PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32816304-8 2021 The results of this study indicated that TNF-alpha inhibits SHOX2 expression and has promoted effects on IVDD in the rat model, and this effects might be associated with through NF-kappaB signaling pathway and promotes IVDD and related pain in a rat model. ivdd 105-109 tumor necrosis factor Rattus norvegicus 41-50 32816304-8 2021 The results of this study indicated that TNF-alpha inhibits SHOX2 expression and has promoted effects on IVDD in the rat model, and this effects might be associated with through NF-kappaB signaling pathway and promotes IVDD and related pain in a rat model. ivdd 219-223 tumor necrosis factor Rattus norvegicus 41-50 10330471-0 1999 CHL1 is a dual-affinity nitrate transporter of Arabidopsis involved in multiple phases of nitrate uptake. Nitrates 24-31 nitrate transporter 1.1 Arabidopsis thaliana 0-4 10367389-4 1999 The peak interfering with BCAA elutes at the same retention time as nitrate; however, we have not confirmed the presence of nitrate. Nitrates 68-75 AT-rich interaction domain 4B Homo sapiens 26-30 10235127-6 1999 This deteriorative action of postadministration of L-arginine (300 mg/kg intraperitoneally) was prevented by pretreatment with aminoguanidine (100 mg/kg subcutaneously), a selective iNOS inhibitor, with inhibition of increases in gastric mucosal iNOS activity and nitrite/nitrate concentration. Nitrates 272-279 nitric oxide synthase 2 Rattus norvegicus 182-186 10330471-3 1999 Here, we demonstrate that a well-known low-affinity nitrate uptake mutant of Arabidopsis, chl1, is also defective in high-affinity nitrate uptake. Nitrates 52-59 nitrate transporter 1.1 Arabidopsis thaliana 90-94 10330471-3 1999 Here, we demonstrate that a well-known low-affinity nitrate uptake mutant of Arabidopsis, chl1, is also defective in high-affinity nitrate uptake. Nitrates 131-138 nitrate transporter 1.1 Arabidopsis thaliana 90-94 10350003-0 1999 The nitric oxide donor SIN-1 is free of tolerance and maintains its cyclic GMP stimulatory potency in nitrate-tolerant LLC-PK1 cells. Nitrates 102-109 MAPK associated protein 1 Homo sapiens 23-28 10330471-4 1999 Two to 3 hr after nitrate induction, uptake activities of various chl1 mutants at 250 microM nitrate (a high-affinity concentration) were only 18 to 30% of those of wild-type plants. Nitrates 18-25 nitrate transporter 1.1 Arabidopsis thaliana 66-70 10330471-4 1999 Two to 3 hr after nitrate induction, uptake activities of various chl1 mutants at 250 microM nitrate (a high-affinity concentration) were only 18 to 30% of those of wild-type plants. Nitrates 93-100 nitrate transporter 1.1 Arabidopsis thaliana 66-70 10330471-7 1999 Kinetic analysis of nitrate uptake by CHL1-injected Xenopus oocytes displayed a biphasic pattern with a Michaelis-Menten Km value of approximately 50 microM for the high-affinity phase and approximately 4 mM for the low-affinity phase. Nitrates 20-27 DEAD/H-box helicase 11 L homeolog Xenopus laevis 38-42 10330471-8 1999 These results indicate that in addition to being a low-affinity nitrate transporter, as previously recognized, CHL1 is also involved in both the inducible and constitutive phases of high-affinity nitrate uptake in Arabidopsis. Nitrates 64-71 nitrate transporter 1.1 Arabidopsis thaliana 111-115 10190728-4 1999 RESULTS: vWF:antigen and nitrite/nitrate levels were significantly higher in cirrhotic patients (367+/-185% and 29.3+/-10.8 micromol/l) than in healthy subjects (92+/-20% and 19.2+/-8.3 micromol/l, p<0.05, respectively). Nitrates 33-40 von Willebrand factor Homo sapiens 9-12 10208844-6 1999 Treatment of rats with the selective iNOS inhibitor L-iminoethyl-lysine (L-NIL) dramatically reduced NO levels in lavage fluid as measured by decreases in nitrate and nitrite concentrations without significantly affecting iNOS protein levels. Nitrates 155-162 nitric oxide synthase 2 Rattus norvegicus 37-41 10037703-3 1999 By using high performance anion-exchange chromatography (HPAEC) with nitrate eluents, we found that lactonization of alpha2,8-linked OSA/PSA (oligo/poly-Neu5Ac, oligo/poly-Neu5Gc and oligo/poly-KDN) proceeds readily, and the lactonization process displays three discrete stages. Nitrates 69-76 aminopeptidase puromycin sensitive Homo sapiens 137-140 10190728-7 1999 In the overall series, a highly significant linear correlation between nitrites/nitrates and vWF:antigen levels was observed in patients with cirrhosis (r=0.79, p<0.001). Nitrates 80-88 von Willebrand factor Homo sapiens 93-96 28307406-4 1999 We used this method to examine spatial patterns of soil ammonium (NH+4) and nitrate (NO-3) availability in a mid-successional coastal dune for four periods of time during the growing season. Nitrates 76-83 NBL1, DAN family BMP antagonist Homo sapiens 85-89 10205909-1 1999 Putative high-affinity nitrate (NO3-) transporter genes, designated Nrt2;1At and Nrt2;2At, were isolated from Arabidopsis thaliana by RT-PCR using degenerate primers. Nitrates 23-30 nitrate transporter 2:1 Arabidopsis thaliana 68-72 10205909-1 1999 Putative high-affinity nitrate (NO3-) transporter genes, designated Nrt2;1At and Nrt2;2At, were isolated from Arabidopsis thaliana by RT-PCR using degenerate primers. Nitrates 23-30 nitrate transporter 2:1 Arabidopsis thaliana 81-85 10203321-1 1999 To elucidate the involvement of NO in pain transmission in humans, we measured NO metabolites (nitrite/nitrate) in the CSF of patients with painful diseases using an NO analyzer based on the Griess method. Nitrates 103-110 colony stimulating factor 2 Homo sapiens 119-122 10205669-0 1999 Roles of nitrate, nitrite and ammonium ion in phytochrome regulation of nitrate reductase gene expression in maize. Nitrates 9-16 nitrate reductase [NADH] 1 Zea mays 72-89 10205669-1 1999 The influence of nitrate and its metabolites on the nitrate reductase (NR) gene expression and its relationship with phytochrome (Pfr) regulation of NR in etiolated maize leaves is examined. Nitrates 17-24 nitrate reductase [NADH] 1 Zea mays 52-69 10205669-1 1999 The influence of nitrate and its metabolites on the nitrate reductase (NR) gene expression and its relationship with phytochrome (Pfr) regulation of NR in etiolated maize leaves is examined. Nitrates 17-24 nitrate reductase [NADH] 1 Zea mays 71-73 10205669-6 1999 The products of nitrate reduction i.e., nitrite and ammonium ion had inhibitory and stimulatory effects respectively, on NR transcript accumulation. Nitrates 16-23 nitrate reductase [NADH] 1 Zea mays 121-123 10063925-6 1999 Adrenomedullin levels had significant correlations with aldosterone (r = 0.55; P < 0.001), plasma renin activity (r = 0.49; P < 0.001) and nitrates-nitrites levels (r = 0.52; P < 0.001). Nitrates 145-153 adrenomedullin Homo sapiens 0-14 9845803-0 1999 Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers. Nitrates 57-64 trefoil factor 3 Homo sapiens 20-23 9845803-1 1999 ITF 296 is a new orally active nitrate acting selectively on large arterial vessels over a wide range of doses. Nitrates 31-38 trefoil factor 3 Homo sapiens 0-3 10190728-5 1999 Higher levels of vWF:antigen and nitrites/nitrates were observed in patients with more advanced degrees of liver failure, as reflected by quantitative Child-Pugh"s score (516+/-154% and 38.3+/-7.8 micromol/l in Child-Pugh > or = 9 vs 227+/-61% and 21.0+/-6.1 micromol/l in Child-Pugh <9, p<0.001, respectively). Nitrates 42-50 von Willebrand factor Homo sapiens 17-20 9854041-8 1998 Thus, our novel mouse model of chronic eNOS overexpression demonstrates that, in addition to the essential role of eNOS in blood pressure regulation, tonic NO release by eNOS in the endothelium induces the reduced vascular reactivity to NO-mediated vasodilators, providing several insights into the pathogenesis of nitrate tolerance. Nitrates 315-322 nitric oxide synthase 3, endothelial cell Mus musculus 39-43 10362348-5 1999 Recent studies have shown that the use of nitrates in patients already treated with standard heart failure therapy, including angiotensin converting enzyme (ACE) inhibitors, resulted in hemodynamic improvement, marked enhancement of exercise tolerance, reduction of left ventricular size, and augmentation of systolic function. Nitrates 42-50 angiotensin I converting enzyme Homo sapiens 126-155 10362348-5 1999 Recent studies have shown that the use of nitrates in patients already treated with standard heart failure therapy, including angiotensin converting enzyme (ACE) inhibitors, resulted in hemodynamic improvement, marked enhancement of exercise tolerance, reduction of left ventricular size, and augmentation of systolic function. Nitrates 42-50 angiotensin I converting enzyme Homo sapiens 157-160 9844028-0 1998 The Arabidopsis CHL1 protein plays a major role in high-affinity nitrate uptake. Nitrates 65-72 nitrate transporter 1.1 Arabidopsis thaliana 16-20 9844028-1 1998 The CHL1 (NRT1) gene of Arabidopsis encodes a nitrate-inducible nitrate transporter that is thought to be a component of the low-affinity (mechanism II) nitrate-uptake system in plants. Nitrates 46-53 nitrate transporter 1.1 Arabidopsis thaliana 4-8 9844028-1 1998 The CHL1 (NRT1) gene of Arabidopsis encodes a nitrate-inducible nitrate transporter that is thought to be a component of the low-affinity (mechanism II) nitrate-uptake system in plants. Nitrates 46-53 nitrate transporter 1.1 Arabidopsis thaliana 10-14 9844028-1 1998 The CHL1 (NRT1) gene of Arabidopsis encodes a nitrate-inducible nitrate transporter that is thought to be a component of the low-affinity (mechanism II) nitrate-uptake system in plants. Nitrates 64-71 nitrate transporter 1.1 Arabidopsis thaliana 4-8 9844028-1 1998 The CHL1 (NRT1) gene of Arabidopsis encodes a nitrate-inducible nitrate transporter that is thought to be a component of the low-affinity (mechanism II) nitrate-uptake system in plants. Nitrates 64-71 nitrate transporter 1.1 Arabidopsis thaliana 10-14 9844028-8 1998 These results show that CHL1 is an important component of both the high-affinity and the low-affinity nitrate-uptake systems and indicate that CHL1 may be a dual-affinity nitrate transporter. Nitrates 102-109 nitrate transporter 1.1 Arabidopsis thaliana 143-147 9844028-6 1998 chl1 mutants show reduced membrane depolarization in root epidermal cells in response to low (250 microM) and high (10 mM) concentrations of nitrate. Nitrates 141-148 nitrate transporter 1.1 Arabidopsis thaliana 0-4 9844028-7 1998 Low levels of nitrate (100 microM) induce a rapid increase in CHL1 mRNA. Nitrates 14-21 nitrate transporter 1.1 Arabidopsis thaliana 62-66 9853182-0 1998 The impact of beta-receptor blocker addition to high-dose angiotensin-converting enzyme inhibitor-nitrate therapy in heart failure. Nitrates 98-105 angiotensin I converting enzyme Homo sapiens 58-87 9843849-2 1998 NO can combine with superoxide (O-2) to form peroxynitrite, which can decompose into nitrate. Nitrates 85-92 immunoglobulin kappa variable 1D-39 Homo sapiens 32-35 9843849-10 1998 These data demonstrate that O-2 released from PMNs can decrease NO by conversion to nitrate and suggest a potential mechanism for modulation of NO levels in vivo. Nitrates 84-91 immunoglobulin kappa variable 1D-39 Homo sapiens 28-31 9853182-3 1998 Similarly, high doses of angiotensin-converting enzyme (ACE) inhibitors with nitrates partially reverse the ventricular remodeling of heart failure. Nitrates 77-85 angiotensin I converting enzyme Homo sapiens 25-54 9853182-3 1998 Similarly, high doses of angiotensin-converting enzyme (ACE) inhibitors with nitrates partially reverse the ventricular remodeling of heart failure. Nitrates 77-85 angiotensin I converting enzyme Homo sapiens 56-59 9853182-4 1998 HYPOTHESIS: We tested the hypothesis that beta-blocker therapy added to high-dose ACE inhibitor-nitrates would potentiate the reversal of heart failure. Nitrates 96-104 angiotensin I converting enzyme Homo sapiens 82-85 9853182-13 1998 CONCLUSION: High-dose ACE inhibitor-nitrate therapy significantly improved patient clinical status and left ventricular systolic function in heart failure. Nitrates 36-43 angiotensin I converting enzyme Homo sapiens 22-25 9794807-0 1998 Clustering of the YNA1 gene encoding a Zn(II)2Cys6 transcriptional factor in the yeast Hansenula polymorpha with the nitrate assimilation genes YNT1, YNI1 and YNR1, and its involvement in their transcriptional activation. Nitrates 117-124 rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C 18-22 9794807-0 1998 Clustering of the YNA1 gene encoding a Zn(II)2Cys6 transcriptional factor in the yeast Hansenula polymorpha with the nitrate assimilation genes YNT1, YNI1 and YNR1, and its involvement in their transcriptional activation. Nitrates 117-124 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 144-148 9794807-2 1998 In addition, DNA sequencing of the region containing these genes demonstrated that a new open reading frame called YNA1 (yeast nitrate assimilation) was located between YNR1 and YNI1. Nitrates 127-134 rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C 115-119 9794807-3 1998 The YNA1 gene encodes a protein of 529 residues belonging to the family of Zn(II)2Cys6 fungal transcriptional factors, and has the highest similarity to the transcriptional factors encoded by nirA, and to a smaller extent to nit-4, involved in the nitrate induction of the gene involved in the assimilation of this compound in filamentous fungi. Nitrates 248-255 rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C 4-8 9794807-4 1998 Northern blot analysis showed the presence of the YNA1 transcript in cells incubated in nitrate, nitrate plus ammonium, ammonium, and nitrogen-free media, with a decrease in its levels in those cells incubated in ammonium. Nitrates 88-95 rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C 50-54 9794807-4 1998 Northern blot analysis showed the presence of the YNA1 transcript in cells incubated in nitrate, nitrate plus ammonium, ammonium, and nitrogen-free media, with a decrease in its levels in those cells incubated in ammonium. Nitrates 97-104 rRNA (cytosine-C5-)-methyltransferase NOP2 Saccharomyces cerevisiae S288C 50-54 9881153-9 1998 Expression studies at the protein and mRNA levels show that each subunit is present in both root and leaf tissues and that the three IDH genes respond in the same way to nitrate addition. Nitrates 170-177 isocitrate dehydrogenase [NADP] Nicotiana tabacum 133-136 9821686-11 1998 The negative effect on the nia2 transcript pool exerted by exogeneous glutamine may, therefore, be explained as a result of the down-regulation of nitrate-uptake permeases in the roots by glutamine. Nitrates 147-154 nitrate reductase 2 Arabidopsis thaliana 27-31 9767541-6 1998 Kallikrein gene transfer caused left ventricular mass reduction and elevated glomerular filtration rate, renal blood flow, urinary excretion, urinary kinin, nitrite/nitrate content, cGMP and cAMP levels. Nitrates 165-172 kallikrein related peptidase 4 Homo sapiens 0-10 9763537-7 1998 045), hypertriglyceridemia (P=0.015), and chronic intake of nitrates (P<0.001) were significantly and positively related to tPA antigen concentration, while the chronic intake of aspirin was inversely related to tPA antigen (P<0.001). Nitrates 60-68 plasminogen activator, tissue type Homo sapiens 127-130 9811394-9 1998 There are a few studies assessing NO generation in hypertensive children via plasma nitrite and nitrate, the NO end products, which suggest normal or increased production as opposed to a reduction, perhaps as a compensatory phenomenon. Nitrates 96-103 nitric oxide synthase 2 Homo sapiens 34-36 9811394-10 1998 In the treatment of hypertension, nitroprusside and nitrates exert their actions via NO donation. Nitrates 52-60 nitric oxide synthase 2 Homo sapiens 85-87 9788654-10 1998 Nitrate+nitrite levels returned to normal within 24 h. CRP generation increased during 12 h following trauma and was most marked in severest trauma (ISS >50). Nitrates 0-7 C-reactive protein Homo sapiens 55-58 9737004-0 1998 Clustering of the nitrite reductase gene and a light-regulated gene with nitrate assimilation loci in Chlamydomonas reinhardtii. Nitrates 73-80 uncharacterized protein Chlamydomonas reinhardtii 18-35 9662428-1 1998 We examined cytokinin and nitrate responsiveness in gene expression of five distinct response regulator homologs (ARR3-ARR7) in the leaves of nitrogen-starved Arabidopsis plants. Nitrates 26-33 response regulator 3 Arabidopsis thaliana 114-118 9759915-3 1998 In this study, the effect of activation P2Z/P2X7 receptor was investigated on the bacterial lipopolysaccharide induced nitric oxide production in RAW 264.7 macrophage call line using the nitrite/nitrate assay. Nitrates 195-202 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 44-57 9715532-6 1998 Induction of GmNRT2 mRNA levels in roots occurred within 1 h after exposure of plants to nitrate. Nitrates 89-96 NRT2 protein Glycine max 13-19 9715532-7 1998 Nitrate induction of GmNRT2 mRNA levels was accompanied by a fourfold increase in net nitrate uptake by soybean roots at 100 microM external nitrate. Nitrates 0-7 NRT2 protein Glycine max 21-27 9715532-7 1998 Nitrate induction of GmNRT2 mRNA levels was accompanied by a fourfold increase in net nitrate uptake by soybean roots at 100 microM external nitrate. Nitrates 86-93 NRT2 protein Glycine max 21-27 9715532-7 1998 Nitrate induction of GmNRT2 mRNA levels was accompanied by a fourfold increase in net nitrate uptake by soybean roots at 100 microM external nitrate. Nitrates 141-148 NRT2 protein Glycine max 21-27 9715532-8 1998 The molecular and physiological evidence indicates that GmNRT2 is probably a high-affinity nitrate transporter involved in nitrate uptake by soybean roots. Nitrates 91-98 NRT2 protein Glycine max 56-62 9759949-8 1998 RESULTS: In all of seven specimens from children with increased levels of nitrate/nitrite in the urine, we detected antibodies to iNOS, whereas in five of six control specimens--that is, from children with normal nitrate/nitrite levels--we could not detect any iNOS. Nitrates 74-81 nitric oxide synthase 2 Homo sapiens 130-134 9844028-8 1998 These results show that CHL1 is an important component of both the high-affinity and the low-affinity nitrate-uptake systems and indicate that CHL1 may be a dual-affinity nitrate transporter. Nitrates 102-109 nitrate transporter 1.1 Arabidopsis thaliana 24-28 9698594-9 1998 Both types of asbestos fibers also induced iNOS protein expression and the formation of nitrotyrosine in mesothelial cells and greatly induced the formation of nitrate (NO3-), a surrogate marker of ONOO- formation, in IL-1beta-stimulated cells. Nitrates 160-167 interleukin 1 beta Rattus norvegicus 218-226 9865496-5 1998 Our present data show a correlation between the production of nitrite + nitrate (NO2- + NO3-) and that of circulating cytokines IFN and IL-6. Nitrates 72-79 NBL1, DAN family BMP antagonist Homo sapiens 88-91 9865496-5 1998 Our present data show a correlation between the production of nitrite + nitrate (NO2- + NO3-) and that of circulating cytokines IFN and IL-6. Nitrates 72-79 interferon alpha 1 Homo sapiens 128-131 9865496-5 1998 Our present data show a correlation between the production of nitrite + nitrate (NO2- + NO3-) and that of circulating cytokines IFN and IL-6. Nitrates 72-79 interleukin 6 Homo sapiens 136-140 9675176-3 1998 Activated macrophages synthesize NO, which is oxidized in the culture medium by molecular oxygen and superoxide (O2-, also released by the cells), yielding mainly nitrite (NO2-) and nitrate (NO3-) as the respective end products. Nitrates 182-189 NBL1, DAN family BMP antagonist Homo sapiens 191-194 9716178-3 1998 In response to cytokine stimulation (tumor necrosis factor alpha, IFN-gamma, and interleukin 1beta), human pancreatic carcinoma cell lines expressed the inducible NO synthase that synthesizes NO, detectable as nitrate and nitrite in the culture supernatants. Nitrates 210-217 tumor necrosis factor Homo sapiens 37-64 9716178-3 1998 In response to cytokine stimulation (tumor necrosis factor alpha, IFN-gamma, and interleukin 1beta), human pancreatic carcinoma cell lines expressed the inducible NO synthase that synthesizes NO, detectable as nitrate and nitrite in the culture supernatants. Nitrates 210-217 interferon gamma Homo sapiens 66-75 9716178-3 1998 In response to cytokine stimulation (tumor necrosis factor alpha, IFN-gamma, and interleukin 1beta), human pancreatic carcinoma cell lines expressed the inducible NO synthase that synthesizes NO, detectable as nitrate and nitrite in the culture supernatants. Nitrates 210-217 interleukin 1 beta Homo sapiens 81-98 9708463-1 1998 OBJECTIVES: We sought to assess whether oxidation products of nitric oxide (NO), nitrite (NO2-) and nitrate (NO3-), referred to as NOx, are released by the heart of patients after acute myocardial infarction (AMI) and whether NOx can be determined in peripheral blood of these patients. Nitrates 100-107 NBL1, DAN family BMP antagonist Homo sapiens 109-112 9688317-4 1998 Following immunisation with myelin basic protein (MBP)-complete Freund"s adjuvant (CFA), PVG rats developed higher serum levels of the surrogate markers of nitric oxide production, reactive nitrogen intermediates (RNI; nitrite and nitrate), than did their Lewis counterparts. Nitrates 231-238 myelin basic protein Rattus norvegicus 28-48 9688317-4 1998 Following immunisation with myelin basic protein (MBP)-complete Freund"s adjuvant (CFA), PVG rats developed higher serum levels of the surrogate markers of nitric oxide production, reactive nitrogen intermediates (RNI; nitrite and nitrate), than did their Lewis counterparts. Nitrates 231-238 myelin basic protein Rattus norvegicus 50-53 9691115-4 1998 Maximal second order binding rates between 40,000 and 80,000 (m-1 x sec-1) were obtained for chlorides and nitrates of 1a group alkali ions with the exception of lithium supporting only rates of maximally 10,000 (M-1 x sec-1). Nitrates 107-115 myoregulin Homo sapiens 62-65 9691115-4 1998 Maximal second order binding rates between 40,000 and 80,000 (m-1 x sec-1) were obtained for chlorides and nitrates of 1a group alkali ions with the exception of lithium supporting only rates of maximally 10,000 (M-1 x sec-1). Nitrates 107-115 secretory blood group 1, pseudogene Homo sapiens 68-73 9673545-5 1998 We examined mRNA expression of inducible NO synthase (iNOS) in circulating PMNs from those patients pre- and postoperatively using the reverse transcriptase polymerase chain reaction (RT-PCR) method and measured their serum nitrate (NO2-) + nitrate (NO3-) concentration, peripheral blood white cell (WBC) count, and serum C-reactive protein (CRP) level. Nitrates 241-248 nitric oxide synthase 2 Homo sapiens 31-52 9673545-5 1998 We examined mRNA expression of inducible NO synthase (iNOS) in circulating PMNs from those patients pre- and postoperatively using the reverse transcriptase polymerase chain reaction (RT-PCR) method and measured their serum nitrate (NO2-) + nitrate (NO3-) concentration, peripheral blood white cell (WBC) count, and serum C-reactive protein (CRP) level. Nitrates 241-248 nitric oxide synthase 2 Homo sapiens 54-58 9668089-10 1998 5-CHO-THF influx was restored by addition of chloride, fluoride, or nitrate but not by sulfate, phosphate, or ATP which were all inhibitory over a broad range of concentrations. Nitrates 68-75 thin fur Mus musculus 6-9 9671763-5 1998 We report here that untreated p53 KO mice excreted 70% more nitrite plus nitrate than mice with wild-type (wt) p53. Nitrates 73-80 transformation related protein 53, pseudogene Mus musculus 30-33 9671763-7 1998 Upon treatment with heat-inactivated Corynebacterium parvum, urinary nitrite plus nitrate excretion of p53 KO mice exceeded that of wt controls by approximately 200%. Nitrates 82-89 transformation related protein 53, pseudogene Mus musculus 103-106 9655731-2 1998 It is produced by nitric oxide synthase (NOS) and is rapidly metabolized to nitrite and nitrate (NO2/NO3). Nitrates 88-95 nitric oxide synthase 2 Homo sapiens 18-39 9655731-2 1998 It is produced by nitric oxide synthase (NOS) and is rapidly metabolized to nitrite and nitrate (NO2/NO3). Nitrates 88-95 NBL1, DAN family BMP antagonist Homo sapiens 101-104 9639597-0 1998 Functional citric acid cycle in an arcA mutant of Escherichia coli during growth with nitrate under anoxic conditions. Nitrates 86-93 arginine deiminase Escherichia coli 35-39 9639597-4 1998 In an arcA mutant devoid of the transcriptional regulator ArcA, glycerol was completely oxidized with nitrate as an electron acceptor, demonstrating derepression and function of the complete pathway. Nitrates 102-109 arginine deiminase Escherichia coli 6-10 9639597-4 1998 In an arcA mutant devoid of the transcriptional regulator ArcA, glycerol was completely oxidized with nitrate as an electron acceptor, demonstrating derepression and function of the complete pathway. Nitrates 102-109 arginine deiminase Escherichia coli 58-62 9694586-5 1998 This procedure, supplemented with deproteinization and reduction of nitrates to nitrites in the presence of NADPH-sensitive reductase, can be successfully applied for measurement of NOx levels in human body fluids (serum, urine and CSF). Nitrates 68-76 colony stimulating factor 2 Homo sapiens 232-235 9662428-1 1998 We examined cytokinin and nitrate responsiveness in gene expression of five distinct response regulator homologs (ARR3-ARR7) in the leaves of nitrogen-starved Arabidopsis plants. Nitrates 26-33 response regulator 7 Arabidopsis thaliana 119-123 9631803-10 1998 IL-10 levels correlated with IL-6 levels (days 1 and 2) and nitrite+nitrate levels (days 1 and 3; p<0.05). Nitrates 68-75 interleukin 10 Homo sapiens 0-5 9625727-3 1998 Regression analysis of serum ALT levels to serum nitrate plus nitrite levels in individual mice revealed a positive, linear relationship between serum ALT levels and serum nitrate plus nitrite levels with a correlation coefficient of 0.9 (P < 0.05). Nitrates 49-56 glutamic pyruvic transaminase, soluble Mus musculus 29-32 9625727-3 1998 Regression analysis of serum ALT levels to serum nitrate plus nitrite levels in individual mice revealed a positive, linear relationship between serum ALT levels and serum nitrate plus nitrite levels with a correlation coefficient of 0.9 (P < 0.05). Nitrates 49-56 glutamic pyruvic transaminase, soluble Mus musculus 151-154 9625727-3 1998 Regression analysis of serum ALT levels to serum nitrate plus nitrite levels in individual mice revealed a positive, linear relationship between serum ALT levels and serum nitrate plus nitrite levels with a correlation coefficient of 0.9 (P < 0.05). Nitrates 172-179 glutamic pyruvic transaminase, soluble Mus musculus 29-32 9625727-3 1998 Regression analysis of serum ALT levels to serum nitrate plus nitrite levels in individual mice revealed a positive, linear relationship between serum ALT levels and serum nitrate plus nitrite levels with a correlation coefficient of 0.9 (P < 0.05). Nitrates 172-179 glutamic pyruvic transaminase, soluble Mus musculus 151-154 9607316-0 1998 Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. Nitrates 51-59 xanthine dehydrogenase Homo sapiens 0-23 9607316-1 1998 Xanthine oxidoreductase (XOR) catalyses the reduction of the therapeutic organic nitrate, nitroglycerin (glyceryl trinitrate, GTN), as well as inorganic nitrate and nitrite, to nitric oxide (NO) under hypoxic conditions in the presence of NADH. Nitrates 81-88 xanthine dehydrogenase Homo sapiens 0-23 9607316-1 1998 Xanthine oxidoreductase (XOR) catalyses the reduction of the therapeutic organic nitrate, nitroglycerin (glyceryl trinitrate, GTN), as well as inorganic nitrate and nitrite, to nitric oxide (NO) under hypoxic conditions in the presence of NADH. Nitrates 81-88 xanthine dehydrogenase Homo sapiens 25-28 9607316-1 1998 Xanthine oxidoreductase (XOR) catalyses the reduction of the therapeutic organic nitrate, nitroglycerin (glyceryl trinitrate, GTN), as well as inorganic nitrate and nitrite, to nitric oxide (NO) under hypoxic conditions in the presence of NADH. Nitrates 117-124 xanthine dehydrogenase Homo sapiens 0-23 9607316-1 1998 Xanthine oxidoreductase (XOR) catalyses the reduction of the therapeutic organic nitrate, nitroglycerin (glyceryl trinitrate, GTN), as well as inorganic nitrate and nitrite, to nitric oxide (NO) under hypoxic conditions in the presence of NADH. Nitrates 117-124 xanthine dehydrogenase Homo sapiens 25-28 9573546-7 1998 Kallikrein gene delivery caused a decrease in blood urea nitrogen levels and increases in urinary kinin and nitrite/nitrate levels. Nitrates 116-123 kallikrein related peptidase 4 Homo sapiens 0-10 9626580-5 1998 This Lb-NO species, which has not been previously detected in intact root nodules of plants grown in the absence of nitrate, is thought to be formed by reaction of nitric oxide with iron(II) leghemoglobin. Nitrates 116-123 leghemoglobin A Glycine max 5-7 9628026-6 1998 In whole plants, ZmCip1 transcript was transiently accumulated exclusively in leaves by supply of nitrate or ammonium ions to the roots, whereas the transcript was not accumulated in detached leaves by supply of the nitrogen nutrients. Nitrates 98-105 cytokinin response regulator 1 Zea mays 17-23 9648741-1 1998 Two new nitrate assimilation-related genes, Nrt2;3 and Nar5, have been identified in Chlamydomonas reinhardtii. Nitrates 8-15 uncharacterized protein Chlamydomonas reinhardtii 55-59 9648741-3 1998 Like that of the nitrate assimilation genes, expression of the Nrt2;3 gene is down-regulated by ammonium and positively controlled by Nit2, a regulatory locus specific for the pathway. Nitrates 17-24 uncharacterized protein Chlamydomonas reinhardtii 134-138 9648741-8 1998 The Nrt2;3 and Nar5 genes are overexpressed in a deletion mutant that lacks nitrate assimilation loci. Nitrates 76-83 uncharacterized protein Chlamydomonas reinhardtii 15-19 9628026-7 1998 Both the cytokinin- and nitrate-responsive accumulations of ZmCip1 transcript were accompanied by an increase in the immunotitratable protein. Nitrates 24-31 cytokinin response regulator 1 Zea mays 60-66 9617881-2 1998 Here we report for the first time that 1400W, a novel and highly selective inhibitor of iNOS activity, attenuates the delayed hypotension as well as the rise in the plasma levels of nitrite/nitrate caused by endotoxin in the rat. Nitrates 190-197 nitric oxide synthase 2 Rattus norvegicus 88-92 9667074-3 1998 A good positive correlation between either serum or gastric mucosal nitrite/nitrate concentration and gastric mucosal iNOS activity in all rats used (r = 0.741 or 0.842, respectively, p < 0.001) was found. Nitrates 76-83 nitric oxide synthase 2 Rattus norvegicus 118-122 9617881-4 1998 Similarly, administration of another selective inhibitor of iNOS activity, L-NIL, 2 h after endotoxin injection abolished the rise in nitrite/nitrate and attenuated the delayed hypotension caused by endotoxin, but failed to ameliorate organ injury. Nitrates 142-149 nitric oxide synthase 2 Rattus norvegicus 60-64 9661284-4 1998 Cd2+ (20 microM) stimulated an extensive swelling of nonenergized mitochondria incubated in 125 mM nitrate media, the effect being increased in the series of Li < Na < K < NH4. Nitrates 99-106 Cd2 molecule Rattus norvegicus 0-3 9523847-9 1998 A significant decrease in nitrate from preoperative levels in groups A (postoperative day (POD) 1 and 3; p < 0.0005) and B (POD 1, p < 0.0001) was observed; nitrate levels in group C did not decrease for 14 days after surgery. Nitrates 26-33 coronin 7 Homo sapiens 72-103 9337353-0 1997 Nitrate plasma level as a marker of nitric oxide production after subcutaneous interleukin 2 immunotherapy. Nitrates 0-7 interleukin 2 Homo sapiens 79-92 9495884-4 1998 Induction of iNOS protein is inferred because urinary nitrate and cGMP levels are increased 4 hr after LPS intravesical instillation and remain elevated for at least 24 hr. Nitrates 54-61 nitric oxide synthase 2 Rattus norvegicus 13-17 9475262-6 1998 Increases in renin activity amounted to 130% (p < 0.001), 117% (p < 0.001), and 112% (p < 0.001) with molsidomine, and to 14, 16%, and 0 (each NS) with the nitrate at the corresponding times. Nitrates 165-172 renin Homo sapiens 13-18 9466545-2 1998 Doxycycline (at 1.5 mg/kg) exerted its protective effect by inhibiting nitrate production by an interleukin-10-independent mechanism. Nitrates 71-78 interleukin 10 Mus musculus 96-110 9514534-9 1998 Endotoxin and interleukin-6 levels increased in a similar manner to nitrate levels, but tumor necrosis factor-alpha and interleukin-1 beta levels did not. Nitrates 68-75 interleukin 6 Homo sapiens 14-27 9532589-5 1998 Nitrate and nitrite, were raised in the CSF and serum of patients with multiple sclerosis and other inflammatory neurological diseases compared to patients with non-inflammatory neurological disorders (median nitrate and nitrite: cerebrospinal fluid = 10.3 microM vs 15.4 microM vs 6.6 microM, P < 0.001, and serum = 49.0 microM vs 46.4 microM vs 38.8 microM, P = 0.02, respectively). Nitrates 0-7 colony stimulating factor 2 Homo sapiens 40-43 9532589-6 1998 CSF nitrate and nitrite levels correlated with the albumin quotient (n = 59, r = 0.42, P < 0.001). Nitrates 4-11 colony stimulating factor 2 Homo sapiens 0-3 9526673-2 1998 The levels of nitrite (NO2-) and nitrate (NO3-) were measured simultaneously by high-performance liquid chromatography (HPLC) with UV detection using the Griess reaction after the reduction of nitrate to nitrite. Nitrates 33-40 NBL1, DAN family BMP antagonist Homo sapiens 42-45 9458730-4 1998 NO production, measured by the accumulation of nitrite and nitrate, was enhanced by 10(-7) M ANG II. Nitrates 59-66 angiotensinogen Rattus norvegicus 93-99 9326589-4 1997 CooA is a member of a family of transcriptional regulators similar to the cAMP receptor protein and fumavate nitrate reduction from Escherichia coli. Nitrates 109-116 CS1 fimbrial subunit A precursor Escherichia coli 0-4 9626903-0 1998 Preventive effects of angiotensin-converting enzyme inhibitors on nitrate tolerance during continuous transdermal application of nitroglycerin in patients with chronic heart failure. Nitrates 66-73 angiotensin I converting enzyme Homo sapiens 22-51 9538982-13 1998 Resistance to nitrates, therefore, could be considered another feature of the insulin-resistance syndrome. Nitrates 14-22 insulin Homo sapiens 78-85 9453315-8 1998 Tissue slices of the renal cortex and medulla were studied to determine the effects of Ang II and L-NAME on the nitrite/nitrate production. Nitrates 120-127 angiotensinogen Rattus norvegicus 87-93 9453315-9 1998 Ang II stimulated the nitrite/nitrate production predominately in the renal medulla, which was significantly attenuated by L-NAME. Nitrates 30-37 angiotensinogen Rattus norvegicus 0-6 9456273-2 1998 Up to 8 h after dosing in the morning, more marked and sustained effects were observed with the nitrate (ST at 2 h, -82%; p < 0.001; at 8 h, -64%; p < 0.01) than with molsidomine (2 h, -68%; p < 0.001; at 8 h, -9%; NS). Nitrates 96-103 signal transducer and activator of transcription 2 Homo sapiens 105-112 10684481-2 1998 When nitrates are metabolized to release NO, there is a considerable coproduction of reactive oxygen species (superoxide radical and peroxynitrite) in vessels leading to inactivation of NO, to diminished cyclic quanosine monophosphate production in smooth muscle cells (SMC), to impaired vasomotor responses to the endothelium-derived relaxation factor (EDRF), and to formation of nitrotyrosine as a marker of glyceryltrinitrate (GTN)-induced formation of peroxynitrite. Nitrates 5-13 alpha hemoglobin stabilizing protein Homo sapiens 315-352 10684481-2 1998 When nitrates are metabolized to release NO, there is a considerable coproduction of reactive oxygen species (superoxide radical and peroxynitrite) in vessels leading to inactivation of NO, to diminished cyclic quanosine monophosphate production in smooth muscle cells (SMC), to impaired vasomotor responses to the endothelium-derived relaxation factor (EDRF), and to formation of nitrotyrosine as a marker of glyceryltrinitrate (GTN)-induced formation of peroxynitrite. Nitrates 5-13 alpha hemoglobin stabilizing protein Homo sapiens 354-358 9706250-9 1998 We conclude: 1) in addition to decreased granularity in atrial myocardiocytes, high circulating values of ANF here described suggest an increased turnover of the peptide in 2K2C hypertensive rats; 2) lower significant vascular relaxant effects in HT rats would indicate down regulation of ANF receptors in this model; the latter would derive from high plasma ANF concentration and, tentatively, because of greater activity of protein kinase C in the vascular wall; 39 similar values of plasma nitrite/nitrate in SH and HT rats would indicate a comparable NO circulating availability in both groups. Nitrates 501-508 natriuretic peptide A Rattus norvegicus 106-109 9851362-5 1998 In addition, the above-mentioned changes in iNOS activity and LPO and NP-SH concentrations with lesion development in the gastric mucosa of rats with WIR stress were attenuated with both prevention of the lesion development and an increase in the concentration of gastric mucosal nitrite/nitrate, the breakdown products of NO, by pretreatment with aminoguanidine, a selective iNOS inhibitor. Nitrates 288-295 nitric oxide synthase 2 Rattus norvegicus 44-48 16793713-1 1998 Limited information seems to be available about the role of reduced endothelial production of endotheliumderived relaxing factor (EDRF)-nitrate/nitrite (NO) in the pathogenesis of diabetic angiopathy in insulindependent diabetes. Nitrates 136-143 alpha hemoglobin stabilizing protein Homo sapiens 94-128 16793713-1 1998 Limited information seems to be available about the role of reduced endothelial production of endotheliumderived relaxing factor (EDRF)-nitrate/nitrite (NO) in the pathogenesis of diabetic angiopathy in insulindependent diabetes. Nitrates 136-143 alpha hemoglobin stabilizing protein Homo sapiens 130-134 16793713-5 1998 A significant and inverse correlation of nitrate/nitrite excretion with endothelial markers (von Willebrand factor, soluble thrombomodulin) was documented. Nitrates 41-48 thrombomodulin Homo sapiens 124-138 9455975-0 1997 Changes in nitrite and nitrate (NO2-/NO3-) levels in cerebrospinal fluid of patients with multiple sclerosis. Nitrates 23-30 NBL1, DAN family BMP antagonist Homo sapiens 37-40 9437522-4 1997 Intermediate 5, or the secondary products derived from it, decays to give NO3- and regenerated aldehyde, with small but significant yields of H2O2, organic acids, and organic nitrates. Nitrates 175-183 NBL1, DAN family BMP antagonist Homo sapiens 74-77 9505412-1 1997 Over the last 20 years, dietary nitrate has been implicated in the formation of methemoglobin and carcinogenic nitrosamines in humans. Nitrates 32-39 hemoglobin subunit gamma 2 Homo sapiens 80-93 9421934-8 1997 Compared with plants grown in N-free medium, light-grown plants supplied with nitrate had almost two-fold higher Fd-GOGAT activities and increased Fd-GOGAT mRNA levels, but nitrate had no effect on the abundance of the enzyme or its mRNA in etiolated plants, indicating that light is required for nitrate induction of barley Fd-GOGAT. Nitrates 78-85 ferredoxin-dependent glutamate synthase, Fd-GOGAT Hordeum vulgare 113-121 9421934-8 1997 Compared with plants grown in N-free medium, light-grown plants supplied with nitrate had almost two-fold higher Fd-GOGAT activities and increased Fd-GOGAT mRNA levels, but nitrate had no effect on the abundance of the enzyme or its mRNA in etiolated plants, indicating that light is required for nitrate induction of barley Fd-GOGAT. Nitrates 78-85 ferredoxin-dependent glutamate synthase, Fd-GOGAT Hordeum vulgare 147-155 9421934-8 1997 Compared with plants grown in N-free medium, light-grown plants supplied with nitrate had almost two-fold higher Fd-GOGAT activities and increased Fd-GOGAT mRNA levels, but nitrate had no effect on the abundance of the enzyme or its mRNA in etiolated plants, indicating that light is required for nitrate induction of barley Fd-GOGAT. Nitrates 78-85 ferredoxin-dependent glutamate synthase, Fd-GOGAT Hordeum vulgare 147-155 9366711-9 1997 Nitrite and nitrate levels of the liver, ileum, and blood were higher in the iNOS+/+ mice (P < .05). Nitrates 12-19 nitric oxide synthase 2, inducible Mus musculus 77-81 9378986-6 1997 The PDTC concentration-dependent reductions in iNOS activity produced similar decreases in plasma nitrite/nitrate concentrations. Nitrates 106-113 nitric oxide synthase 2 Rattus norvegicus 47-51 21639276-6 1997 The tip diameter was down to 20 mum, and the sensors exhibited perfectly linear responses to nitrate in both freshwater and seawater. Nitrates 93-100 latexin Homo sapiens 32-35 9312089-5 1997 ATPase activity was strictly dependent on the presence of Na+ or Li+ ions and was inhibited by nitrate, N-ethylmaleimide, and the peptide antibiotic destruxin B. Nitrates 95-102 ATPase Enterococcus faecalis 0-6 9312089-6 1997 When the purified ATPase was reconstituted into liposomes prepared from Enterococcus faecalis phospholipids, ATP-driven Na+ uptake was observed; uptake was blocked by nitrate, destruxin B, and monensin, but it accelerated by carbonyl cyanide m-chlorophenylhydrazone and valinomycin. Nitrates 167-174 ATPase Enterococcus faecalis 18-24 9402285-3 1997 Both follicular nitrite (r = 0.42, P < 0.01) and nitrate (r = 0.49, P < 0.001) were found to be significantly correlated with follicular IL-1beta concentrations. Nitrates 52-59 interleukin 1 beta Homo sapiens 143-151 9402285-5 1997 When follicular cells were incubated in vitro with 10 ng/ml of IL-1beta for 24 h, nitrate generation was significantly (P < 0.01) elevated compared with the control. Nitrates 82-89 interleukin 1 beta Homo sapiens 63-71 9357468-4 1997 We therefore examined whether the plasma levels of nitrite (NO2-) and nitrate (NO3-) ions increased after arterial reconstruction in patients with arteriosclerosis obliterans (ASO). Nitrates 70-77 NBL1, DAN family BMP antagonist Homo sapiens 79-82 9295837-1 1997 OBJECTIVES: To examine the relationship between circulating methemoglobin and nitrite/nitrate concentrations and to compare these markers of nitric oxide overproduction with clinical variables in children diagnosed with septic shock. Nitrates 86-93 hemoglobin subunit gamma 2 Homo sapiens 60-73 9314409-8 1997 Human eNOS gene delivery induces significant increases in urinary and aortic cGMP levels and urinary and serum nitrite/nitrate content (P<.05), while no significant differences in body weight, heart rate, water intake, food consumption, or urine excretion were observed. Nitrates 119-126 nitric oxide synthase 3 Homo sapiens 6-10 9316879-3 1997 We found that chronic proteasome inhibition using MG-341 significantly attenuated the peptidoglycan/polysaccharide (PG/PS)-induced up-regulation of iNOS in the colon and spleen and the consequent increase in plasma levels of nitrate and nitrite. Nitrates 225-232 nitric oxide synthase 2 Homo sapiens 148-152 9242548-5 1997 The NO release from iNOS-transfected cells, as measured by nitrite and nitrate accumulation and by cyclic guanosine monophosphate (cGMP) increases in rat reporter cells, was inhibitable (P < .01 for both) with N(omega)-methyl-L-arginine (L-NMA), a NOS inhibitor. Nitrates 71-78 nitric oxide synthase 2 Rattus norvegicus 20-24 9227507-6 1997 In the current study, we demonstrate that L2 cells generate the oxidative products of NO., nitrite and nitrate, after exposure to tumor necrosis factor-alpha, lipopolysaccharide, and interferon-gamma. Nitrates 103-110 tumor necrosis factor Rattus norvegicus 130-157 9242464-5 1997 Inhibition of iNOS in vivo was confirmed by decreases in plasma nitrite + nitrate concentrations in treated animals compared with that of controls (63-83% decreases for all experiments) and was supported by plasma and tumor concentrations of 1400W that were equivalent and 2.6-4.9 times higher than the EC50 previously reported for iNOS in a tissue assay. Nitrates 74-81 nitric oxide synthase 2, inducible Mus musculus 14-18 9252519-4 1997 Dose-dependent inhibition of interleukin-1 beta- and interferon-gamma-stimulated nitrite/nitrate production was observed when cells were preincubated for 6 h with UDCA (0-800 microM), and a substantial inhibition (81 +/- 3.2%) was seen at 500 microM. Nitrates 89-96 interleukin 1 beta Homo sapiens 29-69 9452775-8 1997 In the case of contraindication or impossibility of using angiotensin converting enzyme inhibitors, a combination of high doses of nitrates and hydralazine may be justified. Nitrates 131-139 angiotensin I converting enzyme Homo sapiens 58-87 9452775-9 1997 On the other hand, when angiotensin converting enzyme inhibitors are already prescribed, nitrates can only be considered to improve symptoms in the case of persistence of dyspnoea. Nitrates 89-97 angiotensin I converting enzyme Homo sapiens 24-53 9201027-6 1997 Production of NO metabolites (nitrate and nitrite), measured as their coronary arteriovenous differencexCBF, was significantly increased after 1 to 2 days of CAR, both at baseline (153 +/- 56%) and during BK infusion (220 +/- 76%) (P < .05). Nitrates 30-37 kininogen 1 Canis lupus familiaris 205-207 12223754-4 1997 SS mRNA was greatly reduced in nodules of drought-, salt-, and nitrate-treated plants; however, this was not correlated with changes in soluble carbohydrate, starch, amino acids, or ureides. Nitrates 63-70 sucrose synthase Glycine max 0-2 9227507-6 1997 In the current study, we demonstrate that L2 cells generate the oxidative products of NO., nitrite and nitrate, after exposure to tumor necrosis factor-alpha, lipopolysaccharide, and interferon-gamma. Nitrates 103-110 interferon gamma Rattus norvegicus 183-199 9133470-4 1997 iNOS expression in allografts resulted in elevated serum nitrite/nitrate levels, indicative of increased in vivo nitric oxide (NO) production. Nitrates 65-72 nitric oxide synthase 2 Rattus norvegicus 0-4 9193097-0 1997 A nitrate-inducible ferredoxin in maize roots. Nitrates 2-9 ferredoxin Zea mays 20-30 9193097-2 1997 We have identified and characterized a nitrate-inducible ferredoxin (Fd) in maize (Zea mays L.) roots by structural analysis of the purified protein and by cloning of its cDNA and gene. Nitrates 39-46 ferredoxin Zea mays 57-67 9193097-2 1997 We have identified and characterized a nitrate-inducible ferredoxin (Fd) in maize (Zea mays L.) roots by structural analysis of the purified protein and by cloning of its cDNA and gene. Nitrates 39-46 ferredoxin Zea mays 69-71 9193097-3 1997 In maize Fd isoproteins are encoded by a small multigene family, and the nitrate-inducible Fd was identified as a novel isoprotein, designated Fd VI, which differed from an Fd I to Fd V identified to date. Nitrates 73-80 ferredoxin Zea mays 9-11 9193097-3 1997 In maize Fd isoproteins are encoded by a small multigene family, and the nitrate-inducible Fd was identified as a novel isoprotein, designated Fd VI, which differed from an Fd I to Fd V identified to date. Nitrates 73-80 ferredoxin Zea mays 91-93 9193097-3 1997 In maize Fd isoproteins are encoded by a small multigene family, and the nitrate-inducible Fd was identified as a novel isoprotein, designated Fd VI, which differed from an Fd I to Fd V identified to date. Nitrates 73-80 ferredoxin-6, chloroplastic Zea mays 143-148 9193097-3 1997 In maize Fd isoproteins are encoded by a small multigene family, and the nitrate-inducible Fd was identified as a novel isoprotein, designated Fd VI, which differed from an Fd I to Fd V identified to date. Nitrates 73-80 ferredoxin Zea mays 91-93 9193097-3 1997 In maize Fd isoproteins are encoded by a small multigene family, and the nitrate-inducible Fd was