PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
6304055-1	1983	This uncoupling is consistent with the preferential binding of two perchlorate anions to the globular form(s) cytochrome c.	perchlorate	67-78	cytochrome c, somatic	Equus caballus	110-122
6688254-6	1983	These differences are again seen by exposure of E2R to chaotropic salts such as SCN-, ClO-4 and NO3- as well as to putative modifiers of receptor amino acids, ie, iodoacetamide, 1,2 cyclohexanedione, and Rose Bengal.	perchlorate	86-91	DNA segment, E2R	Mus musculus	48-51
6168154-5	1981	The possibility that an inhibitor specific for G6PDH was generated in ClO4- - treated rat thyroids was excluded.	perchlorate	70-74	glucose-6-phosphate dehydrogenase	Rattus norvegicus	47-52
6168154-6	1981	The activity of ODC was greatly increased by both ClO4- and MTU, the increase being significant as early as on the second day of treatment.	perchlorate	50-54	ornithine decarboxylase 1	Rattus norvegicus	16-19
6168154-8	1981	These results suggest that ClO4- acts directly on the thyroid to suppress specifically the stimulatory effect of TSH on G6PDH activity and possibly on polyamine accumulation.	perchlorate	27-31	glucose-6-phosphate dehydrogenase	Rattus norvegicus	120-125
6254769-0	1980	Perchlorate binding to cytochrome c: a magnetic and optical study.	perchlorate	0-11	cytochrome c, somatic	Homo sapiens	23-35
6257522-5	1980	A lower limit of 0.15 min-1 for the binding rate constant in the uninhibited gland was estimated from the observations in one subject who demonstrated a small perchlorate discharge.	perchlorate	159-170	CD59 molecule (CD59 blood group)	Homo sapiens	22-27
6254769-2	1980	The effects of perchlorate on cytochrome c have been investigated by 1H and 35Cl NMR, electron paramagnetic resonance and optical spectroscopy.	perchlorate	15-26	cytochrome c, somatic	Homo sapiens	30-42
6254769-12	1980	The effects of perchlorate on cytochrome c are due to specific binding of this ion.	perchlorate	15-26	cytochrome c, somatic	Homo sapiens	30-42
33955747-12	2021	The complexes demonstrate turnover frequencies (TOF) of 3800 s-1 for 1, 5400 s-1 for 2, and 8800 s-1 for 3 in MeCN (3 mL) containing 0.1 M [n-Bu4N](ClO4) in the presence of HOAc (145 equiv) at overpotentials of ca.	perchlorate	148-152	hypoacusis 2 (autosomal recessive)	Homo sapiens	173-177
6769499-7	1980	For the simple electrolyte ions studied, the rate of iron release from diferric-transferrin increases in accordance with the lyotropic series: SO4 2- less than HCO-2 less than Cl- less than ClO4- and Na+ less than Li+.	perchlorate	190-194	transferrin	Homo sapiens	80-91
16653749-0	1942	SOME RESPONSES OF THE BEAN PLANT TO CHLORATE AND PERCHLORATE IONS.	perchlorate	49-60	brain expressed associated with NEDD4 1	Homo sapiens	22-26
199271-1	1977	In an attempt to understand the specific effect of inorganic protein denaturants, lithium cation and perchlorate anion, upon the molecular conformation of bovine alpha-lactalbumin and to characterize the denatured states of the protein and the denaturation processes, themodynamic studies on the reversible unfolding of the protein in the presence of lithium chloride, lithium perchlorate and sodium perchlorate were made by means of circular dichroism and ultraviolet absorption measurements.	perchlorate	101-112	lactalbumin alpha	Bos taurus	162-179
192541-1	1977	Perchlorate treatment of mice increased by 1.5-2-fold the thyroid secretory response to TSH, hCG and LATS, in the McKenzie bioassay.	perchlorate	0-11	chorionic gonadotropin subunit beta 5	Homo sapiens	93-96
192203-6	1977	Trichloroacetate and perchlorate at very low concentrations were able to dissociate the protein kinase and modulate its binding characteristics as well.	perchlorate	21-32	protein kinase cAMP-activated catalytic subunit beta	Bos taurus	88-102
33485237-2	2021	And then, the step-feeding distribution ratio of the heterotrophic perchlorate reduction unit (HPR unit) was optimized to achieve efficient removal of high concentration perchlorate.	perchlorate	67-78	haptoglobin-related protein	Homo sapiens	95-98
33485237-2	2021	And then, the step-feeding distribution ratio of the heterotrophic perchlorate reduction unit (HPR unit) was optimized to achieve efficient removal of high concentration perchlorate.	perchlorate	170-181	haptoglobin-related protein	Homo sapiens	95-98
33881845-5	2021	Moisture, fiber, and fat in foods were identified as critical factors affecting perchlorate bioavailability (correlation r = 0.71, 0.52, and -0.67, respectively).	perchlorate	80-91	FAT atypical cadherin 1	Homo sapiens	21-24
33948439-4	2021	The perchlorate"s effects were detected by histopathological examination, aromatase/CYP19 A1 activity, reactive oxygen species production (ROS), and Caspase-3 expression.	perchlorate	4-15	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	74-83
33948439-7	2021	Despite the slight induction effect of the lowest perchlorate concentration (5 mug/L) on caspase 3 expression, CYP 19 activity, and ROS generation, it did not affect placental cellular viability.	perchlorate	50-61	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	111-117
33948439-4	2021	The perchlorate"s effects were detected by histopathological examination, aromatase/CYP19 A1 activity, reactive oxygen species production (ROS), and Caspase-3 expression.	perchlorate	4-15	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	84-92
33948439-8	2021	Conclusion: This study suggested that perchlorate could modulate aromatase activity and placental cytotoxicity.	perchlorate	38-49	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	65-74
33948439-4	2021	The perchlorate"s effects were detected by histopathological examination, aromatase/CYP19 A1 activity, reactive oxygen species production (ROS), and Caspase-3 expression.	perchlorate	4-15	caspase 3	Homo sapiens	149-158
33948439-7	2021	Despite the slight induction effect of the lowest perchlorate concentration (5 mug/L) on caspase 3 expression, CYP 19 activity, and ROS generation, it did not affect placental cellular viability.	perchlorate	50-61	caspase 3	Homo sapiens	89-98
33522808-1	2021	Gas-phase tetrapositively charged M(HMNTA)24+ (M = Zr, Hf, Th, and U) ions were generated via electrospray ionization of the M(ClO4)4 and N,N,N",N",N"",N""-hexamethylnitrilotriacetamide (HMNTA) mixtures in acetonitrile.	perchlorate	127-131	gastrin	Homo sapiens	0-3
33187716-3	2021	However, the adsorption capacity for ClO4- by several crosslinked CSBs has been shown to be low.	perchlorate	37-41	CXADR like membrane protein	Homo sapiens	66-70
33187716-7	2021	ECH crosslinking also enhances hydrophilicity of CSBs to allow for increased adsorption for ClO4-.	perchlorate	92-96	CXADR like membrane protein	Homo sapiens	49-53
33879962-6	2021	On the other hand, Mg(ClO4)2 significantly accelerated the reaction between AscH2 and beta-CD-solubilized DPPH  (DPPH /beta-CD) in phosphate buffer (0.05 M, pH 6.5), although the addition of 0.05 M Mg(ClO4)2 to the AscH2-DPPH /beta-CD system in phosphate buffer (0.05 M, pH 7.0) resulted in the change in pH of the phosphate buffer to be 6.5.	perchlorate	22-26	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	86-93
33879962-6	2021	On the other hand, Mg(ClO4)2 significantly accelerated the reaction between AscH2 and beta-CD-solubilized DPPH  (DPPH /beta-CD) in phosphate buffer (0.05 M, pH 6.5), although the addition of 0.05 M Mg(ClO4)2 to the AscH2-DPPH /beta-CD system in phosphate buffer (0.05 M, pH 7.0) resulted in the change in pH of the phosphate buffer to be 6.5.	perchlorate	22-26	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	119-126
33879962-6	2021	On the other hand, Mg(ClO4)2 significantly accelerated the reaction between AscH2 and beta-CD-solubilized DPPH  (DPPH /beta-CD) in phosphate buffer (0.05 M, pH 6.5), although the addition of 0.05 M Mg(ClO4)2 to the AscH2-DPPH /beta-CD system in phosphate buffer (0.05 M, pH 7.0) resulted in the change in pH of the phosphate buffer to be 6.5.	perchlorate	22-26	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	119-126
33879962-6	2021	On the other hand, Mg(ClO4)2 significantly accelerated the reaction between AscH2 and beta-CD-solubilized DPPH  (DPPH /beta-CD) in phosphate buffer (0.05 M, pH 6.5), although the addition of 0.05 M Mg(ClO4)2 to the AscH2-DPPH /beta-CD system in phosphate buffer (0.05 M, pH 7.0) resulted in the change in pH of the phosphate buffer to be 6.5.	perchlorate	201-205	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	86-93
32451489-0	2020	Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate.	perchlorate	64-75	solute carrier family 5 member 5	Homo sapiens	35-51
33392613-6	2021	A nematode strain (agIs219) containing an integrated copy of the significantly overexpressed t24b8.5 gene promoter followed by a GFP reporter gene was shown to fluoresce in a perchlorate dose dependent manner with a limit of detection (LOD) of 0.5 mg mL-1.	perchlorate	175-186	L1 cell adhesion molecule	Mus musculus	251-255
33038323-4	2021	Based on its relative resistance to perchlorate, the NIS protein from minke whale appeared to be the superior candidate reporter gene.	perchlorate	36-47	solute carrier family 5 member 5	Homo sapiens	53-56
33038323-5	2021	SPECT and PET imaging studies in nude mice challenged with NIS-encoding adeno-associated virus (AAV)-9 vectors confirmed that minke whale NIS, in contrast to human and endogenous mouse NIS, continues to function as a reliable reporter even when background radiotracer uptake by endogenous NIS is blocked by perchlorate.	perchlorate	307-318	solute carrier family 5 member 5	Homo sapiens	138-141
33038323-5	2021	SPECT and PET imaging studies in nude mice challenged with NIS-encoding adeno-associated virus (AAV)-9 vectors confirmed that minke whale NIS, in contrast to human and endogenous mouse NIS, continues to function as a reliable reporter even when background radiotracer uptake by endogenous NIS is blocked by perchlorate.	perchlorate	307-318	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	138-141
33038323-5	2021	SPECT and PET imaging studies in nude mice challenged with NIS-encoding adeno-associated virus (AAV)-9 vectors confirmed that minke whale NIS, in contrast to human and endogenous mouse NIS, continues to function as a reliable reporter even when background radiotracer uptake by endogenous NIS is blocked by perchlorate.	perchlorate	307-318	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	138-141
33094791-2	2020	Anion exchange of [PdL2](NO3)2 with X- (X- = BF4-, ClO4-, and PF6-) changes the skeleton into a cage of [(X)@Pd2L4](X)3.	perchlorate	51-55	programmed cell death 1 ligand 2	Homo sapiens	19-23
32740759-6	2022	Our results show that perchlorate was detected in soil (median: 22.2 ng g-1), drinking water (median: 3.0 ng mL-1), fruits (median: 0.91 ng g-1 fresh weight [FW]), lettuce (median: 5.0 ng g-1 FW) and chard (median: 4.15 ng g-1 FW).	perchlorate	22-33	L1 cell adhesion molecule	Mus musculus	109-113
32740759-7	2022	Interestingly, perchlorate concentrations detected in drinking water from three regions (Serena, Copiapo and Illapel) exceeded the USEPA interim drinking water health advisory level of 15 ng mL-1.	perchlorate	15-26	L1 cell adhesion molecule	Mus musculus	191-195
32458917-6	2020	Analysis of reaction mixtures leading to the formation of the MBBP analogs [(MBBP)Ni(R2-1,3-diketonate)]X (X = ClO4: 5: R = CH3; 6: R = C(CH3)3; 7-ClO4: R = Ph; X = Cl: 7-Cl: R = Ph) using 1H NMR and ESI-MS revealed the presence of [(MBBP)2Ni](ClO4)2 (8).	perchlorate	111-115	splicing factor 1	Homo sapiens	62-66
32458917-6	2020	Analysis of reaction mixtures leading to the formation of the MBBP analogs [(MBBP)Ni(R2-1,3-diketonate)]X (X = ClO4: 5: R = CH3; 6: R = C(CH3)3; 7-ClO4: R = Ph; X = Cl: 7-Cl: R = Ph) using 1H NMR and ESI-MS revealed the presence of [(MBBP)2Ni](ClO4)2 (8).	perchlorate	147-151	splicing factor 1	Homo sapiens	62-66
32451489-1	2020	The Na+/I- symporter (NIS), the plasma membrane protein that actively transports I- (stoichiometry 2Na+:1I-) in thyroid physiology and radioiodide-based thyroid cancer treatment, also transports the environmental pollutant perchlorate (stoichiometry 1Na+:1ClO4-), which competes with I- for transport.	perchlorate	223-234	solute carrier family 5 member 5	Homo sapiens	4-20
32451489-1	2020	The Na+/I- symporter (NIS), the plasma membrane protein that actively transports I- (stoichiometry 2Na+:1I-) in thyroid physiology and radioiodide-based thyroid cancer treatment, also transports the environmental pollutant perchlorate (stoichiometry 1Na+:1ClO4-), which competes with I- for transport.	perchlorate	223-234	solute carrier family 5 member 5	Homo sapiens	22-25
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	spindlin 1	Homo sapiens	163-167
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	spindlin 1	Homo sapiens	210-214
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	sperm associated antigen 17	Homo sapiens	254-257
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	NBL1, DAN family BMP antagonist	Homo sapiens	267-270
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	spindlin 1	Homo sapiens	210-214
32208375-2	2020	Isostructural ClO4- and BF4- salts (1) and (2) each have two unique Mn3+ sites which follow different thermal evolution pathways resulting in a crossover from the spin quintet form at room temperature to a 1:1 spin triplet:quintet ratio below 150 K. The PF6- (3) and NO3- (4) salts which each have one unique Mn3+ site show a complete conversion from spin quintet to spin triplet over the same temperature range.	perchlorate	14-18	spindlin 1	Homo sapiens	210-214
31875569-1	2020	Nitrate (NO3-) affected perchlorate (ClO4-) reduction in a membrane batch biofilm reactor (MBBR), even though the electron donor, CH4, was available well in excess of its demand.	perchlorate	24-35	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
32084174-2	2020	NIS also transports other monovalent anions such as tetrafluoroborate (BF4-), pertechnetate (TcO4-), and thiocyanate (SCN-), and is competitively inhibited by perchlorate (ClO4-).	perchlorate	159-170	solute carrier family 5 member 5	Homo sapiens	0-3
32084174-2	2020	NIS also transports other monovalent anions such as tetrafluoroborate (BF4-), pertechnetate (TcO4-), and thiocyanate (SCN-), and is competitively inhibited by perchlorate (ClO4-).	perchlorate	172-176	solute carrier family 5 member 5	Homo sapiens	0-3
32084174-8	2020	Whereas each of the three proteins that were analyzed in detail concentrated iodide to a similar degree, their sensitivity to perchlorate inhibition varied significantly: minke whale NIS was the least impacted by perchlorate inhibition (IC50 = 4.599 muM), zebrafish NIS was highly sensitive (IC50 = 0.081 muM), and human NIS showed intermediate sensitivity (IC50 = 1.566 muM).	perchlorate	126-137	solute carrier family 5 member 5	Homo sapiens	183-186
