR) in methanol extracts prepared from three medicinal plants historically and currently used for therapeutic purposes: Ginkgo biloba leaves (GBL), Elettaria cardamomum seeds (ECS) and Plantago ovata seeds (POS).	Methanol	179-187	estrogen receptor 1	Homo sapiens	114-137
24934969-3	2014	A PLS-2 model was established for simultaneous determination of the studied pollutants in methanol, by using twenty mixtures as calibration set and five mixtures as validation set.	Methanol	90-98	lymphocyte cytosolic protein 1	Homo sapiens	2-7
26161806-2	2015	This study was designed to determine the presence of hormone-like activities dependent on the activation of human estrogen receptor alpha (hERa) and/or androgen receptor (hAR) in methanol extracts prepared from three medicinal plants historically and currently used for therapeutic purposes: Ginkgo biloba leaves (GBL), Elettaria cardamomum seeds (ECS) and Plantago ovata seeds (POS).	Methanol	179-187	Era like 12S mitochondrial rRNA chaperone 1	Homo sapiens	139-143
26161806-2	2015	This study was designed to determine the presence of hormone-like activities dependent on the activation of human estrogen receptor alpha (hERa) and/or androgen receptor (hAR) in methanol extracts prepared from three medicinal plants historically and currently used for therapeutic purposes: Ginkgo biloba leaves (GBL), Elettaria cardamomum seeds (ECS) and Plantago ovata seeds (POS).	Methanol	179-187	androgen receptor	Homo sapiens	152-169
26161806-2	2015	This study was designed to determine the presence of hormone-like activities dependent on the activation of human estrogen receptor alpha (hERa) and/or androgen receptor (hAR) in methanol extracts prepared from three medicinal plants historically and currently used for therapeutic purposes: Ginkgo biloba leaves (GBL), Elettaria cardamomum seeds (ECS) and Plantago ovata seeds (POS).	Methanol	179-187	lymphatic vessel endothelial hyaluronan receptor 1	Homo sapiens	171-174
26155726-2	2015	In this perspective, the methanol extract and HTMF are shown to demonstrate prominent inhibitory activity against soybean lipoxygenase, with an IC50 value of 21.12 and 23.97 microg/ml, respectively.	Methanol	25-33	linoleate 9S-lipoxygenase-4	Glycine max	122-134
25333888-9	2015	In conclusion, to the best of our knowledge, the present study is the first to show that a methanol extract of AC stimulates melanogenesis by increasing tyrosinase expression via the inhibition of ERK and Akt.	Methanol	91-99	thymoma viral proto-oncogene 1	Mus musculus	205-208
25243876-2	2015	OBJECTIVE: The current research investigated the protective effect of the methanol extract of N. biserrata leaves against carbon tetrachloride (CCl4)-induced hepatic damage in rats.	Methanol	74-82	C-C motif chemokine ligand 4	Rattus norvegicus	144-148
26738360-5	2015	RESULTS: The methanol extract of Salvia trichoclada showed the highest inhibition on AChE.	Methanol	13-21	acetylcholinesterase	Cavia porcellus	85-89
25580392-7	2014	The MeOH extracts of RK and GK exhibited potent inhibitory activities against PTP1B with the corresponding IC50 values of 207+-3.48 and 287+-3.22 mug/mL, respectively.	Methanol	4-8	protein tyrosine phosphatase, non-receptor type 1	Rattus norvegicus	78-83
25213563-3	2014	RS-N shows selective color change from colorless to pink in the presence of Hg(2+) in methanol/water solvent and the UV-Vis study shows peak at 560 nm.	Methanol	86-94	CAP-Gly domain containing linker protein 1	Homo sapiens	0-4
25834514-10	2014	Treatment with 800mg/kg body weight of methanol leaf extract significantly decreased body, liver and kidney weights, red blood cells (RBC), haemoglobin (Hgb), mean cell haemoglobin (Mch), Mchc, platelet and significantly increased serum aspartate transferance (AST), vatanine tranferance(ALT) and alkaline phosphate (ALP) levels while 400mg/kg dose had no effect on these parameters.	Methanol	39-47	modifier of chinchilla	Mus musculus	182-185
25834514-10	2014	Treatment with 800mg/kg body weight of methanol leaf extract significantly decreased body, liver and kidney weights, red blood cells (RBC), haemoglobin (Hgb), mean cell haemoglobin (Mch), Mchc, platelet and significantly increased serum aspartate transferance (AST), vatanine tranferance(ALT) and alkaline phosphate (ALP) levels while 400mg/kg dose had no effect on these parameters.	Methanol	39-47	glutamic pyruvic transaminase, soluble	Mus musculus	288-291
25834514-15	2014	CONCLUSION: This study suggests that the methanol leaf extract may have been phytotoxic to liver that resulted in a rise in serum AST, ALT and ALP levels.	Methanol	41-49	glutamic pyruvic transaminase, soluble	Mus musculus	135-138
25314333-2	2014	Rapid formation of the catalytically active solvent-coordinated hydride species [(dadpx)PdH(MeOH)](+) (3-MeOH) is evidenced by NMR spectroscopy, and further isolation and X-ray crystal structure analysis of [(dadpx)PdH(PPh3 )](+) (3-PPh3 ).	Methanol	92-96	pyruvate dehydrogenase phosphatase catalytic subunit 1	Homo sapiens	88-91
25314333-2	2014	Rapid formation of the catalytically active solvent-coordinated hydride species [(dadpx)PdH(MeOH)](+) (3-MeOH) is evidenced by NMR spectroscopy, and further isolation and X-ray crystal structure analysis of [(dadpx)PdH(PPh3 )](+) (3-PPh3 ).	Methanol	92-96	pyruvate dehydrogenase phosphatase catalytic subunit 1	Homo sapiens	215-218
25314333-2	2014	Rapid formation of the catalytically active solvent-coordinated hydride species [(dadpx)PdH(MeOH)](+) (3-MeOH) is evidenced by NMR spectroscopy, and further isolation and X-ray crystal structure analysis of [(dadpx)PdH(PPh3 )](+) (3-PPh3 ).	Methanol	92-96	protein phosphatase 4 catalytic subunit	Homo sapiens	219-223
25314333-2	2014	Rapid formation of the catalytically active solvent-coordinated hydride species [(dadpx)PdH(MeOH)](+) (3-MeOH) is evidenced by NMR spectroscopy, and further isolation and X-ray crystal structure analysis of [(dadpx)PdH(PPh3 )](+) (3-PPh3 ).	Methanol	92-96	protein phosphatase 4 catalytic subunit	Homo sapiens	233-237
25393647-0	2014	Solid state isostructural behavior and quantified limiting substitution kinetics in Schiff-base bidentate ligand complexes fac-[Re(O,N-Bid)(CO)3(MeOH)](n).	Methanol	145-149	BH3 interacting domain death agonist	Homo sapiens	135-138
25241797-5	2014	Treatment of MDA-MB-231 cells with an ethanol extract of C. rotundu rhizomes (EECR) and a methanol extract of C. rotundu rhizomes (MECR), but not a water extract of C. rotundu rhizomes, resulted in potent antiproliferative activity.	Methanol	90-98	mitochondrial trans-2-enoyl-CoA reductase	Homo sapiens	131-135
25278015-0	2014	Bioprocess and downstream optimization of recombinant bovine chymosin B in Pichia (Komagataella) pastoris under methanol-inducible AOXI promoter.	Methanol	112-120	chymosin	Bos taurus	61-69
25278015-3	2014	The effect of biomass level at the beginning of methanol-induction phase on cell growth and chymosin expression was evaluated, determining that a high concentration of cells at the start of such period generated an increase in the production of chymosin.	Methanol	48-56	chymosin	Bos taurus	245-253
25278015-4	2014	The impact of the specific growth rate on chymosin expression was studied throughout the induction stage by methanol exponential feeding fermentations in a lab-scale stirred bioreactor, achieving the highest production of heterologous chymosin with a constant specific growth rate of 0.01h(-1).	Methanol	108-116	chymosin	Bos taurus	42-50
25278015-4	2014	The impact of the specific growth rate on chymosin expression was studied throughout the induction stage by methanol exponential feeding fermentations in a lab-scale stirred bioreactor, achieving the highest production of heterologous chymosin with a constant specific growth rate of 0.01h(-1).	Methanol	108-116	chymosin	Bos taurus	235-243
25285662-2	2014	Ring-opening of the resulting dihydropyranones and subsequent alcoholysis of the CCl3 ketone with an excess of methanol gives a range of diesters in high diastereo- and enantioselectivity (up to 95 : 5 dr and &gt;99% ee).	Methanol	111-119	C-C motif chemokine ligand 3	Homo sapiens	81-85
26080495-4	2014	RESULTS: The IGF-I (60.8 ng/g) in deer antler by solid phase extraction was only existed in 30% methanol aqueous solution which was much higher than that (46.1 ng/g) by ethanol precipitation method.	Methanol	96-104	insulin like growth factor 1	Homo sapiens	13-18
25266135-1	2014	Microscopic interactions of an imidazolium-based ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide (C2mimTFSI), with dimethyl sulfoxide (DMSO), methanol (MeOH), and acetonitrile (AN) have been analyzed by means of Raman, attenuated total reflectance infrared (ATR-IR), (1)H and (13)C NMR spectroscopy techniques.	Methanol	171-179	complement C2	Homo sapiens	127-136
25266135-1	2014	Microscopic interactions of an imidazolium-based ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide (C2mimTFSI), with dimethyl sulfoxide (DMSO), methanol (MeOH), and acetonitrile (AN) have been analyzed by means of Raman, attenuated total reflectance infrared (ATR-IR), (1)H and (13)C NMR spectroscopy techniques.	Methanol	181-185	complement C2	Homo sapiens	127-136
25153643-3	2014	In this work with methanol as the solvent, we investigate the formation of the methoxy analogue of the therapeutic drug Pc 4, (termed Pc 233) upon irradiation.	Methanol	18-26	proprotein convertase subtilisin/kexin type 4	Homo sapiens	120-124
25295856-7	2014	Further analysis in C. elegans showed that the MeOH extract (fraction 3) of tea seed pomace significantly decreased intracellular reactive oxygen species, prolonged C. elegans lifespan, and reduced amyloid-beta (Abeta) toxicity in transgenic C. elegans expressing human Abeta.	Methanol	47-51	amyloid beta precursor protein	Homo sapiens	212-217
25325162-4	2014	Methanol is formed selectively in 87% Faradaic yield in controlled potential electrolyses at 1.3 V vs NHE.	Methanol	0-8	solute carrier family 9 member C1	Homo sapiens	102-105
24845874-3	2014	The result indicated that the compound shows high selectivity for Hg2+ over other metal ions with detectable fluorescent signals in aqueous-methanol media.	Methanol	140-148	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	66-69
25322076-5	2014	Steady-state and time-resolved fluorescence spectroscopies were used to measure the equilibrium, lifetime, and rotational response of coumarin 153 (C153) in neat and MeOH cosolvent modified PIL-Cl.	Methanol	166-170	serpin family A member 2 (gene/pseudogene)	Homo sapiens	190-193
25322076-6	2014	The collective set of data depicts the formation of an increasingly aggregated solvent structure that changes in proportion to the amount of PIL-Cl present in MeOH.	Methanol	159-163	serpin family A member 2 (gene/pseudogene)	Homo sapiens	141-144
25493192-2	2014	An active recombinant methanol-inducible bovine chymosin has been expressed in our laboratory in the yeastKomagataella pastoris, and grape pomace extracts (GRE) were proposed as a convenient C-energy source for the biomass production of the genetically engineered strain.	Methanol	22-30	chymosin	Bos taurus	48-56
25493192-5	2014	Applying a fed-batch strategy with methanol:sorbitol as the enzyme inducers, a chymosin production of 8.53 International Milk Clotting Units (IMCU) per mg protein was obtained in the supernatant.	Methanol	35-43	chymosin	Bos taurus	79-87
25194675-9	2014	Methanol extract strongly inhibited the granuloma tissue formation in rats and the anti-inflammatory potential was mediated through the inhibition of pro-inflammatory cytokines and COX-2 enzyme activities.	Methanol	0-8	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	181-186
25222814-8	2014	A dioxin-responsive luciferase reporter gene assay confirmed that the CYP1A4 inductions were independent of the dissolution solvents used (tetrahydrofuran/n-hexane, n-hexane, or methanol) during photolysis.	Methanol	178-186	cytochrome P450 1A4	Gallus gallus	70-76
25441150-3	2014	The methanol extract of A. arguta (20 mug/mL) stems lowered nitric oxide production in LPS-stimulated Raw 264.7 cells by 40%.	Methanol	4-12	toll-like receptor 4	Mus musculus	87-90
25275568-3	2014	Dissociative adsorption of methanol at different sites on VO2 CeO2(111) is highly exothermic with adsorption energies of 1.8 to 1.9 eV (HSE+D).	Methanol	27-35	hydroxysteroid 17-beta dehydrogenase 6	Homo sapiens	136-139
24745549-5	2014	The expression conditions were optimized, and the highest expression level of LYZL6 occurred when the recombinant strain was induced with 1.5% methanol under pH 4.5 at 24 C for 96 h. When high cell density fermentation of the recombinant P. pastoris was performed using a fed-batch strategy for totally 125 h in a 30 L fermenter, the dry cell weight and the extracellular lysozyme activity were increased to 116.3 g/L and 2340 U/mL, respectively.	Methanol	143-151	lysozyme like 6	Sus scrofa	78-83
25360141-5	2014	In the presence of methanol the kinetics and amplitudes of DAMP/MAMP-induced MAP kinase (MAPK) activity and oxidative burst are altered in tobacco and tomato suspension-cultured cells, in Arabidopsis seedlings and tomato leaf tissue.	Methanol	19-27	mitogen-activated protein kinase kinase 6-like	Nicotiana tabacum	77-87
25360141-5	2014	In the presence of methanol the kinetics and amplitudes of DAMP/MAMP-induced MAP kinase (MAPK) activity and oxidative burst are altered in tobacco and tomato suspension-cultured cells, in Arabidopsis seedlings and tomato leaf tissue.	Methanol	19-27	mitogen-activated protein kinase kinase 6-like	Nicotiana tabacum	89-93
25360141-7	2014	In cell cultures of the grass tall fescue (Festuca arundinacea, Poaceae, Monocots), methanol alone activates MAPKs and increases chitosan-induced MAPK activity, and in the darnel grass Lolium temulentum (Poaceae), it alters wound-induced MAPK signaling.	Methanol	84-92	mitogen-activated protein kinase kinase 6-like	Nicotiana tabacum	109-113
25360141-7	2014	In cell cultures of the grass tall fescue (Festuca arundinacea, Poaceae, Monocots), methanol alone activates MAPKs and increases chitosan-induced MAPK activity, and in the darnel grass Lolium temulentum (Poaceae), it alters wound-induced MAPK signaling.	Methanol	84-92	mitogen-activated protein kinase kinase 6-like	Nicotiana tabacum	146-150
25192004-3	2014	The solvated MeOH or EtOH molecules occupy vacant space, giving contacts with [1-4](2+), and connects to the Hal(-) ion through a hydrogen bridge via the H(1O)O(1S) H atom forming, by means of the Hal(-)   HOR (Hal = Cl, Br) contact, the halide-alcohol cluster.	Methanol	13-17	histidine ammonia-lyase	Homo sapiens	109-112
25192004-3	2014	The solvated MeOH or EtOH molecules occupy vacant space, giving contacts with [1-4](2+), and connects to the Hal(-) ion through a hydrogen bridge via the H(1O)O(1S) H atom forming, by means of the Hal(-)   HOR (Hal = Cl, Br) contact, the halide-alcohol cluster.	Methanol	13-17	histidine ammonia-lyase	Homo sapiens	197-200
25192004-3	2014	The solvated MeOH or EtOH molecules occupy vacant space, giving contacts with [1-4](2+), and connects to the Hal(-) ion through a hydrogen bridge via the H(1O)O(1S) H atom forming, by means of the Hal(-)   HOR (Hal = Cl, Br) contact, the halide-alcohol cluster.	Methanol	13-17	histidine ammonia-lyase	Homo sapiens	197-200
25138353-7	2014	MATERIALS AND METHODS: Sixty nine methanol extracts of TM plants were screened for their ability to induce CYPs by human aryl hydrocarbon receptor- (hAhR-) and human pregnane X receptor- (hPXR-) dependent mechanisms, utilizing a commercially available cell-based luciferase reporter system.	Methanol	34-42	aryl hydrocarbon receptor	Homo sapiens	121-146
25053644-0	2014	Effect of exogenous methanol on glycolate oxidase and photorespiratory intermediates in cotton.	Methanol	20-28	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	32-49
25053644-3	2014	In this study, we investigated the effects of foliar application of MeOH (30%, v/v) on glycolate oxidase (GO) activity and photorespiratory intermediates in cotton leaves in a field experiment.	Methanol	68-72	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	87-104
25053644-3	2014	In this study, we investigated the effects of foliar application of MeOH (30%, v/v) on glycolate oxidase (GO) activity and photorespiratory intermediates in cotton leaves in a field experiment.	Methanol	68-72	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	106-108
25053644-4	2014	MeOH treatment significantly inhibited GO activity (by 30% compared with the controls).	Methanol	0-4	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	39-41
25053644-7	2014	These results thus demonstrated that exogenous MeOH can modulate GO activity and the production of photorespiratory intermediates, and sheds new lights on our current understanding of how exogenous MeOH inhibits photorespiration and enhances the growth and yield of C3 plants such as cotton.	Methanol	47-51	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	65-67
25053644-7	2014	These results thus demonstrated that exogenous MeOH can modulate GO activity and the production of photorespiratory intermediates, and sheds new lights on our current understanding of how exogenous MeOH inhibits photorespiration and enhances the growth and yield of C3 plants such as cotton.	Methanol	198-202	peroxisomal (S)-2-hydroxy-acid oxidase	Gossypium hirsutum	65-67
25138353-7	2014	MATERIALS AND METHODS: Sixty nine methanol extracts of TM plants were screened for their ability to induce CYPs by human aryl hydrocarbon receptor- (hAhR-) and human pregnane X receptor- (hPXR-) dependent mechanisms, utilizing a commercially available cell-based luciferase reporter system.	Methanol	34-42	aryl hydrocarbon receptor	Homo sapiens	149-153
25138353-7	2014	MATERIALS AND METHODS: Sixty nine methanol extracts of TM plants were screened for their ability to induce CYPs by human aryl hydrocarbon receptor- (hAhR-) and human pregnane X receptor- (hPXR-) dependent mechanisms, utilizing a commercially available cell-based luciferase reporter system.	Methanol	34-42	nuclear receptor subfamily 1 group I member 2	Homo sapiens	166-185
25167462-5	2014	Although, the k2 of CS2 insertion reaction ranged from (3.43 +- 0.10) M(-1) s(-1) in methanol to (24.0 +- 0.5) M(-1) s(-1) in N,N-dimethylformamide, which is 1000 times faster than CO2 insertion.	Methanol	85-93	chorionic somatomammotropin hormone 2	Homo sapiens	20-23
24727604-0	2014	Biofuel cell for generating power from methanol substrate using alcohol oxidase bioanode and air-breathed laccase biocathode.	Methanol	39-47	acyl-CoA oxidase 1	Homo sapiens	64-79
24727604-1	2014	We report here an alcohol oxidase (AOx) based third generation bioanode for generating power from methanol substrate in a fuel cell setup using air breathed laccase biocathode.	Methanol	98-106	acyl-CoA oxidase 1	Homo sapiens	18-33
24727604-1	2014	We report here an alcohol oxidase (AOx) based third generation bioanode for generating power from methanol substrate in a fuel cell setup using air breathed laccase biocathode.	Methanol	98-106	acyl-CoA oxidase 1	Homo sapiens	35-38
24117206-0	2014	The alpha-effect in gas-phase SN2 reactions of microsolvated anions: methanol as a solvent.	Methanol	69-77	solute carrier family 38 member 5	Homo sapiens	30-33
25167462-8	2014	1b reacted with CO2 slowly in the methanol with a k2 of (1.46 +- 0.09) x 10(-3) M(-1) s(-1), yielding a formate complex [Ru(eta(1)-OC(H) O)(bpy)2(PPh3)]PF6 (2b).	Methanol	34-42	caveolin 1	Homo sapiens	146-150
25167462-8	2014	1b reacted with CO2 slowly in the methanol with a k2 of (1.46 +- 0.09) x 10(-3) M(-1) s(-1), yielding a formate complex [Ru(eta(1)-OC(H) O)(bpy)2(PPh3)]PF6 (2b).	Methanol	34-42	sperm associated antigen 17	Homo sapiens	152-155
25186468-12	2014	CONCLUSIONS: The production of recombinant hA(2a)R, GFP and hCGRP-RCP-GFP can be detected in bioreactor cultivations prior to methanol induction, while this is not the case for shake-flask cultivations of GFP, HRP, hCD81, hCD82 and human claudin-1.	Methanol	126-134	CGRP receptor component	Homo sapiens	60-69
25194368-6	2014	of the C-H stretching bands based on the B3LYP/ANO1 harmonic frequencies, showing that nu3, nu9, and nu2 C-H stretching modes of the proton-accepting (PA) and proton-donating (PD) methanol monomers experience only small splittings upon the cluster formation.	Methanol	180-188	anoctamin 1	Homo sapiens	47-51
25924408-2	2014	The dechlorination of CCl4 to dichloromethane (CH2Cl2) and chloroform (CHCl3) with a molar ratio of 3:2 was catalyzed by carbon-supported silver (Ag/C) catalyst in methanol solution.	Methanol	164-172	C-C motif chemokine ligand 4	Homo sapiens	22-26
25123712-3	2014	Optimizations of the structures of dioxane-methanol complexes were carried out considering any spatial orientation of a methanol molecule around a chair/boat/twisted-boat conformation of dioxane.	Methanol	43-51	ataxin 1 like	Homo sapiens	153-157
25177362-1	2014	BACKGROUND: Electro-oxidation of methanol in acidic solution was investigated on a Pt/SnO2 based electrocatalyst obtained by the sol-gel method.	Methanol	33-41	strawberry notch homolog 2	Homo sapiens	86-89
25123712-3	2014	Optimizations of the structures of dioxane-methanol complexes were carried out considering any spatial orientation of a methanol molecule around a chair/boat/twisted-boat conformation of dioxane.	Methanol	43-51	ataxin 1 like	Homo sapiens	166-170
25221549-6	2014	Notably, deep sequencing also revealed that some methylotrophs dramatically increased after MEP application, strongly suggesting that these bacteria play a role in the consumption and removal of methanol, a harmful derivative from MEP-degradation, for better growth of MEP-degrading bacteria.	Methanol	195-203	neurolysin	Homo sapiens	92-95
25221549-6	2014	Notably, deep sequencing also revealed that some methylotrophs dramatically increased after MEP application, strongly suggesting that these bacteria play a role in the consumption and removal of methanol, a harmful derivative from MEP-degradation, for better growth of MEP-degrading bacteria.	Methanol	195-203	neurolysin	Homo sapiens	231-234
25221549-6	2014	Notably, deep sequencing also revealed that some methylotrophs dramatically increased after MEP application, strongly suggesting that these bacteria play a role in the consumption and removal of methanol, a harmful derivative from MEP-degradation, for better growth of MEP-degrading bacteria.	Methanol	195-203	neurolysin	Homo sapiens	231-234
25088995-1	2014	The zinc finger transcription factors Mxr1p and Rop are key regulators of methanol metabolism in the methylotrophic yeast, Pichia pastoris, while Trm1p and Trm2p regulate methanol metabolism in Candida boidinii.	Methanol	74-82	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	38-43
25135691-5	2014	METHODS: The CGN was successively extracted with petroleum ether (PE), acetone and methanol.	Methanol	83-91	cingulin	Homo sapiens	13-16
25088995-1	2014	The zinc finger transcription factors Mxr1p and Rop are key regulators of methanol metabolism in the methylotrophic yeast, Pichia pastoris, while Trm1p and Trm2p regulate methanol metabolism in Candida boidinii.	Methanol	171-179	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	38-43
24910406-0	2014	Korean Scutellaria baicalensis Georgi methanol extracts inhibits metastasis via the Forkhead Box M1 activity in hepatocellular carcinoma cells.	Methanol	38-46	forkhead box M1	Homo sapiens	84-99
25093354-6	2014	PXRD further suggests that the NCL monohydrate, HA, is isostructural with the NCL MeOH solvate.	Methanol	82-86	nucleolin	Homo sapiens	31-34
25106881-4	2014	In our previous report, a methanol extract of its aerial parts was shown to exhibit estrogenic and aryl hydrocarbon receptor agonistic activities in vitro and to prevent menopausal symptoms in ovariectomized Wistar rats.	Methanol	26-34	aryl hydrocarbon receptor	Rattus norvegicus	99-124
25093354-6	2014	PXRD further suggests that the NCL monohydrate, HA, is isostructural with the NCL MeOH solvate.	Methanol	82-86	nucleolin	Homo sapiens	78-81
25093354-3	2014	The essentially planar NCL host molecules interact via pi-stacking and pack in a herringbone-type arrangement, giving rise to channels along the crystallographic a axis in which the methanol guest molecules are located.	Methanol	182-190	nucleolin	Homo sapiens	23-26
24912992-1	2014	The objective of this work was to investigate the effects of the methanol extracts of Gentiana cruciata L. aerial parts (GCA) and roots (GCR) against carbon tetrachloride-induced liver injury in rats.	Methanol	65-73	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	137-140
25093354-5	2014	Laboratory powder X-ray diffraction (PXRD) measurements reveal that the initially phase-pure NCL MeOH solvate readily transforms into NCL monohydrate within hours under ambient conditions.	Methanol	97-101	nucleolin	Homo sapiens	93-96
25093354-5	2014	Laboratory powder X-ray diffraction (PXRD) measurements reveal that the initially phase-pure NCL MeOH solvate readily transforms into NCL monohydrate within hours under ambient conditions.	Methanol	97-101	nucleolin	Homo sapiens	134-137
25084904-3	2014	It is expected that in going from 300 K to 0.4 K (the temperature of helium nanodroplets) the population distribution of methanol will mainly collapse into two states; the JK = 00 state for the A1 nuclear spin symmetry species (with ICH3 = 3/2), and the JK = 1-1 state for the E species (ICH3 = 1/2).	Methanol	121-129	caspase 5	Homo sapiens	233-237
24533630-3	2014	In this study, we report the effect of commonly used organic solvents such as dimethyl sulfoxide (DMSO), acetonitrile (ACN), methanol and ethanol on AOX activity in human, rat and mouse liver S9 fractions using vanillin, phthalazine and methotrexate as probe substrates.	Methanol	125-133	aldehyde oxidase 1	Homo sapiens	149-152
24220877-5	2014	Expression of dehydrogenase (formaldehyde dehydrogenase (FDH)) in the formaldehyde (10.40) and methanol (10.60) groups increased significantly compared with the control (1), while it was similar to the control in formic acid (0.90) and acetaldehyde (1.10) groups.	Methanol	95-103	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	29-55
24220877-5	2014	Expression of dehydrogenase (formaldehyde dehydrogenase (FDH)) in the formaldehyde (10.40) and methanol (10.60) groups increased significantly compared with the control (1), while it was similar to the control in formic acid (0.90) and acetaldehyde (1.10) groups.	Methanol	95-103	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	57-60
25434113-12	2014	And a baseline separation of polar compounds such as amines and phenols on ESP was easily achieved by using common and cheap methanol-water mobile phases without buffer salts.	Methanol	125-133	protein tyrosine phosphatase receptor type V, pseudogene	Homo sapiens	75-78
25429469-5	2014	RESULTS: The crude hexane and methanol extracts of V divaricata were able to significantly retard the growth of the MCF-7 (breast), HL-60 (leukaemia) and the PC-3 (prostate) cancer cell lines.	Methanol	30-38	BTG anti-proliferation factor 2	Homo sapiens	158-162
25429469-6	2014	The crude methanol extract of the stem was the strongest, exhibiting anti-proliferation activity with IC50 values of 10.14, 12.63 and 9.894 microg/ml for the HL-60, MCF-7 and PC-3 cancer cell lines, respectively, with the most potent toward prostate cancer.	Methanol	10-18	BTG anti-proliferation factor 2	Homo sapiens	175-179
25084904-3	2014	It is expected that in going from 300 K to 0.4 K (the temperature of helium nanodroplets) the population distribution of methanol will mainly collapse into two states; the JK = 00 state for the A1 nuclear spin symmetry species (with ICH3 = 3/2), and the JK = 1-1 state for the E species (ICH3 = 1/2).	Methanol	121-129	caspase 5	Homo sapiens	288-292
24747731-3	2014	10-Formyltetrahydrofolate dehydrogenase converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2, the only pathway responsible for formate oxidation in methanol intoxication.	Methanol	158-166	aldehyde dehydrogenase 1 family, member L1	Danio rerio	0-39
24968114-0	2014	In situ crystallization of ionic liquid [Emim][PF6] from methanol solution under high pressure.	Methanol	57-65	sperm associated antigen 17	Homo sapiens	47-50
24968114-1	2014	The solubility of 1-ethyl-3-methylimidazolium hexafluorophosphate ([Emim][PF6]) in methanol under high pressure is newly measured quantitatively according to the correlation between the ratios of Raman intensity and the concentrations.	Methanol	83-91	sperm associated antigen 17	Homo sapiens	74-77
24968114-2	2014	In situ crystallization and cation conformation of [Emim][PF6] from methanol solution under high pressure have been investigated by using Raman spectroscopy in detail.	Methanol	68-76	sperm associated antigen 17	Homo sapiens	58-61
25006999-5	2014	Methanol gas sorption of the different MIL materials correlates with the BET surface area and pore volume but not with the diacetalization activity.	Methanol	0-8	delta/notch like EGF repeat containing	Homo sapiens	73-76
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	222-227
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	sorting nexin 27	Homo sapiens	232-237
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	membrane metalloendopeptidase	Homo sapiens	283-286
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	sortilin related receptor 1	Homo sapiens	288-293
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	DNA damage inducible transcript 4	Homo sapiens	295-300
25033451-7	2014	A qRT-PCR analysis of volunteer WBCs after pectin and red wine intake confirmed the complicated relationship between the plasma MeOH content and the mRNA accumulation of both genes that were previously identified, namely, GAPDH and SNX27, and genes revealed in this study, including MME, SORL1, DDIT4, HBA and HBB.	Methanol	128-132	hemoglobin subunit beta	Homo sapiens	310-313
24888820-4	2014	By application of ruthenium pincer complexes, a simultaneous methanol dehydrogenation and bicarbonate hydrogenation reaction proceeds, which provides a green synthesis of formate salts with excellent TON (&gt;18,000), TOF (&gt;1300 h(-1)), and yield (&gt;90%).	Methanol	61-69	FEZ family zinc finger 2	Homo sapiens	218-221
24757978-4	2014	The crystalline nucleus was formed scaterringly on the mica surface at 10% methylalcohol.	Methanol	75-88	MHC class I polypeptide-related sequence A	Homo sapiens	55-59
25053546-2	2014	AIM: To study the hepatoprotective effect of methanol extract of Gentiana veitchiorum (MGV) against CCl4-induced oxidative stress and liver injury in mice.	Methanol	45-53	chemokine (C-C motif) ligand 4	Mus musculus	100-104
24789471-9	2014	Our results demonstrate that methanol extracts of S. koreana leaves promote the proliferation and migration of skin fibroblasts and possess effective wound healing activity through the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways.	Methanol	29-37	midkine	Mus musculus	203-206
24789471-9	2014	Our results demonstrate that methanol extracts of S. koreana leaves promote the proliferation and migration of skin fibroblasts and possess effective wound healing activity through the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways.	Methanol	29-37	mitogen-activated protein kinase 3	Mus musculus	207-213
24923510-2	2014	The photoconversion under UV irradiation of both pesticides into strongly fluorescent photoproducts was performed in several media (methanol, ethanol, acetonitrile, pH4 aqueous solution and pH4 water-methanol (30:70, v/v) mixture).	Methanol	200-208	prolyl 4-hydroxylase, transmembrane	Homo sapiens	190-193
24840643-2	2014	Here we report a combined high-pressure diffraction and computational study of the structural response to methanol uptake at high pressure on a scandium terephthalate MOF (Sc2BDC3, BDC = 1,4-benzenedicarboxylate) and its nitro-functionalized derivative (Sc2(NO2-BDC)3) and compare it to direct compression behavior in a nonpenetrative hydrostatic fluid, Fluorinert-77.	Methanol	106-114	lysine acetyltransferase 8	Homo sapiens	167-170
25001225-3	2014	By high-performance liquid chromatography (HPLC), we found that A2E and ATR-dimer were both altered by tetrahydrofuran (THF) and chloroform, but were stable in dimethyl sulfoxide (DMSO) or methanol (MeOH).	Methanol	189-197	ATR serine/threonine kinase	Homo sapiens	72-75
25001225-3	2014	By high-performance liquid chromatography (HPLC), we found that A2E and ATR-dimer were both altered by tetrahydrofuran (THF) and chloroform, but were stable in dimethyl sulfoxide (DMSO) or methanol (MeOH).	Methanol	199-203	ATR serine/threonine kinase	Homo sapiens	72-75
25001939-3	2014	A large-scale expression of recombinant Csa2 protein (rCsa2) was optimized using methanol, and the protein was purified in P. pastoris expression system.	Methanol	81-89	IK cytokine	Rattus norvegicus	40-44
25001939-3	2014	A large-scale expression of recombinant Csa2 protein (rCsa2) was optimized using methanol, and the protein was purified in P. pastoris expression system.	Methanol	81-89	IK cytokine	Rattus norvegicus	54-59
25161531-1	2014	The title compound, [Ru(CO3)(eta(6)-C6H6){(C6H11)2P(CH2C10H7)}] 3CHCl3, was synthesized by carbonation of [RuCl2(eta(6)-C6H6){(C6H11)2P(CH2C10H7)}] with NaHCO3 in methanol at room temperature.	Methanol	163-171	endothelin receptor type A	Homo sapiens	29-32
24840643-2	2014	Here we report a combined high-pressure diffraction and computational study of the structural response to methanol uptake at high pressure on a scandium terephthalate MOF (Sc2BDC3, BDC = 1,4-benzenedicarboxylate) and its nitro-functionalized derivative (Sc2(NO2-BDC)3) and compare it to direct compression behavior in a nonpenetrative hydrostatic fluid, Fluorinert-77.	Methanol	106-114	trans-2,3-enoyl-CoA reductase	Homo sapiens	172-175
24799257-2	2014	In this study, screening of 99 crude drugs for retinoic acid receptor (RAR) ligands by luciferase reporter assay demonstrated that the methanol extract of Aralia cordata Rhizoma most effectively activates the transcriptional activity of RARalpha.	Methanol	135-143	retinoic acid receptor alpha	Homo sapiens	71-74
24806731-3	2014	The addition of HTFA to [((t)bpy)2Rh(OMe)2][OTf] leads to the formation of [((t)bpy)2Rh(OMe)(MeOH)][OTf][TFA], which exists in equilibrium with [((t)bpy)2Rh(OMe)(TFA)][OTf].	Methanol	93-97	coagulation factor III, tissue factor	Homo sapiens	17-20
24115758-7	2014	The polar organic mode containing small amounts of methanol in acetonitrile was the most useful solvent system for the LARIHC CF6-P CSP.	Methanol	51-59	ATP synthase peripheral stalk subunit F6	Homo sapiens	126-129
24773055-3	2014	The picosecond experiments show the importance of the interactions of C30 with the medium, as well as the intramolecular events in the excited-state relaxation as evidenced by the increase in the global emission lifetime from ~0.5 ns in MeOH/H2O mixtures to 2.5 ns in THF, and to 1-3 ns when the dye is trapped within CDs and HSA cavities.	Methanol	237-241	albumin	Homo sapiens	326-329
24773055-5	2014	The rotational time decays clearly show the robustness of the formed complexes with CDs and HSA protein: ~170 ps in MeOH/H2O solvent mixtures, ~850 ps due to 1:1 and 1:2 beta-CD complexes, and 28 ns for HSA complexes.	Methanol	116-120	albumin	Homo sapiens	92-95
24784975-5	2014	Data from the chemical portion of non-PPO darkening is consistent with the presence of a PPO-like enzyme that oxidizes tyrosine, has a pH maximum of 8.1, and is inhibited by 50% methanol or ethanol but in the noodle is insensitive to PPO inhibitors such as tropolone.	Methanol	178-186	polyphenol oxidase I, chloroplastic	Triticum aestivum	38-41
24784975-5	2014	Data from the chemical portion of non-PPO darkening is consistent with the presence of a PPO-like enzyme that oxidizes tyrosine, has a pH maximum of 8.1, and is inhibited by 50% methanol or ethanol but in the noodle is insensitive to PPO inhibitors such as tropolone.	Methanol	178-186	polyphenol oxidase I, chloroplastic	Triticum aestivum	89-92
24784975-5	2014	Data from the chemical portion of non-PPO darkening is consistent with the presence of a PPO-like enzyme that oxidizes tyrosine, has a pH maximum of 8.1, and is inhibited by 50% methanol or ethanol but in the noodle is insensitive to PPO inhibitors such as tropolone.	Methanol	178-186	polyphenol oxidase I, chloroplastic	Triticum aestivum	89-92
24806731-3	2014	The addition of HTFA to [((t)bpy)2Rh(OMe)2][OTf] leads to the formation of [((t)bpy)2Rh(OMe)(MeOH)][OTf][TFA], which exists in equilibrium with [((t)bpy)2Rh(OMe)(TFA)][OTf].	Methanol	93-97	coagulation factor III, tissue factor	Homo sapiens	105-108
24806731-6	2014	Combined experimental and computational studies have led to a proposed mechanism for hydrogen activation by [((t)bpy)2Rh(OMe)(MeOH)][OTf][TFA] that involves dissociation of MeOH, coordination of hydrogen, and 1,2-addition of hydrogen across the Rh-OMe bond.	Methanol	126-130	coagulation factor III, tissue factor	Homo sapiens	138-141
24806731-6	2014	Combined experimental and computational studies have led to a proposed mechanism for hydrogen activation by [((t)bpy)2Rh(OMe)(MeOH)][OTf][TFA] that involves dissociation of MeOH, coordination of hydrogen, and 1,2-addition of hydrogen across the Rh-OMe bond.	Methanol	173-177	coagulation factor III, tissue factor	Homo sapiens	138-141
24700693-3	2014	Surprisingly, the experiments presented here suggest that the spin ground state of diphenylcarbene 1 switches from triplet to singlet if the carbene is allowed to interact with methanol.	Methanol	177-185	spindlin 1	Homo sapiens	62-66
24647792-1	2014	Ruthenium(II) PNN complexes depolymerize many polyesters into diols and polycarbonates into glycols plus methanol via hydrogenation.	Methanol	105-113	pinin, desmosome associated protein	Homo sapiens	14-17
24419796-8	2014	Our data demonstrates the biotechnological applicability of the thioesterase YciA and the possibility of EMCP dicarboxylic acid production from methanol using M. extorquens AM1.	Methanol	144-152	MEXAM1_RS06460	Methylobacterium extorquens AM1	64-76
24690308-3	2014	As a result, two previously unobserved monoferric forms of protein have been separated and identified, moreover, the loss of ferric ions from transferrin during electrophoretic separation has been considerably reduced by methanol, and the method selectivity has been yet increased resulting in a total separation of proteins exerting only subtle or none difference in mass-to-charge ratio.	Methanol	221-229	transferrin	Homo sapiens	142-153
24596056-2	2014	Pyrene-substituted PDI were the most efficient singlet oxygen generator among the investigated photosensitizers with a quantum yield of Phi Delta = 0.93 in toluene/methanol.	Methanol	164-172	peptidyl arginine deiminase 1	Homo sapiens	19-22
24360441-3	2014	Thereafter, the cephalosporins-absorbed C18-Fe3O4@mSiO2 microspheres were rapidly isolated by placing a magnet, and followed by liquid chromatography-tandem mass spectrometry analysis after eluted by methanol.	Methanol	200-208	Bardet-Biedl syndrome 9	Homo sapiens	40-43
24689807-6	2014	The propensity for methanol"s self-association in the solvents studied increases in the order: CH2Cl2 ~ CHCl3 &lt; C6H6 &lt; CCl4.	Methanol	19-27	C-C motif chemokine ligand 4	Homo sapiens	125-129
24707804-5	2014	For the prototypical alcohol, methanol, reducing the strength of the proton donor or acceptor leads to a smaller change in the BDE, and a smooth variation of C-H bond strength with the extent of protonation or deprotonation is observed.	Methanol	30-38	homeobox D13	Homo sapiens	127-130
24742159-2	2014	Electrophilic aromatic aldehydes were smoothly converted into delocalized 2-azaallylanions via condensation with 2,2-diphenylglycine in methanol and subsequent decarboxylation in THF and underwent further reaction with N-Ts imines to give a variety of 1,2-diamine derivatives in good yields with high syn/anti diastereoselectivity.	Methanol	136-144	synemin	Homo sapiens	301-304
24611879-5	2014	Guided by the X-ray cocrystal structure of compound 1 bound to hGKRP, we identified several potent GK-GKRP disruptors bearing a diverse set of functionalities in the aryl carbinol region.	Methanol	171-179	glucokinase regulatory protein	Mus musculus	64-68
24579759-19	2014	When we react eta-alumina with methanol, the catalyst forms a chemisorbed methoxy species.	Methanol	31-39	endothelin receptor type A	Homo sapiens	14-17
24189976-5	2014	At present, the standard treatment for Fabry disease is enzyme replacement therapy, and in order to overcome the problems involved with this, a method of producing recombinant human alpha-Gal A using methanol-assimilating yeast, and chemical or medicinal chaperone treatment are of current interest.	Methanol	200-208	galactosidase alpha	Homo sapiens	182-193
24708543-2	2014	The aim of the present study was to determine the hepatoprotective effect of methanol extracts of D. linearis (MEDL) against carbon tetrachloride (CCl4)-induced acute liver injury in rats.	Methanol	77-85	C-C motif chemokine ligand 4	Rattus norvegicus	147-151
24037733-0	2014	Apoptotic effect of methanol extract of Picrasma quassioides by regulating specificity protein 1 in human cervical cancer cells.	Methanol	20-28	Sp1 transcription factor	Homo sapiens	75-96
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	nitric oxide synthase 2, inducible	Mus musculus	67-88
25237368-0	2014	Effect of boswellia thurifera gum methanol extract on cytotoxicity and p53 gene expression in human breast cancer cell line.	Methanol	34-42	tumor protein p53	Homo sapiens	71-74
25237368-2	2014	The aim of this study was to evaluate the effect of the gum methanol extract of Boswellia thurifera on the viability and P53 gene expression of cultured breast cancer cells.	Methanol	60-68	tumor protein p53	Homo sapiens	121-124
25237368-9	2014	This inductive effect in cells was higher after 12 h treatment than it was after 6 h. The results of the current study show that gum methanol extract of Boswellia thurifera has probably anti-cancer effects and could induce P53 gene transcription and toxicity in the cultured breast cancer cell line.	Methanol	133-141	tumor protein p53	Homo sapiens	223-226
25237368-10	2014	The increase of P53 gene specific mRNA may be a mechanism of gum methanol extract induced cytotoxicity.	Methanol	65-73	tumor protein p53	Homo sapiens	16-19
25237338-4	2014	The chromatographic separation was achieved on a C18 column by using 60:40 methanol:water as mobile phase under isocratic conditions at a flow rate of 0.75 mL/min with UV detection at 280 nm in HPLC method.	Methanol	75-83	Bardet-Biedl syndrome 9	Homo sapiens	49-52
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	nitric oxide synthase 2, inducible	Mus musculus	90-94
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	prostaglandin-endoperoxide synthase 2	Mus musculus	100-116
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	prostaglandin-endoperoxide synthase 2	Mus musculus	118-123
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	interleukin 1 beta	Mus musculus	255-272
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	interleukin 1 beta	Mus musculus	274-282
24534870-4	2014	A non-cytotoxic methanol extract of AT inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels of nitric oxide (NO) and prostaglandin E2 (PGE2) and of two proteins regulated by these, interleukin-1beta (IL-1beta) and IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells.	Methanol	16-24	interleukin 6	Mus musculus	288-292
24534870-7	2014	Our results indicated that a methanol extract of AT downregulates the inflammatory response by blocking phosphorylation of MEK and ERK and activation of NF-kappaB.	Methanol	29-37	midkine	Mus musculus	123-126
24534870-7	2014	Our results indicated that a methanol extract of AT downregulates the inflammatory response by blocking phosphorylation of MEK and ERK and activation of NF-kappaB.	Methanol	29-37	mitogen-activated protein kinase 1	Mus musculus	131-134
24296456-2	2014	The conditions of producing 15-HETE from arachidonic acid by using soybean lipoxygenase were optimal at pH 8.5 and 20 C with 9 g/l arachidonic acid, 54.4 U/ml soybean lipoxygenase, and 4% methanol.	Methanol	188-196	linoleate 9S-lipoxygenase-4	Glycine max	75-87
24820272-7	2014	The effect of Abeta and PP on the hippocampus cells was observed by HE and Congo red staining of methanol.	Methanol	97-105	amyloid beta precursor protein	Rattus norvegicus	14-19
24457598-2	2014	When the components are combined in right proportions (metal : ligand : NEt3 : NaN3 = 2 : 1 : 3 : 2) in MeOH, twelve Cu(2+) ions assemble in a cuboctahedral geometry, containing six square and eight triangular faces around a considerable void space.	Methanol	104-108	tetraspanin 2	Homo sapiens	72-76
24672536-3	2014	The mechanical damage that often precedes the penetration of the leaf by a pathogen promotes the activation of PME, which in turn leads to the emission of methanol (MeOH), an abundant volatile organic compound, which is quickly perceived by the intact leaves of the damaged plant, and the neighboring plants.	Methanol	155-163	cystatin B	Homo sapiens	111-114
24672536-3	2014	The mechanical damage that often precedes the penetration of the leaf by a pathogen promotes the activation of PME, which in turn leads to the emission of methanol (MeOH), an abundant volatile organic compound, which is quickly perceived by the intact leaves of the damaged plant, and the neighboring plants.	Methanol	165-169	cystatin B	Homo sapiens	111-114
24057655-1	2014	A series of Schiff bases (L 1 , L 2 and L 3) were prepared by refluxing aromatic aldehydes with N-Aminopyrimidine derivatives in methanol and ethanol.	Methanol	129-137	L1 cell adhesion molecule	Homo sapiens	26-43
25895337-7	2014	And the highest catalytic rate 4.29 microM x min-1 was obtained when the volume ratio of PBs: methanol was 5 : 5.	Methanol	94-102	CD59 molecule (CD59 blood group)	Homo sapiens	45-50
23715855-0	2014	Promising properties of a formate dehydrogenase from a methanol-assimilating yeast Ogataea parapolymorpha DL-1 in His-tagged form.	Methanol	55-63	HPODL_03145	Ogataea parapolymorpha DL-1	26-47
24533148-4	2014	As a result, the methanol extracts of Myoga flower buds, which are traditional Japanese foods, and labdane-type diterpene galanal derived from Myoga flowers significantly suppressed IDO1 activity.	Methanol	17-25	indoleamine 2,3-dioxygenase 1	Homo sapiens	182-186
24253448-4	2014	Following 96 h of methanol induction, Tricine-SDS-PAGE Coomassie staining, western blot analysis and N-terminal protein sequencing revealed that the level of recombinant hIFN-gamma (rhIFN-gamma) secreted by the native secretion signal was barely detectable, while the alpha signal peptide secreted ~300 mg/l.	Methanol	18-26	interferon gamma	Homo sapiens	170-193
24794725-0	2014	Pectin methylesterase-generated methanol may be involved in tobacco leaf growth.	Methanol	32-40	pectinesterase-like	Nicotiana tabacum	0-21
24794725-2	2014	After assessing the role of metabolite signaling in gene regulation in Nicotiana tabacum sink and source leaves, we observed increased pectin methylesterase (PME)-mediated methanol generation in immature leaves.	Methanol	172-180	pectinesterase-like	Nicotiana tabacum	135-156
24794725-2	2014	After assessing the role of metabolite signaling in gene regulation in Nicotiana tabacum sink and source leaves, we observed increased pectin methylesterase (PME)-mediated methanol generation in immature leaves.	Methanol	172-180	pectinesterase-like	Nicotiana tabacum	158-161
24269723-5	2014	For compounds being formally positive (PIF value above 5) the lowest reported molar extinction coefficient (MEC) was 1700 L mol-1 cm-1 in methanol.	Methanol	138-146	PIF1 5'-to-3' DNA helicase	Homo sapiens	39-42