identified as a novel isoprotein, designated Fd VI, which differed from an Fd I to Fd V identified to date. Nitrates 73-80 ferredoxin Zea mays 91-93 9193097-5 1997 However, during the induction of the capacity for nitrate assimilation, the amount of Fd VI increased markedly within 24 h. Concurrently, the level of transcript for Fd VI increased, but more quickly, reaching a maximal level within 2 h with kinetics similar to those of nitrite reductase and Fd-NADP+ reductase. Nitrates 50-57 ferredoxin-6, chloroplastic Zea mays 86-91 9193097-5 1997 However, during the induction of the capacity for nitrate assimilation, the amount of Fd VI increased markedly within 24 h. Concurrently, the level of transcript for Fd VI increased, but more quickly, reaching a maximal level within 2 h with kinetics similar to those of nitrite reductase and Fd-NADP+ reductase. Nitrates 50-57 ferredoxin-6, chloroplastic Zea mays 166-171 9193097-5 1997 However, during the induction of the capacity for nitrate assimilation, the amount of Fd VI increased markedly within 24 h. Concurrently, the level of transcript for Fd VI increased, but more quickly, reaching a maximal level within 2 h with kinetics similar to those of nitrite reductase and Fd-NADP+ reductase. Nitrates 50-57 ferredoxin--nitrite reductase, chloroplastic Zea mays 271-288 9193097-8 1997 These data indicate that Fd VI is co-induced with the previously characterized enzymes involved in nitrate assimilation, and they suggest that the novel Fd isoprotein, distinct from the constitutively expressed Fd, might play an important role as an electron carrier from NADPH to nitrite reductase and other Fd-dependent enzymes in root plastids. Nitrates 99-106 ferredoxin-6, chloroplastic Zea mays 25-30 9193097-8 1997 These data indicate that Fd VI is co-induced with the previously characterized enzymes involved in nitrate assimilation, and they suggest that the novel Fd isoprotein, distinct from the constitutively expressed Fd, might play an important role as an electron carrier from NADPH to nitrite reductase and other Fd-dependent enzymes in root plastids. Nitrates 99-106 ferredoxin Zea mays 25-27 9193097-8 1997 These data indicate that Fd VI is co-induced with the previously characterized enzymes involved in nitrate assimilation, and they suggest that the novel Fd isoprotein, distinct from the constitutively expressed Fd, might play an important role as an electron carrier from NADPH to nitrite reductase and other Fd-dependent enzymes in root plastids. Nitrates 99-106 ferredoxin Zea mays 153-155 9193097-8 1997 These data indicate that Fd VI is co-induced with the previously characterized enzymes involved in nitrate assimilation, and they suggest that the novel Fd isoprotein, distinct from the constitutively expressed Fd, might play an important role as an electron carrier from NADPH to nitrite reductase and other Fd-dependent enzymes in root plastids. Nitrates 99-106 ferredoxin--nitrite reductase, chloroplastic Zea mays 281-298 9193097-8 1997 These data indicate that Fd VI is co-induced with the previously characterized enzymes involved in nitrate assimilation, and they suggest that the novel Fd isoprotein, distinct from the constitutively expressed Fd, might play an important role as an electron carrier from NADPH to nitrite reductase and other Fd-dependent enzymes in root plastids. Nitrates 99-106 ferredoxin Zea mays 153-155 12223730-3 1997 The induction of nitrate reductase (NR) activity was reduced at both external nitrate concentrations. Nitrates 17-24 nitrate reductase [NADH] 1 Zea mays 36-38 9146896-16 1997 Similarly, segments of rat aorta released detectable levels of nitrite and nitrate, which were reduced by NG-nitro-L-arginine methyl ester (L-NAME, 1 mM), which inhibits all isoforms of NOS, and by dexamethasone (1 microM), which inhibits the induction of iNOS. Nitrates 75-82 nitric oxide synthase 2 Rattus norvegicus 256-260 9211013-2 1997 Additional efficacy stems from the ability of the nitrates to replenish the deficient endothelium-derived relaxing factor (EDRF), nitric oxide (NO), in patients with coronary heart disease and also to inhibit platelet aggregation. Nitrates 50-58 alpha hemoglobin stabilizing protein Homo sapiens 86-121 9211013-2 1997 Additional efficacy stems from the ability of the nitrates to replenish the deficient endothelium-derived relaxing factor (EDRF), nitric oxide (NO), in patients with coronary heart disease and also to inhibit platelet aggregation. Nitrates 50-58 alpha hemoglobin stabilizing protein Homo sapiens 123-127 9211013-12 1997 However, in the GISSI 3 study, the combination of nitrates with an angiotensin-converting enzyme (ACE) inhibitor reduced mortality risks by 17% in patients with acute myocardial infarction. Nitrates 50-58 angiotensin I converting enzyme Homo sapiens 98-101 9136006-1 1997 In Chlamydomonas reinhardtii, the genes required for nitrate assimilation, including the gene encoding nitrate reductase (NIT1), are subject to repression by ammonia. Nitrates 53-60 uncharacterized protein Chlamydomonas reinhardtii 103-120 9136006-1 1997 In Chlamydomonas reinhardtii, the genes required for nitrate assimilation, including the gene encoding nitrate reductase (NIT1), are subject to repression by ammonia. Nitrates 53-60 uncharacterized protein Chlamydomonas reinhardtii 122-126 12237366-6 1997 After adding 12 mM nitrate to nitrate-limited Nia30(145), the transcripts for NR and phosphoenolpyruvate carboxylase increased, and the transcripts for ADP-glucose pyrophosphorylase decreased within 2 and 4 hr, respectively. Nitrates 19-26 phosphoenolpyruvate carboxylase Nicotiana tabacum 85-116 12237366-6 1997 After adding 12 mM nitrate to nitrate-limited Nia30(145), the transcripts for NR and phosphoenolpyruvate carboxylase increased, and the transcripts for ADP-glucose pyrophosphorylase decreased within 2 and 4 hr, respectively. Nitrates 30-37 phosphoenolpyruvate carboxylase Nicotiana tabacum 85-116 9168158-5 1997 A protein-mediated passive transport of nitrate was first demonstrated by the ability of NO3- to electrically short-circuit the (H+)ATPase in plasma membrane vesicles and not in liposomes containing only the purified enzyme. Nitrates 40-47 ATPase Zea mays 129-138 9133470-8 1997 CONCLUSIONS: (1) iNOS expression and increased NO production occurred during the early stages of acute rejection, persisted throughout the unmodified rejection process, and localized to infiltrating inflammatory cells, but not allograft parenchymal cells; (2) aminoguanidine ameliorated the histological and functional changes of acute rejection; and (3) increased NO production, detected by the presence of iNOS mRNA, protein, or noninvasively by measuring serum nitrite/nitrate levels, may serve as an early marker of acute allograft rejection. Nitrates 472-479 nitric oxide synthase 2 Rattus norvegicus 17-21 9161026-1 1997 Higher plant nitrite reductase (NiR) is a monomeric chloroplastic protein catalysing the reduction of nitrite, the product of nitrate reduction, to ammonium. Nitrates 126-133 nitrite reductase 1 Arabidopsis thaliana 13-30 9114772-0 1997 The alpha-1 adrenergic blocking agent urapidil counteracts postrotational atherectomy "elastic recoil" where nitrates have failed. Nitrates 109-117 adrenoceptor alpha 1D Homo sapiens 4-11 9175238-7 1997 An inverse correlation of nitrate/nitrite excretion with endothelial markers (von Willebrand factor, soluble thrombomodulin) was documented in NIDDM, this correlation was much stronger in IDDM. Nitrates 26-33 thrombomodulin Homo sapiens 109-123 9175238-8 1997 Moreover, in IDDM patients reduced nitrate/nitrite excretion was strongly associated with elevated plasmatic beta-thromboglobulin levels. Nitrates 35-42 pro-platelet basic protein Homo sapiens 109-129 9175238-10 1997 In IDDM the decreased nitrate/nitrite excretion may also lead to increased in vivo platelet activation, which suggests that the reduced amount of EDRF-NO might play a role in the pathogenesis of angiopathy in IDDM. Nitrates 22-29 alpha hemoglobin stabilizing protein Homo sapiens 146-150 9281893-1 1997 A simple and sensitive HPLC validated method was developed for the simultaneous determination of ITF 296 (a new orally active nitrate) and its metabolites ITF 1124 and ITF 1577 in biological samples. Nitrates 126-133 trefoil factor 3 Homo sapiens 97-100 9161026-1 1997 Higher plant nitrite reductase (NiR) is a monomeric chloroplastic protein catalysing the reduction of nitrite, the product of nitrate reduction, to ammonium. Nitrates 126-133 nitrite reductase 1 Arabidopsis thaliana 32-35 9161026-5 1997 When these plants were grown in vitro on media containing either nitrate or ammonium as sole nitrogen source, NiR mRNA derived from transgene expression was constitutively expressed, whereas NiR activity and protein level were strongly reduced on ammonium-containing medium. Nitrates 65-72 nitrite reductase 1 Arabidopsis thaliana 110-113 9161026-5 1997 When these plants were grown in vitro on media containing either nitrate or ammonium as sole nitrogen source, NiR mRNA derived from transgene expression was constitutively expressed, whereas NiR activity and protein level were strongly reduced on ammonium-containing medium. Nitrates 65-72 nitrite reductase 1 Arabidopsis thaliana 191-194 9110418-5 1997 Similarly, LPS-induced production of nitrite/nitrate (breakdown products of nitric oxide) was not affected by verapamil and diltiazem. Nitrates 45-52 toll-like receptor 4 Mus musculus 11-14 9023196-0 1997 Cloning and sequence of cymA, a gene encoding a tetraheme cytochrome c required for reduction of iron(III), fumarate, and nitrate by Shewanella putrefaciens MR-1. Nitrates 122-129 cytochrome c Shewanella oneidensis MR-1 24-28 9065390-4 1997 The transformants carrying nit1/ars did not express arylsulphatase when grown in ammonium-sufficient medium but readily accumulated the enzyme in ammonium-free medium either supplemented, or not supplemented, with nitrate or nitrite. Nitrates 214-221 uncharacterized protein Chlamydomonas reinhardtii 27-31 9087877-7 1997 CONCLUSIONS: These results, together with our previous demonstration that iNOS inhibition ameliorated lung allograft rejection, suggest that (1) iNOS expression and increased NO production contributed to acute rejection of the transplanted lung, (2) iNOS inhibition may offer an alternative in management of acute lung allograft rejection, and (3) increased NO production, detected by the presence of iNOS mRNA or protein or noninvasively by measuring serum nitrite/nitrate levels, may serve as an early marker of acute allograft rejection. Nitrates 466-473 nitric oxide synthase 2 Rattus norvegicus 74-78 9071565-4 1997 Serum nitrate levels correlated significantly with both pro-inflammatory cytokines (IL-6, IL-8, TNF-alpha) as well as anti-inflammatory cytokines (IL-10, TNFsrI, TNFsrII). Nitrates 6-13 interleukin 6 Homo sapiens 84-88 9071565-4 1997 Serum nitrate levels correlated significantly with both pro-inflammatory cytokines (IL-6, IL-8, TNF-alpha) as well as anti-inflammatory cytokines (IL-10, TNFsrI, TNFsrII). Nitrates 6-13 C-X-C motif chemokine ligand 8 Homo sapiens 90-94 9071565-4 1997 Serum nitrate levels correlated significantly with both pro-inflammatory cytokines (IL-6, IL-8, TNF-alpha) as well as anti-inflammatory cytokines (IL-10, TNFsrI, TNFsrII). Nitrates 6-13 tumor necrosis factor Homo sapiens 96-105 9071565-4 1997 Serum nitrate levels correlated significantly with both pro-inflammatory cytokines (IL-6, IL-8, TNF-alpha) as well as anti-inflammatory cytokines (IL-10, TNFsrI, TNFsrII). Nitrates 6-13 interleukin 10 Homo sapiens 147-152 9093135-4 1997 NO is an unstable compound with a short half-life;it is easily converted to nitrite (NO2) and nitrate (NO3). Nitrates 94-101 NBL1, DAN family BMP antagonist Homo sapiens 103-106 9085575-2 1997 We demonstrated previously that 238 and 330 bp of the 5" flanking regions, designated as NP1 and NP2, of the two nitrate reductase genes NR1 and NR2, respectively, are sufficient for nitrate-dependent transcription (Y. Lin, C.-F. Hwang, J.B. Brown, C.-L. Cheng [1994] Plant Physiol 106: 477-484). Nitrates 113-120 NPK1-related protein kinase 1 Arabidopsis thaliana 89-92 9085575-2 1997 We demonstrated previously that 238 and 330 bp of the 5" flanking regions, designated as NP1 and NP2, of the two nitrate reductase genes NR1 and NR2, respectively, are sufficient for nitrate-dependent transcription (Y. Lin, C.-F. Hwang, J.B. Brown, C.-L. Cheng [1994] Plant Physiol 106: 477-484). Nitrates 113-120 NPK1-related protein kinase 2 Arabidopsis thaliana 97-100 9085575-2 1997 We demonstrated previously that 238 and 330 bp of the 5" flanking regions, designated as NP1 and NP2, of the two nitrate reductase genes NR1 and NR2, respectively, are sufficient for nitrate-dependent transcription (Y. Lin, C.-F. Hwang, J.B. Brown, C.-L. Cheng [1994] Plant Physiol 106: 477-484). Nitrates 113-120 nitrate reductase 1 Arabidopsis thaliana 137-140 9085575-2 1997 We demonstrated previously that 238 and 330 bp of the 5" flanking regions, designated as NP1 and NP2, of the two nitrate reductase genes NR1 and NR2, respectively, are sufficient for nitrate-dependent transcription (Y. Lin, C.-F. Hwang, J.B. Brown, C.-L. Cheng [1994] Plant Physiol 106: 477-484). Nitrates 113-120 nitrate reductase 2 Arabidopsis thaliana 145-148 9085575-3 1997 Here we identify the cis-acting elements of NP1 and NP2 that are necessary for nitrate-dependent transcription by linker-scanning (LS) analysis. Nitrates 79-86 NPK1-related protein kinase 1 Arabidopsis thaliana 44-47 9085575-3 1997 Here we identify the cis-acting elements of NP1 and NP2 that are necessary for nitrate-dependent transcription by linker-scanning (LS) analysis. Nitrates 79-86 NPK1-related protein kinase 2 Arabidopsis thaliana 52-55 9085575-4 1997 In transgenic plants one LS mutant of NP1 and two LS mutants of NP2 exhibited significantly lower nitrate-induced reporter gene chloramphenicol acetyltransferase activity. Nitrates 98-105 NPK1-related protein kinase 1 Arabidopsis thaliana 38-41 9085575-4 1997 In transgenic plants one LS mutant of NP1 and two LS mutants of NP2 exhibited significantly lower nitrate-induced reporter gene chloramphenicol acetyltransferase activity. Nitrates 98-105 NPK1-related protein kinase 2 Arabidopsis thaliana 64-67 9085575-6 1997 The single LS mutant in NP1 lost its response to nitrate, whereas the two LS mutants in NP2 partially lost their response to nitrate. Nitrates 49-56 NPK1-related protein kinase 1 Arabidopsis thaliana 24-27 9085575-6 1997 The single LS mutant in NP1 lost its response to nitrate, whereas the two LS mutants in NP2 partially lost their response to nitrate. Nitrates 125-132 NPK1-related protein kinase 2 Arabidopsis thaliana 88-91 9023196-2 1997 This gene complemented a mutant which had a TnphoA insertion in cymA and which was deficient in the respiratory reduction of iron(III), nitrate, fumarate, and manganese(IV). Nitrates 136-143 cytochrome c Shewanella oneidensis MR-1 64-68 9020872-0 1997 The YNT1 gene encoding the nitrate transporter in the yeast Hansenula polymorpha is clustered with genes YNI1 and YNR1 encoding nitrite reductase and nitrate reductase, and its disruption causes inability to grow in nitrate. Nitrates 27-34 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 4-8 9020872-2 1997 Disruption of the chromosomal YNT1 copy resulted in incapacity to grow in nitrate and a significant reduction in rate of nitrate uptake. Nitrates 74-81 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 30-34 9020872-2 1997 Disruption of the chromosomal YNT1 copy resulted in incapacity to grow in nitrate and a significant reduction in rate of nitrate uptake. Nitrates 121-128 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 30-34 9020872-4 1997 Northern-blot analysis showed that YNT1 is expressed when the yeast is grown in nitrate and nitrite but not in ammonium solution. Nitrates 80-87 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 35-39 8994427-11 1997 CONCLUSIONS: The three main classes of antianginal medication have different and possible clinically relevant effects on platelet behavior in vivo, nitrates causing inhibition of aggregation (fibrinogen binding) and degranulation (P-selectin expression), calcium antagonists enhancing degranulation, and beta-blockers enhancing aggregation. Nitrates 148-156 fibrinogen beta chain Homo sapiens 192-202 8994427-11 1997 CONCLUSIONS: The three main classes of antianginal medication have different and possible clinically relevant effects on platelet behavior in vivo, nitrates causing inhibition of aggregation (fibrinogen binding) and degranulation (P-selectin expression), calcium antagonists enhancing degranulation, and beta-blockers enhancing aggregation. Nitrates 148-156 selectin P Homo sapiens 231-241 8995407-5 1997 The spectra obtained for the adducts formed with halides, pseudohalides, trichloroacetate, nitrate, imidazole, and 1-methylimidazole appear to be representative of near tetrahedral Co(II) geometries. Nitrates 91-98 mitochondrially encoded cytochrome c oxidase II Homo sapiens 181-187 9001323-6 1997 Antibodies to TNF and/or IL-1 significantly reduced the nitrite or nitrite + nitrate concentrations and the concentrations of TNF and IL-1 in the M-CM correlated with nitrite concentrations in the LA-4 culture supernatant fluids (r2 = 0.848 and 0.956). Nitrates 77-84 tumor necrosis factor Mus musculus 14-17 9001323-6 1997 Antibodies to TNF and/or IL-1 significantly reduced the nitrite or nitrite + nitrate concentrations and the concentrations of TNF and IL-1 in the M-CM correlated with nitrite concentrations in the LA-4 culture supernatant fluids (r2 = 0.848 and 0.956). Nitrates 77-84 interleukin 1 complex Mus musculus 25-29 9503598-4 1997 The ranges of SCP under the influence of temperature, light, nitrate, ammonia, phosphorus, iron, carbonate, and sodium chloride were in the following respective order (% dry wt): 18.4-43.3, 20.5-42.3, 12.4-35.8, 15.7-41.8, 15.8-49.4, 17.4-49.7, 13.8-35.6, and 0.0-37.7. Nitrates 61-68 solute carrier family 50 member 1 Homo sapiens 14-17 8799195-1 1996 Two mutations have been found in a gene (NRT2) of Arabidopsis thaliana that specifically impair constitutive, high-affinity nitrate uptake. Nitrates 124-131 nitrate transporter 2:1 Arabidopsis thaliana 41-45 8985206-8 1997 Nitrite accumulation in experiments with IFN-gamma/IL-4 in human monocytes appears to be an in vitro artifact produced by nitrate-reducing activities contained in cytokine preparations. Nitrates 122-129 interferon gamma Homo sapiens 41-50 8985206-8 1997 Nitrite accumulation in experiments with IFN-gamma/IL-4 in human monocytes appears to be an in vitro artifact produced by nitrate-reducing activities contained in cytokine preparations. Nitrates 122-129 interleukin 4 Homo sapiens 51-55 9010412-0 1997 A rostrocaudal gradient of nitrate plus nitrite concentrations in CSF. Nitrates 27-34 colony stimulating factor 2 Homo sapiens 66-69 9035296-8 1997 The plasma level of nitrate/nitrite increased from 20 to 260 and 1000 microM 4 and 16 h, respectively, 20 mg/kg NMLA abolished NO production at 4 h, while MP inhibited it for up to 16 h. The hepatic malondialdehyde level increased from 0.50 to 2.46 nmol/mg protein at 4 h. Administration of anti-CD18 and MP reduced the level to 1.80 and 1.41 nmol/mg protein, respectively, whereas NMLA did not affect it. Nitrates 20-27 integrin beta 2 Mus musculus 296-300 8938409-5 1996 CYCD3 (delta 3) transcript levels were strongly dependent on nitrate, and were induced at the G1/S transition following phytohormone readdition. Nitrates 61-68 CYCLIN D3;1 Arabidopsis thaliana 0-5 8883421-0 1996 Plasma nitrate plus nitrite changes during continuous intravenous infusion interleukin 2. Nitrates 7-14 interleukin 2 Homo sapiens 75-88 8883421-12 1996 We conclude that determination of plasma nitrate + nitrite levels during CIVI IL-2 can usefully estimate, in a dose-dependent pattern, the degree of peripheral vascular relaxation and capillary leakage associated with cytokine action, clinically manifested as hypotension. Nitrates 41-48 interleukin 2 Homo sapiens 78-82 8864137-20 1996 Serum levels of tumor necrosis factor-alpha (TNF-alpha and nitrite/nitrate in IFN-gamma-treated mice were similar to those of controls. Nitrates 67-74 interferon gamma Mus musculus 78-87 8912158-11 1996 After RY, nitrite/nitrate concentration increased to 22.7 +/- 30.1, 32.4 +/- 21.4 and 44.6 +/- 32.7 mol/l in RY1, RY2 and RY3, respectively; in RY45, serum nitrite/nitrate concentration was normal averaging 6.1 +/- 1.2 mol/l. Nitrates 18-25 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 Rattus norvegicus 109-112 8884978-9 1996 On study admission and at 2-h intervals, plasma CGRP concentrations correlated directly with nitrite and nitrate values. Nitrates 105-112 calcitonin related polypeptide alpha Homo sapiens 48-52 8923042-3 1996 Maximal plasma concentrations of nitrate plus nitrite were correlated to the degree of hypotension (r = -0.64, p = 0.02) and levels of tumor necrosis factor (TNF)-alpha (r = 0.51, p = 0.05) and soluble TNF receptors p55 and p75 (r = 0.58, p = 0.03 and r = 0.54, p = 0.04, respectively) but not to levels of interferon-gamma or interleukin-10 (p > 0.05). Nitrates 33-40 TNF receptor superfamily member 1A Homo sapiens 216-219 8923042-3 1996 Maximal plasma concentrations of nitrate plus nitrite were correlated to the degree of hypotension (r = -0.64, p = 0.02) and levels of tumor necrosis factor (TNF)-alpha (r = 0.51, p = 0.05) and soluble TNF receptors p55 and p75 (r = 0.58, p = 0.03 and r = 0.54, p = 0.04, respectively) but not to levels of interferon-gamma or interleukin-10 (p > 0.05). Nitrates 33-40 TNF receptor superfamily member 1B Homo sapiens 224-227 8923042-3 1996 Maximal plasma concentrations of nitrate plus nitrite were correlated to the degree of hypotension (r = -0.64, p = 0.02) and levels of tumor necrosis factor (TNF)-alpha (r = 0.51, p = 0.05) and soluble TNF receptors p55 and p75 (r = 0.58, p = 0.03 and r = 0.54, p = 0.04, respectively) but not to levels of interferon-gamma or interleukin-10 (p > 0.05). Nitrates 33-40 interferon gamma Homo sapiens 307-323 8923042-3 1996 Maximal plasma concentrations of nitrate plus nitrite were correlated to the degree of hypotension (r = -0.64, p = 0.02) and levels of tumor necrosis factor (TNF)-alpha (r = 0.51, p = 0.05) and soluble TNF receptors p55 and p75 (r = 0.58, p = 0.03 and r = 0.54, p = 0.04, respectively) but not to levels of interferon-gamma or interleukin-10 (p > 0.05). Nitrates 33-40 interleukin 10 Homo sapiens 327-341 9411502-4 1997 The mean +/- levels of nitrite and nitrate in CSF on admission were higher in patients with BM in comparison with controls and in children with viral meningitis. Nitrates 35-42 colony stimulating factor 2 Homo sapiens 46-49 8981915-13 1996 Treatment with recombinant human growth hormone normalizes urinary nitrate and cyclic GMP excretion, possibly via IGF-1 stimulation of endothelial NO formation, and concomitantly decreases peripheral arterial resistance. Nitrates 67-74 growth hormone 1 Homo sapiens 33-47 8943494-1 1996 Nitric oxide (NO) is readily oxidized to nitrate and nitrite and NO activates guanylyl cyclase, increasing cyclic GMP levels. Nitrates 41-48 5'-nucleotidase, cytosolic II Homo sapiens 114-117 8989878-0 1996 CHL1 encodes a component of the low-affinity nitrate uptake system in Arabidopsis and shows cell type-specific expression in roots. Nitrates 45-52 nitrate transporter 1.1 Arabidopsis thaliana 0-4 8989878-1 1996 The Arabidopsis CHL1 (AtNRT1) gene confers sensitivity to the herbicide chlorate and encodes a nitrate-regulated nitrate transporter. Nitrates 95-102 nitrate transporter 1.1 Arabidopsis thaliana 16-20 8989878-1 1996 The Arabidopsis CHL1 (AtNRT1) gene confers sensitivity to the herbicide chlorate and encodes a nitrate-regulated nitrate transporter. Nitrates 95-102 nitrate transporter 1.1 Arabidopsis thaliana 22-28 8989878-2 1996 However, how CHL1 participates in nitrate uptake in plants is not yet clear. Nitrates 34-41 nitrate transporter 1.1 Arabidopsis thaliana 13-17 8989878-4 1996 Under most conditions tested, the amount of nitrate uptake by a chl1 deletion mutant was found to be significantly less than that of the wild type. Nitrates 44-51 nitrate transporter 1.1 Arabidopsis thaliana 64-68 8989878-7 1996 These results are consistent with the involvement of CHL1 in nitrate uptake at different stages of root cell development. Nitrates 61-68 nitrate transporter 1.1 Arabidopsis thaliana 53-57 8989878-8 1996 A functional analysis in Xenopus oocytes indicated that CHL1 is a low-affinity nitrate transporter with a K(m) value of approximately 8.5 mM for nitrate. Nitrates 79-86 DEAD/H-box helicase 11 L homeolog Xenopus laevis 56-60 8937711-18 1996 in conscious unrestrained rats, 2-amino-4-methylpyridine inhibited the rise in plasma nitrate produced in response to intraperitoneal injection of LPS (ID50 = 0.009 mg kg-1 min-1). Nitrates 86-93 toll-like receptor 4 Mus musculus 147-150 8937711-23 1996 2-Amino-4-methylpyridine also inhibited LPS-induced elevation in plasma nitrate after either subcutaneous (ID50 = 0.3 mg kg-1) or oral (ID50 = 20.8 mg kg-1) administration. Nitrates 72-79 toll-like receptor 4 Mus musculus 40-43 8953249-4 1996 Transcripts for ZmSUMT1 accumulated rapidly in both rots and leaves in response to the addition of nitrate to the culture medium. Nitrates 99-106 siroheme uroporphyrinogen methyltransferase 1 Zea mays 16-23 8953249-5 1996 The effects of biochemical inhibitors on the nitrate-dependent induction of the gene for ZmSUMT1 coincided with the effects on the genes for other nitrate-assimilatory enzymes, nitrate reductase and nitrite reductase. Nitrates 45-52 siroheme uroporphyrinogen methyltransferase 1 Zea mays 89-96 8953249-5 1996 The effects of biochemical inhibitors on the nitrate-dependent induction of the gene for ZmSUMT1 coincided with the effects on the genes for other nitrate-assimilatory enzymes, nitrate reductase and nitrite reductase. Nitrates 45-52 nitrate reductase [NADH] 1 Zea mays 177-194 8953249-5 1996 The effects of biochemical inhibitors on the nitrate-dependent induction of the gene for ZmSUMT1 coincided with the effects on the genes for other nitrate-assimilatory enzymes, nitrate reductase and nitrite reductase. Nitrates 45-52 ferredoxin--nitrite reductase, chloroplastic Zea mays 199-216 8953249-5 1996 The effects of biochemical inhibitors on the nitrate-dependent induction of the gene for ZmSUMT1 coincided with the effects on the genes for other nitrate-assimilatory enzymes, nitrate reductase and nitrite reductase. Nitrates 147-154 siroheme uroporphyrinogen methyltransferase 1 Zea mays 89-96 8953249-7 1996 The results together indicate that ZmSUMT1 might be involved in the synthesis of siroheme, a prosthetic group of nitrite reductase, and that the expression of its gene is co-regulated with that of other nitrate-assimilatory genes. Nitrates 203-210 siroheme uroporphyrinogen methyltransferase 1 Zea mays 35-42 8906612-4 1996 In addition, the mutant SOD protein may function as a peroxidase to oxidize cellular components, and it may also react with peroxynitrite-a product of the reaction between superoxide and nitric oxide-to ultimately form nitrate proteins. Nitrates 219-226 superoxide dismutase 1 Homo sapiens 24-27 8902940-5 1996 Selective inhibition of iNOS with mercaptoethylguanidine (MEG) reduced plasma nitrite/nitrate levels, but did not prevent the development of vascular hyporeactivity, and did not improve survival in this model of CLP. Nitrates 86-93 nitric oxide synthase 2 Rattus norvegicus 24-28 8806782-11 1996 However, ONOO., formed by the reaction of .NO and O2.-, nitrates SP-A leading to decreased ability to aggregate lipids and bind mannose. Nitrates 56-64 surfactant protein A1 Homo sapiens 65-69 8950496-14 1996 Patients taking nitrates had lower activation; after eliminating these patients, GPIIb/IIIa ligand binding was greater among patients with restenosis at both 1 and 2 min (P = 0.04 for both). Nitrates 16-24 integrin subunit alpha 2b Homo sapiens 81-86 8921069-2 1996 Our aim was to study follicular nitrite and nitrate (NO3/NO2) levels in women undergoing in-vitro fertilization (IVF), and to examine their relationship to follicular size, oestradiol concentrations, and ovarian artery and intra-ovarian blood flow as measured by Doppler ultrasound. Nitrates 44-51 NBL1, DAN family BMP antagonist Homo sapiens 53-56 8923042-3 1996 Maximal plasma concentrations of nitrate plus nitrite were correlated to the degree of hypotension (r = -0.64, p = 0.02) and levels of tumor necrosis factor (TNF)-alpha (r = 0.51, p = 0.05) and soluble TNF receptors p55 and p75 (r = 0.58, p = 0.03 and r = 0.54, p = 0.04, respectively) but not to levels of interferon-gamma or interleukin-10 (p > 0.05). Nitrates 33-40 tumor necrosis factor Homo sapiens 135-168 9064335-6 1996 Blood mononuclear cells from RA patients had increased NOS activity and increased NOS2 antigen content as compared to those from normal subjects, and responded to interferon-gamma with increased NOS expression and nitrite/nitrate production in vitro. Nitrates 222-229 interferon gamma Homo sapiens 163-179 8799195-7 1996 These results indicate that NRT2 is a critical and perhaps necessary gene for constitutive, high-affinity nitrate uptake in Arabidopsis, but not for inducible, high-affinity nor constitutive, low-affinity nitrate uptake. Nitrates 106-113 nitrate transporter 2:1 Arabidopsis thaliana 28-32 8702535-5 1996 Planar nitrate, NO3-, is isosteric with the PO3 moiety of a phosphotransfer transition state. Nitrates 7-14 NBL1, DAN family BMP antagonist Homo sapiens 16-19 9132576-1 1996 Health effects associated with ingestion of nitrate-contaminated water have included methemoglobinemia (i.e., blue baby syndrome) in infants and spontaneous abortions in laboratory animals and livestock; however, only one study in humans has reported an association between increased methemoglobin levels and spontaneous abortion. Nitrates 44-51 hemoglobin subunit gamma 2 Homo sapiens 85-98 8760140-2 1996 Stimulation of rat pleural mesothelial cells with combinations of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and LPS induced the synthesis of nitric oxide as measured by the oxidation products nitrite (NO2-) and nitrate (NO3-). Nitrates 272-279 interleukin 1 beta Rattus norvegicus 66-84 8760140-2 1996 Stimulation of rat pleural mesothelial cells with combinations of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and LPS induced the synthesis of nitric oxide as measured by the oxidation products nitrite (NO2-) and nitrate (NO3-). Nitrates 272-279 tumor necrosis factor Rattus norvegicus 98-125 8760140-2 1996 Stimulation of rat pleural mesothelial cells with combinations of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and LPS induced the synthesis of nitric oxide as measured by the oxidation products nitrite (NO2-) and nitrate (NO3-). Nitrates 272-279 interferon gamma Rattus norvegicus 139-155 8760140-2 1996 Stimulation of rat pleural mesothelial cells with combinations of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and LPS induced the synthesis of nitric oxide as measured by the oxidation products nitrite (NO2-) and nitrate (NO3-). Nitrates 272-279 interferon gamma Rattus norvegicus 157-166 8694791-7 1996 In the presence of nitrate the delta ynil::URA3 mutant extrudes approx. Nitrates 19-26 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 43-47 8842573-9 1996 The subsequent drop in plasma nitrate, with a t1/2 of 451 +/- 42 min, was probably a reflection of the redistribution of nitrate within the body fluids and the renal excretion of nitrate. Nitrates 30-37 interleukin 1 receptor like 1 Homo sapiens 46-68 8842573-9 1996 The subsequent drop in plasma nitrate, with a t1/2 of 451 +/- 42 min, was probably a reflection of the redistribution of nitrate within the body fluids and the renal excretion of nitrate. Nitrates 121-128 interleukin 1 receptor like 1 Homo sapiens 46-68 8842573-9 1996 The subsequent drop in plasma nitrate, with a t1/2 of 451 +/- 42 min, was probably a reflection of the redistribution of nitrate within the body fluids and the renal excretion of nitrate. Nitrates 121-128 interleukin 1 receptor like 1 Homo sapiens 46-68 8844437-2 1996 It appears to relax vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and, like nitrates, through an increase in intracellular cyclic GMP. Nitrates 138-146 5'-nucleotidase, cytosolic II Homo sapiens 192-195 8674325-8 1996 Children with increased plasma IL-6 concentrations (n = 6) had increased plasma nitrite/nitrate concentrations (p < 0.01 on each day), increased organ failure scores (p < .05 on days 1 and 3), and the highest plasma IL-10 concentrations (p < .05 on days 1 and 3, p = .054 on day 2) when compared with children with sepsis and undetectable IL-6 concentrations. Nitrates 88-95 interleukin 6 Homo sapiens 31-35 8674325-9 1996 Children with sepsis and detectable IL-6 concentrations, and children with undetectable IL-6 concentrations, both had increased nitrite/nitrate concentrations (p < .005 on days 1 through 3) and increased IL-10 concentrations (p < .05 on days 1 and 2) compared with controls. Nitrates 136-143 interleukin 6 Homo sapiens 88-92 8651088-1 1996 Nitrate tolerance has been reported to be reversed by certain types of angiotensin-converting enzyme (ACE) inhibitors. Nitrates 0-7 angiotensin I converting enzyme Homo sapiens 71-100 8651088-1 1996 Nitrate tolerance has been reported to be reversed by certain types of angiotensin-converting enzyme (ACE) inhibitors. Nitrates 0-7 angiotensin I converting enzyme Homo sapiens 102-105 8651088-8 1996 In conclusion, a single oral administration of the ACE inhibitor alacepril (50mg) elicited beneficial effects against exercise-induced myocardial ischemia in patients with stable effort angina during chronic nitrate treatment. Nitrates 208-215 angiotensin I converting enzyme Homo sapiens 51-54 8640982-0 1996 Long-term angiotensin-converting enzyme inhibition with high-dose enalapril retards nitrate tolerance in large epicardial arteries and prevents rebound coronary vasoconstriction in vivo. Nitrates 84-91 angiotensin I converting enzyme Homo sapiens 10-39 16535328-9 1996 The positive reaction to nitrate overruled a negative response to oxygen, indicating that nitrate is the principal electron acceptor used by Thioploca spp. Nitrates 25-32 histocompatibility minor 13 Homo sapiens 151-154 16535328-9 1996 The positive reaction to nitrate overruled a negative response to oxygen, indicating that nitrate is the principal electron acceptor used by Thioploca spp. Nitrates 90-97 histocompatibility minor 13 Homo sapiens 151-154 8689594-6 1996 Greenfeed often contains high levels of nitrate (NO3-), which is known to impair thyroid gland function. Nitrates 40-47 NBL1, DAN family BMP antagonist Homo sapiens 49-52 8640982-13 1996 The present study also favors a combination of nitroglycerin and ACE inhibitors to maintain nitrate sensitivity of the vasculature during long-term nitroglycerin treatment. Nitrates 92-99 angiotensin I converting enzyme Homo sapiens 65-68 8638526-7 1996 Recent information suggests that nitrate tolerance is caused by increased levels of superoxide at the vascular wall, which leads to reduced nitric oxide level and to increased sensitivity to vasoconstrictive mechanisms, such as endothelin and angiotensin II. Nitrates 33-40 angiotensinogen Homo sapiens 228-257 8761850-7 1996 In both nitrate-tolerant and nontolerant coronary arteries, glibenclamide (GLI 10(-6) M), a selective KATP channel blocker, caused a parallel rightward shift in the concentration-response curve to cromakalim, but had no effect on responses to NTG or SNP. Nitrates 8-15 GLI family zinc finger 1 Homo sapiens 75-78 8761850-8 1996 In nontolerant coronary arteries, GLI had no effect on NIC-induced relaxation, but in nitrate-tolerant preparations, GLI produced a significant rightward shift in the NIC concentration-response curve. Nitrates 86-93 GLI family zinc finger 1 Homo sapiens 117-120 8854644-14 1996 Subcutaneous IL-2 treatment strongly induced nitric oxide synthesis (up to 3.5 mumoles of urinary nitrate/ mouse/day). Nitrates 98-105 interleukin 2 Mus musculus 13-17 8871401-2 1996 Here, we focus on two proteins that contain iron-sulfur clusters, the fumarate nitrate reduction (FNR) protein of Escherichia coli and mammalian iron-responsive-element-binding protein 1 (IRP1), both of which function as direct sensors of oxygen and iron levels. Nitrates 79-86 aconitase 1 Homo sapiens 145-186 8804922-3 1996 Following injection of endotoxin (bacterial lipopolysaccharide) in rats we detected increased inducible NO synthase mRNA levels in the left ventricular wall within 30 min which then peaked at 3 h. This was followed by an increase in myocardial inducible NO synthase enzyme activity and plasma levels of NO metabolites, nitrate and nitrite, which peaked at 6 and 12 h, respectively. Nitrates 319-326 nitric oxide synthase 2 Rattus norvegicus 94-115 8928839-2 1996 The infusion of myoglobin (375 mg/kg) resulted in a decrease in renal blood flow, an increase in renal vascular resistance, and a decrease in creatine clearance associated with a decrease in urinary excretory rate of nitrite/nitrate and guanosine 3",5"-cyclic monophosphate (cGMP). Nitrates 225-232 LOW QUALITY PROTEIN: myoglobin Oryctolagus cuniculus 16-25 16535314-5 1996 Nitrate inhibited As(V) reduction by its action as a preferred respiratory electron acceptor rather than as a structural analog of As(V). Nitrates 0-7 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 18-23 16535314-5 1996 Nitrate inhibited As(V) reduction by its action as a preferred respiratory electron acceptor rather than as a structural analog of As(V). Nitrates 0-7 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 131-136 16535314-6 1996 Nitrate-respiring sediments could reduce As(V) to As(III) once all the nitrate was removed. Nitrates 0-7 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 41-46 16535314-6 1996 Nitrate-respiring sediments could reduce As(V) to As(III) once all the nitrate was removed. Nitrates 71-78 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 41-46 16535314-7 1996 Chloramphenicol blocked the reduction of As(V) to As(III) in nitrate-respiring sediments, suggesting that nitrate and arsenate were reduced by separate enzyme systems. Nitrates 61-68 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 41-46 16535314-7 1996 Chloramphenicol blocked the reduction of As(V) to As(III) in nitrate-respiring sediments, suggesting that nitrate and arsenate were reduced by separate enzyme systems. Nitrates 106-113 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 41-46 8620596-6 1996 iNOS mRNA was expressed in the allograft heart and native lung and was associated with increased serum nitrite/nitrate levels. Nitrates 111-118 nitric oxide synthase 2 Rattus norvegicus 0-4 8620596-7 1996 iNOS inhibition with aminoguanidine prevented or attenuated allograft heart and systemic vascular barrier dysfunction and reduced allograft serum nitrite/nitrate levels to isograft values. Nitrates 154-161 nitric oxide synthase 2 Rattus norvegicus 0-4 8743440-0 1996 Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines. Nitrates 0-7 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 59-63 8743440-10 1996 In conclusion, consumption of drinking water, especially well water, with high nitrate levels can imply a genotoxic risk for humans as indicated by increased HPRT variant frequencies and by endogenous formation of carcinogenic N-nitroso compounds from nitrate-derived nitrite. Nitrates 79-86 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 158-162 8621213-3 1996 Therefore, we designed these studies to test the hypothesis that Ang II exerts time-dependent effects on renal NO generation as assessed from renal excretion of nitrate and nitrite, percent increases in renal vascular resistance during inhibition of NO synthase with intravenous NG -nitro-L-arginine methyl ester (L-NAME), or decreases in renal vascular resistance during stimulation of endothelial NO synthase with intravenous acetylcholine. Nitrates 161-168 angiotensinogen Rattus norvegicus 65-71 8621213-6 1996 The renal excretion of nitrate and nitrite was increased during short-term Ang II infusions (from 205 +/- 22 to 331 +/- 58 pmol.min-1, P < .05) but was unchanged during prolonged Ang II infusion (control group, 197 +/- 33 versus Ang II, 245 +/- 42 pmol.min-1, P=NS). Nitrates 23-30 angiotensinogen Rattus norvegicus 75-81 8859948-1 1996 Whether the arterial elastic structures are involved in the beneficial effects of long-term treatment with organic nitrates on atherosclerosis-induced changes in hemodynamics and arterial wall viscoelastic properties, are case for angiotensin-converting enzyme (ACE) inhibitors, is not known. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 231-260 8859948-1 1996 Whether the arterial elastic structures are involved in the beneficial effects of long-term treatment with organic nitrates on atherosclerosis-induced changes in hemodynamics and arterial wall viscoelastic properties, are case for angiotensin-converting enzyme (ACE) inhibitors, is not known. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 262-265 8630708-9 1996 ANP was higher in subjects with jugular venous pressure > 10 cm, presence of a third heart sound, peripheral edema, artificial cardiac pacemaker, atrial arrhythmias, and in those taking digoxin, diuretics, or nitrates. Nitrates 212-220 natriuretic peptide A Homo sapiens 0-3 8630708-10 1996 On multivariate analysis independent predictors of ANP levels were, in descending order, nitrates, age, diuretics, and atrial arrhythmias. Nitrates 89-97 natriuretic peptide A Homo sapiens 51-54 8871401-2 1996 Here, we focus on two proteins that contain iron-sulfur clusters, the fumarate nitrate reduction (FNR) protein of Escherichia coli and mammalian iron-responsive-element-binding protein 1 (IRP1), both of which function as direct sensors of oxygen and iron levels. Nitrates 79-86 aconitase 1 Homo sapiens 188-192 8627326-0 1996 Ex vivo measurement of brain tissue nitrite and nitrate accurately reflects nitric oxide synthase activity in vivo. Nitrates 48-55 nitric oxide synthase 2 Homo sapiens 76-97 8627326-1 1996 The ex vivo tissue concentration of nitrite and nitrate (NOx) was found to correlate closely with the activity of nitric oxide synthase (NOS; EC 1.14.13.39) in various brain regions. Nitrates 48-55 nitric oxide synthase 2 Homo sapiens 114-135 8661258-1 1996 Gd3+ is shown to be an effective shift reagent for 14N and 15N nitrate NMR signals, resolving the internal and external nitrate signals in plant tissues, including cell suspensions and root material. Nitrates 63-70 GRDX Homo sapiens 0-3 8661258-1 1996 Gd3+ is shown to be an effective shift reagent for 14N and 15N nitrate NMR signals, resolving the internal and external nitrate signals in plant tissues, including cell suspensions and root material. Nitrates 120-127 GRDX Homo sapiens 0-3 8661258-2 1996 However, time-course experiments show that, while the use of Gd3+ allows nitrate levels to be monitored over extended periods, it also has adverse effects on growth and nitrate uptake. Nitrates 73-80 GRDX Homo sapiens 61-64 8661258-2 1996 However, time-course experiments show that, while the use of Gd3+ allows nitrate levels to be monitored over extended periods, it also has adverse effects on growth and nitrate uptake. Nitrates 169-176 GRDX Homo sapiens 61-64 12226271-0 1996 Appearance of Novel Glucose-6-Phosphate Dehydrogenase Isoforms in Chlamydomonas reinhardtii during Growth on Nitrate. Nitrates 109-116 uncharacterized protein Chlamydomonas reinhardtii 20-53 8731510-2 1996 We observed that insulin at concentration in the range 0.25-2 nmol/L decreases platelet response to adenosine 5-diphosphate (ADP), being Effective Dose 50 (ED50) for ADP with 2 nmol/L insulin 164 +/- 15% of the basal value, p = 0.005; furthermore, insulin increases intraplatelet content of cGMP (from basal 7.3 +/-0.6 pmol/10(9) plts to 14.6 +/- 1.2 pmol/10(9) plts with 2 nmol/L insulin, p=0.0001) and does not affect the platelet cGMP increase induced by nitrates. Nitrates 458-466 insulin Homo sapiens 17-24 8731510-3 1996 On the contrary, at very elevated concentrations (25-200 nmol/L) insulin increases platelet aggregation to ADP (ADP ED50 with 200 nmol/L insulin being 81 +/- 4% of the basal value, p = 0.01), decreases intraplatelet content of cGMP (from basal 7.2 +/- 0.1 pmol/10(9) plts to 5.7 +/- 0.2 pmol/10(9) plts with 200 nmol/L insulin, p = 0.01) and attenuates the platelet cGMP increase induced by nitrates. Nitrates 391-399 insulin Homo sapiens 65-72 8754362-9 1996 For patients who cannot take an ACE inhibitor the combination of hydralazine and nitrates may offer some prognostic benefit. Nitrates 81-89 angiotensin I converting enzyme Homo sapiens 32-35 8924591-13 1996 The most important variables, associated with both mutagenicity and Ah receptor affinity, included 1-nitropyrene, particle bound nitrate, indeno[1,2,3-cd]pyrene, and emitted mass of particles. Nitrates 129-136 aryl hydrocarbon receptor Homo sapiens 68-79 8739090-1 1996 The urinary excretion rates of nitrate (NO3) and nitrite (NO2) were monitored in 14 patients with active ulcerative colitis during treatment using hydrocortisone and sulfasalazine. Nitrates 31-38 NBL1, DAN family BMP antagonist Homo sapiens 40-43 8647309-9 1996 The nitrate levels were in the range 1-2.6 mg/kg NO3- for fresh milk and 1.1-18 mg/kg NO3- for dry milk. Nitrates 4-11 NBL1, DAN family BMP antagonist Homo sapiens 49-52 8598489-0 1996 IL-1 beta does not cause neutrophil degranulation but does lead to IL-6, IL-8, and nitrite/nitrate release when used in patients with cancer. Nitrates 91-98 interleukin 1 beta Homo sapiens 0-9 8632501-1 1996 BACKGROUND: Hexogen (cyclonite, RDX) nitrate explosive is an infrequent cause of poisoning. Nitrates 37-44 radixin Homo sapiens 32-35 8569419-3 1996 Thus we studied sex differences in NO-generation by measuring single breath NO-exhalation and plasma levels of nitrate (NO3), the stable endmetabolite of NO. Nitrates 111-118 NBL1, DAN family BMP antagonist Homo sapiens 120-123 8904084-2 1996 Interleukin-1beta stimulated the production of nitrite and nitrate, stable metabolites of NO, in a dose- and time-dependent manner in vascular smooth muscle cells. Nitrates 59-66 interleukin 1 beta Rattus norvegicus 0-17 8741130-2 1996 Recently, it has been reported decreased CSF nitrate levels (oxidation product that provides an indirect estimation of nitric oxide) in Parkinson"s disease patients, assessed with a colorimetric method. Nitrates 45-52 colony stimulating factor 2 Homo sapiens 41-44 8741130-5 1996 They were not influenced significantly by antiparkinsonian drugs in patients, although there was a trend for CSF nitrate levels to be higher in patients treated with levodopa or with dopamine agonists. Nitrates 113-120 colony stimulating factor 2 Homo sapiens 109-112 8628918-11 1996 Several cases of methemoglobinemia have been reported in infants in the United States using water containing nitrate at levels higher than the current maximum contaminant level (MCL) of 45 ppm (mg/liter) nitrate (NO3) or 10 ppm nitrate-nitrogen (nitrate-N), but none at or lower than the MCL. Nitrates 109-116 NBL1, DAN family BMP antagonist Homo sapiens 213-216 8628918-11 1996 Several cases of methemoglobinemia have been reported in infants in the United States using water containing nitrate at levels higher than the current maximum contaminant level (MCL) of 45 ppm (mg/liter) nitrate (NO3) or 10 ppm nitrate-nitrogen (nitrate-N), but none at or lower than the MCL. Nitrates 204-211 NBL1, DAN family BMP antagonist Homo sapiens 213-216 8878363-3 1996 The chemical analysis of fog during 32 episodes of local fog (pH, chloride, nitrate, sulphate, sodium, ammonia, potassium, magnesium, calcium) has shown a greater concentration of pollutants and greater acidity in the smaller particles (2-6 microns) which are able to penetrate the bronchial tree. Nitrates 76-83 zinc finger protein, FOG family member 1 Homo sapiens 25-28 8616217-10 1995 The striking degree of conservation between the macrophage-specific mammalian Nramp and its OsNramp1 plant homologue is discussed with respect to possible implications in the metabolism of nitrate in both organisms. Nitrates 189-196 solute carrier family 11 member 1 Homo sapiens 78-83 7489995-4 1995 Pretreatment of mice with IL-1 resulted in elevated levels of nitrite/nitrate in serum and in enhanced nitric oxide synthase (NOS) activity in liver cells isolated from these animals. Nitrates 70-77 interleukin 1 complex Mus musculus 26-30 7594544-6 1995 Increased levels of nitrate (NO3-) were only detected in serum of resistant C57BL/6 mice at the time of peak parasitemia. Nitrates 20-27 NBL1, DAN family BMP antagonist Mus musculus 29-32 7492033-10 1995 For the Indonesian dry (powdered) milk sample studied the nitrate levels were in the range 10.7-29.5 mg kg-1 NO3-. Nitrates 58-65 NBL1, DAN family BMP antagonist Homo sapiens 109-112 8597057-2 1995 Pretreatment of mice with interleukin-1 beta (IL-1) resulted in elevated levels of nitrite/nitrate in serum and rendered mice insensitive towards TNF toxicity. Nitrates 91-98 interleukin 1 beta Mus musculus 26-44 8597057-2 1995 Pretreatment of mice with interleukin-1 beta (IL-1) resulted in elevated levels of nitrite/nitrate in serum and rendered mice insensitive towards TNF toxicity. Nitrates 91-98 interleukin 1 complex Mus musculus 46-50 8747803-13 1995 N-acetylcysteine inhibits angiotensin converting enzyme and counteracts nitrate-induced stimulation of the renin angiotensin system in vivo. Nitrates 72-79 renin Homo sapiens 107-112 8747803-17 1995 Thus, administration of NAC may change the normal vasodilator profile of nitrates. Nitrates 73-81 synuclein alpha Homo sapiens 24-27 7594598-18 1995 Subcutaneous IL-2 therapy increased urinary nitrate excretion up to eightfold in mice, and appeared to produce a significant survival advantage that was prevented by MLA administration. Nitrates 44-51 interleukin 2 Mus musculus 13-17 8534848-6 1995 They were designated as iNR1 and iNR2, respectively, since both were inducible by nitrate. Nitrates 82-89 inducible nitrate reductase [NADH] 1 Glycine max 24-28 8534848-6 1995 They were designated as iNR1 and iNR2, respectively, since both were inducible by nitrate. Nitrates 82-89 inducible nitrate reductase [NADH] 2 Glycine max 33-37 8534848-16 1995 In northern blots, the steady-state level of iNR1 mRNA was similar for the nr1 mutant and the wild-type parent after 20 to 48 h induction by nitrate. Nitrates 141-148 inducible nitrate reductase [NADH] 1 Glycine max 45-49 8534848-16 1995 In northern blots, the steady-state level of iNR1 mRNA was similar for the nr1 mutant and the wild-type parent after 20 to 48 h induction by nitrate. Nitrates 141-148 LOC100037451 Glycine max 75-78 7545539-10 1995 Oral administration of N-monomethyl-L-arginine, an inhibitor of nitric oxide synthase (NOS), reduced urinary nitrate excretion and also the severity of myositis. Nitrates 109-116 nitric oxide synthase 1, neuronal Mus musculus 64-85 7561687-10 1995 Similarly, 4% of the embryos from pregnant CD1 mice on days 8 and 12 of gestation produced a significant amount of nitrate, which again correlated with the low incidence of resorption observed in these mice. Nitrates 115-122 CD1 antigen complex Mus musculus 43-46 7483050-8 1995 Ongoing treatment with diuretics did not seem to be a risk factor for developing reduced kidney function, whereas significantly more patients on treatment with nitrates, indicating generalised atherosclerosis, developed reduced kidney function during treatment with ACE-inhibitors. Nitrates 160-168 angiotensin I converting enzyme Homo sapiens 266-269 8556991-4 1995 However, LPS combined with either EGF or PDGF caused a significant increase in nitrite/nitrate concentration relative to LPS alone and growth factor alone. Nitrates 87-94 epidermal growth factor like 1 Rattus norvegicus 34-37 8556991-5 1995 The highest level level of nitrite/nitrate concentration was observed with the triple combination of LPS, EGF, and PDGF. Nitrates 35-42 epidermal growth factor like 1 Rattus norvegicus 106-109 7596294-1 1995 The expression of the structural genes nit-3 and nit-6, which encode the nitrate assimilatory enzymes nitrate reductase and nitrite reductase, respectively, is highly regulated by the global-acting NIT2 regulatory protein. Nitrates 73-80 nitrilase family member 2 Homo sapiens 198-202 7674685-7 1995 Nitrates are highly effective antianginal drugs with complex beneficial actions in patients with CAD, but their usefulness is limited by development of tolerance during long-term use. Nitrates 0-8 aconitate decarboxylase 1 Homo sapiens 97-100 7565593-2 1995 To check whether Nii host genes and transgenes (encoding nitrite reductase, the second enzyme of the nitrate assimilation pathway) were also susceptible to silencing, a transgene consisting of the tobacco Nii1 gene with two copies of the enhancer of the 35S promoter cloned 1 kb upstream of the Nii promoter region was introduced into tobacco plants. Nitrates 101-108 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 57-74 7643383-0 1995 Nitrate and nitrite regulation of the Fnr-dependent aeg-46.5 promoter of Escherichia coli K-12 is mediated by competition between homologous response regulators (NarL and NarP) for a common DNA-binding site. Nitrates 0-7 neuronal pentraxin 2 Homo sapiens 171-175 7643383-1 1995 The NarL and NarP proteins are homologous response regulators that function to regulate anaerobic respiratory gene expression in response to nitrate and nitrite in Escherichia coli. Nitrates 141-148 neuronal pentraxin 2 Homo sapiens 13-17 7643383-3 1995 aeg-46.5 operon expression is further induced by the NarP protein in response to nitrate or nitrite and this induction is antagonized by NarL. Nitrates 81-88 neuronal pentraxin 2 Homo sapiens 53-57 7643383-12 1995 Single and double nucleotide substitutions in the -44.5 region reduced or abolished nitrate and nitrite induction of aeg-46.5 operon expression in vivo and prevented the binding of MBP-NarP and MBP-NarL to the control region in vitro. Nitrates 84-91 neuronal pentraxin 2 Homo sapiens 185-189 7643383-12 1995 Single and double nucleotide substitutions in the -44.5 region reduced or abolished nitrate and nitrite induction of aeg-46.5 operon expression in vivo and prevented the binding of MBP-NarP and MBP-NarL to the control region in vitro. Nitrates 84-91 myelin basic protein Homo sapiens 194-197 7643383-13 1995 Presumably, the NarP and NarL proteins compete for the -44.5 binding site to regulate aeg-46.5 operon expression in response to nitrate and nitrite. Nitrates 128-135 neuronal pentraxin 2 Homo sapiens 16-20 7478791-2 1995 The terminal guanidino N-atom of L-arginine is the precursor for NO, which is oxidized to the stable inorganic nitrogen oxides, nitrite (NO2-) and nitrate (NO3-). Nitrates 147-154 NBL1, DAN family BMP antagonist Homo sapiens 156-159 7590863-4 1995 In sera of patients, nitrite plus nitrate levels correlated significantly with neopterin, soluble tumor necrosis factor receptor 55 and 75, and beta 2-microglobulin. Nitrates 34-41 beta-2-microglobulin Homo sapiens 144-164 7565112-8 1995 Therefore, expression of nuo is regulated by O2 and nitrate via ArcA, NarL, FNR and IHF at sites within the -277 region, and by other factors including C4 dicarboxylates at a site between -277 and -899. Nitrates 52-59 arginine deiminase Escherichia coli 64-68 7621816-7 1995 Based on its phenotype and expression pattern as well as its structural similarities to NRAMPs and a nitrate transporter in Aspergillus nidulans, we discuss a possible role for MVL in nitrite/nitrate transport and its implications. Nitrates 101-108 Malvolio Drosophila melanogaster 177-180 7670778-4 1995 The nitrate serum levels correlated closely with CRP and ESR (r = 0.8, P < 0.001, each). Nitrates 4-11 C-reactive protein Homo sapiens 49-52 7539147-5 1995 Paradoxically, constrictions caused by endothelin 1 were decreased in nitrate-tolerant vessels. Nitrates 70-77 endothelin-1 Oryctolagus cuniculus 39-51 7539147-8 1995 We propose that increased autocrine production of endothelin 1 in nitrate tolerance sensitizes vascular smooth muscle to a variety of vasoconstrictors through a protein kinase C-mediated mechanism. Nitrates 66-73 endothelin-1 Oryctolagus cuniculus 50-62 8630818-1 1995 The studies made showed that repeated combined action of chemical factors (pesticides of different chemical groups, Cd and Pb salts, nitrates) in the doses studied resulted in an increase of the lipid peroxidation (LPO) in tissues, accumulation of its end products in biosubstrates, and activation of catalase and peroxidase oxidoreductases in blood of test animals. Nitrates 133-141 catalase Homo sapiens 301-309 7537701-3 1995 Here we demonstrate that injection of endotoxin into rats leads to the expression of an inducible isoform of .NO synthase (iNOS) in the thoracic aorta at 6 h and an increase in the circulating levels of nitrite/nitrate. Nitrates 211-218 nitric oxide synthase 2 Rattus norvegicus 123-127 7536714-2 1995 A combination of interleukin-1 alpha (100 U/mL) and tumor necrosis factor--alpha (5000 U/mL) induced accumulation of nitrite/nitrate, the stable end products of nitric oxide, in culture media within 48 hours. Nitrates 125-132 tumor necrosis factor Rattus norvegicus 17-80 7536714-6 1995 Induction of nitrite/nitrate production by the combination of tumor necrosis factor-alpha and bacterial lipopolysaccharide or that of interleukin-1 alpha and interferon gamma (100 U/mL) was also inhibited by cyclosporin A cotreatment. Nitrates 21-28 tumor necrosis factor Rattus norvegicus 62-89 7536714-6 1995 Induction of nitrite/nitrate production by the combination of tumor necrosis factor-alpha and bacterial lipopolysaccharide or that of interleukin-1 alpha and interferon gamma (100 U/mL) was also inhibited by cyclosporin A cotreatment. Nitrates 21-28 interleukin 1 alpha Rattus norvegicus 134-153 7716247-9 1995 Experiments carried out with detached leaves revealed an influence of light, nitrate, and sucrose on icdh-1 transcript levels and in some cases also on NADP(+)-dependent ICDH activity. Nitrates 77-84 isocitrate dehydrogenase [NADP] Solanum tuberosum 101-107 7716247-10 1995 In darkness, nitrate or sucrose induced icdh-1 mRNA expression. Nitrates 13-20 isocitrate dehydrogenase [NADP] Solanum tuberosum 40-46 12228402-6 1995 In vivo labeling of wheat-leaf PEPC by feeding 32P-labeled orthophosphate showed that PEPC from light plus KNO3 tissue was substantially more phosphorylated than the enzyme in the dark minus-nitrate immunoprecipitates. Nitrates 191-198 phosphoenolpyruvate carboxylase 2 Triticum aestivum 31-35 12228402-6 1995 In vivo labeling of wheat-leaf PEPC by feeding 32P-labeled orthophosphate showed that PEPC from light plus KNO3 tissue was substantially more phosphorylated than the enzyme in the dark minus-nitrate immunoprecipitates. Nitrates 191-198 phosphoenolpyruvate carboxylase 2 Triticum aestivum 86-90 7919993-7 1994 At the amino acid level, the Arabidopsis plant peptide transporter shows 24.6, 28.5, and 45.2% identity to the Arabidopsis nitrate-inducible nitrate transporter (CHL1), the rabbit small intestine oligopeptide transporter (PepT1), and the yeast peptide transporter (Ptr2p), respectively, but little identity to other proteins known to be involved in peptide transport. Nitrates 123-130 nitrate transporter 1.1 Arabidopsis thaliana 162-166 7810695-6 1994 Activation of renin secretion by isethionate and acetate was blunted with 100 pmol/l angiotensin II (ANG II), whereas tenfold higher concentrations of ANG II were required to attenuate the effect of nitrate ions. Nitrates 199-206 renin Rattus norvegicus 14-19 7810695-6 1994 Activation of renin secretion by isethionate and acetate was blunted with 100 pmol/l angiotensin II (ANG II), whereas tenfold higher concentrations of ANG II were required to attenuate the effect of nitrate ions. Nitrates 199-206 angiotensinogen Rattus norvegicus 151-157 7810695-7 1994 The amount of renin released in the presence of nitrate was fully additive to RSR values obtained with maximally effective doses of isoproterenol. Nitrates 48-55 renin Rattus norvegicus 14-19 7810695-9 1994 The stimulatory influence of membrane-permeable nitrate anions appears to involve additional pathways and is mediated by a decreased calcium sensitivity of the renin secretory process rather than resulting from an adenosine 3",5"-cyclic monophosphate-dependent action. Nitrates 48-55 renin Rattus norvegicus 160-165 7743368-2 1994 In this pilot study, we wanted to know if the serum values of nitrite/nitrate (NO2/NO3), the stable endproducts of NO biosynthesis, are elevated in patients with septic shock. Nitrates 70-77 NBL1, DAN family BMP antagonist Homo sapiens 83-86 24306501-7 1994 Feeding nitrate to excised leaves of nitrogen deficient plants enhanced the degree of light activation of PEP carboxylase in the C4 species maize, but had little or no effect in the C3 species wheat. Nitrates 8-15 phosphoenolpyruvate carboxylase 2 Zea mays 106-109 7927208-6 1994 Polyclonal rabbit anti-mouse anti-tumor necrosis factor-alpha reduced in vivo tumor necrosis factor-alpha levels (1 hr, 7,332 +/- 1,492 U tumor necrosis factor-alpha per milliliter) and reduced nitric oxide synthesis as measured by plasma nitrite and nitrate (352 +/- 69 mumol/L). Nitrates 251-258 tumor necrosis factor Mus musculus 34-61 7539338-10 1995 Using previously published data, we developed a pharmacokinetic-pharmacodynamic model that relates the production of TNF in response to administration of FAA, the enhancement of NOS activity in response to TNF, and the elevation of plasma nitrate in response to NO production. Nitrates 239-246 tumor necrosis factor Mus musculus 117-120 8839229-13 1995 The development of ITF 296 as a new orally active nitrate is supported by its pharmacokinetic profile in rats and dogs. Nitrates 50-57 trefoil factor 3 Rattus norvegicus 19-22 7523382-3 1994 The NO metabolites nitrite and nitrate rose > 10-fold in medium from stimulated versus unstimulated cells over 24 h. Concomitant with elevated nitrogen oxides, Egr-1 mRNA levels declined to 80% below unstimulated cells at 24 h. This decline was blocked by an inhibitor of NO production, NG-monomethyl-L-arginine. Nitrates 31-38 early growth response 1 Rattus norvegicus 163-168 7991680-1 1994 Nitrate reductase (NR) is the first enzyme in nitrate assimilation, a critical process for plant survival. Nitrates 46-53 nitrate reductase 1 Arabidopsis thaliana 0-17 7991680-1 1994 Nitrate reductase (NR) is the first enzyme in nitrate assimilation, a critical process for plant survival. Nitrates 46-53 nitrate reductase 1 Arabidopsis thaliana 19-21 7991680-4 1994 We are interested in understanding the mechanism of nitrate induction of higher plant NR genes. Nitrates 52-59 nitrate reductase 1 Arabidopsis thaliana 86-88 7991680-5 1994 Here we describe promoter analyses of the 5" flanking regions of the Arabidopsis NR genes, NR1 and NR2, with respect to nitrate induction of gene expression. Nitrates 120-127 nitrate reductase 1 Arabidopsis thaliana 81-83 7991680-5 1994 Here we describe promoter analyses of the 5" flanking regions of the Arabidopsis NR genes, NR1 and NR2, with respect to nitrate induction of gene expression. Nitrates 120-127 nitrate reductase 1 Arabidopsis thaliana 91-94 7991680-5 1994 Here we describe promoter analyses of the 5" flanking regions of the Arabidopsis NR genes, NR1 and NR2, with respect to nitrate induction of gene expression. Nitrates 120-127 nitrate reductase 2 Arabidopsis thaliana 99-102 7991680-8 1994 Deletion analyses of these regions show that 238- and 188-bp 5" flanking regions of the NR1 and NR2, respectively, contain sequences responsive to nitrate induction. Nitrates 147-154 nitrate reductase 1 Arabidopsis thaliana 88-91 7991680-8 1994 Deletion analyses of these regions show that 238- and 188-bp 5" flanking regions of the NR1 and NR2, respectively, contain sequences responsive to nitrate induction. Nitrates 147-154 nitrate reductase 2 Arabidopsis thaliana 96-99 7812715-2 1994 The first step of the pathway, the reduction of nitrate to nitrite, is catalyzed by nitrate reductase, a multi-redox cofactor enzyme which belongs to the class of flavoprotein pyridine nucleotide cytochrome reductases. Nitrates 48-55 nitrate reductase [NADH] 1 Zea mays 84-101 7919993-7 1994 At the amino acid level, the Arabidopsis plant peptide transporter shows 24.6, 28.5, and 45.2% identity to the Arabidopsis nitrate-inducible nitrate transporter (CHL1), the rabbit small intestine oligopeptide transporter (PepT1), and the yeast peptide transporter (Ptr2p), respectively, but little identity to other proteins known to be involved in peptide transport. Nitrates 123-130 solute carrier family 15 member 1 Oryctolagus cuniculus 222-227 7919993-7 1994 At the amino acid level, the Arabidopsis plant peptide transporter shows 24.6, 28.5, and 45.2% identity to the Arabidopsis nitrate-inducible nitrate transporter (CHL1), the rabbit small intestine oligopeptide transporter (PepT1), and the yeast peptide transporter (Ptr2p), respectively, but little identity to other proteins known to be involved in peptide transport. Nitrates 123-130 Ptr2p Saccharomyces cerevisiae S288C 265-270 7867440-3 1994 However, when captopril (CPT, 12.5-25mg, 3 times daily) was combined with nitrates, the clinical effects were enhanced and maintained throughout the study, along with a decrease in the level of AII and body weight. Nitrates 74-82 angiotensinogen Homo sapiens 194-197 8033999-4 1994 In addition to members of the AAP gene family, an integral membrane protein (NTR1) that shows significant similarities to the low affinity nitrate transporter from Arabidpsis and to peptide transporters from yeast and rabbit was identified. Nitrates 139-146 mRNA splicing protein SPP382 Saccharomyces cerevisiae S288C 77-81 8066882-3 1994 The nitrates are inactive prodrugs, and their vascular effects depend on metabolic conversion to vasoactive intermediates like nitric oxide and/or nitrosothiols with subsequent stimulation of guanylate cyclase causing increased formation of cyclic GMP. Nitrates 4-12 5'-nucleotidase, cytosolic II Homo sapiens 248-251 8087822-3 1994 However, nitrates also exhibit platelet-inhibiting properties, mediated by the same cellular mechanisms operating on smooth muscle cells, i.e., via stimulation of guanylate cyclase and subsequent increase in cytosolic levels of cyclic GMP. Nitrates 9-17 5'-nucleotidase, cytosolic II Homo sapiens 235-238 8180640-8 1994 CONCLUSIONS: A controlled clinical trial is needed to clarify how consuming high-nitrate foods correlates with methemoglobin levels in infants younger than 6 months. Nitrates 81-88 hemoglobin subunit gamma 2 Homo sapiens 111-124 8209223-5 1994 Nitrate levels of > 45 mg l-1 were observed in 8% of the well samples in 1989 and 5% of them showed the presence of both elevated levels of nitrate and faecal coliforms. Nitrates 0-7 immunoglobulin kappa variable 1-16 Homo sapiens 29-32 7914830-1 1994 As a result of recent advances in our understanding of the role of nitric oxide and endothelial-derived relaxing factor (EDRF) in vascular control, physicians now have the potential to overcome the loss of EDRF effect by administering nitrates. Nitrates 235-243 alpha hemoglobin stabilizing protein Homo sapiens 84-119 7914830-1 1994 As a result of recent advances in our understanding of the role of nitric oxide and endothelial-derived relaxing factor (EDRF) in vascular control, physicians now have the potential to overcome the loss of EDRF effect by administering nitrates. Nitrates 235-243 alpha hemoglobin stabilizing protein Homo sapiens 121-125 7914830-1 1994 As a result of recent advances in our understanding of the role of nitric oxide and endothelial-derived relaxing factor (EDRF) in vascular control, physicians now have the potential to overcome the loss of EDRF effect by administering nitrates. Nitrates 235-243 alpha hemoglobin stabilizing protein Homo sapiens 206-210 8132465-7 1994 Results presented here indicate that the increase of sdh and lct expression by nitrate depended on its chemical reduction, which in turn diminished the ArcA-P pool. Nitrates 79-86 arginine deiminase Escherichia coli 152-156 8180624-1 1994 The Chlamydomonas reinhardtii nar-2, nar-3, and nar-4 genes, which are within a nitrate-regulated gene cluster containing the nitrate reductase structural gene nit-1, have been related to nitrate transport. Nitrates 80-87 uncharacterized protein Chlamydomonas reinhardtii 160-165 8180624-1 1994 The Chlamydomonas reinhardtii nar-2, nar-3, and nar-4 genes, which are within a nitrate-regulated gene cluster containing the nitrate reductase structural gene nit-1, have been related to nitrate transport. Nitrates 126-133 uncharacterized protein Chlamydomonas reinhardtii 48-53 8180624-1 1994 The Chlamydomonas reinhardtii nar-2, nar-3, and nar-4 genes, which are within a nitrate-regulated gene cluster containing the nitrate reductase structural gene nit-1, have been related to nitrate transport. Nitrates 126-133 uncharacterized protein Chlamydomonas reinhardtii 160-165 8180624-3 1994 Their nitrate non-utilizing phenotype has been directly complemented by transformation using the pCO-5 plasmid which carries the nar-2, nar-3, and nar-4 clustered genes. Nitrates 6-13 uncharacterized protein Chlamydomonas reinhardtii 147-152 8180624-5 1994 Complementation of the nitrate non-utilizing phenotype of the constructed strains was also achieved by co-transformation with plasmids containing nar-2 and nar-3 genes or nar-2 and nar-4, but not with single plasmids containing each individual gene. Nitrates 23-30 uncharacterized protein Chlamydomonas reinhardtii 181-186 7508220-5 1994 Hepatocyte iNOS messenger RNA (mRNA) levels were correlated with iNOS activity and circulating plasma nitrite and nitrate levels. Nitrates 114-121 nitric oxide synthase 2 Rattus norvegicus 11-15 7507509-3 1994 MRL-lpr/lpr mice excreted more urinary nitrite/nitrate (an in vivo marker of nitric oxide production) than did mice of normal strains and MRL-(+/+) and B6-lpr/lpr congenic strains. Nitrates 47-54 Fas (TNF receptor superfamily member 6) Mus musculus 4-7 7507509-3 1994 MRL-lpr/lpr mice excreted more urinary nitrite/nitrate (an in vivo marker of nitric oxide production) than did mice of normal strains and MRL-(+/+) and B6-lpr/lpr congenic strains. Nitrates 47-54 Fas (TNF receptor superfamily member 6) Mus musculus 8-11 7507509-3 1994 MRL-lpr/lpr mice excreted more urinary nitrite/nitrate (an in vivo marker of nitric oxide production) than did mice of normal strains and MRL-(+/+) and B6-lpr/lpr congenic strains. Nitrates 47-54 Fas (TNF receptor superfamily member 6) Mus musculus 8-11 7507509-3 1994 MRL-lpr/lpr mice excreted more urinary nitrite/nitrate (an in vivo marker of nitric oxide production) than did mice of normal strains and MRL-(+/+) and B6-lpr/lpr congenic strains. Nitrates 47-54 Fas (TNF receptor superfamily member 6) Mus musculus 8-11 8185875-6 1994 The principle component of the coating is nitrite ion, which in the presence of ozone is oxidized to nitrate ion on the filter medium (NO2- + O3 produces NO3- + O2). Nitrates 101-108 NBL1, DAN family BMP antagonist Homo sapiens 154-157 7508388-2 1994 Nitric oxide (NO) reductase is an integral membrane component of the anaerobic respiratory chain of Pseudomonas stutzeri that transforms nitrate to dinitrogen (denitrification). Nitrates 137-144 cbb3-type cytochrome c oxidase subunit I Pseudomonas stutzeri 0-27 7523451-3 1994 Treatment with IL-1 beta resulted in a marked increase in media nitrite and nitrate accumulation, morphological alterations, and increased release of lactate dehydrogenase (LDH) into media. Nitrates 76-83 interleukin 1 beta Rattus norvegicus 15-24 8182055-1 1994 Nitrate reductase (NR), the first enzyme in the nitrate assimilation pathway, is regulated post-transcriptionally in response to light and CO2. Nitrates 48-55 nitrate reductase 1 Arabidopsis thaliana 0-17 8182055-1 1994 Nitrate reductase (NR), the first enzyme in the nitrate assimilation pathway, is regulated post-transcriptionally in response to light and CO2. Nitrates 48-55 nitrate reductase 1 Arabidopsis thaliana 19-21 8184893-7 1994 Similarly, iodide and nitrate stimulated renin release. Nitrates 22-29 renin Rattus norvegicus 41-46 8113156-6 1994 Both nitrates and nifedipine induced a significant decrease in DR1/3 (indicating an increase in left ventricular ejection flow) in relation to a reduction of the reflected pressure wave. Nitrates 5-13 down-regulator of transcription 1 Homo sapiens 63-68 16349084-12 1993 Ectocellular aminopeptidase may be common in marine synechococci and play roles in their nitrogen nutrition, particularly in low-nitrate and low-light environments. Nitrates 129-136 carboxypeptidase Q Homo sapiens 13-27 8180624-1 1994 The Chlamydomonas reinhardtii nar-2, nar-3, and nar-4 genes, which are within a nitrate-regulated gene cluster containing the nitrate reductase structural gene nit-1, have been related to nitrate transport. Nitrates 80-87 uncharacterized protein Chlamydomonas reinhardtii 48-53 8111016-2 1994 In ammonium-grown wild-type cells, nit-1 (nitrate reductase, NR), nar-1, nar-2 and nar-3 (nitrate transporter) genes showed very similar kinetics of expression when transferred to nitrate medium. Nitrates 42-49 uncharacterized protein Chlamydomonas reinhardtii 35-40 8111016-5 1994 In contrast to the other nar transcripts, that nar-4, a gene sharing similar sequences with nar-3, accumulated in small amounts in wild-type cells, and only increased after a long nitrate induction period. Nitrates 180-187 uncharacterized protein Chlamydomonas reinhardtii 47-52 8286141-3 1993 In spite of the highly favourable results regarding mortality shown by the latest studies with ACE inhibitors, the nitrates still occupy an essential place in the therapy of patients with heart failure, since they have the advantage of a much faster onset of action and are more effective in relieving symptoms than ACE inhibitors. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 95-98 8225220-6 1993 High serum nitrite/nitrate levels were associated with high plasma renin activity, high aldosterone and antidiuretic hormone levels and low urinary excretion of sodium. Nitrates 19-26 renin Homo sapiens 67-72 7509009-2 1993 The combination of interferon-gamma (100 U/ml) and tumor necrosis factor-alpha (5000 U/ml) evoked a time-dependent increase in nitric oxide synthase mRNA and nitrite/nitrate production, both of which were inhibited by dexamethasone. Nitrates 166-173 tumor necrosis factor Rattus norvegicus 19-78 8286141-3 1993 In spite of the highly favourable results regarding mortality shown by the latest studies with ACE inhibitors, the nitrates still occupy an essential place in the therapy of patients with heart failure, since they have the advantage of a much faster onset of action and are more effective in relieving symptoms than ACE inhibitors. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 316-319 8248688-4 1993 In parallel with the discovery of the endothelium-derived relaxing factor (EDRF) and its biochemical identification as nitric oxide (NO), it became clear that organic nitrates act via the release of NO in the vascular wall and thus by using metabolic pathways identical to those of endogenous EDRF. Nitrates 167-175 alpha hemoglobin stabilizing protein Homo sapiens 75-79 8248688-4 1993 In parallel with the discovery of the endothelium-derived relaxing factor (EDRF) and its biochemical identification as nitric oxide (NO), it became clear that organic nitrates act via the release of NO in the vascular wall and thus by using metabolic pathways identical to those of endogenous EDRF. Nitrates 167-175 alpha hemoglobin stabilizing protein Homo sapiens 293-297 8399219-6 1993 However, upon addition of MgADP plus creatine and nitrate to induce a transition-state analogue complex of the enzyme, native Mib-CK dissociated much more readily into dimers than proteinase K-digested Mib-CK. Nitrates 50-57 creatine kinase, mitochondrial 2 Gallus gallus 126-132 8399219-6 1993 However, upon addition of MgADP plus creatine and nitrate to induce a transition-state analogue complex of the enzyme, native Mib-CK dissociated much more readily into dimers than proteinase K-digested Mib-CK. Nitrates 50-57 creatine kinase, mitochondrial 2 Gallus gallus 202-208 8134178-1 1993 In a rat model of fatal infection caused by Pseudomonas aeruginosa, the circulating level of nitrite/nitrate (NO2-/NO3-), a good indicator for nitric oxide production, was remarkably increased after elevation of circulatory tumor necrosis factor (TNF). Nitrates 101-108 tumor necrosis factor-like Rattus norvegicus 224-245 8413188-1 1993 Three overlapping clones covering a Chlamydomonas reinhardtii genomic region of about 32 kb appear to contain five genes potentially involved in nitrate assimilation in addition to the nitrate reductase structural locus nit-1. Nitrates 145-152 uncharacterized protein Chlamydomonas reinhardtii 185-202 8413188-1 1993 Three overlapping clones covering a Chlamydomonas reinhardtii genomic region of about 32 kb appear to contain five genes potentially involved in nitrate assimilation in addition to the nitrate reductase structural locus nit-1. Nitrates 145-152 uncharacterized protein Chlamydomonas reinhardtii 220-225 8413188-2 1993 These new loci produced transcripts of 2.8, 2.2, 1.8 and 1.7 kb in nitrate-induced wild-type cells that, like the 3.4 kb transcript of nit-1, were undetectable in cells grown in ammonium. Nitrates 67-74 nitrilase 1 Mus musculus 135-140 8413188-3 1993 In addition, in a mutant defective at the regulatory locus, nit-2 for nitrate assimilation, which does not express the nit-1 gene transcript, accumulation of the four other transcripts was also blocked. Nitrates 70-77 uncharacterized protein Chlamydomonas reinhardtii 60-65 8134178-1 1993 In a rat model of fatal infection caused by Pseudomonas aeruginosa, the circulating level of nitrite/nitrate (NO2-/NO3-), a good indicator for nitric oxide production, was remarkably increased after elevation of circulatory tumor necrosis factor (TNF). Nitrates 101-108 tumor necrosis factor-like Rattus norvegicus 247-250 8368322-4 1993 Nitrite/nitrate accumulation was maximal at 72 h, with most of the increase occurring from 48 to 72 h. Maximal nitrite/nitrate production was observed with triple combinations with the combination of LPS, IL-1, and TNF giving the highest concentration (137.4 +/- 2.8 microM). Nitrates 8-15 tumor necrosis factor-like Rattus norvegicus 215-218 8368322-4 1993 Nitrite/nitrate accumulation was maximal at 72 h, with most of the increase occurring from 48 to 72 h. Maximal nitrite/nitrate production was observed with triple combinations with the combination of LPS, IL-1, and TNF giving the highest concentration (137.4 +/- 2.8 microM). Nitrates 119-126 tumor necrosis factor-like Rattus norvegicus 215-218 8391783-2 1993 Nitrate binds to the active site of hexokinase when MnIIADP and a sugar substrate or analogue are present. Nitrates 0-7 hexokinase 1 Homo sapiens 36-46 8391401-2 1993 BACKGROUND: The present study was designed to investigate the intracellular production of cyclic GMP (cGMP) in platelets in response to nitroglycerin and to determine the potential clinical value of platelet cGMP as an indicator of the effects of nitroglycerin and nitrate tolerance. Nitrates 265-272 5'-nucleotidase, cytosolic II Homo sapiens 97-100 8391783-8 1993 These results suggest that nitrate-stabilized, dead-end complexes of hexokinase may be useful in stabilizing the closed conformation of this "hinge-bending" enzyme for crystallographic experiments. Nitrates 27-34 hexokinase 1 Homo sapiens 69-79 8394263-1 1993 Genetic evidence suggests that the NIT2 gene of Chlamydomonas reinhardtii encodes a positive regulator of the nitrate-assimilation pathway. Nitrates 110-117 uncharacterized protein Chlamydomonas reinhardtii 35-39 8394263-9 1993 These results suggest that repression of the NIT2 gene may mediate metabolite repression of the nitrate assimilation pathway in Chlamydomonas. Nitrates 96-103 uncharacterized protein Chlamydomonas reinhardtii 45-49 8435934-7 1993 ACE inhibitors may reduce tolerance to nitrates, reduce angina in some but not all studies, and limit smooth muscle cell proliferation (and perhaps restenosis) induced by experimental balloon angioplasty. Nitrates 39-47 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Mus musculus 0-3 8389858-1 1993 Nitrate tolerance has been explained by 1) a direct loss of pharmacological effect due to reduced bioconversion and 2) an indirect effect due to activation of the renin/angiotensin system and counter-regulatory vasoconstriction. Nitrates 0-7 renin Rattus norvegicus 163-168 8504586-6 1993 In a canine experimental model of acute regional myocardial necrosis, hypertrophy and dilatation appear to have a different time course, and both may be attenuated by pharmacologic intervention with either an angiotensin-converting enzyme (ACE) inhibitor or a nitrate. Nitrates 260-267 angiotensin I converting enzyme Canis lupus familiaris 209-238 8447474-2 1993 Incubation of vascular smooth muscle cells with IL-1 beta resulted in significant accumulation of nitrite and nitrate in the culture media. Nitrates 110-117 interleukin 1 beta Homo sapiens 48-57 8447474-3 1993 Plasmin, either added exogenously or generated by the reaction of tissue plasminogen activator with plasminogen, potentiated the IL-1 beta-mediated release of nitrite and nitrate from smooth muscle cells in a concentration-dependent manner, without affecting the production of nitrite and nitrate from cells untreated with IL-1 beta. Nitrates 171-178 plasminogen Homo sapiens 0-7 8447474-3 1993 Plasmin, either added exogenously or generated by the reaction of tissue plasminogen activator with plasminogen, potentiated the IL-1 beta-mediated release of nitrite and nitrate from smooth muscle cells in a concentration-dependent manner, without affecting the production of nitrite and nitrate from cells untreated with IL-1 beta. Nitrates 171-178 interleukin 1 beta Homo sapiens 129-138 8447474-3 1993 Plasmin, either added exogenously or generated by the reaction of tissue plasminogen activator with plasminogen, potentiated the IL-1 beta-mediated release of nitrite and nitrate from smooth muscle cells in a concentration-dependent manner, without affecting the production of nitrite and nitrate from cells untreated with IL-1 beta. Nitrates 289-296 plasminogen Homo sapiens 0-7 8447474-3 1993 Plasmin, either added exogenously or generated by the reaction of tissue plasminogen activator with plasminogen, potentiated the IL-1 beta-mediated release of nitrite and nitrate from smooth muscle cells in a concentration-dependent manner, without affecting the production of nitrite and nitrate from cells untreated with IL-1 beta. Nitrates 289-296 interleukin 1 beta Homo sapiens 129-138 8510658-4 1993 Plants in which the NIA2 gene has been deleted retain only 10% of the wild-type shoot NR activity and grow normally with nitrate as the sole nitrogen source. Nitrates 121-128 nitrate reductase 2 Arabidopsis thaliana 20-24 8510658-6 1993 nia1, nia2 double mutants have only 0.5% of wild-type shoot NR activity and display very poor growth on media with nitrate as the only form of nitrogen. Nitrates 115-122 nitrate reductase 1 Arabidopsis thaliana 0-4 8510658-6 1993 nia1, nia2 double mutants have only 0.5% of wild-type shoot NR activity and display very poor growth on media with nitrate as the only form of nitrogen. Nitrates 115-122 nitrate reductase 2 Arabidopsis thaliana 6-10 8510658-8 1993 These results show that the NIA1 gene encodes a functional NR protein that contributes to the assimilation of nitrate in Arabidopsis. Nitrates 110-117 nitrate reductase 1 Arabidopsis thaliana 28-32 8510658-8 1993 These results show that the NIA1 gene encodes a functional NR protein that contributes to the assimilation of nitrate in Arabidopsis. Nitrates 110-117 nitrate reductase 1 Arabidopsis thaliana 59-61 7682068-3 1993 Inducible nitric oxide synthase (iNOS) activity was determined by measuring the stable nitrogen oxide end products of L-arginine oxidation: nitrite (NO2-) and nitrate (NO3-). Nitrates 159-166 nitric oxide synthase 2 Rattus norvegicus 0-31 7682068-3 1993 Inducible nitric oxide synthase (iNOS) activity was determined by measuring the stable nitrogen oxide end products of L-arginine oxidation: nitrite (NO2-) and nitrate (NO3-). Nitrates 159-166 nitric oxide synthase 2 Rattus norvegicus 33-37 8453665-2 1993 The CHL1 gene of Arabidopsis, which when mutated confers resistance to the herbicide chlorate and a decrease in nitrate uptake, was isolated and found to encode a protein with 12 putative membrane-spanning segments. Nitrates 112-119 nitrate transporter 1.1 Arabidopsis thaliana 4-8 8453665-3 1993 Injection of CHL1 mRNA into Xenopus oocytes produces a nitrate- and pH-dependent membrane depolarization, inward current, and nitrate uptake. Nitrates 55-62 DEAD/H-box helicase 11 L homeolog Xenopus laevis 13-17 8453665-3 1993 Injection of CHL1 mRNA into Xenopus oocytes produces a nitrate- and pH-dependent membrane depolarization, inward current, and nitrate uptake. Nitrates 126-133 DEAD/H-box helicase 11 L homeolog Xenopus laevis 13-17 8453665-5 1993 CHL1 mRNA is found predominantly in roots and displays nitrate- and pH-dependent regulation. Nitrates 55-62 nitrate transporter 1.1 Arabidopsis thaliana 0-4 8483458-4 1993 Some of these nit-1 or nit-2 mutants were also defective in pathways not directly related to nitrate assimilation, such as those of amino acids and purines. Nitrates 93-100 uncharacterized protein Chlamydomonas reinhardtii 14-19 8483458-4 1993 Some of these nit-1 or nit-2 mutants were also defective in pathways not directly related to nitrate assimilation, such as those of amino acids and purines. Nitrates 93-100 uncharacterized protein Chlamydomonas reinhardtii 23-28 8499119-3 1993 In spite of the highly favourable results regarding mortality shown by the latest studies with ACE inhibitors, the nitrates still occupy an essential place in the therapy of patients with heart failure, since they have the advantage of a much faster onset of action and are more effective in relieving symptoms than ACE inhibitors. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 95-98 8499119-3 1993 In spite of the highly favourable results regarding mortality shown by the latest studies with ACE inhibitors, the nitrates still occupy an essential place in the therapy of patients with heart failure, since they have the advantage of a much faster onset of action and are more effective in relieving symptoms than ACE inhibitors. Nitrates 115-123 angiotensin I converting enzyme Homo sapiens 316-319 8278505-2 1993 A possible physiological role of this enzyme could be in the turnover of nitrate reductase (NR) and, as such, it could be of great importance in regulating the assimilation of nitrate. Nitrates 73-80 nitrate reductase [NADH] 1 Zea mays 92-94 8440160-11 1993 The effect of captopril in nitrate tolerance is apparently due to an addition of the anti-ischaemic action of the ACE inhibitor (31%) and the residual effect of the nitrate (26%). Nitrates 27-34 angiotensin I converting enzyme Homo sapiens 114-117 8423095-3 1993 Intraperitoneal injection of mice with BCG increased urinary nitrate (NO3-) excretion coincident with development of activated macrophages capable of secreting nitrogen oxides and inhibiting F. tularensis growth in vitro. Nitrates 61-68 NBL1, DAN family BMP antagonist Mus musculus 70-73 8282225-1 1993 The production of nitrate (NO3-) and nitrite (NO2-) from macrophage-derived NO was studied using EPR and spin trapping. Nitrates 18-25 NBL1, DAN family BMP antagonist Homo sapiens 27-30 8437565-5 1993 The accumulation of both leaf and root NiR mRNAs was induced by nitrate and repressed by nitrate- or ammonium-derived metabolites. Nitrates 64-71 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 39-42 8437565-5 1993 The accumulation of both leaf and root NiR mRNAs was induced by nitrate and repressed by nitrate- or ammonium-derived metabolites. Nitrates 89-96 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 39-42 8437574-7 1993 Nitrite reductase activity, measured with dithionite-reduced methyl viologen as electron donor, of the nitrate-treated homozygous nir1 mutant was much reduced but NADH-nitrate reductase activity was elevated compared to wild-type plants. Nitrates 103-110 PITPNM family member 3 Homo sapiens 130-134 8419922-1 1993 Urinary nitrate (NO3) is the stable end product of nitric oxide, which is formed, in turn, from a guanidino nitrogen of arginine. Nitrates 8-15 NBL1, DAN family BMP antagonist Homo sapiens 17-20 1336460-1 1992 The structures of human carbonic-anhydrase-II complexes with the anionic inhibitors hydrogen sulphide (HS-) and nitrate (NO3-) have been determined by X-ray diffraction at 0.19-nm resolution from crystals soaked at pH 7.8 and 6.0, respectively. Nitrates 112-119 carbonic anhydrase 2 Homo sapiens 24-45 1336460-1 1992 The structures of human carbonic-anhydrase-II complexes with the anionic inhibitors hydrogen sulphide (HS-) and nitrate (NO3-) have been determined by X-ray diffraction at 0.19-nm resolution from crystals soaked at pH 7.8 and 6.0, respectively. Nitrates 112-119 NBL1, DAN family BMP antagonist Homo sapiens 121-124 1442583-6 1992 The results of this study demonstrate a preserved vasodilatory effect of organic nitrates in patients already treated with ACE inhibitors. Nitrates 81-89 angiotensin I converting enzyme Homo sapiens 123-126 16653241-3 1992 Addition of methionine sulfoximine (MSX), a specific inhibitor of glutamine synthetase, inhibited the nitrate-dependent increase of PEPC and CA mRNA but did not affect the glutamine-dependent increase of PEPC and CA mRNA levels. Nitrates 102-109 MLO-like protein 4 Zea mays 132-136 16653241-3 1992 Addition of methionine sulfoximine (MSX), a specific inhibitor of glutamine synthetase, inhibited the nitrate-dependent increase of PEPC and CA mRNA but did not affect the glutamine-dependent increase of PEPC and CA mRNA levels. Nitrates 102-109 carbonic anhydrase Zea mays 141-143 16653241-3 1992 Addition of methionine sulfoximine (MSX), a specific inhibitor of glutamine synthetase, inhibited the nitrate-dependent increase of PEPC and CA mRNA but did not affect the glutamine-dependent increase of PEPC and CA mRNA levels. Nitrates 102-109 MLO-like protein 4 Zea mays 204-208 1442583-7 1992 Nitrates mediated improvement in right and left ventricular filling pressures, and reduction of pulmonary hypertension demonstrates a rationale for the use of these therapeutic methods in combination and suggest the need for long-term evaluation of the effect of nitrate therapy in patients with chronic CHF already treated with ACE inhibitors. Nitrates 0-8 angiotensin I converting enzyme Homo sapiens 329-332 1530430-6 1992 The interactions of nitrate derivatives with molecules used as platelet inhibitors, such as aspirin, require further study as do interactions with heparin (possible induction of resistance by a qualitative anti-thrombin III deficiency) and thrombolytics (increased clearance of tissue type plasminogen activator). Nitrates 20-27 plasminogen activator, tissue type Homo sapiens 278-311 1375656-5 1992 Plasma levels of nitrate (NO3-), the stable end metabolic product of .N = O synthesis, were measured before and at the end of IL-2 treatment cycles. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 26-29 1533499-3 1992 The enzyme was inhibited by the vacuolar ATPase inhibitors nitrate and N-ethylmaleimide; 4-chloro-7-nitrobenzofurazan (NBD-Cl) was also inhibitory. Nitrates 59-66 tRNA(Met) cytidine acetyltransferase TmcA Saccharolobus solfataricus 41-47 1632143-4 1992 Calcium channel blockers (nifedipine and verapamil) or nitrates (isosorbide dinitrate) decrease LES pressure but do little to the clinical symptomatology of patients with achalasia; however such drug therapy may be tried as an adjunct in patients who remain symptomatic after pneumatic dilatations or myotomy. Nitrates 55-63 fucosyltransferase 3 (Lewis blood group) Homo sapiens 96-99 1534867-2 1992 Hundreds of chlorate-resistant mutants have been identified in plants, and almost all have been found to be defective in nitrate reduction due to mutations in either nitrate reductase (NR) structural genes or genes required for the synthesis of the NR cofactor molybdenum-pterin (MoCo). Nitrates 121-128 nitrate reductase 1 Arabidopsis thaliana 166-183 1534867-2 1992 Hundreds of chlorate-resistant mutants have been identified in plants, and almost all have been found to be defective in nitrate reduction due to mutations in either nitrate reductase (NR) structural genes or genes required for the synthesis of the NR cofactor molybdenum-pterin (MoCo). Nitrates 121-128 nitrate reductase 1 Arabidopsis thaliana 185-187 1534867-2 1992 Hundreds of chlorate-resistant mutants have been identified in plants, and almost all have been found to be defective in nitrate reduction due to mutations in either nitrate reductase (NR) structural genes or genes required for the synthesis of the NR cofactor molybdenum-pterin (MoCo). Nitrates 121-128 nitrate reductase 1 Arabidopsis thaliana 249-251 1314486-3 1992 A combination of lipopolysaccharide (LPS), interferon-gamma, tumor necrosis factor, and interleukin-1 stimulates the biosynthesis of large quantities of nitrite and nitrate (NO2- + NO3-). Nitrates 165-172 interferon gamma Rattus norvegicus 43-59 16653041-1 1992 Effects of NO(2) (-), ClO(3) (-), and ClO(2) (-) on the induction of nitrate transport and nitrate reductase activity (NRA) as well as their effects on NO(3) (-) influx into roots of intact barley (Hordeum vulgare cv Klondike) seedlings were investigated. Nitrates 69-76 Clo2 Hordeum vulgare 38-44 1500182-0 1992 In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: possible roles in malaria. Nitrates 33-40 tumor necrosis factor Mus musculus 44-65 16652938-6 1992 Simultaneous addition of high nitrate and zeatin to leaves detached from N-deficient maize plants caused a large and rapid increase in PEPC and CA mRNA levels. Nitrates 30-37 MLO-like protein 4 Zea mays 135-139 16652938-6 1992 Simultaneous addition of high nitrate and zeatin to leaves detached from N-deficient maize plants caused a large and rapid increase in PEPC and CA mRNA levels. Nitrates 30-37 carbonic anhydrase Zea mays 144-146 16653003-4 1992 The addition of nitrate to wheat seedlings (Triticum aestivum) grown in the absence of exogenous nitrogen has a dramatic, if transient, impact on sucrose formation and on the activities of sucrose phosphate synthase (which is inactivated) and phosphoenolpyruvate carboxylase (which is activated). Nitrates 16-23 phosphoenolpyruvate carboxylase 2 Triticum aestivum 243-274 16669032-5 1992 Regulation of the phosphorylation of SPS may provide a general mechanism whereby sucrose formation is coordinated with the rate of photosynthesis and the rate of nitrate assimilation. Nitrates 162-169 sucrose-phosphate synthase Zea mays 37-40 1621630-5 1992 Infants are particularly susceptible to nitrate poisoning because fetal hemoglobin is more readily oxidized to methemoglobin. Nitrates 40-47 hemoglobin subunit gamma 2 Homo sapiens 111-124 1377225-5 1992 Increased levels of nitrite (NO2-) and nitrate (NO3-) in culture supernatants were associated with NADPH-dependent NOS activity in the cell lysates. Nitrates 39-46 NBL1, DAN family BMP antagonist Homo sapiens 48-51 1352550-0 1992 Cytochrome P-450 mediates bioactivation of organic nitrates. Nitrates 51-59 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 0-16 1352550-10 1992 These findings suggest that in intact cells bioactivation of, i.e., nitric oxide formation from organic nitrates is mediated by a cytochrome P-450 enzyme system rather than by glutathione S-transferase or free thiols. Nitrates 104-112 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 130-146 24178079-0 1992 Coaction of light, nitrate and a plastidic factor in controlling nitrite-reductase gene expression in tobacco. Nitrates 19-26 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 65-82 24178079-1 1992 Nitrite reductase (NIR; EC 1.7.7.1) - a key enzyme of nitrate reduction - is known to be induced by nitrate and light. Nitrates 54-61 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 0-17 24178079-1 1992 Nitrite reductase (NIR; EC 1.7.7.1) - a key enzyme of nitrate reduction - is known to be induced by nitrate and light. Nitrates 54-61 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 19-22 24178079-1 1992 Nitrite reductase (NIR; EC 1.7.7.1) - a key enzyme of nitrate reduction - is known to be induced by nitrate and light. Nitrates 100-107 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 0-17 24178079-1 1992 Nitrite reductase (NIR; EC 1.7.7.1) - a key enzyme of nitrate reduction - is known to be induced by nitrate and light. Nitrates 100-107 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 19-22 24178079-2 1992 In the present study with tobacco (Nicotiana tabacum L.) seedlings the dependency of NIR gene expression on nitrate, light and a plastidic factor was investigated to establish the nature of the coaction between these controlling factors. Nitrates 108-115 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 85-88 24178079-9 1992 (iv) Northern blot analysis of NIR-transcript levels indicated that a low transcript level existed in the absence of nitrate and light; however, this level appeared to be increased slightly by light (in the absence of nitrate) and by nitrate (in the absence of light). Nitrates 117-124 ferredoxin--nitrite reductase, chloroplastic-like Nicotiana tabacum 31-34 24178047-6 1992 It appears that in bundle-sheath cells of maize the nitrate-assimilatory capacities of glutamine synthetase (located mainly in the cytosol) and of glutamate synthase (located in the stroma) are high enough to meet the demands of whole maize leaves. Nitrates 52-59 ferredoxin-dependent glutamate synthase, chloroplastic Zea mays 147-165 1606187-4 1992 Bradykinin had a stimulating effect on human and bovine endothelial cells and led to a threefold increase of nitrite/nitrate in endothelial cell column perfusates compared to those of unstimulated cells. Nitrates 117-124 kininogen 1 Homo sapiens 0-10 16668807-0 1992 Effects of Nitrate and Ammonium on Gene Expression of Phosphoenolpyruvate Carboxylase and Nitrogen Metabolism in Maize Leaf Tissue during Recovery from Nitrogen Stress. Nitrates 11-18 MLO-like protein 4 Zea mays 54-85 16668807-1 1992 We previously showed that the selective accumulation of phosphoenolpyruvate carboxylase (PEPC) in photosynthetically maturing maize (Zea mays L.) leaf cells induced by nitrate supply to nitrogen-starved plants was primarily a consequence of the level of its mRNA (B Sugiharto, K Miyata, H Nakamoto, H Sasakawa, T Sugiyama [1990] Plant Physiol 92: 963-969). Nitrates 168-175 MLO-like protein 4 Zea mays 56-87 16668807-1 1992 We previously showed that the selective accumulation of phosphoenolpyruvate carboxylase (PEPC) in photosynthetically maturing maize (Zea mays L.) leaf cells induced by nitrate supply to nitrogen-starved plants was primarily a consequence of the level of its mRNA (B Sugiharto, K Miyata, H Nakamoto, H Sasakawa, T Sugiyama [1990] Plant Physiol 92: 963-969). Nitrates 168-175 MLO-like protein 4 Zea mays 89-93 1558158-3 1992 Substitution of Cl- with nitrate (101 mM) stimulated renin secretion. Nitrates 25-32 renin Rattus norvegicus 53-58 1541678-4 1992 Activity of this pathway was evaluated by measuring serum and urine nitrate (the stable degradation product of NO) during IL-2 therapy. Nitrates 68-75 interleukin 2 Homo sapiens 122-126 1541678-5 1992 IL-2 administration caused a striking increase in NO generation as reflected by serum nitrate levels (10- and 8-fold increase [P less than 0.001, P less than 0.003] for RCC and MM patients, respectively) and 24-h urinary nitrate excretion (6.5- and 9-fold increase [both P less than 0.001] for RCC and MM patients, respectively). Nitrates 86-93 interleukin 2 Homo sapiens 0-4 1541678-5 1992 IL-2 administration caused a striking increase in NO generation as reflected by serum nitrate levels (10- and 8-fold increase [P less than 0.001, P less than 0.003] for RCC and MM patients, respectively) and 24-h urinary nitrate excretion (6.5- and 9-fold increase [both P less than 0.001] for RCC and MM patients, respectively). Nitrates 221-228 interleukin 2 Homo sapiens 0-4 1541678-6 1992 IL-2-induced renal dysfunction made only a minor contribution to increased serum nitrate levels. Nitrates 81-88 interleukin 2 Homo sapiens 0-4 1541678-8 1992 Our results showing increased endogenous nitrate synthesis in patients receiving IL-2 demonstrate for the first time that a cytokine-inducible, high-output L-arginine/NO pathway exists in humans. Nitrates 41-48 interleukin 2 Homo sapiens 81-85 1542684-1 1992 Nitrate reductase, the first enzyme in nitrate assimilation, is located at the crossroad of two energy-consuming pathways: nitrate assimilation and carbon fixation. Nitrates 39-46 nitrate reductase 1 Arabidopsis thaliana 0-17 1542684-1 1992 Nitrate reductase, the first enzyme in nitrate assimilation, is located at the crossroad of two energy-consuming pathways: nitrate assimilation and carbon fixation. Nitrates 123-130 nitrate reductase 1 Arabidopsis thaliana 0-17 16668656-3 1992 In mutants defective at the regulatory locus for nitrate reductase (nit-2), very low levels of nitrite uptake and nitrite reductase activities were expressed even in the presence of nitrate or nitrite. Nitrates 49-56 uncharacterized protein Chlamydomonas reinhardtii 68-73 1557942-4 1992 EDRF-NO as well as NO generated from vasodilator nitrates act by activation of soluble guanylate cyclase, elevating cellular cyclic GMP levels, causing vasodilatation and inhibition of platelet aggregation. Nitrates 49-57 5'-nucleotidase, cytosolic II Homo sapiens 132-135 1462853-6 1992 As a consequence, SH-containing ACE-inhibitors may potentiate nitrates, because they act as exogenous nitrovasodilators, and reverse tolerance to their therapeutic effect. Nitrates 62-70 angiotensin I converting enzyme Homo sapiens 32-35 15092051-4 1992 It is suggested that the most likely mechanism for this nitrate production was due to the solution of N2O5 and NO3 formed from the reaction of NO2 with O3. Nitrates 56-63 NBL1, DAN family BMP antagonist Homo sapiens 111-114 1731978-0 1992 Nitrate reductase transcript is expressed in the primary response of maize to environmental nitrate. Nitrates 92-99 nitrate reductase [NADH] 1 Zea mays 0-17 1731978-1 1992 The nitrate induction of NADH:nitrate reductase mRNA in maize roots, scutella and leaves was investigated in the presence and absence of inhibitors of protein synthesis. Nitrates 4-11 nitrate reductase [NADH] 1 Zea mays 30-47 1731978-2 1992 In the absence of inhibitors, nitrate treatment caused a fairly rapid (2 to 3 h) increase in the level of the nitrate reductase transcript in all tissues. Nitrates 30-37 nitrate reductase [NADH] 1 Zea mays 110-127 1731978-3 1992 When cytoplasmic protein synthesis was inhibited by cycloheximide, nitrate reductase mRNA was induced by nitrate in all tissues to levels equal to or greater than those found with nitrate treatment alone. Nitrates 105-112 nitrate reductase [NADH] 1 Zea mays 67-84 1864311-0 1991 Nitrate-induced hypothyroidism is associated with a reduced concentration of growth hormone-releasing factor in hypothalamic tissue of rats. Nitrates 0-7 growth hormone releasing hormone Rattus norvegicus 77-108 16668164-3 1991 Although nitrate-induction kinetics of the two genes are very similar, NR1 is expressed in the absence of nitrate at a higher basal level than NR2. Nitrates 9-16 nitrate reductase 1 Arabidopsis thaliana 71-74 16668164-3 1991 Although nitrate-induction kinetics of the two genes are very similar, NR1 is expressed in the absence of nitrate at a higher basal level than NR2. Nitrates 9-16 nitrate reductase 2 Arabidopsis thaliana 143-146 16668164-3 1991 Although nitrate-induction kinetics of the two genes are very similar, NR1 is expressed in the absence of nitrate at a higher basal level than NR2. Nitrates 106-113 nitrate reductase 1 Arabidopsis thaliana 71-74 1790782-4 1991 At least one further site in the nitrate bioconversion cascade, possibly at the level of NO generation appears to be involved in tolerance development, which may also affect the non-nitrate vasodilator SIN-1. Nitrates 33-40 MAPK associated protein 1 Homo sapiens 202-207 16668525-9 1991 Chlorate-treated plants still retain the capacity to make functional NR because NR activity could be restored by irrigating the chlorate-treated plants with nitrate. Nitrates 157-164 nitrate reductase 1 Arabidopsis thaliana 80-82 1720843-3 1991 In nitrate-tolerant hearts of rats pretreated with isosorbide dinitrate (15 mg daily), the increase in coronary flow by nitroglycerin and bradykinin was significantly less when compared to control hearts. Nitrates 3-10 kininogen 1 Homo sapiens 138-148 1911837-0 1991 The binding of nitrate to the human anion exchange protein (AE1) studied with 14N nuclear magnetic resonance. Nitrates 15-22 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 60-63 1911837-3 1991 Addition of the AE1 specific inhibitor 4,4"-dinitrostilbene-2,2"-disulfonate markedly reduced this line-broadening, indicating that the broadening was predominantly due to a specific interaction between nitrate and AE1. Nitrates 203-210 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 16-19 1911837-4 1991 The dependence of the AE1 specific line-broadening on nitrate concentration had a first-order dissociation constant KD of 6.9 +/- 0.9 mM. Nitrates 54-61 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 22-25 1911837-5 1991 In contrast, Cl- interaction with AE1 studied by 35Cl-NMR showed a chloride concentration-dependent line-broadening with a KD of 74 +/- 10 mM, indicating that AE1 has a higher affinity for nitrate than for chloride. Nitrates 189-196 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 34-37 1911837-5 1991 In contrast, Cl- interaction with AE1 studied by 35Cl-NMR showed a chloride concentration-dependent line-broadening with a KD of 74 +/- 10 mM, indicating that AE1 has a higher affinity for nitrate than for chloride. Nitrates 189-196 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 159-162 1911837-8 1991 Nitrate is a structural analog of bicarbonate, making the interaction of nitrate with AE1 a good model for the bicarbonate-AE1 interaction. Nitrates 0-7 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 86-89 1911837-8 1991 Nitrate is a structural analog of bicarbonate, making the interaction of nitrate with AE1 a good model for the bicarbonate-AE1 interaction. Nitrates 0-7 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 123-126 1911837-8 1991 Nitrate is a structural analog of bicarbonate, making the interaction of nitrate with AE1 a good model for the bicarbonate-AE1 interaction. Nitrates 73-80 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 86-89 1911837-8 1991 Nitrate is a structural analog of bicarbonate, making the interaction of nitrate with AE1 a good model for the bicarbonate-AE1 interaction. Nitrates 73-80 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 123-126 1911837-9 1991 The 14N-NMR nitrate binding assay, along with the 35Cl-NMR binding assay now in use, will provide a powerful tool for studying the structure of the AE1 binding site for both physiologic substrates, bicarbonate and chloride. Nitrates 12-19 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 148-151 1712676-11 1991 The activity for forming L-citrulline and nitrite/nitrate from L-arginine was markedly induced by treatment with either LPS alone or LPS + IFN-gamma but not with IFN-gamma. Nitrates 50-57 interferon gamma Mus musculus 139-148 1831867-1 1991 Effects of nicorandil (2-nicotinamidoethyl nitrate), a nitrate derivative with a K+ channel-opening action, on endothelin-1 (ET)-induced effects on peripheral blood vessels were studied using a hind-limb perfusion preparation in rats. Nitrates 43-50 endothelin 1 Rattus norvegicus 111-123 1903680-0 1991 Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta. Nitrates 12-20 coagulation factor II, thrombin Homo sapiens 33-41 1903680-6 1991 However, the nitrates fully inhibited the release of the peptide induced by thrombin (4 units/ml). Nitrates 13-21 coagulation factor II, thrombin Homo sapiens 76-84 1874272-3 1991 EDRF-NO and NO generated from vasodilator nitrates work by activation of soluble guanylate cyclase, elevating cyclic guanosine monophosphate (GMP) levels to cause vasodilatation and inhibition of platelet aggregation. Nitrates 42-50 alpha hemoglobin stabilizing protein Homo sapiens 0-4 1901528-12 1991 Body weight increased only in the placebo group, suggesting prevention of nitrate-induced volume expansion in the ACE inhibitor groups. Nitrates 74-81 angiotensin I converting enzyme Homo sapiens 114-117 1901528-13 1991 CONCLUSIONS: This study demonstrates that ACE inhibitors may prevent nitrate tolerance to long-term nitrate therapy. Nitrates 69-76 angiotensin I converting enzyme Homo sapiens 42-45 1901528-13 1991 CONCLUSIONS: This study demonstrates that ACE inhibitors may prevent nitrate tolerance to long-term nitrate therapy. Nitrates 100-107 angiotensin I converting enzyme Homo sapiens 42-45 1906734-0 1991 Effect of nitrate tolerance and dipyridamole on the response to SIN1 in the human isolated saphenous vein. Nitrates 10-17 MAPK associated protein 1 Homo sapiens 64-68 1864311-7 1991 Nitrate exposure is characterized by hypothyroidism, food intake depression, low Sm-C/IGF-I concentrations in plasma and a decreased hypothalamic GRF content. Nitrates 0-7 insulin-like growth factor 1 Rattus norvegicus 86-91 1846742-2 1991 Reduction of nitrate, or nitrite, to N2O under aerobic conditions involves NO as an intermediate, as judged by trapping experiments with the ferric form of extracellular horse heart cytochrome c and the demonstration that the cells possess a nitric oxide reductase activity. Nitrates 13-20 cytochrome c, somatic Equus caballus 182-194 1906734-6 1991 Dipyridamole, a phosphodiesterase (PDe) inhibitor, significantly potentiated the responses to SIN1 on control rings (EC50 = 57.1 +/- 1.8 nM), and on NTG-tolerant rings it reversed the responsiveness to SIN1 (EC50 = 88.9 +/- 9.2 nM), which suggests that nitrate tolerance may be partially due to an increase in PDe activity. Nitrates 253-260 MAPK associated protein 1 Homo sapiens 94-98 1988109-2 1991 We show here that FAA and structurally related analogues increase plasma nitrite plus nitrate (NO2-/NO3-) levels in mice. Nitrates 86-93 NBL1, DAN family BMP antagonist Mus musculus 95-103 1989691-4 1991 Nitrate reductase specific mRNA can be observed within 2 h after nitrate treatment. Nitrates 65-72 inducible nitrate reductase [NADH] 1 Glycine max 0-17 1989691-5 1991 Levels peaked 48 h after nitrate treatment, while the addition of glutamine to nitrate diminished amounts of nitrate reductase specific mRNA. Nitrates 79-86 inducible nitrate reductase [NADH] 1 Glycine max 109-126 1859433-0 1991 Regulation of phosphoenolpyruvate carboxylase from maize leaves by nitrate and alanine. Nitrates 67-74 MLO-like protein 4 Zea mays 14-45 1859433-1 1991 Nitrate and alanine were found to stimulate partially purified maize leaf phosphoenolpyruvate carboxylase under specific assay conditions. Nitrates 0-7 MLO-like protein 4 Zea mays 74-105 1649801-5 1991 In a cohort of 1,148 male fertilizer workers who had never been exposed to nitrate, there was an increased incidence of lung cancer (SMR = 151,95% CI = 103-220) but not of stomach cancer or prostate cancer. Nitrates 75-82 LY6/PLAUR domain containing 4 Homo sapiens 133-136 1776339-1 1991 SIN 1, the bioactive metabolite of molsidomine, not only appears to lack the problem of inducing nitrate tolerance, but also exerts antiaggregatory and fibrinolytic properties. Nitrates 97-104 MAPK associated protein 1 Homo sapiens 0-5 16667965-1 1991 The level of nitrate reductase (NR) and nitrite reductase (NiR) varied in both shoot and root tissue from nitrate-fed Zea mays L. grown under a 16-hour light/8-hour dark regime over a 10-day period postgermination, with peak activity occurring in days 5 to 6. Nitrates 13-20 nitrate reductase [NADH] 1 Zea mays 32-34 2128204-7 1990 This suggests that the biotransformation of organic nitrates can occur through the direct interaction with the heme moiety of cytochrome P-450. Nitrates 52-60 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 126-142 2128204-10 1990 These data suggest that cytochrome P-450 is involved in the biotransformation of organic nitrates and raises the possibility that vascular cytochrome P-450 may play a role in the mechanism-based biotransformation of organic nitrates, the result of which is vascular smooth muscle relaxation. Nitrates 89-97 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 24-40 2128204-10 1990 These data suggest that cytochrome P-450 is involved in the biotransformation of organic nitrates and raises the possibility that vascular cytochrome P-450 may play a role in the mechanism-based biotransformation of organic nitrates, the result of which is vascular smooth muscle relaxation. Nitrates 89-97 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 139-155 2128204-10 1990 These data suggest that cytochrome P-450 is involved in the biotransformation of organic nitrates and raises the possibility that vascular cytochrome P-450 may play a role in the mechanism-based biotransformation of organic nitrates, the result of which is vascular smooth muscle relaxation. Nitrates 224-232 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 24-40 2128204-10 1990 These data suggest that cytochrome P-450 is involved in the biotransformation of organic nitrates and raises the possibility that vascular cytochrome P-450 may play a role in the mechanism-based biotransformation of organic nitrates, the result of which is vascular smooth muscle relaxation. Nitrates 224-232 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 139-155 16667714-3 1990 CA activity was reduced in plants grown under nitrogen deficiency and recovered only slowly when supplemented with nitrate. Nitrates 115-122 carbonic anhydrase Zea mays 0-2 2124251-1 1990 The present study demonstrates that murine dermal fibroblasts produce nitrite (NO2-) and nitrate (NO3-) upon treatment with interferon gamma (IFN-gamma). Nitrates 89-96 NBL1, DAN family BMP antagonist Mus musculus 98-101 2124251-1 1990 The present study demonstrates that murine dermal fibroblasts produce nitrite (NO2-) and nitrate (NO3-) upon treatment with interferon gamma (IFN-gamma). Nitrates 89-96 interferon gamma Mus musculus 124-151 1965331-7 1990 These results suggest that in intact cells, glyceryl trinitrate-induced cyclic GMP stimulation is dependent on cytochrome P-450 enzymes which may be relevant for nitric oxide formation from organic nitrates. Nitrates 198-206 cytochrome P450 family 2 subfamily D member 6 Sus scrofa 111-127 24197373-2 1990 This is demonstrated by the properties of the associated ATPase: high vanadate sensitivity, azide and nitrate insensitivity, sharp pH optimum around 6.5, and high specificity for ATP as substrate. Nitrates 102-109 dynein axonemal heavy chain 8 Homo sapiens 57-63 24197091-5 1990 Seedlings germinated from seeds (pericarp was removed) without external N-supply are able to take up nitrate immediately upon exposure via a low-capacity uptake system (vmax = 0.8 mumol NO 3 (-) (g root FW)(-1) h(-1); Ks = 0.12 mM). Nitrates 101-108 NBL1, DAN family BMP antagonist Homo sapiens 186-190 24197091-7 1990 Induction of a high-capacity nitrate-uptake system (vmax = 3.4 mumol NO 3 (-) (g root FW)(-1) h(-1); Ks = 0.08 mM) by externally supplied nitrate occurs after a 20-min lag and requires protein synthesis. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 69-73 24197091-7 1990 Induction of a high-capacity nitrate-uptake system (vmax = 3.4 mumol NO 3 (-) (g root FW)(-1) h(-1); Ks = 0.08 mM) by externally supplied nitrate occurs after a 20-min lag and requires protein synthesis. Nitrates 139-146 NBL1, DAN family BMP antagonist Homo sapiens 69-73 2111676-3 1990 The mechanism of tolerance to nitrates is multifactorial, related on the one hand to depletion of sulfhydryl groups in the body and on the other to activation of the sympathetic and renin-angiotensin systems. Nitrates 30-38 renin Homo sapiens 182-187 2102014-4 1990 Since the eight day of perfusion all the effluents had an important concentration of nitrate (Figure 1), exceeding in them, the sum of [No-2-N] an [NO-3-N] (Table 1) the concentration of th NO-2-N of the perfusion solution. Nitrates 85-92 NBL1, DAN family BMP antagonist Homo sapiens 148-152 2382514-3 1990 Nitrate (in the assayed range 0 to 800 mg/L) and high concentrations of ascorbic acid (4 to 8 g/L) slightly inhibited cathepsin D. Nitrates 0-7 cathepsin D Homo sapiens 118-129 2115855-9 1990 The cause of nitrate tolerance is regarded as an insufficient or absent stimulation of guanylate cyclase and, consequently, inadequate generation of cyclic GMP due to availability of thiol substrate. Nitrates 13-20 5'-nucleotidase, cytosolic II Homo sapiens 156-159 1972336-10 1990 At this temperature, even weak chaotropic anions (fluoride, chloride and nitrate), while in combination with non-ionic detergents that solubilized mosquito AChE efficiently, reduced the enzyme activity of these fractions. Nitrates 73-80 acetylcholinesterase (Cartwright blood group) Homo sapiens 156-160 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 75-82 NOD3 Glycine max 20-26 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 75-82 NOD3 Glycine max 28-34 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 75-82 NOD3 Glycine max 40-46 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 88-95 NOD3 Glycine max 20-26 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 88-95 NOD3 Glycine max 28-34 16667382-2 1990 nodulation mutants (NOD1-3, NOD2-4, and NOD3-7) were partially tolerant to nitrate when nitrate was supplied simultaneously with inoculation at the time of transplanting. Nitrates 88-95 NOD3 Glycine max 40-46 16667382-6 1990 NOD1-3 was most tolerant of nitrate among the mutants tested and showed the highest relative abundance of ureides. Nitrates 28-35 NOD3 Glycine max 0-6 16667382-10 1990 Unexpectedly, nitrate treatment also increased the rate of ureide degradative capacity of leaves in both NOD1-3 and Williams. Nitrates 14-21 NOD3 Glycine max 105-111 2113002-10 1990 Thus, the administration of low doses of nitrates that act by means of the NO radical can increase the diameter in the stenosis, since the physiological dilator (EDRF) is no longer present. Nitrates 41-49 alpha hemoglobin stabilizing protein Homo sapiens 162-166 2354740-6 1990 Average nitrate intake was 52 mg NO3-/day, about 25% of the ADI. Nitrates 8-15 NBL1, DAN family BMP antagonist Homo sapiens 33-36 2099413-0 1990 Inhibition of platelet activation by the nitrate Sin-1: studies with human aequorin-loaded platelets. Nitrates 41-48 MAPK associated protein 1 Homo sapiens 49-54 33971470-1 2021 Fluoride (F-) and nitrate (NO3-) in groundwater have caused serious health problems worldwide. Nitrates 18-25 NBL1, DAN family BMP antagonist Homo sapiens 27-30 25762424-5 2015 The best retrieval of modeled nitrate (R2=0.527, root mean square error (RMSE)=3.72, and mean normalized bias (MNB)=0.821) was observed for the postmonsoon season due to the better retrieval of both SST MODIS (28 February 2012, R2=0.651, RMSE=2.037, and MNB=0.068) and chl OCM-2 (R2=0.534, RMSE=0.317, and MNB=0.27). Nitrates 30-37 oncomodulin 2 Homo sapiens 273-278 33968104-1 2021 As important electron carriers, ferredoxin (Fd) proteins play important roles in photosynthesis, and the assimilation of CO2, nitrate, sulfate, and other metabolites. Nitrates 126-133 ferredoxin Zea mays 32-42 33822357-21 2021 Based on low-certainty evidence, beta-blockers plus nitrates had a higher number of "any adverse events (number of participants)" than beta-blockers alone (OR 3.41, 95% CrI 1.11 to 11.28; 1 trial, 57 participants). Nitrates 52-60 EP300 interacting inhibitor of differentiation 1 Homo sapiens 169-174 33822357-24 2021 Based on low-certainty evidence, any variceal bleed was higher in nitrates than beta-blockers (direct comparison HR 6.40, 95% CrI 1.58 to 47.42; 1 trial, 52 participants). Nitrates 66-74 EP300 interacting inhibitor of differentiation 1 Homo sapiens 126-131 33804377-4 2021 The nitrate concentrations in the drinking water ranged from 3.55 mg/L to 26.75 mg/L as NO3-. Nitrates 4-11 NBL1, DAN family BMP antagonist Homo sapiens 88-91 33031018-1 2020 Ingestion of dietary nitrate (NO3-) is associated with improved exercise tolerance and reduced oxygen (O2) cost of exercise, ascribed to enhanced mitochondrial efficiency, muscle contractile function or other factors. Nitrates 21-28 NBL1, DAN family BMP antagonist Homo sapiens 30-33 32794734-5 2020 Adding nitrate to a solution of the [Cm(nPr-BTP)3]3+ complex in 2-propanol shifts the Cm(III) emission band from 613.1 to 617.3 nm. Nitrates 7-14 neuronal pentraxin receptor Homo sapiens 40-43 32794734-12 2020 The vibronic side band of the [Cm(nPr-BTP)3(NO3)]2+ complex exhibits a nitrate stretching mode not observed in the [Cm(nPr-BTP)3]3+ complex. Nitrates 71-78 neuronal pentraxin receptor Homo sapiens 34-37 32794734-12 2020 The vibronic side band of the [Cm(nPr-BTP)3(NO3)]2+ complex exhibits a nitrate stretching mode not observed in the [Cm(nPr-BTP)3]3+ complex. Nitrates 71-78 NBL1, DAN family BMP antagonist Homo sapiens 44-47 32794734-12 2020 The vibronic side band of the [Cm(nPr-BTP)3(NO3)]2+ complex exhibits a nitrate stretching mode not observed in the [Cm(nPr-BTP)3]3+ complex. Nitrates 71-78 neuronal pentraxin receptor Homo sapiens 119-122 32794734-13 2020 Moreover, XPS on [M(nPr-BTP)3(NO3)](NO3)2 (M = Eu, Am) yields signals from both non-coordinated and coordinated nitrate. Nitrates 112-119 neuronal pentraxin receptor Homo sapiens 20-23 32794734-13 2020 Moreover, XPS on [M(nPr-BTP)3(NO3)](NO3)2 (M = Eu, Am) yields signals from both non-coordinated and coordinated nitrate. Nitrates 112-119 NBL1, DAN family BMP antagonist Homo sapiens 30-33 32794734-13 2020 Moreover, XPS on [M(nPr-BTP)3(NO3)](NO3)2 (M = Eu, Am) yields signals from both non-coordinated and coordinated nitrate. Nitrates 112-119 NBL1, DAN family BMP antagonist Homo sapiens 36-39 32794734-14 2020 Finally, DFT calculations reveal that the energetically most favored structure is obtained if the nitrate is positioned on the C2 axis of the D3 symmetrical [Cm(nPr-BTP)3]3+ complex with a bond distance of 413 pm. Nitrates 98-105 neuronal pentraxin receptor Homo sapiens 161-164 31139154-9 2019 The maximum rates of different redox metabolisms (mM electron acceptors reduced g-1 soil d-1) in soil containing biogenic nitrate followed as: NO3 1- reduction 4.01 +- 0.22, Fe3+ reduction 5.37 +- 0.12, SO4 2- reduction 9.56 +- 0.16, and CH4 production (mug g-1 soil) 0.46 +- 0.05. Nitrates 122-129 NBL1, DAN family BMP antagonist Homo sapiens 143-146 31139154-11 2019 Raman spectra indicated that aliphatic hydrocarbons increased in soil during nitrification, and these compounds probably bind to NO3 to form biogenic nitrate. Nitrates 150-157 NBL1, DAN family BMP antagonist Homo sapiens 129-132 29378007-9 2018 Nitrate-independent phenotypes were found with higher seed abortion in atg5 and early browing, higher total protein concentrations in the viable seeds of this mutant as compared to the WT. Nitrates 0-7 SAC domain-containing protein 8 Arabidopsis thaliana 71-75 25762424-6 2015 Present results confirm that the chl OCM-2 and SST MODIS retrieve nitrate well than the MODIS-derived chl and SST largely due to the better retrieval of chl by OCM-2 than MODIS. Nitrates 66-73 oncomodulin 2 Homo sapiens 37-42 25805369-7 2015 The spatial distribution of NO3--N export from hydrologic response units (HRUs) identified the agricultural areas with surplus N that are vulnerable to nitrate contamination. Nitrates 152-159 NBL1, DAN family BMP antagonist Homo sapiens 28-31 23214130-4 2012 Two families of proton-coupled symporters, NRT1 and NRT2, and one type of proton-coupled antiporters, CIC, have been shown to be involved in nitrate transport in higher plants. Nitrates 141-148 nitrate transporter 1.1 Arabidopsis thaliana 43-47 23214130-5 2012 The recent progress in research on NRT1 proteins has shed the light on the localization and physiological function of those nitrate transporters in the NO3(-) uptake, NO3(-) cell-to-cell and tissue-to-tissue distribution, nitrates accumulation and efflux within the model plant Arabidopsis thaliana. Nitrates 222-230 nitrate transporter 1.1 Arabidopsis thaliana 35-39 7579165-3 1995 In this paper, we present detailed evidence to show that PMA mimics the red light effect and follows similar kinetics to enhance NR steady-state transcript accumulation in a nitrate-dependent manner. Nitrates 174-181 nitrate reductase [NADH] 1 Zea mays 129-131 34863569-5 2022 The AO7 removal performance of PC-MnOx was slightly decreased in natural waterbodies and in the presence of CO32-, while it showed an anti-interference capacity for Cl-, NO3- and humic acid. Nitrates 170-174 ring finger protein 25 Homo sapiens 4-7 34953459-3 2022 The voltammetry showed that the redox couple of Co(II)/Co(III) and Ni(II)/Ni(III) as the mediator catalytically transferred the electrons of NO2-/NO3-; the Ni site had a relatively high transfer coefficient and diffusive current, while the Co site was better in the capacitive removal of the nitrite and nitrate compounds. Nitrates 146-150 mitochondrially encoded cytochrome c oxidase II Homo sapiens 48-54 34953459-3 2022 The voltammetry showed that the redox couple of Co(II)/Co(III) and Ni(II)/Ni(III) as the mediator catalytically transferred the electrons of NO2-/NO3-; the Ni site had a relatively high transfer coefficient and diffusive current, while the Co site was better in the capacitive removal of the nitrite and nitrate compounds. Nitrates 304-311 mitochondrially encoded cytochrome c oxidase II Homo sapiens 48-54 34743794-1 2022 The green and efficient removal of nitrate (NO3-) in groundwater is a primary concern nowadays, and membrane capacitive deionization (MCDI) is an emerging technology for the removal of nitrate (NO3-) from water. Nitrates 35-42 NBL1, DAN family BMP antagonist Homo sapiens 44-47 34743794-1 2022 The green and efficient removal of nitrate (NO3-) in groundwater is a primary concern nowadays, and membrane capacitive deionization (MCDI) is an emerging technology for the removal of nitrate (NO3-) from water. Nitrates 185-192 NBL1, DAN family BMP antagonist Homo sapiens 44-47 34743794-1 2022 The green and efficient removal of nitrate (NO3-) in groundwater is a primary concern nowadays, and membrane capacitive deionization (MCDI) is an emerging technology for the removal of nitrate (NO3-) from water. Nitrates 185-192 NBL1, DAN family BMP antagonist Homo sapiens 194-197 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Nitrates 367-374 NBL1, DAN family BMP antagonist Homo sapiens 28-31 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Nitrates 367-374 NBL1, DAN family BMP antagonist Homo sapiens 120-123 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Nitrates 367-374 NBL1, DAN family BMP antagonist Homo sapiens 316-319 34896495-4 2022 Nowadays, there is increasing concern about the presence of nitrates (NO3-) in groundwaters as a consequence of the intensive use of fertilizers and other anthropogenic sources, such as sewage or industrial wastewater discharge. Nitrates 60-68 NBL1, DAN family BMP antagonist Homo sapiens 70-73 34896495-6 2022 Thus, this work collects data from the literature regarding the presence of nitrates in groundwater, and, simultaneously, it reviews the main alternatives available to remove NO3- from groundwater sources. Nitrates 76-84 NBL1, DAN family BMP antagonist Homo sapiens 175-178 34806833-0 2022 Electrified conversion of contaminated water to value: selective conversion of aqueous nitrate to ammonia in a PEM cell. Nitrates 87-94 mucin 1, cell surface associated Homo sapiens 111-114 34806833-1 2022 The application of a polymer electrolyte membrane (PEM) electrolytic cell for continuous conversion of nitrate, one of the contaminants in water, to ammonia at the cathode was explored in the present work. Nitrates 103-110 mucin 1, cell surface associated Homo sapiens 51-54 34500153-4 2022 Then, the dissociation of CMC-DD2 was efficiently triggered by intracellular hydrogen peroxide (H2O2) with the release of DNA damaging agents, including nitrate anions, hydroxyl radicals ( OH) and DD2. Nitrates 153-160 aldo-keto reductase family 1 member C2 Homo sapiens 30-33 34914357-1 2022 Electrocatalytic nitrate (NO3-) reduction to N2 via atomic hydrogen (H*) is a promising approach for advanced water treatment. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 26-29 34509834-5 2022 The nitrate mass fraction increased during the three haze episodes, with nitrate accounting for 27-33% of PM1 mass. Nitrates 73-80 transmembrane protein 11 Homo sapiens 106-109 34343879-1 2022 Electroreduction of nitrate (NO3-) to value-added ammonia (NH3) provides an alternative to NH3 production industry and remediation of NO3--containing wastewater. Nitrates 20-27 NBL1, DAN family BMP antagonist Homo sapiens 29-32 34343879-1 2022 Electroreduction of nitrate (NO3-) to value-added ammonia (NH3) provides an alternative to NH3 production industry and remediation of NO3--containing wastewater. Nitrates 20-27 NBL1, DAN family BMP antagonist Homo sapiens 134-137 34426281-2 2022 The scope of this work is the development of a mechanistic biokinetic model, based on first principles and a robust thermodynamic basis, to provide a theoretical accurate description of a MET system that would treat water contaminated with nitrate, the most common aquifer water pollutant, in absence of external electron donors. Nitrates 240-247 SAFB like transcription modulator Homo sapiens 188-191 34923327-1 2022 The present research reports the level of nitrate (NO3-), associated health risks and possible sources of contamination in groundwater from south India. Nitrates 42-49 NBL1, DAN family BMP antagonist Homo sapiens 51-54 34940921-10 2022 There was an increase in nitrate levels of CSF and CSF/plasma ratio of nitrate in patients with PD and LID compared to the healthy controls. Nitrates 25-32 colony stimulating factor 2 Homo sapiens 43-46 34940921-10 2022 There was an increase in nitrate levels of CSF and CSF/plasma ratio of nitrate in patients with PD and LID compared to the healthy controls. Nitrates 71-78 colony stimulating factor 2 Homo sapiens 51-54 34814021-8 2022 In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively. Nitrates 52-59 CD59 molecule (CD59 blood group) Homo sapiens 179-189 34814021-8 2022 In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively. Nitrates 118-125 CD59 molecule (CD59 blood group) Homo sapiens 179-189 34968494-11 2022 Inorganic nitrites and nitrates can decrease the risk for osteoporotic fracture probably directly by decreasing osteoclast activity, decreasing fat accumulation in the marrow cavity, increasing osteoblast activity, and increasing bone perfusion or indirectly, by improving hyperglycemia, insulin resistance, and reducing body weight. Nitrates 23-31 insulin Homo sapiens 288-295 34967938-7 2021 RESULTS: Administration of Klotho protein resulted in mitigation of injury, decreased level of NOX2 and NOX4, reduced generation of ROS/RNS and hydrogen peroxide (H2O2), decreased expression of inducible NOS and limited production of nitrates/nitrites in cells under I/R. Nitrates 234-242 klotho Homo sapiens 27-33 34974023-3 2022 Ice cores contain records of nitrogen species of nitrate (NO3-) and ammonium (NH4+), hence provide valuable long-term data to study past variations of atmospheric nitrogen deposition. Nitrates 49-56 NBL1, DAN family BMP antagonist Homo sapiens 58-61 34486076-7 2021 We selected seven homologs containing conserved features of AtRIN4, including two NOI (Nitrate induced) domains, each containing a predicted cleavage site for AvrRpt2, and a C-terminal palmitoylation site predicted to mediate membrane tethering of the proteins. Nitrates 87-94 RPM1 interacting protein 4 Arabidopsis thaliana 60-66 34467905-7 2021 In comparison with a control, the Kyoto Encyclopedia of Genes and Genomes analysis showed that wastewater salinity weakened the functional gene level of MBR microbial flora, and the enzyme key to the assimilation nitrate reduction changed from nitrate reductase to assimilation nitrate reductase. Nitrates 213-220 translocator protein Homo sapiens 153-156 34467905-7 2021 In comparison with a control, the Kyoto Encyclopedia of Genes and Genomes analysis showed that wastewater salinity weakened the functional gene level of MBR microbial flora, and the enzyme key to the assimilation nitrate reduction changed from nitrate reductase to assimilation nitrate reductase. Nitrates 278-285 translocator protein Homo sapiens 153-156 34912897-9 2021 Methanolic extract of S. kurramense decreased CCl4-induced hepatotoxicity by increasing the antioxidant status and reducing H2O2 and nitrate content generation as well as reducing DNA damage. Nitrates 133-140 C-C motif chemokine ligand 4 Rattus norvegicus 46-50 34927377-1 2022 Nitrate (NO 3 - ) as a common pollutant under groundwater causes drinking water safety problems and seriously endangers people"s health. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-13 34927377-2 2022 Electrochemistry reduction nitrate to ammonia under ambient condition is a green and significant route to reduce the concentration of NO 3 - and produce ammonia (NH 3 ), known as a complement to the Haber-Bosch reaction. Nitrates 27-34 NBL1, DAN family BMP antagonist Homo sapiens 134-138 34919376-6 2021 Owing to the strong adsorption of nitrate on Fe0 active sites generated via topotactic conversion and in situ electroreduction, 2D Fe-cyano electrocatalyst exhibits high catalytic activity with a yield rate of 42.1 mg h-1 mgcat-1 and a Faradaic efficiency of over 90% toward NH3 production at -0.5 V (vs reversible hydrogen electrode, RHE). Nitrates 34-41 factor interacting with PAPOLA and CPSF1 Homo sapiens 335-338 34870671-1 2021 Nitrogen speciation, i.e. distinguishing nitrate (NO3-) and ammonium (NH4+), is commonly undertaken in soil studies, but has not been conducted extensively for lichens. Nitrates 41-48 NBL1, DAN family BMP antagonist Homo sapiens 50-53 34536740-1 2021 Nitrate (NO3-) leaching has negative human and environmental health consequences that can be attributed to and mitigated by agricultural decision making. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34618055-1 2021 Nitrate (NO3) assimilation and signaling regulate plant growth through the relevant function of the transcription factor NIN-like Protein7 (NLP7). Nitrates 0-7 NIN like protein 7 Arabidopsis thaliana 121-138 34618055-1 2021 Nitrate (NO3) assimilation and signaling regulate plant growth through the relevant function of the transcription factor NIN-like Protein7 (NLP7). Nitrates 0-7 NIN like protein 7 Arabidopsis thaliana 140-144 34524462-0 2021 STOP1 activates NRT1.1-mediated nitrate uptake to create a favorable rhizospheric pH for plant adaptation to acidity. Nitrates 32-39 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 0-5 34524462-0 2021 STOP1 activates NRT1.1-mediated nitrate uptake to create a favorable rhizospheric pH for plant adaptation to acidity. Nitrates 32-39 nitrate transporter 1.1 Arabidopsis thaliana 16-22 34524462-3 2021 Here, we showed that in the roots of Arabidopsis thaliana, the C2H2-type transcription factor STOP1 in the nucleus was enriched by low pH in a nitrate-independent manner, with the spatial expression pattern of NITRATE TRANSPORTER 1.1 (NRT1.1) established by low pH required the action of STOP1. Nitrates 143-150 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 94-99 34524462-5 2021 Molecular assays revealed that STOP1 directly bound to the promoter of NRT1.1 to activate its transcription in response to low pH, thus upregulating its nitrate uptake. Nitrates 153-160 C2H2 and C2HC zinc fingers superfamily protein Arabidopsis thaliana 31-36 34524462-5 2021 Molecular assays revealed that STOP1 directly bound to the promoter of NRT1.1 to activate its transcription in response to low pH, thus upregulating its nitrate uptake. Nitrates 153-160 nitrate transporter 1.1 Arabidopsis thaliana 71-77 34926901-1 2021 Nitrate (NO3 -) contamination is becoming a major concern due to the negative effects of an excessive NO3 - presence in water which can have detrimental effects on human health. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34926901-1 2021 Nitrate (NO3 -) contamination is becoming a major concern due to the negative effects of an excessive NO3 - presence in water which can have detrimental effects on human health. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 102-105 34225116-7 2021 STL addition enhanced nitrification at high temperatures during composting, thus increasing the nitrate content of compost by 2-10 times compared with that of the control group (using tap water as a moisture conditioning agent). Nitrates 96-103 RNF217 antisense RNA 1 (head to head) Homo sapiens 0-3 33342321-6 2021 mC2 sponges exhibited superior in-vitro drug release profiles where ~100% of tenoxicam released within 5 min for fast pain relief with a more prolonged miconazole nitrate release. Nitrates 163-170 complement component 2 (within H-2S) Mus musculus 0-3 34273081-1 2021 Nitrate (NO3-) contamination has become a dominant international problem in the aquatic environment, so identifying the sources and transformations of NO3- is the basis for improving water quality. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34273081-1 2021 Nitrate (NO3-) contamination has become a dominant international problem in the aquatic environment, so identifying the sources and transformations of NO3- is the basis for improving water quality. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 151-154 34467886-1 2021 The annual mean PM2.5 mass concentration has decreased because of the stringent emission controls implemented in Beijing, China in recent years, whereas the nitrate NO3- mass fraction in PM2.5 increases gradually. Nitrates 157-164 NBL1, DAN family BMP antagonist Homo sapiens 165-168 34758438-4 2021 The correlations between the nitrate (NO3-) concentrations and isotopic compositions (delta15N/delta18O-NO3-) indicated the pelagic NO3- loads were largely regulated by mixing between precipitation and sewage. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 38-41 34758438-4 2021 The correlations between the nitrate (NO3-) concentrations and isotopic compositions (delta15N/delta18O-NO3-) indicated the pelagic NO3- loads were largely regulated by mixing between precipitation and sewage. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 104-107 34758438-4 2021 The correlations between the nitrate (NO3-) concentrations and isotopic compositions (delta15N/delta18O-NO3-) indicated the pelagic NO3- loads were largely regulated by mixing between precipitation and sewage. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 132-135 34842136-6 2021 Compared to wild-type mice, isolated perfused kidneys of C451A-ERalpha mice revealed a decreased flow-mediated nitrate production and an increased H2O2 production. Nitrates 111-118 estrogen receptor 1 (alpha) Mus musculus 63-70 34388487-9 2021 Our results suggested that the leaf litter treatment was preferential for nitrate reduction over the mud deposit treatment, with a higher NO3- reduction rate and less NH4+ accumulation during the complete BS process. Nitrates 74-81 NBL1, DAN family BMP antagonist Homo sapiens 138-141 34506950-1 2021 Oral microbiota dysbiosis, concomitant with decreased abundance of nitrate (NO3-)-reducing bacteria, oral net nitrite (NO2-) production, and reduced nitric oxide ( NO) bioactivity, is associated with the development of cardiometabolic disorders. Nitrates 67-74 NBL1, DAN family BMP antagonist Homo sapiens 76-79 34656860-0 2021 The Arabidopsis protein NPF6.2/NRT1.4 is a plasma membrane nitrate transporter and a target of protein kinase CIPK23. Nitrates 59-66 Major facilitator superfamily protein Arabidopsis thaliana 24-30 34656860-0 2021 The Arabidopsis protein NPF6.2/NRT1.4 is a plasma membrane nitrate transporter and a target of protein kinase CIPK23. Nitrates 59-66 CBL-interacting protein kinase 23 Arabidopsis thaliana 110-116 34656860-4 2021 Here we show that NPF6.2/NRT1.4, a protein that gates nitrate accumulation at the leaf petiole of Arabidopsis thaliana, also affects the root/shoot distribution of potassium. Nitrates 54-61 Major facilitator superfamily protein Arabidopsis thaliana 18-24 34656860-5 2021 We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition. Nitrates 55-62 Major facilitator superfamily protein Arabidopsis thaliana 20-26 34656860-5 2021 We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition. Nitrates 55-62 CBL-interacting protein kinase 23 Arabidopsis thaliana 113-119 34542810-0 2021 Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway. Nitrates 0-7 DNA damage inducible transcript 4 Homo sapiens 81-86 34542810-0 2021 Nitrate increases cisplatin chemosensitivity of oral squamous cell carcinoma via REDD1/AKT signaling pathway. Nitrates 0-7 AKT serine/threonine kinase 1 Homo sapiens 87-90 34542810-7 2021 However, nitrate could increase cisplatin chemosensitivity, reduce its REDD1 expression, and attenuate AKT signaling activation in OSCC cells. Nitrates 9-16 DNA damage inducible transcript 4 Homo sapiens 71-76 34542810-7 2021 However, nitrate could increase cisplatin chemosensitivity, reduce its REDD1 expression, and attenuate AKT signaling activation in OSCC cells. Nitrates 9-16 AKT serine/threonine kinase 1 Homo sapiens 103-106 34182389-3 2021 This study examined both the long-term trends in atmospheric nitrogen (N) deposition from the 1990s to the 2010s and the response of stream water nitrate (NO3-) leaching from forested areas in western Japan. Nitrates 146-153 NBL1, DAN family BMP antagonist Homo sapiens 155-158 34643825-0 2021 Long-term variation of nitrate in the East Sea, Korea. Nitrates 23-30 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 43-46 34643825-7 2021 Second, decrease in the nitrate flux of the Nakdong River"s estuary due to the construction of the estuary dam and sewer treatment plant could also be a factor for the nitrate decrease in the East Sea. Nitrates 24-31 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 197-200 34643825-7 2021 Second, decrease in the nitrate flux of the Nakdong River"s estuary due to the construction of the estuary dam and sewer treatment plant could also be a factor for the nitrate decrease in the East Sea. Nitrates 168-175 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 197-200 34643825-9 2021 The amount of nitrate runoff reduced by the anthropogenic activities influenced the nitrate levels over a long period by the flow of currents in the East Sea. Nitrates 14-21 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 154-157 34643825-9 2021 The amount of nitrate runoff reduced by the anthropogenic activities influenced the nitrate levels over a long period by the flow of currents in the East Sea. Nitrates 84-91 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 154-157 34581118-14 2021 The delineation of NO3-type waters, especially the low-TDS type, is helpful for identifying groundwaters posing greater risks for human activities, and those with low nitrate concentrations but potential pollution risk, which is of great significance in the prevention and control of groundwater pollution. Nitrates 167-174 NBL1, DAN family BMP antagonist Homo sapiens 19-22 34180337-8 2021 The arabidopsis nitrate regulated1 (ANR1) is induced from the endosome by the Ca2+-CPKs-NLPs signaling pathway activated by the unphosphorylated form of NRT1.1 (NRT1.1 T101A) at high nitrate condition. Nitrates 183-190 AGAMOUS-like 44 Arabidopsis thaliana 36-40 34180337-8 2021 The arabidopsis nitrate regulated1 (ANR1) is induced from the endosome by the Ca2+-CPKs-NLPs signaling pathway activated by the unphosphorylated form of NRT1.1 (NRT1.1 T101A) at high nitrate condition. Nitrates 183-190 nitrate transporter 1.1 Arabidopsis thaliana 153-159 34180337-8 2021 The arabidopsis nitrate regulated1 (ANR1) is induced from the endosome by the Ca2+-CPKs-NLPs signaling pathway activated by the unphosphorylated form of NRT1.1 (NRT1.1 T101A) at high nitrate condition. Nitrates 183-190 nitrate transporter 1.1 Arabidopsis thaliana 161-165 34856430-6 2021 A new conversion mechanism was proposed that CN- was activated into electron-deficient cyanide radical ( CN) by OH, and then the CN intermediates reacted with O2- via nucleophilic addition to quickly form NO3-, preventing the formation of CNO- and promoting the mineralization of cyanide. Nitrates 208-212 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 242-245 34328901-0 2021 Mix-cultured aerobic denitrifying bacterial communities reduce nitrate: Novel insights in micro-polluted water treatment at lower temperature. Nitrates 63-70 Mix paired-like homeobox Homo sapiens 0-3 34800458-7 2022 In wintertime, maximum nitrate concentrations (up to 73 mg NO3/L) and loads (up to 1300 t NO3/a; up to 98% in winter) correlate with high-flow conditions. Nitrates 23-30 NBL1, DAN family BMP antagonist Homo sapiens 59-64 34352479-3 2021 Moreover, the hydrochemical parameters and the delta15N and delta18O values of nitrate were employed to quantitatively trace the sources and biochemical transformation of NO3-, and the contribution ratios of different NO3- sources were estimated using the stable isotope analysis in R based on the Bayesian model. Nitrates 79-86 NBL1, DAN family BMP antagonist Homo sapiens 171-174 34252777-4 2021 DON<1kDa dominated the DON pool and significantly correlated inversely with DIN, indicating the DON<1kDa mineralized into nitrate. Nitrates 122-129 neuregulin 2 Homo sapiens 96-101 34328950-1 2021 Nitrate (NO3) radical is an important oxidant in the atmosphere as it regulates the NOx budget and impacts secondary pollutant formation. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34328950-5 2021 Specifically, for the N2O5 uptake, the rapid increase in NO3 production, or to some extent, NO3 oxidation capacity, far outweighed the negative shift effect, leading to a net enhancement of N2O5 uptake in winter, which indicates that the action policy implemented led to an adverse effect on particulate nitrate formation via N2O5 uptake in winter. Nitrates 304-311 NBL1, DAN family BMP antagonist Homo sapiens 57-60 34328950-5 2021 Specifically, for the N2O5 uptake, the rapid increase in NO3 production, or to some extent, NO3 oxidation capacity, far outweighed the negative shift effect, leading to a net enhancement of N2O5 uptake in winter, which indicates that the action policy implemented led to an adverse effect on particulate nitrate formation via N2O5 uptake in winter. Nitrates 304-311 NBL1, DAN family BMP antagonist Homo sapiens 92-95 34767107-6 2021 Nitrate concentrations in the rural and urban areas were within 0.4-137 mg/L NO3- and 2.9-209 mg/L NO3-, respectively. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 77-80 34767107-6 2021 Nitrate concentrations in the rural and urban areas were within 0.4-137 mg/L NO3- and 2.9-209 mg/L NO3-, respectively. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 99-102 34764268-8 2021 These inhibitory impacts of nitrate on symbiosis occur in a Nlp1 and Nlp4 dependent manner and contrast with the positive influence of nitrate on cytokinin biosynthesis that occurs in species that do not form symbiotic root nodules. Nitrates 28-35 NLP1 Lotus japonicus 60-64 34677563-1 2021 High-quality CoP nanorings (CoP NRs) are easily achieved using a phosphorating treatment of CoOOH nanorings, and reveal high activity towards the hydrogen evolution reaction and the nitrate electrocatalytic reduction reaction due to substantial coordinately unsaturated active sites, a high surface area, and available mass transfer pathways. Nitrates 182-189 caspase recruitment domain family member 16 Homo sapiens 13-16 34618046-0 2021 CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth. Nitrates 49-56 calmodulin-like 38 Arabidopsis thaliana 0-18 34618046-0 2021 CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth. Nitrates 49-56 PEP1 receptor 2 Arabidopsis thaliana 23-38 34618046-3 2021 Here, we show that CALMODULIN-LIKE-38 (CML38), a calmodulin-like protein, specifically interacts with the PEP1 RECEPTOR 2 (PEPR2), and negatively regulates root elongation in Arabidopsis (Arabidopsis thaliana) in response to low nitrate (LN). Nitrates 229-236 calmodulin-like 38 Arabidopsis thaliana 19-37 34618046-3 2021 Here, we show that CALMODULIN-LIKE-38 (CML38), a calmodulin-like protein, specifically interacts with the PEP1 RECEPTOR 2 (PEPR2), and negatively regulates root elongation in Arabidopsis (Arabidopsis thaliana) in response to low nitrate (LN). Nitrates 229-236 calmodulin-like 38 Arabidopsis thaliana 39-44 34618046-3 2021 Here, we show that CALMODULIN-LIKE-38 (CML38), a calmodulin-like protein, specifically interacts with the PEP1 RECEPTOR 2 (PEPR2), and negatively regulates root elongation in Arabidopsis (Arabidopsis thaliana) in response to low nitrate (LN). Nitrates 229-236 PEP1 receptor 2 Arabidopsis thaliana 106-121 34618046-3 2021 Here, we show that CALMODULIN-LIKE-38 (CML38), a calmodulin-like protein, specifically interacts with the PEP1 RECEPTOR 2 (PEPR2), and negatively regulates root elongation in Arabidopsis (Arabidopsis thaliana) in response to low nitrate (LN). Nitrates 229-236 PEP1 receptor 2 Arabidopsis thaliana 123-128 34618046-4 2021 CML38 and PEPR2 are transcriptionally induced by treatments of exogenous nitrate and BR. Nitrates 73-80 calmodulin-like 38 Arabidopsis thaliana 0-5 34618046-4 2021 CML38 and PEPR2 are transcriptionally induced by treatments of exogenous nitrate and BR. Nitrates 73-80 PEP1 receptor 2 Arabidopsis thaliana 10-15 34523752-6 2021 Sequence analysis revealed three sub-types of AtNPF6.3 orthologs based on their predicted substrate-binding residues: A (chloride selective), B (nitrate selective), and C (legume specific). Nitrates 145-152 nitrate transporter 1.1 Arabidopsis thaliana 46-54 34649677-0 2021 What is the role of the nitrate reductase (euknr) gene in fungi that live in nitrate-free environments? Nitrates 77-84 AWN88_RS04670 Agrobacterium tumefaciens 24-41 34558591-1 2021 A procedure for the formation of a nitrate-encapsulating tripalladium(II) cage via self-assembly of Pd(NO3)2 with 1,3-bis(dimethyl(pyridin-4-yl)silyl)propane (L) was developed. Nitrates 35-42 NBL1, DAN family BMP antagonist Homo sapiens 103-106 34558591-2 2021 The self-assembly reaction initially produces spiro-type macrocycles, PdL2, and finally results in transformation into a nitrate-encapsulated cage, ((NO3)@Pd3L6), in the mother liquor. Nitrates 121-128 programmed cell death 1 ligand 2 Homo sapiens 70-74 34558591-2 2021 The self-assembly reaction initially produces spiro-type macrocycles, PdL2, and finally results in transformation into a nitrate-encapsulated cage, ((NO3)@Pd3L6), in the mother liquor. Nitrates 121-128 NBL1, DAN family BMP antagonist Homo sapiens 150-153 34657263-1 2022 High concentration of nitrate (NO3-) in groundwater is a major concern because of its complex origin and harmful effects on human health. Nitrates 22-29 NBL1, DAN family BMP antagonist Homo sapiens 31-34 34147777-3 2021 The results revealed that the nitrate accumulation at 0-100 cm, 100-200 cm, 200-300 cm, and >300 cm were 504, 390, 349, and 244 kg N ha-1, with accumulation rates of 62, 54, 19, and 16 kg N ha-1 yr-1 for plastic greenhouse vegetables (PG); for open field vegetables (OF), they were 264, 217, 228, and 242 kg N ha-1 with accumulation rates of 26, 24, 18, and 10 kg N ha-1 yr-1, respectively. Nitrates 30-37 solute carrier family 9 member B1 Homo sapiens 131-137 34147777-3 2021 The results revealed that the nitrate accumulation at 0-100 cm, 100-200 cm, 200-300 cm, and >300 cm were 504, 390, 349, and 244 kg N ha-1, with accumulation rates of 62, 54, 19, and 16 kg N ha-1 yr-1 for plastic greenhouse vegetables (PG); for open field vegetables (OF), they were 264, 217, 228, and 242 kg N ha-1 with accumulation rates of 26, 24, 18, and 10 kg N ha-1 yr-1, respectively. Nitrates 30-37 solute carrier family 9 member B1 Homo sapiens 188-199 34147777-3 2021 The results revealed that the nitrate accumulation at 0-100 cm, 100-200 cm, 200-300 cm, and >300 cm were 504, 390, 349, and 244 kg N ha-1, with accumulation rates of 62, 54, 19, and 16 kg N ha-1 yr-1 for plastic greenhouse vegetables (PG); for open field vegetables (OF), they were 264, 217, 228, and 242 kg N ha-1 with accumulation rates of 26, 24, 18, and 10 kg N ha-1 yr-1, respectively. Nitrates 30-37 solute carrier family 9 member B1 Homo sapiens 308-314 34147777-3 2021 The results revealed that the nitrate accumulation at 0-100 cm, 100-200 cm, 200-300 cm, and >300 cm were 504, 390, 349, and 244 kg N ha-1, with accumulation rates of 62, 54, 19, and 16 kg N ha-1 yr-1 for plastic greenhouse vegetables (PG); for open field vegetables (OF), they were 264, 217, 228, and 242 kg N ha-1 with accumulation rates of 26, 24, 18, and 10 kg N ha-1 yr-1, respectively. Nitrates 30-37 solute carrier family 9 member B1 Homo sapiens 364-375 34677535-0 2021 A Study to Enhance the Nitrate-Nitrogen Removal Rate without Dismantling the NF Module by Building a PFSA Ionomer-Coated NF Module. Nitrates 23-30 neurofascin Homo sapiens 121-123 34228952-9 2021 Moreover, the catalyst D-Pd1/Sn1 reached a complete nitrate removal in the municipal wastewater treatment plant effluent water within 3 h. The results provide a prospect for denitrification in biological wastewater treatment plants. Nitrates 52-59 transforming growth factor beta 1 Homo sapiens 23-28 34228952-9 2021 Moreover, the catalyst D-Pd1/Sn1 reached a complete nitrate removal in the municipal wastewater treatment plant effluent water within 3 h. The results provide a prospect for denitrification in biological wastewater treatment plants. Nitrates 52-59 solute carrier family 38 member 3 Homo sapiens 29-32 34087531-1 2021 Transport and transformation processes of nitrogen in the soil are an essential part of understanding the relationship between agricultural input and nitrate (NO3-) concentrations in groundwater. Nitrates 150-157 NBL1, DAN family BMP antagonist Homo sapiens 159-162 34129038-3 2021 Here, we showed that the growth-related transcription factors HOMOLOG OF BRASSINOSTEROID ENHANCED EXPRESSION2 INTERACTING WITH IBH1 (HBI1) and its three closest homologs (HBIs) positively regulate nitrate signaling in Arabidopsis thaliana. Nitrates 197-204 ILI1 binding bHLH 1 Arabidopsis thaliana 127-131 34679685-1 2021 The depletion of nitrate and nitrite, stable nitric oxide (NO) end-products, promotes adipose tissue dysfunction and insulin resistance (IR). Nitrates 17-24 insulin Homo sapiens 117-124 34679685-6 2021 Plasma nitrate, but not nitrite, correlated positively with vegetable intake (r = 0.38, p = 0.018) and was inversely associated with HOMA-IR (r = -0.44, p = 0.006), BMI (r = -0.35, p = 0.028), GGT (r = -0.37, p = 0.019) and CRP (r = -0.34, p = 0.034). Nitrates 7-14 gamma-glutamyltransferase light chain family member 3 Homo sapiens 193-196 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 0-7 solute carrier family 17 member 5 Homo sapiens 23-29 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 0-7 solute carrier family 17 member 5 Homo sapiens 115-121 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 107-114 solute carrier family 17 member 5 Homo sapiens 23-29 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 107-114 solute carrier family 17 member 5 Homo sapiens 115-121 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 153-160 solute carrier family 17 member 5 Homo sapiens 23-29 34581269-5 2021 Nitrate could increase sialin expression, a nitrate transporter expressed in the parotid gland, making the nitrate-sialin feedback loop that facilitates nitrate influx into cells for maintaining cell proliferation and inhibiting apoptosis. Nitrates 153-160 solute carrier family 17 member 5 Homo sapiens 115-121 34581269-6 2021 Furthermore, nitrate enhanced cell proliferation via the epidermal growth factor receptor (EGFR)-protein kinase B (AKT)-mitogen-activated protein kinase (MAPK) signaling pathway in irradiated parotid gland tissue. Nitrates 13-20 epidermal growth factor receptor Homo sapiens 57-89 34581269-6 2021 Furthermore, nitrate enhanced cell proliferation via the epidermal growth factor receptor (EGFR)-protein kinase B (AKT)-mitogen-activated protein kinase (MAPK) signaling pathway in irradiated parotid gland tissue. Nitrates 13-20 epidermal growth factor receptor Homo sapiens 91-95 34581269-6 2021 Furthermore, nitrate enhanced cell proliferation via the epidermal growth factor receptor (EGFR)-protein kinase B (AKT)-mitogen-activated protein kinase (MAPK) signaling pathway in irradiated parotid gland tissue. Nitrates 13-20 protein tyrosine kinase 2 beta Homo sapiens 97-113 34581269-6 2021 Furthermore, nitrate enhanced cell proliferation via the epidermal growth factor receptor (EGFR)-protein kinase B (AKT)-mitogen-activated protein kinase (MAPK) signaling pathway in irradiated parotid gland tissue. Nitrates 13-20 AKT serine/threonine kinase 1 Homo sapiens 115-118 34581269-7 2021 Collectively, nitrate effectively prevented IR-induced xerostomia via the EGFR-AKT-MAPK signaling pathway. Nitrates 14-21 epidermal growth factor receptor Homo sapiens 74-78 34581269-7 2021 Collectively, nitrate effectively prevented IR-induced xerostomia via the EGFR-AKT-MAPK signaling pathway. Nitrates 14-21 AKT serine/threonine kinase 1 Homo sapiens 79-82 34129038-3 2021 Here, we showed that the growth-related transcription factors HOMOLOG OF BRASSINOSTEROID ENHANCED EXPRESSION2 INTERACTING WITH IBH1 (HBI1) and its three closest homologs (HBIs) positively regulate nitrate signaling in Arabidopsis thaliana. Nitrates 197-204 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 133-137 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 27-34 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 0-4 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 27-34 Plant regulator RWP-RK family protein Arabidopsis thaliana 43-47 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 27-34 NIN like protein 7 Arabidopsis thaliana 52-56 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 89-96 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 0-4 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 89-96 Plant regulator RWP-RK family protein Arabidopsis thaliana 43-47 34129038-4 2021 HBI1 is rapidly induced by nitrate through NLP6 and NLP7, which are master regulators of nitrate signaling. Nitrates 89-96 NIN like protein 7 Arabidopsis thaliana 52-56 34129038-7 2021 Nitrate treatment induces the nuclear localization of NLP7, whereas such promoting effects of nitrate are significantly impaired in the hbi-q and cat2 cat3 mutants, which accumulate high levels of H2O2. Nitrates 0-7 NIN like protein 7 Arabidopsis thaliana 54-58 34129038-7 2021 Nitrate treatment induces the nuclear localization of NLP7, whereas such promoting effects of nitrate are significantly impaired in the hbi-q and cat2 cat3 mutants, which accumulate high levels of H2O2. Nitrates 94-101 NIN like protein 7 Arabidopsis thaliana 54-58 34129038-7 2021 Nitrate treatment induces the nuclear localization of NLP7, whereas such promoting effects of nitrate are significantly impaired in the hbi-q and cat2 cat3 mutants, which accumulate high levels of H2O2. Nitrates 94-101 cationic amino acid transporter 2 Arabidopsis thaliana 146-150 34129038-7 2021 Nitrate treatment induces the nuclear localization of NLP7, whereas such promoting effects of nitrate are significantly impaired in the hbi-q and cat2 cat3 mutants, which accumulate high levels of H2O2. Nitrates 94-101 catalase 3 Arabidopsis thaliana 151-155 34129038-8 2021 These results demonstrate that HBI-mediated ROS homeostasis regulates nitrate signal transduction through modulating the nucleocytoplasmic shuttling of NLP7. Nitrates 70-77 NIN like protein 7 Arabidopsis thaliana 152-156 34528820-0 2021 Genome Sequence of Linnemannia hyalina Strain SCG-10, a Cold-Adapted and Nitrate-Reducing Fungus Isolated from Cornfield Soil in Minnesota, USA. Nitrates 73-80 stathmin 2 Homo sapiens 46-52 34549237-1 2021 Through the combination of X-ray structure analysis and density functional theory (DFT) theoretical calculations at the B3LYP-D3/def2-TZVP level of theory, we designed and investigated two novel host units for the recognition of neutral (e.g. halobenzenes) and charged (e.g. chloride and nitrate) guests inspired by a glutamate carboxypeptidase II (GCPII) system and its inhibitors. Nitrates 288-295 folate hydrolase 1 Homo sapiens 318-347 34549237-1 2021 Through the combination of X-ray structure analysis and density functional theory (DFT) theoretical calculations at the B3LYP-D3/def2-TZVP level of theory, we designed and investigated two novel host units for the recognition of neutral (e.g. halobenzenes) and charged (e.g. chloride and nitrate) guests inspired by a glutamate carboxypeptidase II (GCPII) system and its inhibitors. Nitrates 288-295 folate hydrolase 1 Homo sapiens 349-354 34528820-1 2021 We report here the genome sequence of Linnemannia hyalina strain SCG-10, a cold-adapted and nitrate-reducing fungus isolated from soil. Nitrates 92-99 stathmin 2 Homo sapiens 65-71 34147727-8 2021 Nitrate decrease MDA by reducing the activities of superoxide dismutase, peroxidase, and catalase in root of the N-efficient genotype. Nitrates 0-7 peroxidase A2 Brassica napus 73-83 34519758-0 2021 Electrocatalytic nitrate reduction with Co-based catalysts: comparison of DIM, TIM and cyclam ligands. Nitrates 17-24 Rho guanine nucleotide exchange factor 5 Homo sapiens 79-82 34357701-0 2021 Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture. Nitrates 0-7 Auxin efflux carrier family protein Arabidopsis thaliana 48-52 34357701-6 2021 The phosphorylation profile of NITRATE TRANSPORTER 1.1 (NRT1.1) mutant plants was significantly altered as compared to wild-type plants, confirming its key role in nitrate signaling pathways that involves phosphorylation changes. Nitrates 164-171 nitrate transporter 1.1 Arabidopsis thaliana 31-54 34357701-6 2021 The phosphorylation profile of NITRATE TRANSPORTER 1.1 (NRT1.1) mutant plants was significantly altered as compared to wild-type plants, confirming its key role in nitrate signaling pathways that involves phosphorylation changes. Nitrates 164-171 nitrate transporter 1.1 Arabidopsis thaliana 56-62 34357701-8 2021 We validated a new phosphorylation site in PIN2 and provide evidence that it functions in primary and lateral root growth responses to nitrate. Nitrates 135-142 Auxin efflux carrier family protein Arabidopsis thaliana 43-47 34089542-3 2021 By investigating moss N contents and delta15 N values in southwestern China in 1954-1964, 1970-1994, and 2005-2015, we reconstructed fluxes and source contributions of atmospheric ammonium (NH4 + ) and nitrate (NO3 - ) deposition and their historical changes. Nitrates 202-209 NBL1, DAN family BMP antagonist Homo sapiens 211-214 34155644-5 2021 Also, dissolution - being microbially-mediated - would be buffered by the presence of nitrate (NO3 - ), which is a preferable electron acceptor than Fe and Mn in microbial reactions. Nitrates 86-93 NBL1, DAN family BMP antagonist Homo sapiens 95-98 34147727-8 2021 Nitrate decrease MDA by reducing the activities of superoxide dismutase, peroxidase, and catalase in root of the N-efficient genotype. Nitrates 0-7 catalase-3-like Brassica napus 89-97 34198052-5 2021 At long-term, nitrate reductase (SlNR) and nitrite reductase (SlNIR) expression were not significantly different between nitrate treatments in RO, while significantly down-regulated under nitrate limiting treatment in UC82. Nitrates 188-195 nitrite reductase Solanum lycopersicum 43-60 34074412-5 2021 In order to demonstrate applicability of the method, label free SERS measurements of nitrate ion was performed on the proposed sensing platform. Nitrates 85-92 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 64-68 34578546-2 2021 In this paper, Sm3+ and Nd3+ co-doped CeO2 (SNDC) and pure CeO2 are synthesized via glycine-nitrate process (GNP) and the electro-chemical properties of the nanocrystalline structure electrolyte are investigated using complementary techniques. Nitrates 92-99 mitochondrially encoded NADH dehydrogenase 3 Homo sapiens 24-27 34477653-3 2021 In this study, a novel zeolitic imidazolate framework-8 film engineered bismuth nanosheet electrocatalyst (ZIF-8/Bi-CC) was designed and synthesized for the electrochemical reduction of nitrate. Nitrates 186-193 Bicaudal C Drosophila melanogaster 113-118 34477653-7 2021 More importantly, the final nitrate removal rate of ZIF-8/Bi-CC was close to 90% after 5 h when treating actual garbage fly ash wastewater, the NITRR efficiency stability and the obtained product were confirmed by five electrochemical cycles. Nitrates 28-35 Bicaudal C Drosophila melanogaster 58-63 34410136-1 2021 Nitrate (NO3-) reduction reaction (NtRR) is considered as a green alternative method for the conventional method of NH3 synthesis (Haber-Bosch process), which is known as a high energy consuming and large CO2 emitting process. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34264986-10 2021 By adding supplementary LED lamps into the EAS, the soluble sugar content of lettuce increased by 72.14% and the nitrate content of lettuce decreased by 21.51%. Nitrates 113-120 small integral membrane protein 10 like 2A Homo sapiens 24-27 34075592-3 2021 This raises the question of why nitrate may or may not be present in phloem sap, why its concentration is generally kept low, and whether plant shoot-root nutrient cycling also involves nitrate. Nitrates 32-39 SH2 domain containing 1A Homo sapiens 76-79 34408222-1 2021 Nitrate (NO3-) pollution is a serious global problem, and the quantitative analysis of its sources contributions is essential for devising effective water-related environmental-protection policies. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34161745-8 2021 The nitrate group showed significantly increased serum nitrate/nitrite (Delta1.32muM), increased brachial and popliteal FMD (Delta1.3% and Delta1.7%, respectively), reduced peripheral and central systolic BP (Delta-4.7mmHg and Delta-8.2mmHg, respectively), increased maximal walking distance (Delta92.7m) and time (Delta56.3s), and reduced deoxygenated hemoglobin during walking. Nitrates 4-11 delta like non-canonical Notch ligand 1 Homo sapiens 72-78 34161745-8 2021 The nitrate group showed significantly increased serum nitrate/nitrite (Delta1.32muM), increased brachial and popliteal FMD (Delta1.3% and Delta1.7%, respectively), reduced peripheral and central systolic BP (Delta-4.7mmHg and Delta-8.2mmHg, respectively), increased maximal walking distance (Delta92.7m) and time (Delta56.3s), and reduced deoxygenated hemoglobin during walking. Nitrates 4-11 delta like non-canonical Notch ligand 1 Homo sapiens 125-131 34161745-8 2021 The nitrate group showed significantly increased serum nitrate/nitrite (Delta1.32muM), increased brachial and popliteal FMD (Delta1.3% and Delta1.7%, respectively), reduced peripheral and central systolic BP (Delta-4.7mmHg and Delta-8.2mmHg, respectively), increased maximal walking distance (Delta92.7m) and time (Delta56.3s), and reduced deoxygenated hemoglobin during walking. Nitrates 4-11 delta like non-canonical Notch ligand 1 Homo sapiens 139-145 34497626-0 2021 NRT1.1 Dual-Affinity Nitrate Transport/Signalling and its Roles in Plant Abiotic Stress Resistance. Nitrates 21-28 immunoglobulin superfamily member 9 Homo sapiens 0-4 34421841-1 2021 Woodchip bioreactors are increasingly used to remove nitrate (NO3 -) from agricultural drainage water in order to protect aquatic ecosystems from excess nitrogen. Nitrates 53-60 NBL1, DAN family BMP antagonist Homo sapiens 62-65 34440751-7 2021 The current literature suggests that ROS/RNS nitrate proNGF and reduce the expression of the proNGF receptor tropomyosin-related kinase A (TrkA), disrupting its downstream survival signalling. Nitrates 45-52 neurotrophic receptor tyrosine kinase 1 Homo sapiens 139-143 34309015-6 2021 In mouse models of cardiac remodelling, we also show that restoration of circulating nitrite levels using dietary nitrate improves endothelial dysfunction through targeting of xanthine oxidoreductase (XOR)-driven H2 O2 and superoxide, and reduces cardiac fibrosis through NO-mediated block of SMAD-phosphorylation leading to improvements in cardiac structure and function. Nitrates 114-121 xanthine dehydrogenase Mus musculus 176-199 34309015-6 2021 In mouse models of cardiac remodelling, we also show that restoration of circulating nitrite levels using dietary nitrate improves endothelial dysfunction through targeting of xanthine oxidoreductase (XOR)-driven H2 O2 and superoxide, and reduces cardiac fibrosis through NO-mediated block of SMAD-phosphorylation leading to improvements in cardiac structure and function. Nitrates 114-121 xanthine dehydrogenase Mus musculus 201-204 34276717-0 2021 Growth Performance Can Be Increased Under High Nitrate and High Salt Stress Through Enhanced Nitrate Reductase Activity in Arabidopsis Anthocyanin Over-Producing Mutant Plants. Nitrates 47-54 nitrate reductase 1 Arabidopsis thaliana 93-110 34276717-3 2021 However, excessive nitrogen use has an enormous negative impact on ecosystems and human health through the emission of intense greenhouse gases, such as nitric oxide derived from the nitrate (NO3 -) assimilation cascade. Nitrates 183-190 NBL1, DAN family BMP antagonist Homo sapiens 192-195 34124878-0 2021 Synergistic Effect of Co(III) and Co(II) in a 3D Structured Co3O4/Carbon Felt Electrode for Enhanced Electrochemical Nitrate Reduction Reaction. Nitrates 117-124 mitochondrially encoded cytochrome c oxidase III Homo sapiens 22-29 34209142-1 2021 The objective of the study was to gather insight into the metabolism of lead-removing microorganisms, coupled with Pb(II) removal, biomass viability and nitrate concentrations for Pb(II) bioremoval using an industrially obtained microbial consortium. Nitrates 153-160 submaxillary gland androgen regulated protein 3B Homo sapiens 180-186 34124878-0 2021 Synergistic Effect of Co(III) and Co(II) in a 3D Structured Co3O4/Carbon Felt Electrode for Enhanced Electrochemical Nitrate Reduction Reaction. Nitrates 117-124 mitochondrially encoded cytochrome c oxidase II Homo sapiens 34-40 34086442-4 2021 The uptake process of NO2 on OA gives HONO as a reaction product, and the highest HONO production was observed upon the heterogeneous reaction of NO2 with OA in the presence of nitrate (NO3-) ions. Nitrates 177-184 NBL1, DAN family BMP antagonist Homo sapiens 186-189 34235267-1 2021 A combined technique of production and storage of ammonia (NH3) from electroreduction of nitrate (NO3 -) through one material is highly desirable but remains a huge challenge. Nitrates 89-96 NBL1, DAN family BMP antagonist Homo sapiens 98-101 34207422-1 2021 Denitrifying woodchip bioreactors (WBR), which aim to reduce nitrate (NO3-) pollution from agricultural drainage water, are less efficient when cold temperatures slow down the microbial transformation processes. Nitrates 61-68 NBL1, DAN family BMP antagonist Homo sapiens 70-73 34208733-1 2021 A direct, reagent-free, ultraviolet spectroscopic method for the simultaneous determination of nitrate (NO3-), nitrite (NO2-), and salinity in seawater is presented. Nitrates 95-102 NBL1, DAN family BMP antagonist Homo sapiens 104-107 34198661-4 2021 The intake of nitrate increased the nitrate plus nitrite plasma levels about 8-fold and induced the upregulation of catalase, superoxide dismutase, glutathione peroxidase, mitofusin 2 and PGC1alpha in PBMCs after exercise. Nitrates 14-21 catalase Homo sapiens 116-124 34198661-4 2021 The intake of nitrate increased the nitrate plus nitrite plasma levels about 8-fold and induced the upregulation of catalase, superoxide dismutase, glutathione peroxidase, mitofusin 2 and PGC1alpha in PBMCs after exercise. Nitrates 14-21 mitofusin 2 Homo sapiens 172-183 34198661-4 2021 The intake of nitrate increased the nitrate plus nitrite plasma levels about 8-fold and induced the upregulation of catalase, superoxide dismutase, glutathione peroxidase, mitofusin 2 and PGC1alpha in PBMCs after exercise. Nitrates 14-21 PPARG coactivator 1 alpha Homo sapiens 188-197 34198661-5 2021 The gene expression of catalase and TNFalpha was enhanced by phorbol myristate acetate (PMA) only in the placebo group, while the glutathione peroxidase expression was enhanced by PMA only after nitrate intake. Nitrates 195-202 catalase Homo sapiens 23-31 34198661-5 2021 The gene expression of catalase and TNFalpha was enhanced by phorbol myristate acetate (PMA) only in the placebo group, while the glutathione peroxidase expression was enhanced by PMA only after nitrate intake. Nitrates 195-202 tumor necrosis factor Homo sapiens 36-44 35227848-1 2022 Nitrate (NO3-) pollution in water bodies has received widespread attention, but studies on nitrogen transformation and pollution risk assessment are still limited, especially in rare earth mining areas. Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 9-12 34114114-11 2021 With a combined change in climate and land cover, the annual nitrate concentrations are expected to increase by + 19.7% and + 17.9%, under RCP 4.5 and RCP 8.5, respectively. Nitrates 61-68 CGRP receptor component Homo sapiens 139-142 34114114-11 2021 With a combined change in climate and land cover, the annual nitrate concentrations are expected to increase by + 19.7% and + 17.9%, under RCP 4.5 and RCP 8.5, respectively. Nitrates 61-68 CGRP receptor component Homo sapiens 151-154 35525348-3 2022 Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process. Nitrates 32-39 NBL1, DAN family BMP antagonist Homo sapiens 71-74 35525348-3 2022 Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process. Nitrates 107-114 NBL1, DAN family BMP antagonist Homo sapiens 71-74 35525348-3 2022 Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process. Nitrates 107-114 NBL1, DAN family BMP antagonist Homo sapiens 89-92 35525348-3 2022 Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process. Nitrates 107-114 NBL1, DAN family BMP antagonist Homo sapiens 116-119 35525348-3 2022 Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process. Nitrates 107-114 NBL1, DAN family BMP antagonist Homo sapiens 319-322 35576711-1 2022 Researchers have long been committed to identify nitrate sources in groundwater and to develop an advanced technique for its remediation because better apply remediation solution and management of water quality is highly dependent on the identification of the NO3- sources contamination in water. Nitrates 49-56 NBL1, DAN family BMP antagonist Homo sapiens 260-263 35472551-8 2022 CSCF exhibited good photocatalytic degradation performance in a broad range of ionic strengths, in the presence of common coexisting ions including Cl-, NO3- and SO42-, in a wide range of pH (5-11), and in real water samples including tap water, river water and lake water. Nitrates 153-157 mitogen-activated protein kinase kinase kinase 7 Homo sapiens 0-4 35472839-0 2022 APCS-MLR model: A convenient and fast method for quantitative identification of nitrate pollution sources in groundwater. Nitrates 80-87 amyloid P component, serum Homo sapiens 0-4 35271927-5 2022 We quantified the effects of colder, surface water temperature on the nitrate (NO3-) reduction rate in vegetated marsh and open water bay sediments. Nitrates 70-77 NBL1, DAN family BMP antagonist Homo sapiens 79-82 35202681-4 2022 Five years (2015-2020) of water quantity and quality data from 11 agricultural watersheds in southern Ontario were used to develop GAMs to predict total phosphorus (TP) and nitrate (NO3-) loads. Nitrates 173-180 NBL1, DAN family BMP antagonist Homo sapiens 182-185 35157864-5 2022 Transcriptome analysis of mouse lungs exposed to nitrate/sulfate aerosols reveals interferon gamma-associated immune response. Nitrates 49-56 interferon gamma Mus musculus 82-98 35568027-4 2022 Surprisingly, avirulent S. Typhimurium was shown to be unable to utilize epithelial-derived nitrate because its chemotaxis receptors McpB and McpC exclude the pathogen from the niche occupied by E. coli. Nitrates 92-99 hlyB-like ABC transporter-like protein Escherichia coli 133-137 35019185-3 2022 Simulated fluxes include microbial immobilization and plant uptake, which compete with nitrification and denitrification, respectively, for available soil ammonium (NH4 + ) and nitrate (NO3 - ). Nitrates 177-184 NBL1, DAN family BMP antagonist Homo sapiens 186-189 34193742-3 2021 However, NO is divided into two fractions, nitrite (NO2) and nitrate (NO3), which appear to play different roles in epileptogenesis. Nitrates 61-68 NBL1, DAN family BMP antagonist Mus musculus 70-73 34275783-1 2021 To investigate the effects of hydralazine combined with nitrate on serum levels of Adropin and brain natriuretic peptide (BNP), left ventricular remodeling and prognosis in patients with chronic heart failure (CHF). Nitrates 56-63 energy homeostasis associated Homo sapiens 83-90 34275783-1 2021 To investigate the effects of hydralazine combined with nitrate on serum levels of Adropin and brain natriuretic peptide (BNP), left ventricular remodeling and prognosis in patients with chronic heart failure (CHF). Nitrates 56-63 natriuretic peptide B Homo sapiens 95-120 34275783-1 2021 To investigate the effects of hydralazine combined with nitrate on serum levels of Adropin and brain natriuretic peptide (BNP), left ventricular remodeling and prognosis in patients with chronic heart failure (CHF). Nitrates 56-63 natriuretic peptide B Homo sapiens 122-125 34264555-3 2021 The aim of the work was to study the levels of nitrate contamination of CP and assess the associated risk to the health of children and adults in the Baikal Region. Nitrates 47-54 ceruloplasmin Homo sapiens 72-74 35243632-0 2022 NLP1 binds the CEP1 signalling peptide promoter to repress its expression in response to nitrate. Nitrates 89-96 nucleoporin 42 Homo sapiens 0-4 35243632-0 2022 NLP1 binds the CEP1 signalling peptide promoter to repress its expression in response to nitrate. Nitrates 89-96 centriolin Homo sapiens 15-19 35150690-5 2022 The plotting of delta15N-NO3- versus NO3-/Cl- ratios also supported the assumption that sewage is the dominant nitrate source. Nitrates 111-118 NBL1, DAN family BMP antagonist Homo sapiens 37-40 35398714-5 2022 Consumption of nitrate partially preserved glucose tolerance and, within skeletal muscle, normalized insulin-induced Akt phosphorylation, mitochondrial ADP sensitivity, mtH2O2, protein carbonylation and global mitochondrial acetylation status. Nitrates 15-22 thymoma viral proto-oncogene 1 Mus musculus 117-120 35398714-6 2022 Nitrate also prevented the HFD-mediated reduction in SIRT1 protein, and interestingly, the positive effects of nitrate ingestion on glucose homeostasis and mitochondrial acetylation levels were abolished in SIRT1 inducible knock-out mice, suggesting SIRT1 is required for the beneficial effects of dietary nitrate. Nitrates 0-7 sirtuin 1 Mus musculus 53-58 35398714-6 2022 Nitrate also prevented the HFD-mediated reduction in SIRT1 protein, and interestingly, the positive effects of nitrate ingestion on glucose homeostasis and mitochondrial acetylation levels were abolished in SIRT1 inducible knock-out mice, suggesting SIRT1 is required for the beneficial effects of dietary nitrate. Nitrates 111-118 sirtuin 1 Mus musculus 53-58 35398714-6 2022 Nitrate also prevented the HFD-mediated reduction in SIRT1 protein, and interestingly, the positive effects of nitrate ingestion on glucose homeostasis and mitochondrial acetylation levels were abolished in SIRT1 inducible knock-out mice, suggesting SIRT1 is required for the beneficial effects of dietary nitrate. Nitrates 111-118 sirtuin 1 Mus musculus 207-212 35398714-6 2022 Nitrate also prevented the HFD-mediated reduction in SIRT1 protein, and interestingly, the positive effects of nitrate ingestion on glucose homeostasis and mitochondrial acetylation levels were abolished in SIRT1 inducible knock-out mice, suggesting SIRT1 is required for the beneficial effects of dietary nitrate. Nitrates 111-118 sirtuin 1 Mus musculus 250-255 35398714-7 2022 Altogether, dietary nitrate preserves mitochondrial ADP sensitivity and global lysine acetylation in HFD-fed mice, while in the absence of SIRT1, the effects of nitrate on glucose tolerance and mitochondrial acetylation were abrogated. Nitrates 161-168 sirtuin 1 Mus musculus 139-144 35421667-1 2022 If we can use toxic aromatic compounds as supplementary carbon source, the simultaneous removal of nitrate (NO3-) and aromatic compounds may be achieved at much lower chemical costs. Nitrates 99-106 NBL1, DAN family BMP antagonist Homo sapiens 108-111 35614500-1 2022 In this research, the possibility of using hydrogenated Dowex 50WX8 resin for the recovery and separation of Pr(III), Dy(III) and Y(III) from aqueous nitrate solutions were carried out. Nitrates 150-157 transmembrane protein 37 Homo sapiens 109-116 35614500-1 2022 In this research, the possibility of using hydrogenated Dowex 50WX8 resin for the recovery and separation of Pr(III), Dy(III) and Y(III) from aqueous nitrate solutions were carried out. Nitrates 150-157 transmembrane protein 37 Homo sapiens 121-124 35614500-1 2022 In this research, the possibility of using hydrogenated Dowex 50WX8 resin for the recovery and separation of Pr(III), Dy(III) and Y(III) from aqueous nitrate solutions were carried out. Nitrates 150-157 transmembrane protein 37 Homo sapiens 132-135 35604567-3 2022 Moreover, there is no consensus on the safe administration of dietary nitrate as an ergogenic aid. Nitrates 70-77 activation induced cytidine deaminase Homo sapiens 94-97 35604567-17 2022 The effects of dietary nitrate appear to be diminished in individuals with a higher aerobic fitness (peak oxygen consumption (VO2peak) > 60 ml/kg/min), and therefore, aerobic fitness should be taken into account when considering use of dietary nitrate as an ergogenic aid. Nitrates 23-30 activation induced cytidine deaminase Homo sapiens 268-271 35583665-2 2022 The global increases in the surface and groundwater nitrate (NO3 - ) concentrations due to synthetic fertilizer input have emerged as major sustainability threats to terrestrial and aquatic ecosystems. Nitrates 52-59 NBL1, DAN family BMP antagonist Homo sapiens 61-64 35579458-7 2022 Compared to oxic (>60 muM O2) Tara Ocean and high-hypoxic (>20 to <=60 muM O2) BoB samples, we found more SAR11-nar sequences (responsible for reducing nitrate to nitrite) in low-hypoxic (>5 to <=20 muM O2) BoB waters. Nitrates 152-159 G protein-coupled receptor 15 Homo sapiens 79-82 35579458-7 2022 Compared to oxic (>60 muM O2) Tara Ocean and high-hypoxic (>20 to <=60 muM O2) BoB samples, we found more SAR11-nar sequences (responsible for reducing nitrate to nitrite) in low-hypoxic (>5 to <=20 muM O2) BoB waters. Nitrates 152-159 G protein-coupled receptor 15 Homo sapiens 207-210 35579458-9 2022 It seems that the nitrite-N was not further reduced to nitrogen through denitrification but likely oxidized to nitrate by Nitrospinae in the BoB OMZ and then accumulated in the form of nitrate-N. Nitrates 111-118 G protein-coupled receptor 15 Homo sapiens 141-144 35579458-11 2022 Together, these results suggested that reduction of oxygen concentration and OMZ expansion may increase the use of nitrate by SAR11 and N2 production in the BoB. Nitrates 115-122 G protein-coupled receptor 15 Homo sapiens 157-160 35573269-6 2022 In particular, in the CS range from 0.02 to 0.03 s-1, the nitrate fraction was 17% on NPF event days and 26% on non-NPF event days. Nitrates 58-65 citrate synthase Homo sapiens 22-24 35351554-5 2022 Besides, the potential selecting advantage of nitrate reducing bacteria over nitrite reducing bacteria and the enrichment of dissimilatory nitrate reduction to ammonium (DNRA) bacteria could be responsible for the nitrite and ammonia accumulation at pH 3. Nitrates 46-53 phenylalanine hydroxylase Homo sapiens 250-252 35233916-3 2022 Herein, a modification of nitrate ion (NO3 - ) is proposed and validated to improve the homogeneity of the SEI in practical LMBs. Nitrates 26-33 NBL1, DAN family BMP antagonist Homo sapiens 39-42 35351554-5 2022 Besides, the potential selecting advantage of nitrate reducing bacteria over nitrite reducing bacteria and the enrichment of dissimilatory nitrate reduction to ammonium (DNRA) bacteria could be responsible for the nitrite and ammonia accumulation at pH 3. Nitrates 139-146 phenylalanine hydroxylase Homo sapiens 250-252 35149011-3 2022 The existence of nitrate in general decreased TCE dechlorination efficiency to varying degrees, and the higher nitrate concentration, the stronger the inhibitory effects, verified by the gradually decreased transcription levels of tceA. Nitrates 17-24 transcription elongation factor A1 Homo sapiens 231-235 35065174-0 2022 Enhanced bioremediation of RDX and Co-Contaminants perchlorate and nitrate using an anaerobic dehalogenating consortium in a fractured rock aquifer. Nitrates 67-74 radixin Homo sapiens 27-30 35065174-2 2022 Bioremediation of RDX is feasible through biostimulation of native microbes with an organic carbon donor but may be less efficient, or not occur at all, in the presence of the common co-contaminants perchlorate and nitrate. Nitrates 215-222 radixin Homo sapiens 18-21 35065174-7 2022 In microcosms with groundwater containing perchlorate and nitrate, RDX degradation began without delay when bioaugmented with 10% WBC-2. Nitrates 58-65 radixin Homo sapiens 67-70 35149011-3 2022 The existence of nitrate in general decreased TCE dechlorination efficiency to varying degrees, and the higher nitrate concentration, the stronger the inhibitory effects, verified by the gradually decreased transcription levels of tceA. Nitrates 111-118 transcription elongation factor A1 Homo sapiens 231-235 35192730-9 2022 The biopterin, BH4, and norepinephrine contents were increased in penile homogenates from BH4-supplemented Spr-/- mice, and the TH protein levels tended to increase, and their nitrite plus nitrate levels were significantly lower than those of vehicle-treated Spr-/- mice and were approximately the same as vehicle- and BH4-supplemented Spr+/+ mice. Nitrates 189-196 sepiapterin reductase Mus musculus 107-110 35357062-5 2022 We demonstrated distinct salt stress resistance between Ler and Col-0 depending on the differences in nitrate level, which was explained by different regulation of the NIA2 gene expression in these two ecotypes. Nitrates 102-109 nitrate reductase 2 Arabidopsis thaliana 168-172 35417808-7 2022 Furthermore, the NO3-/Cl- versus Cl- diagram and principal component analysis (PCA) indicated nitrate pollution in groundwater that is subjected to anthropogenic activities such as domestic sewage, agricultural and industrial practices, which lead to degradation of groundwater quality in the area. Nitrates 94-101 NBL1, DAN family BMP antagonist Homo sapiens 17-20 35392923-8 2022 The functionality of the NOS2-2 protein was analyzed by transient transfection of expression clones in human DLD1 cells and nitrate measurement in the supernatant of these cells. Nitrates 124-131 nitric oxide synthase 2 Homo sapiens 25-31 35299236-1 2022 Electrocatalytic nitrate (NO3-) reduction not only generates high-value ammonia (NH3) but holds significant potential in the control of NO3- contaminants in natural environments. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 26-29 35299236-1 2022 Electrocatalytic nitrate (NO3-) reduction not only generates high-value ammonia (NH3) but holds significant potential in the control of NO3- contaminants in natural environments. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 136-139 35459501-7 2022 The formation of nitrate at night mainly originated from N2O5 uptake, and the maximum production rate of NO3- reached 6.5 ppbv/hr. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 105-108 35459501-9 2022 The predominant roles of NO3 and N2O5 in nitrate formation and NOx removal in the YRD region was highlighted in this study. Nitrates 41-48 NBL1, DAN family BMP antagonist Homo sapiens 25-28 35229477-1 2022 Ammonium (NH4 + ) and nitrate (NO3 - ) are major inorganic nitrogen (N) source for plants. Nitrates 22-29 NBL1, DAN family BMP antagonist Homo sapiens 31-34 35229477-3 2022 NO3 - usually causes no toxicity and can mitigate ammonium toxicity even at low concentrations, referring to as nitrate-dependent alleviation of ammonium toxicity. Nitrates 112-119 NBL1, DAN family BMP antagonist Homo sapiens 0-3 35229477-11 2022 Our study thus revealed NRT1.1 and SLAH3 form a functional unit to regulate nitrate-dependent alleviation of ammonium toxicity through regulating NO3 - transport and balancing rhizosphere acidification. Nitrates 76-83 NBL1, DAN family BMP antagonist Homo sapiens 146-149 35365707-1 2022 Changes in the aerosol composition of sulfate (SO42-) and nitrate (NO3-) from 2012 to 2019 have been captured as a paradigm shift in the region downwind of China. Nitrates 58-65 NBL1, DAN family BMP antagonist Homo sapiens 67-70 35240317-1 2022 Exercise tolerance appears to benefit most from dietary nitrate (NO3-) supplementation when muscle oxygen (O2) availability is low. Nitrates 56-63 NBL1, DAN family BMP antagonist Homo sapiens 65-68 35240317-6 2022 Nitrate supplementation increased plasma NO3- (16.2-fold) and NO2- (4.2-fold) and time to volitional fatigue (61.8 +- 56.5 s longer duration vs. placebo visit; p = 0.03). Nitrates 0-7 NBL1, DAN family BMP antagonist Homo sapiens 41-44 35217293-0 2022 Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1alpha pathway. Nitrates 10-17 thymoma viral proto-oncogene 1 Mus musculus 147-150 35217293-0 2022 Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1alpha pathway. Nitrates 10-17 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 151-160 35217293-11 2022 Mechanistically, boosting the nitrate-nitrite-NO pathway promoted AMP-activated protein kinase (AMPK) phosphorylation, improved AKT-mediated peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) activity and restored mitochondrial function. Nitrates 30-37 thymoma viral proto-oncogene 1 Mus musculus 128-131 35217293-11 2022 Mechanistically, boosting the nitrate-nitrite-NO pathway promoted AMP-activated protein kinase (AMPK) phosphorylation, improved AKT-mediated peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) activity and restored mitochondrial function. Nitrates 30-37 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 141-209 35217293-11 2022 Mechanistically, boosting the nitrate-nitrite-NO pathway promoted AMP-activated protein kinase (AMPK) phosphorylation, improved AKT-mediated peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) activity and restored mitochondrial function. Nitrates 30-37 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 211-220 35038503-3 2022 A higher PM1 mass concentration (63.0 mug m-3) was observed in an industrially influenced district (XG) with major contributions (70.4%) from three secondary inorganic species (sulfate, nitrate, and ammonium) and two oxygenated organic aerosol (OOA) components with different oxygenation levels. Nitrates 186-193 transmembrane protein 11 Homo sapiens 9-12 35038503-6 2022 The chemical formation mechanisms of secondary PM1 species in the two different districts during the daytime and nighttime are further examined, which indicated the important photochemical formations of nitrate in CG but sulfate in XG during the daytime, whereas favorable aqueous-phase formations of nitrate and LO-OOA in both districts during the nighttime. Nitrates 203-210 transmembrane protein 11 Homo sapiens 47-50 35038503-6 2022 The chemical formation mechanisms of secondary PM1 species in the two different districts during the daytime and nighttime are further examined, which indicated the important photochemical formations of nitrate in CG but sulfate in XG during the daytime, whereas favorable aqueous-phase formations of nitrate and LO-OOA in both districts during the nighttime. Nitrates 301-308 transmembrane protein 11 Homo sapiens 47-50 35041959-5 2022 Ship emitted single particles contain organic carbon (OC), elemental carbon (EC), metals, sulfate and nitrate. Nitrates 102-109 inositol polyphosphate-5-phosphatase D Homo sapiens 0-4 35254167-6 2022 The microbial consortia in B. glabrata helped in the digestion of complex polysaccharide such as starch, hemicellulose, and chitin for energy supply, and protected the snail from food poisoning and nitrate toxicity. Nitrates 198-205 snail family transcriptional repressor 1 Homo sapiens 168-173 35146519-2 2022 In Lotus japonicus, two NODULE INCEPTION (NIN)-LIKE PROTEIN (NLP) transcription factors, LjNLP4 and LjNLP1, play pivotal roles in the negative regulation of nodulation by controlling the expression of symbiotic genes in high nitrate conditions. Nitrates 225-232 NLP1 Lotus japonicus 100-106 35146519-6 2022 LjNLP1 is necessary and sufficient to induce LjNRT2.1 expression, thereby regulating nitrate uptake/transport. Nitrates 85-92 NLP1 Lotus japonicus 0-6 35146519-8 2022 We further show that LjNIN, a positive regulator of nodulation, counteracts the LjNLP1-dependent induction of LjNRT2.1 expression, which is linked to a reduction in nitrate uptake. Nitrates 165-172 nin Lotus japonicus 21-26 35146519-8 2022 We further show that LjNIN, a positive regulator of nodulation, counteracts the LjNLP1-dependent induction of LjNRT2.1 expression, which is linked to a reduction in nitrate uptake. Nitrates 165-172 NLP1 Lotus japonicus 80-86 35394760-2 2022 In this work, FeOOH nanorod with intrinsic oxygen vacancy supported on carbon paper (FeOOH/CP) is proposed as a high-performance electrocatalyst for converting nitrate to ammonia at room temperature. Nitrates 160-167 ceruloplasmin Homo sapiens 91-93 35436155-2 2022 OBJECTIVE: To measure temporal trends in the coprescription of nitrates and PDE5 inhibitors and to measure the association between cardiovascular outcomes and the coprescription of nitrates with PDE5 inhibitors. Nitrates 181-189 phosphodiesterase 5A Homo sapiens 195-199 35436155-9 2022 During this period, the prescription rate for PDE5 inhibitors in patients with IHD who were taking nitrates increased from an average of 0.9 prescriptions (95% CI, 0.5 to 1.2 prescriptions) per 100 persons per year in 2000 to 19.5 prescriptions (CI, 18.0 to 21.1 prescriptions) in 2018. Nitrates 99-107 phosphodiesterase 5A Homo sapiens 46-50 35436155-12 2022 CONCLUSION: From 2000 to 2018, the use of PDE5 inhibitors increased 20-fold among Danish patients with IHD who were taking nitrates. Nitrates 123-131 phosphodiesterase 5A Homo sapiens 42-46 35357149-0 2022 Arc-Induced Nitrate Reagent Ion for Analysis of Trace Explosives on Surfaces Using Atmospheric Pressure Arc Desorption/Ionization Mass Spectrometry. Nitrates 12-19 activity regulated cytoskeleton associated protein Homo sapiens 0-3 35357149-0 2022 Arc-Induced Nitrate Reagent Ion for Analysis of Trace Explosives on Surfaces Using Atmospheric Pressure Arc Desorption/Ionization Mass Spectrometry. Nitrates 12-19 activity regulated cytoskeleton associated protein Homo sapiens 104-107 35357149-2 2022 In APADI, neutral explosives readily bind to the gas-phase nitrate ion, NO3-, induced by arc discharge to form anionic adducts (M+NO3)-. Nitrates 59-66 activity regulated cytoskeleton associated protein Homo sapiens 89-92 35348891-1 2022 MAIN CONCLUSION: The local and long-distance signaling pathways mediated by the leucine-rich repeat receptor kinase HAR1 suppress root branching and promote primary root length in response to nitrate supply. Nitrates 192-199 CM0216.560.nc Lotus japonicus 116-120 35355184-0 2022 Identification of sources and transformations of nitrate in Cr(VI)-impacted alluvial aquifers by a hydrogeochemical and delta15N-NO3- and delta18O-NO3 - isotopes approach. Nitrates 49-56 NBL1, DAN family BMP antagonist Homo sapiens 129-132 35355184-0 2022 Identification of sources and transformations of nitrate in Cr(VI)-impacted alluvial aquifers by a hydrogeochemical and delta15N-NO3- and delta18O-NO3 - isotopes approach. Nitrates 49-56 NBL1, DAN family BMP antagonist Homo sapiens 147-150 35352014-1 2022 BACKGROUND/OBJECTIVES: To compare the effects of supplemental inorganic nitrate (NO3) on microvascular endothelial function and blood pressure in younger vs. older participants. Nitrates 72-79 NBL1, DAN family BMP antagonist Homo sapiens 81-84 35348891-7 2022 We show that the har1 mutant exhibits high nitrate sensitivity during root development. Nitrates 43-50 CM0216.560.nc Lotus japonicus 17-21 35348891-8 2022 The uninfected har1 mutant significantly increased lateral root number and reduced primary root length in the presence of 3 mM nitrate, compared with the wild-type and tml mutant. Nitrates 127-134 CM0216.560.nc Lotus japonicus 15-19 35348891-9 2022 Grafting experiments indicated that local and long-distance signaling pathways via root- and shoot-acting HAR1 additively regulated root morphology under the moderate nitrate concentrations. Nitrates 167-174 CM0216.560.nc Lotus japonicus 106-110 35348891-10 2022 These findings allow us to propose that HAR1-mediated signaling pathways control the root system architecture by suppressing lateral root branching and promoting primary root elongation in response to nitrate availability. Nitrates 201-208 CM0216.560.nc Lotus japonicus 40-44 35364374-5 2022 However, the application of Se at 4 and 16 mumol L-1, prompted a relief of this stress, reducing both lipid peroxidation and the sugar content, and increasing the nitrate concentration. Nitrates 163-170 squalene epoxidase Homo sapiens 28-30 35364374-6 2022 In addition, in the case of the highest concentration of Se (16 mumol L-1), the values of nitrate were comparable those control plants. Nitrates 90-97 squalene epoxidase Homo sapiens 57-59 35360239-2 2022 This study investigates if performance at simulated altitude is improved to a larger extent when high-intensity interval training is performed in normobaric hypoxia and if this is potentiated when combined with chronic dietary nitrate (NO3 -) supplementation. Nitrates 227-234 NBL1, DAN family BMP antagonist Homo sapiens 236-239 34978758-1 2022 The electrocatalytic nitrate-to-ammonia reduction reaction route (NARR) is one of the emerging routes toward the green ammonia synthesis, and its conversion efficiency is controlled mainly by the hydrogenation selectivity. Nitrates 21-28 ras-related protein Rab-34 Homo sapiens 66-70 35293417-3 2022 Inorganic nitrate is a ubiquitous component of atmospheric aqueous phases such as cloudwater, fog, and aqueous aerosols. Nitrates 10-17 zinc finger protein, FOG family member 1 Homo sapiens 94-97 35424754-4 2022 To have a better understanding of the structure-property relationships of furazan-bicyclic scaffolds and nitrate groups, their thermal behaviors, detonation performances and the sensitivities were investigated via differential scanning calorimetry (DSC), ESP analysis, Hirshfeld surfaces calculation, EXPLO5 program and BAM standard techniques. Nitrates 105-112 protein tyrosine phosphatase receptor type V, pseudogene Homo sapiens 255-258 34998066-7 2022 Within 2 h of electrolysis, Cu/MWVNT/FTO exhibits more than 65% removal of nitrate at -1.80 V (vs. SCE). Nitrates 75-82 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 37-40 35263337-8 2022 Using RNA sequencing analysis and in vitro biochemical experiment, we found NAC056 regulated the expression of genes required for NO3- assimilation, directly targeting the key nitrate assimilation gene NIA1. Nitrates 176-183 nitrate reductase 1 Arabidopsis thaliana 202-206 35263337-9 2022 In addition, mutation of NIA1 suppresses LR development and nitrate deficiency tolerance in the 35S::NAC056 transgenic plants. Nitrates 60-67 nitrate reductase 1 Arabidopsis thaliana 25-29 35235063-2 2022 The sources and transport of nitrate (NO3-) in urban stormwater runoff were investigated by analysing different forms of N, water isotopes (deltaD-H2O and delta18O-H2O), and NO3- isotopes (delta15N-NO3- and delta18O-NO3-) in urban stormwater runoff in a residential area in Hangzhou, China. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 38-41 35235063-2 2022 The sources and transport of nitrate (NO3-) in urban stormwater runoff were investigated by analysing different forms of N, water isotopes (deltaD-H2O and delta18O-H2O), and NO3- isotopes (delta15N-NO3- and delta18O-NO3-) in urban stormwater runoff in a residential area in Hangzhou, China. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 198-201 35235063-2 2022 The sources and transport of nitrate (NO3-) in urban stormwater runoff were investigated by analysing different forms of N, water isotopes (deltaD-H2O and delta18O-H2O), and NO3- isotopes (delta15N-NO3- and delta18O-NO3-) in urban stormwater runoff in a residential area in Hangzhou, China. Nitrates 29-36 NBL1, DAN family BMP antagonist Homo sapiens 216-219 35150744-5 2022 In each of these two cases, the maximum amount of nitrite or nitrate formed was at best stoichiometric with the concentration of Mka HLP. Nitrates 61-68 HLP Homo sapiens 133-136 35241877-6 2022 Nitrate losses at landscape scale increased during the 2019-2020 extreme wet-weather period to 2.04-4.54 kg ha-1. Nitrates 0-7 Rho GTPase activating protein 45 Homo sapiens 108-112 34998066-13 2022 Compared to earlier systems, the Cu/MWCNT/FTO is environmentally stable, safe, non-costly with high nitrate removal efficiency and selectivity. Nitrates 100-107 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 42-45 34787344-1 2022 RATIONALE: Analyses of the isotope ratios of nitrogen (15 N/14 N) and oxygen (18 O/16 O) in nitrate (NO3 - ) with the denitrifier method require relatively high sample volumes at low concentrations (<= 1 muM) to afford sufficient analyte for mass spectrometry, resulting in isotopic offsets compared to more concentrated samples of the same isotopic composition. Nitrates 92-99 NBL1, DAN family BMP antagonist Homo sapiens 101-104 35007932-0 2022 Creatine nitrate supplementation strengthens energy status and delays glycolysis of broiler muscle via inhibition of LKB1/AMPK pathway. Nitrates 9-16 serine/threonine kinase 11 Homo sapiens 117-121 35007932-0 2022 Creatine nitrate supplementation strengthens energy status and delays glycolysis of broiler muscle via inhibition of LKB1/AMPK pathway. Nitrates 9-16 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 122-126 35391922-2 2022 At least two major pathways produce NO: (1) the L-arginine-NO-oxidative pathway in which NO synthase (NOS) enzymes convert L-arginine to NO; (2) the nitrate-nitrite-NO reductive pathway in which NO is produced from the serial reduction of nitrate and nitrite. Nitrates 239-246 nitric oxide synthase 2 Homo sapiens 89-100 35047570-6 2021 Correlation analysis showed MEG3 expression highly correlated with ET1 and Nitrate concentration. Nitrates 75-82 maternally expressed 3 Homo sapiens 28-32 35163124-1 2022 The two homologous genes, NIA1 and NIA2, encode nitrate reductases in Arabidopsis, which govern the reduction of nitrate to nitrite. Nitrates 113-120 nitrate reductase 1 Arabidopsis thaliana 26-30 35163124-1 2022 The two homologous genes, NIA1 and NIA2, encode nitrate reductases in Arabidopsis, which govern the reduction of nitrate to nitrite. Nitrates 113-120 nitrate reductase 2 Arabidopsis thaliana 35-39 35045112-11 2022 Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition. Nitrates 83-90 glucan endo-1,3-beta-glucosidase, basic isoform Malus domestica 8-13 35045112-11 2022 Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition. Nitrates 83-90 glucan endo-1,3-beta-glucosidase, basic isoform Malus domestica 18-23 35046428-10 2022 These findings offer new perspectives on the mechanisms by which the chrysanthemum CBL interacting protein kinase CmCIPK23 influences nitrate signaling. Nitrates 134-141 cystathionine beta-lyase Arabidopsis thaliana 83-86 35052670-4 2022 The organic nitrates studied showed different vasodilation and tolerance profiles, probably due to the ability or inability of the compounds to interact with the aldehyde dehydrogenase-2 enzyme (ALDH-2) involved in bioactivation. Nitrates 12-20 aldehyde dehydrogenase 2 family member Homo sapiens 162-186 35052670-4 2022 The organic nitrates studied showed different vasodilation and tolerance profiles, probably due to the ability or inability of the compounds to interact with the aldehyde dehydrogenase-2 enzyme (ALDH-2) involved in bioactivation. Nitrates 12-20 aldehyde dehydrogenase 2 family member Homo sapiens 195-201 35052670-6 2022 The results of this study could be further evidence of the involvement of ALDH-2 in the development of nitrate tolerance. Nitrates 103-110 aldehyde dehydrogenase 2 family member Homo sapiens 74-80 35052670-7 2022 Moreover, the behavior of organic nitrates with antioxidant properties supports the hypothesis of the involvement of ROS in inactivating ALDH-2. Nitrates 34-42 aldehyde dehydrogenase 2 family member Homo sapiens 137-143 35095967-16 2021 Overall, these results demonstrated that increasing the NH4 +/NO3 - ratio at the seedling stage induced the accumulation of reactive oxygen species, which in turn enhanced root glutathione metabolism and lignification, thereby resulting in increased root oxidative tolerance at the cost of reducing nitrate transport and utilization, which reduced leaf photosynthetic capacity and, ultimately, plant biomass accumulation. Nitrates 299-306 NBL1, DAN family BMP antagonist Homo sapiens 62-65 35095982-4 2021 Ion-selective electrodes (ISEs) support the possibility of NO 3 - -N measurement by measuring the nitrate ( NO 3 - ) ions in soil quickly and accurately due to the high water solubility and mobility of NO 3 - ions. Nitrates 99-106 NBL1, DAN family BMP antagonist Homo sapiens 59-63 35095982-4 2021 Ion-selective electrodes (ISEs) support the possibility of NO 3 - -N measurement by measuring the nitrate ( NO 3 - ) ions in soil quickly and accurately due to the high water solubility and mobility of NO 3 - ions. Nitrates 99-106 NBL1, DAN family BMP antagonist Homo sapiens 109-113 35095982-4 2021 Ion-selective electrodes (ISEs) support the possibility of NO 3 - -N measurement by measuring the nitrate ( NO 3 - ) ions in soil quickly and accurately due to the high water solubility and mobility of NO 3 - ions. Nitrates 99-106 NBL1, DAN family BMP antagonist Homo sapiens 204-208 35046980-5 2021 The SSP, CEP1 (C-TERMINALLY ENCODED PEPTIDE) enhanced nitrate uptake rate per unit root length in Medicago truncatula plants deprived of N in the high-affinity transport range. Nitrates 54-61 Cysteine proteinases superfamily protein Arabidopsis thaliana 9-13 35046980-6 2021 Single structural variants of M. truncatula and Arabidopsis thaliana specific CEP1 peptides, MtCEP1D1:hyp4,11 and AtCEP1:hyp4,11, enhanced uptake not only of nitrate, but also phosphate and sulfate in both model plant species. Nitrates 158-165 Cysteine proteinases superfamily protein Arabidopsis thaliana 78-82 35046980-6 2021 Single structural variants of M. truncatula and Arabidopsis thaliana specific CEP1 peptides, MtCEP1D1:hyp4,11 and AtCEP1:hyp4,11, enhanced uptake not only of nitrate, but also phosphate and sulfate in both model plant species. Nitrates 158-165 Cysteine proteinases superfamily protein Arabidopsis thaliana 114-120 35101982-2 2022 The electrochemical nitrate reduction reaction (NO3 -RR) is a promising approach for nitrate removal and NH3 production at ambient conditions, but efficient electrocatalysts are lacking. Nitrates 20-27 NBL1, DAN family BMP antagonist Homo sapiens 48-51 35101982-2 2022 The electrochemical nitrate reduction reaction (NO3 -RR) is a promising approach for nitrate removal and NH3 production at ambient conditions, but efficient electrocatalysts are lacking. Nitrates 85-92 NBL1, DAN family BMP antagonist Homo sapiens 48-51 35161943-2 2022 The first nitrate transporter activity biosensor NiTrac1 converted the dual-affinity nitrate transceptor NPF6.3 into fluorescence activity sensors. Nitrates 10-17 nitrate transporter 1.1 Arabidopsis thaliana 105-111 35161943-2 2022 The first nitrate transporter activity biosensor NiTrac1 converted the dual-affinity nitrate transceptor NPF6.3 into fluorescence activity sensors. Nitrates 85-92 nitrate transporter 1.1 Arabidopsis thaliana 105-111 35128037-8 2022 The wastewater analyses confirm the occurrence of nitrate (NO3 -), nitrite (NO2 -), and ammonia (NH4 +), which provide an appropriate condition for NO2 release. Nitrates 50-57 NBL1, DAN family BMP antagonist Homo sapiens 59-62 35067307-0 2022 Overexpression of tomato thioredoxin h (SlTrxh) enhances excess nitrate stress tolerance in transgenic tobacco interacting with SlPrx protein. Nitrates 64-71 thioredoxin-like protein CITRX, chloroplastic Solanum lycopersicum 25-36 34545936-3 2022 In addition, genetic and molecular analysis showed that BRM interacts with GNC (GATA, NITRATE-INDUCIBLE, CARBONMETABOLISM INVOLVED), a GATA transcription factor that represses flowering by directly repressing SOC1 expression. Nitrates 86-93 transcription regulatory protein SNF2 Arabidopsis thaliana 56-59 34545936-3 2022 In addition, genetic and molecular analysis showed that BRM interacts with GNC (GATA, NITRATE-INDUCIBLE, CARBONMETABOLISM INVOLVED), a GATA transcription factor that represses flowering by directly repressing SOC1 expression. Nitrates 86-93 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 75-78 34545936-3 2022 In addition, genetic and molecular analysis showed that BRM interacts with GNC (GATA, NITRATE-INDUCIBLE, CARBONMETABOLISM INVOLVED), a GATA transcription factor that represses flowering by directly repressing SOC1 expression. Nitrates 86-93 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 105-130 34545936-3 2022 In addition, genetic and molecular analysis showed that BRM interacts with GNC (GATA, NITRATE-INDUCIBLE, CARBONMETABOLISM INVOLVED), a GATA transcription factor that represses flowering by directly repressing SOC1 expression. Nitrates 86-93 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 135-139 35046022-0 2022 Spatiotemporal analysis identifies ABF2 and ABF3 as key hubs of endodermal response to nitrate. Nitrates 87-94 abscisic acid responsive elements-binding factor 2 Arabidopsis thaliana 35-39 35046022-0 2022 Spatiotemporal analysis identifies ABF2 and ABF3 as key hubs of endodermal response to nitrate. Nitrates 87-94 abscisic acid responsive elements-binding factor 3 Arabidopsis thaliana 44-48 35046022-8 2022 Validated targets of ABF2 and ABF3 account for more than 50% of the nitrate-responsive transcriptome in the endodermis. Nitrates 68-75 abscisic acid responsive elements-binding factor 2 Arabidopsis thaliana 21-25 35046022-8 2022 Validated targets of ABF2 and ABF3 account for more than 50% of the nitrate-responsive transcriptome in the endodermis. Nitrates 68-75 abscisic acid responsive elements-binding factor 3 Arabidopsis thaliana 30-34 35046022-9 2022 Moreover, ABF2 and ABF3 are involved in nitrate-induced lateral root growth. Nitrates 40-47 abscisic acid responsive elements-binding factor 2 Arabidopsis thaliana 10-14 35046022-9 2022 Moreover, ABF2 and ABF3 are involved in nitrate-induced lateral root growth. Nitrates 40-47 abscisic acid responsive elements-binding factor 3 Arabidopsis thaliana 19-23 35140727-4 2021 Our characterization of NODULE INCEPTION (NIN)-like PROTEIN 7 (NLP7), a transcription factor regulating the primary response to nitrate, revealed an intersection of salt stress and nitrate metabolism. Nitrates 128-135 NIN like protein 7 Arabidopsis thaliana 24-61 35140727-4 2021 Our characterization of NODULE INCEPTION (NIN)-like PROTEIN 7 (NLP7), a transcription factor regulating the primary response to nitrate, revealed an intersection of salt stress and nitrate metabolism. Nitrates 128-135 NIN like protein 7 Arabidopsis thaliana 63-67 35140727-4 2021 Our characterization of NODULE INCEPTION (NIN)-like PROTEIN 7 (NLP7), a transcription factor regulating the primary response to nitrate, revealed an intersection of salt stress and nitrate metabolism. Nitrates 181-188 NIN like protein 7 Arabidopsis thaliana 24-61 35140727-4 2021 Our characterization of NODULE INCEPTION (NIN)-like PROTEIN 7 (NLP7), a transcription factor regulating the primary response to nitrate, revealed an intersection of salt stress and nitrate metabolism. Nitrates 181-188 NIN like protein 7 Arabidopsis thaliana 63-67 35140727-8 2021 Since nlp7 also expressed less nitrate reductase (NR) activity, nitrate accumulated to abnormally high levels with or without salinity. Nitrates 64-71 NIN like protein 7 Arabidopsis thaliana 6-10 35140727-8 2021 Since nlp7 also expressed less nitrate reductase (NR) activity, nitrate accumulated to abnormally high levels with or without salinity. Nitrates 64-71 nitrate reductase 1 Arabidopsis thaliana 31-48 35140727-8 2021 Since nlp7 also expressed less nitrate reductase (NR) activity, nitrate accumulated to abnormally high levels with or without salinity. Nitrates 64-71 nitrate reductase 1 Arabidopsis thaliana 50-52 35140727-9 2021 We attributed the enhanced salt tolerance of nlp7 to the balanced accumulation of nitrate anions and sodium cations. Nitrates 82-89 NIN like protein 7 Arabidopsis thaliana 45-49 2544557-3 1989 We have previously identified a locus called frdR which pleiotropically affects nitrate repression of fumarate reductase, trimethylamine N-oxide reductase, and alcohol dehydrogenase gene expression and nitrate induction of nitrate reductase expression (L. V. Kalman and R. P. Gunsalus, J. Bacteriol. Nitrates 80-87 Alcohol dehydrogenase Escherichia coli 160-181 2557415-9 1989 Thus, it is apparently the nitrate moiety of the chemical structure by which nicorandil actively and strongly reduces [Ca++]i in vascular smooth muscle cells. Nitrates 27-34 carbonic anhydrase 1 Rattus norvegicus 119-125 16667152-6 1989 Incorporation of [(35)S]methionine during nitrate treatment revealed that total soluble protein and nitrate reductase protein synthesis were both depressed by the O(2) environment relative to air, but both recovered when leaves were shifted from O(2) to air. Nitrates 42-49 nitrate reductase [NADH] 1 Zea mays 100-117 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 0-7 alternative oxidase 1A Arabidopsis thaliana 44-49 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 0-7 plant uncoupling mitochondrial protein 1 Arabidopsis thaliana 50-54 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 120-127 alternative oxidase 1A Arabidopsis thaliana 44-49 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 120-127 plant uncoupling mitochondrial protein 1 Arabidopsis thaliana 50-54 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 140-147 alternative oxidase 1A Arabidopsis thaliana 44-49 34974624-7 2022 Nitrate acquisition rate was accelerated in aox1a/ucp1, but its transport activity was decreased, which resulted in low nitrate content and nitrate reductase activity under low N condition. Nitrates 140-147 plant uncoupling mitochondrial protein 1 Arabidopsis thaliana 50-54 2517590-4 1989 In addition, while the expression of c-myc, following partial hepatectomy returned to basal level by 4 h, the induced expression of c-myc persisted for up to 40 h during the lead nitrate-induced liver cell proliferation. Nitrates 179-186 MYC proto-oncogene, bHLH transcription factor Rattus norvegicus 37-42 2517590-4 1989 In addition, while the expression of c-myc, following partial hepatectomy returned to basal level by 4 h, the induced expression of c-myc persisted for up to 40 h during the lead nitrate-induced liver cell proliferation. Nitrates 179-186 MYC proto-oncogene, bHLH transcription factor Rattus norvegicus 132-137 2790879-12 1989 With regard to the very satisfactory experience with the administration of nitrates in this indication their combined administration with vasopressin or its derivatives is considered. Nitrates 75-83 arginine vasopressin Homo sapiens 138-149 16666874-0 1989 Transient Accumulation of Nitrite Reductase mRNA in Maize following the Addition of Nitrate. Nitrates 84-91 ferredoxin--nitrite reductase, chloroplastic Zea mays 26-43 16666874-1 1989 Expression of the gene coding for nitrite reductase (NiR) is induced upon the addition of nitrate. Nitrates 90-97 ferredoxin--nitrite reductase, chloroplastic Zea mays 34-51 16666905-3 1989 Both NR and NiR mRNA were transiently induced with levels decreasing after the 2 hours despite the continued presence of nitrate in the medium. Nitrates 121-128 nitrate reductase [NADH] 1 Zea mays 5-7 16666874-1 1989 Expression of the gene coding for nitrite reductase (NiR) is induced upon the addition of nitrate. Nitrates 90-97 ferredoxin--nitrite reductase, chloroplastic Zea mays 53-56 16666905-3 1989 Both NR and NiR mRNA were transiently induced with levels decreasing after the 2 hours despite the continued presence of nitrate in the medium. Nitrates 121-128 ferredoxin--nitrite reductase, chloroplastic Zea mays 12-15 16666874-3 1989 There is a rapid induction of NiR mRNA upon addition of nitrate, increasing first in the roots and then in the leaves. Nitrates 56-63 ferredoxin--nitrite reductase, chloroplastic Zea mays 30-33 2577296-2 1989 The recently elucidated mechanism of action of nitrates, acting on a common pathway with the endothelium-derived relaxation factor (EDRF), suggests an important role for guanylate cyclase and cyclic GMP in maintaining coronary artery patency in patients with coronary atheroma. Nitrates 47-55 alpha hemoglobin stabilizing protein Homo sapiens 93-130 2577296-2 1989 The recently elucidated mechanism of action of nitrates, acting on a common pathway with the endothelium-derived relaxation factor (EDRF), suggests an important role for guanylate cyclase and cyclic GMP in maintaining coronary artery patency in patients with coronary atheroma. Nitrates 47-55 alpha hemoglobin stabilizing protein Homo sapiens 132-136 2577296-2 1989 The recently elucidated mechanism of action of nitrates, acting on a common pathway with the endothelium-derived relaxation factor (EDRF), suggests an important role for guanylate cyclase and cyclic GMP in maintaining coronary artery patency in patients with coronary atheroma. Nitrates 47-55 5'-nucleotidase, cytosolic II Homo sapiens 199-202 2501096-5 1989 More recently, a potential molecular explanation for nitrate tolerance has been proposed: sulfhydryl group depletion in smooth muscle cells resulting in reduced formation of S-nitrosothiols on nitrate exposure with resultant reduced activation of cyclic GMP. Nitrates 53-60 5'-nucleotidase, cytosolic II Homo sapiens 254-257 2548453-3 1989 The study showed that the nitrate content in berseem grown near the factory had higher NO3 values exceeding 2% NO3 in DM in some cases. Nitrates 26-33 NBL1, DAN family BMP antagonist Homo sapiens 87-90 2548453-3 1989 The study showed that the nitrate content in berseem grown near the factory had higher NO3 values exceeding 2% NO3 in DM in some cases. Nitrates 26-33 NBL1, DAN family BMP antagonist Homo sapiens 111-114 2658373-1 1989 Metabolism of organic nitrates results in the formation of inorganic nitrites that can oxidize hemoglobin to methemoglobin. Nitrates 22-30 hemoglobin subunit gamma 2 Homo sapiens 109-122 2658373-3 1989 Based on the results of these trials, organic nitrate use does appear to increase methemoglobin content but not to a clinically significant extent. Nitrates 46-53 hemoglobin subunit gamma 2 Homo sapiens 82-95 16347879-3 1989 Nitrate affinity (K(m)) for mixed populations of denitrifying bacteria in unfertilized agricultural soils and pond sediments ranged from 1.8 to 13.7 muM. Nitrates 0-7 latexin Homo sapiens 149-152 2722365-1 1989 Increasing levels of nitrate (NO3-) in drinking water in Denmark is of concern due to the possibility of an associated increase in long-term exposure to endogeneously formed N-nitroso compounds. Nitrates 21-28 NBL1, DAN family BMP antagonist Homo sapiens 30-33 2722365-3 1989 People drinking nitrate-free water have an intake of 37 mg NO3- per day. Nitrates 16-23 NBL1, DAN family BMP antagonist Homo sapiens 59-62 2784476-1 1989 L-arginine-dependent synthesis of nitrite (NO2-) and nitrate (NO3-) by macrophages correlates with and is required for their execution of nonspecific cytotoxicity toward some tumor cells and microbes. Nitrates 53-60 NBL1, DAN family BMP antagonist Mus musculus 62-65 2733245-3 1989 Plasma SOD activities were measured by the nitrate method. Nitrates 43-50 superoxide dismutase 1 Homo sapiens 7-10 16666874-9 1989 The NiR protein level, on the other hand, increases gradually somewhat after the increase in mRNA and remains at high levels at least for 24 hours after the addition of nitrate. Nitrates 169-176 ferredoxin--nitrite reductase, chloroplastic Zea mays 4-7 16666879-5 1989 When nitrate was supplied to N-starved, etiolated corn plants, nitrate reductase, and glyceraldehyde-3-phosphate dehydrogenase mRNA levels in leaves increased in parallel. Nitrates 5-12 nitrate reductase [NADH] 1 Zea mays 63-80 16666879-5 1989 When nitrate was supplied to N-starved, etiolated corn plants, nitrate reductase, and glyceraldehyde-3-phosphate dehydrogenase mRNA levels in leaves increased in parallel. Nitrates 5-12 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Zea mays 86-126 16666879-6 1989 When green leaves were treated with nitrate, only nitrate reductase mRNA levels were increased. Nitrates 36-43 nitrate reductase [NADH] 1 Zea mays 50-67 16666879-7 1989 Nitrate is a specific inducer of nitrate reductase in green leaves, but appears to have a more general effect in etiolated leaves. Nitrates 0-7 nitrate reductase [NADH] 1 Zea mays 33-50 16666879-8 1989 In the dark, nitrate induced nitrate reductase expression in both etiolated and green leaves, indicating light and functional chloroplast were not required for enzyme expression. Nitrates 13-20 nitrate reductase [NADH] 1 Zea mays 29-46 16666905-0 1989 Nitrate effects on nitrate reductase activity and nitrite reductase mRNA levels in maize suspension cultures. Nitrates 0-7 nitrate reductase [NADH] 1 Zea mays 19-36 16666905-0 1989 Nitrate effects on nitrate reductase activity and nitrite reductase mRNA levels in maize suspension cultures. Nitrates 0-7 ferredoxin--nitrite reductase, chloroplastic Zea mays 50-67 2468964-2 1989 The present study was performed to elucidate if large oral doses of N-acetylcysteine (NAC, 2,400 mg X 2), a donor of sulfhydryl groups, given together with a single oral dose of the long-acting nitrate, isosorbide-5-mononitrate (5-ISMN, 60 mg), would modify the nitrate effect evaluated by exercise testing before and after additional sublingual doses of nitroglycerin (NTG). Nitrates 194-201 NACC family member 2 Homo sapiens 68-103 2468964-2 1989 The present study was performed to elucidate if large oral doses of N-acetylcysteine (NAC, 2,400 mg X 2), a donor of sulfhydryl groups, given together with a single oral dose of the long-acting nitrate, isosorbide-5-mononitrate (5-ISMN, 60 mg), would modify the nitrate effect evaluated by exercise testing before and after additional sublingual doses of nitroglycerin (NTG). Nitrates 220-227 NACC family member 2 Homo sapiens 68-103 2511690-7 1989 The real clinical importance of nitrates became, however, evident only in the last decade with the discovery of EDRF, the so-called endothelial-derived relaxing factor, an endogenous compound of endothelial origin at least partly consisting of nitrous oxide and therefore, like nitrates, it exerts its effect through the stimulation of cGMP. Nitrates 32-40 alpha hemoglobin stabilizing protein Homo sapiens 112-116 2568418-4 1989 Some auranofin analogues having chloride or nitrate leaving groups that inhibit DNA polymerase-alpha were found to be potent inhibitors of IL-1 induced resorption. Nitrates 44-51 DNA polymerase alpha 1, catalytic subunit Homo sapiens 80-100 2559883-3 1989 Nitrosylhemoglobin shows a characteristic electron spin resonance (ESR) signal due to an odd electron localized on the nitrogen atom of NO and reacts with oxygen to yield nitrate and methemoglobin, which is rapidly reduced by methemoglobin reductase in red cells. Nitrates 171-178 hemoglobin subunit gamma 2 Homo sapiens 226-239 2573982-4 1989 CONCLUSION: A desensitization of soluble guanylate cyclase to activation with NO can be demonstrated under non-physiological conditions (disrupted cells) in homogenates from nitrate tolerant RA. Nitrates 174-181 guanylate cyclase Bos taurus 41-58 16666376-5 1988 Nitrate stimulated a rapid induction of the NiR mRNA in both roots and leaves. Nitrates 0-7 ferredoxin--nitrite reductase, chloroplastic Zea mays 44-47 2511690-7 1989 The real clinical importance of nitrates became, however, evident only in the last decade with the discovery of EDRF, the so-called endothelial-derived relaxing factor, an endogenous compound of endothelial origin at least partly consisting of nitrous oxide and therefore, like nitrates, it exerts its effect through the stimulation of cGMP. Nitrates 278-286 alpha hemoglobin stabilizing protein Homo sapiens 112-116 2555979-3 1989 Nitrate (GTN)-induced relaxation was accompanied by a 2- to 3-fold increase of cyclic GMP content in the vessel walls. Nitrates 0-7 5'-nucleotidase, cytosolic II Homo sapiens 86-89 2573982-2 1989 Nitrate tolerance significantly attenuated NTG-induced vasodilation of precontracted (1.0 microM norepinephrine) RA, increase in cyclic GMP in RA and SMC, and activation of guanylate cyclase in homogenates as compared to controls. Nitrates 0-7 guanylate cyclase Bos taurus 173-190 16666423-0 1988 The role of nitrate and ammonium ions and light on the induction of nitrate reductase in maize leaves. Nitrates 12-19 nitrate reductase [NADH] 1 Zea mays 68-85 16666409-8 1988 Only the plastidic portion of the glutamine synthetase increased to about 80% in cells grown on ammonium (compared to about 40% in cells grown on nitrate). Nitrates 146-153 uncharacterized protein Chlamydomonas reinhardtii 34-54 3170537-4 1988 Mutant 2172 is affected in methylammonium but not in ammonium uptake capacity and shows derepressed nitrate and nitrite reductase activities in media containing nitrate plus methylammonium but not in nitrate plus ammonium media. Nitrates 161-168 uncharacterized protein Chlamydomonas reinhardtii 112-129 3170537-4 1988 Mutant 2172 is affected in methylammonium but not in ammonium uptake capacity and shows derepressed nitrate and nitrite reductase activities in media containing nitrate plus methylammonium but not in nitrate plus ammonium media. Nitrates 161-168 uncharacterized protein Chlamydomonas reinhardtii 112-129 3170537-7 1988 From genetic and kinetic evidences we conclude that in C. reinhardtii two different carriers are responsible for the transport of both ammonium and methylammonium and that methylammonium (ammonium) transport is a reversible process probably inhibited by the intracellular ammonium which, in turn, regulates nitrate and nitrite reductase levels. Nitrates 307-314 uncharacterized protein Chlamydomonas reinhardtii 319-336 3142779-2 1988 Recombinant interferon-gamma (rIFN-gamma) and recombinant tumor necrosis factor (rTNF) synergize to induce nitrite (NO2-) and nitrate (NO3-) synthesis from L-arginine as well as to cause inhibition of the iron-dependent enzyme aconitase in macrophages. Nitrates 126-133 interferon gamma Mus musculus 12-28 3142779-2 1988 Recombinant interferon-gamma (rIFN-gamma) and recombinant tumor necrosis factor (rTNF) synergize to induce nitrite (NO2-) and nitrate (NO3-) synthesis from L-arginine as well as to cause inhibition of the iron-dependent enzyme aconitase in macrophages. Nitrates 126-133 interferon gamma Rattus norvegicus 30-40 3142779-2 1988 Recombinant interferon-gamma (rIFN-gamma) and recombinant tumor necrosis factor (rTNF) synergize to induce nitrite (NO2-) and nitrate (NO3-) synthesis from L-arginine as well as to cause inhibition of the iron-dependent enzyme aconitase in macrophages. Nitrates 126-133 tumor necrosis factor Mus musculus 58-79 3142779-2 1988 Recombinant interferon-gamma (rIFN-gamma) and recombinant tumor necrosis factor (rTNF) synergize to induce nitrite (NO2-) and nitrate (NO3-) synthesis from L-arginine as well as to cause inhibition of the iron-dependent enzyme aconitase in macrophages. Nitrates 126-133 tumor necrosis factor Rattus norvegicus 81-85 3142779-2 1988 Recombinant interferon-gamma (rIFN-gamma) and recombinant tumor necrosis factor (rTNF) synergize to induce nitrite (NO2-) and nitrate (NO3-) synthesis from L-arginine as well as to cause inhibition of the iron-dependent enzyme aconitase in macrophages. Nitrates 126-133 NBL1, DAN family BMP antagonist Mus musculus 135-138 16666313-1 1988 The influence of light-dark cycles and nitrate supply on nitrate reductase (NR) mRNA levels was studied in two plant species, tobacco (Nicotiana tabacum) and tomato (Lycopersicon esculentum) using specific NR DNA probes. Nitrates 39-46 nitrate reductase [NADH] Solanum lycopersicum 57-74 16666313-1 1988 The influence of light-dark cycles and nitrate supply on nitrate reductase (NR) mRNA levels was studied in two plant species, tobacco (Nicotiana tabacum) and tomato (Lycopersicon esculentum) using specific NR DNA probes. Nitrates 39-46 nitrate reductase [NADH] Solanum lycopersicum 76-78 2851879-5 1988 The marked enrichment of H+, SO4(2-) and NO3- in precipitation compared with NH4+ could be explained by assuming either that SO2 and NO2 are oxidized in cloud droplets or that acidic sulfate and nitrate are scavenged directly in-cloud or below-cloud. Nitrates 195-202 NBL1, DAN family BMP antagonist Homo sapiens 41-44 3393528-0 1988 Sequence and nitrate regulation of the Arabidopsis thaliana mRNA encoding nitrate reductase, a metalloflavoprotein with three functional domains. Nitrates 13-20 nitrate reductase 1 Arabidopsis thaliana 74-91 16347651-0 1988 Sub-Parts-Per-Billion Nitrate Method: Use of an N(2)O-Producing Denitrifier to Convert NO(3) or NO(3) to N(2)O. Nitrates 22-29 NBL1, DAN family BMP antagonist Homo sapiens 87-92 16347651-0 1988 Sub-Parts-Per-Billion Nitrate Method: Use of an N(2)O-Producing Denitrifier to Convert NO(3) or NO(3) to N(2)O. Nitrates 22-29 NBL1, DAN family BMP antagonist Homo sapiens 96-101 16347658-2 1988 The isolate, designated GS-15, grew in defined anaerobic medium with acetate as the sole electron donor and Fe(III), Mn(IV), or nitrate as the sole electron acceptor. Nitrates 128-135 Bet1 golgi vesicular membrane trafficking protein like Homo sapiens 24-29 3154691-12 1988 Therefore nitrates may particularly be effective in vessels with deficient EDRF release. Nitrates 10-18 alpha hemoglobin stabilizing protein Homo sapiens 75-79 2439225-2 1987 Murine peritoneal macrophages, elicited in vivo with thioglycolate and stimulated in vitro with LPS and/or gamma-interferon (IFN), produce copious amounts of nitrate and nitrite. Nitrates 158-165 interferon gamma Mus musculus 107-129 2887427-15 1987 The ATPase is insensitive to azide or vanadate but is inhibited by relatively low concentrations of nitrate. Nitrates 100-107 ATZ20_RS04105 Sulfolobus acidocaldarius 4-10 3110273-0 1987 Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma. Nitrates 21-28 interferon gamma Mus musculus 95-111 3110273-5 1987 Recombinant IFN-gamma also stimulated nitrite/nitrate synthesis by C3H/He and CeH/HeJ macrophages as did LPS (C3H/He only) and hk BCG. Nitrates 46-53 interferon gamma Mus musculus 12-21 3110273-6 1987 When given concurrently with either LPS or hk BCG, IFN-gamma enhanced C3H/He and C3H/HeJ macrophage nitrite/nitrate synthesis over that produced by macrophages treated with either LPS or hk BCG alone. Nitrates 108-115 interferon gamma Mus musculus 51-60 3110273-10 1987 Taken together, these results indicate that T cell lymphokines and IFN-gamma are powerful modulators of macrophage nitrite/nitrate synthesis during BCG infection and in vitro, and nitrite/nitrate synthesis appears to be common property of both primed and fully activated macrophage populations. Nitrates 123-130 interferon gamma Mus musculus 67-76 24221417-9 1988 Nitrate reductase was induced in bacteroids of strain CB1809 when they were incubated in-vitro with nitrate or nitrite. Nitrates 100-107 inducible nitrate reductase [NADH] 1 Glycine max 0-17 3422089-2 1988 These metabolic changes occur in parallel with L-citrulline, nitrate, and nitrate synthesis from L-arginine by EMT-6 cells. Nitrates 74-81 IL2 inducible T cell kinase Mus musculus 111-114 3137069-3 1988 Evidence for nitrate induced PGI2 stimulation is presented by inhibition of its formation by indomethacin and dexamethasone, the demonstration of inhibition of thrombin induced thromboxane generation of washed platelet suspensions by nitrate stimulated vessel incubates and an enhanced accumulation of the hydrolysis product of PGI2, 6-oxo-PGF1 alpha, in incubates of teopranitol stimulated vessels. Nitrates 13-20 coagulation factor II, thrombin Bos taurus 160-168 3137069-3 1988 Evidence for nitrate induced PGI2 stimulation is presented by inhibition of its formation by indomethacin and dexamethasone, the demonstration of inhibition of thrombin induced thromboxane generation of washed platelet suspensions by nitrate stimulated vessel incubates and an enhanced accumulation of the hydrolysis product of PGI2, 6-oxo-PGF1 alpha, in incubates of teopranitol stimulated vessels. Nitrates 234-241 coagulation factor II, thrombin Bos taurus 160-168 3553637-0 1987 Landmark article Sept 8, 1945: Cyanosis in infants caused by nitrates in well-water. Nitrates 61-69 septin 8 Homo sapiens 17-23 2952501-7 1987 The ATPase activity is not inhibited by N,N"-dicyclohexylcarbodiimide, azide or vanadate, but it is by the vascular ATPase inhibitor nitrate with an [I]50 of 8 mM. Nitrates 133-140 ATZ20_RS04105 Sulfolobus acidocaldarius 4-10 2952501-7 1987 The ATPase activity is not inhibited by N,N"-dicyclohexylcarbodiimide, azide or vanadate, but it is by the vascular ATPase inhibitor nitrate with an [I]50 of 8 mM. Nitrates 133-140 ATZ20_RS04105 Sulfolobus acidocaldarius 116-122 3314296-1 1987 (A) The effects of phosphate, chloride, nitrate, pyruvate, malate, succinate and glutamate ions on the kinetics of yeast phosphoglycerate kinase (ATP: 3-phospho-D-glycerate 1-phosphotransferase, EC 2.7.2.3) were studied with MgATP2- and 3-P-glycerate as variable substrates. Nitrates 40-47 phosphoglycerate kinase Saccharomyces cerevisiae S288C 121-144 3314296-1 1987 (A) The effects of phosphate, chloride, nitrate, pyruvate, malate, succinate and glutamate ions on the kinetics of yeast phosphoglycerate kinase (ATP: 3-phospho-D-glycerate 1-phosphotransferase, EC 2.7.2.3) were studied with MgATP2- and 3-P-glycerate as variable substrates. Nitrates 40-47 F1F0 ATP synthase subunit gamma Saccharomyces cerevisiae S288C 146-152 16665499-4 1987 Addition of nitrate to inactive nitrate reductase of mutant 305 caused the in vivo reactivation of the enzyme and halted its degradation. Nitrates 12-19 uncharacterized protein Chlamydomonas reinhardtii 32-49 16347270-3 1987 Significant nitrate concentrations (1 to 27 muM) were observed in the sediment of Lake Vechten during the nonstratified period; the concentration profiles showed a successive depletion of oxygen, nitrate, and sulfate with depth. Nitrates 12-19 latexin Homo sapiens 44-47 3015963-2 1986 Besides the reduction of nitrate by NADH, nitrate reductase also catalyzes the partial activities NADH:cytochrome c reductase, NADH:ferricyanide reductase, and reduced methyl viologen:nitrate reductase. Nitrates 25-32 nitrate reductase [NADH] 1 Zea mays 42-59 16665101-1 1986 Bromphenol blue, which was reduced with dithionite, was found to support nitrate reduction catalyzed by squash NADH:nitrate reductase at a rate about 5 times greater than NADH with freshly prepared enzyme and 10 times or more with enzyme having been frozen and thawed. Nitrates 73-80 nitrate reductase [NADH] 1 Zea mays 116-133 16665101-2 1986 Kinetic analysis of bromphenol blue as a substrate for squash nitrate reductase yielded apparent K(m) values of 60 micromolar for bromphenol blue at 10 millimolar nitrate and 500 micromolar for nitrate at 0.2 millimolar bromphenol blue. Nitrates 163-170 nitrate reductase [NADH] 1 Zea mays 62-79 3798854-1 1986 The quantitative determination of nitrate-reducing microorganisms in food is important because of their role in the formation of N-nitroso compounds and methemoglobin. Nitrates 34-41 hemoglobin subunit gamma 2 Homo sapiens 153-166 3015963-2 1986 Besides the reduction of nitrate by NADH, nitrate reductase also catalyzes the partial activities NADH:cytochrome c reductase, NADH:ferricyanide reductase, and reduced methyl viologen:nitrate reductase. Nitrates 25-32 nitrate reductase [NADH] 1 Zea mays 184-201 16664862-10 1986 The results provide additional support to our claim that wild-type soybean contains three NR isozymes, namely, constitutive NADPH:NR (c(1)NR), constitutive NADH:NR (c(2)NR), and nitrate-inducible NR (iNR). Nitrates 178-185 inducible nitrate reductase [NADH] 1 Glycine max 90-92 16664678-4 1986 After 2 days of treatment with 10 millimolar nitrate, acetylene reduction by nodulated roots was inhibited by 48% but there was no effect on either acetylene reduction by isolated bacteroids or in vitro activity of nodule cytoplasmic glutamine synthetase, glutamine oxoglutarate aminotransferase, xanthine dehydrogenase, uricase, or allantoinase. Nitrates 45-52 uricase-2 isozyme 1 Glycine max 321-328 4079911-3 1985 For the organic nitrates, increases in the rate of reaction with cysteine, in general, ran parallel both with increases in pharmacological potency (flow in the Langendorff heart) and with increases