31837793-10	2020	Results showed that at a dosing of 4 ppm of ECW, both chlorate and perchlorate concentrations in milk (<0.002 mg/kg) were low, and no deleterious effects on milk production or milk chemical composition were observed.	perchlorate	67-78	Weaning weight-maternal milk	Bos taurus	97-101
31659234-4	2020	Previously, we showed pure culture SRM adaptation to perchlorate stress through mutation of the sulfate adenylyltransferase, a central enzyme in the sulfate reduction pathway.	perchlorate	53-64	3'-phosphoadenosine 5'-phosphosulfate synthase 1	Homo sapiens	96-123
31761036-0	2020	HPLC-ICPMS/MS shows a significant advantage over HPLC-ICPMS for the determination of perchlorate in ground, tap, and river water.	perchlorate	85-96	nuclear RNA export factor 1	Homo sapiens	108-111
31761036-5	2020	We report a rapid and simple method for perchlorate determination in ground, tap, and river water and we show that the ICPMS/MS offers as a chromatographic detector at least 10-fold improvement in the detection limit relative to single quadrupole ICPMS.	perchlorate	40-51	nuclear RNA export factor 1	Homo sapiens	77-80
31348636-11	2019	Anion adsorption during batch and flow-through test with the ClO4-roseLDH (mean particle diameter ~ 38 mum) in a packed bed showed good uptake of HPO42- and NO3- from aqueous solutions.	perchlorate	61-65	NBL1, DAN family BMP antagonist	Homo sapiens	157-160
31342029-3	2019	Structural and magnetic data also indicate that co-crystallization of complexes 2 and 3 with 0.5 equivalents of ethanol yields the high spin S = 2 forms of the perchlorate and tetrafluoroborate solvates [Mn(napsal2323)]ClO4 0.5(C2H5OH), 2 0.5EtOH and [Mn(napsal2323)]BF4 0.5(C2H5OH), 3 0.5EtOH.	perchlorate	160-171	spindlin 1	Homo sapiens	136-140
31393480-5	2019	The complexes displayed a quasi-reversible Co(i)/Co(ii) redox couple at ~-1.1 V and an irreversible Co(ii)/Co(iii) couple at ~1.3 V vs. Ag/AgCl in DMF-0.1 M [Bun4N](ClO4).	perchlorate	165-169	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	100-106
31141766-4	2019	Further it was found that the sensor is highly selective towards fluoride over other anions including chloride, bromide, iodide, nitrate, borate, perchlorate and can quantitatively detect fluoride at ppb level with a limit of detection of 0.02 mg/ L or 20 ppb.	perchlorate	146-157	histatin 1	Homo sapiens	200-203
31094188-7	2019	Importantly, the sensitivity toward cations was strongly dependent on counteranions and increased as follows: NO3- < Br- < CF3SO3- < ClO4- << SCN-.	perchlorate	142-146	NBL1, DAN family BMP antagonist	Homo sapiens	110-113
31296047-6	2019	Forty-two animals were imaged with 99mTcO4- +- the selective NIS inhibitor perchlorate on day 10, to ascertain specificity of radiotracer uptake.	perchlorate	75-86	solute carrier family 5 member 5	Homo sapiens	61-64
31296047-11	2019	Perchlorate treatment significantly reduced 99mTcO4- uptake in AAV9-hNIS-treated muscles, demonstrating uptake specificity.	perchlorate	0-11	solute carrier family 5 member 5	Homo sapiens	68-72
31094188-7	2019	Importantly, the sensitivity toward cations was strongly dependent on counteranions and increased as follows: NO3- < Br- < CF3SO3- < ClO4- << SCN-.	perchlorate	142-146	sorcin	Homo sapiens	157-160
30826543-2	2019	Athena C18-WP column was used to separate and analyze perchlorate.	perchlorate	54-65	Bardet-Biedl syndrome 9	Homo sapiens	7-10
31082209-4	2019	The solubility trend was determined to be, from most soluble to least soluble, X- = CH3CO2- > NO3- ~ BF4- > ClO4- > MnO4-.	perchlorate	114-118	NBL1, DAN family BMP antagonist	Homo sapiens	97-100
31082209-6	2019	For instance, the kinetics of NO3- to MnO4- exchange was much slower than expected based on that seen for NO3- to ClO4-.	perchlorate	114-118	NBL1, DAN family BMP antagonist	Homo sapiens	30-33
31082209-6	2019	For instance, the kinetics of NO3- to MnO4- exchange was much slower than expected based on that seen for NO3- to ClO4-.	perchlorate	114-118	NBL1, DAN family BMP antagonist	Homo sapiens	106-109
30822097-0	2019	Evidence for Biotic Perchlorate Reduction in Naturally Perchlorate-Rich Sediments of Pilot Valley Basin, Utah.	perchlorate	20-31	early growth response 3	Homo sapiens	85-90
30991129-15	2019	In addition, because of the increase in the expression of fas and c-fos protein in testicle tissues, perchlorate could induce apoptosis in spermatogenesis.	perchlorate	101-112	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	66-71
30822097-0	2019	Evidence for Biotic Perchlorate Reduction in Naturally Perchlorate-Rich Sediments of Pilot Valley Basin, Utah.	perchlorate	55-66	early growth response 3	Homo sapiens	85-90
30822097-3	2019	The arid Pilot Valley paleolake basin in Utah is a Mars analog environment whose sediments are naturally enriched with up to ~6.5 mug kg-1 perchlorate oxyanions.	perchlorate	139-150	early growth response 3	Homo sapiens	9-14
30822097-5	2019	Biogeochemical data suggest ongoing perchlorate reduction; phylogenetic data indicate the presence of diverse microbial communities; and laboratory enrichments using Pilot Valley sediments show that resident microbes can reduce perchlorate.	perchlorate	228-239	early growth response 3	Homo sapiens	166-171
30822097-6	2019	This is the first article of the co-existence of perchlorate-reducing microbes in an environment where perchlorate occurs naturally, arguing for Pilot Valley"s utility as an analog for studying biogeochemical processes that may have occurred, and may yet still be occurring, in ancient martian lacustrine sediments.	perchlorate	49-60	early growth response 3	Homo sapiens	145-150
30822097-6	2019	This is the first article of the co-existence of perchlorate-reducing microbes in an environment where perchlorate occurs naturally, arguing for Pilot Valley"s utility as an analog for studying biogeochemical processes that may have occurred, and may yet still be occurring, in ancient martian lacustrine sediments.	perchlorate	103-114	early growth response 3	Homo sapiens	145-150
30092492-2	2019	Infrared spectroscopy for formamide (FA) solutions of Ca(ClO4)2 shows that both CN stretch (nuCN) and CO stretch (nuCO) bands of FA undergo upshifts in the presence of Ca2+.	perchlorate	57-61	carbonic anhydrase 2	Homo sapiens	168-171
30868366-0	2019	NMR assignments of human linker histone H1x N-terminal domain and globular domain in the presence and absence of perchlorate.	perchlorate	113-124	H1.10 linker histone	Homo sapiens	40-43
30312915-4	2019	As the temperature dropped from 27 +- 2  C to 6 +- 1  C, the 1/2K1/2v,R for perchlorate reduction decreased from 7.37 mg1/2 L-1/2 h-1 to 0.19 mg1/2 L-1/2 h-1.	perchlorate	76-87	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	118-157
31536048-0	2018	Challenges in the Search for Perchlorate and Other Hydrated Minerals With 2.1-mum Absorptions on Mars.	perchlorate	29-40	methionyl-tRNA synthetase 1	Homo sapiens	97-101
30121623-6	2019	Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter.	perchlorate	71-82	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	58-61
30121623-6	2019	Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter.	perchlorate	71-82	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	115-118
30121623-6	2019	Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter.	perchlorate	71-82	transforming growth factor, beta 1	Mus musculus	130-135
30121623-6	2019	Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter.	perchlorate	71-82	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	115-118
30121623-6	2019	Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter.	perchlorate	71-82	transforming growth factor, beta 1	Mus musculus	288-293
30451256-3	2018	Isostructural 1(BF4)2 and 1(ClO4)2 show an abrupt and reversible spin transition with a much lower T1/2 for the BF4- salt.	perchlorate	28-32	spindlin 1	Homo sapiens	65-69
31458252-4	2018	The thermodynamically driven anion selectivity for exchange from the liquid phase into the coPIL films was determined to follow the order ClO4 - < PF6 - < FSI-.	perchlorate	138-142	sperm associated antigen 17	Homo sapiens	150-153
31458252-6	2018	The rate of ion transport through the p[N1-dMIm][PF6][ClO4] coPIL films, quantified by electrochemical impedance spectroscopy, linearly depends on the binary anion mole fraction of ClO4 - in solution (x ClO4 - ), enabling continuous tunability by over three orders of magnitude for ion conductivity in the coPIL films.	perchlorate	54-58	sperm associated antigen 17	Homo sapiens	49-52
31458252-6	2018	The rate of ion transport through the p[N1-dMIm][PF6][ClO4] coPIL films, quantified by electrochemical impedance spectroscopy, linearly depends on the binary anion mole fraction of ClO4 - in solution (x ClO4 - ), enabling continuous tunability by over three orders of magnitude for ion conductivity in the coPIL films.	perchlorate	181-185	sperm associated antigen 17	Homo sapiens	49-52
29874109-4	2018	Relative permeabilities ( PA/ PCl) calculated from reversal potentials measured in intact cells under bi-ionic conditions were as follows: SCN- >> ClO4- > [Formula: see text] > I- > Br- > Cl- >> gluconate.	perchlorate	153-157	polycystic kidney disease 2-like 1	Mus musculus	30-33
30277764-2	2018	By exploiting X-ray and ultraviolet photoelectron spectroscopy combined with an electrochemical cell (EC-XPS/UPS), we can electrochemically control the Fc SAMs and spectroscopically probe the induced changes with the ferrocene/ferrocenium (Fc/Fc+) redox center (Fe oxidation state), formation of 1:1 Fc+-ClO4- ion pairs, molecular orientation, and monolayer thickness.	perchlorate	304-308	methionine adenosyltransferase 1A	Homo sapiens	155-159
30277764-6	2018	The oxidation to Fc+ is also met with an increase in work function ascribed to the induced negative interfacial dipole caused by the presence of Fc+-ClO4- ion pairs along with a contribution from the reorientation of the Fc+ SAMs.	perchlorate	149-153	methionine adenosyltransferase 1A	Homo sapiens	225-229
29874109-5	2018	Relative conductances ( GA/ GCl) followed a similar trend of SCN- >> ClO4- > [Formula: see text] > I- > Br-  Cl- >> gluconate.	perchlorate	75-79	germ cell-less, spermatogenesis associated 1	Mus musculus	28-31
30112538-0	2018	Unexpected behaviour in derivatives of Barluenga"s reagent, Hal(Coll)2X (Coll = 2,4,6-trimethyl pyridine, collidine; Hal = I, Br; X = PF6, ClO4 & BF4).	perchlorate	139-143	histidine ammonia-lyase	Homo sapiens	60-63
29962071-1	2018	Heteropolynuclear complexes [(CNC)(PPh3 )PtM(PPh3 )]ClO4 [M=Au (1), Ag (2)] and [{Pt(CNC)(PPh3 )}2 M]ClO4 [M=Ag (3), Au (4); CNC=2,6-diphenylpyridinate] were prepared and studied by X-ray crystallography, spectroscopic techniques, and DFT calculations.	perchlorate	52-56	protein phosphatase 4 catalytic subunit	Homo sapiens	35-39
29962071-1	2018	Heteropolynuclear complexes [(CNC)(PPh3 )PtM(PPh3 )]ClO4 [M=Au (1), Ag (2)] and [{Pt(CNC)(PPh3 )}2 M]ClO4 [M=Ag (3), Au (4); CNC=2,6-diphenylpyridinate] were prepared and studied by X-ray crystallography, spectroscopic techniques, and DFT calculations.	perchlorate	52-56	protein phosphatase 4 catalytic subunit	Homo sapiens	45-49
29962071-1	2018	Heteropolynuclear complexes [(CNC)(PPh3 )PtM(PPh3 )]ClO4 [M=Au (1), Ag (2)] and [{Pt(CNC)(PPh3 )}2 M]ClO4 [M=Ag (3), Au (4); CNC=2,6-diphenylpyridinate] were prepared and studied by X-ray crystallography, spectroscopic techniques, and DFT calculations.	perchlorate	52-56	protein phosphatase 4 catalytic subunit	Homo sapiens	45-49
29691615-4	2018	In the terms of possible source, the perchlorate levels in the outdoor dust exhibited strong correlation with SO42- (r2 = 0.458**) and NO3- (r2 = 0.389**), indicating part of perchlorate in outdoor environment was likely from atmospheric oxidative process in summer.	perchlorate	37-48	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
29957358-1	2018	This paper evaluates the effect of various lyotropic anions (chloride, sulfate, perchlorate, iodide, nitrate, bromide) on the thermodynamic stability and dynamics of native cytochrome c (Cyt c) at pH 7.0.	perchlorate	80-91	cytochrome c, somatic	Equus caballus	173-185
29957358-1	2018	This paper evaluates the effect of various lyotropic anions (chloride, sulfate, perchlorate, iodide, nitrate, bromide) on the thermodynamic stability and dynamics of native cytochrome c (Cyt c) at pH 7.0.	perchlorate	80-91	cytochrome c, somatic	Equus caballus	187-192
29473274-4	2018	Moreover, at the specific concentration (for example, 10 mm), the variation of rectification ratio on the type of anions is ranged by Hofmeister series (Cl- >=NO3- >BF4- >ClO4- >PF6- >Tf2 N- ).	perchlorate	180-184	sperm associated antigen 17	Homo sapiens	190-193
30074036-4	2018	Various common anions, such as ClO4-, Cl-, or NO3- in the form of Al3+ salts [e.g. Al(ClO4)3, AlCl3 or Al(NO3)3], had no influence on the fluorescence behaviour of the sensors.	perchlorate	31-35	NBL1, DAN family BMP antagonist	Homo sapiens	106-109
29554623-6	2018	As a result of this presence, and the use of Chile saltpeter as a nitrogen fertilizer, perchlorate in Chile has been found at concentrations as high as 1480 microg L-1 in drinking water, 140 microg/kg-1 in fruits, and 30 microg L-1 in wine.	perchlorate	87-98	immunoglobulin kappa variable 1-16	Homo sapiens	164-167
29554623-6	2018	As a result of this presence, and the use of Chile saltpeter as a nitrogen fertilizer, perchlorate in Chile has been found at concentrations as high as 1480 microg L-1 in drinking water, 140 microg/kg-1 in fruits, and 30 microg L-1 in wine.	perchlorate	87-98	immunoglobulin kappa variable 1-16	Homo sapiens	228-231
29770145-7	2018	Compounds with (ClO4-) and (NO3-) were found to have the most efficient binding towards HSA as compared to BF4-and PF6-.	perchlorate	16-20	sperm associated antigen 17	Homo sapiens	115-118
29164882-6	2017	The results indicate that compounds 1 and 2 function as effective anion-selective transporters in the order of ClO4- > I- > NO3- > Br- > Cl- > SO42- > H2PO4- and exhibit anionophoric activity via a process of major anion exchange and minor anion/cation symport.	perchlorate	111-115	NBL1, DAN family BMP antagonist	Homo sapiens	130-133
29451800-2	2018	Its application in the synthesis of various isoquinolines and related polyaromatics in high atom economy at ambient temperature by applying a photosensitizer, Acr+-Mes ClO4-, and a new cobalt catalyst, Co(dmgH)2(4-CONMe2Py)Cl is reported.	perchlorate	168-172	acrosin	Homo sapiens	159-162
29308884-7	2018	Cyclic voltammetry of PdL in perchlorate-, chloride-, and sulfate-containing electrolytes revealed two-electron oxidation of the palladium center.	perchlorate	29-40	programmed cell death 1	Homo sapiens	22-25
