PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19918366-6	2009	The transcriptions and expressions of Bax and caspase-3 in group D were increased significantly when compared with groups A, B, and C. In conclusion, DNR-loaded MNPs-Fe3O4 can overcome MDR in vivo.	ferryl iron	166-171	BCL2-associated X protein	Mus musculus	38-41
20352885-5	2010	Results indicated that Fe3O4 nanopaticles adsorbed autovaccine took great advantages over the common alum adjuvants after subcutaneous injection, raised the mass inhibitory rate of tumor, boosted the activity of cytotoxicity and enhanced the level of IFN-gamma cytokine.	ferryl iron	23-28	interferon gamma	Mus musculus	251-260
19942425-0	2010	Facile preparation of magnetic core-shell Fe3O4@Au nanoparticle/myoglobin biofilm for direct electrochemistry.	ferryl iron	42-47	myoglobin	Homo sapiens	64-73
19804631-0	2009	Thermochemotherapy effect of nanosized As2O3/Fe3O4 complex on experimental mouse tumors and its influence on the expression of CD44v6, VEGF-C and MMP-9.	ferryl iron	45-50	vascular endothelial growth factor C	Mus musculus	135-141
19804631-0	2009	Thermochemotherapy effect of nanosized As2O3/Fe3O4 complex on experimental mouse tumors and its influence on the expression of CD44v6, VEGF-C and MMP-9.	ferryl iron	45-50	matrix metallopeptidase 9	Mus musculus	146-151
19804631-8	2009	In addition, thermochemotherapy with the nanosized As2O3/Fe3O4 complex significantly inhibited the expression of CD44v6, VEGF-C, and MMP-9 mRNA (p < 0.05 for each).	ferryl iron	57-62	vascular endothelial growth factor C	Mus musculus	121-127
19804631-8	2009	In addition, thermochemotherapy with the nanosized As2O3/Fe3O4 complex significantly inhibited the expression of CD44v6, VEGF-C, and MMP-9 mRNA (p < 0.05 for each).	ferryl iron	57-62	matrix metallopeptidase 9	Mus musculus	133-138
19804631-9	2009	CONCLUSION: As2O3/Fe3O4 complex combined with MFH had is a promising technique for the minimally invasive elimination of solid tumors and may be have anticancerometastasic effect by inhibiting the expression of CD44v6, VEGF-C, and MMP-9.	ferryl iron	18-23	vascular endothelial growth factor C	Mus musculus	219-225
19804631-9	2009	CONCLUSION: As2O3/Fe3O4 complex combined with MFH had is a promising technique for the minimally invasive elimination of solid tumors and may be have anticancerometastasic effect by inhibiting the expression of CD44v6, VEGF-C, and MMP-9.	ferryl iron	18-23	matrix metallopeptidase 9	Mus musculus	231-236
19708688-2	2009	The active oxidants in P450s have long been assumed to be iron(IV)-oxo porphyrin radical cations termed Compounds I, but P450 Compounds I have proven to be difficult to prepare.	ferryl iron	58-66	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	23-27
19918366-6	2009	The transcriptions and expressions of Bax and caspase-3 in group D were increased significantly when compared with groups A, B, and C. In conclusion, DNR-loaded MNPs-Fe3O4 can overcome MDR in vivo.	ferryl iron	166-171	caspase 3	Mus musculus	46-55
19918367-6	2009	Both BrTet and MNPs-Fe3O4 increased the intracellular DNR accumulation in the K562/A02 cell line, and downregulated the level of mdr1 gene and expression of P-glycoprotein.	ferryl iron	20-25	ATP binding cassette subfamily B member 1	Homo sapiens	129-133
19918367-6	2009	Both BrTet and MNPs-Fe3O4 increased the intracellular DNR accumulation in the K562/A02 cell line, and downregulated the level of mdr1 gene and expression of P-glycoprotein.	ferryl iron	20-25	ATP binding cassette subfamily B member 1	Homo sapiens	157-171
19053409-6	2008	This result demonstrates a successful biomimetic reassembly of [4Fe-4S] cluster [Fe(4)S(4)(SPh)(4)](2-) from NO-modified [Fe-S] clusters, relevant to the repair of DNICs derived from nitrosylation of [4Fe-4S] clusters of endonuclease III back to [4Fe-4S] clusters upon addition of ferrous ion, cysteine, and IscS.	ferryl iron	81-87	surfactant associated 3	Homo sapiens	91-94
19053409-6	2008	This result demonstrates a successful biomimetic reassembly of [4Fe-4S] cluster [Fe(4)S(4)(SPh)(4)](2-) from NO-modified [Fe-S] clusters, relevant to the repair of DNICs derived from nitrosylation of [4Fe-4S] clusters of endonuclease III back to [4Fe-4S] clusters upon addition of ferrous ion, cysteine, and IscS.	ferryl iron	81-87	NFS1 cysteine desulfurase	Homo sapiens	308-312
18500805-0	2008	Ultrasmall c(RGDyK)-coated Fe3O4 nanoparticles and their specific targeting to integrin alpha(v)beta3-rich tumor cells.	ferryl iron	27-32	integrin subunit alpha V	Homo sapiens	79-101
18290338-8	2008	Our study results showed: Fe3O4 particles at a size range of 10 approximately 30 nm can be heated well by an AEM field at a rate of 18 degrees C/wt%-minute; the fluorescence of ICG was extensively enhanced by NGPs; LHRH-coated gold nanoparticles provided as much cancer specificity as LHRH alone.	ferryl iron	26-31	gonadotropin releasing hormone 1	Homo sapiens	215-219