in total clearance. Nitrates 16-24 RAN, member RAS oncogene family Homo sapiens 87-90 3085308-10 1986 The effects of nitrates, nitrites and mechanisms of the reconversion of methemoglobin to hemoglobin are discussed. Nitrates 15-23 HGB Sus scrofa 75-85 16664640-9 1986 Western blots of polyacrylamide gels of native and denatured crude extracts showed that NADH:NR polypeptide was absent prior to treatment with N nutrients, but appeared after nitrate was given in dark or light. Nitrates 175-182 nitrate reductase [NADH] 1 Zea mays 93-95 16664642-6 1986 Stem NO(3) (-) concentration and in vivo leaf NR activity were significantly correlated (R(2) = 0.69 with nitrate in the assay medium and 0.74 without nitrate in the medium at P = 0.001) across six combinations of reproductive and soil N-treatment. Nitrates 106-113 inducible nitrate reductase [NADH] 1 Glycine max 46-48 16664642-6 1986 Stem NO(3) (-) concentration and in vivo leaf NR activity were significantly correlated (R(2) = 0.69 with nitrate in the assay medium and 0.74 without nitrate in the medium at P = 0.001) across six combinations of reproductive and soil N-treatment. Nitrates 151-158 inducible nitrate reductase [NADH] 1 Glycine max 46-48 3955002-4 1986 All of the ligands except for the halides, nitrate, and acetate form exclusively low-spin complexes in analogy to results obtained with the spectroscopically related protein, cytochrome P-450-CAM [Sono, M., & Dawson, J.H. Nitrates 43-50 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 175-191 3754852-0 1986 The binding of plutonium to transferrin in the presence of tri-n-butyl phosphate or nitrate and its release by diethylenetriaminepenta-acetate and the tetrameric catechoylamide ligand LICAMC(C). Nitrates 84-91 transferrin Homo sapiens 28-39 11538660-5 1986 The nuclear NTPase activity was not inhibited by vanadate, oligomycin, or nitrate, but was inhibited by relatively low concentrations of quercetin and the calmodulin inhibitor, compound 48/80. Nitrates 74-81 inosine triphosphatase Homo sapiens 12-18 6372319-0 1983 Nitrate reduction in so-called nitrate reductase (NR) negative strains of the genus Mycobacterium. Nitrates 0-7 GR01_RS13310 Mycobacterium chelonae 31-48 3926614-7 1985 The effect of the nitrates on the venous capacitance system is reflected by the increase in the PEP/LVET ratio where NTGO and NTGB elicited marked actions and those of sustained-release ISDN and IS 5-MN were of a lesser extent. Nitrates 18-26 progestagen associated endometrial protein Homo sapiens 96-99 16664208-6 1985 Nitrate supply was therefore implicated as limiting to leaf NR activity during the decline associated with flowering and early seed development. Nitrates 0-7 inducible nitrate reductase [NADH] 1 Glycine max 60-62 16664208-8 1985 As no significant increase in leaf NR activity was observed in response to light enhancement alone, leaf nitrate supply was further implicated as more limiting to leaf NR activity than was photosynthate supply during flowering and early seed development. Nitrates 105-112 inducible nitrate reductase [NADH] 1 Glycine max 168-170 16664214-5 1985 Nitrate-grown nr(1) mutant soybean plants yielded a NADH:nitrate reductase (designated iNR) when Blue Sepharose columns were eluted with NADH; NADPH failed to elute any NR form from Blue Sepharose loaded with this extract. Nitrates 0-7 chalcone reductase CHR1 Glycine max 65-74 16664214-10 1985 The iNR preferred NADH over NADPH and had an apparent Michaelis constant of 0.13 millimolar for nitrate.Thus, wild-type soybean contains two forms of constitutive nitrate reductase, both differing in their physical properties from nitrate reductases common in higher plants. Nitrates 96-103 chalcone reductase CHR1 Glycine max 171-180 4089329-0 1985 [Environmental nitrates and the experimental formation of methemoglobin]. Nitrates 15-23 hemoglobin subunit gamma 2 Homo sapiens 58-71 4022112-0 1985 Determination of nitrates in milk by ion-chromatography. Nitrates 17-25 Weaning weight-maternal milk Bos taurus 29-33 4022112-1 1985 A method is described for the determination of nitrates in cow milk, human milk, milk powder or milk-based infant formulae using liquid chromatography on Spheron DEAE and a direct photometric detection (205 nm). Nitrates 47-55 Weaning weight-maternal milk Bos taurus 63-67 4022112-1 1985 A method is described for the determination of nitrates in cow milk, human milk, milk powder or milk-based infant formulae using liquid chromatography on Spheron DEAE and a direct photometric detection (205 nm). Nitrates 47-55 Weaning weight-maternal milk Bos taurus 75-79 4022112-1 1985 A method is described for the determination of nitrates in cow milk, human milk, milk powder or milk-based infant formulae using liquid chromatography on Spheron DEAE and a direct photometric detection (205 nm). Nitrates 47-55 Weaning weight-maternal milk Bos taurus 75-79 4022112-1 1985 A method is described for the determination of nitrates in cow milk, human milk, milk powder or milk-based infant formulae using liquid chromatography on Spheron DEAE and a direct photometric detection (205 nm). Nitrates 47-55 Weaning weight-maternal milk Bos taurus 75-79 16663186-5 1983 Nitrate assimilation (nitrate reductase activity and total accumulation of reduced-N) was also enhanced in response to vegetative apex removal. Nitrates 0-7 inducible nitrate reductase [NADH] 1 Glycine max 22-39 6613236-8 1983 SIN 1 effectively dilates nonstenotic and especially stenotic epicardial coronary arteries, as it is already known for nitrates and calcium-channel blockers. Nitrates 119-127 MAPK associated protein 1 Homo sapiens 0-5 16662876-5 1983 Inasmuch as nitrate reduction results in the production of OH(-) and stimulates the synthesis of organic anions, it was postulated that nitrate reductase activity of roots is stimulated by the released OH(-) or by the synthesized organic anions rather than by nitrate itself. Nitrates 12-19 nitrate reductase [NADH] 1 Zea mays 136-153 16664862-5 1986 In vitro FMNH(2)-dependent nitrate reduction and Cyt c reductase activity of nitrate-grown plants, and nitrogenous gas evolution during in vivo NR assays of urea-grown plants, were also decreased in the mutants. Nitrates 77-84 chalcone reductase CHR1 Glycine max 55-64 24241316-3 1985 By using darkened or illuminated leaves in the absence or presence of nitrate, it has been confirmed that nitrate is required in the in-vivo synthesis of NiR and that this synthesis is stimulated by light. Nitrates 106-113 ferredoxin--nitrite reductase, chloroplastic Triticum aestivum 154-157 24241316-8 1985 Nitrate appears to regulate NiR synthesis by triggering transcription whereas the light may control the level of transcription or translation. Nitrates 0-7 ferredoxin--nitrite reductase, chloroplastic Triticum aestivum 28-31 18963604-2 1984 The differential pulse polarographic peak-height is proportional to nitrate concentration from 1 to 50 muM. Nitrates 68-75 latexin Homo sapiens 103-106 6427300-0 1984 Methemoglobin levels produced by organic nitrates in patients with coronary artery disease. Nitrates 41-49 hemoglobin subunit gamma 2 Homo sapiens 0-13 6427300-1 1984 To determine if ordinary doses of nitrates produce a significant increase in methemoglobin, methemoglobin levels were measured in 59 randomly selected patients with coronary artery disease and unstable angina pectoris who were receiving organic nitrate therapy. Nitrates 34-42 hemoglobin subunit gamma 2 Homo sapiens 77-90 6427300-1 1984 To determine if ordinary doses of nitrates produce a significant increase in methemoglobin, methemoglobin levels were measured in 59 randomly selected patients with coronary artery disease and unstable angina pectoris who were receiving organic nitrate therapy. Nitrates 34-42 hemoglobin subunit gamma 2 Homo sapiens 92-105 6427300-1 1984 To determine if ordinary doses of nitrates produce a significant increase in methemoglobin, methemoglobin levels were measured in 59 randomly selected patients with coronary artery disease and unstable angina pectoris who were receiving organic nitrate therapy. Nitrates 34-41 hemoglobin subunit gamma 2 Homo sapiens 77-90 6427300-1 1984 To determine if ordinary doses of nitrates produce a significant increase in methemoglobin, methemoglobin levels were measured in 59 randomly selected patients with coronary artery disease and unstable angina pectoris who were receiving organic nitrate therapy. Nitrates 34-41 hemoglobin subunit gamma 2 Homo sapiens 92-105 6427300-7 1984 It is concluded that commonly used dosages of nitrates are capable of causing elevations of methemoglobin which are probably not of routine clinical significance. Nitrates 46-54 hemoglobin subunit gamma 2 Homo sapiens 92-105 6372319-0 1983 Nitrate reduction in so-called nitrate reductase (NR) negative strains of the genus Mycobacterium. Nitrates 0-7 GR01_RS13310 Mycobacterium chelonae 50-52 6141677-6 1983 In the presence of the vital stain methylene blue - which was shown in vitro to prevent nitrate-induced activation of guanylate cyclase, the enzyme which forms cGMP from GTP - the relaxant actions as well as the increases in cGMP produced by several of these nitro-compounds in coronary strips were almost abolished. Nitrates 88-95 guanylate cyclase Bos taurus 118-135 16662417-4 1982 Correlations between nitrate or nitrite concentration in nodules and nodule weight/plant were highly significant.Cytosol from soybean nodules was found to contain NADH-dependent nitrate reductase activity (typical activity was 0.1 micromole per milligram protein x hour). Nitrates 21-28 chalcone reductase CHR1 Glycine max 186-195 6874197-7 1983 Clearly elevated nitrate contents were revealed by the resuls of measurements: 13% of samples showed values above the maximal concentration admissible under the EC Drinking Water Directive of 50 mg NO-3/l and 42% above the EC guide level. Nitrates 17-24 NBL1, DAN family BMP antagonist Homo sapiens 198-202 17791587-1 1982 Fog water collected at three sites in Los Angeles and Bakersfield, California, was found to have higher acidity and higher concentrations of sulfate, nitrate, and ammonium than previously observed in atmospheric water droplets. Nitrates 150-157 zinc finger protein, FOG family member 1 Homo sapiens 0-3 16346140-1 1982 Bacteria able to perform dissimilatory nitrate reduction to ammonium were isolated from low-oxygen masses in the Baltic Sea. Nitrates 39-46 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 120-123 16662475-0 1982 Differential effect of tungsten on the development of endogenous and nitrate-induced nitrate reductase activities in soybean leaves. Nitrates 69-76 inducible nitrate reductase [NADH] 1 Glycine max 85-102 16662475-1 1982 The effect of tungsten on the development of endogenous and nitrate-induced NADH- and FMNH(2)-linked nitrate reductase activities in primary leaves of 10-day-old soybean (Glycine max [L.] Merr.) Nitrates 60-67 chalcone reductase CHR1 Glycine max 109-118 16662475-4 1982 High levels of endogenous nitrate reductase activities developed in leaves of seedlings grown without nitrate. Nitrates 26-33 chalcone reductase CHR1 Glycine max 34-43 16662475-8 1982 By contrast, in nitrate-grown seedlings, tungsten only inhibited the nitrate-induced portion of NADH-linked nitrate reductase activity, whereas the FMNH(2)-linked activity was inhibited completely. Nitrates 69-76 chalcone reductase CHR1 Glycine max 116-125 16662475-10 1982 The complete inhibition of FMNH(2)-linked nitrate reductase activity by tungsten in nitrate-grown plants was apparently an artifact caused by the reduction of nitrite by nitrite reductase in the assay system. Nitrates 42-49 chalcone reductase CHR1 Glycine max 50-59 16662475-10 1982 The complete inhibition of FMNH(2)-linked nitrate reductase activity by tungsten in nitrate-grown plants was apparently an artifact caused by the reduction of nitrite by nitrite reductase in the assay system. Nitrates 42-49 chalcone reductase CHR1 Glycine max 178-187 16662475-11 1982 The results suggest that in soybean leaves either the endogenous nitrate reductase does not require molybdenum or the molybdenum present in the seed is preferentially utilized by the enzyme complex as compared to nitrate-induced nitrate reductase. Nitrates 65-72 chalcone reductase CHR1 Glycine max 73-82 6749995-2 1982 The method involves a sandwich technique in which antiserum to human IgE is adsorbed on a cellulose acetate/nitrate disc which is attached to a plastic StiQTM sampler. Nitrates 108-115 immunoglobulin heavy constant epsilon Homo sapiens 69-72 7135816-7 1982 The amount of blood methemoglobin was found to correlate directly with the percent of nitrates in the ration. Nitrates 86-94 hemoglobin subunit gamma 2 Homo sapiens 20-33 16662417-6 1982 Growth of nodules formed by the mutant lacking nitrate reductase was inhibited by nitrate. Nitrates 47-54 chalcone reductase CHR1 Glycine max 55-64 24276702-0 1981 Glutamine synthetase of Chlamydomonas: its role in the control of nitrate assimilation. Nitrates 66-73 glutamate-ammonia ligase Homo sapiens 0-20 16662109-3 1981 Biosynthetic glutamine synthetase activity was 1.5 to 1.8 times greater in nitrogen-limited cells than cells grown at high levels of the three nitrogen sources.Conversely, glutamate dehydrogenase (both NADH- and NADPH-dependent activities) was greatest in cells grown at high levels of asparagine or ammonium, while nitrate-grown cells possessed little activity at all concentrations employed. Nitrates 316-323 glutamate-ammonia ligase Homo sapiens 13-33 16345884-6 1981 Anaerobic treatment of RDX wastewaters, which also contain high nitrate levels, would permit the denitrification to occur, with concurrent degradation of RDX ultimately to a mixture of hydrazines and methanol. Nitrates 64-71 radixin Homo sapiens 23-26 6973419-6 1981 Coronary artery bypass grafting in a subgroup of patients did not affect the mean plasma PF4 concentration during 1 year of follow-up after bypass surgery, but medical therapy for angina with increasing doses of propranolol and nitrates significantly reduced PF4 concentration in another subgroup of patients who were not considered to be candidates for surgical therapy. Nitrates 228-236 platelet factor 4 Homo sapiens 259-262 7306876-9 1981 This agrees well with the nitrate partitioning observed by the acetylene inhibition method in which 30--40% of the NO3- -N was recovered as N2O. Nitrates 26-33 NBL1, DAN family BMP antagonist Homo sapiens 115-118 16661906-3 1981 The nitrate-free in vivo assay system of nitrate reductase was used for measuring the production of nitrite. Nitrates 4-11 chalcone reductase CHR1 Glycine max 49-58 7209517-1 1981 Radioactive nitrogen-13 from nitrite (NO2-) or nitrate (NO3-) administered intratracheally or intravenously without added carrier to mice or rabbits was distributed evenly throughout most organs and tissues regardless of the entry route or the anion administered. Nitrates 47-54 NBL1, DAN family BMP antagonist Mus musculus 56-59 6975421-7 1981 BV1 differs from B. gazogenes in cell size, pattern of pigment production, nutritional characteristics, the ability to perform anaerobic respiration using nitrate as a terminal electron acceptor, sensitivity to a newly discovered lytic phage and to the antibiotic vibriostat O/129. Nitrates 155-162 endogenous ecotropic MuLV 2 Mus musculus 0-3 6459097-0 1981 The dose of nicorandil in men predicted from the inhibition of MAO activity by organic nitrates. Nitrates 87-95 monoamine oxidase A Rattus norvegicus 63-66 16661493-4 1980 Cells which survived the chlorate treatment then were transferred to casein hydrolysate medium and have been cultured in the absence of chlorate for more than 18 months (NR1).DI-6 cells can grow in a nitrate-based medium, whereas NR1 cells can take up nitrate but cannot use it as a N source. Nitrates 200-207 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 170-173 7269804-3 1981 When the alimentary nitrate intake is in the range of 50 mg NO3- the nitrate values in saliva of adults and children follow a Gaussian normal distribution. Nitrates 20-27 NBL1, DAN family BMP antagonist Homo sapiens 60-63 7269804-3 1981 When the alimentary nitrate intake is in the range of 50 mg NO3- the nitrate values in saliva of adults and children follow a Gaussian normal distribution. Nitrates 69-76 NBL1, DAN family BMP antagonist Homo sapiens 60-63 16661600-4 1980 Increases in nitrate supply resulted in decreases in nitrate reductase activity and negligible increases in reduced N in the roots of both hybrids. Nitrates 13-20 nitrate reductase [NADH] 1 Zea mays 53-70 16661600-6 1980 Hybrid B also had lower nitrate reductase activity at all levels of external nitrate and accumulated less reduced N than did hybrid C, except when the plants were grown at 2.5 millimolar nitrate. Nitrates 77-84 nitrate reductase [NADH] 1 Zea mays 24-41 16661493-4 1980 Cells which survived the chlorate treatment then were transferred to casein hydrolysate medium and have been cultured in the absence of chlorate for more than 18 months (NR1).DI-6 cells can grow in a nitrate-based medium, whereas NR1 cells can take up nitrate but cannot use it as a N source. Nitrates 200-207 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 230-233 16661493-5 1980 The inability of NR1 to assimilate nitrate appears to be due to the lack of an active nitrate reductase in these cells. Nitrates 35-42 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 17-20 16661493-6 1980 Through the use of a variety of electron donors and acceptors, the lack of nitrate reductase activity in NR1 cells was shown to be due to the absence of, or a defect in, that component of the enzyme which mediates the reduction of nitrate to nitrite.In other experiments, DI-6 and NR1 were grown on a solid medium containing casein hydrolysate (2 grams liter(-1)) as the sole N source. Nitrates 75-82 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 105-108 16661493-6 1980 Through the use of a variety of electron donors and acceptors, the lack of nitrate reductase activity in NR1 cells was shown to be due to the absence of, or a defect in, that component of the enzyme which mediates the reduction of nitrate to nitrite.In other experiments, DI-6 and NR1 were grown on a solid medium containing casein hydrolysate (2 grams liter(-1)) as the sole N source. Nitrates 75-82 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 281-284 16345620-1 1980 During microaerophilic growth of magnetic spirillum MS-1 on tartrate and nitrate, a maximal cell density was obtained at an initial oxygen partial pressure of 17 Pa. A transient accumulation of nitrous oxide and a 1:2 (mol/mol) stoichiometry between tartrate oxidation and nitrate reduction were observed, indicating that the organism carried out a respiratory type of metabolism. Nitrates 73-80 MS Homo sapiens 52-56 16345620-1 1980 During microaerophilic growth of magnetic spirillum MS-1 on tartrate and nitrate, a maximal cell density was obtained at an initial oxygen partial pressure of 17 Pa. A transient accumulation of nitrous oxide and a 1:2 (mol/mol) stoichiometry between tartrate oxidation and nitrate reduction were observed, indicating that the organism carried out a respiratory type of metabolism. Nitrates 273-280 MS Homo sapiens 52-56 16661380-9 1980 From the patterns of plant nitrate content it was deduced that the low nitrate reductase genotypes terminated nitrate absorption sooner than the high nitrate reductase types. Nitrates 27-34 nitrate reductase [NADH] 1 Zea mays 71-88 7374672-6 1980 The rate constant k2 was temperature-dependent with a Q10 of 1.11 between 5 degrees C and 30 degrees C. Aromatic carboxylic acids known to block sarcolemmal Cl conductance (GCl) specifically lowered k2 by 25% at 30 degrees C, as did replacement of external Cl with nitrate. Nitrates 265-272 germ cell-less 2, spermatogenesis associated Homo sapiens 173-176 16661245-7 1980 Assays of the NADPH-eluted NR with different concentrations of nitrate revealed that the highest activity was obtained in 80 millimolar KNO(3). Nitrates 63-70 inducible nitrate reductase [NADH] 1 Glycine max 27-29 16661245-8 1980 Thus, this fraction has properties similar to the low nitrate affinity NAD(P)H:NR of soybean leaves. Nitrates 54-61 inducible nitrate reductase [NADH] 1 Glycine max 79-81 16661245-10 1980 Assays of this fraction with different nitrate concentrations revealed that this NR had a higher nitrate affinity and was similar to the NADH:NR of soybean leaves. Nitrates 39-46 inducible nitrate reductase [NADH] 1 Glycine max 81-83 16661245-10 1980 Assays of this fraction with different nitrate concentrations revealed that this NR had a higher nitrate affinity and was similar to the NADH:NR of soybean leaves. Nitrates 97-104 inducible nitrate reductase [NADH] 1 Glycine max 81-83 6986356-4 1980 Alcohol dehydrogenase production was largely unaffected by catabolite repression but was repressed by nitrate under both aerobic and anaerobic conditions. Nitrates 102-109 Alcohol dehydrogenase Escherichia coli 0-21 629538-0 1978 Induction of a dissimilatory reduction pathway of nitrate in Halobacterium of the Dead Sea. Nitrates 50-57 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 87-90 16660571-6 1978 Because the specific activity of nitrate reductase was severalfold lower than the other enzymes involved in nitrate assimilation, nitrate reduction is indicated as the rate-limiting step in situ. Nitrates 108-115 nitrate reductase [NADH] 1 Zea mays 33-50 16660485-15 1978 The inhibition of nitrate reductase was noncompetitive with nitrate but caused a decrease in V(max).The isolated inhibitor was inactivated in the light, but after 24 hours in the dark full inhibitory activity returned. Nitrates 18-25 chalcone reductase CHR1 Glycine max 26-35 868388-1 1977 Ultraviolet light (PRK-2) induces the formation of various amino acids (lysine, asparaginic, as well as traces of some other acids) in mannose, glucose and arabinose solutions containing various nitrates. Nitrates 195-203 protein kinase N2 Homo sapiens 19-24 15657-1 1977 A highly purified preparation of glutamine synthetase from chlorella grown on a medium containing nitrate as a sole source of nitrogen, was isolated and characterized by disc-electrophoresis and analytical ultracentrifugation. Nitrates 98-105 glutamate-ammonia ligase Homo sapiens 33-53 5557824-0 1971 [Regulation of plant glutamine synthetase by ammonium and nitrate]. Nitrates 58-65 glutamate-ammonia ligase Homo sapiens 21-41 2016-2 1975 Maximal levels of free water clearance/clomerular filtration rate (CH2O/GFR) averaged 8.4% with nitrate loading and 14.4% with saline loading. Nitrates 96-103 Rap guanine nucleotide exchange factor 5 Homo sapiens 67-75 170914-6 1975 The significance of the enzyme in conjunction with glutamine synthetase in the assimilation of nitrate by roots is discussed. Nitrates 95-102 glutamate-ammonia ligase Homo sapiens 51-71 236776-2 1975 Also dithionite, used to reduce benzylviologen and FMN, inactivates nitrate reductase: however, FMN at an optimal concentration and nitrate, added before the dithionite, protect the enzyme against this inactivation. Nitrates 68-75 formin 1 Homo sapiens 51-54 236776-2 1975 Also dithionite, used to reduce benzylviologen and FMN, inactivates nitrate reductase: however, FMN at an optimal concentration and nitrate, added before the dithionite, protect the enzyme against this inactivation. Nitrates 68-75 formin 1 Homo sapiens 96-99 24430370-2 1975 over the growing season.The level of nitrate-reductase activity generally paralleled the concentration of nitrate in the leaf tissue over the entire growing season. Nitrates 37-44 chalcone reductase CHR1 Glycine max 45-54 16658530-1 1973 In a study on 3-day maize (Zea mays) seedlings, grown on nitrate, requirements were established for the maximum extraction and optimum stabilization of nitrate reductase in vitro. Nitrates 57-64 nitrate reductase [NADH] 1 Zea mays 152-169 16658530-6 1973 A high level of nitrate (approximately 100 mm) was required to saturate the induction of nitrate reductase in the root tip, mature root, and scutellum. Nitrates 16-23 nitrate reductase [NADH] 1 Zea mays 89-106 16658530-7 1973 The concentration of nitrate required to give half the maximum level of enzyme induced was the same for each region (29 mm).After leaf expansion, more than 90% of the nitrate reductase was in the shoot, mainly in the leaf blade, and a marked decrease occurred in the level of the enzyme in the scutellum. Nitrates 21-28 nitrate reductase [NADH] 1 Zea mays 167-184 16658531-10 1973 The activity of the nitrate reductase inactivating enzyme was not influenced by nitrate and was also found in the mature root of minus nitrate-grown seedlings. Nitrates 80-87 nitrate reductase [NADH] 1 Zea mays 20-37 16658419-3 1973 Experiments were conducted to determine whether the decrease in nitrate reductase activity was due to reduced levels of nitrate in the tissue, direct inactivation of the enzyme by low leaf water potentials, or to changes in rates of synthesis or decay of the enzyme.Although tissue nitrate content decreased with the onset of desiccation, it did not continue to decline with tissue desiccation and loss of enzyme activity. Nitrates 120-127 nitrate reductase [NADH] 1 Zea mays 64-81 16658419-4 1973 Nitrate reductase activity recovered when the plants were rewatered with nitrate-free medium, suggesting that the nitrate in the plant was adequate for high nitrate reductase activity. Nitrates 73-80 nitrate reductase [NADH] 1 Zea mays 0-17 16658419-4 1973 Nitrate reductase activity recovered when the plants were rewatered with nitrate-free medium, suggesting that the nitrate in the plant was adequate for high nitrate reductase activity. Nitrates 73-80 nitrate reductase [NADH] 1 Zea mays 157-174 16658419-4 1973 Nitrate reductase activity recovered when the plants were rewatered with nitrate-free medium, suggesting that the nitrate in the plant was adequate for high nitrate reductase activity. Nitrates 114-121 nitrate reductase [NADH] 1 Zea mays 0-17 16658419-4 1973 Nitrate reductase activity recovered when the plants were rewatered with nitrate-free medium, suggesting that the nitrate in the plant was adequate for high nitrate reductase activity. Nitrates 114-121 nitrate reductase [NADH] 1 Zea mays 157-174 5068711-0 1972 Methemoglobin levels in infants in an area with high nitrate water supply. Nitrates 53-60 hemoglobin subunit gamma 2 Homo sapiens 0-13 16657912-4 1972 Soybean contains an active nitrate reductase in roots and leaves, but the low specific activity of this enzyme in sunflower leaves indicates a dependency upon the roots for nitrate reduction. Nitrates 27-34 chalcone reductase CHR1 Glycine max 35-44 16657912-6 1972 Nitrate reductase activity in leaves of nitrate-supplied soybean and sunflower follows closely the distribution of nitrate reductase. Nitrates 40-47 inducible nitrate reductase [NADH] 1 Glycine max 0-17 16657912-6 1972 Nitrate reductase activity in leaves of nitrate-supplied soybean and sunflower follows closely the distribution of nitrate reductase. Nitrates 40-47 chalcone reductase CHR1 Glycine max 8-17 16657913-6 1972 Nitrate roots also maintain a high level of NADPH, presumably by the stimulatory effect of nitrate utilization on glucose-6-phosphate dehydrogenase activity. Nitrates 0-7 glucose-6-phosphate dehydrogenase Glycine max 114-147 16657913-6 1972 Nitrate roots also maintain a high level of NADPH, presumably by the stimulatory effect of nitrate utilization on glucose-6-phosphate dehydrogenase activity. Nitrates 91-98 glucose-6-phosphate dehydrogenase Glycine max 114-147 16657914-9 1972 Maximum total activity shifted to leaf positions lower in the plant canopy with later growth stages.Nitrate reductase activity of soybeans grown in hydroponic systems was significantly higher than activity of adjacent soil grown plants at later growth stages, which suggested that under normal field conditions the potential for nitrate utilization may not be realized. Nitrates 329-336 inducible nitrate reductase [NADH] 1 Glycine max 100-117 4397909-0 1971 The development of methemoglobin in mothers and newborn infants from nitrate in water supplies. Nitrates 69-76 hemoglobin subunit gamma 2 Homo sapiens 19-32 11898-1 1976 Each mole of oxyhemoglobin iron converted to methemoglobin causes the oxidation of 1.5 mol of nitrite to nitrate and consumes 1 mol of protons. Nitrates 105-112 hemoglobin subunit gamma 2 Homo sapiens 45-58 16659754-2 1976 Decreases in leaf nitrate supply were associated with decreases in induction of nitrate reductase, thus supporting the view that the influx of nitrate to a tissue is a major factor in regulation of the level of nitrate reductase. Nitrates 18-25 nitrate reductase [NADH] 1 Zea mays 80-97 16659754-2 1976 Decreases in leaf nitrate supply were associated with decreases in induction of nitrate reductase, thus supporting the view that the influx of nitrate to a tissue is a major factor in regulation of the level of nitrate reductase. Nitrates 18-25 nitrate reductase [NADH] 1 Zea mays 211-228 16659754-2 1976 Decreases in leaf nitrate supply were associated with decreases in induction of nitrate reductase, thus supporting the view that the influx of nitrate to a tissue is a major factor in regulation of the level of nitrate reductase. Nitrates 80-87 nitrate reductase [NADH] 1 Zea mays 211-228 16659756-4 1976 were designed to determine the relative limitations of NO(3) (-), NADH, and nitrate reductase (NR) per se on nitrate metabolism as affected by light and temperature. Nitrates 76-83 inducible nitrate reductase [NADH] 1 Glycine max 95-97 184842-6 1976 The proportion of the cytochrome c which is reduced during the second stage is oxidizable by either nitrate or H2O2 and is reduced again when the nitrate or H2O2 have been depleted. Nitrates 100-107 cytochrome c, somatic Homo sapiens 22-34 184842-6 1976 The proportion of the cytochrome c which is reduced during the second stage is oxidizable by either nitrate or H2O2 and is reduced again when the nitrate or H2O2 have been depleted. Nitrates 146-153 cytochrome c, somatic Homo sapiens 22-34 16659704-2 1976 The roles that leaf nitrate content and nitrate flux play in regulating the levels of nitrate reductase activity (NRA) were investigated in 8- to 14-day old maize (Zea mays L.) plants containing high nitrate levels while other environmental and endogenous factors were constant. Nitrates 20-27 nitrate reductase [NADH] 1 Zea mays 86-103 16659704-2 1976 The roles that leaf nitrate content and nitrate flux play in regulating the levels of nitrate reductase activity (NRA) were investigated in 8- to 14-day old maize (Zea mays L.) plants containing high nitrate levels while other environmental and endogenous factors were constant. Nitrates 40-47 nitrate reductase [NADH] 1 Zea mays 86-103 16659704-2 1976 The roles that leaf nitrate content and nitrate flux play in regulating the levels of nitrate reductase activity (NRA) were investigated in 8- to 14-day old maize (Zea mays L.) plants containing high nitrate levels while other environmental and endogenous factors were constant. Nitrates 40-47 nitrate reductase [NADH] 1 Zea mays 86-103 983544-1 1976 Daily intake of nitrate and nitrate by German Federal Republic resident was calculated to 75 mg NO3- and 3.3 mg NO2-. Nitrates 16-23 NBL1, DAN family BMP antagonist Homo sapiens 96-99 983544-1 1976 Daily intake of nitrate and nitrate by German Federal Republic resident was calculated to 75 mg NO3- and 3.3 mg NO2-. Nitrates 28-35 NBL1, DAN family BMP antagonist Homo sapiens 96-99 16659360-5 1975 The response to glucose is seen over a wide range of external NO(3) (-) concentrations.Nitrate reductase activity is lost rapidly when nitrate is withdrawn from the induction medium. Nitrates 135-142 nitrate reductase [NADH] 1 Zea mays 87-104 16659373-6 1975 The pattern of induction of nitrate reductase was coincident with the pattern of nitrate uptake as a function of time and increasing nitrate concentrations. Nitrates 81-88 nitrate reductase [NADH] 1 Zea mays 28-45 16659373-7 1975 The rate of induction of nitrate reductase was regulated by the rate of nitrate flux.Washing the roots for 2 hours enhances nitrate uptake by 2.5-fold over the nonwashed tissue. Nitrates 72-79 nitrate reductase [NADH] 1 Zea mays 25-42 4396143-2 1971 The purified enzyme was specific for NADPH and catalyzed reduction of nitrate, cytochrome c from isolated mitochondria of Aspergillus, and mammalian cytochrome c. Nitrates 70-77 cytochrome c, somatic Homo sapiens 149-161 16657550-1 1970 Nitrate reductase activity was induced by nitrate in green corn (Zea mays) leaves in either light or darkness. Nitrates 42-49 nitrate reductase [NADH] 1 Zea mays 0-17 4993525-0 1970 [Effect of nitrates in products of vegetable origin on methemoglobin formation]. Nitrates 11-19 hemoglobin subunit gamma 2 Homo sapiens 55-68 4393266-1 1970 In vitro assembly or complementation of a hybrid assimilatory nitrate reductase was attained by mixing a preparation of nitrate-induced N. crassa mutant nit-1 specifically with acid-treated (pH 2.5) bovine milk or intestinal xanthine oxidase, rabbit liver aldehyde oxidase, or chicken liver xanthine dehydrogenase. Nitrates 62-69 xanthine dehydrogenase Gallus gallus 291-313 17774405-1 1968 The interrelations and time-dependence of nitrate, nitrite, and ammonia in a deep basin of the Baltic Sea yield a measurement of stagnation history and may provide a means of prediction of resupply of nutrients to the upper productive layers. Nitrates 42-49 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 102-105 16742412-11 1966 Nitrite reductase is induced by nitrite and only indirectly by nitrate. Nitrates 63-70 ferredoxin--nitrite reductase, chloroplastic Raphanus sativus 0-17 20294121-0 1947 Studies on reactions relating to carbohydrates and polysaccharides; effect of hot alkali on the nitrates of starch, amylose, and amylopectin. Nitrates 96-104 alcohol dehydrogenase iron containing 1 Homo sapiens 78-81 33743462-2 2021 In this study, a three-dimensional model of a large coal waste rock dump constructed in the Elk Valley, British Columbia, Canada was developed to capture the impact of construction history (1981-2012) and solute transport on nitrate (NO3-) release over a 100-year timeframe. Nitrates 225-232 NBL1, DAN family BMP antagonist Homo sapiens 234-237 33990989-2 2021 By employing ab initio molecular dynamics (AIMD) method, we studied the effects of the proton transfer and the rotation of the nitrates on the vibrational profiles of HNO3 (NO3 - )(H2 O)n (n = 0-2). Nitrates 127-135 NBL1, DAN family BMP antagonist Homo sapiens 168-171 33736152-6 2021 Organic aerosol (OA) and sulfate were dominant contributor of PM1 in summer, whereas OA and nitrate primarily contribution to the increase of PM1 mass loading in spring and winter. Nitrates 92-99 transmembrane protein 11 Homo sapiens 142-145 34050740-4 2021 Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth. Nitrates 133-140 Plant regulator RWP-RK family protein Arabidopsis thaliana 33-37 34050740-4 2021 Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth. Nitrates 133-140 NIN like protein 7 Arabidopsis thaliana 42-46 34050740-4 2021 Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth. Nitrates 133-140 Plant regulator RWP-RK family protein Arabidopsis thaliana 186-190 34050740-7 2021 Importantly, nitrate utilization was almost completely abolished in the nlp septuple mutant (nlp2 nlp4 nlp5 nlp6 nlp7 nlp8 nlp9), suggesting that NLPs other than NLP2 and NLP7 also assist in the regulation of nitrate-inducible gene expression and nitrate-dependent promotion of vegetative growth in Arabidopsis. Nitrates 13-20 Plant regulator RWP-RK family protein Arabidopsis thaliana 93-97 34050740-7 2021 Importantly, nitrate utilization was almost completely abolished in the nlp septuple mutant (nlp2 nlp4 nlp5 nlp6 nlp7 nlp8 nlp9), suggesting that NLPs other than NLP2 and NLP7 also assist in the regulation of nitrate-inducible gene expression and nitrate-dependent promotion of vegetative growth in Arabidopsis. Nitrates 13-20 Plant regulator RWP-RK family protein Arabidopsis thaliana 162-166 34050740-7 2021 Importantly, nitrate utilization was almost completely abolished in the nlp septuple mutant (nlp2 nlp4 nlp5 nlp6 nlp7 nlp8 nlp9), suggesting that NLPs other than NLP2 and NLP7 also assist in the regulation of nitrate-inducible gene expression and nitrate-dependent promotion of vegetative growth in Arabidopsis. Nitrates 13-20 NIN like protein 7 Arabidopsis thaliana 171-175 34043471-7 2021 In skeletal muscle, nitrate treatment upregulated expression of genes central to nutrient sensing (mtor), redox signaling (nrf2a) and muscle differentiation (sox6). Nitrates 20-27 nfe2 like bZIP transcription factor 2a Danio rerio 123-128 34043471-7 2021 In skeletal muscle, nitrate treatment upregulated expression of genes central to nutrient sensing (mtor), redox signaling (nrf2a) and muscle differentiation (sox6). Nitrates 20-27 SRY-box transcription factor 6 Danio rerio 158-162 34038101-2 2021 The balance of water coordination and the multitude of bonding of the weakly coordinated nitrate lead to a progressive change in the coordination number of the Cd2+ ions from eight to seven to six without great perturbation to the 4-fold interpenetration three-dimensional framework. Nitrates 89-96 CD2 molecule Homo sapiens 160-163 33482555-1 2021 The effective control and management of nitrate (NO3-) pollution requires the identification of the sources of NO3- pollution in groundwater and quantification of their contribution rates. Nitrates 40-47 NBL1, DAN family BMP antagonist Homo sapiens 49-52 33482555-1 2021 The effective control and management of nitrate (NO3-) pollution requires the identification of the sources of NO3- pollution in groundwater and quantification of their contribution rates. Nitrates 40-47 NBL1, DAN family BMP antagonist Homo sapiens 111-114 33982797-9 2021 Nitrate-containing versus placebo juice significantly lowered CIMT [-0.06 (95% Confidence Interval -0.12, -0.01), p=0.034], an overall difference of ~8% relative to baseline; but had no effect on carotid diameter (CD) or carotid stiffness (CS). Nitrates 0-7 CIMT Homo sapiens 62-66 33966117-6 2021 At 90% WHC, Met + C treatment significantly lessened concentrations of NH4+ and NO3-, nonetheless improved N2O compared to Met treatment. Nitrates 80-84 SAFB like transcription modulator Homo sapiens 12-15 33963398-6 2021 Moreover, higher photorespiration and nitrate accumulation were determined in these plants relative to the untransformed control, indicating that overexpression of Trx m favors the photorespiratory N cycle rather than primary nitrate assimilation. Nitrates 38-45 thioredoxin H-type 1 Nicotiana tabacum 164-167 34025702-10 2021 A key indicator of biostimulant performance was increased nitrate content in barley shoot tissue 22 days after N fertilizer application (+17.9-72.2%), that was associated with gene upregulation of root nitrate transporters (NRT1.1, NRT2.1, and NRT1.5). Nitrates 58-65 putative low affinity nitrate transporter Hordeum vulgare 224-228 33903869-1 2021 Herein, we describe the nonlinear processes for the formation of thin films of the PbS-CdS system using chemical bath deposition with a gradual change in the cadmium nitrate content in the reaction mixture. Nitrates 166-173 cholinergic receptor muscarinic 3 Homo sapiens 83-86 33758916-3 2021 Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3. Nitrates 152-159 nitrate transporter 2:1 Arabidopsis thaliana 179-183 33758916-3 2021 Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3. Nitrates 152-159 nitrate transporter2.5 Arabidopsis thaliana 187-193 33758916-5 2021 First, HHOs directly repress the high-affinity nitrate transporters, NRT2.4 and NRT2.5. Nitrates 47-54 nitrate transporter 2:1 Arabidopsis thaliana 69-73 33831352-3 2021 Here, we discovered that, independent of nitrogen assimilation, nitrate and ammonium function as primary nitrogen signals to activate TOR in the Arabidopsis leaf primordium. Nitrates 64-71 target of rapamycin Arabidopsis thaliana 134-137 33831352-5 2021 Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions. Nitrates 15-22 RHO-related protein from plants 2 Arabidopsis thaliana 113-117 33831352-5 2021 Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions. Nitrates 15-22 RHO-related protein from plants 2 Arabidopsis thaliana 146-150 33831352-5 2021 Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions. Nitrates 15-22 target of rapamycin Arabidopsis thaliana 160-163 33601051-3 2021 We report here that a cyclic nucleotide-gated channel (CNGC) protein, CNGC15, and the nitrate transceptor (NRT1.1) constitute a molecular switch that controls calcium influx depending on nitrate levels. Nitrates 86-93 nitrate transporter 1.1 Arabidopsis thaliana 107-113 33601051-3 2021 We report here that a cyclic nucleotide-gated channel (CNGC) protein, CNGC15, and the nitrate transceptor (NRT1.1) constitute a molecular switch that controls calcium influx depending on nitrate levels. Nitrates 187-194 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 70-76 33601051-3 2021 We report here that a cyclic nucleotide-gated channel (CNGC) protein, CNGC15, and the nitrate transceptor (NRT1.1) constitute a molecular switch that controls calcium influx depending on nitrate levels. Nitrates 187-194 nitrate transporter 1.1 Arabidopsis thaliana 107-113 33872506-1 2021 Electrocatalytic conversion of nitrate (NO3-) into ammonia can not only eliminate harmful pollutant but also provide a green method for a low-temperature ammonia synthesis. Nitrates 31-38 NBL1, DAN family BMP antagonist Homo sapiens 40-43 33927257-1 2021 An increased nitrate (NO3-) concentration in groundwater has been a rising issue on a global scale in recent years. Nitrates 13-20 NBL1, DAN family BMP antagonist Homo sapiens 22-25 33900460-8 2021 Most nitrate variation has been recorded at or near the water table where concentrations have ranged between 3.47 and 5.88 mg NO3-N/L, and annual maxima have occurred in late winter/spring, which coincides with when most nitrate leaching occurs from agricultural land. Nitrates 5-12 NBL1, DAN family BMP antagonist Homo sapiens 126-129 33849366-9 2021 CONCLUSIONS: Water, heat, and excipients" nitrite and nitrate levels are the key players, which should collectively exist, to cause NDMA formation during MET tablets manufacturing. Nitrates 54-61 SAFB like transcription modulator Homo sapiens 154-157 33422844-1 2021 Nitrogen losses from intensive agricultural production may end up as high nitrate (NO3-) concentrations in groundwater, with a long-term impact on groundwater quality. Nitrates 74-81 NBL1, DAN family BMP antagonist Homo sapiens 83-86 33601051-8 2021 The dynamic interactions between CNGC15 and NRT1.1 therefore controlled the channel activity and Ca2+-influx in a nitrate-dependent manner. Nitrates 114-121 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 33-39 33601051-8 2021 The dynamic interactions between CNGC15 and NRT1.1 therefore controlled the channel activity and Ca2+-influx in a nitrate-dependent manner. Nitrates 114-121 nitrate transporter 1.1 Arabidopsis thaliana 44-50 33579566-4 2021 Batch tests demonstrated that efficient PD with nitrate-to-nitrite transformation ratio of 97.67% supplying stable nitrite for anammox, and phosphorus was mainly removed using nitrate as electron acceptor via DPR with the ideal phosphorus release/uptake rate (7.73/22.17 mgP/gVSS/h). Nitrates 176-183 matrix Gla protein Homo sapiens 271-274 33460896-7 2021 Metagenomics analysis revealed that the preferred metabolic pathway of nitrogen was from ammonium to glutamate via glutamine, and the enzymes governing this transformation were glutamine synthetase and glutamate synthetase; while in nitrate based amendment, the conversion from nitrite to ammonium was restrained by the low abundance of nitrite reductase enzyme and therefore retarded the TPH degradation rate. Nitrates 233-240 glutamate-ammonia ligase Homo sapiens 177-197 33949893-8 2021 RESULTS: Spontaneous preterm birth at 20-31 wk was increased in association with tap water nitrate concentrations during pregnancy of 5 to <10mg/L [odds ratio (OR)=1.47; 95% confidence interval (CI): 1.29, 1.67] and >=10mg/L (OR=2.52; 95% CI: 1.49, 4.26) compared with <5mg/L (as nitrogen). Nitrates 91-98 nuclear RNA export factor 1 Homo sapiens 81-84 33949893-12 2021 Notably, we estimated modestly increased odds associated with tap water nitrate concentrations of 5 to <10mg/L (below the federal drinking water standard of 10mg/L) relative to <5mg/L. Nitrates 72-79 nuclear RNA export factor 1 Homo sapiens 62-65 33934458-5 2021 The Diatom/Dino trend is explained by an altered nutrient composition caused by a decadal increase in anthropogenic input, where nitrate increased rapidly while ammonium and phosphate were relatively constant. Nitrates 129-136 damage induced long noncoding RNA Homo sapiens 11-15 33934458-7 2021 Our models predict that the Diatom/Dino ratio will further increase with increasing anthropogenic input and global warming in subtropical estuarine ecosystems with nitrate as the dominant inorganic nitrogen; its ecological consequences are worthy of further investigation. Nitrates 164-171 damage induced long noncoding RNA Homo sapiens 35-39 33624251-2 2021 The GATA transcription factors belonging to type IV zinc-finger proteins, play a significant role in regulating light morphogenesis, nitrate assimilation, and organ development in plants. Nitrates 133-140 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 4-8 33210841-0 2021 HBI1-TCP20 interaction positively regulates the CEPs-mediated systemic nitrate acquisition. Nitrates 71-78 chaperonin containing TCP1 subunit 6A Homo sapiens 5-10 33210841-4 2021 Here, we demonstrate that the transcription factors HBI1 and TCP20 play important roles in plant growth and development in response to fluctuating nitrate supply. Nitrates 147-154 chaperonin containing TCP1 subunit 6A Homo sapiens 61-66 33210841-5 2021 HBI1 physically interacts with TCP20, and this interaction was enhanced by the nitrate starvation. Nitrates 79-86 chaperonin containing TCP1 subunit 6A Homo sapiens 31-36 33210841-7 2021 Mutation in HBIs and/or TCP20 resulted in impaired systemic nitrate acquisition response. Nitrates 60-67 chaperonin containing TCP1 subunit 6A Homo sapiens 24-29 33210841-8 2021 Our solid genetic and molecular evidences strongly indicate that the HBI1-TCP20 module positively regulates the CEPs-mediated systemic nitrate acquisition. Nitrates 135-142 chaperonin containing TCP1 subunit 6A Homo sapiens 74-79 33713800-3 2021 We showed that at conditions of increased NO need, this nitrate reservoir is used in situ to generate nitrite and NO, at least in part via the nitrate reductase activity of xanthine oxidoreductase (XOR). Nitrates 56-63 xanthine dehydrogenase Rattus norvegicus 173-196 33713800-3 2021 We showed that at conditions of increased NO need, this nitrate reservoir is used in situ to generate nitrite and NO, at least in part via the nitrate reductase activity of xanthine oxidoreductase (XOR). Nitrates 56-63 xanthine dehydrogenase Rattus norvegicus 198-201 33713800-8 2021 During the course of the overall experiment there was a gradual increase of XOR expression in muscle tissue, which likely led to enhanced nitrate to nitrite reduction. Nitrates 138-145 xanthine dehydrogenase Rattus norvegicus 76-79 33947005-1 2021 Beneficial metabolic effects of inorganic nitrate (NO3-) and nitrite (NO2-) in type 2 diabetes mellitus (T2DM) have been documented in animal experiments; however, this is not the case for humans. Nitrates 42-49 NBL1, DAN family BMP antagonist Homo sapiens 51-54 33886581-5 2021 In