29302666-3	2018	Reactions of L3aH2 and L3bH2 with CuX2 (X- = ClO4, Cl, NO3) yield a trinuclear complex (1) and 1-D copper chains (2, 3).	perchlorate	45-49	cut like homeobox 2	Homo sapiens	34-38
29139221-9	2018	Furthermore, perchlorate exposure reduced liver Dio1 mRNA expression and increased the content of pro-inflammatory cytokines in the thyroid and the serum.	perchlorate	13-24	iodothyronine deiodinase 1	Rattus norvegicus	48-52
28538093-8	2017	Although boron-doped diamond anodes mineralized haloacetic acids after formation, high production rates of chlorate and perchlorate (up to ~4 and 25 muM) made them inferior to TiO2/IrO2 anodes in terms of toxic byproduct formation.	perchlorate	120-131	latexin	Homo sapiens	149-152
29025080-7	2017	Higher levels of urinary perchlorate were associated with elevated levels of fasting glucose, HbA1c, insulin and homeostatic model assessment of insulin resistance (all Ptrend < 0.001).	perchlorate	25-36	insulin	Homo sapiens	101-108
29025080-7	2017	Higher levels of urinary perchlorate were associated with elevated levels of fasting glucose, HbA1c, insulin and homeostatic model assessment of insulin resistance (all Ptrend < 0.001).	perchlorate	25-36	insulin	Homo sapiens	145-152
28387958-6	2017	The detection limits for the four anions chloride, nitrate, perchlorate, and formate could be lowered from 4, 4.3, 4.2, and 7.2 muM obtained without trapping respectively to 127, 142, 139, and 451 nM with trapping.	perchlorate	60-71	latexin	Homo sapiens	128-131
28341379-5	2017	Addition of many co-anions showed the competition adsorption towards perchlorate, especially in the presence of NO3-.	perchlorate	69-80	NBL1, DAN family BMP antagonist	Homo sapiens	112-115
28613850-3	2017	Herein, we report a Co(II)-based homogeneous catalyst, [Co(NTB)CH3CN](ClO4)2 (1, NTB = tris(benzimidazolyl-2-methyl)amine), which shows high selectivity and stability for the catalytic reduction of CO2 to CO in a water-containing system driven by visible light, with turnover number (TON) and turnover frequency (TOF) values of 1179 and 0.032 s-1, respectively, and selectivity to CO of 97%.	perchlorate	70-75	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	20-25
28198582-4	2017	Counterintuitively, we find that conductance of this perfectly cation-selective channel increases about two-fold in the H2 PO4- <Cl-  Br-  NO3- <ClO4- <SCN- series.	perchlorate	151-155	NBL1, DAN family BMP antagonist	Homo sapiens	142-145
28382345-0	2017	Anion exchange dynamics in the capture of perchlorate by a cationic Ag-based MOF.	perchlorate	42-53	lysine acetyltransferase 8	Homo sapiens	77-80
28440376-2	2017	The perchlorate concentrations in the groundwater, farmland soil, lettuce, and rhizosphere soil samples ranged from below detection limit to 60.2 mug L-1, from below detection limit to 249 mug kg-1 dry weight (dw), from 2.07 to 1010 mug kg-1 wet weight, and from below detection limit to 314 mug kg-1 dw, respectively.	perchlorate	4-15	immunoglobulin kappa variable 1-16	Homo sapiens	150-153
28188514-2	2017	The chemosensor (E)-2-(4-mercaptostyryl)quinolin-8-ol L showed high selectivity for detection of cyanide over other anions such as F , Cl , Br , I , NO3 , SCN , N3 , ClO4 , H2PO4 , AcO , HCO3 , SO42  and HSO4 in aqueous solution.	perchlorate	166-170	NBL1, DAN family BMP antagonist	Homo sapiens	149-152
28188514-2	2017	The chemosensor (E)-2-(4-mercaptostyryl)quinolin-8-ol L showed high selectivity for detection of cyanide over other anions such as F , Cl , Br , I , NO3 , SCN , N3 , ClO4 , H2PO4 , AcO , HCO3 , SO42  and HSO4 in aqueous solution.	perchlorate	166-170	sorcin	Homo sapiens	155-158
27958678-1	2017	A dinuclear cobalt complex [Co2 (OH)L1 ](ClO4 )3 (1, L1 =N[(CH2 )2 NHCH2 (m-C6 H4 )CH2 NH(CH2 )2 ]3 N) displays high selectivity and efficiency for the photocatalytic reduction of CO2 to CO in CH3 CN/H2 O (v/v=4:1) under a 450 nm LED light irradiation, with a light intensity of 100 mW cm-2 .	perchlorate	41-45	complement C2	Homo sapiens	28-38
27990520-1	2017	In this paper we present the characterization of a complex with the formula [Mn2Ca2(hmp)6(H2O)4(CH3CN)2](ClO4)4 (1), where hmp-H = 2-(hydroxymethyl)pyridine.	perchlorate	105-109	inner membrane mitochondrial protein	Homo sapiens	84-87
27990520-1	2017	In this paper we present the characterization of a complex with the formula [Mn2Ca2(hmp)6(H2O)4(CH3CN)2](ClO4)4 (1), where hmp-H = 2-(hydroxymethyl)pyridine.	perchlorate	105-109	inner membrane mitochondrial protein	Homo sapiens	123-126
27916129-7	2017	At optimized EME conditions (polypropylene hollow fiber impregnated with NB + 3% (w/w) BU6, extraction voltage 25 V, extraction time 15 min, deionized water as acceptor solution) perchlorate was selectively extracted from tap water at concentrations below the guideline value recommended by United States Environmental Protection Agency.	perchlorate	179-190	nuclear RNA export factor 1	Homo sapiens	222-225
25108511-8	2014	Significant down-regulation of thyroid hormone receptor alpha (THR-alpha) and beta (THR-beta) transcripts and up-regulation of deiodinase 2 (DIO2) transcripts were observed in the fish exposed to perchlorate.	perchlorate	196-207	type II iodothyronine deiodinase	Oryzias latipes	141-145
27786456-5	2016	Complexation of the N,N"-di(4-pyridyl)-1,4,5,8-naphthalenediimide (DPNDI) ligand and CdX2 (X = NO3- or ClO4-) produces complexes MOFs 1 and 2 with a one-dimensional (1D) nonporous network and a porous, noninterpenetrated two-dimensional (2D) square-grid structure, respectively.	perchlorate	103-107	caudal type homeobox 2	Homo sapiens	85-89
27454810-2	2016	In several cases, even the neutral ligands, in addition to their protonated HL(+) and H2L(2+) (L = L1 and L2) forms, bind anions such as F(-), NO3(-), PF6(-), ClO4(-), and SO4(2-) to form stable complexes in water.	perchlorate	159-163	L1 cell adhesion molecule	Homo sapiens	99-108
27454810-2	2016	In several cases, even the neutral ligands, in addition to their protonated HL(+) and H2L(2+) (L = L1 and L2) forms, bind anions such as F(-), NO3(-), PF6(-), ClO4(-), and SO4(2-) to form stable complexes in water.	perchlorate	159-163	sperm associated antigen 17	Homo sapiens	151-154
26841777-10	2016	We propose that aerobic methane oxidation coupled to denitrification and perchlorate reduction (AMO-D and AMO-PR) directly oxidized methane and reduced NO3 (-) to NO2 (-) or N2O under anoxic condition, producing organic matter for methanol-assimilating denitrification and perchlorate reduction (MA-D and MA-PR) to reduce NO3 (-).	perchlorate	73-84	NBL1, DAN family BMP antagonist	Homo sapiens	152-155
26841777-10	2016	We propose that aerobic methane oxidation coupled to denitrification and perchlorate reduction (AMO-D and AMO-PR) directly oxidized methane and reduced NO3 (-) to NO2 (-) or N2O under anoxic condition, producing organic matter for methanol-assimilating denitrification and perchlorate reduction (MA-D and MA-PR) to reduce NO3 (-).	perchlorate	73-84	NBL1, DAN family BMP antagonist	Homo sapiens	322-325
26841777-10	2016	We propose that aerobic methane oxidation coupled to denitrification and perchlorate reduction (AMO-D and AMO-PR) directly oxidized methane and reduced NO3 (-) to NO2 (-) or N2O under anoxic condition, producing organic matter for methanol-assimilating denitrification and perchlorate reduction (MA-D and MA-PR) to reduce NO3 (-).	perchlorate	273-284	NBL1, DAN family BMP antagonist	Homo sapiens	152-155
26841777-11	2016	Simultaneously, bacteria capable of anaerobic methane oxidation coupled to denitrification and perchlorate reduction (ANMO-D and ANMO-PR) used methane as the electron donor to respire NO3 (-) or ClO4 (-) directly.	perchlorate	95-106	NBL1, DAN family BMP antagonist	Homo sapiens	184-187
26754589-0	2016	Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice.	perchlorate	18-29	metallothionein 1	Mus musculus	168-185
26586233-4	2015	The PXRD study shows the bulk purity of both the complexes and TGA analysis of 2 exhibits that the structure is thermally stable up to 250  C. Complex 1 shows a nice anion exchange property with replacement of weakly coordinated perchlorate with the inclusion of new anions; and the anion exchanged solids were characterised by FT-IR, PXRD and photoluminescence properties.	perchlorate	229-240	T-box transcription factor 1	Homo sapiens	63-66
26440557-1	2015	Efficient aggregation induced phosphorescence emission (AIPE) of an ionic Ir(iii) complex occurs when the counterion (PF6(-)) is exchanged specifically by ClO4(-) in aqueous media.	perchlorate	155-159	sperm associated antigen 17	Homo sapiens	118-121
26435266-1	2015	A poly(3,4-ethylenedioxythiophene)-b-poly(ethylene glycol) (PEDOT-b-PEG) block copolymer doped with perchlorate on FTO shows excellent optical and interfacial performance as a counter electrode (CE), such as low charge transfer resistance and low reflectivity for polymer electrolyte-based solid-state dye-sensitized solar cells (DSCs), resulting in 8.45% energy conversion efficiency, greater than the common Pt CE, via a facile room-temperature process.	perchlorate	100-111	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	115-118
25896817-10	2015	Specificity of tumoural iodine uptake was assessed by blocking hNIS in vivo with perchlorate.	perchlorate	81-92	solute carrier family 5 member 5	Homo sapiens	63-67
25896817-12	2015	Iodine uptake was highly specific in teratomas, as in vivo blocking of hNIS with perchlorate led to uptake rates comparable to tracer uptake in non-transgene tumours.	perchlorate	81-92	solute carrier family 5 member 5	Homo sapiens	71-75
25730599-7	2015	A log-log plot of the normalized SERS intensity against perchlorate concentration showed a good linear relationship.	perchlorate	56-67	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	33-37
25700155-1	2015	The self-assembly between a water-soluble bis-bidentate ligand L(18w) and Co(II) salts in water affords three high-spin Co(II) products: a dinuclear meso-helicate [Co2(L(18w))3]X4; a tetrahedral cage [Co4(L(18w))6]X8; and a dodecanuclear truncated-tetrahedral cage [Co12(L(18w))18]X24 (X = BF4 or ClO4).	perchlorate	297-301	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	74-80
25610949-3	2015	The molecules are compared with previously known mu-hydroxo complexes with other counterions, such as I3(-), BF4(-), and ClO4(-), which demonstrates that the nature of the counterion can affect the spin-state ordering dramatically.	perchlorate	121-125	spindlin 1	Homo sapiens	198-202
25469496-2	2015	Ligands bpylC CH and metalloligands bpylC CAuL (L=PPh3 , PMePh2 , PCy3 , CNXy) react with MX2 (M=Fe, Zn, X=ClO4 ; M=Co, X=BF4 ) to give complexes [M(bpylC CZ)3 ]X2 (Z=H or AuL).	perchlorate	107-111	MX dynamin like GTPase 2	Homo sapiens	90-93
25514572-0	2014	Negative association between serum parathyroid hormone levels and urinary perchlorate, nitrate, and thiocyanate concentrations in U.S. adults: the National Health and Nutrition Examination Survey 2005-2006.	perchlorate	74-85	parathyroid hormone	Homo sapiens	35-54
25514572-2	2014	This exploratory study investigated the association among urinary perchlorate, nitrate, and thiocyanate concentrations and parathyroid hormone (PTH) levels in the general U.S. population.	perchlorate	66-77	parathyroid hormone	Homo sapiens	123-142
25266857-1	2014	The aggregates of perylenediimide based chemosensor (PDI 1) undergo de-aggregation induced fluorescence quenching selectively with ClO4(-) ions both in the solution and in the solid phase and can detect ClO4(-) ions in drinking water and fireworks.	perchlorate	131-135	peptidyl arginine deiminase 1	Homo sapiens	53-58
25266857-1	2014	The aggregates of perylenediimide based chemosensor (PDI 1) undergo de-aggregation induced fluorescence quenching selectively with ClO4(-) ions both in the solution and in the solid phase and can detect ClO4(-) ions in drinking water and fireworks.	perchlorate	203-207	peptidyl arginine deiminase 1	Homo sapiens	53-58
25211163-4	2014	Compounds and are prepared following a metal-templated synthesis, while compounds and are prepared by direct synthesis, which includes using a pre-isolated macrocycle, [H4L(Me-pn)](ClO4)2/[H4L(Et-pn)](ClO4)2, as a reactant.	perchlorate	181-185	H4 clustered histone 7	Homo sapiens	169-172
24835940-2	2014	The study of temperature dependence of the band position and full width at half maximum allowed us to link each of the observed phase transitions (at: TC1(h) 355K, TC2(h) 341K and TC3(h) 315K) with the changes either of the crystal structure or with the reorientational motions of the dimethylosulphoxide (DMSO) ligands and/or [Zn(OS(CH3)2)6](2+) and/or the ClO4(-) anions and/or with all these changes together.	perchlorate	358-362	transcobalamin 1	Homo sapiens	151-154
27643659-7	2016	These findings implied that ratio of NO3- to ClO4- loadings and acetate loading were two key factors impacting ClO4- reduction and microbial structure along the filter.	perchlorate	111-115	NBL1, DAN family BMP antagonist	Homo sapiens	37-40
26869048-0	2016	Perchlorate levels found in tap water collected from several cities in Turkey.	perchlorate	0-11	nuclear RNA export factor 1	Homo sapiens	28-31
26869048-4	2016	The aim of this study was to determine the perchlorate levels in tap water from five cities in Turkey.	perchlorate	43-54	nuclear RNA export factor 1	Homo sapiens	65-68
26869048-5	2016	Perchlorate concentrations of 145 tap water samples collected from Ankara, Isparta, Istanbul, Kayseri, and Sakarya were determined by liquid chromatography-tandem mass spectrometry.	perchlorate	0-11	nuclear RNA export factor 1	Homo sapiens	34-37
26422179-5	2015	Rapid ReV(hoz)2 oxidation is mainly promoted by highly reactive ClOx- formed from the reduction of ClO4-.	perchlorate	99-103	cut like homeobox 1	Homo sapiens	64-68
27358736-5	2015	Finally, this approach has been extended to the chemical alloy [Fe(Htrz)2.95(NH2trz)0.05](ClO4)2 in order to prepare NPs exhibiting a cooperative and hysteretic spin transition centred closer to room temperature.	perchlorate	90-94	spindlin 1	Homo sapiens	161-165
26076066-2	2015	The structurally characterized dimercapto-bridged Mn(II) dimer [Mn(II)2(LS)(LSH)]ClO4 (Mn(II)2SH) is formed by reaction of the LS ligand (2,2"-(2,2"-bipyridine-6,6"-diyl)bis(1,1-diphenylethanethiolate)) with Mn(II).	perchlorate	81-85	helicase, lymphoid specific	Homo sapiens	76-79
24934974-0	2014	Detection of perchlorate using Ag/DMAH(+) SERS-active capture matrices.	perchlorate	13-24	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	42-46
24934974-1	2014	In this communication, the fabrication of SERS-active capture matrices for the detection of perchlorate is described.	perchlorate	92-103	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	42-46