24270523-0	2014	Extracellular signal-regulated kinase inhibition is required for methanol extract of Smilax china L.-induced apoptosis through death receptor 5 in human oral mucoepidermoid carcinoma cells.	Methanol	65-73	mitogen-activated protein kinase 1	Homo sapiens	0-37
24270523-0	2014	Extracellular signal-regulated kinase inhibition is required for methanol extract of Smilax china L.-induced apoptosis through death receptor 5 in human oral mucoepidermoid carcinoma cells.	Methanol	65-73	TNF receptor superfamily member 10b	Homo sapiens	127-143
24354363-3	2014	Equilibrium unfolding of differently charged cytochrome c molecules in water-methanol binary mixtures, where the alcohol acts as the cosolvent denaturant, was used to quantify the preferential exclusion of water during the unfolding transition.	Methanol	77-85	cytochrome c, somatic	Homo sapiens	45-57
24513702-7	2014	CORT from the interior of the hair shaft is extracted into methanol, the methanol is evaporated, and the extract is reconstituted in assay buffer.	Methanol	59-67	cortistatin	Homo sapiens	0-4
24513702-7	2014	CORT from the interior of the hair shaft is extracted into methanol, the methanol is evaporated, and the extract is reconstituted in assay buffer.	Methanol	73-81	cortistatin	Homo sapiens	0-4
24448514-3	2014	In particular, the ternary Au@Ag2S-Pt nanocomposites display superior methanol oxidation reaction (MOR) selectivity due to the electronic coupling effect among different domains of the nanocomposites, while the cage-bell structured Pt-Ru nanoparticles exhibit excellent methanol tolerance for oxygen reduction reaction (ORR) at the cathode because of the differential diffusion of methanol and oxygen in the porous Ru shell of the cage-bell nanoparticles.	Methanol	270-278	angiotensin II receptor type 1	Homo sapiens	30-34
24448514-3	2014	In particular, the ternary Au@Ag2S-Pt nanocomposites display superior methanol oxidation reaction (MOR) selectivity due to the electronic coupling effect among different domains of the nanocomposites, while the cage-bell structured Pt-Ru nanoparticles exhibit excellent methanol tolerance for oxygen reduction reaction (ORR) at the cathode because of the differential diffusion of methanol and oxygen in the porous Ru shell of the cage-bell nanoparticles.	Methanol	70-78	angiotensin II receptor type 1	Homo sapiens	30-34
24415829-2	2014	It was found that the introduction of methanol as co-solvent (35 wt%) to the medium greatly decreases the amount of water-soluble polyelectrolyte in the cases NaAA and Na2ita while it does not make difference for NaSS and NaAmps.	Methanol	38-46	N-acylethanolamine acid amidase	Homo sapiens	159-163
24448514-3	2014	In particular, the ternary Au@Ag2S-Pt nanocomposites display superior methanol oxidation reaction (MOR) selectivity due to the electronic coupling effect among different domains of the nanocomposites, while the cage-bell structured Pt-Ru nanoparticles exhibit excellent methanol tolerance for oxygen reduction reaction (ORR) at the cathode because of the differential diffusion of methanol and oxygen in the porous Ru shell of the cage-bell nanoparticles.	Methanol	270-278	angiotensin II receptor type 1	Homo sapiens	30-34
24290170-4	2014	The optimum chromatographic conditions are C18 column eluted with methanol:water:acetic acid (90:9.9:0.1, v/v/v); column temperature, 26 C; flow rate, 1.0mL/min.	Methanol	66-74	Bardet-Biedl syndrome 9	Homo sapiens	43-46
24405865-12	2014	Increased expression of tkt(P), but not of tkt(C) during growth with methanol [J Bacteriol 188:3063-3072, 2006] argues for TKT(P) being the major TKT relevant in the RuMP pathway.	Methanol	69-77	tkt	Bacillus methanolicus MGA3	24-27
24405865-12	2014	Increased expression of tkt(P), but not of tkt(C) during growth with methanol [J Bacteriol 188:3063-3072, 2006] argues for TKT(P) being the major TKT relevant in the RuMP pathway.	Methanol	69-77	tkt	Bacillus methanolicus MGA3	123-126
26276186-7	2014	Finally, the ESIPT process in 2-BFP is inhibited in protic solvents (MeOH) or by the formation of metal-chelate complexes, providing insights for further developments and applications of ESIPT molecules.	Methanol	69-73	ring finger protein 112	Homo sapiens	32-35
24875271-1	2014	The dissolution of the antihypertensive AT1 antagonist olmesartan in methanol generates in situ a new highly bioactive methyl ether analogue via SN1 mechanism involving an intramolecular proton transfer from carboxyl to hydroxyl group.	Methanol	69-77	angiotensin II receptor type 1	Homo sapiens	40-43
24875271-1	2014	The dissolution of the antihypertensive AT1 antagonist olmesartan in methanol generates in situ a new highly bioactive methyl ether analogue via SN1 mechanism involving an intramolecular proton transfer from carboxyl to hydroxyl group.	Methanol	69-77	solute carrier family 38 member 3	Homo sapiens	145-148
24741615-1	2014	Flow cytometric analysis of p38 mitogen-activated protein kinase (p38 MAPK) signaling cascade is optimally achieved by methanol permeabilization protocols.	Methanol	119-127	mitogen-activated protein kinase 14	Homo sapiens	28-64
24345236-7	2014	The majority of the IL-6 release and cytotoxicity was induced upon exposure to the most polar (methanol) SPE fraction of extracts from both samples.	Methanol	95-103	interleukin 6	Homo sapiens	20-24
24741615-1	2014	Flow cytometric analysis of p38 mitogen-activated protein kinase (p38 MAPK) signaling cascade is optimally achieved by methanol permeabilization protocols.	Methanol	119-127	mitogen-activated protein kinase 14	Homo sapiens	66-74
24287397-9	2013	Furthermore, the methanol-treated SELP fibre mats showed no cytotoxicity and were able to support adhesion and proliferation of normal human skin fibroblasts.	Methanol	17-25	selectin P	Homo sapiens	34-38
24169732-3	2013	The study revealed that all the three hybrid materials are active for both methanol oxidation (MOR) and oxygen reduction (ORR) reactions in 1 M KOH.	Methanol	75-83	opioid receptor mu 1	Homo sapiens	95-98
24144811-0	2013	Molecular mechanism of deactivation of C. antarctica lipase B by methanol.	Methanol	65-73	PAN0_003d1715	Moesziomyces antarcticus	53-59
24014151-4	2013	The APPI HDX spectra obtained with contact times between the analyte solution and methanol-OD (CH3OD) of &lt; 0.5 s or 1 h showed the same pattern of H/D exchange.	Methanol	82-90	amyloid beta precursor protein	Homo sapiens	4-8
24144811-1	2013	The catalytic activity of Candida antarctica lipase B upon alcoholysis of a constant concentration of 15.2% vinyl acetate (vol/vol) and varying concentrations of methanol (0.7-60%) in toluene was determined experimentally by measuring the initial reaction velocity.	Methanol	162-170	PAN0_003d1715	Moesziomyces antarcticus	45-51
24144811-2	2013	The molecular mechanism of the deactivation of the enzyme by methanol was investigated by fitting the experimental data to a kinetic model and by molecular dynamics simulations of C. antarctica lipase B in toluene-methanol-water mixtures.	Methanol	61-69	PAN0_003d1715	Moesziomyces antarcticus	194-200
24144811-7	2013	Two equilibrium constants of methanol (KM,MeOH=0.05 and Ki,MeOH=0.23) were derived by modeling methanol binding to the substrate binding site of the lipase in molecular dynamics simulations of protein-solvent systems at atomic resolution.	Methanol	29-37	PAN0_003d1715	Moesziomyces antarcticus	149-155
24144811-7	2013	Two equilibrium constants of methanol (KM,MeOH=0.05 and Ki,MeOH=0.23) were derived by modeling methanol binding to the substrate binding site of the lipase in molecular dynamics simulations of protein-solvent systems at atomic resolution.	Methanol	42-46	PAN0_003d1715	Moesziomyces antarcticus	149-155
24144811-7	2013	Two equilibrium constants of methanol (KM,MeOH=0.05 and Ki,MeOH=0.23) were derived by modeling methanol binding to the substrate binding site of the lipase in molecular dynamics simulations of protein-solvent systems at atomic resolution.	Methanol	59-63	PAN0_003d1715	Moesziomyces antarcticus	149-155
24144811-7	2013	Two equilibrium constants of methanol (KM,MeOH=0.05 and Ki,MeOH=0.23) were derived by modeling methanol binding to the substrate binding site of the lipase in molecular dynamics simulations of protein-solvent systems at atomic resolution.	Methanol	95-103	PAN0_003d1715	Moesziomyces antarcticus	149-155
24144811-8	2013	Thus, the sharp maximum of catalytic activity of C. antarctica lipase B at 0.7% methanol is a direct consequence of the fact that methanol-toluene mixtures are far from ideal.	Methanol	80-88	PAN0_003d1715	Moesziomyces antarcticus	63-69
24144811-8	2013	Thus, the sharp maximum of catalytic activity of C. antarctica lipase B at 0.7% methanol is a direct consequence of the fact that methanol-toluene mixtures are far from ideal.	Methanol	130-138	PAN0_003d1715	Moesziomyces antarcticus	63-69
24283275-3	2013	The methanol extract of Aralia cordata roots showed a strong inhibitory effect on the human GPAT1 activity.	Methanol	4-12	glycerol-3-phosphate acyltransferase, mitochondrial	Homo sapiens	92-97
24141135-3	2013	Cell growth and recombinant bovine chymosin production were optimized in flask cultures during methanol induction phase achieving the highest coagulant activity with low pH values, a temperature of 25 C and with the addition of sorbitol and ascorbic acid at the beginning of this period.	Methanol	95-103	chymosin	Bos taurus	35-43
24353830-6	2013	The addition of each methanol extract up to 1 mg/ml showed no cytotoxicity on 3T3-L1 adipocyte, and approximately 20% of the lipid droplet formation was suppressed with the methanol extract of BRL or SF-RNSpBRV.	Methanol	21-29	von Willebrand factor C domain-containing protein 2-like	Mus musculus	193-196
24353830-6	2013	The addition of each methanol extract up to 1 mg/ml showed no cytotoxicity on 3T3-L1 adipocyte, and approximately 20% of the lipid droplet formation was suppressed with the methanol extract of BRL or SF-RNSpBRV.	Methanol	173-181	von Willebrand factor C domain-containing protein 2-like	Mus musculus	193-196
24141135-5	2013	The enzyme activity corresponded to 53 mg/L of recombinant bovine chymosin production after 120 h of methanol induction.	Methanol	101-109	chymosin	Bos taurus	66-74
24141135-8	2013	This study indicated that P. pastoris is a suitable expression system for bioreactor based fed-batch fermentation process for the efficient production of recombinant bovine chymosin under methanol-inducible AOX1 promoter.	Methanol	188-196	chymosin	Bos taurus	173-181
24141135-8	2013	This study indicated that P. pastoris is a suitable expression system for bioreactor based fed-batch fermentation process for the efficient production of recombinant bovine chymosin under methanol-inducible AOX1 promoter.	Methanol	188-196	aldehyde oxidase 1	Bos taurus	207-211
24591742-6	2013	Then, methanol and ethyl ether were added to pick up the drug and remove the accessories of the emulsion by extraction and centrifugation.	Methanol	6-14	protein interacting with PRKCA 1	Homo sapiens	45-49
24106805-2	2013	The present constant-pH MD study of the acylated and deacylated isoforms of SP-C in a chloroform/methanol/water mixture, often used to mimic the membrane environment, shows that the loss of the acyl groups has a structural destabilizing effect and that the increase of pH promotes intraprotein contacts which contribute to the loss of helical structure in solution.	Methanol	97-105	surfactant protein C	Homo sapiens	76-80
23939954-4	2013	The Ru-CMs showed photocatalytic activity and selectivity in the oxidation of sulfides that were as high as those of the well-known [Ru(bpy)3(PF6)2] complex, because the micelles were swollen in the methanol-sulfide mixture.	Methanol	199-207	sperm associated antigen 17	Homo sapiens	142-145
23965986-0	2013	The letrozole phase 1 metabolite carbinol as a novel probe drug for UGT2B7.	Methanol	33-41	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	68-74
23965986-2	2013	We elucidated the contribution of UDP-glucuronosyltransferase (UGT) isoforms on the glucuronidation of carbinol.	Methanol	103-111	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	34-61
23965986-2	2013	We elucidated the contribution of UDP-glucuronosyltransferase (UGT) isoforms on the glucuronidation of carbinol.	Methanol	103-111	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	63-66
23965986-8	2013	We identified UGT2B7 as the predominant UGT isoform involved in carbinol glucuronidation.	Methanol	64-72	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	14-20
23965986-8	2013	We identified UGT2B7 as the predominant UGT isoform involved in carbinol glucuronidation.	Methanol	64-72	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	14-17
23965986-10	2013	In the set of 148 human livers, carbinol glucuronidation activity significantly correlated with UGT2B7 protein as determined by Western blotting (r(s) = 0.5088, P &lt; 0.0001).	Methanol	32-40	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	96-102
23965986-13	2013	Taken together, these findings suggest carbinol as a novel in vitro probe substrate for UGT2B7.	Methanol	39-47	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	88-94
24093603-1	2013	The reaction of Morita-Baylis-Hillman (MBH) alcohols with Me2PhSiBpin under the catalysis of Cu(OTf)2/pyridine in methanol has been developed.	Methanol	114-122	POU class 2 homeobox 2	Homo sapiens	93-101
24077520-3	2013	The photoelectrocatalytic activity of the APS/(P25-PTA-Au)NCM modified photoelectrode in methanol oxidation was investigated.	Methanol	89-97	SH2B adaptor protein 2	Homo sapiens	42-45
24077520-4	2013	The APS/(P25-PTA-Au)NCM modified photoelectrode showed a higher photocurrent for methanol oxidation than control photoelectrodes.	Methanol	81-89	SH2B adaptor protein 2	Homo sapiens	4-7
24302835-5	2013	OBJECTIVES: The study evaluated free radicals scavenging, antioxidant properties and intestinal alpha-glucosidase inhibitory activity in methanol extract of two varieties of Cicer arietinum Linn viz.	Methanol	137-145	alpha-glucosidase	Cicer arietinum	96-113
24523757-0	2013	Hypotensive, Angiotensin Converting Enzyme (ACE) Inhibitory and Diuretic Activities of the Aqueous-methanol Extract of Ipomoea reniformis.	Methanol	99-107	angiotensin I converting enzyme	Rattus norvegicus	13-42
24523757-0	2013	Hypotensive, Angiotensin Converting Enzyme (ACE) Inhibitory and Diuretic Activities of the Aqueous-methanol Extract of Ipomoea reniformis.	Methanol	99-107	angiotensin I converting enzyme	Rattus norvegicus	44-47
24523757-3	2013	Objective of the present study was to investigate the hypotensive, diuretic and angiotensin converting enzyme (ACE) inhibitory activities of the aqueous-methanol (30:70) crude extract of the dried aerial parts of I. reniformis (Ir.Cr.)	Methanol	153-161	angiotensin I converting enzyme	Rattus norvegicus	111-114
24012967-8	2013	RESULTS: The results showed that the methanol extract of the aerial parts of Eriosema laurentii transactivated the estrogen receptor-alpha and displayed AhR agonistic activity but was neither androgenic nor progesteronic.	Methanol	37-45	aryl hydrocarbon receptor	Rattus norvegicus	153-156
23987340-6	2013	The methanol permeability of CTS/Cs2-PTA membrane is about 5.6x10(-7), 90% lower than that of Nafion-212 membrane.	Methanol	4-12	transthyretin	Homo sapiens	29-32
23987340-7	2013	The highest selectivity factor (phi) was obtained on CTS/Cs2-PTA-5 wt% composite membrane, 1.1x10(4)/Scm(-3)s. The present study indicates the promising potential of CTS/Csx-PTA composite membrane as alternative proton exchange membranes in direct methanol fuel cells.	Methanol	248-256	transthyretin	Homo sapiens	53-56
23987340-7	2013	The highest selectivity factor (phi) was obtained on CTS/Cs2-PTA-5 wt% composite membrane, 1.1x10(4)/Scm(-3)s. The present study indicates the promising potential of CTS/Csx-PTA composite membrane as alternative proton exchange membranes in direct methanol fuel cells.	Methanol	248-256	transthyretin	Homo sapiens	166-169
23987340-7	2013	The highest selectivity factor (phi) was obtained on CTS/Cs2-PTA-5 wt% composite membrane, 1.1x10(4)/Scm(-3)s. The present study indicates the promising potential of CTS/Csx-PTA composite membrane as alternative proton exchange membranes in direct methanol fuel cells.	Methanol	248-256	NK2 homeobox 5	Homo sapiens	170-173
24066688-10	2013	The Pb(II)-containing 4-ClO4 instead directly forms a neutral amide-containing, epppa-ligated Pb(II)-OH/Pb(II)-OCH3 equilibrium mixture upon treatment with Me4NOH 5H2O in methanol.	Methanol	171-179	submaxillary gland androgen regulated protein 3B	Homo sapiens	104-115
24044700-2	2013	Electrooxidation of CH3OH (1.23 M) in a buffered aqueous solution at pH 11.5 with [(eta(6)-p-cymene)(eta(2)-N,O-(1R,2S)-cis-1-amino-2-indanol)]Ru(II)Cl (2) on edge-plane graphite exhibits an onset current at 560 mV vs NHE.	Methanol	20-25	solute carrier family 9 member C1	Homo sapiens	218-221
23811024-7	2013	DMSO only increased mRNA expression of vitellogenin-like gene, while acetone, ethanol and methanol decreased mRNA expression of three nuclear receptor (estrogen receptor-like, ecdysone-induced protein and chicken ovalbumin upstream promoter transcription factor) genes as well as of genes encoding proteins involved in genomic (prohibitin-2) and non-genomic (striatin) pathways of estrogens activity in vertebrates.	Methanol	90-98	hepatocyte nuclear factor 4 alpha	Gallus gallus	134-150
23811024-7	2013	DMSO only increased mRNA expression of vitellogenin-like gene, while acetone, ethanol and methanol decreased mRNA expression of three nuclear receptor (estrogen receptor-like, ecdysone-induced protein and chicken ovalbumin upstream promoter transcription factor) genes as well as of genes encoding proteins involved in genomic (prohibitin-2) and non-genomic (striatin) pathways of estrogens activity in vertebrates.	Methanol	90-98	prohibitin 2	Gallus gallus	328-340
24011431-8	2013	In 5-L bioreactor, the GS115-NpgA-ATX grew well and produced 6-MSA quickly until reached a high value of 2.2 g/L by methanol induction for 20 hours.	Methanol	116-124	thioredoxin X	Arabidopsis thaliana	34-37
23839943-5	2013	Methanol enhanced IFN-gamma production whereas C2-C10 alcohols reduced the release of this cytokine.	Methanol	0-8	interferon gamma	Homo sapiens	18-27
23751173-9	2013	Bioassays using different strains revealed that the variation in ADH activity and RNAi-mediated knockdown of alpha-Est7 significantly changed LC50 values for methanol.	Methanol	158-166	alpha-Esterase-7	Drosophila melanogaster	109-119
23857929-10	2013	Moreover, 1,5-DAN matrix was used to study the H/D exchange profile of the methanol-induced helical structure of beta-endorphin, and the relative protection can be explained by the polarity of residues involved in hydrogen bond formation.	Methanol	75-83	NBL1, DAN family BMP antagonist	Homo sapiens	14-17
23857929-10	2013	Moreover, 1,5-DAN matrix was used to study the H/D exchange profile of the methanol-induced helical structure of beta-endorphin, and the relative protection can be explained by the polarity of residues involved in hydrogen bond formation.	Methanol	75-83	proopiomelanocortin	Homo sapiens	113-127
23607907-10	2013	The results of the study indicate that the Stereospermum suaveolens methanol extract showed neuroprotective activity by a significant decrease in lipid peroxidation (p &lt; 0.001) and an increase in superoxide dismutase (p &lt; 0.01), catalase (p &lt; 0.01), glutathione (p &lt; 0.001), and total thiol (p &lt; 0.001) levels in extract-treated groups as compared to control group.	Methanol	68-76	catalase	Rattus norvegicus	235-243
23739162-5	2013	The extracted NAP could be easily desorbed with a mixture of methanol/sodium hydroxide aqueous solution and determined spectrofluorometrically at lambdaem = 353 nm (lambdaex = 271 nm).	Methanol	61-69	catenin, beta like 1	Mus musculus	14-17
23969473-10	2013	The methanol extract significantly and dose-dependently transactivated ERalpha at all tested doses.	Methanol	4-12	estrogen receptor 1	Homo sapiens	71-78
23793221-1	2013	A novel C-C coupled 1D-polymeric chain (1) is obtained by reaction of HgCl2 and hmp-H (2-(2-hydroxymethyl pyridine)) (1 : 1) in MeOH at ambient temperature.	Methanol	128-132	hematopoietically expressed homeobox	Homo sapiens	80-85
23843260-1	2013	Alkali-resistant osmabenzene [(SCN)2(PPh3)2Os{CHC(PPh3)CHCICH}] (2) can undergo nucleophilic aromatic substitution with MeOH or EtOH to give cine-substitution products [(SCN)2(PPh3)2Os{CHC(PPh3)CHCHCR}] (R=OMe (3), OEt(4)) in the presence of strong alkali.	Methanol	120-124	caveolin 1	Homo sapiens	37-41
23843260-1	2013	Alkali-resistant osmabenzene [(SCN)2(PPh3)2Os{CHC(PPh3)CHCICH}] (2) can undergo nucleophilic aromatic substitution with MeOH or EtOH to give cine-substitution products [(SCN)2(PPh3)2Os{CHC(PPh3)CHCHCR}] (R=OMe (3), OEt(4)) in the presence of strong alkali.	Methanol	120-124	caveolin 1	Homo sapiens	50-54
23805983-1	2013	The chlorotropy observed by NMR in this study occurred by the rapid intermolecular transfer of a chloro group between 1-chlorobenzimidazole and benzimidazole in CCl4/CH3OH/K2CO3 solution.	Methanol	166-171	C-C motif chemokine ligand 4	Homo sapiens	161-165
24369608-5	2013	In experiments, by taking biphenyl as the sample, the values of retention time in isocratic and gradient elution were measured on a C18 column by using a mixture of methanol and water as the mobile phase.	Methanol	165-173	Bardet-Biedl syndrome 9	Homo sapiens	132-135
23615730-1	2013	Reaction of SnF2 in MeOH with the appropriate neutral N- or O-donor ligands produces [SnF(2,2"-bipy)]2SnF6, [SnF(1,10-phen)]2SnF4 and [SnF2(L)] L = Me3PO, dmso or pyNO).	Methanol	20-24	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	12-16
23808953-4	2013	The hybrid system produces 5275 mumole of H2 (mumole protein)(-1) h(-1) at pH 7 in the presence of methanol as a sacrificial electron donor under white light.	Methanol	99-107	relaxin 2	Homo sapiens	42-64
23777395-2	2013	The use of methanol/water solvent allowed us to investigate the Cu(II)-HPicHA equilibria under homogeneous conditions between pH 1 and 11.	Methanol	11-19	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	126-137
23676951-1	2013	One pot reaction of hydrated chloride salts of Fe(II) and Co(II) with stoichiometric amounts of 2,2"-bipyrimidine (bpym) in a methanol-acetonitrile mixture afforded the corresponding 1D homonuclear coordination polymers, [mu-(bpym)MCl2]n. Crystal structures of both complexes are isomorphous in the highly symmetric orthorhombic space group Fddd.	Methanol	126-134	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	58-64
23494165-2	2013	The fluorescence spectra of L 1 in MeOH show an emission band centered at 300 nm.	Methanol	35-39	immunoglobulin kappa variable 1-16	Homo sapiens	28-31
23494165-9	2013	Selective "off-on-off" behavior of L 1 in methanol has also been studied.	Methanol	42-50	immunoglobulin kappa variable 1-16	Homo sapiens	35-38
23627469-4	2013	OBJECTIVE: The present study investigates the effect of methanol root extract of C. ferruginea and its active constituent amentoflavone (CF-2) on memory, oxidative stress and acetylcholinesterase (AChE) activity in scopolamine-induced amnesia.	Methanol	56-64	coagulation factor II	Mus musculus	137-141
23627469-4	2013	OBJECTIVE: The present study investigates the effect of methanol root extract of C. ferruginea and its active constituent amentoflavone (CF-2) on memory, oxidative stress and acetylcholinesterase (AChE) activity in scopolamine-induced amnesia.	Methanol	56-64	acetylcholinesterase	Mus musculus	197-201
23615730-1	2013	Reaction of SnF2 in MeOH with the appropriate neutral N- or O-donor ligands produces [SnF(2,2"-bipy)]2SnF6, [SnF(1,10-phen)]2SnF4 and [SnF2(L)] L = Me3PO, dmso or pyNO).	Methanol	20-24	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	Homo sapiens	135-142
23558183-2	2013	The effects of the methanol usage and oil flow rate on the FAME yield were investigated under the normal pressure and methanol boiling state.	Methanol	118-126	benign adult familial myoclonic epilepsy 1	Homo sapiens	59-63
23548280-13	2013	Further separation of this fraction in a less polar solvent (30:1 chloroform:methanol) resolved at least 5 lipid-containing compounds, which likely contribute to the anti-RV activity associated with bovine MFGM.	Methanol	77-85	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	206-210
23529726-1	2013	A new set of penta-coordinated copper(II) hydrazone complexes containing solvated methanol were synthesized by reacting the hydrazone ligands, 2-acetylpyridine benzoyl hydrazone (HL1) and 2-acetylpyridine thiophene-2-carboxylic acid hydrazone (HL2), with [CuCl2(DMSO)2] and characterized by different spectral methods.	Methanol	82-90	intelectin 1	Homo sapiens	179-182
23529726-1	2013	A new set of penta-coordinated copper(II) hydrazone complexes containing solvated methanol were synthesized by reacting the hydrazone ligands, 2-acetylpyridine benzoyl hydrazone (HL1) and 2-acetylpyridine thiophene-2-carboxylic acid hydrazone (HL2), with [CuCl2(DMSO)2] and characterized by different spectral methods.	Methanol	82-90	intelectin 2	Homo sapiens	244-247
23646986-4	2013	The Co(II)-Ln(III) and Ni(II)-Ln(III) complexes are crystallized in an isomorphous monoclinic space group P2(1)/c, where the Co(II) or Ni(II) ion at the high-spin state has an octahedral coordination environment with N2O2 donor atoms of 3-MeOsaltn at the equatorial sites, and one oxygen atom of the bridged acetato and a methanol oxygen atom at the two axial sites.	Methanol	322-330	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
23529657-1	2013	Alcohol dehydrogenase (ADH) catalyzes the final step in the biosynthesis of methanol from CO2.	Methanol	76-84	aldo-keto reductase family 1 member A1	Homo sapiens	0-21
23529657-1	2013	Alcohol dehydrogenase (ADH) catalyzes the final step in the biosynthesis of methanol from CO2.	Methanol	76-84	aldo-keto reductase family 1 member A1	Homo sapiens	23-26
23529657-7	2013	In the direction of formaldehyde reduction, ADH has an ordered kinetic mechanism with formaldehyde adding to enzyme first and product methanol released last.	Methanol	134-142	aldo-keto reductase family 1 member A1	Homo sapiens	44-47
23254514-7	2013	Two deep-branching alphaproteobacterial genotypes of mch responded to the addition of ambient concentrations of methanol ( 0.6 mumol methanol gsoilDW(-1)) in one of these soils.	Methanol	112-120	pro-melanin concentrating hormone	Homo sapiens	53-56
23089953-7	2013	The purified azoreductase retained nearly 100 % activity after incubating in 30 % dimethyl sulfoxide (DMSO), 30 % acetone, 30 % methanol, 20 % ethanol, 20 % isopropanol, and 10 % propanol.	Methanol	128-136	NAD(P)H quinone dehydrogenase 1	Homo sapiens	13-25
23254514-7	2013	Two deep-branching alphaproteobacterial genotypes of mch responded to the addition of ambient concentrations of methanol ( 0.6 mumol methanol gsoilDW(-1)) in one of these soils.	Methanol	133-141	pro-melanin concentrating hormone	Homo sapiens	53-56
23296916-6	2013	The optimal conditions for expression were under a final concentration of 0.5 % methanol and a time-course of 96 h. The synthesized recombinant Zea mays transglutaminase (TGZs) was purified by affinity method, its production was 4.4 mg/L, and the specific activity was 0.889 U/mg under optimal expression condition.	Methanol	80-88	transglutaminase15	Zea mays	153-169
22674731-5	2013	The n-hexane and chloroform fraction of the methanol extract of C. sadleriana exhibited remarkable COX-1 and COX-2 inhibiting effects in vitro.	Methanol	44-52	cytochrome c oxidase I, mitochondrial	Rattus norvegicus	99-104
23631356-5	2013	RESULTS: The results indicate that (50, 100 mug/mL) methanol and ethyl acetate fractionation extracts of PY not only inhibited LPS-mediated NO production and iNOS expression, but also decreased LPS-induced PGE2 production and COX-2 expression.	Methanol	52-60	nitric oxide synthase 2, inducible	Mus musculus	158-162
23631356-5	2013	RESULTS: The results indicate that (50, 100 mug/mL) methanol and ethyl acetate fractionation extracts of PY not only inhibited LPS-mediated NO production and iNOS expression, but also decreased LPS-induced PGE2 production and COX-2 expression.	Methanol	52-60	prostaglandin-endoperoxide synthase 2	Mus musculus	226-231
23631356-7	2013	LPS-induced nuclear translocation of NF-kappaB decreased significantly by the methanol extract and ethyl acetate fraction of PY.	Methanol	78-86	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	37-46
23376619-5	2013	The amount of the CAR-Fc protein to total cell protein was up to 10% by 1% methanol induction for 96h and the purity was up to 96% after protein purification.	Methanol	75-83	coxsackie virus and adenovirus receptor	Mus musculus	18-21
23391964-1	2013	The reactions of enantiopure chiral ligands (+)/(-)-4,5-pinenepyridyl-2-pyrazine (LS/LR) with CuCl2 2H2O in CH3OH/CH2Cl2 solution led to the formations of one-dimensional homochiral enantiomeric pairs with the formula [Cu(LR/S)Cl2]n 2H2O (R-1 and S-1, the isomers containing the LR and LS ligands, respectively).	Methanol	108-114	CD1b molecule	Homo sapiens	233-250
23723613-13	2013	Mean serum methanol level was 87.1 mg/dL, and correlated significantly with the mortality (53.1 +- 41 mg/dL v/s 121 +- 92 mg/dL, P value &lt; 0.05).	Methanol	11-19	dlv	Drosophila melanogaster	105-109
23511424-4	2013	The conversion of a MeOH-H2O mixture proceeds selectively to CO2/H2 gas formation under neutral conditions, thereby allowing the use of the entire hydrogen content (12% by weight).	Methanol	20-24	complement C2	Homo sapiens	61-67
23497855-2	2013	The mixed-mode Oasis WCX sorbent used in an optimised protocol allows the addition of an effective washing step with 0.5 mL of methanol, which washed out all the interferences retained by reversed-phase interactions and helped to reduce the matrix effect, while the cationic target analytes remained bound and could then be selectively eluted with recovery values near to 100%.	Methanol	127-135	cAMP responsive element binding protein 3 like 1	Homo sapiens	15-20
23404844-7	2013	In addition we show that the heteromolecular H2 S-MeOH complex, for which both S-H   O and O-H   S interactions are possible, is S-H   O bound.	Methanol	50-54	shadow of prion protein	Homo sapiens	79-92
22674731-5	2013	The n-hexane and chloroform fraction of the methanol extract of C. sadleriana exhibited remarkable COX-1 and COX-2 inhibiting effects in vitro.	Methanol	44-52	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	109-114
23898632-9	2013	Three alkylbenzene compounds can be separated and retained well on C18-sph-SiON even in the mobile phase of methanol/H2O (70/30, v/v) with 78 507 plates/m, and an excellent tailing factor (0.95) can be obtained for ethylbenzene.	Methanol	108-116	Bardet-Biedl syndrome 9	Homo sapiens	67-70
23207165-0	2013	Methanol teratogenicity in mutant mice with deficient catalase activity and transgenic mice expressing human catalase.	Methanol	0-8	catalase	Homo sapiens	54-62
23207165-4	2013	hCat mice and WTs were similarly susceptible to MeOH-initiated ophthalmic abnormalities and cleft palates.	Methanol	48-52	catalase	Homo sapiens	0-4
23634021-1	2013	The title complex, {[Cu(C21H13N5S2)]PF6 CH3CN} n , was formed immediately on adding together a methanol solution containing copper(I) ions and a methanol solution of 2,6-bis-[4-(pyridin-2-yl)thia-zol-2-yl]pyridine.	Methanol	95-103	sperm associated antigen 17	Homo sapiens	36-39
23634021-1	2013	The title complex, {[Cu(C21H13N5S2)]PF6 CH3CN} n , was formed immediately on adding together a methanol solution containing copper(I) ions and a methanol solution of 2,6-bis-[4-(pyridin-2-yl)thia-zol-2-yl]pyridine.	Methanol	145-153	sperm associated antigen 17	Homo sapiens	36-39
23411023-0	2013	AP-1 pathway-targeted inhibition of inflammatory responses in LPS-treated macrophages and EtOH/HCl-treated stomach by Archidendron clypearia methanol extract.	Methanol	141-149	jun proto-oncogene	Mus musculus	0-4
23359487-4	2013	From a methanol solution containing CNacacH (L) and Cd(OAc)(2) 2 H(2)O (M), a coordination polymer (Cd-1) in which trans-[Cd(CNacac)(2)] units are three-dimensionally linked was obtained.	Methanol	7-15	CD1c molecule	Homo sapiens	100-104
23529036-3	2013	The dichloromethane, ethanol and methanol extracts from the leaves of Rauvolfia reflexa showed potential acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, with IC50 values in the 8.49 to 52.23 g/mL range.	Methanol	33-41	acetylcholinesterase (Cartwright blood group)	Homo sapiens	127-131
23529036-3	2013	The dichloromethane, ethanol and methanol extracts from the leaves of Rauvolfia reflexa showed potential acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, with IC50 values in the 8.49 to 52.23 g/mL range.	Methanol	33-41	butyrylcholinesterase	Homo sapiens	137-158
23529036-3	2013	The dichloromethane, ethanol and methanol extracts from the leaves of Rauvolfia reflexa showed potential acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, with IC50 values in the 8.49 to 52.23 g/mL range.	Methanol	33-41	butyrylcholinesterase	Homo sapiens	160-164
23386431-0	2013	Three-axis anisotropic exchange coupling in the single-molecule magnets NEt4[Mn(III)2(5-Brsalen)2(MeOH)2M(III)(CN)6] (M=Ru, Os).	Methanol	98-102	tetraspanin 5	Homo sapiens	72-76
23398593-10	2013	The desolvated Co(II)(pybz)2 can absorb several gases such as CO2, N2, H2, and CH4 and also vapors of methanol, ethanol, benzene, and cyclohexane.	Methanol	102-110	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	15-21
24009873-0	2013	A Methanol Extract of Adansonia digitata L. Leaves Inhibits Pro-Inflammatory iNOS Possibly via the Inhibition of NF-kappaB Activation.	Methanol	2-10	nitric oxide synthase 2, inducible	Mus musculus	77-81
24009873-0	2013	A Methanol Extract of Adansonia digitata L. Leaves Inhibits Pro-Inflammatory iNOS Possibly via the Inhibition of NF-kappaB Activation.	Methanol	2-10	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	113-122
23325053-1	2013	Reaction of oxabicyclic alkenes with alkynes and organoboronic acids in the presence of Ni(cod)(2), P(t-Bu)(3), and CsF in a binary solvent toluene-methanol (1 : 3) at 75 to 85  C provided exo-5,6-disubstituted 7-oxanorbornene derivatives in good to excellent yields.	Methanol	148-156	colony stimulating factor 2	Homo sapiens	116-119
23075383-2	2013	Solvents that serve as efficient H atom donors (methanol, ethanol, isopropyl alcohol) favor products arising from a net reduction of one or more of the C-Br bonds.	Methanol	48-56	carbonyl reductase 1	Homo sapiens	152-156
23256664-2	2013	By adjusting the CO(2)-to-steam ratio in the gas feed, the H(2)/CO ratio in the produced syn-gas could be easily adjusted in a single step to the desired value of 2 for methanol and hydrocarbon synthesis.	Methanol	169-177	synemin	Homo sapiens	89-92
23298027-0	2013	Linear scaling explicitly correlated MP2-F12 and ONIOM methods for the long-range interactions of the nanoscale clusters in methanol aqueous solutions.	Methanol	124-132	tryptase pseudogene 1	Homo sapiens	37-40
23180614-3	2013	[Fe(qsal-5-OMe)(2)]Cl 2 MeOH 0.5 H(2)O (1) exhibits rare crystallographically independent high-spin and low-spin Fe(III) centres at 150 K, whereas [Fe(qsal-5-OMe)(2)]Cl  MeCN H(2)O (2) is low spin at 100 K. In both structures there are extensive pi-pi and C-H   pi interactions.	Methanol	24-28	spindlin 1	Homo sapiens	95-99
23180614-3	2013	[Fe(qsal-5-OMe)(2)]Cl 2 MeOH 0.5 H(2)O (1) exhibits rare crystallographically independent high-spin and low-spin Fe(III) centres at 150 K, whereas [Fe(qsal-5-OMe)(2)]Cl  MeCN H(2)O (2) is low spin at 100 K. In both structures there are extensive pi-pi and C-H   pi interactions.	Methanol	24-28	spindlin 1	Homo sapiens	108-112
23180614-3	2013	[Fe(qsal-5-OMe)(2)]Cl 2 MeOH 0.5 H(2)O (1) exhibits rare crystallographically independent high-spin and low-spin Fe(III) centres at 150 K, whereas [Fe(qsal-5-OMe)(2)]Cl  MeCN H(2)O (2) is low spin at 100 K. In both structures there are extensive pi-pi and C-H   pi interactions.	Methanol	24-28	spindlin 1	Homo sapiens	108-112
23160369-4	2013	The photocatalytic CO(2) to methanol conversion rate on modified graphene oxide (GO-3) is 0.172 mumol g cat(-1) h(-1) under visible light, which is six-fold higher than the pure TiO(2).	Methanol	28-36	GIT ArfGAP 1	Homo sapiens	104-110
24312878-0	2013	Antinociceptive activity and effect of methanol extracts of three salvia spp.	Methanol	39-47	sphingosine-1-phosphate phosphatase 1	Mus musculus	73-76
24117067-3	2013	In whole-cell patch clamp mode, methanol extract of Withania somnifera (mWS) induced short-lived and repeatable inward currents in all SG neurons tested (31.3 +- 8.51 pA, n = 7) using a high chloride pipette solution.	Methanol	32-40	NLR family, pyrin domain containing 3	Mus musculus	72-75
23425686-7	2013	Upon deletion of the genes encoding Yap1 or cytochrome c peroxidase, the CLS extension of cat cells on methanol was abolished.	Methanol	103-111	DNA-binding transcription factor YAP1	Saccharomyces cerevisiae S288C	36-40
23425686-7	2013	Upon deletion of the genes encoding Yap1 or cytochrome c peroxidase, the CLS extension of cat cells on methanol was abolished.	Methanol	103-111	cytochrome-c peroxidase	Saccharomyces cerevisiae S288C	44-67
24069061-4	2013	Methanol extract of BF (bark) inhibited Rho-kinase 2 (ROCK-II) enzyme activity in vitro with an IC50 of 20.29 +- 1.83  mu g/mL.	Methanol	0-8	Rho-associated coiled-coil containing protein kinase 2	Rattus norvegicus	54-61
22796768-7	2013	Stability of FDH activity was also evaluated under the various conditions, in which protein denaturation could occur by solvent treatment, such as methanol or sodium dodecyl sulfate.	Methanol	147-155	alcohol dehydrogenase 5 (class III), chi polypeptide	Homo sapiens	13-16
24077107-3	2013	In the cell culture based assay, the MeOH extract significantly transactivated estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta); in addition, the estrogen-like effects of both, DCM and MeOH extracts, could be inhibited in vitro by the pure ER antagonist ICI 182,780, indicating that these effects were primarily mediated through ERs.	Methanol	37-41	estrogen receptor 2	Rattus norvegicus	117-139
22949063-1	2013	The structure and thermodynamic properties of the 2, 4-dinitroimidazole complex with methanol were investigated using the B3LYP and MP2(full) methods with the 6-31++G(2d,p) and 6-311++G(3df,2p) basis sets.	Methanol	85-93	tryptase pseudogene 1	Homo sapiens	132-135
24250718-2	2013	This study investigated the effects of methanol extracts of A. apiacea Hance (MEAH) on the induction of inducible nitric oxide synthase (iNOS) and proinflammatory mediators by lipopolysaccharide (LPS) in Raw264.7 macrophage cells and also evaluated the in vivo effect of MEAH on carrageenan-induced paw edema in rats.	Methanol	39-47	nitric oxide synthase 2, inducible	Mus musculus	137-141
23724459-10	2013	Proper CPS staining required tissue fixation in a mixture of methanol, acetone and water (2:2:1 v/v) as opposed to 4% paraformaldehyde.	Methanol	61-69	carbamoyl-phosphate synthase 1	Rattus norvegicus	7-10
24077107-3	2013	In the cell culture based assay, the MeOH extract significantly transactivated estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta); in addition, the estrogen-like effects of both, DCM and MeOH extracts, could be inhibited in vitro by the pure ER antagonist ICI 182,780, indicating that these effects were primarily mediated through ERs.	Methanol	37-41	estrogen receptor 1	Rattus norvegicus	104-111
24077107-3	2013	In the cell culture based assay, the MeOH extract significantly transactivated estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta); in addition, the estrogen-like effects of both, DCM and MeOH extracts, could be inhibited in vitro by the pure ER antagonist ICI 182,780, indicating that these effects were primarily mediated through ERs.	Methanol	37-41	estrogen receptor 2	Rattus norvegicus	141-147
24077107-3	2013	In the cell culture based assay, the MeOH extract significantly transactivated estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta); in addition, the estrogen-like effects of both, DCM and MeOH extracts, could be inhibited in vitro by the pure ER antagonist ICI 182,780, indicating that these effects were primarily mediated through ERs.	Methanol	206-210	estrogen receptor 1	Rattus norvegicus	104-111
24077107-3	2013	In the cell culture based assay, the MeOH extract significantly transactivated estrogen receptor alpha (ERalpha) and estrogen receptor beta (ERbeta); in addition, the estrogen-like effects of both, DCM and MeOH extracts, could be inhibited in vitro by the pure ER antagonist ICI 182,780, indicating that these effects were primarily mediated through ERs.	Methanol	206-210	estrogen receptor 2	Rattus norvegicus	141-147
22935729-7	2012	In sodium acetate (100 muM)-modified methanol solutions, significant changes in degrees of association (ranging from 4% to 25%) and selectivities (ranging from non-selective to 4.2:1 preference) were observed.	Methanol	37-45	latexin	Homo sapiens	23-26
24640083-0	2013	[Features of dyslipidemia development and insulin resistance in female workers engaged in methanol and formaldehyde production].	Methanol	90-98	insulin	Homo sapiens	42-49
24640084-2	2013	Workers exposed to methanol demonstrate prevalence of homozygous type of tumor necrosis factor (TNF) gene and heterozygous variant of cytochrome 450 gene, reliably increased vs reference group.	Methanol	19-27	tumor necrosis factor	Homo sapiens	73-94
24640084-2	2013	Workers exposed to methanol demonstrate prevalence of homozygous type of tumor necrosis factor (TNF) gene and heterozygous variant of cytochrome 450 gene, reliably increased vs reference group.	Methanol	19-27	tumor necrosis factor	Homo sapiens	96-99
23516113-9	2012	ALT, ALP, AST and urea values were significantly increased respectively at 100mg/kg bw/day and 400mg/kg bw/day methanol extract.	Methanol	111-119	glutamic pyruvic transaminase, soluble	Mus musculus	0-3
23141910-1	2012	In the course of ongoing research on protein tyrosine phosphatase 1B (PTP1B) inhibitory compounds from Antarctic lichens, four new diterpene furanoids, hueafuranoids A-D (1-4) have been isolated from the MeOH extract of Antarctic lichen Huea sp.	Methanol	204-208	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	37-68
23141910-1	2012	In the course of ongoing research on protein tyrosine phosphatase 1B (PTP1B) inhibitory compounds from Antarctic lichens, four new diterpene furanoids, hueafuranoids A-D (1-4) have been isolated from the MeOH extract of Antarctic lichen Huea sp.	Methanol	204-208	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	70-75
23526115-3	2012	Experiments with cytochrome c (Cytc) demonstrated that methanol induced conformational shifts previously observed with ESI are also easily observed with liquid DESI.	Methanol	55-63	cytochrome c, somatic	Homo sapiens	17-29
23516113-9	2012	ALT, ALP, AST and urea values were significantly increased respectively at 100mg/kg bw/day and 400mg/kg bw/day methanol extract.	Methanol	111-119	transmembrane protease, serine 11d	Mus musculus	10-13
22622367-6	2012	Inhibition of the human serotonin transporter by the methanol extract was even more effective (EC(50) 1.4 mug/ml).	Methanol	53-61	solute carrier family 6 member 4	Homo sapiens	24-45
23204928-8	2012	In negative mode as well, the maximum number of MS2 features was detected in methanol/chloroform/water and acetone/isopropanol extracts.	Methanol	77-85	MS2	Homo sapiens	48-51
22763911-2	2012	On clean gamma-Al(2)O(3) (100) and (110) surfaces, DME and methanol preferentially interact with Al3 and Al1 of the gamma-Al(2)O(3)(110) and (100) surfaces, respectively.	Methanol	59-67	ephrin A5	Homo sapiens	105-108
23205139-0	2012	Bak is a key molecule in apoptosis induced by methanol extracts of Codonopsis lanceolata and Tricholoma matsutake in HSC-2 human oral cancer cells.	Methanol	46-54	BCL2 antagonist/killer 1	Homo sapiens	0-3
22810212-0	2012	Erythropoietin treatment for methanol optic neuropathy.	Methanol	29-37	erythropoietin	Homo sapiens	0-14
22810212-1	2012	BACKGROUND: To present the effect of erythropoietin for the treatment of methanol optic neuropathy.	Methanol	73-81	erythropoietin	Homo sapiens	37-51
22810212-2	2012	METHODS: Two patients with methanol optic neuropathy were treated with 10,000 IU of intravenous erythropoietin twice a day for 3 days, 500 mg of methylprednisolone twice a day for 5 days (followed by 2 weeks of oral prednisolone [1 mg/kg per day]), and daily doses of vitamin B12, vitamin B6, and folic acid for 1 month.	Methanol	27-35	erythropoietin	Homo sapiens	96-110
22810212-6	2012	CONCLUSION: Intravenous erythropoietin may be an effective adjuvant when combined with current treatment for patients with methanol optic neuropathy.	Methanol	123-131	erythropoietin	Homo sapiens	24-38
23413565-6	2012	The administered methanol extracts with the highest antioxidant potential showed a significant dose-dependent hepatoprotective action against CCl4-induced liver damage in both decreasing the levels of liver transaminases and bilirubin and in reducing the extent of morphological malformations of the liver.	Methanol	17-25	C-C motif chemokine ligand 4	Rattus norvegicus	142-146
23110599-4	2012	Similarly, the dizinc complex, [NMe4]2[Zn2(ccdp)(mu-OAc)] CH3OH (2), was synthesized from Zn(OAc)2 2H2O and H5ccdp in the presence of NMe4OH at ambient temperature in methanol.	Methanol	167-175	NME/NM23 nucleoside diphosphate kinase 4	Homo sapiens	32-36
22978659-2	2012	OBJECTIVES: The present investigation was to demonstrate the protective effect of the methanol extract of B. nigra leaves against D-galactosamine (D-GalN)-induced hepatic and nephrotoxicity in Wistar rats.	Methanol	86-94	galanin and GMAP prepropeptide	Rattus norvegicus	149-153
22978659-12	2012	CONCLUSIONS: The crude methanol extract of B. nigra leaf lacks inherent toxicity and exhibits hepatic and nephroprotective effects against D-GalN-induced toxicity in Wistar rats.	Methanol	23-31	galanin and GMAP prepropeptide	Rattus norvegicus	141-145
23121620-2	2012	Single-crystal X-ray structural analysis was carried out for (PPh4)2[MN(CN)4L] (M = Re, L = MeOH, EtOH, or acetone; M = Tc, L = MeOH) and (PPh4)2[ReN(CN)4].	Methanol	92-96	potassium two pore domain channel subfamily K member 3	Homo sapiens	62-66
23121620-2	2012	Single-crystal X-ray structural analysis was carried out for (PPh4)2[MN(CN)4L] (M = Re, L = MeOH, EtOH, or acetone; M = Tc, L = MeOH) and (PPh4)2[ReN(CN)4].	Methanol	128-132	potassium two pore domain channel subfamily K member 3	Homo sapiens	62-66
23110456-8	2012	RESULTS: CJ methanol extract reduced NO release via iNOS protein inhibition.	Methanol	12-20	nitric oxide synthase 2, inducible	Mus musculus	52-56
23088314-1	2012	Water-soluble fac-[Re(CO)(3)(L,L"-Bid)(X)] (L,L"-Bid = tropolonato, X = H(2)O, methanol) complexes have been synthesized, and the aqua and methanol substitution reactions were investigated in water (pH range 6.3-10.0) and methanol, respectively, and compared.	Methanol	79-87	FA complementation group C	Homo sapiens	14-17
23088314-1	2012	Water-soluble fac-[Re(CO)(3)(L,L"-Bid)(X)] (L,L"-Bid = tropolonato, X = H(2)O, methanol) complexes have been synthesized, and the aqua and methanol substitution reactions were investigated in water (pH range 6.3-10.0) and methanol, respectively, and compared.	Methanol	139-147	FA complementation group C	Homo sapiens	14-17