contrast, in Pkd1RC/RC mice, sodium nitrate supplementation increased serum nitrate/nitrite levels by ~25-fold in the high dose group (P<0.001), but kidney enlargement and percentage cyst area was not altered, regardless of dose. Nitrates 39-46 polycystin 1, transient receptor potential channel interacting Mus musculus 16-22 33601051-4 2021 CNGC15 gene expression was induced by nitrate and the CNGC15 protein was localized to the plasma membrane after establishment of young seedlings. Nitrates 38-45 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 0-6 33601051-5 2021 Disruption of CNGC15 gene resulted in the loss of nitrate-induced Ca2+ signature (primary nitrate responses) and retarded root growth, reminiscent to the phenotype observed in the nrt1.1 mutant. Nitrates 50-57 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 14-20 33601051-5 2021 Disruption of CNGC15 gene resulted in the loss of nitrate-induced Ca2+ signature (primary nitrate responses) and retarded root growth, reminiscent to the phenotype observed in the nrt1.1 mutant. Nitrates 90-97 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 14-20 33601051-7 2021 Importantly, CNGC15-NRT1.1 interaction silenced the channel activity of the heterocomplex that dissociated upon the rise in nitrate levels leading to re-activation of the CNGC15 channel. Nitrates 124-131 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 13-19 33601051-7 2021 Importantly, CNGC15-NRT1.1 interaction silenced the channel activity of the heterocomplex that dissociated upon the rise in nitrate levels leading to re-activation of the CNGC15 channel. Nitrates 124-131 nitrate transporter 1.1 Arabidopsis thaliana 20-26 33601051-7 2021 Importantly, CNGC15-NRT1.1 interaction silenced the channel activity of the heterocomplex that dissociated upon the rise in nitrate levels leading to re-activation of the CNGC15 channel. Nitrates 124-131 cyclic nucleotide-gated channel 15 Arabidopsis thaliana 171-177 33787201-4 2021 The platinum salt undergoes a vivid change in color and luminescence upon exposure to aqueous NO3- anions at pH <= 0 caused by substitution of the PF6- anions by aqueous NO3-. Nitrates 94-98 sperm associated antigen 17 Homo sapiens 147-150 33851500-2 2021 The cytochrome P450 TxtE nitrates the indole 4-position of L-tryptophan at room temperature using NO, O 2 and NADPH, and has potential to be developed into a useful aromatic nitration biocatalyst. Nitrates 25-33 2,4-dienoyl-CoA reductase 1 Homo sapiens 110-115 33924662-2 2021 The efficiency of Pb(II) removal from aqueous nitrate solutions was considered as a function of the composition of membrane (effect of polymer, plasticizer, and carrier), feed (effect of initial metal concentration and presence of other metal ions) and stripping phases, and temperature of the process conducting. Nitrates 46-53 submaxillary gland androgen regulated protein 3B Homo sapiens 18-24 33840873-4 2021 By comparing chemical constituents between clean and polluted episodes, we find that the elevated PM1 mass concentration during pollution events should be largely attributable to significant increases in organic matter (OM) and inorganic aerosols like sulfate, nitrate, and ammonium (SNA), indicative of the critical role of primary emissions and secondary aerosols in elevating PM1 pollution levels. Nitrates 261-268 transmembrane protein 11 Homo sapiens 98-101 33826745-0 2021 Different DNA-binding specificities of NLP and NIN transcription factors underlie nitrate-induced control of root nodulation. Nitrates 82-89 nin Lotus japonicus 47-50 33826745-3 2021 Although legume NODULE INCEPTION (NIN)-LIKE PROTEIN (NLP) transcription factors have recently been identified, understanding how nodulation is controlled by nitrate, a fundamental question for nitrate-mediated transcriptional regulation of symbiotic genes, remains elusive. Nitrates 157-164 nin Lotus japonicus 16-32 33826745-3 2021 Although legume NODULE INCEPTION (NIN)-LIKE PROTEIN (NLP) transcription factors have recently been identified, understanding how nodulation is controlled by nitrate, a fundamental question for nitrate-mediated transcriptional regulation of symbiotic genes, remains elusive. Nitrates 157-164 nin Lotus japonicus 34-37 33826745-3 2021 Although legume NODULE INCEPTION (NIN)-LIKE PROTEIN (NLP) transcription factors have recently been identified, understanding how nodulation is controlled by nitrate, a fundamental question for nitrate-mediated transcriptional regulation of symbiotic genes, remains elusive. Nitrates 193-200 nin Lotus japonicus 16-32 33826745-3 2021 Although legume NODULE INCEPTION (NIN)-LIKE PROTEIN (NLP) transcription factors have recently been identified, understanding how nodulation is controlled by nitrate, a fundamental question for nitrate-mediated transcriptional regulation of symbiotic genes, remains elusive. Nitrates 193-200 nin Lotus japonicus 34-37 33826745-4 2021 Here, we show that two Lotus japonicus NLPs, NITRATE UNRESPONSIVE SYMBIOSIS 1 (NRSYM1)/LjNLP4 and NRSYM2/LjNLP1, have overlapping functions in the nitrate-induced control of nodulation and act as master regulators for nitrate-dependent gene expression. Nitrates 45-52 NLP1 Lotus japonicus 105-111 33826745-4 2021 Here, we show that two Lotus japonicus NLPs, NITRATE UNRESPONSIVE SYMBIOSIS 1 (NRSYM1)/LjNLP4 and NRSYM2/LjNLP1, have overlapping functions in the nitrate-induced control of nodulation and act as master regulators for nitrate-dependent gene expression. Nitrates 147-154 NLP1 Lotus japonicus 105-111 33826745-4 2021 Here, we show that two Lotus japonicus NLPs, NITRATE UNRESPONSIVE SYMBIOSIS 1 (NRSYM1)/LjNLP4 and NRSYM2/LjNLP1, have overlapping functions in the nitrate-induced control of nodulation and act as master regulators for nitrate-dependent gene expression. Nitrates 218-225 NLP1 Lotus japonicus 105-111 33515769-0 2021 CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Nitrates 95-102 cleavage and polyadenylation specificity factor 30 Arabidopsis thaliana 0-6 33515769-7 2021 Wild-type CPSF30-L rescued defects in APA and nitrate metabolism, but m6A-binding defective mutants did not. Nitrates 46-53 cleavage and polyadenylation specificity factor 30 Arabidopsis thaliana 10-16 33515769-8 2021 Taken together, our results demonstrated that m6A modification regulates APA in Arabidopsis, and revealed that m6A reader CPSF30-L affects nitrate signaling by controlling APA. Nitrates 139-146 cleavage and polyadenylation specificity factor 30 Arabidopsis thaliana 122-128 33393351-5 2021 Extrapolation of the experimental data resulted in values for all the nitrate-bands of the afreea i.e. fully hydrated NO3-(aq). Nitrates 70-77 NBL1, DAN family BMP antagonist Homo sapiens 118-121 33450066-3 2021 Whereas ALDH2 is known to directly activate organic nitrates in vessels, the contribution of vascular CYPs is unknown and was studied here. Nitrates 52-60 aldehyde dehydrogenase 2, mitochondrial Mus musculus 8-13 33168291-0 2021 A novel strategy for sequential reduction of nitrate into nitrogen by CO2 anion radical: Experimental study and DFT calculation. Nitrates 45-52 complement C2 Homo sapiens 70-73 33168291-1 2021 In order to expand the application of CO2 anion radical (CO2-), as a novel green reductant in the control of environmental pollution, CO2- radical was induced into the reduction of nitrate. Nitrates 181-188 complement C2 Homo sapiens 38-41 33168291-1 2021 In order to expand the application of CO2 anion radical (CO2-), as a novel green reductant in the control of environmental pollution, CO2- radical was induced into the reduction of nitrate. Nitrates 181-188 complement C2 Homo sapiens 57-60 33168291-1 2021 In order to expand the application of CO2 anion radical (CO2-), as a novel green reductant in the control of environmental pollution, CO2- radical was induced into the reduction of nitrate. Nitrates 181-188 complement C2 Homo sapiens 57-60 33168291-2 2021 The reduction efficiency, products and mechanism of nitrate or nitrite by CO2- radical were investigated based on the results of batch experiments and theoretical calculation using density functional theory (DFT) methods, respectively. Nitrates 52-59 complement C2 Homo sapiens 74-77 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 41-48 complement C2 Homo sapiens 62-65 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 41-48 complement C2 Homo sapiens 221-224 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 62-65 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 221-224 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 62-65 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 221-224 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 62-65 33168291-3 2021 It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2). Nitrates 200-207 complement C2 Homo sapiens 221-224 33168291-4 2021 On this basis, a novel strategy of rapid reduction of nitrate into N2 using CO2- radical was proposed. Nitrates 54-61 complement C2 Homo sapiens 76-79 33168291-5 2021 Specifically, nitrate was firstly reduced into nitrite with the assistance of Zn/Ag bimetal, and then nitrite was further reduced into N2 by CO2- radical. Nitrates 14-21 complement C2 Homo sapiens 141-144 33168291-7 2021 This work provided a promising approach for the reduction of nitrate into nitrogen with high efficiency and high N2 selectivity by CO2- radical. Nitrates 61-68 complement C2 Homo sapiens 131-134 33115598-1 2021 BACKGROUND: Vitamin C may enhance nitric oxide (NO) production through stepwise reduction of dietary nitrate (NO3) to nitrite (NO2) to NO. Nitrates 101-108 NBL1, DAN family BMP antagonist Homo sapiens 110-113 33264477-1 2021 Diatoms are among the few eukaryotes known to store nitrate (NO3 - ) and to use it as an electron acceptor for respiration in the absence of light and O2 . Nitrates 52-59 NBL1, DAN family BMP antagonist Homo sapiens 61-64 33090485-0 2021 Involvement of boron transporter BOR1 in growth under low-boron and high-nitrate conditions in Arabidopsis thaliana. Nitrates 73-80 HCO3- transporter family Arabidopsis thaliana 33-37 33090485-2 2021 It has been reported that nitrate (NO3 - ) concentrations significantly influence B concentrations in leaves and BOR1 mRNA accumulation in roots. Nitrates 26-33 HCO3- transporter family Arabidopsis thaliana 113-117 33127147-12 2021 Vertically increased NO3 radicals may imply the formation of nitrate aerosols and further increase the nitrate content in high- altitude particulate matter. Nitrates 61-68 NBL1, DAN family BMP antagonist Homo sapiens 21-24 33127147-12 2021 Vertically increased NO3 radicals may imply the formation of nitrate aerosols and further increase the nitrate content in high- altitude particulate matter. Nitrates 103-110 NBL1, DAN family BMP antagonist Homo sapiens 21-24 33868355-0 2021 Regulation of Lateral Root Development by Shoot-Sensed Far-Red Light via HY5 Is Nitrate-Dependent and Involves the NRT2.1 Nitrate Transporter. Nitrates 80-87 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 73-76 33868355-9 2021 Consistently, a loss-of-function mutant of a nitrate transporter gene NRT2.1 lacked low R:FR-induced lateral root reduction and its root growth was hypersensitive to low nitrate. Nitrates 45-52 nitrate transporter 2:1 Arabidopsis thaliana 70-74 33868355-10 2021 ELONGATED HYPOCOTYL5 (HY5) plays an important role in the root response to low R:FR and we found that it was less sensitive to low nitrate conditions with regards to lateral root growth. Nitrates 131-138 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 10-20 33868355-10 2021 ELONGATED HYPOCOTYL5 (HY5) plays an important role in the root response to low R:FR and we found that it was less sensitive to low nitrate conditions with regards to lateral root growth. Nitrates 131-138 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 22-25 33868355-11 2021 In addition, we found that low R:FR increases NRT2.1 expression and that low nitrate enhances HY5 expression. Nitrates 77-84 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 94-97 33868355-14 2021 Together our results show that nitrate signaling can repress low R:FR responses and that this involves signaling via HY5 and NRT2.1. Nitrates 31-38 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 117-120 33868355-14 2021 Together our results show that nitrate signaling can repress low R:FR responses and that this involves signaling via HY5 and NRT2.1. Nitrates 31-38 nitrate transporter 2:1 Arabidopsis thaliana 125-129 33785324-12 2021 CONCLUSION: These findings support the hypothesis that drinking high nitrate water increases oral nitrate-reducing bacteria, which likely results in increased NOC. Nitrates 69-76 nocturnin Homo sapiens 159-162 33785324-12 2021 CONCLUSION: These findings support the hypothesis that drinking high nitrate water increases oral nitrate-reducing bacteria, which likely results in increased NOC. Nitrates 98-105 nocturnin Homo sapiens 159-162 33838420-6 2021 Results revealed that pinewood-derived biochar had its maximum performance at pH 2, with predicted equilibrium uptakes of 20.5 and 4.20 mg/g for phosphate and nitrate, respectively at initial solute concentrations of 60 mg/L within 360 min. Nitrates 159-166 phenylalanine hydroxylase Homo sapiens 78-80 33598673-3 2021 The mononitrate species formed is then further reacted with TMS2Pz to doubly deoxygenate nitrate and form [(L-)Ni(NO)]2, dimeric via bridging pyrazolate with bent nitrosyl ligands, representing a two-electron reduction of coordinated nitrate. Nitrates 8-15 serine incorporator 1 Homo sapiens 60-64 33796477-6 2021 Our results revealed that CD18low mice infected with Pb18 survived during the time analyzed; their lungs showed fewer granulomas, a lower fungal load, lower levels of nitrate, and production of high levels of IgG1 in comparison to WT animals. Nitrates 167-174 integrin beta 2 Mus musculus 26-30 33187786-13 2021 Overall, the results suggest that EVOH-g-DMAC NFM is efficient, low-cost (13 USD/m3) and recyclable material for sustainable removal of nitrate from dairy manure wastewater without requiring any ionic strength or pH adjustment. Nitrates 136-143 neurofilament medium chain Homo sapiens 46-49 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Nitrates 95-102 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 14-18 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Nitrates 95-102 Raffinose synthase family protein Arabidopsis thaliana 23-28 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Nitrates 202-209 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 14-18 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Nitrates 202-209 Raffinose synthase family protein Arabidopsis thaliana 23-28 33333400-7 2021 The results of nitrate isotopes indicated that NO3- mainly originated from soil N nitrogen, chemical fertilizer, and manure and sewage wastes. Nitrates 15-22 NBL1, DAN family BMP antagonist Homo sapiens 47-50 33687628-3 2021 Nitrate reduction resulted in the production of nitrogen gas, while sulfate formed due to sulfide oxidation. Nitrates 0-7 gastrin Homo sapiens 57-60 32130090-1 2021 The aim of this study was to determine the effect of five days dietary nitrate (NO3-) consumption on exercise tolerance and thermoregulation during cycling in hot, dry conditions. Nitrates 71-78 NBL1, DAN family BMP antagonist Homo sapiens 80-83 33284304-11 2021 Compared with the low humidity period, both PM1 and PM2.5 show higher mass fraction of secondary inorganic aerosols (SIA, mainly as nitrate, sulfate and ammonium) and secondary organic aerosols (SOA) during high humidity and fog episodes. Nitrates 132-139 transmembrane protein 11 Homo sapiens 44-47 33462996-1 2021 In order to reduce nitrate in vivo, the spore-specific respiratory nitrate reductase, Nar1, of Streptomyces coelicolor relies on an active cytochrome bcc-aa3 oxidase supercomplex (bcc-aa3 supercomplex). Nitrates 19-26 SCO2473 Streptomyces coelicolor A3(2) 67-84 33109332-6 2021 The crystallographic structure of lysozyme with the IL of ethylammonium nitrate present confirmed the loop region was extended, and identified three specific binding sites with nitrate ions, and that the positively charged areas were IL sensitive regions. Nitrates 72-79 lysozyme Homo sapiens 34-42 33331676-0 2021 Abscisic acid signaling negatively regulates nitrate uptake via phosphorylation of NRT1.1 by SnRK2s in Arabidopsis. Nitrates 45-52 nitrate transporter 1.1 Arabidopsis thaliana 83-89 33331676-6 2021 Strikingly, SnRK2.2/2.3/2.6 proteins interacted with and phosphorylated the nitrate transceptor NITRATE TRANSPORTER1.1 (NRT1.1) in vitro and in vivo. Nitrates 76-83 nitrate transporter 1.1 Arabidopsis thaliana 96-118 33331676-6 2021 Strikingly, SnRK2.2/2.3/2.6 proteins interacted with and phosphorylated the nitrate transceptor NITRATE TRANSPORTER1.1 (NRT1.1) in vitro and in vivo. Nitrates 76-83 nitrate transporter 1.1 Arabidopsis thaliana 120-126 33331676-7 2021 The phosphorylation of NRT1.1 by SnRK2s resulted in a significant decrease of nitrate uptake and impairment of root growth. Nitrates 78-85 nitrate transporter 1.1 Arabidopsis thaliana 23-29 33569852-4 2021 Density functional theory (DFT) calculations reproduce experimental results and show that dissociation of nitrate ligands, with ejection of neutral NO2 , is favored for both [UO2 (NO3 )3 ]- and [UO2 (NO3 )2 (O2 )]- . Nitrates 106-113 NBL1, DAN family BMP antagonist Homo sapiens 180-183 33569852-4 2021 Density functional theory (DFT) calculations reproduce experimental results and show that dissociation of nitrate ligands, with ejection of neutral NO2 , is favored for both [UO2 (NO3 )3 ]- and [UO2 (NO3 )2 (O2 )]- . Nitrates 106-113 NBL1, DAN family BMP antagonist Homo sapiens 200-203 33686225-0 2021 A type 2C protein phosphatase activates high-affinity nitrate uptake by dephosphorylating NRT2.1. Nitrates 54-61 nitrate transporter 2:1 Arabidopsis thaliana 90-94 33686225-1 2021 The nitrate transporter NRT2.1, which plays a central role in high-affinity nitrate uptake in roots, is activated at the post-translational level in response to nitrogen (N) starvation1,2. Nitrates 4-11 nitrate transporter 2:1 Arabidopsis thaliana 24-28 33686225-3 2021 Here, we show that a type 2C protein phosphatase, designated CEPD-induced phosphatase (CEPH), activates high-affinity nitrate uptake by directly dephosphorylating Ser501 of NRT2.1, a residue that functions as a negative phospho-switch in Arabidopsis2. Nitrates 118-125 nitrate transporter 2:1 Arabidopsis thaliana 173-179 33686225-6 2021 Collectively, our results identify CEPH as a crucial enzyme in the N-starvation-dependent activation of NRT2.1 and provide molecular and mechanistic insights into how plants regulate high-affinity nitrate uptake at the post-translational level in response to the N environment. Nitrates 197-204 nitrate transporter 2:1 Arabidopsis thaliana 104-110 33637855-2 2021 Here, we show that a genome-wide association study using Arabidopsis thaliana accessions suggested an association between different magnitudes of N deficiency responses and diversity in NRT1.1/NPF6.3 that encodes a dual-affinity nitrate transporter involved in nitrate uptake by roots. Nitrates 229-236 nitrate transporter 1.1 Arabidopsis thaliana 186-192 33637855-2 2021 Here, we show that a genome-wide association study using Arabidopsis thaliana accessions suggested an association between different magnitudes of N deficiency responses and diversity in NRT1.1/NPF6.3 that encodes a dual-affinity nitrate transporter involved in nitrate uptake by roots. Nitrates 229-236 nitrate transporter 1.1 Arabidopsis thaliana 193-199 33637855-2 2021 Here, we show that a genome-wide association study using Arabidopsis thaliana accessions suggested an association between different magnitudes of N deficiency responses and diversity in NRT1.1/NPF6.3 that encodes a dual-affinity nitrate transporter involved in nitrate uptake by roots. Nitrates 261-268 nitrate transporter 1.1 Arabidopsis thaliana 186-192 33637855-2 2021 Here, we show that a genome-wide association study using Arabidopsis thaliana accessions suggested an association between different magnitudes of N deficiency responses and diversity in NRT1.1/NPF6.3 that encodes a dual-affinity nitrate transporter involved in nitrate uptake by roots. Nitrates 261-268 nitrate transporter 1.1 Arabidopsis thaliana 193-199 33257046-1 2021 A novel integrated bio-electrochemical system with sulfur autotrophic denitrification (SAD) and electrocoagulation (BESAD-EC) system was established to remove nitrate (NO3--N) and phosphorus from contaminated groundwater. Nitrates 159-166 NBL1, DAN family BMP antagonist Homo sapiens 168-171 33472361-4 2021 Increasing pH and/or decreasing oxygen promoted the conversion of nitrate (NO3-) into NO2- but suppressed the H2O2 formation, suggesting that there was a transition of radicals from oxidizing species like hydroxyl radicals to reducing species like hydrogen atoms and hydrated electrons. Nitrates 66-73 NBL1, DAN family BMP antagonist Homo sapiens 75-78 33594566-1 2021 AD2 for efficient nitrate reduction without nitrite accumulation. Nitrates 18-25 apolipoprotein E Homo sapiens 0-3 33594566-6 2021 Results showed that strain AD2 removed 98.9% of nitrate-nitrogen (NO3--N) with an initial concentration about 100 mg L-1 in 48 h without nitrite-nitrogen (NO2--N) accumulation. Nitrates 48-55 apolipoprotein E Homo sapiens 27-30 33352382-4 2021 Firstly, an acclimation process was used: nitrate was progressively increased in three cultures set at pH 9, 10, or 11. Nitrates 42-49 phenylalanine hydroxylase Homo sapiens 103-105 33352382-5 2021 This method allowed to observe for the first time nitrate reduction up to pH 10 and 100 mM nitrate with dihydrogen, or up to pH 10 and 400 mM nitrate with acetate. Nitrates 50-57 phenylalanine hydroxylase Homo sapiens 74-76 33352382-5 2021 This method allowed to observe for the first time nitrate reduction up to pH 10 and 100 mM nitrate with dihydrogen, or up to pH 10 and 400 mM nitrate with acetate. Nitrates 91-98 phenylalanine hydroxylase Homo sapiens 74-76 33352382-5 2021 This method allowed to observe for the first time nitrate reduction up to pH 10 and 100 mM nitrate with dihydrogen, or up to pH 10 and 400 mM nitrate with acetate. Nitrates 91-98 phenylalanine hydroxylase Homo sapiens 74-76 33352382-10 2021 Finally, the use of long duration cultures with a highly alkaline pH allowed a nitrate reduction up to pH 11.5 with acetate. Nitrates 79-86 phenylalanine hydroxylase Homo sapiens 66-68 33352382-10 2021 Finally, the use of long duration cultures with a highly alkaline pH allowed a nitrate reduction up to pH 11.5 with acetate. Nitrates 79-86 phenylalanine hydroxylase Homo sapiens 103-105 33352382-12 2021 Instead, bacteria used organic matter from inoculum to reduce nitrate at pH 11.5. Nitrates 62-69 phenylalanine hydroxylase Homo sapiens 73-75 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 1.1 Arabidopsis thaliana 68-91 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 1.1 Arabidopsis thaliana 93-99 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 2:1 Arabidopsis thaliana 105-128 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 2:1 Arabidopsis thaliana 130-134 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 1.1 Arabidopsis thaliana 171-177 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 2:1 Arabidopsis thaliana 130-136 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 nitrate transporter 1.1 Arabidopsis thaliana 192-196 33643357-5 2021 An extended photoperiod also improved the root nitrate uptake of by NITRATE TRANSPORTER 1.1 (NRT1.1) and NITRATE TRANSPORTER 2.1 (NRT2.1), whereas the loss of function of NRT1.1/NRT2.1 in the nrt1.1-1/2.1-2 mutants suppressed the expression of the key flowering genes CONSTANS (CO) and FLOWERING LOCUS T (FT), and reduced the sensitivity of the photoperiodic flowering responses to elevated levels of nitrate. Nitrates 47-54 PEBP (phosphatidylethanolamine-binding protein) family protein Arabidopsis thaliana 286-303 33580260-3 2021 Different from most NRT1 transporters, NRT1.13 does not have the conserved proline residue between transmembrane domains 10 and 11; an essential residue for nitrate transport activity in CHL1/NRT1.1/NPF6.3. Nitrates 157-164 nitrate transporter 1.1 Arabidopsis thaliana 187-191 33580260-3 2021 Different from most NRT1 transporters, NRT1.13 does not have the conserved proline residue between transmembrane domains 10 and 11; an essential residue for nitrate transport activity in CHL1/NRT1.1/NPF6.3. Nitrates 157-164 nitrate transporter 1.1 Arabidopsis thaliana 39-45 33580260-5 2021 However, when Ser 487 at the corresponding position was converted back to proline, NRT1.13 S487P regained nitrate uptake activity, suggesting that wild-type NRT1.13 cannot transport nitrate but can bind it. Nitrates 106-113 nitrate transporter 1.1 Arabidopsis thaliana 83-87 33580260-5 2021 However, when Ser 487 at the corresponding position was converted back to proline, NRT1.13 S487P regained nitrate uptake activity, suggesting that wild-type NRT1.13 cannot transport nitrate but can bind it. Nitrates 182-189 nitrate transporter 1.1 Arabidopsis thaliana 83-87 33560419-0 2021 Kinase SnRK1.1 Regulates nitrate channel SLAH3 Engaged in Nitrate-Dependent Alleviation of Ammonium Toxicity. Nitrates 25-32 SNF1 kinase homolog 10 Arabidopsis thaliana 7-14 33560419-0 2021 Kinase SnRK1.1 Regulates nitrate channel SLAH3 Engaged in Nitrate-Dependent Alleviation of Ammonium Toxicity. Nitrates 25-32 SLAC1 homologue 3 Arabidopsis thaliana 41-46 33560419-0 2021 Kinase SnRK1.1 Regulates nitrate channel SLAH3 Engaged in Nitrate-Dependent Alleviation of Ammonium Toxicity. Nitrates 58-65 SNF1 kinase homolog 10 Arabidopsis thaliana 7-14 33560419-0 2021 Kinase SnRK1.1 Regulates nitrate channel SLAH3 Engaged in Nitrate-Dependent Alleviation of Ammonium Toxicity. Nitrates 58-65 SLAC1 homologue 3 Arabidopsis thaliana 41-46 33560419-2 2021 Small amounts of NO3- can significantly mitigate ammonium toxicity, and the anion channel SLAC1 homologue 3 (SLAH3) is involved in this process, but the mechanistic detail of how SLAH3 regulates nitrate-dependent alleviation of ammonium toxicity is still largely unknown. Nitrates 195-202 SLAC1 homologue 3 Arabidopsis thaliana 90-107 33560419-2 2021 Small amounts of NO3- can significantly mitigate ammonium toxicity, and the anion channel SLAC1 homologue 3 (SLAH3) is involved in this process, but the mechanistic detail of how SLAH3 regulates nitrate-dependent alleviation of ammonium toxicity is still largely unknown. Nitrates 195-202 SLAC1 homologue 3 Arabidopsis thaliana 179-184 33560419-9 2021 Our study reveals that the C-terminal phosphorylation also plays important role in SLAH3 regulation and provides additional insights into nitrate-dependent alleviation of ammonium toxicity in plants. Nitrates 138-145 SLAC1 homologue 3 Arabidopsis thaliana 83-88 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 90-97 nitrate transporter 2:1 Arabidopsis thaliana 135-139 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 90-97 nitrate transporter 2:1 Arabidopsis thaliana 166-172 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 90-97 nitrate transporter 2.2 Arabidopsis thaliana 174-180 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 90-97 nitrate transporter 2:1 Arabidopsis thaliana 166-170 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 90-97 nitrate transporter 2:1 Arabidopsis thaliana 166-170 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 99-103 nitrate transporter 2:1 Arabidopsis thaliana 135-139 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 99-103 nitrate transporter 2:1 Arabidopsis thaliana 166-172 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 99-103 nitrate transporter 2.2 Arabidopsis thaliana 174-180 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 99-103 nitrate transporter 2:1 Arabidopsis thaliana 166-170 33582801-1 2021 In Arabidopsis (Arabidopsis thaliana), the High-Affinity Transport System (HATS) for root nitrate (NO3-) uptake depends mainly on four NRT2 NO3- transporters, namely NRT2.1, NRT2.2, NRT2.4, and NRT2.5. Nitrates 99-103 nitrate transporter 2:1 Arabidopsis thaliana 166-170 33398446-4 2021 We showed that the removal of nitrate in P. aeruginosa PAO1 was repressed by both the las and rhl systems. Nitrates 30-37 ATP-dependent RNA helicase RhlB Pseudomonas aeruginosa PAO1 94-97 33399250-6 2021 This coordination is achieved by nitrate-dependent dephosphorylation of the PIN2 auxin efflux carrier at a previously uncharacterized phosphorylation site, leading to subsequent PIN2 lateralization and thereby regulating auxin flow between adjacent tissues. Nitrates 33-40 telomeric repeat binding factor 1 Homo sapiens 76-80 33399250-6 2021 This coordination is achieved by nitrate-dependent dephosphorylation of the PIN2 auxin efflux carrier at a previously uncharacterized phosphorylation site, leading to subsequent PIN2 lateralization and thereby regulating auxin flow between adjacent tissues. Nitrates 33-40 telomeric repeat binding factor 1 Homo sapiens 178-182 33170463-9 2021 The bivariate plots of NO3 with other ions suggested that the principal origin of nitrate in this study is related to the excess application of fertilizers and sewages. Nitrates 82-89 NBL1, DAN family BMP antagonist Homo sapiens 23-26 32026170-7 2021 The groundwater quality of the Bathinda district is a matter of concern due to elevated levels of alkalinity, hardness, fluoride, uranium and nitrate (NO3-). Nitrates 142-149 NBL1, DAN family BMP antagonist Homo sapiens 151-154 33487355-5 2021 In conclusion, NLP7 binds to the TAR2 promoter and activates TAR2 expression, thereby promoting nitrate-dependent LR development. Nitrates 96-103 trace amine associated receptor 2 Homo sapiens 33-37 33539179-1 2021 BACKGROUND: High levels of nitrate (NO3-) in drinking water cause methemoglobinemia in infants; however, few studies have examined the potential effects of low-level exposure on fetal growth, and the results have been inconsistent. Nitrates 27-34 NBL1, DAN family BMP antagonist Homo sapiens 36-39 32767561-1 2021 BACKGROUND: 3,4-dimethylpyrazole phosphate (DMPP) is a nitrification inhibitor which can restrict nitrate (NO3 - ) production. Nitrates 98-105 NBL1, DAN family BMP antagonist Homo sapiens 107-110 33487355-5 2021 In conclusion, NLP7 binds to the TAR2 promoter and activates TAR2 expression, thereby promoting nitrate-dependent LR development. Nitrates 96-103 trace amine associated receptor 2 Homo sapiens 61-65 33047410-4 2021 The delta15 N values are often lower in soil nitrate (NO3 - ) than in ammonium (NH4 + ) due to large isotopic fractionation during nitrification. Nitrates 45-52 NBL1, DAN family BMP antagonist Homo sapiens 54-57 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 uncoupling protein 1 Rattus norvegicus 105-125 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 uncoupling protein 1 Rattus norvegicus 127-131 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 peroxisome proliferator-activated receptor gamma Rattus norvegicus 134-182 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 peroxisome proliferator-activated receptor gamma Rattus norvegicus 184-194 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 PPARG coactivator 1 alpha Rattus norvegicus 201-231 32950634-2 2021 This study aims at determining effects of long-term nitrate administration on protein and mRNA levels of uncoupling protein 1 (UCP1), peroxisome proliferator activated receptor gamma (PPAR-gamma), and PPAR-gamma coactivator 1 alpha (PGC1-alpha) in epididymal adipose tissue (eAT) of rats with T2D. Nitrates 52-59 PPARG coactivator 1 alpha Rattus norvegicus 233-243 32840941-1 2021 RATIONALE: This study aims to develop a simplified denitrifier method for the delta15 N and delta18 O analysis of nitrate (NO3 - ) in natural water samples combining the method of Zhu et al [14] and the original denitrifier method of Sigman et al [12] . Nitrates 114-121 NBL1, DAN family BMP antagonist Homo sapiens 123-126 33367322-2 2021 In 1-3, the nearly planar molecular structures consisting of two DyIII ions and two L ligands are almost perpendicular to four nitrate ligands, which provides an opportunity to introduce auxiliary ligands (H2O or TPO) at the terminal position along the DyDy orientation of [Dy2]. Nitrates 127-134 thyroid peroxidase Homo sapiens 213-216 33432967-8 2021 While MET treatment reduced myocardial nitrates, only MET treatment completely restored microvessel dilation to dobutamine stimulation in the absence of NO and prostanoids (combined inhibition), indicating that MET restored the coronary flow reserve attributable to endothelium-derived hyperpolarisation. Nitrates 39-47 MET proto-oncogene, receptor tyrosine kinase Rattus norvegicus 6-9 32862077-2 2021 By analyzing the spectral absorption characteristics of nitrate, COD, and turbidity standard solutions and the mixtures of them, the absorption spectra in the range of 225-260 nm, 260-320 nm and 320-700 nm were selected as the characteristic spectra of nitrate, COD and turbidity, respectively. Nitrates 253-260 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 262-265 33297218-8 2021 In contrast, PAH degradation has been reported to increase up to 54% when nitrate is used as electron acceptor in low-temperature biochar-amended sediments. Nitrates 74-81 phenylalanine hydroxylase Homo sapiens 13-16 33128338-0 2021 S-Nitrosylation of Akt by organic nitrate delays revascularization and the recovery of cardiac function in mice following myocardial infarction. Nitrates 34-41 thymoma viral proto-oncogene 1 Mus musculus 19-22 33128338-8 2021 In conclusion, long-term usage of organic nitrate may inactivate Akt to delay ischaemia-induced revascularization and the recovery of cardiac function through NO-mediated S-Nitrosylation. Nitrates 42-49 thymoma viral proto-oncogene 1 Mus musculus 65-68 33080433-10 2021 The resulting SECs for Kali river basin are: 2.03 (agricultural), 1.44 (fallow), and 0.92 (settlement) for monsoonal nitrate; while for non-monsoonal nitrate, SECs are 0.51 (agricultural), 0.23 (fallow), and 0.10 (settlement). Nitrates 117-124 SLAM family member 6 Homo sapiens 23-27 33080433-10 2021 The resulting SECs for Kali river basin are: 2.03 (agricultural), 1.44 (fallow), and 0.92 (settlement) for monsoonal nitrate; while for non-monsoonal nitrate, SECs are 0.51 (agricultural), 0.23 (fallow), and 0.10 (settlement). Nitrates 150-157 SLAM family member 6 Homo sapiens 23-27 33206969-6 2020 By constructing a mutant strain defective for napA, we demonstrated that the reduction of nitrate to nitrite was catalyzed by the periplasmic nitrate reductase, NapA. Nitrates 90-97 periplasmic nitrate reductase subunit alpha Agrobacterium fabrum str. C58 46-50 33270921-1 2021 Denitrifying woodchip bioreactors (DWBs) are potential low-cost technologies for the removal of nitrate (NO3 - ) in water through denitrification. Nitrates 96-103 NBL1, DAN family BMP antagonist Homo sapiens 105-108 33206969-6 2020 By constructing a mutant strain defective for napA, we demonstrated that the reduction of nitrate to nitrite was catalyzed by the periplasmic nitrate reductase, NapA. Nitrates 90-97 periplasmic nitrate reductase subunit alpha Agrobacterium fabrum str. C58 161-165 33374906-7 2020 Nitrate assimilation led to excessive ammonium accumulation in the shoot and lower nitrogen uptake, which exacerbated growth retardation of vha-a2 vha-a3. Nitrates 0-7 vacuolar proton ATPase A2 Arabidopsis thaliana 140-146 33367898-4 2021 In Arabidopsis, the CIPK23 kinase has emerged as a major hub driving root responses to diverse environmental stresses including drought, salinity and nutrient imbalances such as potassium, nitrate and iron deficiencies as well as ammonium, magnesium and non-iron metals toxicities. Nitrates 189-196 CBL-interacting protein kinase 23 Arabidopsis thaliana 20-26 33374906-7 2020 Nitrate assimilation led to excessive ammonium accumulation in the shoot and lower nitrogen uptake, which exacerbated growth retardation of vha-a2 vha-a3. Nitrates 0-7 vacuolar proton ATPase A3 Arabidopsis thaliana 147-153 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 89-96 L1 cell adhesion molecule Homo sapiens 81-84 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 89-96 L1 cell adhesion molecule Homo sapiens 81-84 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 89-96 L1 cell adhesion molecule Homo sapiens 81-84 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 178-185 L1 cell adhesion molecule Homo sapiens 50-53 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 178-185 L1 cell adhesion molecule Homo sapiens 81-84 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 178-185 L1 cell adhesion molecule Homo sapiens 81-84 32854085-6 2020 Good linearity (R2 > 0.99) ranges of 0.05 to 5 mg L-1 for nitrite and 1 to 50 mg L-1 for nitrate were obtained and detection limits of 50 mug L-1 for nitrite and 0.32 mg L-1 for nitrate were achieved. Nitrates 178-185 L1 cell adhesion molecule Homo sapiens 81-84 33254675-6 2020 Isotope and NO3-/Cl- analysis indicated that nitrate in the subsidence area water (SAW) was mainly derived from chemical fertilizer (NF) and soil organic nitrogen (NS), while nitrate in the mainstream of the Huihe River water (HRW) was mainly derived from manure/sewage (MS). Nitrates 45-52 NBL1, DAN family BMP antagonist Homo sapiens 12-15 33183558-0 2020 Effect of a plant-based bioequivalent inorganic nitrate (NO3-) complex with vitamins, antioxidants and phytophenol rich food extracts in hypertensive individuals - A randomized, double-blind, placebo-controlled study. Nitrates 48-55 NBL1, DAN family BMP antagonist Homo sapiens 57-60 33183558-1 2020 BACKGROUND: This study assessed efficacy of plant based bioequivalent nitrate complex, consist of vitamins, natural antioxidants and phytophenol rich food extracts to elevate nitric oxide (NO) bioavailability as determined by saliva conversion of nitrate (NO3-) to nitrite (NO2-) a required step to produce NO, in relationship to lowering blood pressure (BP) in both men and women. Nitrates 70-77 NBL1, DAN family BMP antagonist Homo sapiens 256-259 33048402-0 2020 NITROGEN RESPONSE DEFICIENCY 1 - mediated CHL1 induction contributes to optimized growth performance during altered nitrate availability in Arabidopsis. Nitrates 116-123 nitrate transporter 1.1 Arabidopsis thaliana 42-46 33048402-8 2020 We suggest that NID1 plays a crucial role as a transcription factor in optimizing plant growth by modulating the transcript abundance of the nitrate transceptor CHL1, leading to enhanced ABA accumulation in low-nitrate conditions. Nitrates 141-148 nitrate transporter 1.1 Arabidopsis thaliana 161-165 33048402-8 2020 We suggest that NID1 plays a crucial role as a transcription factor in optimizing plant growth by modulating the transcript abundance of the nitrate transceptor CHL1, leading to enhanced ABA accumulation in low-nitrate conditions. Nitrates 211-218 nitrate transporter 1.1 Arabidopsis thaliana 161-165 33169535-1 2020 Metallic Cu is a well-known electrocatalyst for nitrate reduction reaction (NO3 RR), but it suffers from relatively low activity, poor stability, and inducing nitrite accumulation during the long-term operation. Nitrates 48-55 NBL1, DAN family BMP antagonist Homo sapiens 76-79 32933749-1 2020 NRT1.2 has been characterized as a low-affinity nitrate transporter and an abscisic acid (ABA) transporter in Arabidopsis. Nitrates 48-55 nitrate transporter 1:2 Arabidopsis thaliana 0-6 32785584-1 2020 Nitrification is the microbial conversion of reduced forms of nitrogen (N) to nitrate (NO3-), and in fertilized soils it can lead to substantial N losses via NO3- leaching or nitrous oxide (N2O) production. Nitrates 78-85 NBL1, DAN family BMP antagonist Homo sapiens 87-90 33329669-2 2020 Here, we describe the participation of Arabidopsis DNA binding with one finger (DOF) transcription factor CDF3 in nitrate responses and shows that CDF3 gene is induced under nitrate starvation. Nitrates 114-121 cycling DOF factor 3 Arabidopsis thaliana 106-110 33329669-2 2020 Here, we describe the participation of Arabidopsis DNA binding with one finger (DOF) transcription factor CDF3 in nitrate responses and shows that CDF3 gene is induced under nitrate starvation. Nitrates 114-121 cycling DOF factor 3 Arabidopsis thaliana 147-151 33329669-2 2020 Here, we describe the participation of Arabidopsis DNA binding with one finger (DOF) transcription factor CDF3 in nitrate responses and shows that CDF3 gene is induced under nitrate starvation. Nitrates 174-181 cycling DOF factor 3 Arabidopsis thaliana 106-110 33329669-2 2020 Here, we describe the participation of Arabidopsis DNA binding with one finger (DOF) transcription factor CDF3 in nitrate responses and shows that CDF3 gene is induced under nitrate starvation. Nitrates 174-181 cycling DOF factor 3 Arabidopsis thaliana 147-151 33329669-3 2020 Moreover, knockout cdf3 mutant plants exhibit nitrate-dependent lateral and primary root modifications, whereas CDF3 overexpression plants show increased biomass and enhanced root development under both nitrogen poor and rich conditions. Nitrates 46-53 cycling DOF factor 3 Arabidopsis thaliana 19-23 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 cycling DOF factor 3 Arabidopsis thaliana 28-32 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 cycling DOF factor 3 Arabidopsis thaliana 52-56 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 glutamate synthase 2 Arabidopsis thaliana 165-185 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 nitrate transporter 2:1 Arabidopsis thaliana 233-237 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 nitrate transporter 2:1 Arabidopsis thaliana 241-245 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 nitrate transporter 2:1 Arabidopsis thaliana 241-245 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 protein-serine kinase 1 Arabidopsis thaliana 302-305 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Nitrates 105-112 Pyridoxal phosphate phosphatase-related protein Arabidopsis thaliana 310-315 33329669-7 2020 These results highlight CDF3 as an important regulatory factor for the nitrate response, and its potential for improving N use efficiency in crops. Nitrates 71-78 cycling DOF factor 3 Arabidopsis thaliana 24-28 32907713-6 2020 We firstly found that NR activity was roughly positive-correlated with the root auxin level, and there is a crosstalk between nitrate signaling and auxin signaling. Nitrates 126-133 nitrate reductase 1 Arabidopsis thaliana 22-24 33213070-11 2020 The patients that received Vit C had decreased levels of the nitrate and nitrite ratio (p < 0.01) and C-reactive protein levels (p = 0.04). Nitrates 61-68 vitrin Homo sapiens 27-30 32781362-1 2020 Batch experiments were conducted to test the hypothesis that nitrate (NO3-) could be immobilized by biochar via adsorption of CaNO3+ to the negatively charged biochar surfaces. Nitrates 61-68 NBL1, DAN family BMP antagonist Homo sapiens 70-73 33188441-4 2020 Sublingual nitrate may provide additional benefit to rectal NSAIDs in preventing PEP. Nitrates 11-18 prolyl endopeptidase Homo sapiens 81-84 33188441-8 2020 There is emerging data that aggressive hydration with lactated Ringer"s and nitrates may further reduce PEP. Nitrates 76-84 prolyl endopeptidase Homo sapiens 104-107 33047961-4 2020 Deep nitrate storage varied from 43.6 to 1116.3 kg ha-1. Nitrates 5-12 Rho GTPase activating protein 45 Homo sapiens 51-55 32463943-0 2020 NRT2.1 C-terminus phosphorylation prevents root high affinity nitrate uptake activity in Arabidopsis thaliana. Nitrates 62-69 nitrate transporter 2:1 Arabidopsis thaliana 0-6 32463943-1 2020 In Arabidopsis thaliana, NRT2.1 codes for a main component of the root nitrate high-affinity transport system. Nitrates 71-78 nitrate transporter 2:1 Arabidopsis thaliana 25-29 32463943-2 2020 Previous studies revealed that post-translational regulation of NRT2.1 plays an important role in the control of root nitrate uptake and that one mechanism could correspond to NRT2.1 C-terminus processing. Nitrates 118-125 nitrate transporter 2:1 Arabidopsis thaliana 64-70 32463943-2 2020 Previous studies revealed that post-translational regulation of NRT2.1 plays an important role in the control of root nitrate uptake and that one mechanism could correspond to NRT2.1 C-terminus processing. Nitrates 118-125 nitrate transporter 2:1 Arabidopsis thaliana 64-68 32463943-7 2020 Finally, the relative level of serine 501 phosphorylation was found to be increased by ammonium nitrate in wild-type plants, leading to the inactivation of NRT2.1 and to a decrease in high affinity nitrate transport into roots. Nitrates 96-103 nitrate transporter 2:1 Arabidopsis thaliana 156-162 33036562-1 2020 BACKGROUND: High-affinity nitrate transporter 2 (NRT2) genes have been implicated in nitrate absorption and remobilization under nitrogen (N) starvation stress in many plant species, yet little is known about this gene family respond to various stresses often occurs in the production of rapeseed (Brassica napus L.). Nitrates 26-33 nitrate transporter 2:1 Arabidopsis thaliana 49-53 33038483-15 2020 CONCLUSION: Bioactivation of NDOP involves functional XOR, and this new organic nitrate elicits vasorelaxation via NO-cGMP-PKG signaling and activation of KIR channels. Nitrates 80-87 xanthine dehydrogenase Rattus norvegicus 54-57 32870279-0 2020 NRT1.1-centered nitrate signaling in plants. Nitrates 16-23 nitrate transporter 1.1 Arabidopsis thaliana 0-6 32870279-4 2020 NRT1.1 governs a wide range of responses to NO3-, from fast reprogramming of genome expression (the primary nitrate response) to longer-term developmental changes (effects on lateral root development). Nitrates 108-115 nitrate transporter 1.1 Arabidopsis thaliana 0-4 32854899-1 2020 Woodchip bioreactors are a practical, low-cost technology for reducing nitrate (NO3) loads discharged from agriculture. Nitrates 71-78 NBL1, DAN family BMP antagonist Homo sapiens 80-83 32870663-5 2020 Subsequent OH oxidation and direct photolysis both decompose the organic nitrates (ONs, representing bulk functionalities of NACs and organonitrates) in the NO3 -aged wood tar aerosols, thus decreasing the particle absorption. Nitrates 74-82 NBL1, DAN family BMP antagonist Homo sapiens 158-161 32686596-2 2020 We recently demonstrated that nitrate deficiency induces root coiling on horizontal surface through nitrate transporter/sensor NRT1.1 and PIN2- and AUX-mediated polar auxin transport. Nitrates 30-37 telomeric repeat binding factor 1 Homo sapiens 138-142 32686596-3 2020 Here, we show that nitrate deficiency or NRT1.1 loss-of-function induces differential distribution of PIN2 between the future concave and concave sides in root epidermal cells. Nitrates 19-26 telomeric repeat binding factor 1 Homo sapiens 102-106 32146561-6 2020 Nitrate concentrations ranged between 2.43 and 96 mg L-1. Nitrates 0-7 immunoglobulin kappa variable 1-16 Homo sapiens 53-56 32146561-7 2020 Results indicated that nitrate temporal trend was increased significantly in most of the wells, and the spatial trend of area percentage of nitrate class 3 (not permissible limit of more than 50 mg L-1) was positive. Nitrates 140-147 immunoglobulin kappa variable 1-16 Homo sapiens 198-201 33005412-7 2020 Higher concentrations of IL-6, TNF-alpha, IL-1beta, nitrite ( NO 2 - ) and nitrate ( NO 3 - ) and a lower concentration of IL-10 were observed in CD163-deficient mice treated with LPS. Nitrates 76-83 CD163 antigen Mus musculus 148-153 32959807-2 2020 It has been hypothesized that synthesis of oxidized nitrogen in the form of nitrate (NO3-) and nitrite (NO2-), occurred in the prebiotic anoxic Hadean atmosphere. Nitrates 76-83 NBL1, DAN family BMP antagonist Homo sapiens 85-88