25322447-13	2014	The 2-naphtholate analogue of this intermediate, [Fe(TPA)(2-naphtholate)(OCH3)]ClO4 (6), was characterized by single-crystal X-ray diffraction (C29H28FeN4O2,ClO4; P21; a = 13.2646(2) A, b = 15.2234(3) A, c = 13.7942(3) A; Z = 4).	perchlorate	79-83	plasminogen activator, tissue type	Homo sapiens	53-56
25322447-13	2014	The 2-naphtholate analogue of this intermediate, [Fe(TPA)(2-naphtholate)(OCH3)]ClO4 (6), was characterized by single-crystal X-ray diffraction (C29H28FeN4O2,ClO4; P21; a = 13.2646(2) A, b = 15.2234(3) A, c = 13.7942(3) A; Z = 4).	perchlorate	157-161	plasminogen activator, tissue type	Homo sapiens	53-56
24149973-10	2014	TPO antibodies were significant predictors of free T4 among non-pregnant women only when the models included urinary perchlorate, nitrate, or thiocyanate.	perchlorate	117-128	thyroid peroxidase	Homo sapiens	0-3
24565279-13	2014	The Hofmeister series in the single-electrode capacitance was PF6(-)>BF4(-)>ClO4(-)>BrO4(-)>IO4(-) .	perchlorate	82-86	sperm associated antigen 17	Homo sapiens	62-65
24787025-9	2014	The presence of two tert-butyl groups on the aminophenolate ring in 7 ClO4 makes the complex slow to cleave the C-C bond of 4,6-di-(t)Bu-HAP, whereas 4 BPh4 containing 4-Me-HAP displays fastest reactivity.	perchlorate	70-74	reticulon 3	Homo sapiens	137-140
24981551-5	2014	According to small-angle X-ray scattering measurements, approximately 25% of the cyt c molecules were dimerized in the molten globule state containing 125 mM ClO4(-).	perchlorate	158-162	cytochrome c, somatic	Homo sapiens	81-86
24787025-9	2014	The presence of two tert-butyl groups on the aminophenolate ring in 7 ClO4 makes the complex slow to cleave the C-C bond of 4,6-di-(t)Bu-HAP, whereas 4 BPh4 containing 4-Me-HAP displays fastest reactivity.	perchlorate	70-74	reticulon 3	Homo sapiens	173-176
24521418-4	2014	The results indicate that NOM strongly inhibits perchlorate removal by both ARP, because it competes with sulfite for UV light.	perchlorate	48-59	mesencephalic astrocyte derived neurotrophic factor	Homo sapiens	76-79
24441029-1	2014	Three ion-pair complexes based on spin-crossover [Mn(5-Br-sal-N-1,5,8,12)]ClO4 with TBA2[Ni(mnt)2], TBA2[Pt(mnt)2] (mnt = maleonitriledithiolate) and TBA[Ni(dmit)2] respectively (dmit = 2-thioxo-1,3-dithiole-4,5-dithiolato) have been synthesized and structurally characterized.	perchlorate	74-78	spindlin 1	Homo sapiens	34-38
24403126-3	2014	Treatment of 2 with [Au2 (dppe)2 ](2+) (dppe=1,2-bis(diphenylphosphino)ethane) leads to the formation of [Au4 Co2 (dppe)2 (D-nmp)4 ](2+) (3(2+) ), which consists of an 18-membered Au(I) 4 Co(III) 2 metallaring that accommodates a tetrahedral anion (BF4 (-) , ClO4 (-) , ReO4 (-) ).	perchlorate	259-263	complement C2	Homo sapiens	110-113
24513648-1	2014	The reaction between a potential flexidentate pyridyl-azo-oxime HL1 and Co(ClO4)2 yields novel homoleptic complexes of types [Co(III)(L(-I))3], 2 and [Co(III)(L(-I))2]ClO4, 3+ClO4 in N6 and N4O2 coordination environments respectively.	perchlorate	75-79	intelectin 1	Homo sapiens	64-67
24513648-1	2014	The reaction between a potential flexidentate pyridyl-azo-oxime HL1 and Co(ClO4)2 yields novel homoleptic complexes of types [Co(III)(L(-I))3], 2 and [Co(III)(L(-I))2]ClO4, 3+ClO4 in N6 and N4O2 coordination environments respectively.	perchlorate	167-171	intelectin 1	Homo sapiens	64-67
25079409-1	2014	Cross-linked Fe(III)-chitosan composite (Fe-CB) was used as the adsorbent for removing perchlorate from the aqueous solution.	perchlorate	87-98	FECB	Homo sapiens	41-46
25079409-5	2014	The perchlorate uptake onto Fe-CB obeyed Langmuir isotherm model.	perchlorate	4-15	FECB	Homo sapiens	28-33
24236758-7	2013	The impact of the orientation of the perchlorate counterions is disclosed by comparison to J(AB) studies using structurally similar ligands but with different electronegativity (namely, BF4(-), BCl4(-), and BBr4(-)).	perchlorate	37-48	BCL3 transcription coactivator	Homo sapiens	194-198
24228842-1	2013	We report the synthesis and structural characterization of a dicobalt(III) complex with a mu-OH,mu-O2 core, namely mu-OH,mu-O2-[Co(enN4)]2(X)3 [1(ClO4)3 and 1(BF4)3].	perchlorate	146-151	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	70-73
24056247-3	2013	In this study, batch kinetic experiments were conducted to characterize the kinetics of perchlorate destruction by the sulfite/UV-L ARP.	perchlorate	88-99	mesencephalic astrocyte derived neurotrophic factor	Homo sapiens	132-135
24056247-7	2013	The ultimate product of perchlorate degradation by the sulfite/UV-L ARP is chloride, but chlorate was detected as an intermediate.	perchlorate	24-35	mesencephalic astrocyte derived neurotrophic factor	Homo sapiens	68-71
23578330-8	2013	Single crystal X-ray diffraction determined for [Cu(H2L1)](ClO4)2 showed the copper center in a distorted octahedral environment bound to the N4O donors of the macrobicycle and one oxygen atom from a carboxylic arm, while for [CuL2] it showed the copper center in a trigonal bipyramid geometry only bound to the donors of the macrobicycle and leaving the carboxylate arms away from the coordination sphere.	perchlorate	59-64	cullin 2	Homo sapiens	227-231
23989602-1	2013	Self-assembly of CuX2 (X(-) = ClO4(-) and BF4(-)) with 2,3-bis(nicotinoyloxy)naphthalene yields a 1D loop-chain skeleton.	perchlorate	30-34	cut like homeobox 2	Homo sapiens	17-21
23801373-1	2013	Investigations into the anion effects on the molecular construction of a series of CuX2 (X- = BF4-, ClO4-, and NO3-) complexes with 1,3,5-tris(isonicotinoyloxyethyl)cyanurate (L) were carried out.	perchlorate	100-104	cut like homeobox 2	Homo sapiens	83-87
23455760-1	2013	UNLABELLED: Congenital hypothyroidism (CH) due to thyroglobulin (TG) deficit is an autosomal recessive disease (OMIM #274700) characterized by hypothyroidism, goiter, low serum TG, and a negative perchlorate discharge test.	perchlorate	196-207	thyroglobulin	Homo sapiens	50-63
23455760-1	2013	UNLABELLED: Congenital hypothyroidism (CH) due to thyroglobulin (TG) deficit is an autosomal recessive disease (OMIM #274700) characterized by hypothyroidism, goiter, low serum TG, and a negative perchlorate discharge test.	perchlorate	196-207	thyroglobulin	Homo sapiens	65-67
23629634-4	2013	The exchange of PF6(-) ion with ClO4(-) ion resulted in the intake of aromatic guest molecules, which were monitored by IR and UV-Vis spectroscopy.	perchlorate	32-36	sperm associated antigen 17	Homo sapiens	16-19
23807022-0	2013	Contribution of tap water to chlorate and perchlorate intake: a market basket study.	perchlorate	42-53	nuclear RNA export factor 1	Homo sapiens	16-19
23721373-5	2013	While perchlorate-reducing bacteria (PRB), assayed by qPCR targeting the pcrA gene, remained stable throughout, sulfate-reducing bacteria (SRB), assayed by the dsrA gene, increased almost 3 orders of magnitude when significant SO4(2-) reduction occurred in stage 2.	perchlorate	6-17	RB transcriptional corepressor 1	Homo sapiens	37-40
23695836-5	2013	With acetate as the electron donor, strain CAB completely reduced perchlorate (ClO4(-)) or chlorate (ClO3(-)) [collectively designated (per)chlorate] to innocuous chloride (Cl(-)), likely using the perchlorate reductase (Pcr) and chlorite dismutase (Cld) enzymes.	perchlorate	66-77	neural proliferation, differentiation and control 1	Homo sapiens	43-46
23695836-5	2013	With acetate as the electron donor, strain CAB completely reduced perchlorate (ClO4(-)) or chlorate (ClO3(-)) [collectively designated (per)chlorate] to innocuous chloride (Cl(-)), likely using the perchlorate reductase (Pcr) and chlorite dismutase (Cld) enzymes.	perchlorate	79-83	neural proliferation, differentiation and control 1	Homo sapiens	43-46
22692585-1	2012	The catalytic durability of an organic photocatalyst, 9-mesityl-10-methyl acridinium ion (Acr(+)-Mes), has been dramatically improved by the addition of [{tris(2-pyridylmethyl)amine}Cu(II)](ClO(4))(2) ([(tmpa)Cu(II)](2+)) in the photocatalytic oxygenation of p-xylene by molecular oxygen in acetonitrile.	perchlorate	190-198	acrosin	Homo sapiens	90-93
23409803-1	2013	ClO(4)(-)MgAl-LDH3, a MgAl (Mg/Al = 3) layered double hydroxide (LDH) containing perchlorate, swells and forms colloidal suspensions (sols) via the gel state in concentrated aqueous solutions of zwitterionic compounds related to amino acids.	perchlorate	81-92	lactate dehydrogenase C	Homo sapiens	14-18
23409803-1	2013	ClO(4)(-)MgAl-LDH3, a MgAl (Mg/Al = 3) layered double hydroxide (LDH) containing perchlorate, swells and forms colloidal suspensions (sols) via the gel state in concentrated aqueous solutions of zwitterionic compounds related to amino acids.	perchlorate	81-92	lactate dehydrogenase C	Homo sapiens	14-17
23426615-9	2013	TSH receptor gene mutations were found in 8.7% of patients with persistent thyroid dysfunction and negative perchlorate discharge test.	perchlorate	108-119	thyroid stimulating hormone receptor	Homo sapiens	0-12
23188482-2	2013	Food and tap water are likely sources of environmental exposure to perchlorate.	perchlorate	67-78	nuclear RNA export factor 1	Homo sapiens	9-12
23188482-5	2013	Separate models of NHANES 2005-2006 data (n=2841) evaluated the association between urinary perchlorate and perchlorate consumed via residential tap water.	perchlorate	108-119	nuclear RNA export factor 1	Homo sapiens	145-148
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	30-41	nuclear RNA export factor 1	Homo sapiens	60-63
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	30-41	nuclear RNA export factor 1	Homo sapiens	172-175
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	113-124	nuclear RNA export factor 1	Homo sapiens	60-63
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	113-124	nuclear RNA export factor 1	Homo sapiens	172-175
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	113-124	nuclear RNA export factor 1	Homo sapiens	60-63
23188482-11	2013	In a separate model, however, perchlorate consumed via home tap water contributed significantly to adult urinary perchlorate: 2.11E-4 ng ClO(4)(-)/ml per ng perchlorate in tap water consumed.	perchlorate	113-124	nuclear RNA export factor 1	Homo sapiens	172-175
23188482-12	2013	In a nationally representative sample of the United States 6-84 YO, diet and tap water contributed significantly to urinary perchlorate, with diet contributing substantially more than tap water.	perchlorate	124-135	nuclear RNA export factor 1	Homo sapiens	77-80
23006481-6	2012	Perchlorate, a competitive inhibitor of NIS, prevented these effects, indicating that an increase in intracellular I(-) regulates NIS.	perchlorate	0-11	solute carrier family 5 member 5	Rattus norvegicus	40-43
23006481-6	2012	Perchlorate, a competitive inhibitor of NIS, prevented these effects, indicating that an increase in intracellular I(-) regulates NIS.	perchlorate	0-11	solute carrier family 5 member 5	Rattus norvegicus	130-133
20882593-9	2012	In addition, the significant decreased gene expression of Thyroglobulin (Tg) and thyroperoxidase (TPO) were both observed at the treatment of high dose perchlorate.	perchlorate	152-163	thyroglobulin	Rattus norvegicus	58-71
20882593-9	2012	In addition, the significant decreased gene expression of Thyroglobulin (Tg) and thyroperoxidase (TPO) were both observed at the treatment of high dose perchlorate.	perchlorate	152-163	thyroglobulin	Rattus norvegicus	73-75
20882593-9	2012	In addition, the significant decreased gene expression of Thyroglobulin (Tg) and thyroperoxidase (TPO) were both observed at the treatment of high dose perchlorate.	perchlorate	152-163	thyroid peroxidase	Rattus norvegicus	81-96
20882593-9	2012	In addition, the significant decreased gene expression of Thyroglobulin (Tg) and thyroperoxidase (TPO) were both observed at the treatment of high dose perchlorate.	perchlorate	152-163	thyroid peroxidase	Rattus norvegicus	98-101
20882593-10	2012	These results suggested that perchlorate can suppress gene expression of Tg and TPO which directly involved in biosynthesis of thyroid hormones, and may therefore aggravate the perturbation of thyroid homeostasis in addition to competitive inhibition of iodide uptake.	perchlorate	29-40	thyroglobulin	Rattus norvegicus	73-75
20882593-10	2012	These results suggested that perchlorate can suppress gene expression of Tg and TPO which directly involved in biosynthesis of thyroid hormones, and may therefore aggravate the perturbation of thyroid homeostasis in addition to competitive inhibition of iodide uptake.	perchlorate	29-40	thyroid peroxidase	Rattus norvegicus	80-83
22549510-7	2012	However, Kcne2 deletion doubled the rate of free I(-) efflux from the thyroid following ClO(4)(-) injection, a NIS-independent process.	perchlorate	88-97	potassium voltage-gated channel subfamily E regulatory subunit 2	Homo sapiens	9-14
22365567-3	2012	US EPA currently puts perchlorate on the final third Contamination Candidate List (CCL3) and suggests a health reference level at 4.9 mug L-1.	perchlorate	22-33	C-C motif chemokine ligand 3	Homo sapiens	83-87
22365567-4	2012	The MRL of perchlorate was therefore set at 5.0 mug L-1 by the authors for method validation.	perchlorate	11-22	immunoglobulin kappa variable 1-16	Homo sapiens	52-55
22191376-5	2012	The model explicitly considers four mechanisms involved in how three important operating conditions (H(2) pressure, nitrate loading, and perchlorate loading) affect nitrate and perchlorate removals: (1) competition for H(2), (2) promotion of PRB growth due to having two electron acceptors (nitrate and perchlorate), (3) competition between nitrate and perchlorate reduction for the same resources in the PRB: electrons and possibly reductase enzymes, and (4) competition for space in the biofilm.	perchlorate	137-148	RB transcriptional corepressor 1	Homo sapiens	242-245
22301678-4	2012	The other type is pale pink-coloured Co(II) complexes, [Co(MeOH)(H(2)BPPA)](ClO(4)(-))(2) (2 (ClO(4)(-))(2)) and [Co(MeCN)(H(2)BPPA)](I(-))(2) (2 (I(-))(2)), which were obtained when X = I(-) and ClO(4)(-), respectively.	perchlorate	76-82	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	37-43
22041941-3	2011	The interactions of E-1 with the protonated amino acid perchlorates, ClO(4)(-) H(3)N(+)(CH(2))(n)COOH (n = 2, 5 and 10, A2, A5 and A10, respectively), were studied by optical methods, (1)H NMR and mass spectroscopy.	perchlorate	69-75	small nucleolar RNA, H/ACA box 73A	Homo sapiens	20-23
21328502-1	2011	A novel bispyrazolylpyridine ligand incorporating lateral phenol groups, H(4)L, has led to an Fe(II) spin-crossover (SCO) complex, [Fe(H(4)L)(2)][ClO(4)](2) H(2)O 2 (CH(3))(2)CO (1), with an intricate network of intermolecular interactions.	perchlorate	146-152	H4 clustered histone 7	Homo sapiens	73-78
