PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
16337685-14	2006	PBRs in blood cells appear to play roles in several aspects of the immune response, such as phagocytosis and the secretion of interleukin-2, interleukin-3, and immunoglobulin A (IgA).	pbrs	0-4	interleukin 2	Homo sapiens	126-139
20641889-3	2004	In contrast, PBRs are mitochondrial proteins found in the brain and peripheral tissues (adrenal gland, heart, lung, kidney, and testis) (4); the brain has lower levels of PBR than do the peripheral tissues, and both glial cells and macrophages contain high levels of PBR (5-7).	pbrs	13-17	translocator protein	Rattus norvegicus	171-174
17591555-4	2007	We wished to ascertain whether the observed decrease in in vivo expression of PBRs in the PET scans could be accounted for by a reduction in PBRs per cell by saturation-binding assays of R-PK11195 in cells obtained by bronchoalveolar lavage (BAL).	pbrs	78-82	pyruvate kinase L/R	Homo sapiens	187-191
18557607-3	2008	In biodistribution studies in rats, the distribution of radioactivity of the [ (18)F]PBR compounds paralleled the known localization of PBRs.	pbrs	136-140	translocator protein	Rattus norvegicus	85-88
16337685-14	2006	PBRs in blood cells appear to play roles in several aspects of the immune response, such as phagocytosis and the secretion of interleukin-2, interleukin-3, and immunoglobulin A (IgA).	pbrs	0-4	interleukin 3	Homo sapiens	141-154
14723961-5	2004	The aryloxyanilide derivatives, which have been derived by opening the diazepine ring of 1, are a novel class as PBR ligands and have exhibited high and selective affinity for peripheral benzodiazepine receptors (PBRs).	pbrs	213-217	translocator protein	Rattus norvegicus	113-116
9364456-11	1997	The increase in PBR expression after FNA supports the hypothesis that PBRs can be used as a sensitive marker for CNS injury.	pbrs	70-74	translocator protein	Homo sapiens	16-19
11408831-3	2001	The PBR agonist Ro5-4864 (10 nmol/l to 10 micromol/l) did not affect migration but slightly enhanced phagocytosis, while clonazepam, which binds to the central-type benzodiazepine receptors but has no affinity for PBRs, was ineffective on both parameters up to 10 micromol/l.	pbrs	214-218	translocator protein	Homo sapiens	4-7
10413311-5	1999	In view of the effect of PBR ligands on DNA synthesis, changes in mitochondrial lipid metabolism through interaction with PBRs might lead to biogenesis of mitochondria to support the increased metabolic requirements for cell division, which is even higher in malignant cells.	pbrs	122-126	translocator protein	Homo sapiens	25-28
9171882-3	1997	A PBR ligand-melphalan conjugate (PBR-MEL) was synthesized and evaluated for cytotoxicity and affinity for PBRs.	pbrs	107-111	translocator protein	Rattus norvegicus	2-5
9171882-3	1997	A PBR ligand-melphalan conjugate (PBR-MEL) was synthesized and evaluated for cytotoxicity and affinity for PBRs.	pbrs	107-111	translocator protein	Rattus norvegicus	34-37
8630084-1	1996	In this work, we evaluated the biochemical properties of peripheral benzodiazepine receptors (PBRs) in the porcine endocrine pancreas and their role in insulin release.	pbrs	94-98	insulin	Homo sapiens	152-159
8630084-7	1996	These results show the presence of PBRs in purified porcine pancreatic islets and suggest an implication of PBRs in the mechanisms of insulin release.	pbrs	108-112	insulin	Homo sapiens	134-141
7796139-3	1995	Ro5-4864, a specific agonist of PBRs, also blocked bFGF-induced DNA synthesis.	pbrs	32-36	fibroblast growth factor 2	Rattus norvegicus	51-55
23295386-4	2013	Furthermore, a humanized CYP3A4/3A7 mouse model showed in vivo induction of CYP3A4 mRNA and protein by [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY14,643) in liver but not in intestine, whereas hepatic occupancy of PBRs by PPARalpha was ligand independent.	pbrs	231-235	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	25-31
23295386-4	2013	Furthermore, a humanized CYP3A4/3A7 mouse model showed in vivo induction of CYP3A4 mRNA and protein by [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY14,643) in liver but not in intestine, whereas hepatic occupancy of PBRs by PPARalpha was ligand independent.	pbrs	231-235	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	76-82