PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11471753-2	2001	Bisphenol A, bisphenol B, and 3,4"-(1-methylethylidene)bisphenol were converted to their monoquinone derivatives in the presence of tyrosinase at 25 degrees C at pH 6.5, but not to the bisquinone derivatives under these conditions.	bpb	13-24	tyrosinase	Homo sapiens	132-142
34411698-6	2021	Moreover, locomotor activity of larvae was decreased, and the transcription of genes (e.g., elavl3, gap43, zn5, alpha-tubulin, syn2a and mbp) related to neuronal development were inhibited after exposure to BPB.	bpb	207-210	ELAV like neuron-specific RNA binding protein 3	Danio rerio	92-98
33940105-8	2021	BPB markedly increased the phosphorylation of AKT1, AKT2, and ERK1/2 at 200 mg/kg.	bpb	0-3	AKT serine/threonine kinase 1	Rattus norvegicus	46-50
33940105-8	2021	BPB markedly increased the phosphorylation of AKT1, AKT2, and ERK1/2 at 200 mg/kg.	bpb	0-3	AKT serine/threonine kinase 2	Rattus norvegicus	52-56
33940105-8	2021	BPB markedly increased the phosphorylation of AKT1, AKT2, and ERK1/2 at 200 mg/kg.	bpb	0-3	mitogen activated protein kinase 3	Rattus norvegicus	62-68
34411698-6	2021	Moreover, locomotor activity of larvae was decreased, and the transcription of genes (e.g., elavl3, gap43, zn5, alpha-tubulin, syn2a and mbp) related to neuronal development were inhibited after exposure to BPB.	bpb	207-210	growth associated protein 43	Danio rerio	100-105
34411698-6	2021	Moreover, locomotor activity of larvae was decreased, and the transcription of genes (e.g., elavl3, gap43, zn5, alpha-tubulin, syn2a and mbp) related to neuronal development were inhibited after exposure to BPB.	bpb	207-210	synapsin IIa	Danio rerio	127-132
34411698-6	2021	Moreover, locomotor activity of larvae was decreased, and the transcription of genes (e.g., elavl3, gap43, zn5, alpha-tubulin, syn2a and mbp) related to neuronal development were inhibited after exposure to BPB.	bpb	207-210	myelin basic protein a	Danio rerio	137-140
33392205-10	2020	Besides, the pattern of estrogen receptor alpha (ERalpha) dynamics was disrupted with a mass gathering on the spindle in BPB-exposed oocytes.	bpb	121-124	estrogen receptor 1 (alpha)	Mus musculus	24-47
35390692-5	2022	Moreover, an estrogen receptor (ER) antagonist ICI 182780 antagonized BPB-caused up-regulation of ovary-biased gene and vtgb1 expression to some degree, indicating that the effects of BPB on X. laevis testis differentiation could be partly mediated by ER.	bpb	70-73	vitellogenin B1 L homeolog	Xenopus laevis	120-125
35390692-5	2022	Moreover, an estrogen receptor (ER) antagonist ICI 182780 antagonized BPB-caused up-regulation of ovary-biased gene and vtgb1 expression to some degree, indicating that the effects of BPB on X. laevis testis differentiation could be partly mediated by ER.	bpb	184-187	vitellogenin B1 L homeolog	Xenopus laevis	120-125
33392205-10	2020	Besides, the pattern of estrogen receptor alpha (ERalpha) dynamics was disrupted with a mass gathering on the spindle in BPB-exposed oocytes.	bpb	121-124	estrogen receptor 1 (alpha)	Mus musculus	49-56
32387340-3	2020	We applied next generation sequencing (NGS) with the estrogen receptor alpha (ERalpha) positive human breast cancer cell line MCF-7 treated with 17-beta-estradiol (E2), bisphenol A (BPA), bisphenol B (BPB), bisphenol Z (BPZ) and tetramethyl bisphenol A (4MeBPA).	bpb	188-199	estrogen receptor 1	Homo sapiens	78-85
32387340-7	2020	We further confirmed the binding, activation and proliferative effect of BPA, BPB, BPZ, and 4MeBPA on ERalpha.	bpb	78-81	estrogen receptor 1	Homo sapiens	102-109