21550633-0	2011	Pendrin mediates uptake of perchlorate in a mammalian in vitro system.	perchlorate	27-38	solute carrier family 26 member 4	Homo sapiens	0-7
21550633-3	2011	Because transport of iodide from the thyroid follicular cells to the follicular lumen is mediated by the protein pendrin at the apical surface, we hypothesized that perchlorate may also interact with this protein.	perchlorate	165-176	solute carrier family 26 member 4	Homo sapiens	113-120
21550633-8	2011	Thus, recombinant HeLa cells expressing pendrin protein accumulate iodide and perchlorate intracellularly, indicating that pendrin is involved in the uptake of perchlorate.	perchlorate	78-89	solute carrier family 26 member 4	Homo sapiens	40-47
21550633-8	2011	Thus, recombinant HeLa cells expressing pendrin protein accumulate iodide and perchlorate intracellularly, indicating that pendrin is involved in the uptake of perchlorate.	perchlorate	78-89	solute carrier family 26 member 4	Homo sapiens	123-130
21550633-8	2011	Thus, recombinant HeLa cells expressing pendrin protein accumulate iodide and perchlorate intracellularly, indicating that pendrin is involved in the uptake of perchlorate.	perchlorate	160-171	solute carrier family 26 member 4	Homo sapiens	40-47
21550633-8	2011	Thus, recombinant HeLa cells expressing pendrin protein accumulate iodide and perchlorate intracellularly, indicating that pendrin is involved in the uptake of perchlorate.	perchlorate	160-171	solute carrier family 26 member 4	Homo sapiens	123-130
21550633-9	2011	Additional results from this study suggest that iodide and perchlorate competitively inhibit each other for uptake by pendrin.	perchlorate	59-70	solute carrier family 26 member 4	Homo sapiens	118-125
21837715-3	2011	In the homoleptic analogue, [Ni(III)([9]aneS(3))(2)](ClO(4))(3), structurally characterized at 30 K, the Ni-S distances [2.249(6), 2.251(5) and 2.437(2) A] are consistent with a Jahn-Teller distorted octahedral stereochemistry.	perchlorate	53-60	solute carrier family 5 member 5	Homo sapiens	105-109
21738937-5	2011	Perchlorate concentrations in commercial milk were significantly higher in Japan than in Sri Lanka, while iodide and nitrate levels in milk between the two countries were comparable.	perchlorate	0-11	sorcin	Homo sapiens	89-92
20571527-0	2011	Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data.	perchlorate	11-22	nuclear RNA export factor 1	Homo sapiens	46-49
20571527-5	2011	By subtracting daily food doses of perchlorate from the oral reference dose (RfD), we derive an allowances for perchlorate in tap water for several populations.	perchlorate	111-122	nuclear RNA export factor 1	Homo sapiens	126-129
21090606-5	2010	The median perchlorate, nitrate, and iodide levels measured in tap water were 1.16, 758, and 4.55 mug/L, respectively.	perchlorate	11-22	nuclear RNA export factor 1	Homo sapiens	63-66
21358184-5	2011	The perchlorate discharge test can detect the underlying thyroid biochemical defect and is useful for the evaluation of goiter or for the clinical diagnosis of PDS in a patient with a non-diagnostic SLC26A4 genotype.	perchlorate	4-15	solute carrier family 26 member 4	Homo sapiens	199-206
21090606-10	2010	Using individual tap water consumption data and body weight, we estimated the median perchlorate, nitrate, and iodide dose attributable to tap water as 9.11, 11300, and 43.3 ng/kg-day, respectively, for U.S. adults.	perchlorate	85-96	nuclear RNA export factor 1	Homo sapiens	139-142
21090606-0	2010	Perchlorate, nitrate, and iodide intake through tap water.	perchlorate	0-11	nuclear RNA export factor 1	Homo sapiens	48-51
21090606-3	2010	This study investigates the intake of perchlorate, nitrate, and iodide attributable to direct and indirect tap water consumption.	perchlorate	38-49	nuclear RNA export factor 1	Homo sapiens	107-110
21090606-11	2010	This perchlorate exposure dose from tap water is relatively small compared to the total perchlorate exposure dose previously characterized for the U.S. adults (median 64 ng/kg-day) and the U.S. EPA reference dose (700 ng/kg-day).	perchlorate	5-16	nuclear RNA export factor 1	Homo sapiens	36-39
20520918-4	2010	Compound [Cu(Hpap)(ClO(4))(H(2)O)](x) was isolated in both dimeric (x = 2) and polymeric (x = n) state, representing an example of supramolecular isomerism.	perchlorate	19-26	acid phosphatase 5, tartrate resistant	Homo sapiens	13-17
20690733-2	2010	The molecular structure of the resultant nitrosyl complex, [Ru(L(PB1))(PPh(3))(2)(NO)Cl](ClO(4)) [2; L(PB1)H = 5-methyl-7-nitro-2-(4-nitrophenyl)benzoxazole] was determined, and a different sigma-arylruthenium cyclometallate was characterized in which the benzoxazole derivative was found to be coordinated to the metal center.	perchlorate	89-96	polybromo 1	Homo sapiens	103-106
20396815-7	2010	Temperature-dependent magnetic susceptibility measurements of the iron(II) complexes 28 and 29 have shown the 3 : 1-type complex [Fe(II)(L10)3](ClO4)2 H2O (28) to be in the low-spin state over the range 300-2 K and the 2 : 1-type complex 29 to be a spin crossover compound with T(1/2) = 269 K whereas the dicyanamido-bridged complex 30 remains in the high-spin state even down to 113 K, according to X-ray diffraction data.	perchlorate	143-149	ribosomal protein L10	Homo sapiens	137-140
19915642-3	2009	Electrostatic interactions between anions and positively charged amino acid residues supporting protein denaturation subsided in the line Cl- > NO3- > ClO4-.	perchlorate	157-161	NBL1, DAN family BMP antagonist	Homo sapiens	147-150
20126716-1	2010	The PF(6)(-) salt of a platinum(II) complex changes from yellow to red and becomes intensely luminescent upon exposure to aqueous ClO(4)(-).	perchlorate	130-135	sperm associated antigen 17	Homo sapiens	4-9
20162260-0	2010	Perchlorate in tap water, groundwater, surface waters, and bottled water from China and its association with other inorganic anions and with disinfection byproducts.	perchlorate	0-11	nuclear RNA export factor 1	Homo sapiens	15-18
20162260-7	2010	Mean concentrations of perchlorate in tap water, groundwater, surface waters, and bottled water were 2.46, 3.04, 2.82, and 0.22 microg l(-1), respectively.	perchlorate	23-34	nuclear RNA export factor 1	Homo sapiens	38-41
20449426-3	2010	The crystal structure of 1a as mixed ClO(4)(-) and PF(6)(-) salt of 1 shows a Co(III)N(5)S coordination geometry in which the pnt and phen showed N,S- and N,N-donor binding modes, respectively.	perchlorate	37-44	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	81-84
20066046-2	2010	Our experiments showed that CaV1.2 currents expressed in HEK293 cells are strongly inhibited by replacing extracellular chloride with gluconate or perchlorate.	perchlorate	147-158	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	28-34
19731653-2	2009	A potentially important source of ClO4- is past agricultural application of ClO4(-)-bearing natural NO3- fertilizer imported from the Atacama Desert, Chile, but evidence for this has been largely circumstantial.	perchlorate	34-38	NBL1, DAN family BMP antagonist	Homo sapiens	100-103
19499924-5	2009	Interestingly, whereas 2-OTf, 3-OTf, and 5-PF6 formed thermotropic metallogels mainly through van der Waals" forces with different emission colors, 1-X (X = OTf, BF4, PF6, and ClO4) showed additional Pt...Pt and pi-pi interactions to stabilize the resultant metallogels and showed drastic color changes during the gel-to-sol phase transition.	perchlorate	176-180	sperm associated antigen 17	Homo sapiens	43-46
19731653-2	2009	A potentially important source of ClO4- is past agricultural application of ClO4(-)-bearing natural NO3- fertilizer imported from the Atacama Desert, Chile, but evidence for this has been largely circumstantial.	perchlorate	76-83	NBL1, DAN family BMP antagonist	Homo sapiens	100-103
19620588-5	2009	MAIN OUTCOME MEASURES: Associations among the number of mutant alleles of SLC26A4; volume and texture of the thyroid; percentage of iodine 123 ((123)I) discharged at 120 minutes after administration of perchlorate in the perchlorate discharge test; and peripheral venous blood levels of thyrotropin, thyroxine, free thyroxine, triiodothyronine, thyroglobulin, antithyroid peroxidase and antithyroglobulin antibodies, and thyroid-binding globulin.	perchlorate	221-232	solute carrier family 26 member 4	Homo sapiens	74-81
27877278-10	2009	The introduction of a methyl group greatly modulates the electronic structure of the complex, i.e. (methyl-EDO-TTF)2X (X=BF4, ClO4) shows a two-dimensional electronic structure.	perchlorate	126-130	ras homolog family member H	Homo sapiens	111-114
18986218-9	2008	RESULTS: In Huh-7/AN cells, iodine was highly accumulated and completely blocked by perchlorate.	perchlorate	84-95	MIR7-3 host gene	Homo sapiens	12-17
19052257-6	2009	In vivo intestine-to-blood transport of pertechnetate, a NIS substrate, was sensitive to the NIS inhibitor perchlorate.	perchlorate	107-118	solute carrier family 5 member 5	Rattus norvegicus	57-60
19052257-6	2009	In vivo intestine-to-blood transport of pertechnetate, a NIS substrate, was sensitive to the NIS inhibitor perchlorate.	perchlorate	107-118	solute carrier family 5 member 5	Rattus norvegicus	93-96
19301335-2	2009	Depending on its affinity for the anions present, it can be isolated in its Co(III) (3)Co(II) (3) (m=3; e.g., 1(ClO(4))(3)) and Co(III) (2)Co(II) (4) (m=2; e.g., 1(BF(4))(2)n H(2)O) oxidation states.	perchlorate	112-119	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	79-82
19301335-2	2009	Depending on its affinity for the anions present, it can be isolated in its Co(III) (3)Co(II) (3) (m=3; e.g., 1(ClO(4))(3)) and Co(III) (2)Co(II) (4) (m=2; e.g., 1(BF(4))(2)n H(2)O) oxidation states.	perchlorate	112-119	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	87-93
19301335-2	2009	Depending on its affinity for the anions present, it can be isolated in its Co(III) (3)Co(II) (3) (m=3; e.g., 1(ClO(4))(3)) and Co(III) (2)Co(II) (4) (m=2; e.g., 1(BF(4))(2)n H(2)O) oxidation states.	perchlorate	112-119	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	76-83
19241193-5	2009	After being infected with AdPLEN, HepG2 cells (high AFP-expression hepatoma cells) showed 6 times greater perchlorate-sensitive (125)I uptake than did SMMC7721 cells (low/no AFP-expression hepatoma cells), 30 times higher than Hela (human cervix tumor cells), and noninfected HepG2 cells.	perchlorate	106-117	alpha fetoprotein	Homo sapiens	52-55
19235976-4	2009	The perchlorate frameworks 7, 8, or 9 react in an aqueous NH4+PF6- solution with formation of the related PF6--containing frameworks.	perchlorate	4-15	sperm associated antigen 17	Homo sapiens	62-65
19235976-4	2009	The perchlorate frameworks 7, 8, or 9 react in an aqueous NH4+PF6- solution with formation of the related PF6--containing frameworks.	perchlorate	4-15	sperm associated antigen 17	Homo sapiens	106-109
18687776-4	2009	Sortilin expression was demonstrated to be TSH dependent, both in FRTL-5 cells and in mice treated with methimazole and perchlorate.	perchlorate	120-131	sortilin 1	Rattus norvegicus	0-8
18993072-2	2008	The protein encoded by the Nce103 gene of Saccharomyces cerevisiae, a beta-carbonic anhydrase (CA, EC 4.2.1.1) designated as scCA, has been cloned, purified, characterized kinetically, and investigated for its inhibition with a series simple, inorganic anions such as halogenides, pseudohalogenides, bicarbonate, carbonate, nitrate, nitrite, hydrogen sulfide, bisulfite, perchlorate, sulfate, and some of its isosteric species.	perchlorate	371-382	carbonate dehydratase NCE103	Saccharomyces cerevisiae S288C	27-33
18259616-1	2008	A perchlorate ligand in the rare mu4-1,1,2,2 binding mode is seen for the first time as the sole support for the assembly of two cationic [Cu II 2L]+ fragments (H3L = a dinucleating ligand) in the formation of a magnetically-exchanged tetranuclear cluster.	perchlorate	2-13	H3 clustered histone 2	Homo sapiens	161-164
18553887-3	2008	Perchlorate has been found in dairy milk collected nationally and internationally.	perchlorate	0-11	Weaning weight-maternal milk	Bos taurus	36-40
18553887-10	2008	The perchlorate content of milk ranged from 0.9 to 10.3 microg/L and was similar to levels reported by the Food and Drug Administration"s Total Diet Study.	perchlorate	4-15	Weaning weight-maternal milk	Bos taurus	27-31
18553887-11	2008	The perchlorate content of milk was significantly related to the presence of perchlorate in feed but the variation of perchlorate in milk could not be explained by feed intake alone.	perchlorate	4-15	Weaning weight-maternal milk	Bos taurus	27-31
18553887-11	2008	The perchlorate content of milk was significantly related to the presence of perchlorate in feed but the variation of perchlorate in milk could not be explained by feed intake alone.	perchlorate	77-88	Weaning weight-maternal milk	Bos taurus	27-31
18553887-11	2008	The perchlorate content of milk was significantly related to the presence of perchlorate in feed but the variation of perchlorate in milk could not be explained by feed intake alone.	perchlorate	77-88	Weaning weight-maternal milk	Bos taurus	27-31
18447329-7	2008	Values of IC50 were calculated for the new platinum complexes cis-[Pt(C6F5)2(HmtpO)2] and [Pt(dmba)(PPh3)(HmtpO)]ClO4 against a panel of human tumor cell lines representative of ovarian (A2780 and A2780 cisR), lung (NCI-H460), and breast cancers (T47D).	perchlorate	113-117	protein phosphatase 4 catalytic subunit	Homo sapiens	100-104
18275142-4	2008	Removing Phe(-) from Delta-1 and Lambda-1 using perchloric acid gave two enantiomers of [Ni(alpha-SS-L)](ClO4)2 (S-3) and [Ni(alpha-RR-L)](ClO4)2 (R-3).	perchlorate	105-109	delta like non-canonical Notch ligand 1	Homo sapiens	21-28
18698765-6	2008	In contrast to the 2(Ar(X)) cases, the HHPP-adduct 2(H) reacted to give a copper(II)-acetate complex [Cu(II)(L(H))(OAc)](ClO4) (6(H)), in which one of the oxygen atoms of the acetate co-ligand originated from H2O2.	perchlorate	121-125	HHPP	Homo sapiens	39-43
18077370-0	2007	The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate.	perchlorate	98-109	solute carrier family 5 member 5	Homo sapiens	4-19
18163611-1	2008	1-methyl-5-aminotetrazole (4, MAT) can easily be protonated by strong acids, yielding known but largely uninvestigated 1-methyl-5-aminotetrazolium nitrate (4a) and perchlorate (4b).	perchlorate	164-175	methionine adenosyltransferase 1A	Homo sapiens	30-33
18173265-3	2008	Ferroelectricity of its analogue, (Lig)(2)Tb(D(2)O)(2)(ClO(4)) (2), further confirms the presence of the ferroelectric deuterium effect.	perchlorate	55-62	ubiquitin conjugating enzyme E2 K	Homo sapiens	35-38
18173267-3	2008	The reaction of [Mn3O(O2CMe)6(py)3](ClO4) with 3 equiv of dapdoH2 (with or without 2 equiv of NEt3) in MeOH gave 1.	perchlorate	36-40	tetraspanin 2	Homo sapiens	94-98
