PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
31104300-10	2019	ADRB2 was directly targeted by miR-15a-5p, and miR-15a-5p inhibited IL-13-induced expression of GM-CSF, eotaxin, and MUC5AC in NECs.	15a	35-38	adrenoceptor beta 2	Homo sapiens	0-5
33171189-5	2020	Treatment of diabetic mice with 15a inhibited diabetes-induced renal fibrosis, NF-kappaB activation, and upregulation of proinflammatory cytokines.	15a	32-35	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	79-88
32212891-7	2020	miR-15a-5p targeted NR2B and negatively regulated its expression.	15a	4-7	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	20-24
28246398-6	2017	Treatment with 15a reduced the amount of circulating CCR2+ monocytes and the size of the atherosclerotic plaques in both the carotid artery and the aortic root.	15a	15-18	chemokine (C-C motif) receptor 2	Mus musculus	53-57
28657744-3	2017	Furthermore, the N-methyl compound (+)-15a, which displayed an EC50 of 23 nM in the calcium flux assay while showing no beta-arrestin recruitment activity, is the most functionally selective 5-HT2C agonist reported to date.	15a	39-42	5-hydroxytryptamine receptor 2C	Homo sapiens	191-197
20580563-8	2010	In addition, intravenous administration of 15a to castrated male rat suppressed plasma LH level, which indicates the possibility of a small molecule GPR54 antagonist as a novel drug for sex-hormone dependent diseases.	15a	43-46	KISS1 receptor	Rattus norvegicus	149-154
35085550-8	2022	In addition to MEK1, ERK1 was subsequently found to be targeted by miR-15a/16, with DOX-induced miR-15a/16 reducing total ERK1 levels in T cells.	15a	100-103	mitogen-activated protein kinase 3	Mus musculus	21-25
35085550-8	2022	In addition to MEK1, ERK1 was subsequently found to be targeted by miR-15a/16, with DOX-induced miR-15a/16 reducing total ERK1 levels in T cells.	15a	100-103	microRNA 15a	Mus musculus	67-74
35085550-8	2022	In addition to MEK1, ERK1 was subsequently found to be targeted by miR-15a/16, with DOX-induced miR-15a/16 reducing total ERK1 levels in T cells.	15a	100-103	mitogen-activated protein kinase 3	Mus musculus	122-126
24032466-9	2014	Docking studies for 14c and 15a with COX-2 showed good binding profile.	15a	28-31	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	37-42
24189055-6	2013	However, use of selective caspase inhibitors revealed that the caspase-8-dependent pathway is the major contributor to 15a-induced apoptosis.	15a	119-122	caspase 8	Homo sapiens	63-72