23088314-1	2012	Water-soluble fac-[Re(CO)(3)(L,L"-Bid)(X)] (L,L"-Bid = tropolonato, X = H(2)O, methanol) complexes have been synthesized, and the aqua and methanol substitution reactions were investigated in water (pH range 6.3-10.0) and methanol, respectively, and compared.	Methanol	139-147	FA complementation group C	Homo sapiens	14-17
23088314-0	2012	Coordinated aqua vs methanol substitution kinetics in fac-Re(I) tricarbonyl tropolonato complexes.	Methanol	20-28	FA complementation group C	Homo sapiens	54-57
23110456-12	2012	CONCLUSIONS: Our results demonstrated the anti-inflammatory activity of CJ methanol extract and its possible underlying mechanisms that involve modulation of IkappaBalpha, MAPK, and STAT1 activities.	Methanol	75-83	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	158-170
23110456-12	2012	CONCLUSIONS: Our results demonstrated the anti-inflammatory activity of CJ methanol extract and its possible underlying mechanisms that involve modulation of IkappaBalpha, MAPK, and STAT1 activities.	Methanol	75-83	mitogen-activated protein kinase 1	Mus musculus	172-176
23110456-12	2012	CONCLUSIONS: Our results demonstrated the anti-inflammatory activity of CJ methanol extract and its possible underlying mechanisms that involve modulation of IkappaBalpha, MAPK, and STAT1 activities.	Methanol	75-83	signal transducer and activator of transcription 1	Mus musculus	182-187
22985398-10	2012	MMP-9 and MCP-1 activities were markedly diminished with methanol extract (RM), n-hexane fraction (RH), and CA in RAW 264.7 cells.	Methanol	57-65	matrix metallopeptidase 9	Mus musculus	0-5
22898785-0	2012	Synergistic effect of ZnS outer layers and electrolyte methanol content on efficiency in TiO2/CdS/CdSe sensitized solar cells.	Methanol	55-63	CDP-diacylglycerol synthase 1	Homo sapiens	94-97
22898799-2	2012	They exhibit a significantly enhanced catalytic activity for C-1 molecules (CO, CH(3)OH, HCOOH).	Methanol	80-87	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	61-64
22940243-0	2012	Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1.	Methanol	0-8	Rous sarcoma oncogene	Mus musculus	130-133
22940243-0	2012	Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1.	Methanol	0-8	spleen tyrosine kinase	Mus musculus	134-137
22940243-0	2012	Methanol extract of Osbeckia stellata suppresses lipopolysaccharide- and HCl/ethanol-induced inflammatory responses by inhibiting Src/Syk and IRAK1.	Methanol	0-8	interleukin-1 receptor-associated kinase 1	Mus musculus	142-147
23139128-2	2012	The methanol extract showed a potent inhibitory activity against PTP1B and RLAR.	Methanol	4-12	protein tyrosine phosphatase, non-receptor type 1	Rattus norvegicus	65-70
22775148-8	2012	Furthermore, basal (fasting) values of dimethyl sulfide and values of methanol in breath gas were inversely correlated with phenotype characteristics such as homeostasis model assessment of insulin resistance index (R = -0.538; P = 0.0002, P(corrected) = 0.0034) and pregestational body mass index (R = -0.433; P = 0.0013, P(corrected) = 0.022).	Methanol	70-78	insulin	Homo sapiens	190-197
22985398-10	2012	MMP-9 and MCP-1 activities were markedly diminished with methanol extract (RM), n-hexane fraction (RH), and CA in RAW 264.7 cells.	Methanol	57-65	chemokine (C-C motif) ligand 2	Mus musculus	10-15
22924490-5	2012	This LC-MS3 method made it possible to detect the homologues without the effect of matrix; therefore, high sensitive analysis was established, and then, the MS3 makes it possible to extract from plants with methanol only.	Methanol	207-215	MS3	Homo sapiens	8-11
22924490-5	2012	This LC-MS3 method made it possible to detect the homologues without the effect of matrix; therefore, high sensitive analysis was established, and then, the MS3 makes it possible to extract from plants with methanol only.	Methanol	207-215	MS3	Homo sapiens	157-160
22584156-7	2012	Methanol and ethanol were tested for their relative ability to permeabilize cells and detect PU.1.	Methanol	0-8	spleen focus forming virus (SFFV) proviral integration oncogene	Mus musculus	93-97
22869008-0	2012	Strongly visible-light responsive plasmonic shaped AgX:Ag (X = Cl, Br) nanoparticles for reduction of CO2 to methanol.	Methanol	109-117	UDP-N-acetylglucosamine pyrophosphorylase 1	Homo sapiens	51-54
22869008-5	2012	For example, reduction of CO(2) under visible light irradiation with the assistance of the anisotropic AgX:Ag nanoparticles yields as much as 100 mumol methanol in the products.	Methanol	152-160	UDP-N-acetylglucosamine pyrophosphorylase 1	Homo sapiens	103-106
23351720-10	2012	The methanol extract also showed antioxidant activities in DPPH (IC50 = 76 mug/ml) and FRAP assays (1.4 mmol ferrous ion equivalent/g extract).	Methanol	4-12	mechanistic target of rapamycin kinase	Homo sapiens	87-91
23140017-10	2012	The results indicate that methanol extracts inhibit the growth of human breast cancer cells partially through the inhibition of metallo proteinases MMP-2 and MMP-9 activities.	Methanol	26-34	matrix metallopeptidase 2	Homo sapiens	148-153
23140017-10	2012	The results indicate that methanol extracts inhibit the growth of human breast cancer cells partially through the inhibition of metallo proteinases MMP-2 and MMP-9 activities.	Methanol	26-34	matrix metallopeptidase 9	Homo sapiens	158-163
22752086-6	2012	This revealed that the methanol extract increased the levels of p21 and this may have caused cell cycle attenuation.	Methanol	23-31	H3 histone pseudogene 16	Homo sapiens	64-67
22752086-8	2012	In summary, the methanol extract and the derivative fraction F2 of S. spinosa showed anti-neoplastic effects in HL-60 cells and CYP1A1 activation in estrogen receptor-positive MCF-7 breast cancer cells but not in estrogen-negative MDA-MB231 breast cancer cells.	Methanol	16-24	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	128-134
22472102-7	2012	Reduction of gene expression and CYP1 enzyme activities by methanol (0.05% v/v) in zebrafish larvae was partially reversed by co-exposure with Aroclor 1254 (100 mug L(-1)).	Methanol	59-67	peptidylprolyl isomerase Aa (cyclophilin A)	Danio rerio	33-37
22873405-2	2012	Most often, protein production is under the control of the strong methanol-inducible aox1 promoter.	Methanol	66-74	aldehyde oxidase 1	Homo sapiens	85-89
22873405-13	2012	During the methanol fed-batch phase, induction of vacuolar proteases (e.g. strong increase of APR1) and constitutive autophagic processes were observed.	Methanol	11-19	MAGE family member H1	Homo sapiens	94-98
22859731-6	2012	With hydrogen as the electron donor, strain B10(T) produced methane by reducing methanol.	Methanol	80-88	ectonucleotide pyrophosphatase/phosphodiesterase 3	Homo sapiens	44-47
22246045-6	2012	By mixing water with methanol, a refolding of cytochrome C is observed as the water percentage increases in the plume due to the preponderant evaporation of volatile methanol.	Methanol	21-29	cytochrome c, somatic	Homo sapiens	46-58
22698910-4	2012	AIM OF THE STUDY: This study evaluated the antinociceptive effect of the methanol extract of I. balsamina flowers (MIB).	Methanol	73-81	MIB E3 ubiquitin protein ligase 1	Mus musculus	115-118
22775414-10	2012	Only 43.47% inhibition of angiotensin converting enzyme (ACE) was shown by methanol extract.	Methanol	75-83	angiotensin I converting enzyme	Homo sapiens	26-55
22775414-10	2012	Only 43.47% inhibition of angiotensin converting enzyme (ACE) was shown by methanol extract.	Methanol	75-83	angiotensin I converting enzyme	Homo sapiens	57-60
22246045-6	2012	By mixing water with methanol, a refolding of cytochrome C is observed as the water percentage increases in the plume due to the preponderant evaporation of volatile methanol.	Methanol	166-174	cytochrome c, somatic	Homo sapiens	46-58
22776436-2	2012	In this study, the hepatoprotective effects of the methanol extract of SAME was evaluated against carbon tetrachloride (CCl4)-induced liver injuries in rats.	Methanol	51-59	C-C motif chemokine ligand 4	Rattus norvegicus	120-124
22713963-3	2012	Ethanol, methanol and acetone extract of Kutajghan vati demonstrated good antimicrobial activity and thus can form the basis for the development of a novel antibacterial formulation.	Methanol	9-17	vesicle amine transport 1	Homo sapiens	51-55
22625429-0	2012	Pichia pastoris 14-3-3 regulates transcriptional activity of the methanol inducible transcription factor Mxr1 by direct interaction.	Methanol	65-73	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	105-109
22625429-1	2012	The zinc-finger transcription factor, Mxr1 activates methanol utilization and peroxisome biogenesis genes in the methylotrophic yeast, Pichia pastoris.	Methanol	53-61	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	38-42
22160734-0	2012	A comparative theoretical study for the methanol dehydrogenation to CO over Pt3 and PtAu2 clusters.	Methanol	40-48	zinc finger protein 135	Homo sapiens	76-79
22511469-4	2012	The methanol-to-hydrocarbons (MTH) process is a key step in such routes, and can be tuned into production of gasoline-rich (methanol to gasoline; MTG) or olefin-rich (methanol to olefins; MTO) product mixtures by proper choice of catalyst and reaction conditions.	Methanol	4-12	serine protease 3	Homo sapiens	146-149
21937533-6	2012	The treatment with methanol exhibited a significant increase in serum hepatic and renal biochemical parameters (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, bilirubin, urea, and creatinine).	Methanol	19-27	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	138-164
21937533-8	2012	However, hepatic and renal antioxidant enzymes namely superoxide dismutase, catalase, and glutathione peroxidase were significantly decreased in methanol-treated animals as compared to controls.	Methanol	145-153	catalase	Rattus norvegicus	76-84
22549334-5	2012	The catalytic activity of both composites for the synthesis of methanol from syn gas is evaluated.	Methanol	63-71	synemin	Homo sapiens	50-53
22511469-4	2012	The methanol-to-hydrocarbons (MTH) process is a key step in such routes, and can be tuned into production of gasoline-rich (methanol to gasoline; MTG) or olefin-rich (methanol to olefins; MTO) product mixtures by proper choice of catalyst and reaction conditions.	Methanol	124-132	serine protease 3	Homo sapiens	146-149
22511469-4	2012	The methanol-to-hydrocarbons (MTH) process is a key step in such routes, and can be tuned into production of gasoline-rich (methanol to gasoline; MTG) or olefin-rich (methanol to olefins; MTO) product mixtures by proper choice of catalyst and reaction conditions.	Methanol	124-132	serine protease 3	Homo sapiens	146-149
22169927-2	2012	Optimal conditions to fabricate PCL/SF (50/50) blend nanofiber were established for electrospinning using formic acid as a cosolvent and three-dimensional (3D) PCL/SF blend nanofibrous scaffolds were prepared by a modified electrospinning process using methanol coagulation bath.	Methanol	253-261	PHD finger protein 1	Homo sapiens	32-38
22676291-3	2012	RESULTS: Gel electrophoresis analysis revealed that Ca(NO3)2-methanol, Ca(NO3)2-ethanol, or CaCl2-methanol treatments produced more lower molecular weights of silk fibroin than CaCl2-ethanol.	Methanol	61-69	fibroin light chain	Bombyx mori	164-171
22575975-2	2012	METHODS: Initially, the crude water and methanol extracts were probed for their capacity to trigger immune cells" NADPH oxidase and MPO-dependent activities as measured by lucigenin- and luminol-amplified chemiluminescence, respectively; as compared to receptor-dependent (serum opsonised zymosan- OPZ) or receptor-independent phorbol myristerate acetate (PMA).	Methanol	40-48	myeloperoxidase	Homo sapiens	132-135
22548477-2	2012	The copper-catalyzed reaction between bis(pinacolato)diboron (B2pin2) and aryl-substituted silylacetylenes in the presence of MeOH resulted in double syn addition of the pinacolboronate moiety (Bpin) and H across the triple bond with complete selectivity.	Methanol	126-130	synemin	Homo sapiens	150-153
22419824-11	2012	Chl binding analyses of BoWSCP-His revealed that the BoWSCP-His bound both Chl a and Chl b with almost the same affinity in 40% methanol solution, although the native BoWSCP had a higher content of Chl a.	Methanol	128-136	kunitz-type trypsin inhibitor-like 1 protein	Brassica oleracea	53-59
22234458-3	2012	The solvent polarity, described through polarizability (Deltaf) of dielectric continuum theory, could universally describe both tau(av)/tau(max) and eta/eta(max) through the relation, [Formula: see text] with X = tau(av)/tau(max) or eta/eta(max), (subscript OH represents corresponding values for alcohols) for alcohol solutions of methanol, ethanol and 1-propanol at room temperature.	Methanol	332-340	endothelin receptor type A	Homo sapiens	149-152
22234458-3	2012	The solvent polarity, described through polarizability (Deltaf) of dielectric continuum theory, could universally describe both tau(av)/tau(max) and eta/eta(max) through the relation, [Formula: see text] with X = tau(av)/tau(max) or eta/eta(max), (subscript OH represents corresponding values for alcohols) for alcohol solutions of methanol, ethanol and 1-propanol at room temperature.	Methanol	332-340	endothelin receptor type A	Homo sapiens	153-156
22234458-3	2012	The solvent polarity, described through polarizability (Deltaf) of dielectric continuum theory, could universally describe both tau(av)/tau(max) and eta/eta(max) through the relation, [Formula: see text] with X = tau(av)/tau(max) or eta/eta(max), (subscript OH represents corresponding values for alcohols) for alcohol solutions of methanol, ethanol and 1-propanol at room temperature.	Methanol	332-340	endothelin receptor type A	Homo sapiens	153-156
22234458-3	2012	The solvent polarity, described through polarizability (Deltaf) of dielectric continuum theory, could universally describe both tau(av)/tau(max) and eta/eta(max) through the relation, [Formula: see text] with X = tau(av)/tau(max) or eta/eta(max), (subscript OH represents corresponding values for alcohols) for alcohol solutions of methanol, ethanol and 1-propanol at room temperature.	Methanol	332-340	endothelin receptor type A	Homo sapiens	153-156
22419824-11	2012	Chl binding analyses of BoWSCP-His revealed that the BoWSCP-His bound both Chl a and Chl b with almost the same affinity in 40% methanol solution, although the native BoWSCP had a higher content of Chl a.	Methanol	128-136	kunitz-type trypsin inhibitor-like 1 protein	Brassica oleracea	53-59
22301678-9	2012	On the other hand, the latter Co(II) complexes showed a seven-coordinate face-capped octahedron with one amine nitrogen, three pyridyl nitrogens, two pivalamide carbonyl oxygens and MeCN or MeOH.	Methanol	190-194	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	30-36
22416024-3	2012	The present studies demonstrate that (Me)OH is readily oxidised by an intramolecular PET mechanism to form the hydrogen-bonded phenoxyl-N-methylbenzimidazolium system ((Me)OH)(.+) , whereas oxidation of (pMe)OH occurs by intermolecular PET, affording the neutral phenoxyl benzimidazole ((pMe)O)(.)	Methanol	37-43	cystatin B	Homo sapiens	204-207
22416024-3	2012	The present studies demonstrate that (Me)OH is readily oxidised by an intramolecular PET mechanism to form the hydrogen-bonded phenoxyl-N-methylbenzimidazolium system ((Me)OH)(.+) , whereas oxidation of (pMe)OH occurs by intermolecular PET, affording the neutral phenoxyl benzimidazole ((pMe)O)(.)	Methanol	37-43	cystatin B	Homo sapiens	288-291
22416024-5	2012	The deprotonations of (Me)OH and (pMe)OH yield the corresponding phenolate species ((Me)O)(-) and ((pMe)O)(-), respectively, whilst that of the previously reported (H)OH (analogous to (Me)OH but lacking the N-methyl group) produces an unprecedented hydrogen-bonded phenol benzimidazolate species, as evidenced by its X-ray structure.	Methanol	22-28	cystatin B	Homo sapiens	34-37
22416024-5	2012	The deprotonations of (Me)OH and (pMe)OH yield the corresponding phenolate species ((Me)O)(-) and ((pMe)O)(-), respectively, whilst that of the previously reported (H)OH (analogous to (Me)OH but lacking the N-methyl group) produces an unprecedented hydrogen-bonded phenol benzimidazolate species, as evidenced by its X-ray structure.	Methanol	22-28	cystatin B	Homo sapiens	100-103
22439732-6	2012	The fact that the I(alc) state populates at low concentrations of methanol and ethanol and the fact that the extent of chain expansion in this state approaches that of the U(B) state indicate a definite influence of electrostatic repulsion severed by the low dielectric of the water/alcohol mixture.	Methanol	66-74	allantoicase	Homo sapiens	20-23
22445674-3	2012	Purification of the methanol extract of Paulownia tomentosa fruits yielded potent hAChE and BChE inhibitory flavonoids (1-9).	Methanol	20-28	acetylcholinesterase (Cartwright blood group)	Homo sapiens	82-87
22260520-4	2012	Thus, a metalloenzyme-inspired polymeric imidazole Pd catalyst (MEPI-Pd) was readily prepared by the coordinative convolution of (NH(4))(2)PdCl(4) and poly[(N-vinylimidazole)-co-(N-isopropylacrylamide)(5)] in a methanol-water solution at 80  C for 30 min.	Methanol	211-219	serpin family I member 2	Homo sapiens	64-68
22344389-2	2012	Via ship-in-a-bottle synthesis, adamantane and methyladamantanes could be produced from methanol conversion in the cage of 8-ring SAPO catalysts under very mild reaction conditions.	Methanol	88-96	inositol polyphosphate-5-phosphatase D	Homo sapiens	4-8
22104276-3	2012	The electrochemical catalytic activity for methanol oxidation of PtRu/MWCNTs and commercial PtRu/C (E-TEK) is comparatively investigated using cyclic voltammetry and chronoamperometry.	Methanol	43-51	TEK receptor tyrosine kinase	Homo sapiens	102-105
22129629-5	2012	Due to the presence of different number of hydroxyethyl groups in the molecule of PDI 1 and PDI 2, the self-assembly of the two molecules in methanol and n-hexane results in nanostructures with distinctly different morphology as follows: nanobelts and nanoleaves for PDI 1 and nanobelt dendrites and nanosheets for PDI 2, respectively.	Methanol	141-149	peptidyl arginine deiminase 1	Homo sapiens	82-87
22129629-5	2012	Due to the presence of different number of hydroxyethyl groups in the molecule of PDI 1 and PDI 2, the self-assembly of the two molecules in methanol and n-hexane results in nanostructures with distinctly different morphology as follows: nanobelts and nanoleaves for PDI 1 and nanobelt dendrites and nanosheets for PDI 2, respectively.	Methanol	141-149	peptidyl arginine deiminase 2	Homo sapiens	92-97
22129629-5	2012	Due to the presence of different number of hydroxyethyl groups in the molecule of PDI 1 and PDI 2, the self-assembly of the two molecules in methanol and n-hexane results in nanostructures with distinctly different morphology as follows: nanobelts and nanoleaves for PDI 1 and nanobelt dendrites and nanosheets for PDI 2, respectively.	Methanol	141-149	peptidyl arginine deiminase 1	Homo sapiens	267-272
22129629-5	2012	Due to the presence of different number of hydroxyethyl groups in the molecule of PDI 1 and PDI 2, the self-assembly of the two molecules in methanol and n-hexane results in nanostructures with distinctly different morphology as follows: nanobelts and nanoleaves for PDI 1 and nanobelt dendrites and nanosheets for PDI 2, respectively.	Methanol	141-149	peptidyl arginine deiminase 2	Homo sapiens	315-320
22129629-7	2012	Furthermore, the conductivity of the aggregates of either PDI 1 or PDI 2 from methanol is more than ca.	Methanol	78-86	peptidyl arginine deiminase 1	Homo sapiens	58-63
22129629-7	2012	Furthermore, the conductivity of the aggregates of either PDI 1 or PDI 2 from methanol is more than ca.	Methanol	78-86	peptidyl arginine deiminase 2	Homo sapiens	67-72
22508581-7	2012	In addition, methanol exposure greatly up-regulated the mRNA expression level of five Cyp genes, which were Cyp304a1, Cyp9f2, Cyp28a5, Cyp4d2, and Cyp4e2.	Methanol	13-21	Cyp304a1	Drosophila melanogaster	108-116
22508581-7	2012	In addition, methanol exposure greatly up-regulated the mRNA expression level of five Cyp genes, which were Cyp304a1, Cyp9f2, Cyp28a5, Cyp4d2, and Cyp4e2.	Methanol	13-21	Cyp9f2	Drosophila melanogaster	118-124
22508581-7	2012	In addition, methanol exposure greatly up-regulated the mRNA expression level of five Cyp genes, which were Cyp304a1, Cyp9f2, Cyp28a5, Cyp4d2, and Cyp4e2.	Methanol	13-21	Cyp28a5	Drosophila melanogaster	126-133
22508581-7	2012	In addition, methanol exposure greatly up-regulated the mRNA expression level of five Cyp genes, which were Cyp304a1, Cyp9f2, Cyp28a5, Cyp4d2, and Cyp4e2.	Methanol	13-21	Cytochrome P450-4d2	Drosophila melanogaster	135-141
22508581-7	2012	In addition, methanol exposure greatly up-regulated the mRNA expression level of five Cyp genes, which were Cyp304a1, Cyp9f2, Cyp28a5, Cyp4d2, and Cyp4e2.	Methanol	13-21	Cytochrome P450-4e2	Drosophila melanogaster	147-153
22091847-3	2012	SBWC separation of sunscreens was also achieved on the XTerra MS C18 and the XBridge C18 columns using pure water at 230-250 C. Methanol was eliminated in the SBWC methods developed in this study.	Methanol	128-136	Bardet-Biedl syndrome 9	Homo sapiens	65-68
22091847-3	2012	SBWC separation of sunscreens was also achieved on the XTerra MS C18 and the XBridge C18 columns using pure water at 230-250 C. Methanol was eliminated in the SBWC methods developed in this study.	Methanol	128-136	Bardet-Biedl syndrome 9	Homo sapiens	85-88
22574444-1	2012	MeOH extracts of 37 herbs were tested in screening experiments for rat intestinal alpha-glucosidase.	Methanol	0-4	sucrase-isomaltase	Homo sapiens	82-99
22394381-1	2012	Carbinol-tethered octalin-diols (1), which differ only by the C11 configuration at the angular position, were transformed selectively to three types of structurally unrelated original scaffolds such as unsymmetrical octahydroanthracenes (5/7), furofuranes (6), or spirans (8/9) via a two-step protocol.	Methanol	0-8	aldo-keto reductase family 1 member C4	Homo sapiens	62-65
22293124-0	2012	Methanol extract of Antrodia cinnamomea mycelia induces phenotypic and functional differentiation of HL60 into monocyte-like cells via an ERK/CEBP-beta signaling pathway.	Methanol	0-8	mitogen-activated protein kinase 1	Homo sapiens	138-141
22293124-0	2012	Methanol extract of Antrodia cinnamomea mycelia induces phenotypic and functional differentiation of HL60 into monocyte-like cells via an ERK/CEBP-beta signaling pathway.	Methanol	0-8	CCAAT enhancer binding protein alpha	Homo sapiens	142-146
22257634-8	2012	There were 10 decreased expression ones, such as glyceraldehyde-3-phosphate dehydrogenase, recoverin, ATP synthase alpha subunit in rats with methanol toxicity.	Methanol	142-150	recoverin	Rattus norvegicus	91-100
22197056-5	2012	Silica deposition was performed by simply adding tetraethoxysilane to a water/methanol dispersion of PSt/P(St-CPEM)(theta)-g-PDMAEMA.	Methanol	78-86	sulfotransferase family 1A member 1	Homo sapiens	101-104
22093905-3	2012	We showed a growth inhibition effect, which increased with the p53 protein expression level in recombinant Mut(s)  (methanol utilization slow) strain of Pichia.	Methanol	116-124	tumor protein p53	Homo sapiens	63-66
22145792-5	2012	ATM adducts and unreacted ATM are eluted from the microreactor with less than 40 muL of methanol and directly analyzed by nanospray Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS).	Methanol	88-96	ATM serine/threonine kinase	Homo sapiens	0-3
22145792-5	2012	ATM adducts and unreacted ATM are eluted from the microreactor with less than 40 muL of methanol and directly analyzed by nanospray Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS).	Methanol	88-96	ATM serine/threonine kinase	Homo sapiens	26-29
22100492-7	2012	Moreover, it appeared that certain components of the methanol extract may suppress CYP1A1 expression.	Methanol	53-61	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	83-89
22056335-6	2012	Treatment of the MeOH:water (80:20) extract induced DNA fragmentation and poly(ADP-ribose) polymerase (PARP) cleavage.	Methanol	17-21	poly(ADP-ribose) polymerase 1	Homo sapiens	74-101
22056335-6	2012	Treatment of the MeOH:water (80:20) extract induced DNA fragmentation and poly(ADP-ribose) polymerase (PARP) cleavage.	Methanol	17-21	poly(ADP-ribose) polymerase 1	Homo sapiens	103-107
22056335-7	2012	Increased levels of Bax and cytosolic cytochrome C and decreased levels of Bcl2 were also observed in MeOH:water (80:20) treated MCF-7 cells.	Methanol	102-106	BCL2 associated X, apoptosis regulator	Homo sapiens	20-23
22056335-7	2012	Increased levels of Bax and cytosolic cytochrome C and decreased levels of Bcl2 were also observed in MeOH:water (80:20) treated MCF-7 cells.	Methanol	102-106	cytochrome c, somatic	Homo sapiens	38-50
22056335-7	2012	Increased levels of Bax and cytosolic cytochrome C and decreased levels of Bcl2 were also observed in MeOH:water (80:20) treated MCF-7 cells.	Methanol	102-106	BCL2 apoptosis regulator	Homo sapiens	75-79
22082800-5	2012	These Pt/CNF nanocomposites exhibited higher electrocatalytic activity toward methanol oxidation reaction compared with commercial E-TEK Pt/C catalyst.	Methanol	78-86	NPHS1 adhesion molecule, nephrin	Homo sapiens	9-12
22224493-10	2012	The protection of microglial cells by acai pulp extracts, particularly that of MEOH, ETOH, and ACE fractions, was also accompanied by a significant concentration-dependent reduction in cyclooxygenase-2 (COX-2), p38 mitogen-activated protein kinase (p38-MAPK), tumor necrosis factor-alpha (TNFalpha), and nuclear factor kappaB (NF-kappaB).	Methanol	79-83	prostaglandin-endoperoxide synthase 2	Mus musculus	203-208
22082800-5	2012	These Pt/CNF nanocomposites exhibited higher electrocatalytic activity toward methanol oxidation reaction compared with commercial E-TEK Pt/C catalyst.	Methanol	78-86	TEK receptor tyrosine kinase	Homo sapiens	133-136
21993858-0	2012	Methanol extract of Hydroclathrus clathratus suppresses matrix metalloproteinase-9             in T24 bladder carcinoma cells by suppressing the NF-kappaB and MAPK pathways.	Methanol	0-8	matrix metallopeptidase 9	Homo sapiens	56-82
22220982-1	2012	The self-assembly of Co(O(2)CPh)(2) with a 2,3-dihydroxyquinoxaline (H(2)dhq) linker has revealed a new two-dimensional cluster-based compound, [Co(4)(OMe)(2)(O(2)CPh)(2)(dhq)(2)(MeOH)(2)](n), which shows spin-canted magnetization and a definite magnetic hysteresis loop.	Methanol	179-183	carboxypeptidase E	Homo sapiens	28-31
22170388-4	2012	Methanol solvate 1 shows obvious frequency dependence of out-of-phase alternating-current magnetic susceptibility below 2 K and a magnetization hysteresis loop with a coercive field of 400 Oe at 0.5 K. It is the first example of spin-canted supramolecular single-chain magnet due to weak pi-pi stacking interaction.	Methanol	0-8	spindlin 1	Homo sapiens	229-233
22122231-1	2012	For the last step of rhodium-catalyzed methanol carbonylation, high-pressure NMR, and kinetic and experimental data supported by density functional theory calculations are consistent with substitution of I(-) by an AcO(-) ligand on the [RhI(3)(COCH(3))(CO)(2)](-) species followed by reductive elimination of acetic anhydride, which immediately reacts with water to afford acetic acid.	Methanol	39-47	cochlin	Homo sapiens	244-248
22313768-3	2012	Disruption of the MSN5 gene in this yeast caused retardation of growth on formaldehyde-generating growth substrates such as methanol and methylamine, but the expression levels of the methanol-metabolizing enzymes did not fall.	Methanol	124-132	karyopherin MSN5	Saccharomyces cerevisiae S288C	18-22
22313768-3	2012	Disruption of the MSN5 gene in this yeast caused retardation of growth on formaldehyde-generating growth substrates such as methanol and methylamine, but the expression levels of the methanol-metabolizing enzymes did not fall.	Methanol	183-191	karyopherin MSN5	Saccharomyces cerevisiae S288C	18-22
22203864-8	2012	Hepatic antioxidant enzymes, namely, SOD, CAT, and GSH-Px, were significantly decreased in methanol-treated animals.	Methanol	91-99	catalase	Rattus norvegicus	42-45
22991570-7	2012	These results were indicated that anti-inflammatory mechanism of CR(MeOH) may be due to declined levels of NO and MDA in the edema paw through increasing the activities of SOD, GPx, and GRd in the liver.	Methanol	68-72	peroxiredoxin 6 pseudogene 2	Mus musculus	177-180
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	interleukin 1 beta	Mus musculus	38-46
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	interleukin 6	Mus musculus	48-52
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	54-62
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	tumor necrosis factor	Mus musculus	64-73
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	cytochrome c oxidase II, mitochondrial	Mus musculus	75-80
22991570-8	2012	Additionally, CR(MeOH) also decreased IL-1beta, IL-6, NFkappaB, TNF-alpha, COX-2, and iNOS levels.	Methanol	17-21	nitric oxide synthase 2, inducible	Mus musculus	86-90
23320038-0	2012	Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.	Methanol	29-37	adhesion G protein-coupled receptor L1	Homo sapiens	100-103
22919411-2	2012	The 70% methanol extract showed comparatively higher inhibition of thymus and activation-regulated chemokine (TARC/CCL17) in HaCaT cells, therefore this extract was further partitioned with n-hexane, chloroform, ethyl acetate, butanol, and water.	Methanol	8-16	C-C motif chemokine ligand 17	Homo sapiens	110-114
22919411-2	2012	The 70% methanol extract showed comparatively higher inhibition of thymus and activation-regulated chemokine (TARC/CCL17) in HaCaT cells, therefore this extract was further partitioned with n-hexane, chloroform, ethyl acetate, butanol, and water.	Methanol	8-16	C-C motif chemokine ligand 17	Homo sapiens	115-120
22563443-10	2012	Subsequently, we showed that the methanol generated by the pectin/PME complex in the gastrointestinal tract of mice induces the up- and downregulation of brain MRG mRNA.	Methanol	33-41	fatty acid binding protein 7, brain	Mus musculus	160-163
22844269-6	2012	While the ether and methanol extracts showed greater inhibitory activities against both rat lens and human ALR2, the water and ethanol extracts showed moderate inhibitory activities.	Methanol	20-28	aldo-keto reductase family 1 member B	Homo sapiens	107-111
22968696-0	2012	A non-syn-gas catalytic route to methanol production.	Methanol	33-41	synemin	Homo sapiens	6-9
22968696-2	2012	At present, methanol is manufactured from natural gas via the indirect syn-gas route.	Methanol	12-20	synemin	Homo sapiens	71-74
23118913-6	2012	We demonstrate the utility of FREQ-Seq by determining the order and dynamics of beneficial alleles that arose as a microbial population, founded with an engineered strain of Methylobacterium, evolved to grow on methanol.	Methanol	211-219	neuronal calcium sensor 1	Homo sapiens	30-34
23018855-1	2012	The methanol extract of Morus australis (shimaguwa) acts as a whitening agent due to the inhibition of tyrosinase activity.	Methanol	4-12	tyrosinase	Mus musculus	103-113
21756194-2	2012	A simple and accurate high-performance liquid chromatographic (HPLC) method was successfully developed for simultaneous determination of LGL and AGL in rat plasma after the plasma protein was precipitated with methanol.	Methanol	210-218	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Rattus norvegicus	145-148
22563443-12	2012	We showed that mice prefer the odor of methanol to other plant volatiles and that methanol changed MRG mRNA accumulation in the mouse brain.We hypothesize that the methanol emitted by wounded plants may have a role in plant-animal signaling.	Methanol	82-90	fatty acid binding protein 7, brain	Mus musculus	99-102
22563443-12	2012	We showed that mice prefer the odor of methanol to other plant volatiles and that methanol changed MRG mRNA accumulation in the mouse brain.We hypothesize that the methanol emitted by wounded plants may have a role in plant-animal signaling.	Methanol	82-90	fatty acid binding protein 7, brain	Mus musculus	99-102
21422078-3	2011	Treatment of rats with methanol significantly increased lipid peroxidation (LPO) level and decreased the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in erythrocytes.	Methanol	23-31	catalase	Rattus norvegicus	147-155
23961169-1	2012	This study was initiated to screen the antioxidant activities, tyrosinase inhibitory effects on the fruiting bodies of Pleurotus ferulae extracted with acetone, methanol and hot water.	Methanol	161-169	tyrosinase	Homo sapiens	63-73
22111710-3	2011	A four order-of-magnitude of activation for the methanol substitution is induced as manifested by the second order rate constants with (N,N"-Bid) &lt; (N,O-Bid) &lt; (O,O"-Bid).	Methanol	48-56	BH3 interacting domain death agonist	Homo sapiens	141-144
22111710-3	2011	A four order-of-magnitude of activation for the methanol substitution is induced as manifested by the second order rate constants with (N,N"-Bid) &lt; (N,O-Bid) &lt; (O,O"-Bid).	Methanol	48-56	BH3 interacting domain death agonist	Homo sapiens	156-159
22111710-3	2011	A four order-of-magnitude of activation for the methanol substitution is induced as manifested by the second order rate constants with (N,N"-Bid) &lt; (N,O-Bid) &lt; (O,O"-Bid).	Methanol	48-56	BH3 interacting domain death agonist	Homo sapiens	156-159
21907269-1	2011	Assessment of the UV protecting potential of an aqueous methanol leaf extract of Harpephyllum caffrum proved that it possesses a distinct radical scavenging effect and inhibits the production of the proinflammatory cytokine IL-6 by human keratinocytes (HaCaT cells) following UV radiation.	Methanol	56-64	interleukin 6	Homo sapiens	224-228
21422078-3	2011	Treatment of rats with methanol significantly increased lipid peroxidation (LPO) level and decreased the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in erythrocytes.	Methanol	23-31	catalase	Rattus norvegicus	157-160
21340526-8	2011	However, acid methanol extracts of potato shoots or roots carrying the MYB10 gene contained up to four times higher anthocyanin content than control plants.	Methanol	14-22	transcription factor MYB113-like	Malus domestica	71-76
21975542-1	2011	The mass ORR activity of CO heat-treated PdCoAu/C catalysts, compared to Pd/C, is enhanced approximately 6-fold, and even 25-fold in a methanol containing environment due to the formation of delicate PdCo and PdAu alloys enriched in the core and PdAu alloy species enriched on the shell structure.	Methanol	135-143	phosducin	Homo sapiens	73-77
22433878-6	2011	Our results suggest that recombinant SAG1/2 were best expressed at 30oC, pH 6 and   1% methanol as the carbon source by X33 Pichia cells.	Methanol	87-95	Sag1p	Saccharomyces cerevisiae S288C	37-43
21873495-1	2011	In Gram-negative methylotrophic bacteria, the first step in methylotrophic growth is the oxidation of methanol to formaldehyde in the periplasm by methanol dehydrogenase.	Methanol	102-110	MEXAM1_RS21720	Methylobacterium extorquens AM1	156-169
22022887-3	2011	Deboronation of the products by treatment with triflic acid or iodine and then methanol opens a route to C4/C5 functionalized imidazolium salts and imidazol-2-ylidenes.	Methanol	79-87	complement C4A (Rodgers blood group)	Homo sapiens	105-110
22219946-1	2011	The title compound, C(35)H(35)NO(2) CH(4)O, was obtained by the reaction of rac-2-amino-2-hy-droxy-1,1-binaphthyl and 3,5-di-tert-butyl-2-hy-droxy-benzaldehyde in absolute methanol.	Methanol	172-180	Rac family small GTPase 2	Homo sapiens	76-81
21825116-1	2011	In this study, we report the effect of dimethyl sulfoxide (DMSO), acetonitrile, and methanol on the CYP1A2-mediated metabolism of phenacetin in human liver microsomes.	Methanol	84-92	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	100-106
21861531-9	2011	Additionally, CD spectroscopy studies of the Ns1npe homo-oligomers in acetonitrile and methanol revealed a striking length-dependent increase in ellipticity per amide.	Methanol	87-95	influenza virus NS1A binding protein	Homo sapiens	45-48
21982417-5	2011	It is confirmed that the prepared Au@PtAg alloy nanorods/graphene hybrid composites own good catalytic function for methanol electro-oxidation by cyclic voltammograms measurements, and exhibited higher catalytic activity and more stability than pure Au@Pt nanorods and Au@AgPt alloy nanorods.	Methanol	116-124	rhomboid domain containing 3	Homo sapiens	37-41
21701716-5	2011	Melittin is haemolytic and has been shown to form an alpha-helical tetrameric structure by X-ray crystallography [M. Gribskov et al., The RCSB Protein Data Bank, 1990] and to be helical in high concentrations of methanol.	Methanol	212-220	melittin	Apis mellifera	0-8
21862322-3	2011	Arenesulfonic acid-functionalized SBA-15 silica catalyst has provided yields to FAME close to 80% in the simultaneous esterification-transesterification of the different feedstocks, regardless of their nature and properties, using methanol under the following reaction conditions: 160  C, 2 h, methanol to oil molar ratio of 30, 8 wt.% catalyst loading, and 2000 rpm stirring rate.	Methanol	231-239	benign adult familial myoclonic epilepsy 1	Homo sapiens	80-84
22586241-6	2011	In this study, dilution of the tap water sample by adding 4% MeOH (v/v) was observed to be adequate to compensate for the signal suppression.	Methanol	61-65	nuclear RNA export factor 1	Homo sapiens	31-34
21838258-6	2011	Based on the MP2/CBS results, the most stable C(6)H(6)(MeOH)(3) cluster is characterized by a hydrogen bonded MeOH trimer chain interacting with benzene via pi   H-O and O   H-C(benzene) hydrogen bonds.	Methanol	55-59	tryptase pseudogene 1	Homo sapiens	13-16
21838258-6	2011	Based on the MP2/CBS results, the most stable C(6)H(6)(MeOH)(3) cluster is characterized by a hydrogen bonded MeOH trimer chain interacting with benzene via pi   H-O and O   H-C(benzene) hydrogen bonds.	Methanol	110-114	tryptase pseudogene 1	Homo sapiens	13-16
21969616-9	2011	The second technique for methanol-acetone fixation described here has proved to be particularly suitable for gamma-tubulin and centrosomin immunostaining.	Methanol	25-33	centrosomin	Drosophila melanogaster	127-138
21838258-2	2011	Benzene-methanol (MeOH) clusters containing up to six methanol molecules have been calculated by ab initio [MP2/6-311++G(d,p)//MP2/6-31+G(d,p) + BSSE correction] method.	Methanol	8-16	tryptase pseudogene 1	Homo sapiens	127-130
21838258-2	2011	Benzene-methanol (MeOH) clusters containing up to six methanol molecules have been calculated by ab initio [MP2/6-311++G(d,p)//MP2/6-31+G(d,p) + BSSE correction] method.	Methanol	18-22	tryptase pseudogene 1	Homo sapiens	108-111
21838258-2	2011	Benzene-methanol (MeOH) clusters containing up to six methanol molecules have been calculated by ab initio [MP2/6-311++G(d,p)//MP2/6-31+G(d,p) + BSSE correction] method.	Methanol	18-22	tryptase pseudogene 1	Homo sapiens	127-130
21792440-5	2011	Furthermore, the reduction of Os(VIII) with MeOH or EtOH is first order with respect to the aliphatic alcohol concentration.	Methanol	44-48	cytochrome c oxidase subunit 8A	Homo sapiens	33-37
21796325-4	2011	The interaction of Co(II), Ni(II) and Cu(II) with the unsymmetric macrocycle series has been investigated by potentiometric (pH) titration in 95% methanol; X-ray structures of two nickel and three copper complexes of these ligands, each exhibiting 1:1 (M:L) ratios, have been obtained.	Methanol	146-154	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	19-25
21830821-2	2011	Over the range of solution compositions studied, from 0:100 to 100:0 methanol:water and 0:100 to 90:10 dioxane:water, evidence for 10 independent populations of bradykinin structures in solution is found.	Methanol	69-77	kininogen 1	Homo sapiens	161-171
21443496-1	2011	In the biomimetic design two hydrophobic pentapetides Boc-Ile-Aib-Leu-Phe-Ala-OMe (I) and Boc-Gly-Ile-Aib-Leu-Phe-OMe (II) (Aib: alpha-aminoisobutyric acid) containing one Aib each are found to undergo solvent assisted self-assembly in methanol/water to form vesicular structures, which can be disrupted by simple addition of acid.	Methanol	236-244	ANIB1	Homo sapiens	102-105
21780285-2	2011	First, by means of ACE, the apparent binding constant of LiR(+) complex (K LiR +) in methanol was determined from the dependence of the effective electrophoretic mobilities of LiR(+) complex on the concentration of lithium ions in the 25 mM Tris/50 mM chloroacetate background electrolyte (BGE) using non-linear regression analysis.	Methanol	85-93	CD300c molecule	Homo sapiens	57-60
21780285-2	2011	First, by means of ACE, the apparent binding constant of LiR(+) complex (K LiR +) in methanol was determined from the dependence of the effective electrophoretic mobilities of LiR(+) complex on the concentration of lithium ions in the 25 mM Tris/50 mM chloroacetate background electrolyte (BGE) using non-linear regression analysis.	Methanol	85-93	CD300c molecule	Homo sapiens	75-78
21780285-2	2011	First, by means of ACE, the apparent binding constant of LiR(+) complex (K LiR +) in methanol was determined from the dependence of the effective electrophoretic mobilities of LiR(+) complex on the concentration of lithium ions in the 25 mM Tris/50 mM chloroacetate background electrolyte (BGE) using non-linear regression analysis.	Methanol	85-93	CD300c molecule	Homo sapiens	75-78
21592134-8	2011	Foliar PME activity was related to MeOH flux, but unexplained variance suggested PME activity could not predict emissions.	Methanol	35-39	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	7-10
21592134-9	2011	The data show that MeOH production and emission are complex and cannot be predicted using PME activity alone.	Methanol	19-23	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	90-93
21554119-3	2011	The activity of P2X(7) was studied with a dye uptake assay and with the whole-cell patch clamp technique in mouse peritoneal macrophages treated with methanol extract of R. longifolia leaves and fractions.	Methanol	150-158	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	16-22
21547923-4	2011	RESULTS: The methanol extracts from three edible Vietnamese-grown plants, Tram, Voi and Gac, tested with the DPPH assay showed antioxidant activities of 91.7 +- 0.4, 63.4 +- 0.7 and 3.7 +- 0.1% respectively.	Methanol	13-21	translocation associated membrane protein 1	Homo sapiens	74-78
21443496-1	2011	In the biomimetic design two hydrophobic pentapetides Boc-Ile-Aib-Leu-Phe-Ala-OMe (I) and Boc-Gly-Ile-Aib-Leu-Phe-OMe (II) (Aib: alpha-aminoisobutyric acid) containing one Aib each are found to undergo solvent assisted self-assembly in methanol/water to form vesicular structures, which can be disrupted by simple addition of acid.	Methanol	236-244	ANIB1	Homo sapiens	102-105
21443496-1	2011	In the biomimetic design two hydrophobic pentapetides Boc-Ile-Aib-Leu-Phe-Ala-OMe (I) and Boc-Gly-Ile-Aib-Leu-Phe-OMe (II) (Aib: alpha-aminoisobutyric acid) containing one Aib each are found to undergo solvent assisted self-assembly in methanol/water to form vesicular structures, which can be disrupted by simple addition of acid.	Methanol	236-244	ANIB1	Homo sapiens	102-105
21544291-3	2011	The structures and vibrational spectra of dimeric complexes of methanol with H(2)O, HF, HCN, HNC, HOF, HNO, and HSN are investigated at the MP2/6-311++G(2d,2p) approach.	Methanol	63-71	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	88-91
22276430-7	2011	Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions.	Methanol	119-127	glutamate--cysteine ligase	Saccharomyces cerevisiae S288C	25-29
22276430-7	2011	Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions.	Methanol	119-127	glutamate--cysteine ligase	Saccharomyces cerevisiae S288C	39-43
22276430-7	2011	Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions.	Methanol	119-127	uroporphyrinogen-III C-methyltransferase	Saccharomyces cerevisiae S288C	44-48
22233084-4	2011	GA1, GA3 and GA4 were eluted with cold 80% methanol aqueous solution.	Methanol	43-51	Terpenoid cyclases/Protein prenyltransferases superfamily protein	Arabidopsis thaliana	0-3
22233084-4	2011	GA1, GA3 and GA4 were eluted with cold 80% methanol aqueous solution.	Methanol	43-51	gibberellin 3-oxidase 1	Arabidopsis thaliana	13-16
21544291-3	2011	The structures and vibrational spectra of dimeric complexes of methanol with H(2)O, HF, HCN, HNC, HOF, HNO, and HSN are investigated at the MP2/6-311++G(2d,2p) approach.	Methanol	63-71	tryptase pseudogene 1	Homo sapiens	140-143
21819779-0	2011	Solvent interactions in methanol/N, N-dimethylamide binary systems studied by Fourier transform infrared-attenuated total reflection (FT-IR/ATR) and two-dimensional correlation spectroscopy (2D-COS).	Methanol	24-32	ATR serine/threonine kinase	Homo sapiens	134-143
21397238-3	2011	Using Chiralpak AD-H and eluting with pure methanol (without acidic or basic additives) relatively short retention times, high enantioselectivity and good resolution (alpha=1.49, R(s)=3.48) were observed.	Methanol	43-51	alcohol dehydrogenase 1A (class I), alpha polypeptide	Homo sapiens	16-20
21819779-1	2011	The interaction of N,N-dimethyl formamide (DMF) and N,N-dimethyl acetamide (DMA) with methanol in solution mixtures was studied using Fourier transform infrared-attenuated total reflection (FT-IR/ATR) spectroscopy.	Methanol	86-94	ATR serine/threonine kinase	Homo sapiens	190-199
21565216-5	2011	We found that the conformation of SF contained in PCL/SF composite nanofibers was transformed from random coil to beta-sheet when treated with methanol, leading to improved crystallinity and tensile strength of nanofibrous scaffolds.	Methanol	143-151	PHD finger protein 1	Homo sapiens	50-53
21718017-3	2011	Uranium atoms react spontaneously with methanol on annealing to form the U(II) insertion product CH(3)OUH, which has a quintet ground state with strong C-O and U-H stretching vibrations.	Methanol	39-47	urotensin 2	Homo sapiens	73-77
21910345-3	2011	The recombinant PAP was subcloned into the expression vector pPICZaA and expressed in Pichia pastoris GSI15 after methanol induction.	Methanol	114-122	regenerating family member 3 alpha	Homo sapiens	16-19
21472730-5	2011	The crystal forms of SA and SSU.MeOH were determined to be triclinic, (Pi), and monoclinic, (P2(1) /n), respectively.	Methanol	32-36	cyclin dependent kinase inhibitor 1A	Homo sapiens	93-98
21721540-3	2011	The MOF selectively interacts with hydroxylic guests in contrast to aprotic hydrogen-bonding guests and shows a sorption selectivity for protic H(2)O, MeOH, and EtOH guests.	Methanol	151-155	lysine acetyltransferase 8	Homo sapiens	4-7
21836833-1	2011	The title mononuclear cobalt(III) complex, [Co(C(14)H(19)N(2)O(2))(C(8)H(7)O(2))(NCS)], was obtained by the reaction of 2-acetyl-phenol, 2-(morpholin-4-yl)ethyl-amine, ammonium thio-cyan-ate and cobalt nitrate in methanol.	Methanol	213-221	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	29-32
21648459-2	2011	By significantly decreasing the rotation rate of the quinoline-carbinol bond, the relatively bulky CF(3) group enables the NMR signals of the syn and anti conformers to be differentiated at room temperature.	Methanol	63-71	synemin	Homo sapiens	142-145
21639107-4	2011	In addition, dinuclear and trinuclear mu-hydroxo Co(III) complexes have been obtained in the presence of phosphate anions and absence of methanol, respectively, suggesting that an additional bridging ligand is needed to stabilize the Co(III)bis(mu-hydroxo)Co(III) fragment.	Methanol	137-145	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	49-56
21639107-4	2011	In addition, dinuclear and trinuclear mu-hydroxo Co(III) complexes have been obtained in the presence of phosphate anions and absence of methanol, respectively, suggesting that an additional bridging ligand is needed to stabilize the Co(III)bis(mu-hydroxo)Co(III) fragment.	Methanol	137-145	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	52-55