28858478-0	2017	Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway.	bpb	17-28	G protein-coupled estrogen receptor 1	Homo sapiens	82-117
29940534-4	2018	BPA alternatives such as bisphenol B (BPB), bisphenol F (BPF), and bisphenol S (BPS) have a similar chemical structure and binding ability for estrogen receptor (ER), which shows toxicological effects in animals.	bpb	25-36	estrogen receptor 1	Rattus norvegicus	143-160
29940534-4	2018	BPA alternatives such as bisphenol B (BPB), bisphenol F (BPF), and bisphenol S (BPS) have a similar chemical structure and binding ability for estrogen receptor (ER), which shows toxicological effects in animals.	bpb	25-36	estrogen receptor 1	Rattus norvegicus	162-164
29940534-4	2018	BPA alternatives such as bisphenol B (BPB), bisphenol F (BPF), and bisphenol S (BPS) have a similar chemical structure and binding ability for estrogen receptor (ER), which shows toxicological effects in animals.	bpb	38-41	estrogen receptor 1	Rattus norvegicus	143-160
29940534-4	2018	BPA alternatives such as bisphenol B (BPB), bisphenol F (BPF), and bisphenol S (BPS) have a similar chemical structure and binding ability for estrogen receptor (ER), which shows toxicological effects in animals.	bpb	38-41	estrogen receptor 1	Rattus norvegicus	162-164
28858478-4	2017	Here, using a SKBR3 cell-based fluorescence competitive binding assay, we found six BPA analogues bound to GPER directly, with bisphenol AF (BPAF) and bisphenol B (BPB) displaying much higher (~9-fold) binding affinity than BPA.	bpb	151-162	G protein-coupled estrogen receptor 1	Homo sapiens	107-111
28858478-4	2017	Here, using a SKBR3 cell-based fluorescence competitive binding assay, we found six BPA analogues bound to GPER directly, with bisphenol AF (BPAF) and bisphenol B (BPB) displaying much higher (~9-fold) binding affinity than BPA.	bpb	164-167	G protein-coupled estrogen receptor 1	Homo sapiens	107-111
28858478-8	2017	Moreover, based on the results of Boyden chamber and wound-healing assays, BPAF and BPB displayed higher activity in promoting GPER mediated SKBR3 cell migration than BPA with the LOEC of 100 nM.	bpb	84-87	G protein-coupled estrogen receptor 1	Homo sapiens	127-131
28858478-9	2017	Overall, we found two BPA analogues BPAF and BPB could exert higher estrogenic effects than BPA via GPER pathway at nanomolar concentrations.	bpb	45-48	G protein-coupled estrogen receptor 1	Homo sapiens	100-104
20467186-8	2010	Like BPA, bisphenol F (BPF), bisphenol E (BPE), and bisphenol B (BPB) decreased the amounts of intracellular and medium adiponectin.	bpb	52-63	adiponectin, C1Q and collagen domain containing	Homo sapiens	120-131
28894220-2	2017	Saturation transfer difference (STD) NMR-based binding studies were performed to investigate the binding potential of two bisphenol representatives, namely, bisphenol B (BPB) and bisphenol E (BPE), toward human serum albumin (HSA).	bpb	157-168	albumin	Homo sapiens	211-224
28894220-2	2017	Saturation transfer difference (STD) NMR-based binding studies were performed to investigate the binding potential of two bisphenol representatives, namely, bisphenol B (BPB) and bisphenol E (BPE), toward human serum albumin (HSA).	bpb	170-173	albumin	Homo sapiens	211-224
20467186-8	2010	Like BPA, bisphenol F (BPF), bisphenol E (BPE), and bisphenol B (BPB) decreased the amounts of intracellular and medium adiponectin.	bpb	65-68	adiponectin, C1Q and collagen domain containing	Homo sapiens	120-131