PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
26658801-3	2015	We sought to explore the relationship between HALS and circulating levels of soluble (s) TWEAK and its scavenger receptor sCD163.	hals	46-50	TNF superfamily member 12	Homo sapiens	89-94
26917795-3	2016	Thiazolidinediones are considered a promising treatment for HALS, because they improve insulin sensitivity and increase subcutaneous fat mass.	hals	60-64	insulin	Homo sapiens	87-94
25882366-2	2015	Our aim was to determine whether apelin, apelin receptor, omentin, RBP4, vaspin and visfatin genetic variants and plasma levels are associated with HALS.	hals	148-152	apelin	Homo sapiens	33-39
25882366-2	2015	Our aim was to determine whether apelin, apelin receptor, omentin, RBP4, vaspin and visfatin genetic variants and plasma levels are associated with HALS.	hals	148-152	serpin family A member 12	Homo sapiens	73-79
25882366-2	2015	Our aim was to determine whether apelin, apelin receptor, omentin, RBP4, vaspin and visfatin genetic variants and plasma levels are associated with HALS.	hals	148-152	nicotinamide phosphoribosyltransferase	Homo sapiens	84-92
25882366-9	2015	Circulating RBP4 was significantly higher (p < 0.001) and plasma omentin was significantly lower (p 0.001) in patients with HALS compared to those without HALS; differences in plasma levels of the remaining adipokines were nonsignificant between groups.	hals	127-131	intelectin 1	Homo sapiens	68-75
25882366-10	2015	Circulating RBP4 concentration was predicted independently by the presence of HALS.	hals	78-82	retinol binding protein 4	Homo sapiens	12-16
25882366-13	2015	HALS is associated with higher RBP4 and lower omentin in plasma.	hals	0-4	retinol binding protein 4	Homo sapiens	31-35
25882366-13	2015	HALS is associated with higher RBP4 and lower omentin in plasma.	hals	0-4	intelectin 1	Homo sapiens	46-53
25769096-2	2015	HIV-infected patients frequently develop HIV and highly active antiretroviral treatment-associated lipodystrophy syndrome (HALS), characterized by accumulation of intra-abdominal fat, insulin resistance, and hepatic steatosis.	hals	123-127	insulin	Homo sapiens	184-191
17926640-4	2007	HIV-1 infection, prior to HAART and HALS development, is associated with the upregulation of the mRNA levels of the genes encoding hCNT1, hCNT3 and hENT2.	hals	36-40	solute carrier family 28 member 1	Homo sapiens	131-136
24535275-11	2014	LPS levels were independently predicted by triglycerides (P < 0.001) and hepatitis C virus (P = 0.038), LBP levels by HALS (P < 0.001) and sCD14 levels by age (P = 0.008), current HIV-1 viral load (P = 0.001) and protease inhibitor use (P = 0.018).	hals	121-125	lipopolysaccharide binding protein	Homo sapiens	107-110
24535275-12	2014	CONCLUSIONS: HALS is associated with LBP polymorphism and with higher bacterial translocation.	hals	13-17	lipopolysaccharide binding protein	Homo sapiens	37-40
23706880-3	2013	In HIV/HAART-associated lipodystrophy syndrome (HALS), patients demonstrate fat maldistribution with dyslipidemia, insulin resistance, and other metabolic complications.	hals	48-52	insulin	Homo sapiens	115-122
23706880-5	2013	Two adipokines, leptin and adiponectin, are decreased in patients with HALS and lipoatrophy or lipodystrophy.	hals	71-75	leptin	Homo sapiens	16-22
23706880-5	2013	Two adipokines, leptin and adiponectin, are decreased in patients with HALS and lipoatrophy or lipodystrophy.	hals	71-75	adiponectin, C1Q and collagen domain containing	Homo sapiens	27-38
23706880-6	2013	Further, recent proof-of-concept clinical trials have proven the efficacy of leptin replacement and medications that increase circulating adiponectin levels in improving the metabolic profile of HALS patients.	hals	195-199	leptin	Homo sapiens	77-83
23706880-6	2013	Further, recent proof-of-concept clinical trials have proven the efficacy of leptin replacement and medications that increase circulating adiponectin levels in improving the metabolic profile of HALS patients.	hals	195-199	adiponectin, C1Q and collagen domain containing	Homo sapiens	138-149
21152630-1	2011	Detection and characterisation of structural modifications of a hindered amine light stabiliser (HALS) directly from a polyester-based coil coating have been achieved by desorption electrospray ionisation mass spectrometry (DESI-MS) for the first time.	hals	97-101	desumoylating isopeptidase 2	Homo sapiens	224-228
25700720-8	2015	RESULTS: Serum FGF23 levels were increased in HIV-1-infected patients, but the increase was most marked in those with HALS.	hals	118-122	fibroblast growth factor 23	Homo sapiens	15-20
25700720-9	2015	FGF23 levels showed a strong positive correlation with age, indicators of dyslipidaemia (LDL cholesterol, polyunsaturated fatty acids and monounsaturated fatty acids), HALS parameters (trunk/appendicular fat ratio), insulin resistance (fasting insulin and homeostasis model assessment of insulin resistance) and C-reactive protein.	hals	168-172	fibroblast growth factor 23	Homo sapiens	0-5
25700720-11	2015	CONCLUSIONS: FGF23 levels are increased in HIV-1-infected patients, especially in those with HALS, and this increase is associated with dyslipidaemia, insulin resistance, metabolic syndrome, fat distribution and parameters of inflammation.	hals	93-97	fibroblast growth factor 23	Homo sapiens	13-18
24535275-9	2014	RESULTS: LBP rs2232582 T C polymorphism was significantly associated with HALS (P = 0.01 and P = 0.048 for genotype and allele analyses, respectively).	hals	74-78	lipopolysaccharide binding protein	Homo sapiens	9-12