21756092-4	2011	CONCLUSION: The new approach (which utilizes a mixture of methanol and acetonitrile as the organic mobile phase on a 2.1 x 20 mm C18 column) minimized phospholipids-related matrix effects in the analysis of plasma samples prepared by protein precipitation and is suitable for high-throughput bioanalysis in drug discovery.	Methanol	58-66	Bardet-Biedl syndrome 9	Homo sapiens	129-132
21938950-4	2011	The results presented here show that the methanol extract of Cotinus coggygria in a concentration of 5% and artificial chemical agent ethyl methanesulfonate EMS (0.75 ppm) induce recessive lethal mutations on X-chromosome on Drosophila melanogaster in all broods (I, II and III).	Methanol	41-49	l(2)46Cc	Drosophila melanogaster	263-277
23408781-3	2011	The amount of AAT protein in medium was measured as 60 mg/l 72 hr after induction with methanol.	Methanol	87-95	serpin family A member 1	Homo sapiens	14-17
21699742-0	2011	Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat.	Methanol	28-36	C-C motif chemokine ligand 4	Rattus norvegicus	72-76
21246637-6	2011	The present study showed that the methanol extract of E. rutaecarpa decreased the TPA-induced AP-1 transactivation in Chang/AP-1 cells, with an EC50 value of 24.72 mug/mL.	Methanol	34-42	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	94-98
21246637-6	2011	The present study showed that the methanol extract of E. rutaecarpa decreased the TPA-induced AP-1 transactivation in Chang/AP-1 cells, with an EC50 value of 24.72 mug/mL.	Methanol	34-42	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	124-128
21618631-0	2011	Frequency-domain Fourier-transform terahertz spectroscopy of the single-molecule magnet (NEt4)[Mn2(5-Brsalen)2(MeOH)2Cr(CN)6].	Methanol	111-115	tetraspanin 5	Homo sapiens	89-93
21507333-3	2011	MT-2 cells were fixed with 100% methanol on round glass lamina or cleaved mica and dried under UV light and laminar flow.	Methanol	32-40	metallothionein 2A	Homo sapiens	0-4
21539457-4	2011	The H-protein cDNA was subsequently cloned with a hexahistidine affinity tag in the Pichia pastoris plasmid vector pPICZalphaA and recombined into the yeast genome downstream of the alcohol oxidase promoter for methanol-induced expression.	Methanol	211-219	myosin binding protein H	Homo sapiens	4-13
21557566-3	2011	The dehydrated framework, {(H(2)PIP)(0.5)[VO(CEP)]} (1") shows selective and gated adsorption behavior with H(2)O but not with methanol and ethanol.	Methanol	127-135	prolactin induced protein	Homo sapiens	32-35
21690056-3	2011	Commercial samples of Chaihu were obtained from 10 drug stores in Guangzhou, and SSa contents in the methanol extracts of these samples were determined using the ELISA system.	Methanol	101-109	tripartite motif containing 21	Homo sapiens	81-84
21690056-5	2011	In the 10 commercial Chaihu samples, SSa contents in the methanol extract determined by this method ranged from 0.32 microg/mg to 6.87 microg/mg, and 3 samples showed a SSa content lower than the minimum requirement documented in the Chinese Pharmacopeia.	Methanol	57-65	tripartite motif containing 21	Homo sapiens	37-40
21629182-2	2011	The crude methanol and fractionated extracts (hexane and ethyl acetate) displayed good cytotoxic effects against MCF-7, KB, A549, Ca Ski and HT-29 cell lines, but exerted no damage on the MRC-5 line.	Methanol	10-18	SKI proto-oncogene	Homo sapiens	133-136
21530777-7	2011	SPE analyses of a mixture of BER and PAL and the methanol extract from the cortices of Phellodendron wilsonii showed that AD-10 had more efficiency, and higher specificity and selectivity for SPE in the concentration and determination of BER and its extraction from natural products.	Methanol	49-57	AD10	Homo sapiens	122-127
20979021-3	2011	The MeOH extract inhibited the production of phorbol-12-myristate-13-acetate-induced inflammatory cytokines such as tumor necrosis factor (TNF)-alpha in cultured THP-1 cells, and also restrained the intracellular synthesis of melanin in murine melanoma B16F1 cells.	Methanol	4-8	tumor necrosis factor	Homo sapiens	116-149
21503326-1	2011	Methanol (MeOH) oxidation reaction (MOR) at Pt electrodes under potentiostatic conditions has been investigated by electrochemical in situ FTIR spectroscopy (FTIRS) in attenuated-total-reflection configuration under controlled flow conditions in 0.1 M HClO(4) with 2 M MeOH, where the mass transport effects are largely eliminated using a flow cell.	Methanol	0-8	opioid receptor mu 1	Homo sapiens	36-39
21503326-1	2011	Methanol (MeOH) oxidation reaction (MOR) at Pt electrodes under potentiostatic conditions has been investigated by electrochemical in situ FTIR spectroscopy (FTIRS) in attenuated-total-reflection configuration under controlled flow conditions in 0.1 M HClO(4) with 2 M MeOH, where the mass transport effects are largely eliminated using a flow cell.	Methanol	10-14	opioid receptor mu 1	Homo sapiens	36-39
21503326-1	2011	Methanol (MeOH) oxidation reaction (MOR) at Pt electrodes under potentiostatic conditions has been investigated by electrochemical in situ FTIR spectroscopy (FTIRS) in attenuated-total-reflection configuration under controlled flow conditions in 0.1 M HClO(4) with 2 M MeOH, where the mass transport effects are largely eliminated using a flow cell.	Methanol	269-273	opioid receptor mu 1	Homo sapiens	36-39
21423932-1	2011	The diblock copolymer, BP26, assembled into polymeric vesicles with double layers that formed a hydrophobic crystalline interior and a hydrophilic amorphous exterior in methanol, a selective solvent for the PEGT block.	Methanol	169-177	BP26	Homo sapiens	23-27
21395555-6	2011	Treatment of these cells with an organic solvent such as 100% methanol, which selectively removes glycolipids from plasma membrane, abolished the immunoreactivity with those antibodies, indicating that the reactivity was due to GD2 and GD3, but not to GD2-/GD3-like glycoproteins or proteoglycans.	Methanol	62-70	GRDX	Homo sapiens	236-239
21495757-10	2011	Anharmonic vibrational wavenumbers predicted for the methanol open-chain dimer and the cyclic trimer with the B3LYP/VPT2/ANO1 level of theory are consistent with experimental results.	Methanol	53-61	anoctamin 1	Homo sapiens	121-125
21340057-4	2011	The presence of hydrogen-bond-mediated intermolecular interactions, that involve the methanol molecules, yields dimers of dinuclear units for 1 2MeOH, and infinite zig-zag chains for 2 2MeOH.	Methanol	85-93	alpha-2-glycoprotein 1, zinc-binding	Homo sapiens	168-171
21395555-6	2011	Treatment of these cells with an organic solvent such as 100% methanol, which selectively removes glycolipids from plasma membrane, abolished the immunoreactivity with those antibodies, indicating that the reactivity was due to GD2 and GD3, but not to GD2-/GD3-like glycoproteins or proteoglycans.	Methanol	62-70	GRDX	Homo sapiens	257-260
21155714-5	2011	The data suggest that CCZ1, MON1 and YPT7 genes are involved in degradation of both small oleate-induced and large methanol-induced peroxisomes.	Methanol	115-123	Ccz1p	Saccharomyces cerevisiae S288C	22-26
21155714-5	2011	The data suggest that CCZ1, MON1 and YPT7 genes are involved in degradation of both small oleate-induced and large methanol-induced peroxisomes.	Methanol	115-123	Mon1p	Saccharomyces cerevisiae S288C	28-32
21155714-5	2011	The data suggest that CCZ1, MON1 and YPT7 genes are involved in degradation of both small oleate-induced and large methanol-induced peroxisomes.	Methanol	115-123	Rab family GTPase YPT7	Saccharomyces cerevisiae S288C	37-41
20963445-5	2011	The recombinant AChE protein was then expressed in P. pastoris strain GS115 by methanol induction.	Methanol	79-87	neuroligin-4, Y-linked	Musca domestica	16-20
21634244-5	2011	Treatment of mice with 70% methanol extract of each plant extract reduced significantly ALT, AST &amp; GGT elevation.	Methanol	27-35	glutamic pyruvic transaminase, soluble	Mus musculus	88-91
21634244-5	2011	Treatment of mice with 70% methanol extract of each plant extract reduced significantly ALT, AST &amp; GGT elevation.	Methanol	27-35	gamma-glutamyltransferase 1	Mus musculus	103-106
21295602-0	2011	Altered methanol embryopathies in embryo culture with mutant catalase-deficient mice and transgenic mice expressing human catalase.	Methanol	8-16	catalase	Homo sapiens	61-69
21295602-3	2011	This hypothesis was investigated in whole embryo culture to remove confounding maternal factors, including metabolism of MeOH by maternal catalase.	Methanol	121-125	catalase	Mus musculus	138-146
21210672-2	2011	At room temperature, the native structure of cytochrome c is maintained in relatively high ionic liquid concentrations (50-70% AAF/water or AAF/phosphate buffer pH 7.0) in contrast with denaturation of cytochrome c in similar solutions of methanol or acetonitrile with water or buffer cosolvents.	Methanol	239-247	cytochrome c, somatic	Homo sapiens	45-57
21329526-8	2011	The in vitro cytotoxicity assay on human hepatocarcinoma cell line (Huh-7) revealed that the methanol extract of E. autumnalis had the strongest cytotoxicity with IC(50) of 7.8 mug/ml.	Methanol	93-101	MIR7-3 host gene	Homo sapiens	68-73
21319242-4	2011	The molecular structure of [PdCl(2)(1H OCH(3))] was determined crystallographically and revealed that the reaction with methanol proceeds selectively by syn addition and exclusively to one of the P=C double bonds.	Methanol	120-128	synemin	Homo sapiens	153-156
21210672-4	2011	About one-third of the enzyme activity of cytochrome c in 80% AAF-20% water can be maintained as compared with phosphate buffer, and this is greater than the activities measured in corresponding methanol and acetonitrile aqueous solutions.	Methanol	195-203	cytochrome c, somatic	Homo sapiens	42-54
20959418-2	2011	In methanol, phospholipase A2 preferentially hydrolyzes CL to MLCL.	Methanol	3-11	phospholipase A2 group IB	Homo sapiens	13-29
20959418-5	2011	Only the sn-2 position of CL was hydrolyzed by phospholipase A2 in methanol.	Methanol	67-75	phospholipase A2 group IB	Homo sapiens	47-63
21916258-8	2011	In contrast, only dichloromethane and methanol extracts enhanced CYP2B activity.	Methanol	38-46	cytochrome P450, family 2, subfamily b, polypeptide 10	Mus musculus	65-70
20868645-7	2011	Lung samples of control and LVS-inoculated mice were quickly extracted with a methanol/chloroform solution, and the crude extract was directly analyzed by DESI-MS, with a total turnaround time of less than 10 min/sample.	Methanol	78-86	lacking vigorous sperm	Mus musculus	28-31
21042611-2	2011	The Coulomb contribution for the interaction potential was damped by a factor eta varied from 1 to 0.49 for water and 1 to 0.15 for methanol.	Methanol	132-140	endothelin receptor type A	Homo sapiens	78-81
21915205-3	2011	The reaction of 17 with sodium methoxide generated tribromodihydroanthracene-1,4-diol 27, whose oxidation with PCC gave 2,9,10-tribromoanthracene-1,4-dione (28).	Methanol	24-40	crystallin gamma D	Homo sapiens	111-114
20933271-9	2011	Degrease with methanol/chloroform dramatically reduced the contents of VEGF, b-FGF, TGF-beta, and TNF-alpha within SISii, but further treatment could not significantly reduced the contents of growth factors.	Methanol	14-22	vascular endothelial growth factor A	Rattus norvegicus	71-75
20933271-9	2011	Degrease with methanol/chloroform dramatically reduced the contents of VEGF, b-FGF, TGF-beta, and TNF-alpha within SISii, but further treatment could not significantly reduced the contents of growth factors.	Methanol	14-22	tumor necrosis factor	Rattus norvegicus	98-107
21567328-5	2011	The filtered extract is purified by immunoaffinity column and FB(1) and FB(2) are eluted with methanol.	Methanol	94-102	Protein DEHYDRATION-INDUCED 19 homolog 5	Zea mays	72-77
21785639-7	2011	The IC50s of methanol extract, hexane fraction and curdione to oxidized nifedipine formation were 21, 14 and 3.9 mug ml(-1) (16.9 muM), respectively.	Methanol	13-21	latexin	Homo sapiens	130-133
20131957-1	2010	Our previous study has demonstrated that the methanol extract of Hyul-Tong-Ryung (HM) specifically suppresses the phorbol 12-myristate 13-acetate (PMA)-induced matrix metalloproteinase-9 (MMP-9) production through the inhibition of MMP-9 mRNA expression in MCF-7 human breast carcinoma cells.	Methanol	45-53	matrix metallopeptidase 9	Homo sapiens	188-193
21077663-5	2010	Photocatalytic activities of SAN for the evolution of H(2) and O(2) respectively from aqueous solutions of methanol and AgF decreased with increasing the calcination time, that is, with increasing the fraction of the ordered phase.	Methanol	107-115	N-alpha-acetyltransferase 50, NatE catalytic subunit	Homo sapiens	29-32
20709172-1	2011	A gene encoding cellobiose dehydrogenase (CDH) from Neurospora crassa strain FGSC 2489 has been cloned and expressed in the heterologous host Pichia pastoris, under the control of the AOX1 methanol inducible promoter.	Methanol	189-197	cdh-2	Neurospora crassa OR74A	16-40
20709172-1	2011	A gene encoding cellobiose dehydrogenase (CDH) from Neurospora crassa strain FGSC 2489 has been cloned and expressed in the heterologous host Pichia pastoris, under the control of the AOX1 methanol inducible promoter.	Methanol	189-197	cdh-2	Neurospora crassa OR74A	42-45
21090592-4	2010	The ligands dpk OH(-) and dpk CH(3)O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	110-118	TAO kinase 3	Homo sapiens	12-15
21090592-4	2010	The ligands dpk OH(-) and dpk CH(3)O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	110-118	TAO kinase 3	Homo sapiens	26-29
21090592-4	2010	The ligands dpk OH(-) and dpk CH(3)O(-) result from solvolysis and ulterior deprotonation of dpk in water and methanol, respectively.	Methanol	110-118	TAO kinase 3	Homo sapiens	26-29
20884002-1	2010	The structure of the octadecyl (C18) chain layer attached to a silica surface in the presence of binary solvents (acetonitrile/water; methanol/water) was investigated by electron paramagnetic resonance (EPR) and reverse-phase high-performance liquid chromatography (RP-HPLC), using 4-hydroxy-2,2,6,6 tetramethylpiperidine-N-oxyl (Tempol) to mimic the behavior of pollutants with medium-low polarity.	Methanol	134-142	Bardet-Biedl syndrome 9	Homo sapiens	32-35
20945314-8	2010	When the supporting solutions contained active fuel molecules in addition to the intermetallic nanoparticles (formic acid for PtBi, formic acid and methanol for PtPb), kinetic stabilization effects were observed for E(ulp)=+0.80 V, in a way similar to the response of the bulk materials.	Methanol	148-156	protein tyrosine phosphatase receptor type B	Homo sapiens	161-165
20131957-1	2010	Our previous study has demonstrated that the methanol extract of Hyul-Tong-Ryung (HM) specifically suppresses the phorbol 12-myristate 13-acetate (PMA)-induced matrix metalloproteinase-9 (MMP-9) production through the inhibition of MMP-9 mRNA expression in MCF-7 human breast carcinoma cells.	Methanol	45-53	matrix metallopeptidase 9	Homo sapiens	232-237
20229016-7	2010	The expression of recombinant rat Ang2 (rrAng2) was induced by methanol and accounted for about 75% of the total secreted proteins.	Methanol	63-71	angiopoietin 2	Rattus norvegicus	34-38
20817457-4	2010	NCL-Hamlet antibody (mouse monoclonal), following fixation in acetone/methanol, provided the strongest and most reliable staining in sections of human muscle as well as of dog and mouse muscle.	Methanol	70-78	nucleolin	Homo sapiens	0-3
21374984-5	2010	The recombinant human soluble TRAIL was secreted into the BMMY media under the condition of 3% methanol.	Methanol	95-103	TNF superfamily member 10	Homo sapiens	30-35
20967906-3	2010	The solid-state structure of the Co(II)-Borromeate reveals that six MeOH molecules, arranged in a [O--H...O] hydrogen bonded, chair-like conformation, are located within its oxophilic central cavity.	Methanol	68-72	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	33-50
20961147-3	2010	Thus, the reaction of hmpH with Mn(O(2)CPh)(2) in CH(2)Cl(2)/MeOH led to isolation of octanuclear complex 1, whereas the analogous reaction in the presence of NEt(3) gave hexadecanuclear complex 2.	Methanol	61-65	hematopoietically expressed homeobox	Homo sapiens	22-26
20455033-6	2010	The methylotrophic yeast, Pichia pastoris GS115 strain, was transformed with this cassette, and methanol utilizing (mut+) transformants were selected for production and secretion of human t-PA into culture media.	Methanol	96-104	chromosome 20 open reading frame 181	Homo sapiens	188-192
20937259-4	2010	Our initial results showed that methanol, ethanol, isopropanol, isobutanol, and isoamyl alcohol bind in the active site of CYP3A4 and exhibit type I spectra.	Methanol	32-40	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	123-129
20555363-2	2010	To investigate the role of methylotrophy in the cycling of carbon in this unusual environment, stable-isotope probing (SIP) was carried out using the one-carbon compounds methane, methanol and methylamine.	Methanol	180-188	tumor protein p53 inducible nuclear protein 1	Homo sapiens	95-123
20729275-3	2010	The purpose of this study was to investigate the effects of organic solvents such as methanol, acetonitrile, dimethyl sulfoxide (DMSO), acetone, and ethanol on CYP1A, CYP2C, CYP2D, CYP2E, and CYP3A-mediated metabolism using RLM.	Methanol	85-93	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	181-186
20729275-3	2010	The purpose of this study was to investigate the effects of organic solvents such as methanol, acetonitrile, dimethyl sulfoxide (DMSO), acetone, and ethanol on CYP1A, CYP2C, CYP2D, CYP2E, and CYP3A-mediated metabolism using RLM.	Methanol	85-93	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	192-197
21351542-5	2010	The expression of P. pastoris GS115/pPIC9K-attacin were induced with methanol.	Methanol	69-77	attacin-A-like	Musca domestica	43-50
20852764-2	2010	SPI-U membrane exhibited dramatically improved methanol permeability, oxidative stability, proton conductivity, and selectivity relative to those of the standard SPI.	Methanol	47-55	chromogranin A	Homo sapiens	0-3
19924387-2	2010	The methanol and acetone extracts of leaves harvested in February exhibit potent inhibition of hG-IIA (IC(50) = 50 and 70 microg/ml, respectively).	Methanol	4-12	glucosidase II alpha subunit	Homo sapiens	95-101
20886853-11	2010	NPCs/Pt is applied as an electrocatalyst showing excellent catalytic efficiency toward methanol oxidation in comparison to commercial E-TEK (Pt/C) catalyst.	Methanol	87-95	TEK receptor tyrosine kinase	Homo sapiens	136-139
20836560-7	2010	Moreover, another unique responsiveness is discovered for the film state: that is, the film color is varied when it is exposed to the vapor of water or methanol (vaporchromism), resulting from the structural change of PT1 occurring even in the film state.	Methanol	152-160	zinc finger protein 77	Homo sapiens	218-221
20820611-8	2010	The reaction of 2 with cobalt acetate using LiOMe/pyridine as base in methanol, under solvothermal conditions, produces a dinuclear Co(ii) complex, [Co(2)(SbAr)(2)(O(3)P(t)Bu)(3)O(2)(OMe)(2)(py)(2)] 14, with two Co(II) and two Sb centres at the vertices of a distorted tetrahedron.	Methanol	70-78	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	132-138
20820611-8	2010	The reaction of 2 with cobalt acetate using LiOMe/pyridine as base in methanol, under solvothermal conditions, produces a dinuclear Co(ii) complex, [Co(2)(SbAr)(2)(O(3)P(t)Bu)(3)O(2)(OMe)(2)(py)(2)] 14, with two Co(II) and two Sb centres at the vertices of a distorted tetrahedron.	Methanol	70-78	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	212-218
20733992-7	2010	A "syn" geometry is found for the partially protonated dimeric complexes which is preserved in methanol solution.	Methanol	95-103	synemin	Homo sapiens	3-6
20691749-3	2010	Total phenolic content found in methanol extracts of SM1-SM5 ranged from 739.36 +- 1.59 to 1116.13 +- 7.30 gallic acid equivalents mg/100g extract and total flavonoid content from 1991.29 +- 6.32 to 3954.20 +- 6.06 catechin equivalents mg/100 g extract.	Methanol	32-40	SM1	Homo sapiens	53-56
21052941-1	2010	This study investigated a methanol extract from the leaf and stem of Vitis amurensis (Vitaceae) for possible neuroprotective effects on neurotoxicity induced by amyloid beta protein (Abeta) (25-35) in cultured rat cortical neurons and also for antidementia activity in mice.	Methanol	26-34	amyloid beta (A4) precursor protein	Mus musculus	183-188
20652985-5	2010	Here, we use the one-step perturbation technique to predict the change of the free enthalpy of folding of a beta-peptide in methanol solution due to changing a variety of force-field parameters.	Methanol	124-132	amyloid beta precursor protein	Homo sapiens	106-112
20828312-9	2010	MeOH extracts reduced the level of topoisomerase IIalpha but increased the level of p27(Kip1), with no significant effect on p21(Cip1/waf1).	Methanol	0-4	zinc ribbon domain containing 2	Homo sapiens	84-87
20828312-9	2010	MeOH extracts reduced the level of topoisomerase IIalpha but increased the level of p27(Kip1), with no significant effect on p21(Cip1/waf1).	Methanol	0-4	cyclin dependent kinase inhibitor 1B	Homo sapiens	88-92
20683519-0	2010	Reversible conformational change of cytochrome c at a modified gold electrode in methanol.	Methanol	81-89	cytochrome c, somatic	Homo sapiens	36-48
21121258-3	2010	This paper describes the hepatoprotective effects of the methanol extract and four isolated compounds from Ficus chlamydocarpa on CCl4-induced liver damage, as well as the possible antioxidant mechanisms involved in this protection.	Methanol	57-65	C-C motif chemokine ligand 4	Rattus norvegicus	130-134
21121258-5	2010	Pretreatment of rats with the methanol extract of F. chlamydocarpa before CCl4 administration, significantly prevented serum increase of hepatic enzyme markers, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT), in a dose-dependent manner.	Methanol	30-38	glutamic--pyruvic transaminase	Rattus norvegicus	207-238
21121258-5	2010	Pretreatment of rats with the methanol extract of F. chlamydocarpa before CCl4 administration, significantly prevented serum increase of hepatic enzyme markers, glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT), in a dose-dependent manner.	Methanol	30-38	glutamic--pyruvic transaminase	Rattus norvegicus	240-243
20795624-4	2010	pTB adopts a single right-handed beta(6.3)-helical structure in a 1:1 mixture of methanol/chloroform with a length of approximately 45 A and a hydrophilic pore of ca.	Methanol	81-89	polypyrimidine tract binding protein 1	Homo sapiens	0-3
21587422-2	2010	The hy-droxy unit of the neutral ligand is a hydrogen-bond donor to the methanol O atom and the alk-oxy O atom of the monoanionic ligand is a hydrogen-bond acceptor to the methanol O atom.	Methanol	172-180	ALK receptor tyrosine kinase	Homo sapiens	96-99
20616203-5	2010	The cytokine upregulation was observed in vitro at methanol concentrations as low as 0.08% (25mM) as measured by interleukin-2, interferon-gamma, and tumor necrosis factor-alpha release in T cells.	Methanol	51-59	interleukin 2	Homo sapiens	113-126
20616203-5	2010	The cytokine upregulation was observed in vitro at methanol concentrations as low as 0.08% (25mM) as measured by interleukin-2, interferon-gamma, and tumor necrosis factor-alpha release in T cells.	Methanol	51-59	interferon gamma	Homo sapiens	128-177
20683519-1	2010	Changes in the secondary structure of cytochrome c on immersion in methanol were monitored using circular dichroism.	Methanol	67-75	cytochrome c, somatic	Homo sapiens	38-50
20381624-4	2010	SDS-PAGE and western blotting analysis of culture medium from methanol-induced expression yeast clones demonstrated that the rPDX1 was secreted into the culture medium, had a molecular weight by SDS-PAGE of 50kDa, and was glycosylated.	Methanol	62-70	pancreatic and duodenal homeobox 1	Rattus norvegicus	125-130
20435472-3	2010	Based on the investigation of the effects of operating conditions, including methanol to oil molar ration, catalyst concentrations and temperatures, the time course of the reaction path for the reactant composition in the ternary phase diagram of oil-FAME-MeOH offers an effective way to understand the operation of membrane reactors in the biodiesel production.	Methanol	256-260	benign adult familial myoclonic epilepsy 1	Homo sapiens	251-255
20632329-1	2010	Dimethyl adipate (DMA) was synthesized by immobilized Candida antarctica lipase B-catalyzed esterification of adipic acid and methanol.	Methanol	126-134	PAN0_003d1715	Moesziomyces antarcticus	73-79
20482279-0	2010	Effect of lycopene on caspase-3 enzyme activation in liver of methanol-intoxicated rats: comparison with fomepizole.	Methanol	62-70	caspase 3	Rattus norvegicus	22-31
20482279-7	2010	Methanol administration significantly increased the MDA level and caspase-3 activity in liver.	Methanol	0-8	caspase 3	Rattus norvegicus	66-75
20482279-9	2010	Similarly, lycopene and fomepizole decreased methanol-induced caspase-3 activity.	Methanol	45-53	caspase 3	Rattus norvegicus	62-71
20482279-12	2010	It was demonstrated for the first time that both lycopene and fomepizole prevent methanol-induced hepatic injury by reducing the increase of lipid oxidation and caspase-3 activation.	Methanol	81-89	caspase 3	Rattus norvegicus	161-170
20044800-1	2010	The effect of the methanol extract of Withania somnifera (mWS) on the gonadotropin releasing hormone (GnRH) neuron was examined in juvenile mice using the whole cell patch clamp technique.	Methanol	18-26	gonadotropin releasing hormone 1	Mus musculus	102-106
21506498-2	2010	Aim of the study was to investigate the methanol and aqueous extracts of heartwood of C. sappan for its hepatoprotective activity against CCl4 induced toxicity in freshly isolated rat hepatocytes and animals.	Methanol	40-48	C-C motif chemokine ligand 4	Rattus norvegicus	138-142
20491943-0	2010	Trm2p-dependent derepression is essential for methanol-specific gene activation in the methylotrophic yeast Candida boidinii.	Methanol	46-54	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	0-5
20491943-1	2010	We identified a gene, designated TRM2, responsible for methanol-inducible gene expression in the methylotrophic yeast Candida boidinii.	Methanol	55-63	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	33-37
20491943-4	2010	Trm2p was necessary for the activation of five methanol-inducible promoters tested.	Methanol	47-55	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	0-5
20491943-6	2010	A chromatin immunoprecipitation assay revealed that Trm2p specifically bound to the promoters of the alcohol oxidase gene (AOD1) and the dihydroxyacetone synthase gene in cells grown on methanol or oleate, but did not bind to these promoters in cells grown on glucose.	Methanol	186-194	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	52-57
20491943-8	2010	These results suggest that Trm2p-dependent derepression is essential for the Trm1p-dependent methanol-specific gene activation in C. boidinii.	Methanol	93-101	tRNA (uracil(54)-C(5))-methyltransferase	Saccharomyces cerevisiae S288C	27-32
20472730-7	2010	During fermentative production of recombinant enzymes in methanol medium, 1 ml of P. pastoris culture supernatant was found to contain approximately 3 ng of Sub2, while the enzyme was not detected during growth in a medium containing glycerol as a carbon source.	Methanol	57-65	ATP-dependent RNA helicase SUB2	Saccharomyces cerevisiae S288C	157-161
20502835-7	2010	Changes of g(xx) and A(zz) values of the Cat-1 in ILs and methanol are very small especially compared to that of TEMPO-4-carboxylate, indicating that Cat-1 is located in a polar region of the ILs resembling the situation in methanol.	Methanol	58-66	GIT ArfGAP 1	Homo sapiens	150-155
20502835-7	2010	Changes of g(xx) and A(zz) values of the Cat-1 in ILs and methanol are very small especially compared to that of TEMPO-4-carboxylate, indicating that Cat-1 is located in a polar region of the ILs resembling the situation in methanol.	Methanol	224-232	GIT ArfGAP 1	Homo sapiens	41-46
20502835-7	2010	Changes of g(xx) and A(zz) values of the Cat-1 in ILs and methanol are very small especially compared to that of TEMPO-4-carboxylate, indicating that Cat-1 is located in a polar region of the ILs resembling the situation in methanol.	Methanol	224-232	GIT ArfGAP 1	Homo sapiens	150-155
21588188-2	2010	The methanol-coordinated Pb(II) atom is chelated by the acetate anion as well as by the quinoline-2-carboxyl-ate anion.	Methanol	4-12	submaxillary gland androgen regulated protein 3B	Homo sapiens	25-31
20388532-9	2010	Experiments with organic solvents demonstrated that HvXET6 tolerated DMSO, glycerol, methanol and 1,4-butanediol in 20% (v/v) concentrations.	Methanol	85-93	XET6	Hordeum vulgare	52-58
19760099-5	2010	The expression of recombinant human IL-22 (rhIL-22) was induced by methanol and accounted for about 85% of the total secreted proteins.	Methanol	67-75	interleukin 22	Homo sapiens	36-41
20495715-2	2010	Complex 2 crystallized from a mixture of chloroform and methanol in orthorhombic crystal system, space group Iba2.	Methanol	56-64	allograft inflammatory factor 1 like	Homo sapiens	109-113
20233605-5	2010	The optimal incubation period and methanol concentrations for induction were determined for production of rSm1 in shake flasks.	Methanol	34-42	opiorphin prepropeptide	Rattus norvegicus	106-110
20233605-6	2010	One Pichia transformant was estimated to express approximately 55 mg/l of rSm1 after 4 days culture in a 1% final concentration of methanol.	Methanol	131-139	opiorphin prepropeptide	Rattus norvegicus	74-78
20473435-1	2010	Reactions of MnX(2) meltsalt (X = Cl and ClO(4)) and a quinquedentate Schiff base ligand together with its coligand azides in MeOH produced the unprecedented assembly of novel octa- and hexadecanuclear manganese clusters containing two and four alternant tetrahedral Mn(III)(3)Mn(II) cores bridged by Schiff base ligands and versatile azides groups.	Methanol	126-130	keratin 86	Homo sapiens	13-16
20527030-3	2010	The results obtained show that complete disruption of the heme-protein interactions occurs when Mb is subjected to one of the following solution conditions: pH 3.2-3.6, or solution containing 20-30% acetonitrile or 40-50% methanol.	Methanol	222-230	myoglobin	Homo sapiens	96-98
20572727-5	2010	The relative single point MP2 energies among conformers are noticeably different from those obtained with DFT for the larger methyl lactate-methanol complexes.	Methanol	140-148	tryptase pseudogene 1	Homo sapiens	26-29
20651341-1	2010	Real-time PCR-based molecular diagnostic techniques were used for the comparative identification of the most common KRAS and BRAF mutations from methanol liquid-based cytology samples and matched, formalin-fixed and paraffin-embedded tissue samples.	Methanol	145-153	KRAS proto-oncogene, GTPase	Homo sapiens	116-120
20651341-1	2010	Real-time PCR-based molecular diagnostic techniques were used for the comparative identification of the most common KRAS and BRAF mutations from methanol liquid-based cytology samples and matched, formalin-fixed and paraffin-embedded tissue samples.	Methanol	145-153	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	125-129
20430092-5	2010	RESULTS: Methanol and aqueous extracts of Phaseolus trilobus reduced elevated level of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin and hydroxyproline significantly (p&lt;0.01) in bile duct ligated Wistar rats, proving hepatoprotective activity comparable with Silymarin.	Methanol	9-17	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	119-145
20430092-5	2010	RESULTS: Methanol and aqueous extracts of Phaseolus trilobus reduced elevated level of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), bilirubin and hydroxyproline significantly (p&lt;0.01) in bile duct ligated Wistar rats, proving hepatoprotective activity comparable with Silymarin.	Methanol	9-17	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	147-150
20338193-5	2010	FTIR spectra showed similar predominant beta-sheet conformation of mixed fibroin and heavy-chain fibroin scaffolds after treated with methanol, whereas the predominant structure of light-chain fibroin was random coil conformation.	Methanol	134-142	fibroin light chain	Bombyx mori	97-104
20338193-5	2010	FTIR spectra showed similar predominant beta-sheet conformation of mixed fibroin and heavy-chain fibroin scaffolds after treated with methanol, whereas the predominant structure of light-chain fibroin was random coil conformation.	Methanol	134-142	fibroin light chain	Bombyx mori	97-104
20631889-3	2010	The methanol extracts suppressed melittin-induced [(3)H]AA release in a concentration-dependent manner in RAW 264.7 cells, and inhibited cPLA(2)/sPLA(2)-induced hydrolysis of [(14)C]AA-PC in a concentration- and time-dependent manner.	Methanol	4-12	phospholipase A2, group IVA (cytosolic, calcium-dependent)	Mus musculus	137-144
20631889-3	2010	The methanol extracts suppressed melittin-induced [(3)H]AA release in a concentration-dependent manner in RAW 264.7 cells, and inhibited cPLA(2)/sPLA(2)-induced hydrolysis of [(14)C]AA-PC in a concentration- and time-dependent manner.	Methanol	4-12	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	145-151
20631889-4	2010	A Dixon plot showed that the inhibition by methanol extracts on cPLA(2) and sPLA(2) appeared to be competitive with inhibition constants (K(i)) of 3.7microg/ml and 12.6microg/ml, respectively.	Methanol	43-51	phospholipase A2, group IVA (cytosolic, calcium-dependent)	Mus musculus	64-71
20631889-4	2010	A Dixon plot showed that the inhibition by methanol extracts on cPLA(2) and sPLA(2) appeared to be competitive with inhibition constants (K(i)) of 3.7microg/ml and 12.6microg/ml, respectively.	Methanol	43-51	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	76-82
20631889-5	2010	These data suggest that methanol extracts of Morinda citrifolia inhibits both Ca(2+)-dependent PLA(2) such as, cPLA(2) and sPLA(2).	Methanol	24-32	phospholipase A2, group IVA (cytosolic, calcium-dependent)	Mus musculus	111-118
20631889-5	2010	These data suggest that methanol extracts of Morinda citrifolia inhibits both Ca(2+)-dependent PLA(2) such as, cPLA(2) and sPLA(2).	Methanol	24-32	phospholipase A2, group IIA (platelets, synovial fluid)	Mus musculus	123-129
20013814-1	2010	The time-resolved fluorescence technique based on melanin-concentrating hormone (MCH) receptor subtype-1 (MCH-1 receptor) binding assay was adopted to carry out a bioassay-guided fractionation of the methanol extract of Morus alba leaves.	Methanol	200-208	pro-melanin concentrating hormone	Homo sapiens	81-84
20041433-1	2010	The effects of aqueous-methanol extract of Saussurea lappa Clarke root (Sl.Cr) was investigated against D-galactosamine (D-GalN) and lipopolysaccharide (LPS)-induced hepatitis in mice.	Methanol	23-31	galanin and GMAP prepropeptide	Mus musculus	123-127
20364836-3	2010	In refluxing methanol, [RuCl(2)(eta(6)-p-cymene)(P-Ph(2)PAr)] gradually undergoes chloride ion dissociation to afford the P,N-chelate, [RuCl(eta(6)-p-cymene)(P,N-Ph(2)PAr)]Cl.	Methanol	13-21	endothelin receptor type A	Homo sapiens	32-35
20514349-10	2010	TGA/DTA data revealed that the de-solvation temperatures of the MeOH derivatives 4 - 6 were slightly higher in comparison to their hydrated counterparts.	Methanol	64-68	T-box transcription factor 1	Homo sapiens	0-3
20364836-3	2010	In refluxing methanol, [RuCl(2)(eta(6)-p-cymene)(P-Ph(2)PAr)] gradually undergoes chloride ion dissociation to afford the P,N-chelate, [RuCl(eta(6)-p-cymene)(P,N-Ph(2)PAr)]Cl.	Methanol	13-21	endothelin receptor type A	Homo sapiens	141-144
20349927-1	2010	We report the photoinduced peptide bond (C-N) of an amide unit and S-S bond fission mechanisms of the cyclic tetrapeptide [cyclo(Boc-Cys-Pro-Aib-Cys-OMe)] in methanol solvent by using high-level CASSCF/CASPT2/Amber quantum mechanical/molecular mechanical (QM/MM) calculations.	Methanol	158-166	ANIB1	Homo sapiens	141-144
20491082-1	2010	Bioassay-guided fractionation of a MeOH extract of tubers of Coleus tuberosus afforded the active anti-tumor-promoting compounds identified as the triterpenoid 2alpha,3beta-dihydroxyolean-12-en-28-oic acid (maslinic acid; CT2) and a phytosterol mixture (CT1).	Methanol	35-39	cancer/testis antigen 2	Homo sapiens	222-225
20491082-1	2010	Bioassay-guided fractionation of a MeOH extract of tubers of Coleus tuberosus afforded the active anti-tumor-promoting compounds identified as the triterpenoid 2alpha,3beta-dihydroxyolean-12-en-28-oic acid (maslinic acid; CT2) and a phytosterol mixture (CT1).	Methanol	35-39	cardiotrophin 1	Homo sapiens	254-257
20225050-4	2010	The most specific separation with Sil-CEA can be emphasized by the high separation factor (e.g., alpha = 1.39 in methanol-water (7:3, v/v) at 35 degrees C) for 17alpha and 17beta-estradiols, one of the most difficult pairs of isomers in chromatographic separation, whereas for two kinds of commercially available polymeric ODS columns as references alpha = 1.01, only, under the same conditions.	Methanol	113-121	STIL centriolar assembly protein	Homo sapiens	34-37
20225050-4	2010	The most specific separation with Sil-CEA can be emphasized by the high separation factor (e.g., alpha = 1.39 in methanol-water (7:3, v/v) at 35 degrees C) for 17alpha and 17beta-estradiols, one of the most difficult pairs of isomers in chromatographic separation, whereas for two kinds of commercially available polymeric ODS columns as references alpha = 1.01, only, under the same conditions.	Methanol	113-121	CEA cell adhesion molecule 3	Homo sapiens	38-41
20348300-2	2010	The bacteriocin structural genes entL50A and entL50B were fused to the Saccharomyces cerevisiae gene region encoding the mating pheromone alpha-factor 1 secretion signal (MFalpha1(s)) and cloned, separately and together (entL50AB), into the P. pastoris expression and secretion vector pPICZalphaA, which contains the methanol-inducible alcohol oxidase promoter (P(AOX1)) to express the fusion genes.	Methanol	317-325	enterocin J	Enterococcus faecium	45-52
20359018-0	2010	Performance of PtPd electrocatalysts in direct methanol fuel cell.	Methanol	47-55	protein tyrosine phosphatase receptor type D	Homo sapiens	15-19
19655307-3	2010	The minimum energy reaction pathway for the main product methanol formation involving two spin inversions prefers to both start and terminate on the ground quartet state, where the ground doublet intermediate CH(3)RhOH is energetically preferred, and its formation rate constant over the 300-1100 K temperature range is fitted by k(CH3RhOH) = 7.03 x 10(6) exp(-69.484/RT) dm(3) mol(-1) s(-1).	Methanol	57-65	ras homolog family member H	Homo sapiens	214-218
20179854-2	2010	The coordination sphere around Co(III) in 2 [or Ga(III) in 3.0.5CHCl(3).MeOH] is described as five-coordinate distorted trigonal bipyramid (DTBP) with O(1), N(1) and N(3) [or O(2), N(1), N(3)] lying in the equatorial plane for 2 [or 3.0.5CHCl(3).MeOH].	Methanol	72-76	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	31-38
20352678-1	2010	Mid-infrared (IR) hole burning spectra of the model tripeptide Z-Aib-Pro-NHMe (Z = benzyloxycarbonyl) in gas phase and its micro-clusters with one and two methanol molecules are presented.	Methanol	155-163	ANIB1	Homo sapiens	65-68
20352678-4	2010	While the unsolvated tripeptide as well as its one-methanol cluster prefer a gamma-turn structure, a beta-turn structure is found for the two-methanol cluster, in agreement with previous condensed phase studies.	Methanol	142-150	amyloid beta precursor protein	Homo sapiens	99-105
20234900-4	2010	First, technologies based on the production of synthesis gas, i.e., Fischer-Tropsch synthesis as well as MTO/MTP (Methanol To Olefins/Methanol To Propylene), are discussed.	Methanol	114-122	metallothionein 1B	Homo sapiens	105-112
20234900-4	2010	First, technologies based on the production of synthesis gas, i.e., Fischer-Tropsch synthesis as well as MTO/MTP (Methanol To Olefins/Methanol To Propylene), are discussed.	Methanol	134-142	metallothionein 1B	Homo sapiens	105-112
20711375-1	2010	OBJECTIVE: To investigate the total alkaloid fraction of the methanol extract of leaves of Hygrophila auriculata for its hepatoprotective activity against CCl4-induced toxicity in freshly isolated rat hepatocytes, HepG2 cells, and animal models.	Methanol	61-69	C-C motif chemokine ligand 4	Homo sapiens	155-159
20179854-2	2010	The coordination sphere around Co(III) in 2 [or Ga(III) in 3.0.5CHCl(3).MeOH] is described as five-coordinate distorted trigonal bipyramid (DTBP) with O(1), N(1) and N(3) [or O(2), N(1), N(3)] lying in the equatorial plane for 2 [or 3.0.5CHCl(3).MeOH].	Methanol	72-76	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	34-37
20179854-2	2010	The coordination sphere around Co(III) in 2 [or Ga(III) in 3.0.5CHCl(3).MeOH] is described as five-coordinate distorted trigonal bipyramid (DTBP) with O(1), N(1) and N(3) [or O(2), N(1), N(3)] lying in the equatorial plane for 2 [or 3.0.5CHCl(3).MeOH].	Methanol	246-250	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	31-38
20179854-2	2010	The coordination sphere around Co(III) in 2 [or Ga(III) in 3.0.5CHCl(3).MeOH] is described as five-coordinate distorted trigonal bipyramid (DTBP) with O(1), N(1) and N(3) [or O(2), N(1), N(3)] lying in the equatorial plane for 2 [or 3.0.5CHCl(3).MeOH].	Methanol	246-250	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	34-37
20480909-4	2010	FB1 and FB2 are removed with methanol, followed by water, then directly determined by RPLC with MS detection using selected-ion monitoring of two characteristic ions in each case.	Methanol	29-37	Protein DEHYDRATION-INDUCED 19 homolog 5	Zea mays	8-11
20026160-2	2010	Therefore, we initiated a study to screen the methanol extracts prepared from the aerial parts of 33 Turkish Scutellaria species for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, which are the key enzymes taking place in pathogenesis of Alzheimer"s disease.	Methanol	46-54	cholinesterase	Meleagris gallopavo	171-192
20026160-2	2010	Therefore, we initiated a study to screen the methanol extracts prepared from the aerial parts of 33 Turkish Scutellaria species for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, which are the key enzymes taking place in pathogenesis of Alzheimer"s disease.	Methanol	46-54	cholinesterase	Meleagris gallopavo	194-198
20026160-3	2010	Besides, the methanol extracts were tested in vitro against another enzyme, tyrosinase, which is associated with melanin hyperpigmentation.	Methanol	13-21	tyrosinase	Meleagris gallopavo	76-86
20026160-6	2010	The extracts showed weak inhibition against AChE and BChE, while the best tyrosinase inhibition was caused by the methanol extract of S. brevibracteata subsp.	Methanol	114-122	tyrosinase	Meleagris gallopavo	74-84
20026516-2	2010	The therapy for methanol poisoning is alcohol dehydrogenase (ADH) inhibitors to prevent formate accumulation.	Methanol	16-24	aldo-keto reductase family 1 member A1	Rattus norvegicus	38-59
19947967-4	2010	In contrast, the cyclophanes CP-2 and CP-3 in the aqueous medium showed structured anthracene absorption and emission spectra similar to those obtained in methanol and acetonitrile.	Methanol	155-163	ceruloplasmin	Homo sapiens	29-42
20090977-3	2010	cis-2-Aryl-3-(hydroxymethyl)aziridines were shown to be highly reluctant to undergo ring opening by LiAlH(4) and MeOH under similar reaction conditions.	Methanol	113-117	suppressor of cytokine signaling 2	Homo sapiens	0-5
20055505-0	2010	Quantum chemical modeling of methanol oxidation mechanisms by methanol dehydrogenase enzyme: effect of substitution of calcium by barium in the active site.	Methanol	29-37	malate dehydrogenase 2	Homo sapiens	62-84
20055505-1	2010	Previous experimental studies have shown that the activation energy for methanol oxidation by naturally occurring Ca(2+)-containing methanol dehydrogenase (MDH) enzyme is double the methanol activation energy by Ba(2+)-MDH.	Methanol	72-80	malate dehydrogenase 2	Homo sapiens	132-154
20055505-1	2010	Previous experimental studies have shown that the activation energy for methanol oxidation by naturally occurring Ca(2+)-containing methanol dehydrogenase (MDH) enzyme is double the methanol activation energy by Ba(2+)-MDH.	Methanol	72-80	malate dehydrogenase 2	Homo sapiens	156-159
20055505-1	2010	Previous experimental studies have shown that the activation energy for methanol oxidation by naturally occurring Ca(2+)-containing methanol dehydrogenase (MDH) enzyme is double the methanol activation energy by Ba(2+)-MDH.	Methanol	72-80	malate dehydrogenase 2	Homo sapiens	219-222
20055505-1	2010	Previous experimental studies have shown that the activation energy for methanol oxidation by naturally occurring Ca(2+)-containing methanol dehydrogenase (MDH) enzyme is double the methanol activation energy by Ba(2+)-MDH.	Methanol	132-140	malate dehydrogenase 2	Homo sapiens	156-159
20055505-1	2010	Previous experimental studies have shown that the activation energy for methanol oxidation by naturally occurring Ca(2+)-containing methanol dehydrogenase (MDH) enzyme is double the methanol activation energy by Ba(2+)-MDH.	Methanol	132-140	malate dehydrogenase 2	Homo sapiens	219-222
20055505-2	2010	However, neither the reason for this difference nor the specific transition states and intermediates involved during the methanol oxidation by Ba(2+)-MDH have been clearly stated.	Methanol	121-129	malate dehydrogenase 2	Homo sapiens	150-153
20055505-3	2010	Hence, an MDH active site model based on the well-documented X-ray crystallographic structure of Ca(2+)-MDH is selected, where the Ca(2+) is replaced by a Ba(2+) ion at the active site center, and the addition-elimination (A-E) and hydride-transfer (H-T) methanol oxidation mechanisms, already proposed in the literature for Ca(2+)-MDH, are tested for Ba(2+)-MDH at the BLYP/DNP theory level.	Methanol	253-263	malate dehydrogenase 2	Homo sapiens	10-13
20055505-3	2010	Hence, an MDH active site model based on the well-documented X-ray crystallographic structure of Ca(2+)-MDH is selected, where the Ca(2+) is replaced by a Ba(2+) ion at the active site center, and the addition-elimination (A-E) and hydride-transfer (H-T) methanol oxidation mechanisms, already proposed in the literature for Ca(2+)-MDH, are tested for Ba(2+)-MDH at the BLYP/DNP theory level.	Methanol	253-263	malate dehydrogenase 2	Homo sapiens	104-107
20055505-3	2010	Hence, an MDH active site model based on the well-documented X-ray crystallographic structure of Ca(2+)-MDH is selected, where the Ca(2+) is replaced by a Ba(2+) ion at the active site center, and the addition-elimination (A-E) and hydride-transfer (H-T) methanol oxidation mechanisms, already proposed in the literature for Ca(2+)-MDH, are tested for Ba(2+)-MDH at the BLYP/DNP theory level.	Methanol	253-263	malate dehydrogenase 2	Homo sapiens	104-107
20055505-3	2010	Hence, an MDH active site model based on the well-documented X-ray crystallographic structure of Ca(2+)-MDH is selected, where the Ca(2+) is replaced by a Ba(2+) ion at the active site center, and the addition-elimination (A-E) and hydride-transfer (H-T) methanol oxidation mechanisms, already proposed in the literature for Ca(2+)-MDH, are tested for Ba(2+)-MDH at the BLYP/DNP theory level.	Methanol	253-263	malate dehydrogenase 2	Homo sapiens	104-107
20055505-6	2010	The free energy barriers for methanol oxidation by Ba(2+)-MDH, particularly for the rate-limiting steps of both mechanisms, are almost half the corresponding barriers calculated for the case of Ca(2+)-MDH, which is in agreement with experimental observations.	Methanol	29-37	malate dehydrogenase 2	Homo sapiens	58-61