18077370-0	2007	The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate.	perchlorate	98-109	solute carrier family 5 member 5	Homo sapiens	21-24
18077370-4	2007	Perchlorate (ClO(4)(-)) is a well known competitive inhibitor of NIS.	perchlorate	0-11	solute carrier family 5 member 5	Homo sapiens	65-68
18077370-4	2007	Perchlorate (ClO(4)(-)) is a well known competitive inhibitor of NIS.	perchlorate	13-22	solute carrier family 5 member 5	Homo sapiens	65-68
18077370-6	2007	To date, it is still uncertain whether ClO(4)(-) is a NIS blocker or a transported substrate of NIS.	perchlorate	39-46	solute carrier family 5 member 5	Homo sapiens	54-57
18077370-7	2007	Here we show in vitro and in vivo that NIS actively transports ClO(4)(-), including ClO(4)(-) translocation to the milk.	perchlorate	63-69	solute carrier family 5 member 5	Homo sapiens	39-42
18077370-7	2007	Here we show in vitro and in vivo that NIS actively transports ClO(4)(-), including ClO(4)(-) translocation to the milk.	perchlorate	84-90	solute carrier family 5 member 5	Homo sapiens	39-42
18077370-9	2007	Strikingly, the Na(+)/ ClO(4)(-) transport stoichiometry is electroneutral, uncovering that NIS translocates different substrates with different stoichiometries.	perchlorate	23-28	solute carrier family 5 member 5	Homo sapiens	92-95
17547680-1	2007	BACKGROUND: Iodide organification defects are frequently but not always associated with mutations in the thyroid peroxidase (TPO) gene and characterized by a positive perchlorate discharge test.	perchlorate	167-178	thyroid peroxidase	Homo sapiens	105-123
17318546-12	2007	Perchlorate test revealed a total iodide organification defect in two patients, including one with a neonatal diagnosis of Pendred"s syndrome, who were subsequently found to harbour TPO mutations.	perchlorate	0-11	thyroid peroxidase	Homo sapiens	182-185
17531245-0	2007	Preparation, characterization, and CuX2 and CoX2 (X=Cl-, Br-, ClO-4) adsorption behavior of a polyhedral oligomer silsesquioxane functionalized with an organic base.	perchlorate	62-67	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	44-48
18083933-6	2007	Yet common actions of the RyR-specific agents perchlorate, dantrolene Na, ryanodine, caffeine, adenosine 3",5"-cyclic diphosphate ribose (cADPr) and ruthenium red implicate RyR in signaling in all these cell types.	perchlorate	46-57	ryanodine receptor 1	Homo sapiens	26-29
17547680-1	2007	BACKGROUND: Iodide organification defects are frequently but not always associated with mutations in the thyroid peroxidase (TPO) gene and characterized by a positive perchlorate discharge test.	perchlorate	167-178	thyroid peroxidase	Homo sapiens	125-128
17607730-0	2007	Effects of perchlorate on sodium-iodide symporter and pendrin gene expression in deer mice.	perchlorate	11-22	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	26-49
17607730-0	2007	Effects of perchlorate on sodium-iodide symporter and pendrin gene expression in deer mice.	perchlorate	11-22	solute carrier family 26, member 4	Mus musculus	54-61
17607730-7	2007	Several factors could influence the effect of perchlorate exposure on NIS and pendrin gene expression in the stomach and kidney, including (1) pre-exposure to trace perchlorate through food and water perhaps resulting in adaptation (or tolerance) in these animals; (2) metabolism of perchlorate in deer mice causing only 46-61% perchlorate excreted into urine.	perchlorate	46-57	solute carrier family 5 (sodium iodide symporter), member 5	Mus musculus	70-73
17607730-7	2007	Several factors could influence the effect of perchlorate exposure on NIS and pendrin gene expression in the stomach and kidney, including (1) pre-exposure to trace perchlorate through food and water perhaps resulting in adaptation (or tolerance) in these animals; (2) metabolism of perchlorate in deer mice causing only 46-61% perchlorate excreted into urine.	perchlorate	46-57	solute carrier family 26, member 4	Mus musculus	78-85
17723386-5	2006	In the present study, the long-term stability of perchlorate ion in deionized water, tap water, ground water, and surface water was examined.	perchlorate	49-60	nuclear RNA export factor 1	Homo sapiens	85-88
17378593-2	2007	We show that the rate of electron transfer from ascorbate to the surface-confined Fc+ decreases with increasing n. The rationale for the dependence of the rate of electrocatalytic activity and n, in the presence of ClO4, is obtained from Fourier-transform surface-enhanced Raman spectroscopy (FT-SERS), cyclic voltammetry, and electrochemical quartz crystal microbalance (EQCM) data.	perchlorate	215-219	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	296-300
17378593-3	2007	In particular, FT-SERS shows decreasing amounts of surface-bound ClO4- upon oxidation of the ferrocene with decreasing n, while EQCM data show the effective electrode mass increase was consistently higher on the shorter chain SAMs.	perchlorate	65-69	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	18-22
17378593-7	2007	Increased hydration of the Fc+ impedes the formation of Fc+-ClO4- ion pairs (EQCM and FT-SERS data), which, consequently, accelerates the electrocatalytic electron transfer from the solution-dissolved ascorbate.	perchlorate	60-64	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	89-93
17257840-7	2007	hCA XIV was on the other hand weakly inhibited by fluoride and not at all inhibited by perchlorate, but showed good affinity for most other anions investigated here.	perchlorate	87-98	carbonic anhydrase 14	Homo sapiens	0-7
17140667-1	2007	One new binuclear Co(II) complex of N,N,N",N"-tetrakis(2-benzimidazolylmethyl)-2-hydroxyl-1,3-diaminopropane (HL), [Co(2)L(mu(2)-Cl)](ClO(4))(2) x 3CH(3)CN x C(2)H(5)OC(2)H(5) (1), has been synthesized and its crystal structure and magnetic properties are shown.	perchlorate	134-141	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	18-24
17180336-8	2007	Application of the electrodes to determine perchlorate in tap water and human urine is also reported.	perchlorate	43-54	nuclear RNA export factor 1	Homo sapiens	58-61
16711692-1	2006	Reactions of 9,10-bis(diphenylphosphino)anthracene (PAnP) and AgX (X = OTf-, ClO4-, PF6-, and BF4-) led to luminescent Ag-PAnP complexes with rich structural diversity.	perchlorate	77-81	PILR alpha associated neural protein	Homo sapiens	52-56
15941870-5	2005	RESULTS: hNIS-transfected TT cells showed perchlorate-sensitive iodide uptake, accumulating 125-I about 12-fold in vitro with organification of 4% of accumulated iodide resulting in a significant decrease in iodide efflux.	perchlorate	42-53	solute carrier family 5 member 5	Homo sapiens	9-13
16322276-1	2006	BACKGROUND: Iodide organification defects are associated with mutations in the dual oxidase 2 (DUOX2) gene and are characterized by a positive perchlorate discharge test.	perchlorate	143-154	dual oxidase 2	Homo sapiens	79-93
16322276-1	2006	BACKGROUND: Iodide organification defects are associated with mutations in the dual oxidase 2 (DUOX2) gene and are characterized by a positive perchlorate discharge test.	perchlorate	143-154	dual oxidase 2	Homo sapiens	95-100
16289343-15	2006	Only methimazole and perchlorate showed significant changes in TRalpha gene expression in the brain whereas PTU did not suggesting differences in cellular mechanisms of action.	perchlorate	21-32	T cell receptor alpha locus L homeolog	Xenopus laevis	63-70
16187904-2	2005	We tested the hypothesis that long-term exposure to perchlorate at these levels may cause a situation analogous to iodine deficiency, thus causing increases in thyrotropin (TSH) and thyroglobulin (Tg) levels and decreased levels of free thyroxine (FT4), in either the mother during the early stages of gestation or the neonate at birth, or in the fetus cause growth retardation.	perchlorate	52-63	thyroglobulin	Homo sapiens	182-195
16570594-10	2006	Processes in the soils that may have depleted atmospherically derived NO3-also may have depleted ClO4- to varying degrees prior to recharge.	perchlorate	97-101	NBL1, DAN family BMP antagonist	Homo sapiens	70-73
16130774-2	2005	With respect to the identity of the supporting electrolyte, the elution strength of the electrolyte anion increased as F- < OH- < BF4- < ClO4- < PF6- for injections of negatively charged aromatic molecules, whereas a 10-fold increase in electrolyte concentration induced a 60% change in retention for the same solutes.	perchlorate	146-150	sperm associated antigen 17	Homo sapiens	157-160
15934752-1	2005	1,5-Diamino-1H-tetrazole (2, DAT) can easily be protonated by reaction with strong mineral acids, yielding the poorly investigated 1,5-diaminotetrazolium nitrate (2a) and perchlorate (2b).	perchlorate	171-182	solute carrier family 6 member 3	Homo sapiens	29-32
15852127-1	2005	One-pot reaction of CuX2 salts (X = NO3, Cl, ClO4, AcO, SO(4)/2), 2-Hydroxypyrimidine hydrochloride (2-Hpymo.HCl) and 4,4"-bipyridine (4,4"-bpy), in H2O : ethanol : ammonia (20 : 10 : 5) solution, leads to isomorphous extended layered materials of type [Cu3(mu-OH)2(mu-Cl)2(mu-2-pymo)(mu-4,4"-bpy)3]nXn.mH2O (X = NO3 (1a), Cl (1b), ClO4 (1c), AcO (1d), SO(4)/2 (1e)).	perchlorate	45-49	cut like homeobox 2	Homo sapiens	20-24
15819249-5	2005	Thus, the anions were ranked SO4(2-) > Cl- > or = ClO4- > NO3- > HCO3 (from most enhanced to most inhibited) in their influence on granular iron reactivity toward 4ClNB.	perchlorate	56-60	NBL1, DAN family BMP antagonist	Homo sapiens	67-70
15830949-8	2005	The ion pair formation constants show a clear trend with the order being: PF6- > ClO4- > CF3COO- > Cl-.	perchlorate	84-88	sperm associated antigen 17	Homo sapiens	74-77
15683794-4	2005	Compared with perchlorate solutions, the positive peak of nitrate solutions has a red shift of about 20 cm(-1) and the peak area is about half of that of perchlorate solutions with the same concentrations, indicating that the hydrogen bonding between NO3- and water monomers is relative stronger than that between ClO4- and water monomers, and NO3- has a strict requirement on the orientation of water molecules when hydrogen bonded with water monomers due to its planar structure.	perchlorate	14-25	NBL1, DAN family BMP antagonist	Homo sapiens	251-254
15730274-6	2005	Tetraalkylammonium hexafluorophosphate, tetrafluoroborate, and perchlorate supporting electrolytes prevent the encapsulation of Cob+, while tetraalkylammonium chloride and bromide salts allow it.	perchlorate	63-74	metabolism of cobalamin associated B	Homo sapiens	128-131
15683794-4	2005	Compared with perchlorate solutions, the positive peak of nitrate solutions has a red shift of about 20 cm(-1) and the peak area is about half of that of perchlorate solutions with the same concentrations, indicating that the hydrogen bonding between NO3- and water monomers is relative stronger than that between ClO4- and water monomers, and NO3- has a strict requirement on the orientation of water molecules when hydrogen bonded with water monomers due to its planar structure.	perchlorate	154-165	NBL1, DAN family BMP antagonist	Homo sapiens	251-254
15683794-4	2005	Compared with perchlorate solutions, the positive peak of nitrate solutions has a red shift of about 20 cm(-1) and the peak area is about half of that of perchlorate solutions with the same concentrations, indicating that the hydrogen bonding between NO3- and water monomers is relative stronger than that between ClO4- and water monomers, and NO3- has a strict requirement on the orientation of water molecules when hydrogen bonded with water monomers due to its planar structure.	perchlorate	314-318	NBL1, DAN family BMP antagonist	Homo sapiens	251-254
15679404-2	2005	L1 and L2 form mononuclear Cu(II) complexes [Cu(L)(Cl)](ClO4) [L = L1 (1) and L2 (2)], respectively.	perchlorate	56-60	L1 cell adhesion molecule	Homo sapiens	0-9
15679404-2	2005	L1 and L2 form mononuclear Cu(II) complexes [Cu(L)(Cl)](ClO4) [L = L1 (1) and L2 (2)], respectively.	perchlorate	56-60	immunoglobulin kappa variable 1-6	Homo sapiens	67-80
15690431-7	2005	In the presence of ClO4- as EOF adjustor, the separation of a mixture containing four basic proteins (lysozyme, cytochrome c, alpha-chymotrypsinogen A, and myoglobin) yielded efficiencies of 204,000-896,000 plates/m and recoveries of 88%-98%.	perchlorate	19-23	cytochrome c, somatic	Homo sapiens	112-124
15664814-4	2005	Isozymes hCA I and II are best inhibited by chlorate, perchlorate, and silicate, together with the anions structurally related to sulfate, sulfamate, and sulfamidate, but sulfate itself is a weak inhibitor (inhibition constant of 74 mM against hCA I and 183 mM against hCA II).	perchlorate	54-65	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	9-21
15664814-4	2005	Isozymes hCA I and II are best inhibited by chlorate, perchlorate, and silicate, together with the anions structurally related to sulfate, sulfamate, and sulfamidate, but sulfate itself is a weak inhibitor (inhibition constant of 74 mM against hCA I and 183 mM against hCA II).	perchlorate	54-65	HCA1	Homo sapiens	9-12
15664814-4	2005	Isozymes hCA I and II are best inhibited by chlorate, perchlorate, and silicate, together with the anions structurally related to sulfate, sulfamate, and sulfamidate, but sulfate itself is a weak inhibitor (inhibition constant of 74 mM against hCA I and 183 mM against hCA II).	perchlorate	54-65	carbonic anhydrase 2	Homo sapiens	269-275
15347726-9	2004	Iodine uptake of SK-Hep1-NIS is completely blocked by perchlorate.	perchlorate	54-65	DNL-type zinc finger	Homo sapiens	20-24
15499918-7	2004	The following trend in increase of basic analyte retention factor and decrease of tailing factor was found: PF6- > ClO4- approximately BF4- > H2PO4-.	perchlorate	118-122	sperm associated antigen 17	Homo sapiens	108-111
15356757-2	2004	Thus, the reaction of Zn(ClO4)2.6H2O with L1-3 in acetonitrile affords [(L)Zn](ClO4)2(L=L1, 1; L2, 2) and [(L3)Zn(H2O)(NCCH3)](ClO4)2 3.	perchlorate	25-29	immunoglobulin kappa variable 2-4 (pseudogene)	Homo sapiens	42-46
15279074-9	2004	All patients harbouring mutations in the SLC26A4 gene had goiter and a positive perchlorate discharge test: 3 were slightly hypothyroid and 2 euthyroid.	perchlorate	80-91	solute carrier family 26 member 4	Homo sapiens	41-48
15279074-12	2004	Patients with mutations in the SLC26A4 gene had larger thyroid volume (p<0.002), higher serum thyroglobulin (Tg) levels (p<0.002) and greater radioiodine discharge after perchlorate (p=0.09) than patients without mutations.	perchlorate	176-187	solute carrier family 26 member 4	Homo sapiens	31-38