24535275-10	2014	Plasma levels of LPS (P = 0.009) and LBP (P < 0.001) were significantly higher and sCD14 significantly lower (P < 0.001) in patients with HALS compared with subjects without HALS.	hals	144-148	lipopolysaccharide binding protein	Homo sapiens	37-40
21282454-10	2011	The low-expression TS genotype was associated with the development of HIV/highly active antiretroviral therapy-associated lypodystrophy syndrome (HALS) (OR = 14.0; 95% CI = 2.09 to 108.0; P = 0.0032).	hals	146-150	thymidylate synthetase	Homo sapiens	19-21
21282454-11	2011	Our preliminary data show that polymorphisms in the thymidylate synthase gene are strongly associated with d4T-TP intracellular levels and with development of HALS.	hals	159-163	thymidylate synthetase	Homo sapiens	52-72
18790228-4	2008	METHODS: Between April 2000 and December 2006, 50 patients (23 males) underwent ABO-incompatible kidney transplantation with HALS.	hals	125-129	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Homo sapiens	80-83
18790228-13	2008	CONCLUSIONS: Although meticulous, rigorous surgical technique is essential, HALS is safe and feasible for recipients of ABO-incompatible grafts with tissue weakness and a bleeding tendency because of renal failure and preoperative plasmapheresis.	hals	76-80	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Homo sapiens	120-123
17926640-4	2007	HIV-1 infection, prior to HAART and HALS development, is associated with the upregulation of the mRNA levels of the genes encoding hCNT1, hCNT3 and hENT2.	hals	36-40	solute carrier family 28 member 3	Homo sapiens	138-143
17926640-4	2007	HIV-1 infection, prior to HAART and HALS development, is associated with the upregulation of the mRNA levels of the genes encoding hCNT1, hCNT3 and hENT2.	hals	36-40	solute carrier family 29 member 2	Homo sapiens	148-153
17926640-6	2007	HAART and HALS development are associated with the upregulation of the mRNA levels encoding hCNT2 and hENT1, and further enhancement of hCNT1, hCNT3 and hENT2 gene expression.	hals	10-14	solute carrier family 28 member 2	Homo sapiens	92-97
17926640-6	2007	HAART and HALS development are associated with the upregulation of the mRNA levels encoding hCNT2 and hENT1, and further enhancement of hCNT1, hCNT3 and hENT2 gene expression.	hals	10-14	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	102-107
17926640-6	2007	HAART and HALS development are associated with the upregulation of the mRNA levels encoding hCNT2 and hENT1, and further enhancement of hCNT1, hCNT3 and hENT2 gene expression.	hals	10-14	solute carrier family 28 member 1	Homo sapiens	136-141
17926640-6	2007	HAART and HALS development are associated with the upregulation of the mRNA levels encoding hCNT2 and hENT1, and further enhancement of hCNT1, hCNT3 and hENT2 gene expression.	hals	10-14	solute carrier family 28 member 3	Homo sapiens	143-148
17926640-6	2007	HAART and HALS development are associated with the upregulation of the mRNA levels encoding hCNT2 and hENT1, and further enhancement of hCNT1, hCNT3 and hENT2 gene expression.	hals	10-14	solute carrier family 29 member 2	Homo sapiens	153-158
11289136-5	2001	HA-targeted liposomes (HALs) avidly bound to the CD44-high-expressing B16F10 murine melanoma cell line but not to the CV-1 African green monkey kidney cells, which express CD44 at low levels.	hals	23-27	CD44 antigen	Mus musculus	49-53
11289136-5	2001	HA-targeted liposomes (HALs) avidly bound to the CD44-high-expressing B16F10 murine melanoma cell line but not to the CV-1 African green monkey kidney cells, which express CD44 at low levels.	hals	23-27	CD44 antigen	Mus musculus	172-176
11289136-13	2001	Thus, in both protocols, delivered DOX was significantly more potent than the nonencapsulated DOX in cells expressing high levels of CD44, which suggests that HALs may be a useful targeted drug carrier to treat CD44-expressing tumors.	hals	159-163	CD44 antigen	Mus musculus	133-137
11289136-13	2001	Thus, in both protocols, delivered DOX was significantly more potent than the nonencapsulated DOX in cells expressing high levels of CD44, which suggests that HALs may be a useful targeted drug carrier to treat CD44-expressing tumors.	hals	159-163	CD44 antigen	Mus musculus	211-215
34421784-1	2021	Background and Purpose: This study aimed to analyze the association between hyperattenuated lesions (HALs) and postoperative intracranial hemorrhage (IH) and predict perioperative IH through quantitative analysis of HALs in acute ischemic stroke (AIS) with anterior large vessel occlusion (LVO) after endovascular therapy (ET).	hals	216-220	major facilitator superfamily domain containing 11	Homo sapiens	323-325
34421784-11	2021	Conclusions: Patients with HALs after ET are more likely to have perioperative IH.	hals	27-31	major facilitator superfamily domain containing 11	Homo sapiens	38-40
32707319-11	2020	Therefore, boiling and domestic filtering of tap water may be recommended for the removal of HALs prior to consuming tap water.	hals	93-97	nuclear RNA export factor 1	Homo sapiens	45-48
32739696-4	2020	This study evaluated CX3R-type DBP precursors removal from rainwater by conventional drinking water treatments and the corresponding decrease of CX3R-type DBP (trihalomethanes (THMs), haloaldehydes (HALs), haloacetonitriles (HANs) and haloacetamides (HAMs)) formation and toxicity during the subsequent chlor(am)ination.	hals	199-203	D-box binding PAR bZIP transcription factor	Homo sapiens	31-34