20055505-6	2010	The free energy barriers for methanol oxidation by Ba(2+)-MDH, particularly for the rate-limiting steps of both mechanisms, are almost half the corresponding barriers calculated for the case of Ca(2+)-MDH, which is in agreement with experimental observations.	Methanol	29-37	malate dehydrogenase 2	Homo sapiens	201-204
20055467-4	2010	In the case of the ET probe, a very strong fluorescence quenching of the BaP-moiety-related emission due to an efficient energy transfer (energy transfer efficiency of about 0.95 for methanol) to the SRB moiety was observed.	Methanol	183-191	chaperonin containing TCP1 subunit 4	Homo sapiens	200-203
20026516-0	2010	Ranitidine as an alcohol dehydrogenase inhibitor in acute methanol toxicity in rats.	Methanol	58-66	aldo-keto reductase family 1 member A1	Rattus norvegicus	17-38
20026516-2	2010	The therapy for methanol poisoning is alcohol dehydrogenase (ADH) inhibitors to prevent formate accumulation.	Methanol	16-24	aldo-keto reductase family 1 member A1	Rattus norvegicus	61-64
20023998-3	2010	The Co(III) complexes were tested in the hydrolytic kinetic resolution of (rac)-1,2-epoxyhexane and epoxide ring opening reactions using methanol as the nucleophile.	Methanol	137-145	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
20140805-2	2010	In the present study, bioactivity-guided fractionation of the ethyl acetate fraction of the methanol leaf extract of the plant material led to the isolation of a new flavonol glycoside (AFF1).	Methanol	92-100	AF4/FMR2 family, member 1	Rattus norvegicus	186-190
20432946-5	2010	High level of Kal was obtained in BMMY medium (pH 7.0) after 96 hours induction of 29 degrees C and 2% methanol, with the highest yield of 14 mg/L in shake flask culture.	Methanol	103-111	serpin family A member 4	Homo sapiens	14-17
19367471-1	2010	(1R,2R,3S,4R)-2-Amino-6,6-dimethylbicyclo[3.1.1]heptane-3-carboxylic acid 1 was reacted with three aldehydes and two isocyanides in methanol, in water, and under solvent-free conditions to prepare enantiomeric beta-lactams via U-4C-3CRs.	Methanol	132-140	mediator complex subunit 25	Homo sapiens	69-75
19917512-0	2010	Phenanthrene and 2,2",5,5"-PCB sorption by several soils from methanol-water solutions: the effect of weathering and solute structure.	Methanol	62-70	pyruvate carboxylase	Homo sapiens	27-30
20721276-2	2010	The CoCl(2)/paoH/L-L (1 : 2 : 1) reaction system in MeOH gives complexes [Co(III)(pao)(2)(phen)]Cl.2H(2)O (1.2H(2)O) and [Co(III)(pao)(2)(bpy)]Cl.1.5MeOH (2.1.5MeOH).	Methanol	52-56	spermine oxidase	Homo sapiens	12-16
20721276-2	2010	The CoCl(2)/paoH/L-L (1 : 2 : 1) reaction system in MeOH gives complexes [Co(III)(pao)(2)(phen)]Cl.2H(2)O (1.2H(2)O) and [Co(III)(pao)(2)(bpy)]Cl.1.5MeOH (2.1.5MeOH).	Methanol	52-56	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	74-81
20721276-2	2010	The CoCl(2)/paoH/L-L (1 : 2 : 1) reaction system in MeOH gives complexes [Co(III)(pao)(2)(phen)]Cl.2H(2)O (1.2H(2)O) and [Co(III)(pao)(2)(bpy)]Cl.1.5MeOH (2.1.5MeOH).	Methanol	52-56	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	122-129
20378978-1	2010	To evaluate the anticarcinogenic activity of methanol extract of Pleurospermum kamtschaticum (PKE), we assessed its apoptosis-inducing capability in HT-29 colon carcinoma cells.	Methanol	45-53	serine/threonine kinase 32C	Homo sapiens	94-97
19799982-1	2010	AIM OF THE STUDY: In order to elucidate immunoregulatory mechanisms of Cordyceps militaris, a methanol extract of Cordyceps militaris grown on germinated soybeans was prepared and its immunoregulatory effect in the human lung epithelial cells was investigated by examining its ability to induce IL-8 expression.	Methanol	94-102	C-X-C motif chemokine ligand 8	Homo sapiens	295-299
21462703-4	2010	The corresponding maximum COD and phenol removal rates were 71% and 75%, respectively, with methanol concentration of 500 mg COD/L for a total organic loading rate of 3.5 kg COD/(m3 x day) and a phenol loading rate of 0.6 kg/(m3 x day).	Methanol	92-100	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	26-29
20108263-0	2010	ACE applied to the quantitative characterization of benzo-18-crown-6-ether binding with alkali metal ions in a methanol-water solvent system.	Methanol	111-119	angiotensin I converting enzyme	Homo sapiens	0-3
20108263-1	2010	ACE was applied to the quantitative evaluation of noncovalent binding interactions between benzo-18-crown-6-ether (B18C6) and several alkali metal ions, Li(+), Na(+), K(+), Rb(+) and Cs(+), in a mixed binary solvent system, methanol-water (50/50 v/v).	Methanol	224-232	angiotensin I converting enzyme	Homo sapiens	0-3
21462703-4	2010	The corresponding maximum COD and phenol removal rates were 71% and 75%, respectively, with methanol concentration of 500 mg COD/L for a total organic loading rate of 3.5 kg COD/(m3 x day) and a phenol loading rate of 0.6 kg/(m3 x day).	Methanol	92-100	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	125-128
21462703-4	2010	The corresponding maximum COD and phenol removal rates were 71% and 75%, respectively, with methanol concentration of 500 mg COD/L for a total organic loading rate of 3.5 kg COD/(m3 x day) and a phenol loading rate of 0.6 kg/(m3 x day).	Methanol	92-100	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	125-128
21462703-5	2010	The phenol removal rate was not improved with a higher methanol concentration of 1000 mg COD/L.	Methanol	55-63	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	89-92
19928939-2	2009	Molecular probe experiments indicated that PB(89)-b-PEO(132) (subscripts indicate the number of monomers in each block) forms micelles with PEO cores and PB coronas in pure cyclohexane and micelles with PB cores and PEO coronas in pure methanol.	Methanol	236-244	twinkle mtDNA helicase	Homo sapiens	52-55
20024403-1	2009	Computational techniques (second order Moller-Plesset MP2 perturbation theory in conjunction with medium and large size basis sets) are applied to explore structural aspects of a hydrogen-bonded tetrameric cluster of methanol molecules, based geometrically on a tetrahedral arrangement of the four oxygen atoms of the cluster.	Methanol	217-225	tryptase pseudogene 1	Homo sapiens	54-57
19950354-6	2009	Plots of the polar and specific selectivity for select solutes versus organic modifier level are used to demonstrate the differing influences of ACN and methanol on the selectivity obtained on representative EPG and C18 stationary phases.	Methanol	153-161	Bardet-Biedl syndrome 9	Homo sapiens	216-219
19905875-2	2010	The inactivation kinetics of CYP3A4 by diazepam dissolved in acetonitrile and methanol were almost equal with k(inact)/K(I) values, 0.095 and 0.15 min(-1) mM(-1) for HLM and 1.1 and 1.4 min(-1) mM(-1) for rCYP3A4, respectively.	Methanol	78-86	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	29-35
19905875-4	2010	The formation rate of nordiazepam and temazepam metabolized from diazepam dissolved in DMSO were approximately half of those using substrate dissolved in acetonitrile and methanol in both HLM and rCYP3A4.	Methanol	171-179	oxysterol binding protein 2	Homo sapiens	188-191
19949665-3	2009	Application of MeOH extract of Lindera erythrocarpa showed a dose-dependent decrease in the amplitudes of the outward currents measured at the end of the pulse (I(HERG)) and the tail currents of HERG (I(tail)).	Methanol	15-19	potassium voltage-gated channel subfamily H member 2	Homo sapiens	163-167
19949665-3	2009	Application of MeOH extract of Lindera erythrocarpa showed a dose-dependent decrease in the amplitudes of the outward currents measured at the end of the pulse (I(HERG)) and the tail currents of HERG (I(tail)).	Methanol	15-19	potassium voltage-gated channel subfamily H member 2	Homo sapiens	195-199
19845430-4	2009	Significantly low carbinol-forming activities were seen in human liver microsomes from individuals possessing CYP2A6*4/*4 (whole CYP2A6 gene deletion) at a letrozole concentration of 0.5 microM.	Methanol	18-26	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	110-116
19788307-2	2009	In tensile stress-strain analysis, methanol-treated non-cross-linked SELP-47K films exceeded the properties of native aortic elastin, attaining an ultimate tensile strength of 2.5 +/- 0.4 MPa, an elastic modulus of 1.7 +/- 0.4 MPa, an extensibility of 190 +/- 60%, and a resilience of 86 +/- 4% after 10 cycles of mechanical preconditioning.	Methanol	35-43	selectin P	Homo sapiens	69-73
19788307-2	2009	In tensile stress-strain analysis, methanol-treated non-cross-linked SELP-47K films exceeded the properties of native aortic elastin, attaining an ultimate tensile strength of 2.5 +/- 0.4 MPa, an elastic modulus of 1.7 +/- 0.4 MPa, an extensibility of 190 +/- 60%, and a resilience of 86 +/- 4% after 10 cycles of mechanical preconditioning.	Methanol	35-43	elastin	Homo sapiens	125-132
19882627-7	2009	A monolithic C18 column with MeOH had the lowest CED at 0.675 MJ-eq, a peak capacity of 28 peaks and good resolving power (resolving ten peak pairs with R(s)&gt;1), suggesting that this is a viable option with respect to reducing environmental impact for these types of analyses.	Methanol	29-33	Bardet-Biedl syndrome 9	Homo sapiens	13-16
19826665-1	2009	Dielectric Barrier Discharges (DBD) operated at atmospheric pressure and working at reduced temperatures (T &lt; 115 degrees C) and a copper-manganese oxide catalyst are combined for the direct decomposition and the steam reforming of methanol (SRM) for hydrogen production and for the preferential oxidation of CO (CO-PROX).	Methanol	235-243	pyruvate dehydrogenase complex component X	Homo sapiens	319-323
19845430-4	2009	Significantly low carbinol-forming activities were seen in human liver microsomes from individuals possessing CYP2A6*4/*4 (whole CYP2A6 gene deletion) at a letrozole concentration of 0.5 microM.	Methanol	18-26	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	129-135
19754085-1	2009	A kinetic study of the aroxyl (ArO*) radical-scavenging reaction of alpha-tocopherol (alpha-TocH) has been performed in the presence of six kinds of alkali and alkaline earth metal salts (LiI, LiClO(4), NaI, NaClO(4), KI, and Mg(ClO(4))(2)) in methanol solution, using stopped-flow spectrophotometry.	Methanol	244-252	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	31-35
21578144-2	2009	The Co(III) cation has site symmetry m, and is coordinated by four oxygen atoms from four bridging pivalate groups, one central O anion and a methanol oxygen atom, forming a distorted octa-hedral geometry.	Methanol	142-150	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
19754085-6	2009	Effects of metal cations on the UV-vis absorption spectra of the alpha-Toc* (and ArO*) radical were negligible in methanol solution, suggesting that the complex formation between the alpha-Toc* (and ArO*) radical molecule and metal cations is hindered by the hydrogen bond between radical and methanol molecules.	Methanol	114-122	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	81-85
19754085-6	2009	Effects of metal cations on the UV-vis absorption spectra of the alpha-Toc* (and ArO*) radical were negligible in methanol solution, suggesting that the complex formation between the alpha-Toc* (and ArO*) radical molecule and metal cations is hindered by the hydrogen bond between radical and methanol molecules.	Methanol	293-301	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	81-85
19754085-6	2009	Effects of metal cations on the UV-vis absorption spectra of the alpha-Toc* (and ArO*) radical were negligible in methanol solution, suggesting that the complex formation between the alpha-Toc* (and ArO*) radical molecule and metal cations is hindered by the hydrogen bond between radical and methanol molecules.	Methanol	293-301	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	199-203
19665800-3	2009	Electrochemical data in methanol revealed that the Co(III)--&gt;Co(II) reduction of 1 (-0.84V vs. normal hydrogen electrode - NHE) is more positive than 2 (-1.13V vs. NHE), while it was expected to be more negative due to better sigma-donor ability of imidazole ring in HL1, compared to pyridine in HL2.	Methanol	24-32	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	54-57
19665800-3	2009	Electrochemical data in methanol revealed that the Co(III)--&gt;Co(II) reduction of 1 (-0.84V vs. normal hydrogen electrode - NHE) is more positive than 2 (-1.13V vs. NHE), while it was expected to be more negative due to better sigma-donor ability of imidazole ring in HL1, compared to pyridine in HL2.	Methanol	24-32	solute carrier family 9 member C1	Homo sapiens	126-129
20161330-4	2009	The MeOH extract of SPC was most potent in quenching HOCl and ONOO(-) and increasing FRAP and ORAC, but did not induce QR.	Methanol	4-8	mechanistic target of rapamycin kinase	Mus musculus	85-89
21577916-3	2009	In the crystal structure, no significant pi-pi inter-actions are present, and the mol-ecules are associated through weak C-H N and C-H O(methanol) contacts.	Methanol	137-145	chimerin 1	Homo sapiens	121-134
19660780-1	2009	Photolysis of deca-bromodiphenyl ether (BDE-209) was investigated in tetrahydrofuran, dichloromethane, isopropanol, acetone, ethanol, methanol, acetonitrile and dimethylsulfoxide.	Methanol	134-142	homeobox D13	Homo sapiens	40-43
19708669-6	2009	In methanol, the CD spectrum of somatostatin-14 keeps globally the same spectral shape as that observed in water, whereas its open analogue presents a major population of helical conformers.	Methanol	3-11	somatostatin	Homo sapiens	32-47
19705812-1	2009	High concentration-dependent halogen bonding, a specific solvent effect between carbon tetrabromide and oxygen-containing organic solvents, including methanol, ethanol, acetone, dioxane, diethyl ether, and tetrahydrofuran, was found to coexist with the general solvent effect when CBr4 was over 7.8 x 10(-3) M approximately 1.6 x 10(-2) M critical concentration range.	Methanol	150-158	carbonyl reductase 4	Homo sapiens	281-285
19796482-6	2009	We have applied in situ attenuated total reflection infrared (ATR-IR) spectroscopy for elucidating and monitoring the acetalization of cyclohexanone in CO(2)-expanded ethylene glycol and methanol at 50 degrees C and 3 MPa.	Methanol	187-195	ATR serine/threonine kinase	Homo sapiens	62-65
19433133-3	2009	Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC(50) value of 4.27 microg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC(50) values of 2.12 and 3.71 microg/ml, respectively.	Methanol	0-8	carbonic anhydrase 2	Homo sapiens	47-68
19433133-3	2009	Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC(50) value of 4.27 microg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC(50) values of 2.12 and 3.71 microg/ml, respectively.	Methanol	0-8	cathepsin B	Homo sapiens	168-179
19433133-3	2009	Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC(50) value of 4.27 microg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC(50) values of 2.12 and 3.71 microg/ml, respectively.	Methanol	129-137	carbonic anhydrase 2	Homo sapiens	47-68
19433133-3	2009	Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC(50) value of 4.27 microg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC(50) values of 2.12 and 3.71 microg/ml, respectively.	Methanol	129-137	cathepsin B	Homo sapiens	168-179
19631328-6	2009	An addition of methanol modifier (30%, v/v) into 10 mM borate buffer (pH 9.55 for MEP; pH 10.0 for MES) was necessary to accomplish a baseline separation of nine flavonoids in the MEP and MES capillaries.	Methanol	15-23	neurolysin	Homo sapiens	82-85
19631328-6	2009	An addition of methanol modifier (30%, v/v) into 10 mM borate buffer (pH 9.55 for MEP; pH 10.0 for MES) was necessary to accomplish a baseline separation of nine flavonoids in the MEP and MES capillaries.	Methanol	15-23	neurolysin	Homo sapiens	180-183
19450864-3	2009	Although methanol extracts of RM displayed high AhR activity, none of the aqueous extracts of RM had significant activity.	Methanol	9-17	aryl hydrocarbon receptor	Homo sapiens	48-51
19575368-2	2009	According to experiment, the two peptides differ in the dominant fold when solvated in methanol: one shows a helical fold, the other a beta hairpin.	Methanol	87-95	amyloid beta precursor protein	Homo sapiens	133-139
20161398-3	2009	The reaction in methanol requires reflux to dissolve the lipophilic ligand and generates the fac isomer of [TcCl2(NO)(PNPpr)] as the major product, with the tridentate ligand in a facial arrangement, leaving the chlorides and nitrosyl ligand in the remaining facial sites.	Methanol	16-24	FA complementation group C	Homo sapiens	93-96
19535124-0	2009	Mechanism of the degradation of individual PCB congeners using mechanically alloyed Mg/Pd in methanol.	Methanol	93-101	pyruvate carboxylase	Homo sapiens	43-46
19469902-2	2009	The active 80% methanol chromatographic fraction from the ethyl acetate layer [partial purification from C. longa (PPC)] was used to investigate the alpha-melanocyte-stimulating hormone (alpha-MSH)-stimulated melanogenesis signal pathway in B16F10 cells.	Methanol	15-23	pro-opiomelanocortin-alpha	Mus musculus	187-196
19435638-2	2009	The organic carbon-normalized sorption coefficients (K(OC)) for diuron and phenanthrene (determined from single initial concentrations of 0.8mgL(-1) and 1.5mgL(-1), respectively) were consistently higher following solvent-conditioning of a whole soil with five organic solvents (acetonitrile, acetone, methanol, chloroform and dichloromethane).	Methanol	302-310	insulin like growth factor 2 mRNA binding protein 3	Homo sapiens	53-58
19451401-6	2009	The comparatively higher inhibitory effects of DMSO relative to that for acetonitrile and methanol on LIPA metabolism were consistent with its known CYP3A4 inhibitory effects reported by others.	Methanol	90-98	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	149-155
19555177-4	2009	Of the extracts and organic fractions of L. chinensis tested, a MeOH extract and an EtOAc fraction were found to be potent inhibitors of rat lens aldose reductase (RLAR) in vitro--their IC(50) values being 3.6 and 0.3 microg/mL, respectively.	Methanol	64-68	aldo-keto reductase family 1 member B1	Rattus norvegicus	146-162
19416959-7	2009	When recombinant ATX was incubated with LPC in the presence of methanol, both LPM and LPA were produced with a ratio of 1:10, showing that ATX has transphosphatidylation activity in addition to its lysophospholipase D activity.	Methanol	63-71	ectonucleotide pyrophosphatase/phosphodiesterase 2	Mus musculus	17-20
19416959-7	2009	When recombinant ATX was incubated with LPC in the presence of methanol, both LPM and LPA were produced with a ratio of 1:10, showing that ATX has transphosphatidylation activity in addition to its lysophospholipase D activity.	Methanol	63-71	ectonucleotide pyrophosphatase/phosphodiesterase 2	Mus musculus	139-142
19165747-2	2009	The methanol extract was identified as a potent in vitro inhibitor of rat brain GABA transaminase (GABA-T), an enzyme target in the therapy of anxiety, epilepsy and related neurological disorders.	Methanol	4-12	4-aminobutyrate aminotransferase	Rattus norvegicus	80-97
19165747-2	2009	The methanol extract was identified as a potent in vitro inhibitor of rat brain GABA transaminase (GABA-T), an enzyme target in the therapy of anxiety, epilepsy and related neurological disorders.	Methanol	4-12	4-aminobutyrate aminotransferase	Rattus norvegicus	99-105
19569196-3	2009	Practically insoluble in water, farnesol can be extracted from production cultures of the erg9 mutants using either methanol/hexane or poly(styrene-co-divinylbenzene) beads.	Methanol	116-124	bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase	Saccharomyces cerevisiae S288C	90-94
19569705-3	2009	The S(1)-S(0) spectra of TrpH(+)(CH(3)OH)(n) clusters exhibit a drastic change with the number of methanol molecules.	Methanol	98-106	tryptophan hydroxylase 1	Homo sapiens	25-29
19569705-5	2009	Ala-TrpH(+) and Gly-TrpH(+) exhibit an extensive spectral change with addition of two methanol molecules.	Methanol	86-94	tryptophan hydroxylase 1	Homo sapiens	4-8
19569705-5	2009	Ala-TrpH(+) and Gly-TrpH(+) exhibit an extensive spectral change with addition of two methanol molecules.	Methanol	86-94	tryptophan hydroxylase 1	Homo sapiens	20-24
19400569-1	2009	Functionalized furans are conveniently formed by a new silver(I)-catalyzed reaction of alk-1-ynyl oxiranes in the presence of p-toluenesulfonic acid and methanol.	Methanol	153-161	secretory leukocyte peptidase inhibitor	Homo sapiens	87-92
19791498-2	2009	The in vitro cytotoxic activity assay against two human cancer cell lines, large lung carcinoma (CORL-23) and amelanotic melanoma (C32), showed that the most antiproliferative extract was the MeOH extract from flowers with a percentage of inhibition of 50.9 at 100 microg/ml against amelanotic melanoma cells.	Methanol	192-196	chemokine like factor	Homo sapiens	131-134
19473794-8	2009	Strong cytotoxicity was shown by the methylene chloride extract of Michelia champaca bark and the methanol extract of Curcuma longa rhizome against C32 and HeLa, respectively.	Methanol	98-106	chemokine like factor	Homo sapiens	148-151
19473794-10	2009	The methanol extract of Bouea burmanica had a slightly lower activity towards C32 cells than did Michelia champaca but had a much higher SI (&gt;27,000).	Methanol	4-12	chemokine like factor	Homo sapiens	78-81
19450714-0	2009	Identification of key DNA elements involved in promoter recognition by Mxr1p, a master regulator of methanol utilization pathway in Pichia pastoris.	Methanol	100-108	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	71-76
18936942-5	2009	Mut(s) multiple insert transformants were screened by G418 and induced by 5 mL/L methanol to express soluble ScFv.	Methanol	81-89	immunglobulin heavy chain variable region	Homo sapiens	109-113
18936942-6	2009	After 6 days of methanol induction, anti-keratin ScFv was efficiently secreted into the medium.	Methanol	16-24	immunglobulin heavy chain variable region	Homo sapiens	49-53
19450714-1	2009	Mxr1p (methanol expression regulator 1) functions as a key regulator of methanol metabolism in the methylotrophic yeast Pichia pastoris.	Methanol	7-15	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	0-5
19450714-1	2009	Mxr1p (methanol expression regulator 1) functions as a key regulator of methanol metabolism in the methylotrophic yeast Pichia pastoris.	Methanol	72-80	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	0-5
19450714-9	2009	The identification of key DNA elements involved in promoter recognition by Mxr1p is an important step in understanding its function as a master regulator of the methanol utilization pathway in P. pastoris.	Methanol	161-169	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	75-80
19629659-6	2009	Myoglobin was dissolved in pure methanol, ethylene glycol and glycerol.	Methanol	32-40	myoglobin	Homo sapiens	0-9
19551732-1	2009	The MeOH extract and its BuOH-soluble fraction (crude saponin fraction) from the flower buds of Chinese tea plant (Camellia sinensis (L.) O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase.	Methanol	4-8	pancreatic lipase	Mus musculus	276-293
19557354-4	2009	The secreted form of hCAP18/LL37 exhibited its maximum activity after 72 h incubation with 2% methanol in MM media, not in BMM.	Methanol	94-102	cathelicidin antimicrobial peptide	Homo sapiens	21-27
20442817-0	2009	Hepatoprotective activity of petroleum ether, diethyl ether, and methanol extract of Scoparia dulcis L. against CCl4-induced acute liver injury in mice.	Methanol	65-73	chemokine (C-C motif) ligand 4	Mus musculus	112-116
19420699-2	2009	Principal components analysis (PCA) allowed the clear separation of 50% methanol extracts from fermented soymilk with different fermentation times by combining principal components PC1 and PC3, which accounted for 55.1% of the total variance.	Methanol	72-80	proprotein convertase subtilisin/kexin type 1	Homo sapiens	181-184
19374427-1	2009	This study examines the effects of electrolytes on microcystin (MC) electrospray ionization (ESI) mass spectrometry and quantitative LC-MS-MS. Sodium replacement ions (SRI) are prominent in MC ESI spectra in protic solvents such as HPLC grade methanol.	Methanol	243-251	sorcin	Homo sapiens	168-171
19374427-2	2009	In a methanol-water-0.006% acetic acid (v/v) gradient, envelopes with up to 11 SRI were apparent in both the +1 and +2 charge states with structures [M + Na(x) - (x-1)H](+) and [M + Na(x) - (x-2)H](+2).	Methanol	5-13	sorcin	Homo sapiens	79-82
19232637-0	2009	Effect of concentration of methanol for the control of particle size and size-dependent SERS studies.	Methanol	27-35	seryl-tRNA synthetase 1	Homo sapiens	88-92
19232637-10	2009	The variable size of the particles, obtained in a water methanol system, was employed for SERS measurement.	Methanol	56-64	seryl-tRNA synthetase 1	Homo sapiens	90-94
19420699-2	2009	Principal components analysis (PCA) allowed the clear separation of 50% methanol extracts from fermented soymilk with different fermentation times by combining principal components PC1 and PC3, which accounted for 55.1% of the total variance.	Methanol	72-80	proprotein convertase subtilisin/kexin type 1	Homo sapiens	189-192
19217780-1	2009	A MeOH extract of the dry root of Lithospermum erythrorhizon showed strong increasing effect on serine palmitoyltransferase (SPT) in normal human keratinocyte cells (HaCaT cells).	Methanol	2-6	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	125-128
19203594-2	2009	The optimal SFE conditions were 80 degrees C, 300 kg/cm(2), 30% methanol for 40 min as a dynamic extraction time, in addition to 0.2g Na(4)EDTA and 7.0 g sea sand in the extraction vessel.	Methanol	64-72	membrane metalloendopeptidase	Sus scrofa	12-15
19090684-7	2009	In contrast, solvation in methanol retards the quenching process of the retinal protonated Schiff base (RPSB), the rhodopsin chromophore.	Methanol	26-34	rhodopsin	Homo sapiens	115-124
19232631-5	2009	Electrochemical measurements show that the molecular monolayers do not impede redox behavior of the electrode, and measurements of the electrocatalytic oxidation of methanol show very high catalytic efficiency compared with commercial E-TEK Pt/C (20 wt%) catalysts, which is crucial for anode electrocatalysis in direct methanol fuel cells.	Methanol	165-173	TEK receptor tyrosine kinase	Homo sapiens	237-240
19405592-3	2009	A third mechanism, the almost thermoneutral abstraction of a hydrogen atom from methanol parent molecule by the photolytically produced hydrogen atom, yields translationally and rotationally cold H(2)(v=0 and 1) products.	Methanol	80-88	immunoglobulin kappa variable 1-5	Homo sapiens	201-210
19215105-2	2009	Hydrolysis of the ester with methanol and basic alumina provides, in good to excellent overall yield, a 5-hydroxycyclopent-2-enone in which the alcohol is predominantly trans to a substituent at C-4.	Methanol	29-37	complement C4A (Rodgers blood group)	Homo sapiens	195-198
19382701-2	2009	The mutant strains possessed defects in genes MTH1 and MTH2 which resulted in the inability to assimilate methanol as a sole carbon source and the increased activity of alcohol oxidase (AO).	Methanol	106-114	Mth1p	Saccharomyces cerevisiae S288C	46-50
19034430-5	2009	The same sediment samples were also probed for genes coding for methanol dehydrogenase (MDH) (catalyzing the oxidation of methanol to formaldehyde) to assess specifically changes in methylotrophic bacterial populations in the site.	Methanol	64-72	malate dehydrogenase 2	Homo sapiens	88-91
19350940-2	2009	FMNH2 was produced in methanol solvent by the photoreduction of FMN.	Methanol	22-30	formin 1	Homo sapiens	0-3
19680900-4	2009	Subsequently, the vitamin B12 immunoaffinity column was washed with 10 ml water and the vitamin B12 was released from the column with 3 ml methanol.	Methanol	139-147	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	96-99
18844258-1	2009	A 96-well microplate filtration based 5-HT(2A) receptor-radioligand binding assay was optimized and adopted to carry out a bioassay-guided fractionation of the methanol extract of the leaves of Litsea sessilis.	Methanol	160-168	5-hydroxytryptamine receptor 2A	Homo sapiens	38-55
19382701-6	2009	The restoration of growth of four spontaneous revertants of the mutant mth1 (Rmth1) on the methanol containing medium was accompanied by an increase in activity of AO isogenic form 9 and peroxisomal catalase.	Methanol	91-99	Mth1p	Saccharomyces cerevisiae S288C	71-75
19448924-2	2009	In toxicity tests on Artemia salina, the hexane and methanol extracts from avocado seeds showed LC50 values of 2.37 and 24.13 mg mL-1 respectively.	Methanol	52-60	L1 cell adhesion molecule	Mus musculus	129-133
19283282-0	2009	Reversible increase in the redox potential of cytochrome c in methanol.	Methanol	62-70	cytochrome c, somatic	Homo sapiens	46-58
19448924-3	2009	Against Aedes aegypti larvae, the LC50 results obtained were 16.7 mg mL-1 for hexane extract and 8.87 mg mL-1 for methanol extract from avocado seeds.	Methanol	114-122	L1 cell adhesion molecule	Mus musculus	105-109
19448924-5	2009	The minimal inhibitory concentration for the methanol extract ranged from 0.125 to 0.625 mg mL-1, from 0.08 to 0.156 mg mL-1 and from 0.312 to 0.625 mg mL-1, for the strains of Candida spp., Cryptococcus neoformans and Malassezia pachydermatis, respectively.	Methanol	45-53	L1 cell adhesion molecule	Mus musculus	92-96
19448924-5	2009	The minimal inhibitory concentration for the methanol extract ranged from 0.125 to 0.625 mg mL-1, from 0.08 to 0.156 mg mL-1 and from 0.312 to 0.625 mg mL-1, for the strains of Candida spp., Cryptococcus neoformans and Malassezia pachydermatis, respectively.	Methanol	45-53	L1 cell adhesion molecule	Mus musculus	120-124
19448924-5	2009	The minimal inhibitory concentration for the methanol extract ranged from 0.125 to 0.625 mg mL-1, from 0.08 to 0.156 mg mL-1 and from 0.312 to 0.625 mg mL-1, for the strains of Candida spp., Cryptococcus neoformans and Malassezia pachydermatis, respectively.	Methanol	45-53	L1 cell adhesion molecule	Mus musculus	120-124
19283282-1	2009	The E degrees " of cytochrome c on a self-assembled monolayer (SAM) modified gold electrode increased by 300 mV immediately on immersion in methanol; on re-immersion of the electrode in aqueous buffer, the original faradaic response was restored, but over a period of 120 min, indicating that methanol causes a significant change in conformation/orientation of the protein.	Methanol	140-148	cytochrome c, somatic	Homo sapiens	19-31
19283282-1	2009	The E degrees " of cytochrome c on a self-assembled monolayer (SAM) modified gold electrode increased by 300 mV immediately on immersion in methanol; on re-immersion of the electrode in aqueous buffer, the original faradaic response was restored, but over a period of 120 min, indicating that methanol causes a significant change in conformation/orientation of the protein.	Methanol	293-301	cytochrome c, somatic	Homo sapiens	19-31
18809323-4	2009	Results indicated a significant interactive effect between temperature, acid concentration, and methanol to sludge mass ratio on the FAME yield for the insitu transesterification of primary sludge, while the FAME yield for secondary sludge was significantly affected by the independent effects of the three factors investigated.	Methanol	96-104	benign adult familial myoclonic epilepsy 1	Homo sapiens	133-137
18809323-5	2009	The maximum FAME yields were obtained at 75 degrees C, 5% (v/v) H(2)SO(4), and 12:1 methanol to sludge mass ratio and were 14.5% and 2.5% for primary and secondary sludge, respectively.	Methanol	84-92	benign adult familial myoclonic epilepsy 1	Homo sapiens	12-16
19202795-3	2008	The drugs were successfully separated from major and minor degradation products on a reversed-phase C18 column by using 75 mM potassium dihydrogen phosphate buffer (pH 4.3)-acetonitrile-methanol (50 + 45 + 5, v/v/v) as the mobile phase with determination at 227 nm.	Methanol	186-194	Bardet-Biedl syndrome 9	Homo sapiens	100-103
19081970-3	2009	The reaction of 1, NEt3 and MnCl2 x 4H2O in a 2:2:1 ratio in MeOH gave the pentanulear complex 2.	Methanol	61-65	tetraspanin 2	Homo sapiens	19-23
18821128-5	2009	Results demonstrated that the surface areas obtained for chitosan from the BET analyses for heptane, 1,4-dioxane and methanol were 421, 379 and 58 m(2)/g, respectively.	Methanol	117-125	delta/notch like EGF repeat containing	Homo sapiens	75-78
19032039-2	2008	The presence of a lipophilic dodecyl appendage at imidazolium nitrogen in 3 successfully allows the selective determination of AcO(-) ions in protic (CHCl(3)-MeOH, 1:1) solvent.	Methanol	158-162	kallikrein related peptidase 15	Homo sapiens	127-130
18986144-1	2008	The mechanism of methanol carbonylation at different positions of zeolite MOR is investigated by quantum-chemical methods in order to discover which are the active sites that can selectively catalyze the desired reaction.	Methanol	17-25	opioid receptor mu 1	Homo sapiens	74-77
19075460-7	2008	A remarkable loss of sensitivity for highly-brominated congeners, such as nona- and deca-BDE, was observed in an analysis of PBDE technical mixtures when the solvent was methanol.	Methanol	170-178	homeobox D13	Homo sapiens	89-92
19131697-3	2008	By culturing of Pichia transformant on methanol medium, the human proCPB was successfully expressed and secreted into the culture supernatant.	Methanol	39-47	carboxypeptidase B1	Homo sapiens	66-72
18778740-6	2008	A Michaelis-Menten model type provided a good fit for the elimination capacity (EC) of the BTF treating methanol, while a Haldane model type provided a good fit to the EC of the BF treating methanol and toluene.	Methanol	104-112	BCL2 associated transcription factor 1	Homo sapiens	91-94
18778740-6	2008	A Michaelis-Menten model type provided a good fit for the elimination capacity (EC) of the BTF treating methanol, while a Haldane model type provided a good fit to the EC of the BF treating methanol and toluene.	Methanol	190-198	BCL2 associated transcription factor 1	Homo sapiens	91-94
18462937-3	2008	The use of an inoculum previously acclimated to high nitrate concentrations led to complete denitrification in 6h (denitrification rate: 22.8mg NO3- -N/gVSSh), using methanol as carbon source for a COD/N ratio of 4 and for a content of calcium in the wastewater of 150mg/L.	Methanol	166-174	NBL1, DAN family BMP antagonist	Homo sapiens	144-147
19124248-7	2009	Furthermore, a MeOH extract of the bark of Ardisia colorata markedly enhanced DR5 activity in this screening system.	Methanol	15-19	TNF receptor superfamily member 10b	Homo sapiens	78-81
19107825-1	2009	The human aldose reductase inhibitory effects of the methanol extracts of 17 medicinal and edible mushrooms were examined.	Methanol	53-61	aldo-keto reductase family 1 member B	Homo sapiens	10-26
18841928-1	2008	The employment of the dianion (dpkd(2-)) of the gem-diol form of di-2-pyridylketone (dpk) as a tetradentate chelate in manganese chemistry is reported, and the synthesis, crystal structure, and magnetochemical characterization of [Mn26O16(OMe)12(dpkd)12(MeOH)6](OH)6 x solv (3 x solv) are described.	Methanol	254-259	TAO kinase 3	Homo sapiens	31-34
18841928-2	2008	The reaction of Mn(ClO4)2 x 6 H2O, dpk, NaOMe, and NEt3 (2:1:4:2) in MeCN/MeOH affords complex 3, which possesses a rare metal topology and is mixed-valence (4 Mn(II), 22 Mn(III)).	Methanol	74-78	TAO kinase 3	Homo sapiens	35-38
18841928-2	2008	The reaction of Mn(ClO4)2 x 6 H2O, dpk, NaOMe, and NEt3 (2:1:4:2) in MeCN/MeOH affords complex 3, which possesses a rare metal topology and is mixed-valence (4 Mn(II), 22 Mn(III)).	Methanol	74-78	tetraspanin 2	Homo sapiens	51-55
18780387-2	2008	Incubations of linoleic acid (9S)-hydroperoxide with dilute suspensions of LeAOS3 (10-20 s, 0 degrees C) yield mostly the expected allene oxide (12Z)-9,10-epoxy-10,12-octadecadienoic acid (9,10-EOD), which was detected as its methanol-trapping product.	Methanol	226-234	allene oxide synthase 3	Solanum lycopersicum	75-81
18986200-1	2008	Phytochemical investigation of a methanol extract of Onobrychis ebenoides yielded five new 3-formyl-2-arylbenzofurans, namely, ebenfurans IV-VIII (1-5), together with the known compounds ebenfurans I, II (6), and III (7).	Methanol	33-41	cytochrome c oxidase subunit 8A	Homo sapiens	141-145
18827938-3	2008	5d can instead be prepared by reaction of d with a strongly basic methanol solution of Zeise"s anion [PtCl3(eta2-C2H4)](-), 1.	Methanol	66-74	DNA polymerase iota	Homo sapiens	108-112
18262832-2	2008	Since we took as a reference the product obtained after CL-20 irradiation in methanol solution, the nature of intermolecular bonds between heterocycles under study and methanol molecules was analyzed in detail.	Methanol	168-176	epithelial membrane protein 1	Homo sapiens	56-61
18671198-1	2008	A significant acetylcholinesterase inhibitory activity was observed for the ethyl acetate and methanol extracts from the leaves and the fruits of MYRISTICA CRASSA.	Methanol	94-102	acetylcholinesterase (Cartwright blood group)	Homo sapiens	14-34
18847468-6	2008	The aim of this study was to compare the levels of expression of the human Adenosine 2A receptor (A2AR) in P. pastoris under control of a methanol-inducible promoter in both flask and bioreactor cultures.	Methanol	138-146	adenosine A2a receptor	Homo sapiens	75-96
18847468-6	2008	The aim of this study was to compare the levels of expression of the human Adenosine 2A receptor (A2AR) in P. pastoris under control of a methanol-inducible promoter in both flask and bioreactor cultures.	Methanol	138-146	adenosine A2a receptor	Homo sapiens	98-102
18778097-6	2008	When the cellulose I-EDA complex was immersed in methanol or water at room temperature, cellulose III I or I beta was obtained, respectively.	Methanol	49-57	G protein-coupled receptor 149	Homo sapiens	19-24
18328687-4	2008	Methanol-washed soy protein compared to casein increased the mRNA expression of peroxisome proliferator-activated receptor (PPAR) alpha, and supplementing the soy protein diet with isoflavone further increased this parameter dose-dependently.	Methanol	0-8	peroxisome proliferator activated receptor alpha	Rattus norvegicus	80-135
18328687-7	2008	The mRNA level of uncoupling protein (UCP) 1 in brown adipose tissue was significantly increased and mRNA levels of UCP2 and 3, and PPARgamma2 tended to be higher in rats fed methanol-washed soy protein not supplemented with isoflavone than in the animals fed casein.	Methanol	175-183	uncoupling protein 1	Rattus norvegicus	18-44
18328687-7	2008	The mRNA level of uncoupling protein (UCP) 1 in brown adipose tissue was significantly increased and mRNA levels of UCP2 and 3, and PPARgamma2 tended to be higher in rats fed methanol-washed soy protein not supplemented with isoflavone than in the animals fed casein.	Methanol	175-183	uncoupling protein 2	Rattus norvegicus	116-126
18816528-1	2008	Bioassay-guided fractionation of MeOH extract from fenugreek (Trigonella foenum-graecum L.) seeds resulted in the isolation of two rat growth-hormone release stimulators in vitro, fenugreek saponin I (1) and dioscin (9), along with two new, i.e., 2 and 3, and five known analogues, i.e., 4-8.	Methanol	33-37	gonadotropin releasing hormone receptor	Rattus norvegicus	135-149
18514176-5	2008	The highest production of R-DmAChE in shake-flask culture after 5-day induction by methanol was 718.50 units/mL, which was about three times higher than our previous expression level of native DmAChE gene in P. pastoris.	Methanol	83-91	Acetylcholine esterase	Drosophila melanogaster	28-34
18514176-5	2008	The highest production of R-DmAChE in shake-flask culture after 5-day induction by methanol was 718.50 units/mL, which was about three times higher than our previous expression level of native DmAChE gene in P. pastoris.	Methanol	83-91	Acetylcholine esterase	Drosophila melanogaster	193-199
18756103-2	2008	A methanol extract of nuruk (NE) attenuated lipopolysaccharide (LPS)- induced nitrite and interleukin (IL)-6 in RAW 264.7 cells.	Methanol	2-10	interleukin 6	Mus musculus	90-108
18495240-1	2008	Effects of sodium dodecyl sulfate, dodecyltrimethylammonium bromide, sodium chloride, sodium sulfate, methanol and ethanol, on the structure and activity of adenosine deaminase (ADA) were investigated by UV-Vis, circular dichroism spectrophotometry and molecular dynamics (MDs) studies.	Methanol	102-110	adenosine deaminase	Homo sapiens	157-176
18495240-1	2008	Effects of sodium dodecyl sulfate, dodecyltrimethylammonium bromide, sodium chloride, sodium sulfate, methanol and ethanol, on the structure and activity of adenosine deaminase (ADA) were investigated by UV-Vis, circular dichroism spectrophotometry and molecular dynamics (MDs) studies.	Methanol	102-110	adenosine deaminase	Homo sapiens	178-181
18584980-4	2008	In the present study we have demonstrated that methanol-aqueous fraction (MAF2) of Cajanus cajan leaf extract could prevent the chronically treated alcohol induced rat liver damage.	Methanol	47-55	MAF bZIP transcription factor	Rattus norvegicus	74-78
18374552-8	2008	In methanol solution, pantoprazole was completely degraded after 120 min and presented zero-order kinetics with t1/2 of 6.48 min.	Methanol	3-11	interleukin 1 receptor like 1	Homo sapiens	112-124
18613199-3	2008	MP2/aug-cc-pVDZ calculations indicate that G-MeOH-1 is the most stable complex among the five optimized structures.	Methanol	45-49	tryptase pseudogene 1	Homo sapiens	0-3
18613199-6	2008	The identity of HK-MeOH-1 is confirmed by both FTIR spectroscopy and MP2/aug-cc-pVDZ calculations.	Methanol	19-23	tryptase pseudogene 1	Homo sapiens	69-72
18636720-6	2008	The nu(OH) bands of methanol measured in the CCl4 solution and pure liquid have been successfully analyzed by the method proposed here.	Methanol	20-28	C-C motif chemokine ligand 4	Homo sapiens	45-49
18546149-0	2008	Methanol extract of Ficus leaf inhibits the production of nitric oxide and proinflammatory cytokines in LPS-stimulated microglia via the MAPK pathway.	Methanol	0-8	mitogen-activated protein kinase 1	Mus musculus	137-141
18998555-5	2008	After induction by methanol, ADPN was expressed in GS115, then the protein was identified by Western blotting.	Methanol	19-27	adiponectin, C1Q and collagen domain containing	Homo sapiens	29-33
18481153-3	2008	Aminooxy-functionalized Affibody (Anti-HER2-ONH2) was incubated with 4-[18F]fluorobenzaldehyde in ammonium acetate buffer at pH 4 in the presence of methanol at 70 degrees C for 15 min.	Methanol	149-157	erb-b2 receptor tyrosine kinase 2	Homo sapiens	39-43
18563235-1	2008	The electrocatalytic activities and mechanisms of PtPb and PtBi ordered intermetallic phases towards formic acid, formaldehyde and methanol oxidation have been studied by DEMS and FTIRS, and the results compared to those for a pure polycrystalline platinum electrode.	Methanol	131-139	protein tyrosine phosphatase receptor type B	Homo sapiens	50-54
18563235-6	2008	In contrast, CO(2) is the major product for formaldehyde and methanol oxidation at a PtPb electrode.	Methanol	61-69	protein tyrosine phosphatase receptor type B	Homo sapiens	85-89
18563235-7	2008	The high current efficiency of CO(2) formation for methanol and formaldehyde oxidation at a PtPb electrode can be ascribed to the complete dehydrogenation of formaldehyde and formic acid due to electronic effects.	Methanol	51-59	protein tyrosine phosphatase receptor type B	Homo sapiens	92-96
18504559-2	2008	BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, and BDE-209 were baseline-resolved under isocratic conditions in 92:8 methanol/water (v/v).	Methanol	130-138	homeobox D13	Homo sapiens	0-3
18676263-5	2008	The yeast transformants that harbored the INGAP gene with high copies were selected with the auxotroph medium and G418, followed then by PCR verification of the positive transformants, from which the expression of recombinant human INGAP was induced with methanol as the only carbone source.	Methanol	255-263	regenerating family member 3 alpha	Homo sapiens	42-47
21202483-0	2008	(Amino-acetato-kappaO,N)bis-(quinolin-8-olato-kappaO,N)cobalt(III) methanol solvate.	Methanol	67-75	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	62-65
18676263-5	2008	The yeast transformants that harbored the INGAP gene with high copies were selected with the auxotroph medium and G418, followed then by PCR verification of the positive transformants, from which the expression of recombinant human INGAP was induced with methanol as the only carbone source.	Methanol	255-263	regenerating family member 3 alpha	Homo sapiens	232-237
18389469-1	2008	Methanol extracts of wood from Pinus resinosa were found to be selectively cytotoxic against human lung carcinoma cells, A549 (IC50 41 +/- 6 microg/mL), human colorectal adenocarcinoma cells, DLD-1 (IC50 47 +/- 4 microg/mL) in comparison with healthy cells, WS1 (IC50 130 +/- 11 microg/mL).	Methanol	0-8	paired box 3	Homo sapiens	258-261
18598171-1	2008	As the methanol extract of Myrica bark inhibited the activity of lipase in isolated mouse plasma in vitro, the influence of the extract on this enzyme in the gastrointestinal tube was investigated after oral intake.	Methanol	7-15	lipase, endothelial	Mus musculus	65-71
18400427-6	2008	RESULTS: Firstly, both methanol extract (CO-W-M) and fraction (CO-W-M2) had potent insulin mimic activity on PEPCK expression.	Methanol	23-31	phosphoenolpyruvate carboxykinase 1	Rattus norvegicus	109-114
18410148-3	2008	The upfield carbinol hydrogen signal belongs to the anti whereas the downfield to the syn stereoisomer.	Methanol	12-20	synemin	Homo sapiens	86-89
18440362-1	2008	Microwave-assisted extraction using 1M KOH/methanol (alkaline-MAE) in combination with solid-phase extraction treatment was developed and applied to polycyclic aromatic hydrocarbons (PAHs) in a sediment sample.	Methanol	43-51	solute carrier family 6 member 1	Homo sapiens	62-65
20046762-2	2008	The method was carried out on a Phenomenex RP-C18 column using a mixture of methanol and water (90:10) and detection was done at 262 nm.	Methanol	76-84	RNA polymerase II, I and III subunit H	Homo sapiens	43-49
18522101-4	2008	The present manuscript reports a comparative study of polychromatic UV photolysis of aqueous NO3- containing RH (RH = HCO2-, CH3OH, or C2H5OH) and H2O2 containing CH3OH, all in aerated buffered aqueous solutions.	Methanol	125-130	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
18294946-8	2008	Molecular mass measurement of intact recombinant NTS1 was performed using a mixture of chloroform/methanol/aqueous trifluoroacetic acid as the mobile phase for size exclusion chromatography-ESI-MS analysis.	Methanol	98-106	neurotensin	Homo sapiens	49-53
18567306-4	2008	FB1 + FB2 are removed with methanol and directly determined by reversed-phase LC with MS detection using selected-ion monitoring of 2 characteristic ions in each case.	Methanol	27-35	Protein DEHYDRATION-INDUCED 19 homolog 5	Zea mays	6-9
18208451-6	2008	We tested several derivatives of the A4, A3B and A2B2 structures for their singlet oxygen quantum yields in methanol and in liposomes, using 9,10-dimethyl anthracene (DMA) as a singlet oxygen target.	Methanol	108-116	apolipoprotein B mRNA editing enzyme catalytic subunit 3B	Homo sapiens	41-44
18466700-4	2008	The ferment cell line of the recombinant sCR1 which was chosen by G418 resistance was identified by PCR, After methanol induction, the expressed protein products were verified by SDS-PAGE and Western blot, purified by Ni(2+)-NTA agarose affinity chromatography, and its biologic activity was identified.	Methanol	111-119	SCR1	Saccharomyces cerevisiae S288C	41-45