15026288-2	2004	ATR-IR is amongst the rare techniques which allow to analyze the sorption phenomena in situ and led to several results about the speciation of sorbed anions (sulfate, carbonate, phosphate, perchlorate, ...) or ternary inorganic complexes since it is able to distinguish outer-sphere and inner-sphere complexes.	perchlorate	189-200	ATR serine/threonine kinase	Homo sapiens	0-3
12693042-1	2002	Low pressure flash thermolysis of different precursor molecules containing-ClO, -ClO3 or -OClO3 yield, when highly diluted in Ne or O2 and subsequent quenching of the products in a matrix at 5 or 15 K, ClOx (x = 1, 3, 4) radicals, respectively.	perchlorate	90-95	cut like homeobox 1	Homo sapiens	202-206
14751036-2	2003	The objective of this study was to screen and subsequently identify TPO gene mutations in patients with congenital hypothyroidism with evidence of total iodine organification defects (TIOD) or partial iodine organification defect (PIOD) as defined by the perchlorate discharge test.	perchlorate	255-266	thyroid peroxidase	Homo sapiens	68-71
12844302-4	2003	The presence of the syn isomer in solution, independent of the counterion employed (perchlorate or thiocyanate), accounts for the effectiveness of the barium(II) ion as a template agent in the synthesis of the lateral macrobicycles resulting from the condensation of L(2) with different dicarbonyl compounds.	perchlorate	84-95	synemin	Homo sapiens	20-23
12769589-6	2003	There are therefore two microscopically distinct kinds of Co(350) complexes, those with DNA and those with ClO(4)(-) counterions, with respect to their Co(II/I) electron-transfer dynamics, leading to percolative behavior in their mixtures.	perchlorate	107-114	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	152-159
12769589-9	2003	We conclude that the measured Co(II/I) charge transport and electron-transfer rate constants reflect more the diffusive mobility of the perchlorate counterion than the intrinsic Co(II/I) electron hopping rate.	perchlorate	136-147	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	30-37
12489024-6	2003	Perchlorate-sensitive (125)I uptake in multiple cell lines was demonstrated following transduction with retroviral vectors expressing either the human or rNIS gene.	perchlorate	0-11	solute carrier family 5 member 5	Rattus norvegicus	154-158
14658894-6	2003	The onset of the second spin-transition of the ClO4- (1) and BF4- (2) salts adjoins the first spin-transition, while a mixed (HS-[FeIIH3L(Me)](2+) + LS-[FeIIL(Me)]-) spin-state spans a temperature range as wide as 70 K for salts 3-5 with larger counteranions, PF6-, AsF6-, and SbF6-, respectively.	perchlorate	47-51	sperm associated antigen 17	Homo sapiens	260-263
14587717-1	2003	Reaction of the bis-bidentate ligand L1, having two bidentate pyrazolyl-pyridine termini, with Co(II) or Zn(II) results in formation of the complexes [M8(L1)12]X16 (X = perchlorate or tetrafluoroborate); [Zn8(L1)2](ClO4)16 has been structurally characterised and is a cube with a metal ion at each corner, a bridging ligand along each edge, and an anion in the central cavity.	perchlorate	169-180	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	95-101
11929962-3	2002	In contrast, reaction of L(1) and L(2) with Co(II) salts, followed by treatment with tetrafluoroborate or perchlorate, results in assembly of cage complexes having a 4:6 metal:ligand ratio; these complexes have a metal ion at each corner of an approximate tetrahedron, and a bis-bidentate bridging ligand spanning each edge.	perchlorate	106-117	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	44-50
12230211-3	2002	In the absence of nitrate, perchlorate removal rate (rp, ppb/min) in the reactor was found to be first order with respect to perchlorate concentration (c, ppb) according to rp = 0.16 +/- 0.06c(0.97+/-0.12) (n = 11, R2 = 0.97, p < 10(-5)).	perchlorate	27-38	histatin 1	Homo sapiens	57-60
12230211-3	2002	In the absence of nitrate, perchlorate removal rate (rp, ppb/min) in the reactor was found to be first order with respect to perchlorate concentration (c, ppb) according to rp = 0.16 +/- 0.06c(0.97+/-0.12) (n = 11, R2 = 0.97, p < 10(-5)).	perchlorate	27-38	histatin 1	Homo sapiens	155-158
12230211-3	2002	In the absence of nitrate, perchlorate removal rate (rp, ppb/min) in the reactor was found to be first order with respect to perchlorate concentration (c, ppb) according to rp = 0.16 +/- 0.06c(0.97+/-0.12) (n = 11, R2 = 0.97, p < 10(-5)).	perchlorate	125-136	histatin 1	Homo sapiens	57-60
12230211-3	2002	In the absence of nitrate, perchlorate removal rate (rp, ppb/min) in the reactor was found to be first order with respect to perchlorate concentration (c, ppb) according to rp = 0.16 +/- 0.06c(0.97+/-0.12) (n = 11, R2 = 0.97, p < 10(-5)).	perchlorate	125-136	histatin 1	Homo sapiens	155-158
12230211-6	2002	Perchlorate was removed by an average of 25 +/- 5% from a perchlorate-contaminated groundwater containing 73 +/- 2 ppb of perchlorate and 21 +/- 2 ppm of nitrate.	perchlorate	0-11	histatin 1	Homo sapiens	115-118
12230211-6	2002	Perchlorate was removed by an average of 25 +/- 5% from a perchlorate-contaminated groundwater containing 73 +/- 2 ppb of perchlorate and 21 +/- 2 ppm of nitrate.	perchlorate	58-69	histatin 1	Homo sapiens	115-118
12022843-2	2002	The response times were strongly influenced by the nature of the counterion: small anions (BF(4)(-) and ClO(4)(-)) led to relatively fast transients, while large anions (PF(6)(-), AsF(6)(-)) produced a slow time-response.	perchlorate	104-110	arylsulfatase F	Homo sapiens	180-183
12175221-1	2002	The reaction between 2-(hydroxyethyl)pyridine (hepH) and a 2:1 molar mixture of [Mn3O(O2CMe)6(py)3](ClO4) and [Mn3O(O2CMe)6(py)3](py) in MeCN leads to isolation of [Mn18O14(O2CMe)18(hep)4(hepH)2(H2O)2](ClO4)2 (1) in 10% yield.	perchlorate	100-104	hephaestin	Homo sapiens	47-51
11862551-5	2002	Next, application of Selwyn"s test of enzyme inactivation was applied to progress curves and reveals that the addition of tetrahedral oxyanions (50 mM sulfate, phosphate or perchlorate) allows the control of ArsC stability and essentially eliminates the biphasic character of the Michaelis-Menten curves.	perchlorate	173-184	Arsenate reductase	Staphylococcus aureus	208-212
12007092-1	2002	A combined experimental and theoretical study of the paramagnetic [Co(II)(C12H20N8)(H2O)2] x 2 ClO4 complex was made on the basis of the electron density distribution and topological analysis.	perchlorate	95-99	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	67-73
11874116-1	2002	Coimmobilization of beta-galactosidase and glucose oxidase in a redox polymer, polyvinylferrocenium perchlorate (PVF+ ClO4-), led to the development of an enzyme electrode for the determination of lactose.	perchlorate	118-123	galactosidase beta 1	Homo sapiens	20-38
11990591-4	2001	The ion-sensitive field-effect transistor showed a linear potential response ranging in the I- concentration between 1.0 x 10(-5) and 1.0 x 10(-1) M. The selectivity coefficients for I- towards interferences of ClO4- and NO3- were estimated to be Kpot(I-,ClO4-) approximately 6.2 x 10(-4) and Kpot(I-,No3-) approximately 4.9 x 10(-4).	perchlorate	211-215	NBL1, DAN family BMP antagonist	Homo sapiens	221-224
11990591-4	2001	The ion-sensitive field-effect transistor showed a linear potential response ranging in the I- concentration between 1.0 x 10(-5) and 1.0 x 10(-1) M. The selectivity coefficients for I- towards interferences of ClO4- and NO3- were estimated to be Kpot(I-,ClO4-) approximately 6.2 x 10(-4) and Kpot(I-,No3-) approximately 4.9 x 10(-4).	perchlorate	211-215	NBL1, DAN family BMP antagonist	Homo sapiens	301-304
11306668-16	2001	This was accompanied by a negative (approximately 10-15 mV) shift in the steady-state charge-voltage relationship but an otherwise conserved maximum charge, Q(max), and steepness factor, k, in parallel with previously reported effects of perchlorate following treatments with RyR-specific agents.	perchlorate	238-249	ryanodine receptor 2	Homo sapiens	276-279
11517148-7	2001	Na(+)/I(-) symporter mRNA was detected in the fetal thyroid of supplemented with iodide and increased about 2- and 4- fold in the thyroid of fetuses from a low iodine diet, not supplemented, and one supplemented with perchlorate, respectively.	perchlorate	217-228	solute carrier family 5 member 5	Rattus norvegicus	0-20
11517148-8	2001	Na(+)/I(-) symporter expression was induced in the fetal side of the placenta in both a low iodine diet, not supplemented, and one supplemented with perchlorate; in contrast, Na(+)/I(-) symporter mRNA was never detected in the maternal side of the placenta.	perchlorate	149-160	solute carrier family 5 member 5	Rattus norvegicus	0-20
11254038-1	2000	The use of a new FAIMS prototype and waveform generator, along with the use of a mixed carrier gas, in this electrospray ionisation (ESI)-FAIMS-mass spectrometry (MS) study gave a detection limit for perchlorate in a relatively "clean" matrix of tap water of 0.050 ppb.	perchlorate	200-211	nuclear RNA export factor 1	Homo sapiens	246-249
11300810-1	2001	(1/2)H2O and in the spin crossover complexes [Co(II)(terpy)2]X2.nH2O (X = Cl and ClO4): a Mossbauer emission spectroscopic study.	perchlorate	81-85	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	46-51
11228531-2	2000	We observed perchlorate-inhibitable iodide uptake up to 41-fold over control in all NIS-transfected cells.	perchlorate	12-23	solute carrier family 5 member 5	Homo sapiens	84-87
11196947-3	2000	In the complex ions of the equilibrium [CuI(mmb)2](+) + ClO4- reversible e- + [CuII(mmb)2-(eta 1-ClO4)]+ the almost linear N-Cu-N backbone is invariant whereas the bonds to the thioether sulfur centers and especially the changing S-Cu-S angle (145.18(5) degrees for the CuII species, 109.33(3) degrees for the CuI form) reflect the metal oxidation state.	perchlorate	56-60	secreted phosphoprotein 1	Homo sapiens	91-96
11179391-5	2001	Under symmetrical ionic conditions, wild-type CFTR channels showed the conductance sequence Cl- > NO3- > Br- > or = formate > F- > SCN- congruent to ClO4-.	perchlorate	164-168	CF transmembrane conductance regulator	Homo sapiens	46-50
11179391-10	2001	Chloride currents through CFTR channels were blocked by low concentrations (10 mM) of SCN-, I- and ClO4-, implying relatively tight binding of these anions within the pore.	perchlorate	99-103	CF transmembrane conductance regulator	Homo sapiens	26-30
10767759-6	2000	Also, certain Co(II) and Fe(II) ion pair complexes undergo oxidation reactions in which species such as dioxygen and nitric oxide from the counterions ClO4- and NO3- are transferred to the Co(II) and Fe(II) complexes, showing the inherent affinity of these metals for these molecules.	perchlorate	151-155	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	14-20
10981498-3	2000	I- and ClO4- were also found to inhibit CFTR currents, but both were less effective than HCO3-.	perchlorate	7-11	ATP-binding cassette sub-family C member 7	Cavia porcellus	40-44
10902795-8	2000	The positivity of a perchlorate discharge test and the malformations of membranous labyrinth fit well with the recent achievements on the role of pendrin in thyroid hormonogenesis and the maintenance of endolymph homeostasis.	perchlorate	20-31	solute carrier family 26 member 4	Homo sapiens	146-153
10767759-6	2000	Also, certain Co(II) and Fe(II) ion pair complexes undergo oxidation reactions in which species such as dioxygen and nitric oxide from the counterions ClO4- and NO3- are transferred to the Co(II) and Fe(II) complexes, showing the inherent affinity of these metals for these molecules.	perchlorate	151-155	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	189-195
10232600-9	1999	Prostate cells transfected with NIS/PSA-pEGFP-1 showed perchlorate-sensitive, androgen-dependent iodide uptake in a range comparable to that observed in control cell lines transfected with hNIS cDNA.	perchlorate	55-66	solute carrier family 5 member 5	Homo sapiens	32-35
10655630-6	2000	The method detection limit for perchlorate based on 3.14 sigma n-1 of seven replicate injections was 100 ng L-1 (parts per trillion).	perchlorate	31-42	immunoglobulin kappa variable 1-16	Homo sapiens	108-111
11207750-10	1999	In addition to chlorate, strain CKB can also couple acetate oxidation to the reduction of oxygen or perchlorate.	perchlorate	100-111	creatine kinase B	Homo sapiens	32-35
11207750-13	1999	Strain CKB can grow in chlorate and perchlorate concentrations of 80 or 20 mM respectively.	perchlorate	36-47	creatine kinase B	Homo sapiens	7-10
10233076-7	1999	The effectiveness of the anions in reducing the dipole potential was found to be ClO4- > SCN- > I- > NO3- > Br- > Cl- > F- > SO42-.	perchlorate	81-85	NBL1, DAN family BMP antagonist	Homo sapiens	110-113
10468986-1	1999	OBJECTIVE: To screen and subsequently sequence the TPO gene for mutations in patients with congenital goitre, hypothyroidism and evidence for an organification defect (positive perchlorate discharge test).	perchlorate	177-188	thyroid peroxidase	Homo sapiens	51-54
9513813-9	1998	The presence of two conformational forms of IFN gamma in perchlorate solution is evidenced from an isofluorescent point at 315 nm.	perchlorate	57-68	interferon gamma	Homo sapiens	44-53
9549759-1	1998	Perchlorate competitively blocks iodide from entering the thyroid by an effect on the Na+/I- symporter thus preventing the further synthesis of thyroid hormone but has no effect on the iodination process itself.	perchlorate	0-11	solute carrier family 5 member 5	Homo sapiens	86-102
9513813-14	1998	Similarities of the protein fluorescence and 1-anilino-8-naphthalene-sulfonic-acid (ANS) binding properties of the protein in NaClO4 and acid solutions indicate that IFN gamma also exists in a molten globule-like state in perchlorate solution at neutral pH.	perchlorate	222-233	interferon gamma	Homo sapiens	166-175
9341168-6	1997	NIS was capable of transporting a wide variety of anions (I-, ClO3-, SCN-, SeCN-, NO3-, Br-, BF4-, IO4-, BrO3-, but perchlorate (ClO4-) was not transported.	perchlorate	116-127	solute carrier family 5 member 5	Rattus norvegicus	0-3
9503332-14	1998	Perchlorate similarly reversed the positive shift in the transition potential of the q gamma component that was brought about by such RyR modification (from V* approximately -40 mV back to V* approximately -60 mV).	perchlorate	0-11	ryanodine receptor 1	Homo sapiens	134-137
9359907-5	1997	Perchlorate both increased ryanodine binding to MHS and normal SR vesicles and increased single-channel open probability of the purified MHS and normal RyR.	perchlorate	0-11	ryanodine receptor 2	Homo sapiens	152-155
9414487-3	1998	The catalytic efficiency of the complexes for dismutation of superoxide radicals depends on the particular anion liganded to Cu(II) ion in the complexes, and the order of potency was observed to be ClO4 > Cl > NO3 in phosphate buffer at pH 7.40.	perchlorate	198-202	NBL1, DAN family BMP antagonist	Homo sapiens	216-219