18466700-6	2008	The recombinant human sCR1 fusion protein was expressed by yeast cells containing pPIC9k-sCR1 induced by methanol.	Methanol	105-113	SCR1	Saccharomyces cerevisiae S288C	22-26
18466700-6	2008	The recombinant human sCR1 fusion protein was expressed by yeast cells containing pPIC9k-sCR1 induced by methanol.	Methanol	105-113	SCR1	Saccharomyces cerevisiae S288C	89-93
18280603-3	2008	The impact of manufacturing parameters (pH, methanol treatment and drug load) was correlated with IGF-I release kinetics using ELISA and potency tests.	Methanol	44-52	insulin like growth factor 1	Homo sapiens	98-103
18518243-1	2008	The single-molecule magnet [Ni(hmp)(MeOH)Cl]4 (hmp denotes the anion of 2-hydroxymethylpyridine and Me denotes methyl) is studied using both density functional theory (DFT) and the DFT+U method, and the results are compared.	Methanol	36-40	inner membrane mitochondrial protein	Homo sapiens	31-34
18518243-1	2008	The single-molecule magnet [Ni(hmp)(MeOH)Cl]4 (hmp denotes the anion of 2-hydroxymethylpyridine and Me denotes methyl) is studied using both density functional theory (DFT) and the DFT+U method, and the results are compared.	Methanol	36-40	inner membrane mitochondrial protein	Homo sapiens	47-50
18280603-4	2008	Methanol treatment induced water insolubility of SF scaffolds, allowed the control of bioactive IGF-I delivery and did not affect IGF-I potency.	Methanol	0-8	insulin like growth factor 1	Homo sapiens	96-101
18191910-1	2008	Activity-guided fractionation of the methanol extract of Vitis vinifera bark led to the isolation of epsilon-viniferin, ampelopcin A, vitisin A and vitisin B. Vitisin A and vitisin B showed a remarkable inhibitory activity against 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase with IC50 value of 42.1 microM and 23.9 microM, respectively.	Methanol	37-45	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Vitis vinifera	231-288
18348198-0	2008	UHV studies of methanol decomposition on mono- and bimetallic CoPd nanoparticles supported on thin alumina films.	Methanol	15-23	COPD	Homo sapiens	62-66
18348198-11	2008	A comparison with the results of methanol decomposition on Co, Pd, and CoPd catalysts in continuous-flow reactors demonstrates that the findings of the present UHV study are relevant for catalytic performance under high-pressure conditions.	Methanol	33-41	COPD	Homo sapiens	71-75
18289520-9	2008	Analysis of cathepsin activities showed that whilst the activity of cathepsin B and D was not affected by 2M DMSO treatment, their activity was lowered when treated with 2M methanol.	Methanol	173-181	cathepsin Ba	Danio rerio	68-79
18371201-2	2008	Production of recombinant proteins in P. pastoris is usually performed by controlling gene expression with the strong AOX1 promoter, which is induced by addition of methanol.	Methanol	165-173	aldehyde oxidase 1	Homo sapiens	118-122
18371201-3	2008	Optimization of processes using the AOX1 promoter in P. pastoris is generally done in bioreactors by fed-batch fermentation with a controlled continuous addition of methanol for avoiding methanol toxification and carbon/energy starvation.	Methanol	165-173	aldehyde oxidase 1	Homo sapiens	36-40
18371201-3	2008	Optimization of processes using the AOX1 promoter in P. pastoris is generally done in bioreactors by fed-batch fermentation with a controlled continuous addition of methanol for avoiding methanol toxification and carbon/energy starvation.	Methanol	187-195	aldehyde oxidase 1	Homo sapiens	36-40
18371201-5	2008	RESULTS: By applying on-line pO2 monitoring we demonstrate that the widely used pulse feeding of methanol results in long phases of methanol exhaustion and consequently low expression of AOX1 controlled genes.	Methanol	97-105	aldehyde oxidase 1	Homo sapiens	187-191
18275184-6	2008	The lifetime tau1 of the S1/ICT state varies only moderately in all ionic liquids studied here ( approximately 40-110 ps), which lies in the range between ethanol (109 ps) and methanol (49 ps).	Methanol	176-184	proteasome 26S subunit, non-ATPase 1	Homo sapiens	25-31
18309400-7	2008	Most electrocatalysts prepared in this way have a high electrocatalytical surface area, up to 90 m(2) g(-1) Pt, and exhibit high catalytic activities toward methanol electrooxidation.	Methanol	157-165	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	102-110
18293991-2	2008	Treatment of 1,7-diamino-5-bromohept-3-yne derivatives with catalytic Pd(PPh3)4 in the presence of NaH in MeOH gives the 2,7-diazabicyclo[4.3.0]non-5-enes in good yields.	Methanol	106-110	caveolin 1	Homo sapiens	73-77
18409044-1	2008	In our ongoing search for anti-inflammatory agents originating from Korean medicinal plants, we found that the hexane and BuOH fractions of the MeOH extract from the whole plants of Melandrium firmum Rohrbach inhibited 5-lipoxygenase (5-LOX) activity.	Methanol	144-148	arachidonate 5-lipoxygenase	Homo sapiens	219-233
18409044-1	2008	In our ongoing search for anti-inflammatory agents originating from Korean medicinal plants, we found that the hexane and BuOH fractions of the MeOH extract from the whole plants of Melandrium firmum Rohrbach inhibited 5-lipoxygenase (5-LOX) activity.	Methanol	144-148	arachidonate 5-lipoxygenase	Homo sapiens	235-240
17433669-4	2008	The transesterfication of linseed oil in SCF such as methanol and ethanol has proved to be the most promising process.	Methanol	53-61	KIT ligand	Homo sapiens	41-44
17629398-9	2008	Furthermore, the increase of NO3-, NO2-, CH3OH and humic acid would result in the decrease of the degradation values.	Methanol	41-46	NBL1, DAN family BMP antagonist	Homo sapiens	29-32
18203863-0	2008	Trm1p, a Zn(II)2Cys6-type transcription factor, is a master regulator of methanol-specific gene activation in the methylotrophic yeast Candida boidinii.	Methanol	73-81	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	0-5
18203863-2	2008	In this study, we describe a novel gene, TRM1, in Candida boidinii, responsible for the transcriptional activation of several methanol-inducible promoters.	Methanol	126-134	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	41-45
18203863-4	2008	Deletion of TRM1 completely inhibits growth on methanol but causes no growth defect on glucose or other nonfermentative carbon sources, glycerol, ethanol, or oleate.	Methanol	47-55	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	12-16
18203863-5	2008	Trm1p is responsible for transcriptional activation of five methanol-inducible promoters tested, but not for peroxisome assembly or peroxisomal protein transport.	Methanol	60-68	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	0-5
18203863-7	2008	Two cis-acting methanol response elements (MREs), MRE1 and MRE2 are present in the promoter of the dihydroxyacetone synthase gene.	Methanol	15-23	Nam8p	Saccharomyces cerevisiae S288C	59-63
18203863-8	2008	Trm1p is shown to be required for MRE1-dependent methanol-inducible gene expression.	Methanol	49-57	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	0-5
18203863-9	2008	Chromatin immunoprecipitation assays reveal that Trm1p binds to five methanol-inducible promoters upon methanol induction but does not bind in glucose-grown cells.	Methanol	69-77	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	49-54
18203863-9	2008	Chromatin immunoprecipitation assays reveal that Trm1p binds to five methanol-inducible promoters upon methanol induction but does not bind in glucose-grown cells.	Methanol	103-111	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	49-54
18203863-10	2008	Thus, the TRM1 gene encodes a master transcriptional regulator responsible for methanol-specific gene activation in the methylotrophic yeasts.	Methanol	79-87	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	10-14
18288452-0	2008	Glial fibrillary acidic protein (GFAP) and CD34 expression in the human optic nerve and brain in methanol toxicity.	Methanol	97-105	glial fibrillary acidic protein	Homo sapiens	0-31
18288452-11	2008	CD34 expression was markedly decreased by the toxic effects of methanol.	Methanol	63-71	CD34 molecule	Homo sapiens	0-4
18173267-3	2008	The reaction of [Mn3O(O2CMe)6(py)3](ClO4) with 3 equiv of dapdoH2 (with or without 2 equiv of NEt3) in MeOH gave 1.	Methanol	103-107	tetraspanin 2	Homo sapiens	94-98
18173267-4	2008	The same cation, but with a [Ca(NO3)4]2- anion, was found in complex 2, which was obtained from the reaction in MeOH between Mn(NO3)2, Ca(NO3)2, and dapdoH2 in the presence of NEt3.	Methanol	112-116	tetraspanin 2	Homo sapiens	176-180
18173267-5	2008	In contrast, addition of NaN3 to several reactions comprising MnCl2, dapdoH2, and NEt3 in MeOH gave the octanuclear complex 3.	Methanol	90-94	tetraspanin 2	Homo sapiens	82-86
18288452-0	2008	Glial fibrillary acidic protein (GFAP) and CD34 expression in the human optic nerve and brain in methanol toxicity.	Methanol	97-105	glial fibrillary acidic protein	Homo sapiens	33-37
18288452-0	2008	Glial fibrillary acidic protein (GFAP) and CD34 expression in the human optic nerve and brain in methanol toxicity.	Methanol	97-105	CD34 molecule	Homo sapiens	43-47
18288452-6	2008	RESULTS: There was a positive correlation between the GFAP and CD34 intensity of staining scores in the methanol-exposed group (P=0.711, P=0.010).	Methanol	104-112	glial fibrillary acidic protein	Homo sapiens	54-58
18288452-6	2008	RESULTS: There was a positive correlation between the GFAP and CD34 intensity of staining scores in the methanol-exposed group (P=0.711, P=0.010).	Methanol	104-112	CD34 molecule	Homo sapiens	63-67
18288452-7	2008	Furthermore, there was also a positive correlation between the brain putamen and optic nerve head GFAP extent of staining in the methanol-exposed group (P=0.720, P=0.008).	Methanol	129-137	glial fibrillary acidic protein	Homo sapiens	98-102
18288452-8	2008	A statistically significant difference was found between the methanol-exposed group and the control group optic nerve CD34 intensity scores (P=0.014), but no significant difference was found between optic nerve CD34 and GFAP extent scores (P=0.05).	Methanol	61-69	CD34 molecule	Homo sapiens	118-122
18309571-3	2008	Expression of hGMCSF was done using glycerol and methanol based synthetic medium by three stage cultivation in a bioreactor.	Methanol	49-57	colony stimulating factor 2	Homo sapiens	14-20
18171033-0	2008	Bond dissociation energies and equilibrium structures of Cu+(MeOH)x, x = 1-6, in the gas phase: competition between solvation of the metal ion and hydrogen-bonding interactions.	Methanol	61-65	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	69-76
17949767-4	2008	Subsequent reverse-phase high-performance liquid chromatography (RP-HPLC) of the dichloromethane/methanol (1/1) fraction separated contaminants potent in the TR and Luc assays from those potent in the TTR assay.	Methanol	97-105	transthyretin L homeolog	Xenopus laevis	201-204
18179197-7	2008	Solvent induced aggregation studies of polymers in THF and methanol mixture further supports the existence of strong aggregation in MEH-PPV as compared to that of bulky BTCD-60.	Methanol	59-67	epoxide hydrolase 1	Homo sapiens	132-135
18171033-1	2008	The solvation of Cu+ by methanol (MeOH) was studied via examination of the kinetic energy dependence of the collision-induced dissociation of Cu+(MeOH)x complexes, where x = 1-6, with Xe in a guided ion beam tandem mass spectrometer.	Methanol	24-32	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	170-177
18171033-1	2008	The solvation of Cu+ by methanol (MeOH) was studied via examination of the kinetic energy dependence of the collision-induced dissociation of Cu+(MeOH)x complexes, where x = 1-6, with Xe in a guided ion beam tandem mass spectrometer.	Methanol	34-38	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	170-177
18171033-1	2008	The solvation of Cu+ by methanol (MeOH) was studied via examination of the kinetic energy dependence of the collision-induced dissociation of Cu+(MeOH)x complexes, where x = 1-6, with Xe in a guided ion beam tandem mass spectrometer.	Methanol	146-150	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	170-177
18097493-5	2008	Interestingly, 1b.MeOH undergoes facile metal-centred oxidation by aerial O2-H2O2-[Fe(eta5-C5H5)2][PF6], which led to the isolation of the corresponding cobalt(iii) complex [CoIII(L2)][ClO4] (2b).	Methanol	18-22	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	174-179
17997062-4	2008	AIM OF THE STUDY: To determine whether a methanol extract of Theobroma cacao L. (Sterculiaceae) beans enriched for polyphenols could inhibit CGRP expression, both an in vitro and an in vivo approach was taken.	Methanol	41-49	calcitonin-related polypeptide alpha	Rattus norvegicus	141-145
18029185-1	2008	The methanol extract from Selaginella tamariscina significantly inhibited UV irradiation induced activity of matrix metalloproteinase-1 (MMP-1) in primary fibroblasts from human skin.	Methanol	4-12	matrix metallopeptidase 1	Homo sapiens	137-142
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	109-114
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	156-161
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	109-114
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	109-113
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	156-160
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	104-107
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	109-112
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	156-161
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	109-113
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	156-160
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	104-107
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	175-179	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	109-112
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	109-114
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	156-161
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	109-113
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	156-160
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	104-107
18097493-11	2008	Cyclic voltammetry experiments in MeCN-CH2Cl2 reveal facile metal-centred reversible-to-quasireversible CoIV-CoIII (or a ligand-centred redox process; 2a), CoIII-CoII (1a, 1b.MeOH, 2a, 2b and 3), CoII-CoI (1a, 1b.MeOH, 2aand 2b), and CoI-Co0 (1a, 1b.MeOH and 2b) redox processes.	Methanol	213-217	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	109-112
18052384-4	2008	Our calculated relative activation barriers of the SN2 reaction in methanol, tert-butyl alcohol, and CH3CN are in good agreement with experimental observations.	Methanol	67-75	solute carrier family 38 member 5	Homo sapiens	51-54
18711775-3	2008	The MeOH extract and EtOAc fraction were found to exhibit potent rat lens aldose reductase inhibition in vitro, their IC(50) being 1.2 and 0.6 microg/ml, respectively.	Methanol	4-8	aldo-keto reductase family 1 member B1	Rattus norvegicus	74-90
17909812-4	2008	METHODS: FTS was isolated from mouse plasma by liquid chromatography on a Columbus 5-mum particle size, 50 x 2 mm id column with a methanol/5 mM ammonium acetate (80/20) mobile phase (isocratic elution) at a flow rate of 0.3 ml/min.	Methanol	131-139	AKT interacting protein	Mus musculus	9-12
18175960-1	2008	Our previous studies reported that methanol extract of Sanguisorbae radix from Sanguisorba officinalis L. (Rosaceae) prevented neuronal cell damage induced by Abeta (25-35) in vitro.	Methanol	35-43	amyloid beta precursor protein	Rattus norvegicus	159-164
17803200-5	2008	Our data show that deletion of Met1 and Val17 from this hairpin destabilized the folded state in both aqueous solution and in aqueous-methanol solutions.	Methanol	134-142	granzyme M	Homo sapiens	31-35
18022966-4	2008	In [Fe(II)(PrL1)(2)](BPh(4))(2) (3) the ligand is facially coordinated to the metal with an N,N,O donor set, whereas in [Fe(II)(PrL1)(2)(MeOH)(2)](OTf)(2) (4) a bidentate N,N binding mode is found.	Methanol	137-141	protein tyrosine phosphatase 4A1	Homo sapiens	11-15
18942701-3	2008	Reaction of the bpiH protio-ligands with a twofold excess of cobalt(II) acetate or cobalt(II) acetylacetonate in methanol gave [Co(bpi)(OAc)], which crystallize as coordination polymers, and a series of [Co(acac)(bpi)(MeOH)], which are mononuclear octahedral complexes.	Methanol	113-121	bactericidal permeability increasing protein	Homo sapiens	16-19
22578868-1	2008	Human interferon alpha2b gene was cloned in the methylotrophic yeast Pichia pastoris under the control of the AOX1 methanol inducible promoter.	Methanol	115-123	interferon alpha 2	Homo sapiens	6-24
18942701-3	2008	Reaction of the bpiH protio-ligands with a twofold excess of cobalt(II) acetate or cobalt(II) acetylacetonate in methanol gave [Co(bpi)(OAc)], which crystallize as coordination polymers, and a series of [Co(acac)(bpi)(MeOH)], which are mononuclear octahedral complexes.	Methanol	113-121	bactericidal permeability increasing protein	Homo sapiens	131-134
18942701-3	2008	Reaction of the bpiH protio-ligands with a twofold excess of cobalt(II) acetate or cobalt(II) acetylacetonate in methanol gave [Co(bpi)(OAc)], which crystallize as coordination polymers, and a series of [Co(acac)(bpi)(MeOH)], which are mononuclear octahedral complexes.	Methanol	218-223	bactericidal permeability increasing protein	Homo sapiens	16-19
18942701-3	2008	Reaction of the bpiH protio-ligands with a twofold excess of cobalt(II) acetate or cobalt(II) acetylacetonate in methanol gave [Co(bpi)(OAc)], which crystallize as coordination polymers, and a series of [Co(acac)(bpi)(MeOH)], which are mononuclear octahedral complexes.	Methanol	218-223	bactericidal permeability increasing protein	Homo sapiens	131-134
18942701-4	2008	Upon heating the [Co(acac)(bpi)(MeOH)] compounds to 100 degrees C under high vacuum, the coordinated methanol was removed to give the five-coordinate complexes [Co(acac)(bpi)].	Methanol	32-37	bactericidal permeability increasing protein	Homo sapiens	27-30
18942701-4	2008	Upon heating the [Co(acac)(bpi)(MeOH)] compounds to 100 degrees C under high vacuum, the coordinated methanol was removed to give the five-coordinate complexes [Co(acac)(bpi)].	Methanol	32-37	bactericidal permeability increasing protein	Homo sapiens	170-173
18942701-4	2008	Upon heating the [Co(acac)(bpi)(MeOH)] compounds to 100 degrees C under high vacuum, the coordinated methanol was removed to give the five-coordinate complexes [Co(acac)(bpi)].	Methanol	101-109	bactericidal permeability increasing protein	Homo sapiens	27-30
18942701-4	2008	Upon heating the [Co(acac)(bpi)(MeOH)] compounds to 100 degrees C under high vacuum, the coordinated methanol was removed to give the five-coordinate complexes [Co(acac)(bpi)].	Methanol	101-109	bactericidal permeability increasing protein	Homo sapiens	170-173
18173719-2	2008	The resulting water-soluble octadiazopyruvoyl PAMAM (8G.1 DAP, 1.3) was shown to undergo Wolff rearrangements upon photolysis in methanol at lambda &gt; 300 nm to yield the methyl esters of the ketenes formed from the loss of nitrogen.	Methanol	129-137	death associated protein	Homo sapiens	58-61
18181245-5	2008	With increasing methanol, at pH near neutrality, apo-CRBP exhibits a progressively more compact conformation, resulting in reduced H/D exchange with respect to the native protein in water.	Methanol	16-24	retinol binding protein 1	Homo sapiens	53-57
19029788-3	2008	In LC separation, Cadenza CD-C18 and 10 mmol/L ammonium acetate-methanol were used as the column and mobile phase, respectively.	Methanol	64-72	septin 7	Homo sapiens	26-39
18034701-2	2007	Because ethanol is preferentially metabolized over methanol (MeOH) by alcohol dehydrogenase, it is not surprising that MeOH accumulates in the alcohol-abusing population.	Methanol	51-59	aldo-keto reductase family 1 member A1	Rattus norvegicus	70-91
18052210-3	2007	Methanol-induced expression of alpha2 is optimal at 20 degrees C, whereas at 25 degrees C, which is optimal for expression of alpha1, alpha2 is not expressed.	Methanol	0-8	adrenoceptor alpha 1D	Homo sapiens	126-132
18020339-3	2007	From a methanol solution of M(acac)3, H(4)1, S-nicI, and KOH, the delta delta delta delta-KH3(S-nic)7[(S-nic) subset M(4)1(6)] complexes precipitate, and the lambda lambda lambda lambda-K6(S-nic)5[(S-nic) subset M(4)1(6)] complexes subsequently can be isolated from the supernatant.	Methanol	7-15	CDV3 homolog	Homo sapiens	28-43
18034701-2	2007	Because ethanol is preferentially metabolized over methanol (MeOH) by alcohol dehydrogenase, it is not surprising that MeOH accumulates in the alcohol-abusing population.	Methanol	61-65	aldo-keto reductase family 1 member A1	Rattus norvegicus	70-91
18034701-2	2007	Because ethanol is preferentially metabolized over methanol (MeOH) by alcohol dehydrogenase, it is not surprising that MeOH accumulates in the alcohol-abusing population.	Methanol	119-123	aldo-keto reductase family 1 member A1	Rattus norvegicus	70-91
18047795-2	2007	The MeOH extract and the n-hexane (HX) fraction of GR induced rat GH (rGH) release up to 1.89 times (0.34 +/- 0.04 nM) and 4.59 times (0.83 +/- 0.03 nM), compared to the basal level (p &lt; 0.05).	Methanol	4-8	gonadotropin releasing hormone receptor	Rattus norvegicus	66-68
17921299-9	2007	Mutation of this gene in the triple-FDH mutant background resulted in a methanol-negative phenotype.	Methanol	72-80	MEXAM1_RS01440	Methylobacterium extorquens AM1	36-39
17639563-4	2007	The methanol extract was most active in both assays with IC(50) values of 12 microg/mL for COX-1 and 19 microg/mL for COX-2.	Methanol	4-12	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	91-96
17639563-4	2007	The methanol extract was most active in both assays with IC(50) values of 12 microg/mL for COX-1 and 19 microg/mL for COX-2.	Methanol	4-12	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	118-123
17634866-2	2007	A hydrophobic ionic liquid thus protects the lipase from methanol.	Methanol	57-65	PAN0_003d1715	Moesziomyces antarcticus	45-51
17673349-6	2007	Asp, Phe or MeOH concentrations related to their CSF levels after ingestion of abuse or toxic ASP doses, when separately incubated with frontal cortex or pure AChE, resulted in a significant decrease of the enzyme activities.	Methanol	12-16	colony stimulating factor 2	Rattus norvegicus	49-52
17673349-6	2007	Asp, Phe or MeOH concentrations related to their CSF levels after ingestion of abuse or toxic ASP doses, when separately incubated with frontal cortex or pure AChE, resulted in a significant decrease of the enzyme activities.	Methanol	12-16	acetylcholinesterase	Rattus norvegicus	159-163
18047799-4	2007	The 70% methanol extract of DR, and its n-hexane and n-BuOH fractions, induced rat GH (rGH) release in rat pituitary cells 10-fold, 8-fold, and 5- fold higher than the control (0.36 +/- 0.02 nM), respectively (p &lt; 0.05 each).	Methanol	8-16	gonadotropin releasing hormone receptor	Rattus norvegicus	83-85
19073120-2	2007	Bromhexine in methanol/0.1molL(-1) Britton-Robinson buffer solution (2.5/97.5) shows an anodic response on glassy carbon electrode between pH 2 and 7.5.	Methanol	14-22	polyhomeotic homolog 2	Homo sapiens	139-143
18066112-10	2007	Our data indicate that both the aqueous and methanol extracts of all 5 uva-ursi products showed high cytochrome P450 isozyme inhibition, with the exception of the methanol extracts against cytochromes P3A4 and P19, which had low to moderate activity.	Methanol	44-52	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	101-116
17847018-1	2007	The present work is a combined structural study, using Nuclear Magnetic Resonance (NMR) and Molecular Dynamics(MD), of the amidated and the free acid forms of substance P in water and methanol.	Methanol	184-192	tachykinin precursor 1	Homo sapiens	159-170
17661331-0	2007	Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum.	Methanol	90-98	tyrosinase	Homo sapiens	0-10
17709370-14	2007	Methanol and acetonitrile at concentrations of &lt; or =0.5% and &lt; or =1% (v/v) appeared to be suitable for the measurement of CYP2B6- and CYP2C8-mediated activities, respectively.	Methanol	0-8	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	130-136
17709370-14	2007	Methanol and acetonitrile at concentrations of &lt; or =0.5% and &lt; or =1% (v/v) appeared to be suitable for the measurement of CYP2B6- and CYP2C8-mediated activities, respectively.	Methanol	0-8	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	142-148
18181330-10	2007	RESULTS: At the concentrations 50 and 100 ig/mL, the methanol extract of Myristica fragrans Houtt significantly inhibited Jurkat cell proliferation and induced apoptosis as detected by annexin V staining.	Methanol	53-61	annexin A5	Homo sapiens	185-194
18181330-11	2007	Downregulation of SIRT1 mRNA expression in Jurkat cells was observed even when the amount of methanol extract was 10 microg/mL.	Methanol	93-101	sirtuin 1	Homo sapiens	18-23
17553737-1	2007	Ten novel macrocyclic Co(II) compounds have been synthesized by treating four N(4) and six N(2)O(2) donor macrocycles with cobalt chloride in methanol.	Methanol	142-150	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	22-28
17900185-2	2007	The relatively labile [Ru(NO)(bpym)(terpy)](3+), which forms a structurally characterized acetonitrile substitution product [Ru(CH3CN)(bpym)(terpy)](PF6)2 upon treatment with CH3OH/CH3CN, is electrochemically reduced in three one-electron steps of which the third, leading to neutral [Ru(NO)(bpym)(terpy)], involves electrode adsorption.	Methanol	175-180	sperm associated antigen 17	Homo sapiens	149-152
17900114-5	2007	DFT calculations identify the steps needed to form the carboxylate from imidazole and DMC: SN2 methyl transfer from DMC to imidazole, followed by proton transfer from the imidazolium CH to the carboxylate counterion, produces the free NHC H-bonded to MeOH with a weakly associated CO2.	Methanol	251-255	high mobility group nucleosomal binding domain 4	Homo sapiens	235-238
17517049-8	2007	CONCLUSION: Taken together, the results indicate that CYP2C9 is the major contributor to Gz metabolic clearance, although CYP2C19 may also be involved in MeOH-Gz formation (the major metabolic pathway).	Methanol	154-158	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	122-129
32900120-1	2007	The self-assembly of a hydrophobically modified fragment of the amyloid beta (Abeta) peptide has been studied in methanol.	Methanol	113-121	amyloid beta precursor protein	Homo sapiens	78-83
17602542-3	2007	In each IR-PD spectrum, a single peak was observed at a wavenumber lower by approximately 40 cm-1 than that of the OH stretching vibration of a free methanol molecule and was assigned to the OH stretching vibrations of the methanol molecules in Ni3,4+ (CH3OH)m. The photodissociation was analyzed by assuming that Ni3,4+ (CH3OH)m dissociate unimolecularly after the photon energy absorbed by them is statistically distributed among the accessible modes of Ni3,4+ (CH3OH)m. In comparison with the calculations performed by the density functional theory, it is concluded that (1) the oxygen atom of each methanol molecule is bound to one of the nickel atoms in Ni3,4+ (defined as molecular chemisorption), (2) the methanol molecules in Ni3,4+ (CH3OH)m do not form any hydrogen bonds, and (3) the cross section for demethanation [CH4 detachment from Nin+ (CH3OH)] is related to the electron density distribution inside the methanol molecule.	Methanol	223-231	ninein	Homo sapiens	847-850
18043650-0	2007	Stable-isotope probing implicates Methylophaga spp and novel Gammaproteobacteria in marine methanol and methylamine metabolism.	Methanol	91-99	histocompatibility minor 13	Homo sapiens	47-50
17639527-0	2007	In-situ flow-cell IRAS observation of intermediates during methanol oxidation on low-index platinum surfaces.	Methanol	59-67	nischarin	Homo sapiens	18-22
17628631-0	2007	Mineralization of CCl4 by the UVC-photolysis of hydrogen peroxide in the presence of methanol.	Methanol	85-93	C-C motif chemokine ligand 4	Homo sapiens	18-22
17628631-2	2007	The UVC-photolysis (254 nm) of H2O2 added to aqueous solutions of CCl4 is leading to the homolysis of the oxidant yielding hydroxyl radicals (HO) that subsequently react with added methanol to generate hydroxymethyl radicals (CH2OH).	Methanol	181-189	C-C motif chemokine ligand 4	Homo sapiens	66-70
17628631-5	2007	Carbon dioxide radical anion, CO2(-), an intermediate in the mineralization pathway of methanol, is also shown to initiate the mineralization of CCl4 by reductive dechlorination.	Methanol	87-95	C-C motif chemokine ligand 4	Homo sapiens	145-149
17316367-3	2007	Hence, Pyc1p-deficient cells share aspartate auxotrophy (Asp-) with a defect in growth on methanol as sole carbon source (Mut-).	Methanol	90-98	pyruvate carboxylase 1	Saccharomyces cerevisiae S288C	7-12
17728215-9	2007	In vitro, expression of OGR1, but not GPR4, inhibited cell migration (mean percentage of cells migrated, 30.2% versus 100%, difference = 69.8%, 95% CI = 63.0% to 75.9%; P&lt;.001) via increased expression of G alpha(i1) and the secretion of a chloroform/methanol-extractable heat-insensitive factor into the conditioned medium through a PTX-sensitive pathway.	Methanol	254-262	G protein-coupled receptor 68	Mus musculus	24-28
18074804-1	2007	Experiments on Wistar rats showed that acute poisoning with methanol (0.75 LD50) leads to the suppression of cellular and humoral immune responses and decreases the blood concentration of interleukins (IL-2, IL-4) with an increase in the IL-2/IL-4 ratio.	Methanol	60-68	interleukin 2	Rattus norvegicus	202-206
18074804-1	2007	Experiments on Wistar rats showed that acute poisoning with methanol (0.75 LD50) leads to the suppression of cellular and humoral immune responses and decreases the blood concentration of interleukins (IL-2, IL-4) with an increase in the IL-2/IL-4 ratio.	Methanol	60-68	interleukin 4	Rattus norvegicus	208-212
18074804-1	2007	Experiments on Wistar rats showed that acute poisoning with methanol (0.75 LD50) leads to the suppression of cellular and humoral immune responses and decreases the blood concentration of interleukins (IL-2, IL-4) with an increase in the IL-2/IL-4 ratio.	Methanol	60-68	interleukin 2	Rattus norvegicus	238-242
18074804-1	2007	Experiments on Wistar rats showed that acute poisoning with methanol (0.75 LD50) leads to the suppression of cellular and humoral immune responses and decreases the blood concentration of interleukins (IL-2, IL-4) with an increase in the IL-2/IL-4 ratio.	Methanol	60-68	interleukin 4	Rattus norvegicus	243-247
17590357-6	2007	Water-soluble organic (co)solvents inhibited hERG K(+) currents (IC(20), %/mM): 0.7/152, ethanol; 0.9/67, Transcutol; 1.2/154, DMSO (dimethylsulfoxide); 1.6/389, acetonitrile; 1.9/48, polyethylene glycol 400; 2.1/660, methanol.	Methanol	218-226	ETS transcription factor ERG	Homo sapiens	45-49
17676879-4	2007	Aggregation of a poly(phenylene ethynylene)-type CPE (PPE-CO2-) is induced by the addition of either water or Ca2+ to methanol solution, as indicated by absorption, fluorescence, dynamic light scattering, and fluorescence microscope measurements.	Methanol	118-126	carboxypeptidase E	Homo sapiens	49-52
17602542-3	2007	In each IR-PD spectrum, a single peak was observed at a wavenumber lower by approximately 40 cm-1 than that of the OH stretching vibration of a free methanol molecule and was assigned to the OH stretching vibrations of the methanol molecules in Ni3,4+ (CH3OH)m. The photodissociation was analyzed by assuming that Ni3,4+ (CH3OH)m dissociate unimolecularly after the photon energy absorbed by them is statistically distributed among the accessible modes of Ni3,4+ (CH3OH)m. In comparison with the calculations performed by the density functional theory, it is concluded that (1) the oxygen atom of each methanol molecule is bound to one of the nickel atoms in Ni3,4+ (defined as molecular chemisorption), (2) the methanol molecules in Ni3,4+ (CH3OH)m do not form any hydrogen bonds, and (3) the cross section for demethanation [CH4 detachment from Nin+ (CH3OH)] is related to the electron density distribution inside the methanol molecule.	Methanol	223-231	ninein	Homo sapiens	847-850
17602542-3	2007	In each IR-PD spectrum, a single peak was observed at a wavenumber lower by approximately 40 cm-1 than that of the OH stretching vibration of a free methanol molecule and was assigned to the OH stretching vibrations of the methanol molecules in Ni3,4+ (CH3OH)m. The photodissociation was analyzed by assuming that Ni3,4+ (CH3OH)m dissociate unimolecularly after the photon energy absorbed by them is statistically distributed among the accessible modes of Ni3,4+ (CH3OH)m. In comparison with the calculations performed by the density functional theory, it is concluded that (1) the oxygen atom of each methanol molecule is bound to one of the nickel atoms in Ni3,4+ (defined as molecular chemisorption), (2) the methanol molecules in Ni3,4+ (CH3OH)m do not form any hydrogen bonds, and (3) the cross section for demethanation [CH4 detachment from Nin+ (CH3OH)] is related to the electron density distribution inside the methanol molecule.	Methanol	223-231	ninein	Homo sapiens	847-850
17602542-3	2007	In each IR-PD spectrum, a single peak was observed at a wavenumber lower by approximately 40 cm-1 than that of the OH stretching vibration of a free methanol molecule and was assigned to the OH stretching vibrations of the methanol molecules in Ni3,4+ (CH3OH)m. The photodissociation was analyzed by assuming that Ni3,4+ (CH3OH)m dissociate unimolecularly after the photon energy absorbed by them is statistically distributed among the accessible modes of Ni3,4+ (CH3OH)m. In comparison with the calculations performed by the density functional theory, it is concluded that (1) the oxygen atom of each methanol molecule is bound to one of the nickel atoms in Ni3,4+ (defined as molecular chemisorption), (2) the methanol molecules in Ni3,4+ (CH3OH)m do not form any hydrogen bonds, and (3) the cross section for demethanation [CH4 detachment from Nin+ (CH3OH)] is related to the electron density distribution inside the methanol molecule.	Methanol	223-231	ninein	Homo sapiens	847-850
17580119-7	2007	Methanol concentrations of 0.60 or 0.80mM remarkably inhibited hippocampal AChE by about 18 and 22% and pure enzyme by about 14 and 20%, respectively.	Methanol	0-8	acetylcholinesterase	Rattus norvegicus	75-79
17847706-4	2007	By hindering the approach of substrate and the exit of products, methanol and ethanol decrease cholinesterase activity at low substrate concentrations and allow for the substrate inhibition only at higher substrate concentrations.	Methanol	65-73	butyrylcholinesterase	Equus caballus	95-109
17482479-3	2007	We report the P53 expression by the methylotrophic yeast Pichia pastoris using the methanol inducible AOX1 promoter.	Methanol	83-91	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	14-17
17499198-0	2007	Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex.	Methanol	98-106	nitric oxide synthase 2, inducible	Mus musculus	48-52
17566991-1	2007	The structure of the phenol dimer and phenol...methanol complexes was determined by gradient optimization using the Hartree-Fock (HF), MP2, DFT, and RI-DFT-D methods with various basis sets.	Methanol	47-55	tryptase pseudogene 1	Homo sapiens	135-138
17499198-0	2007	Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex.	Methanol	98-106	tumor necrosis factor	Mus musculus	57-66
17499198-3	2007	The methanol extract of PC (PC extract) attenuated LPS-stimulated increase in production of TNF-alpha, IL-1beta, and NO in BV2 cells, a mouse microglia cell line, as well as in primary mouse microglia.	Methanol	4-12	tumor necrosis factor	Mus musculus	92-101
17499198-3	2007	The methanol extract of PC (PC extract) attenuated LPS-stimulated increase in production of TNF-alpha, IL-1beta, and NO in BV2 cells, a mouse microglia cell line, as well as in primary mouse microglia.	Methanol	4-12	interleukin 1 beta	Mus musculus	103-111
17822030-2	2007	The 67LR protein was expressed in Pichia pastoris after induced by methanol, and about 12.56 mg electrophoresis purity 67LR could be obtained after the purification of 1L culture using affinity chromatograph column.	Methanol	67-75	ribosomal protein SA	Homo sapiens	4-8
17520116-1	2007	Single nanogram amounts of the explosives TNT, RDX, HMX, PETN and their mixtures were detected and identified in a few seconds on the surface of human skin without any sample preparation by desorption electrospray ionization (DESI) using a spray solution of methanol-water doped with sodium chloride to form the chloride adducts with RDX, HMX, and PETN while TNT was examined as the radical anion and tandem mass spectrometry was used to confirm the identifications.	Methanol	258-266	chromosome 16 open reading frame 82	Homo sapiens	42-45
17646715-0	2007	Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-kappaB transactivation in LPS-activated RAW 264.7 cells.	Methanol	0-8	prostaglandin-endoperoxide synthase 2	Mus musculus	47-63
17646715-0	2007	Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-kappaB transactivation in LPS-activated RAW 264.7 cells.	Methanol	0-8	prostaglandin-endoperoxide synthase 2	Mus musculus	65-70
17646715-0	2007	Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-kappaB transactivation in LPS-activated RAW 264.7 cells.	Methanol	0-8	nitric oxide synthase 2, inducible	Mus musculus	76-107
17646715-0	2007	Methanol extracts of Stewartia koreana inhibit cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) gene expression by blocking NF-kappaB transactivation in LPS-activated RAW 264.7 cells.	Methanol	0-8	nitric oxide synthase 2, inducible	Mus musculus	109-113
17506110-4	2007	A strain with the disrupted PEX5 gene (pex5Delta) lost its ability to grow on peroxisome-inducible carbon sources, methanol and oleate, but grew normally on glucose and glycerol.	Methanol	115-123	Pex5p	Saccharomyces cerevisiae S288C	28-32
17270371-5	2007	Caco-2 cells were treated with methanol extracts from two Curcuma rhizomes (0.1mg/ml) or curcumin (30 microM) for 72 h. Both extracts significantly decreased the activity of CYP3A4 by about 85-98%.	Methanol	31-39	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	174-180
17390126-4	2007	Methanol, at flow rates of 0.48, 1.5, and 2.5 mL min(-1), respectively, was used as mobile phase for isocratic elution of the compounds in the three methods.	Methanol	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	49-55
17461595-9	2007	These results clearly show that C. genistoides methanol extracts display phytoestrogenic activity and act predominantly via ERbeta.	Methanol	47-55	estrogen receptor 2	Homo sapiens	124-130
17630122-3	2007	HAp-deposited SF films were prepared by soaking methanol-treated SF films containing &gt;5 wt% CaCl2 in a simulated body fluid with the ion concentration 1.5-fold higher than that of the standard one.	Methanol	48-56	BAG cochaperone 1	Homo sapiens	0-3
17418512-3	2007	The total methanol extracts of fresh leaves (l-TME) or roots (r-TME) of Codonopsis lanceolata L. significantly suppressed the production of pro-inflammatory mediators (nitric oxide [NO] and tumor necrosis factor [TNF-alpha]) without altering mRNA levels.	Methanol	10-18	T-associated maternal effect	Mus musculus	47-50
17418512-3	2007	The total methanol extracts of fresh leaves (l-TME) or roots (r-TME) of Codonopsis lanceolata L. significantly suppressed the production of pro-inflammatory mediators (nitric oxide [NO] and tumor necrosis factor [TNF-alpha]) without altering mRNA levels.	Methanol	10-18	T-associated maternal effect	Mus musculus	64-67
17094073-1	2007	Immobilized lipase from Candida antarctica (Novozym 435) was employed in the kinetic resolution of racemic flurbiprofen by enantioselective esterification with methanol.	Methanol	160-168	PAN0_003d1715	Moesziomyces antarcticus	12-18
17469873-1	2007	Reaction of aryl- or heteroarylboronic acids with aldehydes, in the presence of PdCl2 and P(1-Nap)3, afforded carbinol derivatives in good to excellent yields.	Methanol	110-118	phosducin like 2	Homo sapiens	80-99
17455918-3	2007	The HO2 and OH yield is obtained by comparison with an established reference mixture, including CH3OH.	Methanol	96-101	heme oxygenase 2	Homo sapiens	4-7
17094073-2	2007	It was found that the lipase has the R-stereopreference and the reaction matches Bi Bi Ping Pong mechanism with dead-end inhibition of methanol.	Methanol	135-143	PAN0_003d1715	Moesziomyces antarcticus	22-28
17196350-5	2007	), a GABA(A)-benzodiazepine receptor antagonist, blocked the effects of ME (300 mg/kg, p.o.)	Methanol	72-74	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	5-12
17338565-1	2007	As part of an ongoing search for plant-derived compounds that inhibit the activation of NF-kappaB, the methanol extract of the aerial parts of Isodon excisus was found to have significant inhibitory effects on the activation of NF-kappaB in murine macrophage RAW264.7 cells.	Methanol	103-111	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	88-97
17399694-10	2007	hsp70 expression was more in FDD+MeOH group when compared to FDD+LPA+MeOH group.	Methanol	33-37	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	0-5
17399694-10	2007	hsp70 expression was more in FDD+MeOH group when compared to FDD+LPA+MeOH group.	Methanol	69-73	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	0-5
17432890-7	2007	The ability of methanol to effectively solubilize and denature both hydrophobic and hydrophilic proteins was demonstrated using bacteriorhodopsin and cytochrome c, respectively, where both proteins were identified with at least 82% sequence coverage from a single reversed-phase LC-MS/MS analysis.	Methanol	15-23	Cytochrome c	Arabidopsis thaliana	150-162
17328541-3	2007	a undergoes an abrupt spin crossover (SCO) at 255 K with a hysteresis loop of 6 K. a.CH3OH, 2a.H2O, and 2b.H2O exhibit irreversible SCO behaviors due to the loss of solvent molecules upon heating.	Methanol	85-90	spindlin 1	Homo sapiens	22-26
17328541-4	2007	3a, 3b, 4a, and 5a.H2O show simple spin transitions above 350 K. The desolvated samples of 4b.CH3OH and 5b.H2O undergo two-step spin transitions.	Methanol	94-99	spindlin 1	Homo sapiens	128-132
17425351-2	2007	In methanol, both PB1 and PB4 were monomeric producing the triplet states and singlet oxygen after excitation.	Methanol	3-11	polybromo 1	Homo sapiens	18-21
17329963-2	2007	Atg26, the enzyme that converts sterol to SG, is essential for degradation of very large methanol-induced peroxisomes, but only partly required for degradation of smaller-sized oleate- and amine-induced peroxisomes in Pichia pastoris.	Methanol	89-97	sterol 3-beta-glucosyltransferase	Saccharomyces cerevisiae S288C	0-5
17338565-1	2007	As part of an ongoing search for plant-derived compounds that inhibit the activation of NF-kappaB, the methanol extract of the aerial parts of Isodon excisus was found to have significant inhibitory effects on the activation of NF-kappaB in murine macrophage RAW264.7 cells.	Methanol	103-111	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	228-237
17292351-1	2007	The methanol (50%) extract of the whole plant was observed to inhibit the expression of inducible nitric oxide synthase (iNOS) and the cycloxygenase-2 (COX-2) gene in lipopolysaccharide (LPS)-induced macrophage cells (J774A.1, [Raghav, S.K., Gupta, B., Agrawal, C., Goswami, K., Das, H.R., 2006b.	Methanol	4-12	nitric oxide synthase 2, inducible	Mus musculus	88-119
17275869-9	2007	The methanol extract (E4) was the only extract that showed a time-, dose-, and estrogen-receptor-dependent stimulation of pS2 gene expression.	Methanol	4-12	estrogen receptor 1	Homo sapiens	79-96
17275869-9	2007	The methanol extract (E4) was the only extract that showed a time-, dose-, and estrogen-receptor-dependent stimulation of pS2 gene expression.	Methanol	4-12	trefoil factor 1	Homo sapiens	122-125
17292351-1	2007	The methanol (50%) extract of the whole plant was observed to inhibit the expression of inducible nitric oxide synthase (iNOS) and the cycloxygenase-2 (COX-2) gene in lipopolysaccharide (LPS)-induced macrophage cells (J774A.1, [Raghav, S.K., Gupta, B., Agrawal, C., Goswami, K., Das, H.R., 2006b.	Methanol	4-12	nitric oxide synthase 2, inducible	Mus musculus	121-125
17309275-2	2007	Pyrene-appended dioxaoctanediamide 1 showed a selective fluorescence quenching toward Hg2+ ions over other transition-metal ions in an aqueous methanol solution.	Methanol	143-151	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	86-89
17343998-1	2007	Methanol and ethanol are primarily metabolized through the alcohol dehydrogenase (ADH) system in adults.	Methanol	0-8	aldo-keto reductase family 1 member A1	Homo sapiens	59-80
17343998-1	2007	Methanol and ethanol are primarily metabolized through the alcohol dehydrogenase (ADH) system in adults.	Methanol	0-8	aldo-keto reductase family 1 member A1	Homo sapiens	82-85
17343998-10	2007	In the perinatal infants, these results suggest that catalase may play a more prominent role in the metabolism of alcohols than does the ADH system and may explain the finding of first-order kinetics in case reports of high methanol and ethanol intoxication.	Methanol	224-232	catalase	Homo sapiens	53-61
17288463-12	2007	Dopants did enhance Kr lamp APPI sensitivity when MeOH was used as the mobile phase.	Methanol	50-54	amyloid beta precursor protein	Homo sapiens	28-32
17274660-1	2007	The Pd(OCOCF3)2/[(HOCH2CH2NHCOCH2)2NCH2]2-catalyzed oxidation of o-allylphenol with H2O2 in water/methanol affords a syn and anti mixture of 2-(1,2-dihydroxypropyl)phenol and 2-(2-hydroxy-1-methoxypropyl)phenol.	Methanol	98-106	synemin	Homo sapiens	117-120
17256929-3	2007	In the presence of the triaza ligand:Zn2+ complex, the change from water to methanol and then to ethanol brings about a mechanism where two molecules of the complex, suggested as EtOH:Zn2+:[12]aneN3 and its basic form, EtO-:Zn2+:[12]aneN3, bind to HPNPP and catalyze its decomposition with a rate constant of kcat of 0.13 s(-1) at s(s)pH 7.1.	Methanol	76-84	RUNX1 partner transcriptional co-repressor 1	Homo sapiens	179-182
17249732-3	2007	Deprotection (NaOMe, MeOH, DMF, 20 degrees C) and trapping of the transient thiolates with electrophiles have afforded the new ex-TTF trimer 19, dimeric cyclophanes 22 and 25, the tetrakis(hydroxyethylthio) derivative 23, and the strained cyclophane 24.	Methanol	21-25	ras homolog family member H	Homo sapiens	130-133
16859964-2	2007	The fluorescence intensity of the Tb-N-(2-pyridinyl) ketoacetamide (PKAA) system was greatly enhanced by the addition of triethylamine (Et(3)N) and zinc nitrate in the methanol solution.	Methanol	168-176	TATA-box binding protein associated factor 8	Homo sapiens	34-38
17081715-4	2007	During 24-72 h of incubation with a low (2x10(4) HSF cells/mL) density of cells, significant cytotoxicity was observed for methanol and ethyl acetate extracts at concentrations greater than 125 microg/mL.	Methanol	123-131	interleukin 6	Homo sapiens	49-52
17386575-2	2007	The MDM-water mixture is a new multicomponent cosolvent mixture (consisting of equal volumes of methanol, dioxane and acetonitrile, as organic solvents) that dissolves a wide range of poorly water-soluble compounds.	Methanol	96-104	secreted LY6/PLAUR domain containing 1	Homo sapiens	4-7
17113740-10	2007	Administration of the MeOH extract and the BuOH fraction of Impatiens pritzellii decreased the spleen and thymus indexes, down-regulated the levels of IgG, INF-gamma, IL-18, and up-regulated the concentration of IL-10 in the serum of mice with CIA.	Methanol	22-26	interleukin 18	Mus musculus	156-172