9374644-2	1997	Frog muscle had two distinct types of RyRs in the SR: one showed a bell-shaped channel activation curve against cytoplasmic Ca2+ or niflumic acid, and its mean open probability (Po) was increased by perchlorate at 20-30 mM (termed "alpha-like" RyR); the other showed a sigmoidal activation curve against Ca2+ or niflumic acid, with no effect on perchlorate (termed "beta-like" RyR).	perchlorate	199-210	ryanodine receptor 1	Homo sapiens	38-41
9374644-2	1997	Frog muscle had two distinct types of RyRs in the SR: one showed a bell-shaped channel activation curve against cytoplasmic Ca2+ or niflumic acid, and its mean open probability (Po) was increased by perchlorate at 20-30 mM (termed "alpha-like" RyR); the other showed a sigmoidal activation curve against Ca2+ or niflumic acid, with no effect on perchlorate (termed "beta-like" RyR).	perchlorate	199-210	ryanodine receptor 1	Homo sapiens	244-247
9341168-6	1997	NIS was capable of transporting a wide variety of anions (I-, ClO3-, SCN-, SeCN-, NO3-, Br-, BF4-, IO4-, BrO3-, but perchlorate (ClO4-) was not transported.	perchlorate	129-133	solute carrier family 5 member 5	Rattus norvegicus	0-3
9070882-0	1997	Different electrophysiological character of I-, ClO4-, and SCN- in the transport by Na+/I- symporter.	perchlorate	48-52	solute carrier family 5 member 5	Rattus norvegicus	84-100
9305876-10	1997	The cloned RyR3 was activated by ATP, caffeine, and perchlorate, inhibited by Mg2+ and ruthenium red, and modified by ryanodine.	perchlorate	52-63	ryanodine receptor 3	Homo sapiens	11-15
9270719-4	1997	Perchlorate and thiocyanate, inhibitors of the iodide transporter, also abolish the PRL effects on iodide uptake and incorporation.	perchlorate	0-11	prolactin	Mus musculus	84-87
9046106-3	1997	Some copper (II) complexes [CuL2] with SOD-like activity containing 2-methyl amino pyridine and various anions (Cl-, Br-, NO3-, ClO4-, or SO4--) were tested for their protective efficiency toward the cell damage photoinduced by CPBA.	perchlorate	128-132	cullin 2	Homo sapiens	28-32
9070882-12	1997	Surprisingly, the perfusion of ClO-4 did not induce an inward current, indicating that ClO-4 bound to the Na+/I- symporter, but was not carried by it, or that one ClO-4 ion was carried with one Na+ ion.	perchlorate	87-92	solute carrier family 5 member 5	Rattus norvegicus	106-122
9070882-12	1997	Surprisingly, the perfusion of ClO-4 did not induce an inward current, indicating that ClO-4 bound to the Na+/I- symporter, but was not carried by it, or that one ClO-4 ion was carried with one Na+ ion.	perchlorate	87-92	solute carrier family 5 member 5	Rattus norvegicus	106-122
11666437-4	1996	The molecular composition of a transient blue species derived from the reaction of [Fe(2)O(TPA)(2)(H(2)O)(ClO(4))](ClO(4))(3) with excess benzyl alcohol and (t)BuOOH at -40 degrees C was also determined.	perchlorate	106-113	plasminogen activator, tissue type	Homo sapiens	91-94
8806637-4	1996	Transient expression of the hNIS cDNA conferred perchlorate-sensitive iodide uptake to a nonthyroid cell line, COS-7.	perchlorate	48-59	solute carrier family 5 member 5	Homo sapiens	28-32
7809008-2	1994	The calcium channel agonist, perchlorate (ClO4-, 12 mmol/L), augmented both 45Ca2+ uptake and insulin release from normal islets in the presence of 20 but not 1 mmol/L glucose.	perchlorate	29-40	insulin	Cricetulus griseus	94-101
7483671-5	1995	Reaction of the BP, 6-FBP, 6-ClBP and 6-BrBP radical cation perchlorates with H2O produced BP 1,6-, 3,6- and 6,12- dione, whereas 6-CH3BP.+ClO4-.AgI yielded 6-CH2OHBP.	perchlorate	139-143	ECB2	Homo sapiens	22-25
7483671-7	1995	When BP.+ClO4-.AgI and 6-FBP.+ClO4-.AgI were reacted with NaOAc in H2O/CH3CN (9:1), 6-OAcBP was formed, in addition to the quinones.	perchlorate	30-34	ECB2	Homo sapiens	25-28
7809008-2	1994	The calcium channel agonist, perchlorate (ClO4-, 12 mmol/L), augmented both 45Ca2+ uptake and insulin release from normal islets in the presence of 20 but not 1 mmol/L glucose.	perchlorate	42-46	insulin	Cricetulus griseus	94-101
1379724-6	1992	Similarly, thiocyanate and perchlorate were the only chaotropic ions tested that increased the initial slope and amplitude of the extracellularly recorded potentials evoked in CA1 dendritic field.	perchlorate	27-38	carbonic anhydrase 1	Homo sapiens	176-179
8386593-1	1993	The fluorescence method was used to investigate the effect of inorganic anions, SCN-, I-, ClO4- and Br- on the binding of thyroxine (T4) by bovine serum albumin (BSA).	perchlorate	90-94	albumin	Homo sapiens	147-160
1328820-5	1992	Comparing both experimental situations, perchlorate treatment significantly reduced intrathyroidal iodine concentration (4.0 +/- 1.3 to 3.0 +/- 1.2 nmol/mL, P less than .05), but thyroid volume and total serum T4, T3, FT3, and TBG levels were not altered.	perchlorate	40-51	serpin family A member 7	Homo sapiens	227-230
18965059-2	1990	Pb(II), present as the perchlorate, is precipitated by gentle boiling in 3.6M H(2)SO(4) presaturated with PbSO(4) and free from any extraneous anions.	perchlorate	23-34	submaxillary gland androgen regulated protein 3B	Homo sapiens	0-6
1646634-5	1991	(3) With the ATPase as H(+)-consuming pump, at equivalent delta mu H+ values, the output flow is more markedly inhibited by malonate than by uncouplers; the latter, however, are more inhibitory than lipophilic anions such as ClO4-.	perchlorate	225-229	dynein axonemal heavy chain 8	Homo sapiens	13-19
1316950-1	1992	The pH dependence of the apparent affinity constants of perchlorate for cobalt(II)bovine carbonic anhydrase II has been measured by electronic absorption spectroscopy.	perchlorate	56-67	carbonic anhydrase 2	Bos taurus	89-110
1972336-6	1990	Freezing in the presence of strong chaotropic anions (perchlorate, iodide and thiocyanate) caused the irreversible inactivation of the mosquito AChE.	perchlorate	54-65	acetylcholinesterase (Cartwright blood group)	Homo sapiens	144-148
34558591-3	2021	The reaction of PdX2 (X- = BF4-, ClO4-, PF6-, and CF3SO3- instead of NO3-) with L gives rise to a spiro species, PdL2, as the final product, and anion exchange of the spiro products, (PdL2)(X)2, with NO3- produces the tripalladium cage ((NO3)@Pd3L6).	perchlorate	33-37	NBL1, DAN family BMP antagonist	Homo sapiens	238-241
33761607-4	2021	Then we also found that [Mn(PaPy2Q)(NO)]ClO4 increased the expression of apoptosis-related proteins (PARP, Bax, Caspase 3/9), inhibited the expression of BCl-2 and increased the activity level of Caspase 3/7, which showed [Mn(PaPy2Q)(NO)]ClO4 promoted prostate cancer cells apoptosis.	perchlorate	40-44	BCL2 associated X, apoptosis regulator	Homo sapiens	107-110
33761607-4	2021	Then we also found that [Mn(PaPy2Q)(NO)]ClO4 increased the expression of apoptosis-related proteins (PARP, Bax, Caspase 3/9), inhibited the expression of BCl-2 and increased the activity level of Caspase 3/7, which showed [Mn(PaPy2Q)(NO)]ClO4 promoted prostate cancer cells apoptosis.	perchlorate	40-44	caspase 3	Homo sapiens	112-123
33761607-4	2021	Then we also found that [Mn(PaPy2Q)(NO)]ClO4 increased the expression of apoptosis-related proteins (PARP, Bax, Caspase 3/9), inhibited the expression of BCl-2 and increased the activity level of Caspase 3/7, which showed [Mn(PaPy2Q)(NO)]ClO4 promoted prostate cancer cells apoptosis.	perchlorate	40-44	BCL2 apoptosis regulator	Homo sapiens	154-159
33761607-4	2021	Then we also found that [Mn(PaPy2Q)(NO)]ClO4 increased the expression of apoptosis-related proteins (PARP, Bax, Caspase 3/9), inhibited the expression of BCl-2 and increased the activity level of Caspase 3/7, which showed [Mn(PaPy2Q)(NO)]ClO4 promoted prostate cancer cells apoptosis.	perchlorate	40-44	caspase 3	Homo sapiens	196-207
34218037-0	2021	Perchlorate in shellfish from South China Sea and implications for human exposure.	perchlorate	0-11	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	42-45
34554749-5	2021	Our results show that the charged amino acids (i.e., Arg and Lys) can strongly lock anions (ClO4-).	perchlorate	92-96	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	53-56
34218037-5	2021	This study aimed to investigate the abundances of perchlorate in shellfish from South China Sea and to assess human exposure risks.	perchlorate	50-61	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	92-95
35292321-3	2022	The Cyclic voltammetry (CV) capacitance increased from 487.5, 465.8 and 407.8 muF to 576.5, 552.4, 549.6 muF in C1, C3 and C5 compartments of ABR system, respectively, suggesting the electron transfer capacity was enhanced under high-strength perchlorate stress.	perchlorate	243-254	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	112-118
35583102-4	2022	The single-crystal X-ray structures of the representative mixed valent (1)ClO4 and (3)ClO4 established (i) Ru Ru distances of 6.227 A and 6.256 A (molecule A)/6.184 A (molecule B), respectively, (ii) a significant variation of the N-S distance of BTD in (3)ClO4 as a function of its binding mode mu versus eta1 and (iii) similar Ru-N (mu-BTD) distances in each case corresponding to a valence delocalised situation.	perchlorate	74-78	secreted phosphoprotein 1	Homo sapiens	306-310
35583102-4	2022	The single-crystal X-ray structures of the representative mixed valent (1)ClO4 and (3)ClO4 established (i) Ru Ru distances of 6.227 A and 6.256 A (molecule A)/6.184 A (molecule B), respectively, (ii) a significant variation of the N-S distance of BTD in (3)ClO4 as a function of its binding mode mu versus eta1 and (iii) similar Ru-N (mu-BTD) distances in each case corresponding to a valence delocalised situation.	perchlorate	86-90	secreted phosphoprotein 1	Homo sapiens	306-310
35608043-4	2022	Here, we have exploited this effect in the investigation of conformational differences in the molten globule states of cyt c induced by different sodium anions, namely sulfate, chloride and perchlorate.	perchlorate	190-201	cytochrome c, somatic	Homo sapiens	119-124
35360694-0	2022	Targeted Lipidomics Reveal the Effect of Perchlorate on Lipid Profiles in Liver of High-Fat Diet Mice.	perchlorate	41-52	histocompatibility 40	Mus musculus	83-87
35065174-0	2022	Enhanced bioremediation of RDX and Co-Contaminants perchlorate and nitrate using an anaerobic dehalogenating consortium in a fractured rock aquifer.	perchlorate	51-62	radixin	Homo sapiens	27-30
35065174-2	2022	Bioremediation of RDX is feasible through biostimulation of native microbes with an organic carbon donor but may be less efficient, or not occur at all, in the presence of the common co-contaminants perchlorate and nitrate.	perchlorate	199-210	radixin	Homo sapiens	18-21
35065174-7	2022	In microcosms with groundwater containing perchlorate and nitrate, RDX degradation began without delay when bioaugmented with 10% WBC-2.	perchlorate	42-53	radixin	Homo sapiens	67-70
35065174-11	2022	Single-well injection tests with WBC-2 and lactate showed that the onset of RDX degradation coincided with the onset of sulfide production, which was affected by the initial perchlorate concentration.	perchlorate	174-185	radixin	Homo sapiens	76-79
35385113-2	2022	Perchlorate is an environmental contaminant that interferes with iodine uptake into the thyroid gland to reduce TH synthesis.	perchlorate	0-11	tyrosine hydroxylase	Rattus norvegicus	112-114
35385113-3	2022	As TH are critical for brain development, exposure to perchlorate during pregnancy is of concern for the developing fetal brain.	perchlorate	54-65	tyrosine hydroxylase	Rattus norvegicus	3-5
35385113-4	2022	In this study we 1) define profiles of TH in the maternal and fetal compartments of pregnant rats in response to inhibition of the sodium-iodine symporter (NIS) by perchlorate, 2) expand inquiry previously limited to serum to include fetal thyroid gland and brain.	perchlorate	164-175	tyrosine hydroxylase	Rattus norvegicus	39-41
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	47-52	caveolin 1	Homo sapiens	21-26
35431660-6	2022	1X 2  sf are not isomorphous with the acetone solvates, and exhibit abrupt spin transitions at low temperature with hysteresis loops of 30-38 K (X- = BF4 -) and 10-20 K (X- = ClO4 -), depending on the measurement method.	perchlorate	175-179	spindlin 1	Homo sapiens	75-79
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	47-52	caveolin 1	Homo sapiens	38-43
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	47-52	caveolin 1	Homo sapiens	138-143
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	158-163	caveolin 1	Homo sapiens	21-26
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	158-163	caveolin 1	Homo sapiens	38-43
34964180-2	2022	The dinuclear ((CNC)(PPh 3 )Pd- G11 M(PPh 3 ))(ClO 4 ) ( G11 M = Au ( 3 ), Ag ( 4 ); CNC = 2,6-diphenylpyridinate) and trinuclear ({(CNC)(PPh 3 )Pd} 2 G11 M)(ClO 4 ) ( G11 M = Au ( 6 ), Ag ( 5 )) complexes have been accessed or isolated.	perchlorate	158-163	caveolin 1	Homo sapiens	138-143
18964727-0	1989	Ion-pair extraction of Co(II) by crown ethers from perchlorate medium.	perchlorate	51-62	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	23-28
2557729-0	1989	Perchlorate stimulates potassium-induced growth hormone release in cultured rat somatotrophs.	perchlorate	0-11	gonadotropin releasing hormone receptor	Rattus norvegicus	41-55
2418616-9	1985	Corresponding mean values for the discharge rate constant after perchlorate were 0.087 to 0.105 min-1.	perchlorate	64-75	CD59 molecule (CD59 blood group)	Homo sapiens	96-101
18964420-0	1987	Hydroxide complexes of lanthanides-VIII Lanthanum(III) in perchlorate medium.	perchlorate	58-69	cytochrome c oxidase subunit 8A	Homo sapiens	35-39
18963471-5	1983	This phenomenon is interpreted by postulating ion-pair formation between perchlorate and the protonated form of bipyridyl, HBp(+) + ClO(4)(-) rlharr2; HBp(+).ClO(4)(-) with formation constants of 0.54 in 2M lithium nitrate and 0.45 in 2M sodium nitrate.	perchlorate	73-84	heme binding protein 1	Homo sapiens	123-126
6096645-0	1984	Effect of perchlorate treatment on mitochondrial MAO-A and -B activities.	perchlorate	10-21	monoamine oxidase A	Rattus norvegicus	49-61
6096645-3	1984	Of those activities, virtually no (2%) MAO-A activity, but appreciable (28%) MAO-B activity survived in the soluble state after the subsequent perchlorate treatment.	perchlorate	143-154	monoamine oxidase B	Rattus norvegicus	77-82
18963471-5	1983	This phenomenon is interpreted by postulating ion-pair formation between perchlorate and the protonated form of bipyridyl, HBp(+) + ClO(4)(-) rlharr2; HBp(+).ClO(4)(-) with formation constants of 0.54 in 2M lithium nitrate and 0.45 in 2M sodium nitrate.	perchlorate	73-84	heme binding protein 1	Homo sapiens	151-154