17113740-10	2007	Administration of the MeOH extract and the BuOH fraction of Impatiens pritzellii decreased the spleen and thymus indexes, down-regulated the levels of IgG, INF-gamma, IL-18, and up-regulated the concentration of IL-10 in the serum of mice with CIA.	Methanol	22-26	interleukin 10	Mus musculus	212-217
17252111-1	2007	The reaction of PdCl2, dppm and CS2 in CH(2)Cl(2)/MeOH results in the palladium carbodiphosphorane complex [Pd(Ph(2)PCH(2)Ph(2)PCPPh(2)CH(2)PPh(2)-P,C,P)Cl]Cl.	Methanol	50-54	chorionic somatomammotropin hormone 2	Homo sapiens	32-35
17268085-2	2007	Bioassay-guided fractionation of MeOH extract of Selaginella tamariscina (Selaginellaceae) afforded a PTP1B inhibitory compound, amentoflavone.	Methanol	33-37	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	102-107
17215371-3	2007	Based on quantum mechanics/molecular mechanics (QM/MM) calculations, the free energy for MeOH reduction of o-PQQ when MeOH is hydrogen bonded to Glu-171-CO(2)(-) and the crystal water (Wat1) is hydrogen bonded to Asp-297-CO(2)(-) is DeltaG++ = 11.7 kcal/mol, which is comparable with the experimental value of 8.5 kcal/mol.	Methanol	89-93	MTOR associated protein, LST8 homolog	Homo sapiens	185-189
16580197-2	2007	To overcome or rather, exploit this situation, a two-phase membrane reactor was developed to produce FAME from canola oil and methanol.	Methanol	126-134	benign adult familial myoclonic epilepsy 1	Homo sapiens	101-105
16580197-6	2007	The novel reactor enabled the separation of reaction products (FAME/glycerol in methanol) from the original canola oil feed.	Methanol	80-88	benign adult familial myoclonic epilepsy 1	Homo sapiens	63-67
17396588-6	2007	The ln alpha - 1/T plots for racemic chiral pesticides were linear at the range of 0-40 except for that of pyriproxyfen enantiomers in methanol/water and the chiral separations were controlled by enthalpy.	Methanol	135-143	adrenoceptor alpha 1D	Homo sapiens	7-16
17209582-4	2007	It was found that the methanol fuel cell activities of PtRu/CNF catalysts were in the order of platelet &gt; tubular &gt; herringbone.	Methanol	22-30	NPHS1 adhesion molecule, nephrin	Homo sapiens	60-63
17215371-7	2007	Starting with Wat1 removed and MeOH hydrogen bonded to Asp-297-CO(2)(-), we find that MeOH returns to be hydrogen bonded to Glu-171-CO(2)(-) and Asp-297-CO(2)(-) coordinates to Ca(2+) during 3 ns simulation.	Methanol	86-90	MTOR associated protein, LST8 homolog	Homo sapiens	14-18
17215371-3	2007	Based on quantum mechanics/molecular mechanics (QM/MM) calculations, the free energy for MeOH reduction of o-PQQ when MeOH is hydrogen bonded to Glu-171-CO(2)(-) and the crystal water (Wat1) is hydrogen bonded to Asp-297-CO(2)(-) is DeltaG++ = 11.7 kcal/mol, which is comparable with the experimental value of 8.5 kcal/mol.	Methanol	118-122	MTOR associated protein, LST8 homolog	Homo sapiens	185-189
17661322-3	2007	[VO3]- dehydrated methanol to eliminate water and form [VO2(eta2-OCH2)]-, which features an [eta2-C,O-OCH2]2- ligand formed by formal removal of two protons from methanol and which is isoelectronic with peroxide.	Methanol	18-26	DNA polymerase iota	Homo sapiens	60-64
16497434-1	2007	Methanol extract from cultured Scutellaria baicalensis cells inhibited the proliferation of human monocytic leukemia cell line THP-1 and human osteogenic sarcoma cell line HOS.	Methanol	0-8	GLI family zinc finger 2	Homo sapiens	127-132
17192073-1	2007	[reaction: see text] The new macrocycle 9 (&gt;70% yield from hydroxythiol 10) was treated with several nucleophilic reagents (RMgX, RLi, and LiAlH4) affording carbinols 12a-j (80-96% yield, &gt;99:1 dr).	Methanol	160-169	ATP binding cassette subfamily E member 1	Homo sapiens	133-136
17091496-4	2007	An analog of peptide 1 with an Aib-Gly turn-nucleated hairpin (Boc-W-L-W-U-G-W-L-W-OMe (peptide 2)) shows a preference for helical structures in solution, in both chloroform and methanol.	Methanol	178-186	ANIB1	Homo sapiens	31-34
17661322-3	2007	[VO3]- dehydrated methanol to eliminate water and form [VO2(eta2-OCH2)]-, which features an [eta2-C,O-OCH2]2- ligand formed by formal removal of two protons from methanol and which is isoelectronic with peroxide.	Methanol	18-26	DNA polymerase iota	Homo sapiens	93-97
17661322-3	2007	[VO3]- dehydrated methanol to eliminate water and form [VO2(eta2-OCH2)]-, which features an [eta2-C,O-OCH2]2- ligand formed by formal removal of two protons from methanol and which is isoelectronic with peroxide.	Methanol	162-170	DNA polymerase iota	Homo sapiens	60-64
17661322-3	2007	[VO3]- dehydrated methanol to eliminate water and form [VO2(eta2-OCH2)]-, which features an [eta2-C,O-OCH2]2- ligand formed by formal removal of two protons from methanol and which is isoelectronic with peroxide.	Methanol	162-170	DNA polymerase iota	Homo sapiens	93-97
17079731-8	2007	The uniqueness of Atg26 and Vac8 functions under different pexophagy conditions demonstrates that not only pexophagy inducers, such as glucose or ethanol, but also the inducers of peroxisomes, such as methanol, oleate, or primary amines, determine the requirements for subsequent pexophagy in yeast.	Methanol	201-209	sterol 3-beta-glucosyltransferase	Saccharomyces cerevisiae S288C	18-23
17367097-7	2007	Thus, by using dibenzoylacetylene as the C(4) electrophile, a [14+4] strategy allowed the synthesis of two hexaphenyl representatives with two or four free carbinol vertices.	Methanol	156-164	complement C4A (Rodgers blood group)	Homo sapiens	41-45
17367097-9	2007	By using the hexacarbonyldicobalt complex of butynedial as the C(4) electrophile, a [14+4] strategy also allowed the isolation of a tetraphenylhexaoxy[6]pericyclyne with two adjacent unsubstituted carbinol vertices.	Methanol	197-205	complement C4A (Rodgers blood group)	Homo sapiens	63-67
16980512-7	2007	A soluble proinflammatory substance was separated from the bacterial recombinant HMGB1 by chloroform-methanol treatment.	Methanol	101-109	high mobility group box 1	Homo sapiens	81-86
17954255-4	2007	The lipid phosphate phosphatase activities of DPP1-encoded and LPP1-encoded enzymes are measured by following the release of water-soluble radioactive inorganic phosphate from chloroform-soluble radioactive lipid phosphate substrate following a chloroform/methanol/water phase partition.	Methanol	256-264	bifunctional diacylglycerol diphosphate phosphatase/phosphatidate phosphatase	Saccharomyces cerevisiae S288C	46-50
17954255-4	2007	The lipid phosphate phosphatase activities of DPP1-encoded and LPP1-encoded enzymes are measured by following the release of water-soluble radioactive inorganic phosphate from chloroform-soluble radioactive lipid phosphate substrate following a chloroform/methanol/water phase partition.	Methanol	256-264	phosphatidate phosphatase LPP1	Saccharomyces cerevisiae S288C	63-67
17149777-0	2007	The preferred reaction path for the oxidation of methanol by PQQ-containing methanol dehydrogenase: addition-elimination versus hydride-transfer mechanism.	Methanol	49-57	malate dehydrogenase 2	Homo sapiens	76-98
17149777-1	2007	The catalytic oxidation of methanol to formaldehyde by pyrroloquinoline quinone (PQQ)-containing methanol dehydrogenase (MDH) was investigated at density functional B3LYP level.	Methanol	27-35	malate dehydrogenase 2	Homo sapiens	97-119
17149777-1	2007	The catalytic oxidation of methanol to formaldehyde by pyrroloquinoline quinone (PQQ)-containing methanol dehydrogenase (MDH) was investigated at density functional B3LYP level.	Methanol	27-35	malate dehydrogenase 2	Homo sapiens	121-124
17079731-1	2007	Sterol glucosyltransferase, Ugt51/Atg26, is essential for both micropexophagy and macropexophagy of methanol-induced peroxisomes in Pichia pastoris.	Methanol	100-108	sterol 3-beta-glucosyltransferase	Saccharomyces cerevisiae S288C	34-39
17079731-8	2007	The uniqueness of Atg26 and Vac8 functions under different pexophagy conditions demonstrates that not only pexophagy inducers, such as glucose or ethanol, but also the inducers of peroxisomes, such as methanol, oleate, or primary amines, determine the requirements for subsequent pexophagy in yeast.	Methanol	201-209	protein anchor VAC8	Saccharomyces cerevisiae S288C	28-32
17947986-2	2007	This "Mosher ester analysis" relies on the fact that the protons in diastereomeric alpha-methoxy-alpha-trifluoromethylphenylacetic acid (MTPA) esters (i.e., those derived from conjugation of the carbinol under interrogation with MTPA) display different arrays of chemical shifts (deltas) in their 1H NMR spectra.	Methanol	195-203	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha	Homo sapiens	137-141
16843053-3	2007	The number of DMF and MeOH molecules in the first solvation sphere of Co(II) ion versus solvent composition has been determined.	Methanol	22-26	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	70-76
17640167-2	2007	We also demonstrated that a methanol extract (ME) fraction from black raspberries (Rubus occidentalis) (RO; RO-ME) inhibits benzo[a]pyrene-7,8-diol-9,10-epoxide [B(a)PDE]-induced activation of NF kappa B and AP-1 in cultured mouse epidermal cells.	Methanol	28-36	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	193-203
17640167-2	2007	We also demonstrated that a methanol extract (ME) fraction from black raspberries (Rubus occidentalis) (RO; RO-ME) inhibits benzo[a]pyrene-7,8-diol-9,10-epoxide [B(a)PDE]-induced activation of NF kappa B and AP-1 in cultured mouse epidermal cells.	Methanol	28-36	jun proto-oncogene	Mus musculus	208-212
17007887-2	2006	Ganoderic acid T (GA-T), which is a lanostane triterpenoid purified from methanol extract of G. lucidum mycelia, was found to exert cytotoxicity on various human carcinoma cell lines in a dose-dependent manner, while it was less toxic to normal human cell lines.	Methanol	73-81	glycine-N-acyltransferase	Homo sapiens	18-22
17546970-5	2007	Denitrification efficiency varied from 55%/o, obtained without any addition of carbon source, to 95% when methanol was added in order to obtain a methanol/nitrate ratio of about 3 kg methanol/kg NO3- -N.	Methanol	106-114	NBL1, DAN family BMP antagonist	Homo sapiens	195-198
17181257-0	2006	Electrooxidation of methanol on upd-Ru and upd-Sn modified Pt electrodes.	Methanol	20-28	uroporphyrinogen decarboxylase	Homo sapiens	32-35
17177511-3	2006	The 100% methanol, 75% ethanol, and 40% 2-propanol extracts of black cohosh effectively displaced the specific binding of [3H]DAMGO to hMOR.	Methanol	9-17	opioid receptor mu 1	Homo sapiens	135-139
17181257-0	2006	Electrooxidation of methanol on upd-Ru and upd-Sn modified Pt electrodes.	Methanol	20-28	uroporphyrinogen decarboxylase	Homo sapiens	43-46
17181257-1	2006	The electrochemical oxidation of methanol has been investigated on underpotentially deposited-ruthenium-modified platinum electrode (upd-Ru/Pt) and on underpotentially deposited-tin-modified platinum electrode (upd-Sn/Pt).	Methanol	33-41	uroporphyrinogen decarboxylase	Homo sapiens	133-136
17181257-2	2006	The submonolayers of upd-Ru and upd-Sn on a Pt electrode increased the rate of methanol electrooxidation several times as large as that on a pure Pt electrode.	Methanol	79-87	uroporphyrinogen decarboxylase	Homo sapiens	21-24
17181257-2	2006	The submonolayers of upd-Ru and upd-Sn on a Pt electrode increased the rate of methanol electrooxidation several times as large as that on a pure Pt electrode.	Methanol	79-87	uroporphyrinogen decarboxylase	Homo sapiens	32-35
17181257-3	2006	The best performance for methanol electrooxidation was obtained on a ternary platinum based catalyst modified by upd-Ru and upd-Sn simultaneously.	Methanol	25-33	uroporphyrinogen decarboxylase	Homo sapiens	113-116
17181257-3	2006	The best performance for methanol electrooxidation was obtained on a ternary platinum based catalyst modified by upd-Ru and upd-Sn simultaneously.	Methanol	25-33	uroporphyrinogen decarboxylase	Homo sapiens	124-127
17181257-4	2006	The influence of the submonolayers of upd-Ru adatoms and upd-Sn adatoms on the oxidation of methanol in acid has been investigated.	Methanol	92-100	uroporphyrinogen decarboxylase	Homo sapiens	38-41
17181257-4	2006	The influence of the submonolayers of upd-Ru adatoms and upd-Sn adatoms on the oxidation of methanol in acid has been investigated.	Methanol	92-100	uroporphyrinogen decarboxylase	Homo sapiens	57-60
17181257-6	2006	It has been shown that as long as the amount of upd-Ru deposits were controlled in a proper range, upd-Ru deposits would enhance the methanol oxidation obtained on a Pt electrode at whichever deposition potential the upd-Ru deposits were obtained.	Methanol	133-141	uroporphyrinogen decarboxylase	Homo sapiens	48-51
17181257-6	2006	It has been shown that as long as the amount of upd-Ru deposits were controlled in a proper range, upd-Ru deposits would enhance the methanol oxidation obtained on a Pt electrode at whichever deposition potential the upd-Ru deposits were obtained.	Methanol	133-141	uroporphyrinogen decarboxylase	Homo sapiens	99-102
17181257-6	2006	It has been shown that as long as the amount of upd-Ru deposits were controlled in a proper range, upd-Ru deposits would enhance the methanol oxidation obtained on a Pt electrode at whichever deposition potential the upd-Ru deposits were obtained.	Methanol	133-141	uroporphyrinogen decarboxylase	Homo sapiens	99-102
17181257-8	2006	The enhancement effect of upd-Sn adatoms for the oxidation of methanol will disappear as the electrode potential is beyond a certain value.	Methanol	62-70	uroporphyrinogen decarboxylase	Homo sapiens	26-29
16967513-3	2006	To investigate the influence of varying these factors, we analyze the helix stability of an all-beta3-icosapeptide bearing all 20 proteinogenic amino acid side chains, which is experimentally observed to fold into a 3(14)-helix in methanol but not in water.	Methanol	231-239	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	96-101
17147363-3	2006	In the presence of [Rh(OH)(COD)]2 catalyst and triethylamine base in methanol solvent, a range of 1,5-enynes undergo an intermolecular addition with a wide variety of aryl- and alkenylboronic acids and concomitant endo-selective cyclization to yield 1-aryl and alkenyl-substituted cyclopentene derivatives as the products.	Methanol	69-77	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	27-30
17109444-3	2006	METHODS: A synthetic RNASET2 gene that was optimized for expression in the yeast Pichia pastoris was designed according to the cDNA sequence and was cloned under the control of the methanol-induced promoter fused to the alpha-mating secretion peptide.	Methanol	181-189	ribonuclease T2	Homo sapiens	21-28
17129017-2	2006	In the first (PtPb-B), Pt and Pb salts were reduced by sodium borohydride in methanol at room temperature.	Methanol	77-85	protein tyrosine phosphatase receptor type B	Homo sapiens	14-18
17129017-4	2006	The electrocatalytic activity of PtPb nanoparticles produced by both methods toward formic acid and methanol oxidation was investigated and compared to Pt and PtRu.	Methanol	100-108	protein tyrosine phosphatase receptor type B	Homo sapiens	33-37
17129017-7	2006	For methanol oxidation, the PtPb nanoparticles had onset potentials slightly positive of PtRu but exhibited higher current densities at potentials about 100 mV positive of onset.	Methanol	4-12	protein tyrosine phosphatase receptor type B	Homo sapiens	28-32
17020387-3	2006	For these anions in five solvents, H2O, D2O, CH3OH, CH3CN, and (CH3)2SO, relaxation rates followed the trend of OCN- &gt; SCN- &gt; SeCN-.	Methanol	45-50	bone gamma-carboxyglutamate protein	Homo sapiens	112-115
17134154-6	2006	For a solvent of 50:50 methanol/water (v/v), lowering the flow from 200 to 50 microL min-1 results in a 10x increase in charge exchange ionization efficiency--further flow reductions provide even greater enhancements.	Methanol	23-31	CD59 molecule (CD59 blood group)	Homo sapiens	85-90
17151464-3	2006	A 50% methanol-eluted fraction separated from HWE by XAD-4 column chromatography (MFH) had a strong inhibitory effect as compared with HWE.	Methanol	6-14	forkhead box P1	Homo sapiens	82-85
17139105-3	2006	The MeOH extract of the fruits of Bupleurum rotundifolium showed inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth.	Methanol	4-8	potassium voltage-gated channel subfamily A member 1	Homo sapiens	123-127
17085293-2	2006	The methylene chloride soluble fraction of methanol extract from the stems of S. japonica showed significant MMP-1 inhibition in primary old aged human skin fibroblasts caused by ultraviolet (UV) irradiation.	Methanol	43-51	matrix metallopeptidase 1	Homo sapiens	109-114
17032007-6	2006	After 36 h of methanol induction, ECSOD was exported into the culture medium at a concentration of approximately 440 mg/L with an antioxidative activity of 760 +/- 20 U/mg ECSOD.	Methanol	14-22	superoxide dismutase 3	Homo sapiens	34-39
17032007-6	2006	After 36 h of methanol induction, ECSOD was exported into the culture medium at a concentration of approximately 440 mg/L with an antioxidative activity of 760 +/- 20 U/mg ECSOD.	Methanol	14-22	superoxide dismutase 3	Homo sapiens	172-177
17154514-3	2006	The higher cytotoxicities of [Rh2(micro-O2CCH3)2(eta1-O2CCH3)L(MeOH)]+ (L=dppz, 7; L=dppn, 8) relative to [Rh2(micro-O2CCH3)2(bpy)L]2+ (L=dppz, 10; L=dppn, 11) are attributed to the labile equatorial groups in 7 and 8 not present in 10 and 11.	Methanol	63-68	secreted phosphoprotein 1	Homo sapiens	49-53
17047739-2	2006	Accordingly, the interaction of cobalt(II) acetate with H(3)L in methanol gives rise to the discrete complex [Co(III)(2)L(OAc)(2)(OMe)]*1.5H(2)O.MeOH, 1.	Methanol	65-73	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	110-117
17047739-2	2006	Accordingly, the interaction of cobalt(II) acetate with H(3)L in methanol gives rise to the discrete complex [Co(III)(2)L(OAc)(2)(OMe)]*1.5H(2)O.MeOH, 1.	Methanol	145-149	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	110-117
17047739-5	2006	Decreasing the pH of the medium, by addition of a second mol of dicarboxylic acid, leads to [Co(II/III)(2)L(O(2)CCH(2)CO(2))(MeOH)]*2MeOH, 4, while the reaction with terephthalic acid does not proceed.	Methanol	125-130	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	99-102
16927356-0	2006	2D NMR spectroscopic evidence for unprecedented interactions of cis-[Rh2(dap)(mu-O2CCH3)2(eta1-O2CCH3)(CH3OH)](O2CCH3) with a DNA oligonucleotide: combination of intercalative and coordinative binding.	Methanol	103-110	secreted phosphoprotein 1	Homo sapiens	90-94
16397771-3	2006	In shake-flask culture induced with methanol, the recombinant human AChE (rhAChE) content was about 76% of the total secreted proteins, and rhAChE activity in supernatant was 40 U/ml.	Methanol	36-44	acetylcholinesterase (Cartwright blood group)	Homo sapiens	68-72
16933910-2	2006	The methanol solvated species has been studied by X-ray diffraction, and single crystals form in the space group P2(1)/n.	Methanol	4-12	cyclin dependent kinase inhibitor 1A	Homo sapiens	113-118
21783700-8	2006	The results show the typical ladder profile of oligonucleosomal fragments characteristics of apoptosis and the secreted cytosolic cytochrome c level was increased by treatment of methanol fraction of UD.	Methanol	179-187	cytochrome c, somatic	Homo sapiens	130-142
16894482-4	2006	In high-density fermentation in a 300 liter fermentor using a simple culture medium composed mainly of salt and methanol, the C-peptide precursor was overexpressed to a level of 2.28 g per liter.	Methanol	112-120	insulin	Homo sapiens	126-135
16910672-6	2006	The mechanism for addition of water and methanol (ROH; R = H, Me) to 4, 5, and the model compound 1,1-bis(silyl)-2,2-dimethylsilene (3a) has been studied computationally at the B3LYP/6-31G(d) and MP2/6-31G(d) levels of theory.	Methanol	40-48	major intrinsic protein of lens fiber	Homo sapiens	196-201
21158097-4	2006	The products induced by methanol were precipitated by ammonium sulfate, then CM-cellulose chromatography was performed for SM22alpha.	Methanol	24-32	transgelin	Homo sapiens	123-132
21158097-6	2006	RESULTS: The positive clone with SM22alpha got high output at 84 hours after induction by methanol.	Methanol	90-98	transgelin	Homo sapiens	33-42
17025126-6	2006	The electrocatalytic activity of the platinum catalyst supported on TiO2 nanotubes for methanol oxidation is found to be better than that of the standard commercial E-TEK catalyst.	Methanol	87-95	TEK receptor tyrosine kinase	Homo sapiens	167-170
17723553-6	2006	This compound is subsequently retained onto a C18 disk followed by spectrophotometric detection at 540 nm, and it is then eluted with methanol in water (80%, v/v), so that the C18 disk is regenerated for subsequent experiments.	Methanol	134-142	Bardet-Biedl syndrome 9	Homo sapiens	176-179
17441044-2	2006	[Ru(OSO2CF3){(S,S)-TsNCH(C6H5)CH(C6H5)NH2}(eta(6)-p-cymene)] catalyzes the asymmetric hydrogenation of acetophenone in methanol to afford (S)-1-phenylethanol with 96% ee in 100% yield.	Methanol	119-127	endothelin receptor type A	Homo sapiens	43-46
16877768-3	2006	At 30% (v/v) methanol, rmethuG-CSF has ANS binding ability.	Methanol	13-21	colony stimulating factor 2	Homo sapiens	31-34
16644126-4	2006	U. conglobata methanol extracts significantly attenuated the neurotoxicity induced by glutamate in HT22 cells and inhibited nitric oxide production induced by IFN-gamma in BV2 cells.	Methanol	14-22	interferon gamma	Mus musculus	159-168
16644126-5	2006	U. conglobata methanol extract treatments were also examined and it was found that they almost completely suppressed the expression of the proinflammatory enzyme cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS).	Methanol	14-22	prostaglandin-endoperoxide synthase 2	Mus musculus	162-178
16644126-5	2006	U. conglobata methanol extract treatments were also examined and it was found that they almost completely suppressed the expression of the proinflammatory enzyme cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS).	Methanol	14-22	prostaglandin-endoperoxide synthase 2	Mus musculus	180-185
16644126-5	2006	U. conglobata methanol extract treatments were also examined and it was found that they almost completely suppressed the expression of the proinflammatory enzyme cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS).	Methanol	14-22	nitric oxide synthase 2, inducible	Mus musculus	191-222
16616465-6	2006	L-carnitine, combined with the lower dose of methanol, stimulated NADPH-cytochrome P450 reductase after 48 h and cytochrome b5 and NADH-cytochrome b5 reductase over the whole period of observation.	Methanol	45-53	cytochrome b5 type A	Rattus norvegicus	66-126
16616465-8	2006	Methanol stimulated CYP2E1 at 24 h, but CYP1A2 at 96 h in the studied doses.	Methanol	0-8	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	20-26
16616465-9	2006	CYP2B1/2 was induced by the lower dose of methanol at 24 h but by the higher one at 96 h. When given together, L-carnitine and methanol (1/2 LD50) significantly stimulated CYP2E1 up to 170% at 24 h and 145% at 96 h.	Methanol	42-50	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	0-6
16616465-9	2006	CYP2B1/2 was induced by the lower dose of methanol at 24 h but by the higher one at 96 h. When given together, L-carnitine and methanol (1/2 LD50) significantly stimulated CYP2E1 up to 170% at 24 h and 145% at 96 h.	Methanol	42-50	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	172-178
16616465-9	2006	CYP2B1/2 was induced by the lower dose of methanol at 24 h but by the higher one at 96 h. When given together, L-carnitine and methanol (1/2 LD50) significantly stimulated CYP2E1 up to 170% at 24 h and 145% at 96 h.	Methanol	127-135	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	0-6
16616465-9	2006	CYP2B1/2 was induced by the lower dose of methanol at 24 h but by the higher one at 96 h. When given together, L-carnitine and methanol (1/2 LD50) significantly stimulated CYP2E1 up to 170% at 24 h and 145% at 96 h.	Methanol	127-135	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	172-178
16877768-0	2006	Methanol-induced tertiary and secondary structure changes of granulocyte-colony stimulating factor.	Methanol	0-8	colony stimulating factor 3	Homo sapiens	61-98
16877768-1	2006	We have studied methanol-induced conformational changes in rmethuG-CSF at pH 2.5 by means of circular dichroism (CD), fluorescence and infrared (IR) spectroscopy, and 8-anilino-1-naphthalene sulfonic acid (ANS) binding.	Methanol	16-24	colony stimulating factor 2	Homo sapiens	67-70
16806813-0	2006	Methanol alters ecto-nucleotidases and acetylcholinesterase in zebrafish brain.	Methanol	0-8	acetylcholinesterase	Danio rerio	39-59
16806813-3	2006	Here we tested the acute effect of methanol on ecto-nucleotidase (NTPDase, ecto-5"-nucleotidase) and acetylcholinesterase (AChE) activities in zebrafish brain.	Methanol	35-43	acetylcholinesterase	Danio rerio	101-121
16806813-6	2006	A significant inhibition on AChE activity (39%, 33% and 30%) was observed at the range of 0.25% to 1.0% methanol exposure.	Methanol	104-112	acetylcholinesterase	Danio rerio	28-32
16806813-8	2006	Methanol was able to inhibit NTPDase1, two isoforms of NTPDase2 and AChE transcripts.	Methanol	0-8	ectonucleoside triphosphate diphosphohydrolase 1	Danio rerio	29-37
16806813-8	2006	Methanol was able to inhibit NTPDase1, two isoforms of NTPDase2 and AChE transcripts.	Methanol	0-8	acetylcholinesterase	Danio rerio	68-72
16574131-2	2006	Hexafluorophosphate (PF(6)(-)) adsorption isotherms were measured from acetonitrile/water and methanol/water mixtures.	Methanol	94-102	sperm associated antigen 17	Homo sapiens	21-26
16439081-0	2006	Activation of the mu-opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS.	Methanol	59-67	opioid receptor mu 1	Homo sapiens	18-36
16497458-2	2006	The present study aims to investigate the effect of the methanol extract of Smilacis chinae rhizome (SCR) from Smilax china L. (Liliaceae) on amyloid beta protein (Abeta) (25-35), a synthetic 25-35 amyloid peptide, -induced neurotoxicity in cultured rat cerebral cortical neurons.	Methanol	56-64	amyloid beta precursor protein	Rattus norvegicus	164-169
16574131-5	2006	Methanol, on the other hand, causes a steady decrease of PF(6)(-) adsorption with increased organic concentration in the mobile phase.	Methanol	0-8	sperm associated antigen 17	Homo sapiens	57-62
16784225-7	2006	For cpn10, both MeOH and TFE additions govern initial unfolding; however, further additions of MeOH result in the formation of a non-native beta-structure, whereas subsequent additions of TFE induce a superhelical structure.	Methanol	16-20	heat shock protein family E (Hsp10) member 1	Homo sapiens	4-9
16636060-4	2006	AglB is an unusual NAD+/Mn2+-dependent phospho-alpha-glucosidase that promotes growth of MG-1655 (pAP1) by catalyzing the in vivo hydrolysis of methyl-alpha-D-glucopyranoside 6-phosphate to yield glucose 6-phosphate and methanol.	Methanol	220-228	glycoside hydrolase	Escherichia coli str. K-12 substr. MG1655	47-64
16784225-7	2006	For cpn10, both MeOH and TFE additions govern initial unfolding; however, further additions of MeOH result in the formation of a non-native beta-structure, whereas subsequent additions of TFE induce a superhelical structure.	Methanol	95-99	heat shock protein family E (Hsp10) member 1	Homo sapiens	4-9
16749821-2	2006	A tetranuclear cubane, [Co4(1-H)4Cl4(H2O)3(CH3OH)], was isolated from the reaction of 1 with CoCl2.6H2O and NaOH in MeOH, and a tetranuclear double cubane, [Co4(1-H)6(NO3)2], was isolated from the reaction of 1 with Co(NO3)2.6H2O and NEt3 in MeOH.	Methanol	43-48	tetraspanin 2	Homo sapiens	234-238
16677702-1	2006	Effect of six organic solvents-methanol, ethanol, propanol, dimethyl sulphoxide (DMSO), N,N-dimethyl formamide (DMF), and glycerol on the conformation and interaction of catalase and anticatalase antibodies were studied with the aim of identifying the solvents in which antigen-antibody interactions are strong.	Methanol	31-39	catalase	Homo sapiens	170-178
16722709-2	2006	On the microsecond time scale, [HO2] exhibited a time dependence consistent with a mechanism in which [HO2] approached equilibrium via HO2 + HO2.CH3OH (3, -3).	Methanol	145-150	heme oxygenase 2	Homo sapiens	103-106
16722709-2	2006	On the microsecond time scale, [HO2] exhibited a time dependence consistent with a mechanism in which [HO2] approached equilibrium via HO2 + HO2.CH3OH (3, -3).	Methanol	145-150	heme oxygenase 2	Homo sapiens	103-106
16722709-4	2006	The effective bimolecular rate constant, k3, for formation of the HO2.CH3OH complex is .10(-15).exp[(1800 +/- 500)/T] cm3 molecule(-1) s(-1) at 100 Torr (1 sigma).	Methanol	70-75	heme oxygenase 2	Homo sapiens	66-69
16722709-5	2006	Ab initio calculations of the optimized structure and energetics of the HO2.CH3OH complex were performed at the CCSD(T)/6-311++G(3df,3pd)//MP2(full)/6-311++G(2df,2pd) level.	Methanol	76-81	heme oxygenase 2	Homo sapiens	72-75
16722709-6	2006	The complex was found to have a strong hydrogen bond (D(e) = 43.9 kJ mol(-1)) with the hydrogen in HO2 binding to the oxygen in CH3OH.	Methanol	128-133	heme oxygenase 2	Homo sapiens	99-102
16722709-0	2006	Experimental and ab initio study of the HO2.CH3OH complex: thermodynamics and kinetics of formation.	Methanol	44-49	heme oxygenase 2	Homo sapiens	40-43
16722709-1	2006	Near-infrared spectroscopy was used to monitor HO2 formed by pulsed laser photolysis of Cl2-O2-CH3OH-N2 mixtures.	Methanol	95-100	heme oxygenase 2	Homo sapiens	47-50
16722709-2	2006	On the microsecond time scale, [HO2] exhibited a time dependence consistent with a mechanism in which [HO2] approached equilibrium via HO2 + HO2.CH3OH (3, -3).	Methanol	145-150	heme oxygenase 2	Homo sapiens	32-35
16722709-2	2006	On the microsecond time scale, [HO2] exhibited a time dependence consistent with a mechanism in which [HO2] approached equilibrium via HO2 + HO2.CH3OH (3, -3).	Methanol	145-150	heme oxygenase 2	Homo sapiens	103-106
16564531-1	2006	Plots of the retention factor against mobile phase composition were used to organize a varied group of solutes into three categories according to their retention mechanism on an octadecylsiloxane-bonded silica stationary phase HyPURITY C18 with methanol-water and acetonitrile-water mobile phase compositions containing 10-70% (v/v) organic solvent.	Methanol	245-253	Bardet-Biedl syndrome 9	Homo sapiens	236-239
16709066-2	2006	Ring opening of the aziridine moiety with N-chlorosuccinimide in CCl4 and subsequent treatment of the thus formed 4-chloro-3-(N-chloro-N-(alpha,alpha-dichlorobenzyl)amino)butanenitriles with sodium methoxide in methanol resulted in novel methyl N-(2-chloro-1-(cyanomethyl)ethyl)benzimidates, although in low yields.	Methanol	191-207	C-C motif chemokine ligand 4	Homo sapiens	65-69
16709066-2	2006	Ring opening of the aziridine moiety with N-chlorosuccinimide in CCl4 and subsequent treatment of the thus formed 4-chloro-3-(N-chloro-N-(alpha,alpha-dichlorobenzyl)amino)butanenitriles with sodium methoxide in methanol resulted in novel methyl N-(2-chloro-1-(cyanomethyl)ethyl)benzimidates, although in low yields.	Methanol	211-219	C-C motif chemokine ligand 4	Homo sapiens	65-69
16439134-4	2006	Spin adducts from other oxygen- and carbon-centered radicals (e.g., derived from methanol or linoleic acid hydroperoxide) are also described.	Methanol	81-89	spindlin 1	Homo sapiens	0-4
16755926-2	2006	The expression of hTumstatin in GS115(pPICZalpha-tum)was then induced by methanol and secreted into the culture medium, with a yield of 25mg/L as shown by SDS-PAGE and Western blotting.	Methanol	73-81	collagen type IV alpha 3 chain	Homo sapiens	18-28
16564515-7	2006	Administration of methanol showed significant increase in enzymatic (superoxide dismutase, catalase, glutathione peroxidase), non-enzymatic (reduced glutathione and Vitamin C) antioxidants and lipid peroxidation (LPO) in hypothalamus and adrenal gland of day 1 group.	Methanol	18-26	catalase	Rattus norvegicus	91-99
16330252-7	2006	In addition, a method of estimation of cooperativity factors Ab and AOX in system (CH3OH)2...B is proposed.	Methanol	83-88	acyl-CoA oxidase 1	Homo sapiens	68-71
16677031-8	2006	The deacetylation of 3 was achieved by treatment with sodium methoxide in dry 1,4-dioxane to produce the PSt microgel with maltohexaose as the hydrophilic segment, 4, as a white solid.	Methanol	54-70	sulfotransferase family 1A member 1	Homo sapiens	105-108
16426790-6	2006	The mobile phase was methanol-water-glacial acetic acid (10:89.96:0.04 v/v/v, pH 3.5) delivered to the column at 1 ml min-1 and the column temperature was maintained at 30 degrees C. Galactosamine hydrochloride (Gal-HCl) was used as an internal standard.	Methanol	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	118-123
16595900-10	2006	This finding indicates that the active component of hop is included in MFH, which was absorbed to Amberlite XAD-4 and eluted with 50% methanol.	Methanol	134-142	HOP homeobox	Homo sapiens	52-55
16516487-6	2006	After induction with methanol, the expression level of rhApoAI (recombinant human ApoAI) was 160 mg/L in a 14L fermentor.	Methanol	21-29	apolipoprotein A1	Homo sapiens	57-62
16529478-1	2006	Reactions of Hg(OAc)2 with 2 equiv of TabHPF6 [TabH = 4-(trimethylammonio)benzenethiol] in MeCN/MeOH afforded a mononuclear linear complex [Hg(Tab)2](PF6)2 (1).	Methanol	96-100	sperm associated antigen 17	Homo sapiens	42-45
16183240-2	2006	After extraction of lincomycin from premix with extraction solvent the extract is applied to OASIS HLB column treated with methanol and water.	Methanol	123-131	cAMP responsive element binding protein 3 like 1	Homo sapiens	93-98
16425170-2	2006	For stannylcupration of an ynone substrate, only the anti-addition product is observed, whereas for the corresponding ynoate substrate, the stereoselectivity can be affected by the reaction conditions: in the presence of methanol as proton donor, the initial syn-addition product can be trapped, whereas a syn/anti mixture is obtained in a non-protic solvent.	Methanol	221-229	synemin	Homo sapiens	259-262
16425170-2	2006	For stannylcupration of an ynone substrate, only the anti-addition product is observed, whereas for the corresponding ynoate substrate, the stereoselectivity can be affected by the reaction conditions: in the presence of methanol as proton donor, the initial syn-addition product can be trapped, whereas a syn/anti mixture is obtained in a non-protic solvent.	Methanol	221-229	synemin	Homo sapiens	306-309
16522119-6	2006	The addition of methanol and of hexafluoro-2-propanol to 1 in aprotic solvents models the PLP-water interaction in the enzymatic active site.	Methanol	16-24	proteolipid protein 1	Homo sapiens	90-93
16465400-2	2006	Fifty percent methanol extract of MEC powder showed potent inhibitory activity against histamine release from basophils of patients suffering from seasonal allergic rhinitis to ceder pollen.	Methanol	14-22	C-C motif chemokine ligand 28	Homo sapiens	34-37
16508179-2	2006	The CH2Cl2/MeOH extract of the stem bark of Oriciopsis glaberrima ENGL.	Methanol	11-15	exo/endonuclease G	Homo sapiens	66-70
16542568-2	2006	The Fourier transform infrared (FT-IR) spectra of the enzyme obtained in chloroform, methanol, and acetonitrile showed an absorption band at 1617 cm(-1) indicative of significant protein aggregation, whereas spectra of lipoxygenase in hexane and octane exhibited substantially less aggregate formation.	Methanol	85-93	linoleate 9S-lipoxygenase-4	Glycine max	219-231
16629272-3	2006	Solutions of ethanol or methanol in water also effectively desorbed RDX, although methanol was somewhat less effective than ethanol.	Methanol	24-32	radixin	Homo sapiens	68-71
16202612-0	2006	Tyrosinase inhibitory cycloartane type triterpenoids from the methanol extract of the whole plant of Amberboa ramosa Jafri and their structure-activity relationship.	Methanol	62-70	tyrosinase	Homo sapiens	0-10
16202612-1	2006	New tyrosinase inhibitory cycloartane triterpenoids have been discovered from the methanol extract of the whole plant of Amberboa ramosa (Roxb.)	Methanol	82-90	tyrosinase	Homo sapiens	4-14
16482323-1	2006	The (1,0) band of the A6sigma+-X6sigma+ electronic transition of CrH has been observed by laser-induced fluorescence following the reaction of laser-ablated Cr atoms with methanol under supersonic free-jet cooled conditions.	Methanol	171-179	corticotropin releasing hormone	Homo sapiens	65-68
16434242-7	2006	The current study describes an enantioselective method that utilises pre-column formation of fluorescent diastereomers that are resolved on a C18 HPLC column using a gradient of methanol and water.	Methanol	178-186	Bardet-Biedl syndrome 9	Homo sapiens	142-145
16534734-1	2006	During the screening for diacylglycerol acyltransferase (DGAT) inhibitors from natural products, the lupane-type triterpenoid betulinic acid was isolated from the methanol extract of Alnus hirsuta.	Methanol	163-171	diacylglycerol O-acyltransferase 1	Rattus norvegicus	57-61
16183122-8	2006	Methanol modifier (BDH, for pesticide residue analysis, 10 mL) was added to water sample for better extraction.	Methanol	0-8	3-hydroxybutyrate dehydrogenase 1	Homo sapiens	19-22
16424336-3	2006	We found that a p-H2 matrix inhibits rotation of isolated methanol (CH3OH) but still allows internal rotation about the C-O bond, with splittings of the E/A torsional doublet in internal rotation-coupled vibrational modes that are qualitatively consistent with those for CH3OH in the gaseous phase.	Methanol	58-66	polyhomeotic homolog 2	Homo sapiens	16-20
16289559-6	2006	Shorter alkyl-bonded-chains (C18 versus C30) and the end-capping of the silica surface contribute to decrease the surface heterogeneity under the same experimental conditions (30% methanol, 25 mM NaCl).	Methanol	180-188	Bardet-Biedl syndrome 9	Homo sapiens	29-32
16325848-7	2006	Acetone-methanol showed a lower percentage of positive cells for CD68 and a poor quality.	Methanol	8-16	CD68 molecule	Homo sapiens	65-69
16325848-8	2006	PLP-sucrose gives the best results for the preservation of the studied cell markers and acetone-methanol the worst.	Methanol	96-104	proteolipid protein 1	Homo sapiens	0-3
16424336-3	2006	We found that a p-H2 matrix inhibits rotation of isolated methanol (CH3OH) but still allows internal rotation about the C-O bond, with splittings of the E/A torsional doublet in internal rotation-coupled vibrational modes that are qualitatively consistent with those for CH3OH in the gaseous phase.	Methanol	68-73	polyhomeotic homolog 2	Homo sapiens	16-20
16424336-3	2006	We found that a p-H2 matrix inhibits rotation of isolated methanol (CH3OH) but still allows internal rotation about the C-O bond, with splittings of the E/A torsional doublet in internal rotation-coupled vibrational modes that are qualitatively consistent with those for CH3OH in the gaseous phase.	Methanol	271-276	polyhomeotic homolog 2	Homo sapiens	16-20
17009246-6	2006	The activities of superoxide dismutase and catalase were decreased in the brain following methanol exposure, whereas in methanol- and ethanol-coexposed animals there was no significant effect on these enzymes as compared to methanol-exposed animals.	Methanol	90-98	catalase	Homo sapiens	43-51
16182479-3	2006	The total crude extract (100 microg/ml) prepared with 80% methanol (MeOH extract) and its fractions (100 microg/ml) obtained by solvent partition with hexane and ethyl acetate (EtOAc) significantly blocked the production of interleukin (IL)-1 beta, IL-6 and the tumor necrosis factor (TNF)-alpha from RAW264.7 cells stimulated by lipopolysaccharide (LPS) up to 20-70%.	Methanol	68-72	interleukin 1 beta	Mus musculus	224-247
16182479-3	2006	The total crude extract (100 microg/ml) prepared with 80% methanol (MeOH extract) and its fractions (100 microg/ml) obtained by solvent partition with hexane and ethyl acetate (EtOAc) significantly blocked the production of interleukin (IL)-1 beta, IL-6 and the tumor necrosis factor (TNF)-alpha from RAW264.7 cells stimulated by lipopolysaccharide (LPS) up to 20-70%.	Methanol	68-72	interleukin 6	Mus musculus	249-253
16182479-3	2006	The total crude extract (100 microg/ml) prepared with 80% methanol (MeOH extract) and its fractions (100 microg/ml) obtained by solvent partition with hexane and ethyl acetate (EtOAc) significantly blocked the production of interleukin (IL)-1 beta, IL-6 and the tumor necrosis factor (TNF)-alpha from RAW264.7 cells stimulated by lipopolysaccharide (LPS) up to 20-70%.	Methanol	68-72	tumor necrosis factor	Mus musculus	262-295
17260508-3	2006	A viscous PLCL solution was spun as a gel-phase under swirl-flow conditions and was subsequently fabricated to produce a tubular fibrous scaffold on a rotating cylindrical shaft in a methanol solution.	Methanol	183-191	phospholipase C like 1 (inactive)	Homo sapiens	10-14
16390200-2	2006	This temperature activation of PME has been investigated by measuring the formation of methanol in intact tissue of green beans and tomatoes.	Methanol	87-95	pectinesterase/pectinesterase inhibitor U1	Solanum lycopersicum	31-34
17191442-7	2006	The latter method can reproduce the observed fractional abundance of gas-phase methanol and many other gas-phase species in the well-studied cold dark cloud TMC1-CP but the best fit to the observational data occurs at times significantly later than at ages estimated from gas-phase models.	Methanol	79-87	transmembrane channel like 1	Homo sapiens	157-161
17009246-7	2006	The activity of acetylcholinesterase was significantly reduced in the methanol-exposed animals.	Methanol	70-78	acetylcholinesterase (Cartwright blood group)	Homo sapiens	16-36
16129618-2	2006	The aim of this study was to evaluate acetylcholinesterase (AChE) activity in human erythrocyte membranes after incubation with the sum of ASP metabolites, phenylalanine (Phe), methanol (met) and aspartic acid (aspt), or with each one separately.	Methanol	177-185	acetylcholinesterase (Cartwright blood group)	Homo sapiens	38-58
17135161-2	2006	Tyrosinase-inhibiting material was extracted with solvents methanol, acetone, ethanol, dimethyl sulphoxide in water, and with water only.	Methanol	59-67	tyrosinase	Homo sapiens	0-10
17135161-3	2006	Methanol has been found to be suitable for extracting adequate amounts of tyrosinase-inhibiting component from the natural thallus.	Methanol	0-8	tyrosinase	Homo sapiens	74-84
16484759-5	2006	Administration of methanol at 15 and 30 d significantly (p&lt;0.05) increased lipid peroxidation and decreased the enzymatic (superoxide dismutase, catalase, glutathione peroxidase) and non-enzymatic antioxidants (reduced glutathione and vitamin C) in lymphoid organs.	Methanol	18-26	catalase	Rattus norvegicus	148-156
16129618-2	2006	The aim of this study was to evaluate acetylcholinesterase (AChE) activity in human erythrocyte membranes after incubation with the sum of ASP metabolites, phenylalanine (Phe), methanol (met) and aspartic acid (aspt), or with each one separately.	Methanol	177-185	acetylcholinesterase (Cartwright blood group)	Homo sapiens	60-64
16285776-0	2005	The application of diffuse reflectance infrared spectroscopy and temperature-programmed desorption to investigate the interaction of methanol on eta-alumina.	Methanol	133-141	endothelin receptor type A	Homo sapiens	145-148
16360935-2	2006	The MeOH-soluble fractions of 25 samples, prepared from water extracts, demonstrated inhibitory activity more than 50% on the metabolism mediated by CYP3A4, and 21 samples on the metabolism mediated by CYP2D6.	Methanol	4-8	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	149-155
17044120-5	2006	Gemini C18 column using a gradient system with 10 mM ammonium hydroxide and methanol.	Methanol	76-84	Bardet-Biedl syndrome 9	Homo sapiens	7-10
16618987-5	2006	However, at a low concentration of H2O2 and in the presence of a suitable hydrogen donor, e.g. ethanol, methanol, phenol, and others, catalase acts peroxidically, removing H2O2, but oxidizing its substrate (peroxidatic reaction).	Methanol	104-112	catalase	Homo sapiens	134-142
15970461-2	2006	In protic methanol, 1 crystallizes in monoclinic space group P2(1)/c (1a) comprising of 2D hydrogen bonded network via cyclic dimers.	Methanol	10-18	cyclin dependent kinase inhibitor 1A	Homo sapiens	61-68
16722316-3	2006	PI3-K activity was assayed by incubation recombinant PI3-K p110beta with phosphatidylinostiol-4,5-bisphosphate and [gamma-32P] ATP; the 32P-radiolabeled lipids were extracted with cholroform and methanol, and assessed by scintillation counter.	Methanol	195-203	peptidase inhibitor 3	Homo sapiens	0-3
16722316-3	2006	PI3-K activity was assayed by incubation recombinant PI3-K p110beta with phosphatidylinostiol-4,5-bisphosphate and [gamma-32P] ATP; the 32P-radiolabeled lipids were extracted with cholroform and methanol, and assessed by scintillation counter.	Methanol	195-203	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	59-67
16366642-0	2005	B3LYP and MP2 calculations of the enthalpies of hydrogen-bonded complexes of methanol with neutral bases and anions: comparison with experimental data.	Methanol	77-85	tryptase pseudogene 1	Homo sapiens	10-13
16375389-10	2005	Because of the analogy between methanol dissociation and the removal of the first chlorine atom in the destructive adsorption of CCl4, the sites enabling twofold coordination were likely to be the same Lewis acid sites actively involved in the destructive adsorption of CCl4.	Methanol	31-39	C-C motif chemokine ligand 4	Homo sapiens	129-133
16375389-10	2005	Because of the analogy between methanol dissociation and the removal of the first chlorine atom in the destructive adsorption of CCl4, the sites enabling twofold coordination were likely to be the same Lewis acid sites actively involved in the destructive adsorption of CCl4.	Methanol	31-39	C-C motif chemokine ligand 4	Homo sapiens	270-274
16327161-3	2005	A MeOH extract of Symphyocladia latiuscula (Rhodomelaceae) and its fractions exhibited antiviral activities against acyclovir (ACV) and phosphonoacetic acid (PAA)-resistant (AP(r)) herpes simplex type 1 (HSV-1), thymidine kinase (TK(-)) deficient HSV-1 and wild type HSV-1 in vitro without cytotoxicity.	Methanol	2-6	involved in nucleotide metabolism	Human alphaherpesvirus 1	212-235
16125889-2	2005	Water extracts, a 70% methanol (MeOH) extract and an ethyl acetate (EtOAc) soluble fraction (III) from DJW inhibited platelet-activating factor (PAF)-induced platelet aggregation in vitro and in vivo assays.	Methanol	22-30	PCNA clamp associated factor	Homo sapiens	145-148
16125889-2	2005	Water extracts, a 70% methanol (MeOH) extract and an ethyl acetate (EtOAc) soluble fraction (III) from DJW inhibited platelet-activating factor (PAF)-induced platelet aggregation in vitro and in vivo assays.	Methanol	32-36	PCNA clamp associated factor	Homo sapiens	145-148
16351277-1	2005	Viscosity (eta) measurements using rolling sphere viscometry in a resistance-heated diamond-anvil pressure cell yield activation energies of 18-98 kJmol over a pressure range of 1.1-6.1 GPa for methanol and 26-78 kJmol over a pressure range of 2.9-5.4 GPa for a 4:1 methanol:ethanol solution.	Methanol	194-202	endothelin receptor type A	Homo sapiens	11-14
16285776-1	2005	The adsorption of methanol and its subsequent transformation to form dimethyl ether (DME) on a commercial grade eta-alumina catalyst has been investigated using a combination of mass selective temperature-programmed desorption (TPD) and diffuse reflectance infrared spectroscopy (DRIFTS).	Methanol	18-26	endothelin receptor type A	Homo sapiens	112-115
16351277-1	2005	Viscosity (eta) measurements using rolling sphere viscometry in a resistance-heated diamond-anvil pressure cell yield activation energies of 18-98 kJmol over a pressure range of 1.1-6.1 GPa for methanol and 26-78 kJmol over a pressure range of 2.9-5.4 GPa for a 4:1 methanol:ethanol solution.	Methanol	266-274	endothelin receptor type A	Homo sapiens	11-14
16285776-2	2005	The infrared spectrum of a saturated overlayer of methanol on eta-alumina shows the surface to be comprised of associatively adsorbed methanol and chemisorbed methoxy species.	Methanol	50-58	endothelin receptor type A	Homo sapiens	62-65
16285776-2	2005	The infrared spectrum of a saturated overlayer of methanol on eta-alumina shows the surface to be comprised of associatively adsorbed methanol and chemisorbed methoxy species.	Methanol	134-142	endothelin receptor type A	Homo sapiens	62-65
16285776-7	2005	The overall processes involved in (i) the adsorption/desorption of methanol, (ii) the transformation of methanol to DME, and (iii) the formation and decomposition of formate species are discussed within the context of a recently developed four-site model for the Lewis acidity of eta-alumina.	Methanol	67-75	endothelin receptor type A	Homo sapiens	280-283
16078289-9	2005	K[SiPh(AnErytH(-2))(2)]1/2 MeOH (9) is a prototypical example as it shows the two most significant isomers in one crystal structure: the syn/anti and the anti/anti form (syn and anti define the oxolane ring orientation close to, or apart from, the monodentate ligand, respectively).	Methanol	27-31	synemin	Homo sapiens	137-140
16234939-1	2005	Reaction of the tetradentate ligand N-(2-hydroxybenzyl)-N,N-bis(2-pyridylmethyl)amine (L-OH) with MoO2Cl2 in methanol in the presence of NaOMe and PF6- results in the formation of [MoO2(L-O)]PF6.	Methanol	109-117	sperm associated antigen 17	Homo sapiens	147-150
16234939-1	2005	Reaction of the tetradentate ligand N-(2-hydroxybenzyl)-N,N-bis(2-pyridylmethyl)amine (L-OH) with MoO2Cl2 in methanol in the presence of NaOMe and PF6- results in the formation of [MoO2(L-O)]PF6.	Methanol	109-117	sperm associated antigen 17	Homo sapiens	191-194
16234939-5	2005	Reaction of [MoO2(L-O)]PF6 with PPh3 in other solvents than methanol leads to the formation of the Mo(V) dimer [(L-O)OMo(micro-O)MoO(L-O)](PF6)2.	Methanol	60-68	sperm associated antigen 17	Homo sapiens	23-26
16350854-4	2005	The methanol extract from the crude drug were found to significantly inhibit VEGF binding to the VEGF receptor (IC50 approximately = 27 microg/mL).	Methanol	4-12	vascular endothelial growth factor A	Homo sapiens	77-81
16350854-4	2005	The methanol extract from the crude drug were found to significantly inhibit VEGF binding to the VEGF receptor (IC50 approximately = 27 microg/mL).	Methanol	4-12	vascular endothelial growth factor A	Homo sapiens	97-101
16222729-2	2005	The cDNAs encoding human CYP2D6 and human NADPH-P450 oxidoreductase (CPR) were transformed into the methylotrophic yeast Pichia pastoris and expressed with control of the methanol-inducible AOX1 promoter.	Methanol	171-179	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	25-31
16222729-2	2005	The cDNAs encoding human CYP2D6 and human NADPH-P450 oxidoreductase (CPR) were transformed into the methylotrophic yeast Pichia pastoris and expressed with control of the methanol-inducible AOX1 promoter.	Methanol	171-179	cytochrome p450 oxidoreductase	Homo sapiens	69-72
16853611-7	2005	The specific activity of Pt catalyst supported on the carbon materials for room-temperature methanol electrochemical oxidation was observed to be higher than that of a commercial Pt catalyst (E-TEK).	Methanol	92-100	TEK receptor tyrosine kinase	Homo sapiens	194-197
16269173-3	2005	In mice, catalase is involved in ethanol and methanol metabolism, but not in the metabolism of other alcohols such as 1-propanol or tert-butanol.	Methanol	45-53	catalase	Mus musculus	9-17
16270228-9	2005	However, comparative metabolic profiling of the methanol-soluble phenolic fraction from basal xylem revealed significant differences between CAD1 down-regulated and wild-type plants.	Methanol	48-56	probable cinnamyl alcohol dehydrogenase 1	Nicotiana tabacum	141-145
16078289-9	2005	K[SiPh(AnErytH(-2))(2)]1/2 MeOH (9) is a prototypical example as it shows the two most significant isomers in one crystal structure: the syn/anti and the anti/anti form (syn and anti define the oxolane ring orientation close to, or apart from, the monodentate ligand, respectively).	Methanol	27-31	synemin	Homo sapiens	170-173
16149778-3	2005	A stereoselective reduction of the Cbz-protected aminoketone obtained from this radical reaction was promoted by the same single-electron reducing agent in the presence of methanol providing the syn-amino alcohol with a diastereoselectivity of 85:15.	Methanol	172-180	synemin	Homo sapiens	195-198
16212360-11	2005	Close inspection of the correlation lines has suggested that the electron configuration of an essentially pure intermediate-spin Fe(T(i)PrP)L2+ changes from (d(xy), d(yz))3(d(xy))1(d(z)2)1 to (d(xy))2(d(xz), d(yz))2(d(z)2)1 as the axial ligand (L) changes from DMF to MeOH, THF, 2-MeTHF, and then to dioxane.	Methanol	268-272	prion protein	Homo sapiens	136-139
15896194-0	2005	NMR structural analysis of a peptide mimic of the bridging sheet of HIV-1 gp120 in methanol and water.	Methanol	83-91	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	74-79
16110519-1	2005	The structure and dynamics of the retinal chromophore of rhodopsin are investigated systematically in different environments (vacuum, methanol solution, and protein binding pocket) and with different computational approaches (classical, quantum, and hybrid quantum mechanics/molecular mechanics (QM/MM) descriptions).	Methanol	134-142	rhodopsin	Homo sapiens	57-66
16163715-9	2005	These data demonstrate the effectiveness of filter paper as a medium for preserving urinary steroid samples, and the efficiency of methanol as a solvent for eluting E1C and Cr.	Methanol	131-139	small nucleolar RNA, H/ACA box 73B	Homo sapiens	165-168
16329471-1	2005	Fractionation of the MeOH extract of Homaxinella sp., a marine sponge, led to the isolation of a sodium salt of a new brominated FA (1), two new MG (2 and 4), and a new lysoPC (6).	Methanol	21-25	mucin 7, secreted	Homo sapiens	145-156
15871034-3	2005	The electronic (absorption, emission and excitation) spectra of MS1 at room temperature were investigated in pure isooctane as well as in acetonitrile and methanol solutions by the steady-state experiments.	Methanol	155-163	MS	Homo sapiens	64-67
16080212-3	2005	Lysozyme was chosen as a model system for the protein digestion, which has also been prepared in an organic-rich medium with methanol/50 mmol/L NH(4)HCO(3), pH 8.0 (60/40 v/v).	Methanol	125-133	lysozyme	Homo sapiens	0-8
15936963-5	2005	The most favorable conformation in methanol, water, and probably in the polar (or water medicated) enzyme active sites, however, would be the one in which the carbonyl group is in a transoid position and is syn to Hsyn.	Methanol	35-43	synemin	Homo sapiens	207-210
15936963-5	2005	The most favorable conformation in methanol, water, and probably in the polar (or water medicated) enzyme active sites, however, would be the one in which the carbonyl group is in a transoid position and is syn to Hsyn.	Methanol	35-43	RIC8 guanine nucleotide exchange factor B	Homo sapiens	214-218
16121714-6	2005	The results revealed that methanol leaf extract followed by aqueous extract of L. hirta could afford significant protection against CCl4 induced hepatocellular injury.	Methanol	26-34	C-C motif chemokine ligand 4	Rattus norvegicus	132-136
16186915-0	2005	An infrared and inelastic neutron scattering spectroscopic investigation on the interaction of eta-alumina and methanol.	Methanol	111-119	endothelin receptor type A	Homo sapiens	95-98
16186915-1	2005	The industrially important interaction of methanol with an eta-alumina catalyst has been investigated by a combination of infrared spectroscopy (diffuse reflectance and transmission) and inelastic neutron scattering (INS) spectroscopy.	Methanol	42-50	endothelin receptor type A	Homo sapiens	59-62
16178418-1	2005	Methanol extracts of domestic plants of Korea were evaluated as a potential inhibitor of neutral pH optimum and membrane-associated 60 kDa sphingomyelinase (N-SMase) activity.	Methanol	0-8	sphingomyelin phosphodiesterase 2	Homo sapiens	157-164
16075120-4	2005	In contrast, reaction of [Pt2(mu-S)2(PPh3)4] with CuCl2 and NH3 in methanol gave the intensely blue methoxy-bridged dicopper complex [{Pt(2)(mu-S)2(PPh3)4Cu(OMe)}2]2+, isolated as its hexafluorophosphate salt.	Methanol	67-75	caveolin 1	Homo sapiens	37-41
16075120-4	2005	In contrast, reaction of [Pt2(mu-S)2(PPh3)4] with CuCl2 and NH3 in methanol gave the intensely blue methoxy-bridged dicopper complex [{Pt(2)(mu-S)2(PPh3)4Cu(OMe)}2]2+, isolated as its hexafluorophosphate salt.	Methanol	67-75	caveolin 1	Homo sapiens	148-152
16079488-3	2005	The 20, 40 and 60% methanol fractions from the XAD-4 column contained the most insulin sensitizing activities in 3T3-L1 adipocytes.	Methanol	19-27	insulin	Homo sapiens	79-86
16079490-1	2005	The present study was designed to examine whether the methanol extract of Sorbus commixta cortex (MSC) could prevent the development of atherosclerosis through regulating the vascular nitric oxide (NO) and endothelin-1 (ET-1) systems in atherogenic-diet rats.	Methanol	54-62	endothelin 1	Rattus norvegicus	220-224
15968697-5	2005	An increase in the methanol exposure to 0.1 L, at the same temperature, results in the formation of a disordered layer of tilted methoxide: for theta(O)=0.25 ML, C(s)/C1 and intrinsic C1 configurations are present on the surface, whereas for theta(O)&gt; or =0.5 ML, only the former species were identified.	Methanol	19-27	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	167-186
16077099-0	2005	Methanol-dependent gene expression demonstrates that methyl-coenzyme M reductase is essential in Methanosarcina acetivorans C2A and allows isolation of mutants with defects in regulation of the methanol utilization pathway.	Methanol	0-8	coenzyme-B sulfoethylthiotransferase subunit beta	Methanosarcina acetivorans C2A	53-80
16077099-0	2005	Methanol-dependent gene expression demonstrates that methyl-coenzyme M reductase is essential in Methanosarcina acetivorans C2A and allows isolation of mutants with defects in regulation of the methanol utilization pathway.	Methanol	194-202	coenzyme-B sulfoethylthiotransferase subunit beta	Methanosarcina acetivorans C2A	53-80
16027777-6	2005	Through methanol induction, the expression level of Gag reached 120 mg/L.	Methanol	8-16	Pr55(Gag)	Human immunodeficiency virus 1	52-55
16004463-1	2005	Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) melt processed disks and solvent cast films were modified by graft co-polymerization with acrylic acid (AAc) in methanol solution at ambient temperature using gamma irradiation (dose rate of 4.5 kGy/h).	Methanol	164-172	glycine-N-acyltransferase	Homo sapiens	156-159
15960510-1	2005	Carbinols of the Ar-C(OH)R(2) type, Ar being o-isopropylphenyl, exist as stereolabile syn-clinal (sc) and anti-periplanar (ap) atropisomers when R = Me, Et, i-Pr.	Methanol	0-9	synemin	Homo sapiens	86-89
15934732-1	2005	The reaction of fac-[NEt(4)](2)[Re(CO)(3)Br(3)] with (S)-(2-(2"-pyridyl)ethyl)cysteamine, L(1), in methanol leads to the formation of the cationic fac-[Re(CO)(3)(NSN)][Br] complex, 1, with coordination of the nitrogen of the pyridine, the sulfur of the thioether, and the nitrogen of the primary amine.	Methanol	99-107	FA complementation group C	Homo sapiens	16-19
16201387-1	2005	Four new complexes of Ni(II), Cu(II), Zn(II) and Co(III) with HL (HL= N,N"-di-beta-D-glucosylethylenediamine) have been synthesized in methanol solutions.	Methanol	135-143	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	49-56
15907139-6	2005	Treatment of 3-Nd1 and 3-d1 with sodium methoxide results in a selective reaction of the base with the ammonium group to regenerate 2 and 2-d1, respectively.	Methanol	33-49	mitochondrially encoded NADH dehydrogenase 1	Homo sapiens	15-18
16034819-7	2005	The transcriptional regulation of this gene by the carbon source was further confirmed when the alpha-amylase gene from Bacillus subtilis was placed under the control of P(PGK1): higher levels of expression were obtained when cells were grown on glucose as compared to glycerol and methanol.	Methanol	282-290	phosphoglycerate kinase	Saccharomyces cerevisiae S288C	172-176
15987135-10	2005	A simple interpretation of this change in the isotherm curvature at high concentrations when methanol is replaced with acetonitrile as the organic modifier is proposed, based on the structure of the interface between the C18 chains and the bulk mobile phase.	Methanol	93-101	Bardet-Biedl syndrome 9	Homo sapiens	221-224
15930663-1	2005	The title compound, {[N,N-bis(2-pyridylmethyl)amino]ethanol-kappa(3)N,N",N""}tricarbonylrhenium(I) bromide methanol solvate, [Re(C14H17N3O)(CO)3]Br.CH4O, has been prepared in almost quantitative yield by reacting (NEt4)2[Re(CO)3Br3] with the ligand N,N-bispicolyl-2-ethanolamine in refluxing methanol.	Methanol	107-115	tetraspanin 5	Homo sapiens	214-218
16114079-5	2005	The MeOH extract exhibited a potent rat lens aldose reductase (RLAR) inhibition in vitro, and showed a significant inhibition, of not only serum glucose concentrations, but also of sorbitol accumulations in the lens, red blood cells (RBC) and sciatic nerves in STZ-induced diabetic rats.	Methanol	4-8	aldo-keto reductase family 1 member B1	Rattus norvegicus	45-61
15918726-3	2005	Here we show by simple kinetic study of the aggregation process and by scanning electron microscopy (SEM) that when methanol is added to a solution of [60]fullerene in CCl4, spontaneous aggregation starts immediately and the aggregation numbers (n) found to be dependent on the CCl4:CH3OH ratio (v/v) of the medium.	Methanol	116-124	C-C motif chemokine ligand 4	Homo sapiens	168-172
19791408-0	2005	Kinetics of the gas phase HO2 self-reaction: effects of temperature, pressure, water and methanol vapours.	Methanol	89-97	heme oxygenase 2	Homo sapiens	26-29
19791408-1	2005	The kinetics of the gas phase HO2 self-reaction have been studied using flash photolysis of Cl2/CH3OH/O2/N2 mixtures coupled with time-resolved broadband UV absorption spectroscopy.	Methanol	96-101	heme oxygenase 2	Homo sapiens	30-33
15918726-3	2005	Here we show by simple kinetic study of the aggregation process and by scanning electron microscopy (SEM) that when methanol is added to a solution of [60]fullerene in CCl4, spontaneous aggregation starts immediately and the aggregation numbers (n) found to be dependent on the CCl4:CH3OH ratio (v/v) of the medium.	Methanol	116-124	C-C motif chemokine ligand 4	Homo sapiens	278-282
16010942-0	2005	Vapor-phase photo-oxidation of methanol over nano-size titanium dioxide clusters dispersed in MCM-41 host material part 2: catalytic properties and surface transient species.	Methanol	31-39	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	94-97
15914907-3	2005	In the present study, we investigated whether 20 anthocyans dissolved in trifluoroacetic acid (TFA)-MeOH suppressed AhR transformation in a cell-free system and in Hepa-1c1c7 cells.	Methanol	100-104	aryl-hydrocarbon receptor	Mus musculus	116-119
16010942-1	2005	We report in this paper on the ultraviolet-assisted vapor-phase oxidation of methanol at room temperature, with the help of nano-size clusters of titanium dioxide dispersed in an MCM-41 silicate matrix.	Methanol	77-85	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	179-182
16010942-4	2005	The photo-catalytic oxidation of methanol, at concentrations of 0.1 to 1.1 mol% in air, gave rise to formation of CO2 and H2O as products, for both the TiO2/MCM and bulk TiO2 samples.	Methanol	33-41	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	157-160
16010942-7	2005	Thus, the rate of conversion increased progressively with the increase in TiO2 loading from 5 to 21 wt% in TiO2/MCM samples, particularly for the experiments with high concentration of methanol.	Methanol	185-193	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	112-115
15844555-1	2005	The separation of transition metal Ni2+, Cu2+, Co2+, Zn2+, Cd2+ and Fe3+ in methanol was investigated by using different types of organic acids as complexing agents.	Methanol	76-84	CD2 molecule	Homo sapiens	59-62
15808908-5	2005	In methanol, 26RFa adopts a well-defined conformation consisting of an amphipathic alpha-helical structure (Pro4-Arg17), flanked by two N- and C-terminal disordered regions.	Methanol	3-11	pyroglutamylated RFamide peptide	Homo sapiens	13-18
15592826-7	2005	The lipolytic activity of the recombinant LIP1 resulting from the present work is twofold higher than that achieved by a methanol induction system.	Methanol	121-129	sphingosine N-acyltransferase subunit LIP1	Saccharomyces cerevisiae S288C	42-46
15787527-1	2005	An overview of the research of the Olah group over five decades--ranging from synthetic reagents and methods to mechanistic-structural studies to new hydrocarbon chemistry and the development of methanol based fuels and hydrocarbon synthesis--is presented.	Methanol	195-203	oleoyl-ACP hydrolase	Homo sapiens	35-39
15740899-3	2005	cIEF-MS employing 1% Pharmalyte 3-10 and a sheath liquid containing water/methanol/acetic acid (50/49/1) resolved angiotensin I and II (5 microM each, DeltapI=0.2) at an Rs value of 2.29.	Methanol	74-82	angiotensinogen	Homo sapiens	114-134
16108369-8	2005	Expression conditions of human mutant interleukin-2(the codon for cysteine-125 of human IL-2 with alanine; the codon for leucine-18 with methionine; the codon for leucine-19 with serine) in the recombinant Pichia pastoris strain were optimized via test of some factors such as the rate of aeration, the inductive duration, the initial pH and the concentration of methanol.	Methanol	363-371	interleukin 2	Homo sapiens	38-51
16108369-9	2005	The results from tests showed that the most important parameter for efficient expression of interleukin-2 in recombinant Pichia pastoris strain is adequate aeration during methanol induction, and the optimum inductive condition for interleukin-2 expression was: more than 80% aeration, 2 days for induction, the initial pH of 6.0, the final methanol concentration of 1.0%.	Methanol	172-180	interleukin 2	Homo sapiens	92-105
16108369-9	2005	The results from tests showed that the most important parameter for efficient expression of interleukin-2 in recombinant Pichia pastoris strain is adequate aeration during methanol induction, and the optimum inductive condition for interleukin-2 expression was: more than 80% aeration, 2 days for induction, the initial pH of 6.0, the final methanol concentration of 1.0%.	Methanol	341-349	interleukin 2	Homo sapiens	92-105
16108369-9	2005	The results from tests showed that the most important parameter for efficient expression of interleukin-2 in recombinant Pichia pastoris strain is adequate aeration during methanol induction, and the optimum inductive condition for interleukin-2 expression was: more than 80% aeration, 2 days for induction, the initial pH of 6.0, the final methanol concentration of 1.0%.	Methanol	341-349	interleukin 2	Homo sapiens	232-245
16108378-4	2005	After 4 days of methanol induction, the expressed hMn-SOD was up to 32% of the total proteins in the supernatant by SDS-PAGE with specific activity of 247.7 u/mg.	Methanol	16-24	superoxide dismutase 2	Homo sapiens	50-57
16851921-6	2005	This ubiquitous strategy is expected to open a wide avenue for extending ATR surface-enhanced IR absorption spectroscopy to explore molecular adsorption and reactions on technologically important transition metals, as exemplified by successful real-time spectroscopic and electrochemical monitoring of the oxidation of CO at Pd and that of methanol at Pt nanofilm electrodes.	Methanol	340-348	ATR serine/threonine kinase	Homo sapiens	73-76
15740889-3	2005	Searching for inhibitors of MCP-1-induced cell migration from natural sources, we isolated one active compound through active-guided fractionations from the MeOH extracts of Sophora flavescens Ait (Leguminosae).	Methanol	157-161	chemokine (C-C motif) ligand 2	Mus musculus	28-33
15578220-4	2005	Methanol is metabolised in the liver by alcohol dehydrogenase to the toxic metabolites formaldehyde and formic acid.	Methanol	0-8	aldo-keto reductase family 1 member A1	Homo sapiens	40-61
15750225-0	2005	[(1R,2R)-2-Amino-1,2-diphenyl-N-(p-tolylsulfonyl)ethylamido]chloro(eta(6)-ethoxybenzene)ruthenium(II) methanol solvate.	Methanol	102-110	endothelin receptor type A	Homo sapiens	67-70
15578220-6	2005	We report on the use of fomepizole (4-methylpyrazole),a new and potent inhibitor of alcohol dehydrogenase, in a 3-year-old boy after the intake of a toxic amount of methanol.	Methanol	165-173	aldo-keto reductase family 1 member A1	Homo sapiens	84-105
15675846-2	2005	The cyclobutene intermediate 11a and another intermediate 2a were isolated, indicating that PtBr(2) acts as a dual role catalyst: (1) as a transition metal catalyst, it induces the enyne metathesis to produce 11a starting from 1a, and (2) as a Lewis acid catalyst, it facilitates elimination of MeOH from 2a to give the aromatized product 3a.	Methanol	295-299	translocator protein	Homo sapiens	92-96
15762756-8	2005	With increasing methanol concentration from 0.5 to 4.0 M, the Tafel slope of the voltage-current curves (at sigma=0.0), changed from 28 to 91 mV.dec-1, the cell resistance from 2.91 to 0.18 Omega, and the power output from 3 to 18 mW.cm-2.	Methanol	16-24	deleted in esophageal cancer 1	Homo sapiens	145-150
15807253-10	2005	CONCLUSION: The recombinant plasmids pPICZaA-mer and pPICZaA-her could be induced to express the EGFR aimed proteins by methanol in methanol-trophic yeast expression system.	Methanol	120-128	epidermal growth factor receptor	Homo sapiens	97-101
15807253-10	2005	CONCLUSION: The recombinant plasmids pPICZaA-mer and pPICZaA-her could be induced to express the EGFR aimed proteins by methanol in methanol-trophic yeast expression system.	Methanol	132-140	epidermal growth factor receptor	Homo sapiens	97-101
16833436-2	2005	Picosecond time-resolved resonance Raman (ps-TR3) experiments observed that the isodiiodomethane (CH2I-I) photoproduct decayed faster as the concentration of methanol increases, suggesting that isodiiodomethane is reacting with methanol.	Methanol	158-166	thioredoxin reductase 2	Homo sapiens	45-48
15697203-2	2005	We present a microscopic description of the structure and dynamics of PLB in solution and membrane environments, based on 10 ns molecular dynamics simulations of PLB in lipid bilayer and 5 ns simulations in methanol and water, and a water-soluble model of PLB in water.	Methanol	207-215	phospholamban	Homo sapiens	70-73
15697203-4	2005	In the simulations of PLB in methanol and water, the helices were almost perpendicular, with average interhelix angles of 54 +/- 13 degrees and 63 +/-15 degrees , respectively.	Methanol	29-37	phospholamban	Homo sapiens	22-25
15639252-1	2005	The catalytic system Cu(AcO)2-pyridine 1:4 mol% in methanol, slowly catalyses the air oxidation of ascorbic acid to the 2-methyl hemi-ketal of dehydroascorbic acid 5, and hydrogen peroxide.	Methanol	51-59	kallikrein related peptidase 15	Homo sapiens	24-27
15667182-2	2005	In this study, we investigate the electrochemical response of cytochrome c in aqueous/organic solvent mixtures (100% aqueous buffer, 30% acetonitrile, 40% dimethyl sulfoxide, and 50% methanol), reporting the redox potential (E degrees"), enthalpy, and entropy of reduction.	Methanol	183-191	cytochrome c, somatic	Homo sapiens	62-74
15163313-4	2005	Methanol induction resulted in the secretion of active chymase into the Pichia growth media and increasing levels of enzyme were detected in the media for 5 days.	Methanol	0-8	chymase 1	Homo sapiens	55-62
15695903-0	2005	fac-Bromotricarbonyl[2-(2-pyridylmethyl)-2,3-dihydro-1H-isoindol-1-one]rhenium(I) methanol solvate.	Methanol	82-90	FA complementation group C	Homo sapiens	0-3
15714566-2	2005	The stationary phase was 3-(1,8-naphthalimido) propyl-modified silyl silica gel (NAIP) and the best separations were achieved with 4.0 mM citrate buffer (pH 5.0) containing 80% methanol at an applied voltage of 25 kV.	Methanol	177-185	NLR family, apoptosis inhibitory protein 6	Rattus norvegicus	81-85
16035197-1	2005	OBJECTIVE: Methanol is metabolized by alcohol dehydrogenase to formaldehyde, and further to formic acid, which is responsible for the toxicity in methanol poisoning.	Methanol	11-19	aldo-keto reductase family 1 member A1	Homo sapiens	38-59
15588681-11	2005	Thus, the results from this study strongly suggest that the methanol extract of Pereskia bleo may contain bioactive compound(s) that caused breast carcinoma, T-47D cell death by apoptosis mechanism via the activation of caspase-3 and c-myc pathways.	Methanol	60-68	caspase 3	Homo sapiens	220-229
15588681-11	2005	Thus, the results from this study strongly suggest that the methanol extract of Pereskia bleo may contain bioactive compound(s) that caused breast carcinoma, T-47D cell death by apoptosis mechanism via the activation of caspase-3 and c-myc pathways.	Methanol	60-68	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	234-239
15635170-8	2005	Thus, our study suggests that the inhibitions of iNOS, COX-2 expression, and TNF-alpha release by the methanol extract of the semen of Xanthium strumarium L. are achieved by blocking NF-kappaB activation, and that this is also responsible for its anti-inflammatory effects.	Methanol	102-110	nitric oxide synthase 2, inducible	Mus musculus	49-53
15635170-8	2005	Thus, our study suggests that the inhibitions of iNOS, COX-2 expression, and TNF-alpha release by the methanol extract of the semen of Xanthium strumarium L. are achieved by blocking NF-kappaB activation, and that this is also responsible for its anti-inflammatory effects.	Methanol	102-110	tumor necrosis factor	Mus musculus	77-86
15635170-8	2005	Thus, our study suggests that the inhibitions of iNOS, COX-2 expression, and TNF-alpha release by the methanol extract of the semen of Xanthium strumarium L. are achieved by blocking NF-kappaB activation, and that this is also responsible for its anti-inflammatory effects.	Methanol	102-110	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	183-192
15642464-5	2005	When transformed cells were induced with methanol, SDS-PAGE and Western blotting revealed the production of a approximately 6100 Da recombinant CHP (rCHP) expression product.	Methanol	41-49	ras homolog family member V	Rattus norvegicus	144-147
15642464-5	2005	When transformed cells were induced with methanol, SDS-PAGE and Western blotting revealed the production of a approximately 6100 Da recombinant CHP (rCHP) expression product.	Methanol	41-49	ras homolog family member V	Rattus norvegicus	149-153
16035197-1	2005	OBJECTIVE: Methanol is metabolized by alcohol dehydrogenase to formaldehyde, and further to formic acid, which is responsible for the toxicity in methanol poisoning.	Methanol	146-154	aldo-keto reductase family 1 member A1	Homo sapiens	38-59
16035197-2	2005	Fomepizole (4-methylpyrazole) is a potent competitive inhibitor of alcohol dehydrogenase and is used as an antidote to treat methanol poisonings.	Methanol	125-133	aldo-keto reductase family 1 member A1	Homo sapiens	67-88
16259046-5	2005	In addition, a charge-remote fragmentation causing the neutral loss of methanol was observed, which was suggested to be composed by the methyl residue at C-18 and the hydroxyl function located at C-17.	Methanol	71-79	Bardet-Biedl syndrome 9	Homo sapiens	154-158
16399354-3	2005	Beta-glucuronidase activity was assayed using 4-methylumbelliferyl-glucuronide and methanol extracts of rat plasma containing luteolin monoglucuronide as a substrate.	Methanol	83-91	glucuronidase, beta	Rattus norvegicus	0-18
15837125-1	2005	We previously found that the methanol extract of a marine brown alga, Sargassum macrocarpum showed marked nerve growth factor (NGF)-dependent neurite outgrowth promoting activity to PC12D cells.	Methanol	29-37	nerve growth factor	Rattus norvegicus	127-130
16259046-5	2005	In addition, a charge-remote fragmentation causing the neutral loss of methanol was observed, which was suggested to be composed by the methyl residue at C-18 and the hydroxyl function located at C-17.	Methanol	71-79	cytokine like 1	Homo sapiens	196-200
15351776-1	2004	Extracts of bitter melon, soybean, dokudami and welsh onion by 40% methanol increased the accumulation of rhodamine-123 by Caco-2 cells, suggesting that these extracts inhibited P-glycoprotein (P-gp).	Methanol	67-75	ATP binding cassette subfamily B member 1	Homo sapiens	178-192
15859324-10	2005	GS115/Mut+ pPIC9-mMR-1 transformants were selected on minimal methanol medium.	Methanol	62-70	major histocompatibility complex, class I-related	Mus musculus	17-22
15859324-12	2005	The mMR-1 protein was expressed by induction under the concentration of 0.5 % methanol.	Methanol	78-86	major histocompatibility complex, class I-related	Mus musculus	4-9
16019305-9	2004	Studies on the blood enzyme levels of rats showed that while alanine aminotransferase was not affected, aspartate aminotransferase was significantly affected by oral administration of organic solvent-free water and methanol:water (1:1) extractives (P = 0.023 and P = 0.0044), respectively.	Methanol	215-223	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	104-130
15662545-7	2004	Little of the cystatin C produced was in the glycosylated form under fermentation conditions of pH 6, temperature 28 degrees C, methanol only feed, and ammonium hydroxide as a nitrogen source.	Methanol	128-136	cystatin C	Homo sapiens	14-24
15582018-10	2004	The methanol extract (CE), fraction C and CS-1 suppressed paw edema in rats with inhibitory order of magnitude: CS-1&gt;fraction C&gt;CE.	Methanol	4-12	catalase	Rattus norvegicus	112-116
15457571-5	2004	hALR was expressed by GS115 under the induction of 5 mL/L methanol and purified with ultrafiltration after it was analyzed by 15% SDS-PAGE and Western blot.	Methanol	58-66	growth factor, augmenter of liver regeneration	Homo sapiens	0-4
15381075-2	2004	We expressed GFP-tagged human (h)Rad18 in Chinese hamster cells and found that it can be completely extracted from undamaged nuclei by Triton X-100 and methanol.	Methanol	152-160	RAD18 E3 ubiquitin protein ligase	Homo sapiens	33-38
15659783-5	2004	An increase in ERalpha content was observed by Western blot in methanol-treated cells, but this parameter was not affected in butanol-treated cells.	Methanol	63-71	estrogen receptor 1	Homo sapiens	15-22
15351776-1	2004	Extracts of bitter melon, soybean, dokudami and welsh onion by 40% methanol increased the accumulation of rhodamine-123 by Caco-2 cells, suggesting that these extracts inhibited P-glycoprotein (P-gp).	Methanol	67-75	ATP binding cassette subfamily B member 1	Homo sapiens	194-198
15382936-4	2004	When using a methanol:ethanol:water mixture (16:3:1) as the pressure-transmitting medium, two distinct compressibility regions are observed with a dramatic change in the compression mechanism at 4 GPa.	Methanol	13-21	glycophorin A (MNS blood group)	Homo sapiens	197-200
15551374-0	2004	Suppressive effect of inducible nitric oxide synthase (iNOS) expression by the methanol extract of Actinodaphne lancifolia.	Methanol	79-87	nitric oxide synthase 2, inducible	Mus musculus	22-53
15551374-0	2004	Suppressive effect of inducible nitric oxide synthase (iNOS) expression by the methanol extract of Actinodaphne lancifolia.	Methanol	79-87	nitric oxide synthase 2, inducible	Mus musculus	55-59
15452455-0	2004	Suppressive effects of nitric oxide production and inducible nitric oxide synthase (iNOS) gene expression by Calystegia soldanella methanol extract on lipopolysaccharide-activated RAW 264.7 cells.	Methanol	131-139	nitric oxide synthase 2, inducible	Mus musculus	84-88
15452455-2	2004	In this study, to procure the iNOS inhibitors from natural products, we evaluated 57 methanol extracts of natural products including Korean indigenous plants for the inhibition of NO formation on lipopolysaccharide (LPS)-activated mouse macrophage-like RAW 264.7 cells.	Methanol	85-93	nitric oxide synthase 2, inducible	Mus musculus	30-34
15625320-3	2004	In unfolding experiments using methanol, ethanol, 2-propanol, trifluoroethanol (TFE), and sodium dodecyl sulfate (SDS), Tk-MGMT retained its native structure at high concentrations, despite the fact that these chemical solutions affect protein conformations in a number of different ways.	Methanol	31-39	O-6-methylguanine-DNA methyltransferase	Homo sapiens	123-127
15315430-1	2004	Reaction of 1-methyl-2-(4-pentenyl)indole with a catalytic amount of PdCl2(CH3CN)2 (5 mol %) and a stoichiometric amount of CuCl2 (3 equiv) in methanol under CO (1 atm) at room temperature for 30 min led to cyclization/carboalkoxylation to form the corresponding tetrahydrocarbazole in 83% isolated yield as a single regioisomer.	Methanol	143-151	phosducin like 2	Homo sapiens	69-74
15514748-1	2004	The reaction of IrCl3.3H2O with 2-(arylazo)pyridine (HL1) in boiling methanol has afforded [Ir(III)Cl2(L1)(HL1)](1) and [Ir(V)Cl4(HL1)]Cl (2).	Methanol	69-77	intelectin 1	Homo sapiens	53-56
15514748-1	2004	The reaction of IrCl3.3H2O with 2-(arylazo)pyridine (HL1) in boiling methanol has afforded [Ir(III)Cl2(L1)(HL1)](1) and [Ir(V)Cl4(HL1)]Cl (2).	Methanol	69-77	intelectin 1	Homo sapiens	107-110
15514748-1	2004	The reaction of IrCl3.3H2O with 2-(arylazo)pyridine (HL1) in boiling methanol has afforded [Ir(III)Cl2(L1)(HL1)](1) and [Ir(V)Cl4(HL1)]Cl (2).	Methanol	69-77	intelectin 1	Homo sapiens	107-110
15349164-4	2004	The unprecedented 2D structure of [Cd[AlL3](CH3OH)[NO3]2].2CHCl3 and Cd[AlL3](CH3OH)Br2].2CHCl3 .	Methanol	78-83	paired box 5	Homo sapiens	72-76
15281069-6	2004	Apoptosis contributes significantly to methanol neurotoxicity because embryos lacking the cell death genes grim, hid, and reaper have milder CNS defects resulting from methanol exposure than wild-type embryos.	Methanol	39-47	head involution defective	Drosophila melanogaster	113-116
15281069-6	2004	Apoptosis contributes significantly to methanol neurotoxicity because embryos lacking the cell death genes grim, hid, and reaper have milder CNS defects resulting from methanol exposure than wild-type embryos.	Methanol	168-176	head involution defective	Drosophila melanogaster	113-116
15355340-5	2004	Here we report that 48 h after induction with methanol, soluble Gas1p was produced at a yield of approximately 10 mg x L(-1) of medium, and this value was unaffected by the further removal of the serine-rich region or by fusion to a 6 x His tag.	Methanol	46-54	1,3-beta-glucanosyltransferase GAS1	Saccharomyces cerevisiae S288C	64-69
15289186-1	2004	OBJECTIVES: 4-Methylpyrazole (4-MP), an alcohol dehydrogenase (ADH) antagonist, is used for the treatment of ethylene glycol and methanol ingestions.	Methanol	129-137	aldo-keto reductase family 1, member A1 (aldehyde reductase)	Mus musculus	40-61
15307721-2	2004	Detailed analysis of the energy surface of the IMe (X = CH3) ion reveals that the activation barrier of its syn addition to methanol is significantly lower than that of the anti attack.	Methanol	124-132	synemin	Homo sapiens	108-111
15248027-4	2004	Secreted expression of recombinant EKL-His6 was attained by methanol induction and its molecular weight is 43 kD.	Methanol	60-68	1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase HIS6	Saccharomyces cerevisiae S288C	39-43
15273299-2	2004	The mechanisms of reduction of the orthoquinone cofactor (PQQ) of MDH and sGDH involve concerted base-catalyzed proton abstraction from the hydroxyl moiety of methanol or from the 1-hydroxyl of glucose, and hydride equivalent transfer from the substrate to the quinone carbonyl carbon C5 of PQQ.	Methanol	159-167	NADH:ubiquinone oxidoreductase subunit B5	Homo sapiens	74-78
15249941-4	2004	At 77 K, both pmbp and complex have blue emissions in MeOH solutions, which were demonstrated to be phosphorescence by their long decay lifetime (micros).	Methanol	54-58	progesterone receptor membrane component 2	Homo sapiens	14-18
15289186-1	2004	OBJECTIVES: 4-Methylpyrazole (4-MP), an alcohol dehydrogenase (ADH) antagonist, is used for the treatment of ethylene glycol and methanol ingestions.	Methanol	129-137	aldo-keto reductase family 1, member A1 (aldehyde reductase)	Mus musculus	63-66
15330089-12	2004	A methanol volume fraction change of 1% causes a relative decrease of 3.2 and 5.0% of b2 and b3, respectively and a 2% decrease of the saturation capacity q3.	Methanol	2-10	immunoglobulin kappa variable 5-2	Homo sapiens	86-95
15279969-1	2004	The MeOH extract of aerial parts of Flourensia riparia Grisebach (Asteraceae) afforded a sesquiterpene lactone, 4beta-hydroxy-4,10alpha-dimethyl-7alphaH,8alphaH-eudesman-11-ene-8,12-olide, together with septuplinolide, its isomer at positions C-5 and C-10.	Methanol	4-8	homeobox C10	Homo sapiens	251-255
15646010-1	2004	Recombinant human TRAIL was successfully expressed in a secreted form in methyltrophic yeast Pichia pastoris induced by methanol.	Methanol	120-128	TNF superfamily member 10	Homo sapiens	18-23
15986678-7	2004	The chemical anchoring efficiency ofpolymerized PEG and phospholipid molecules, which was calculated by the relative carbon ratio of each surface before and after methanol washing using X-ray photoelectron spectroscopy, was 98%.	Methanol	163-171	progestagen associated endometrial protein	Homo sapiens	48-51
15134917-2	2004	In 10% methanol/water, the one-electron reduction of quinones L1 and L2 to the corresponding semiquinones is shifted to more positive potentials upon addition of one equivalent of Zn(II), Ni(II), Co(II) or Cd(II) and is consistent with formation of a 1:1 complex involving the quinone(N) and adjacent quinone(O).	Methanol	7-15	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	196-202
15154797-8	2004	DFT is used to explore surface intermediates and the transition state in the methanol synthesis reaction (MSR).	Methanol	77-85	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	Homo sapiens	106-109
15093770-0	2004	Hansenula polymorpha Swi1p and Snf2p are essential for methanol utilisation.	Methanol	55-63	Swi1p	Saccharomyces cerevisiae S288C	21-26
15093770-0	2004	Hansenula polymorpha Swi1p and Snf2p are essential for methanol utilisation.	Methanol	55-63	SWI/SNF catalytic subunit SNF2	Saccharomyces cerevisiae S288C	31-36
15093770-1	2004	We have cloned the Hansenula polymorpha SWI1 and SNF2 genes by functional complementation of mutants that are defective in methanol utilisation.	Methanol	123-131	Swi1p	Saccharomyces cerevisiae S288C	40-44
15093770-1	2004	We have cloned the Hansenula polymorpha SWI1 and SNF2 genes by functional complementation of mutants that are defective in methanol utilisation.	Methanol	123-131	SWI/SNF catalytic subunit SNF2	Saccharomyces cerevisiae S288C	49-53
15165272-10	2004	Monoclonal antibody MIB-1 recognized Ki-67 antigen in Papanicolaou-stained cytospins treated by microwave as well as in cytospins that were fixed and stored in methanol without microwave pre-treatment.	Methanol	160-168	MIB E3 ubiquitin protein ligase 1	Homo sapiens	20-25
15115411-2	2004	The substitution of 8 with methanol, ethanol, or succinic acid allowed the access of C-10 CF(3) analogues of beta-artemether, beta-arteether, or artesunate, respectively, in good yields (up to 89%).	Methanol	27-35	gene rich cluster, C10 gene	Mus musculus	85-89
14981078-2	2004	In cells of a pex19 disruption strain (Hppex19), induced on methanol, peroxisome structures were not detectable; peroxisomal matrix proteins accumulated in the cytosol, whereas peroxisomal membrane proteins (PMPs) were mislocalized to the cytosol (Pex3p) and mitochondria (Pex14p) or strongly reduced to undetectable levels (Pex10p).	Methanol	60-68	Pex19p	Saccharomyces cerevisiae S288C	14-19
15033519-4	2004	Adherent cells expressing the MCP-1 receptor CCR2B are treated with MCP-1 in 96-well plates in the presence or absence of inhibitors, fixed and permeabilized with methanol, and then probed with a monoclonal antibody that selectively recognizes the doubly phosphorylated form of p44/42 MAPK.	Methanol	163-171	C-C motif chemokine receptor 2	Homo sapiens	30-44
15116345-5	2004	These results suggest that FLD1 is involved in the detoxification of formaldehyde in methanol metabolism, and Fld1p coordinates the formaldehyde level in methanol-grown cells according to the methanol concentration on growth.	Methanol	85-93	seipin	Saccharomyces cerevisiae S288C	27-31
15116345-5	2004	These results suggest that FLD1 is involved in the detoxification of formaldehyde in methanol metabolism, and Fld1p coordinates the formaldehyde level in methanol-grown cells according to the methanol concentration on growth.	Methanol	154-162	seipin	Saccharomyces cerevisiae S288C	27-31
15116345-5	2004	These results suggest that FLD1 is involved in the detoxification of formaldehyde in methanol metabolism, and Fld1p coordinates the formaldehyde level in methanol-grown cells according to the methanol concentration on growth.	Methanol	154-162	seipin	Saccharomyces cerevisiae S288C	27-31
15072290-2	2004	In a companion paper, we describe the influence of the concentration and the nature of salts dissolved in the mobile phase (methanol:water, 40:60, v/v) on the adsorption behavior of propranolol (R"-NH2+ -R, Cl-) on XTerra-C18.	Methanol	124-132	Bardet-Biedl syndrome 9	Homo sapiens	222-225
15495556-13	2004	Superoxide dismutase SOD1 activity decreased compared with the control group throughout the duration of the experiment from 2212 U/gHb to 1676 U/gHb for ethanol and from 2212 U/gHb to 945 U/gHb for methanol.	Methanol	198-206	superoxide dismutase 1	Rattus norvegicus	21-25
15495556-14	2004	Catalase activity for methanol decreased from 9.1 U/gHb to 5.1 U/gHb, for ethanol to 7.4 U/gHb.	Methanol	22-30	catalase	Rattus norvegicus	0-8
15033519-4	2004	Adherent cells expressing the MCP-1 receptor CCR2B are treated with MCP-1 in 96-well plates in the presence or absence of inhibitors, fixed and permeabilized with methanol, and then probed with a monoclonal antibody that selectively recognizes the doubly phosphorylated form of p44/42 MAPK.	Methanol	163-171	C-C motif chemokine ligand 2	Homo sapiens	30-35
15090302-3	2004	RESULTS: Neurons fixed with -20 degrees Celsius pure acetone and -20 degrees Celsius pure methanol for 5 min presented typical positive staining of NR1 subunit located on the polar membrane of the neurons where the dendrites originated and on the stem of the dendrites.	Methanol	90-98	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	148-151
15108244-0	2004	Developmental toxicity of methanol: Pathogenesis in CD-1 and C57BL/6J mice exposed in whole embryo culture.	Methanol	26-34	CD1 antigen complex	Mus musculus	52-56
15108244-1	2004	BACKGROUND: Methanol causes axial skeleton and craniofacial defects in both CD-1 and C57BL/6J mice during gastrulation, but C57BL/6J embryos are more severely affected.	Methanol	12-20	CD1 antigen complex	Mus musculus	76-80
15108244-2	2004	We evaluated methanol-induced pathogenesis in CD-1 and C57BL/6J embryos exposed during gastrulation in whole embryo culture.	Methanol	13-21	CD1 antigen complex	Mus musculus	46-50
15108244-7	2004	However, protein content in CD-1 embryos was reduced at 3 mg methanol/ml and above, indicating growth retardation.	Methanol	61-69	CD1 antigen complex	Mus musculus	28-32
15098201-1	2004	BACKGROUND: Exposure of pregnant outbred CD-1 mice to methanol during the period of gastrulation results in exencephaly, cleft palate, and cervical vertebra malformations [Rogers and Mole, Teratology 55: 364, 1997], while inbred C57BL/6J mice are sensitive to the teratogenicity of ethanol.	Methanol	54-62	CD1 antigen complex	Mus musculus	41-45
15012118-2	2004	The stereochemistry was determined to be syn in the reaction catalyzed by a dicationic palladium(II) catalyst generated from Pd(MeCN)4(BF4)2 and (S,S)-ip-boxax in the presence of benzoquinone in methanol, while it is mainly anti in the reaction catalyzed by PdCl2(MeCN)2 in the presence of a chloride ion.	Methanol	195-203	synemin	Homo sapiens	41-44
15041240-5	2004	The monomeric 8-coordinate complex [Bi(mtsc)2(NO3)], 4b, which was obtained by slow evaporation in MeOH of the 1.5 hydrates 4a, was depicted with one electron pair of the bismuth(III) atom, two deprotonated mtsc- ligand and one nitrate ion.	Methanol	99-103	NBL1, DAN family BMP antagonist	Homo sapiens	46-49
15111715-2	2004	Reduction of the disulfide bonds of the CM proteins with thioredoxin or dithiothreitol altered their properties so that, like the metabolic proteins, they were insoluble in methanol.	Methanol	173-181	thioredoxin H4-2	Triticum aestivum	57-68
15267448-0	2004	Turbidity determination of the critical exponent eta in the liquid-liquid mixture methanol and cyclohexane.	Methanol	82-90	endothelin receptor type A	Homo sapiens	49-52
15267448-1	2004	The turbidity of the liquid-liquid mixture methanol-cyclohexane has been measured very near its critical point and used to test competing theoretical predictions and to determine the critical correlation-correction exponent eta.	Methanol	43-51	endothelin receptor type A	Homo sapiens	224-227
15038758-4	2004	PtPb, in particular, showed an onset potential that was 100 mV less positive and a peak current density approximately 40 times higher than those observed for Pt in the case of methanol oxidation.	Methanol	176-184	protein tyrosine phosphatase receptor type B	Homo sapiens	0-4
15022721-8	2004	Also, the 60% methanol fraction of CTL suppressed the prostaglandin E2 (PGE2) generation in RAW 264.7 macrophage cells after treatment with lipopolysaccharide (LPS) by as much as the inhibition of 1 mg/kg of indomethacin and this led to the synthesis of PGE2 by COX-2 induction.	Methanol	14-22	cytochrome c oxidase II, mitochondrial	Mus musculus	262-267
15032357-9	2004	RP C18 using methanol-acetic acid (99.5:0.5) as elution solvent provided good recoveries and precision, thus becoming a cheaper but interesting alternative at 0.1-1 ng/ml spiking levels.	Methanol	13-21	protein phosphatase 2 catalytic subunit alpha	Homo sapiens	0-4
14746449-2	2004	The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion.	Methanol	299-307	homeobox C13	Homo sapiens	4-7
14746449-2	2004	The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion.	Methanol	299-307	TBL1X/Y related 1	Homo sapiens	8-11
14753790-1	2004	A simple and fast method for simultaneous separation of nine metal cations Ni2+, Cu2+, Co2+, Zn2+ Cd2+, K+, Na+, Mg2+ and Ca2+, and NH4+ in methanol is reported.	Methanol	140-148	CD2 molecule	Homo sapiens	98-101
14758029-4	2004	Annexin V-positive cells were observed in methanol and DMSO extract-treated, but not PBS extract-treated Hepa-1 and NIH-3T3 cells, suggesting that the lipid-soluble extracts of G. amansii induced apoptosis.	Methanol	42-50	annexin A5	Mus musculus	0-9
15356719-4	2004	The structure of L(5) shows 3 methanol solvent molecules all of which form 2 or 3 hydrogen bonds with triazine nitrogen atoms, amide nitrogen or oxygen atoms, or pyridine nitrogen atoms.	Methanol	30-38	ribosomal protein L5	Homo sapiens	17-21
15356742-1	2004	Reaction of CuX2(X-=Cl- or Br-) with 2 molar equivalents of 3[5]-(2,4,6-trimethylphenyl)pyrazole (HpzMes) in MeOH in the presence of NaOH yields [Cu3X(HpzMes)2(micro-pzMes)3(micro3-OMe)]X (X-=Cl- or Br-).	Methanol	109-113	cut like homeobox 2	Homo sapiens	12-16
15356757-6	2004	in methanol at 50(1)degrees C. The rate of amide cleavage follows the order 1&gt; 2&gt;&gt; 3, L1-3.	Methanol	3-11	immunoglobulin kappa variable 2-4 (pseudogene)	Homo sapiens	95-99