18061239-8	2008	The high efficiency of the composite Fe(0)/Fe3O4 for Cr(VI) reduction is discussed in terms of a special mechanism where an electron is transferred from Fe(0) to magnetite to reduce Fe(oct)3+ to Fe(oct)2+, which is active for Cr(VI) reduction.	ferryl iron	43-48	POU class 5 homeobox 1	Homo sapiens	182-190
18061239-8	2008	The high efficiency of the composite Fe(0)/Fe3O4 for Cr(VI) reduction is discussed in terms of a special mechanism where an electron is transferred from Fe(0) to magnetite to reduce Fe(oct)3+ to Fe(oct)2+, which is active for Cr(VI) reduction.	ferryl iron	43-48	POU class 2 homeobox 2	Homo sapiens	195-203
18464374-1	2008	In this study, size and surface effects on temperature and frequency dependent magnetic properties of superparamagnetic Fe3O4 nanoparticles in a size range of 1.1-11 nm are investigated by SPR technique.	ferryl iron	120-125	sepiapterin reductase	Homo sapiens	189-192
18290338-8	2008	Our study results showed: Fe3O4 particles at a size range of 10 approximately 30 nm can be heated well by an AEM field at a rate of 18 degrees C/wt%-minute; the fluorescence of ICG was extensively enhanced by NGPs; LHRH-coated gold nanoparticles provided as much cancer specificity as LHRH alone.	ferryl iron	26-31	gonadotropin releasing hormone 1	Homo sapiens	285-289
18290338-9	2008	Combining these properties in one entity, i.e., LHRH/ICG linked, gold-coated Fe3O4 nanoparticles, can be a tumor-specific nano-agent for optical detection and electro-magnetically induced hyperthermia for breast cancer.	ferryl iron	77-82	gonadotropin releasing hormone 1	Homo sapiens	48-52
18290339-4	2008	In our studies, we conjugated Fe3O4 nanoparticles (20-30 nm) with [D-Trp6]LHRH (Triptorelin), a decapeptide analog of LHRH currently used for treatment of sex-hormone-dependent tumors.	ferryl iron	30-35	transient receptor potential cation channel subfamily C member 6	Homo sapiens	69-73
18290339-4	2008	In our studies, we conjugated Fe3O4 nanoparticles (20-30 nm) with [D-Trp6]LHRH (Triptorelin), a decapeptide analog of LHRH currently used for treatment of sex-hormone-dependent tumors.	ferryl iron	30-35	gonadotropin releasing hormone 1	Homo sapiens	74-78
18290339-4	2008	In our studies, we conjugated Fe3O4 nanoparticles (20-30 nm) with [D-Trp6]LHRH (Triptorelin), a decapeptide analog of LHRH currently used for treatment of sex-hormone-dependent tumors.	ferryl iron	30-35	gonadotropin releasing hormone 1	Homo sapiens	118-122
18290339-5	2008	Conjugation of [D-Trp6]LHRH to Fe3O4 particles retained its binding affinity and biological activity for the LHRH receptor.	ferryl iron	31-36	transient receptor potential cation channel subfamily C member 6	Homo sapiens	18-22
18290339-5	2008	Conjugation of [D-Trp6]LHRH to Fe3O4 particles retained its binding affinity and biological activity for the LHRH receptor.	ferryl iron	31-36	gonadotropin releasing hormone 1	Homo sapiens	23-27
18290339-5	2008	Conjugation of [D-Trp6]LHRH to Fe3O4 particles retained its binding affinity and biological activity for the LHRH receptor.	ferryl iron	31-36	gonadotropin releasing hormone 1	Homo sapiens	109-113
17393156-2	2007	The immunosensor was fabricated by immobilizing anti-CEA on epoxysilane-modified core-shell magnetic Fe3O4/SiO2 nanoparticles.	ferryl iron	101-106	CEA cell adhesion molecule 3	Homo sapiens	53-56
17899439-6	2007	An interesting consequence of the presence of soluble Fe(+2) was the formation of Prussian Blue, Fe(4)[Fe(CN)(6)](3), which has been suggested as a possible reservoir of HCN in the initial prebiotic conditions on the Earth.	ferryl iron	97-102	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	170-173
17706825-0	2007	Activity and stability of alkaline phosphatase (ALP) immobilized onto magnetic nanoparticles (Fe3O4).	ferryl iron	94-99	alkaline phosphatase, placental	Homo sapiens	26-46
17706825-0	2007	Activity and stability of alkaline phosphatase (ALP) immobilized onto magnetic nanoparticles (Fe3O4).	ferryl iron	94-99	alkaline phosphatase, placental	Homo sapiens	48-51
17393156-12	2007	Figure This study introduced a magnetocontrolled electrochemical immunosensing strategy based on antibody-functionalized magnetic core-shell Fe3O4/SiO2 nanoparticles for the determination of carcinoembryonic antigen in human serum.	ferryl iron	141-146	CEA cell adhesion molecule 3	Homo sapiens	191-215
15221484-3	2004	The bioinorganic community was shocked, as the structures of the active sites of CODH and ACS, the C- and A-cluster, respectively, which each had been predicted to consist of a [Fe(4)S(4)] cluster bridged to a single Ni, revealed unexpected compositions and arrangements.	ferryl iron	178-184	acyl-CoA synthetase short chain family member 2	Homo sapiens	90-93
17221237-0	2007	Preparation of Fe3O4-C18 nano-magnetic composite materials and their cleanup properties for organophosphorous pesticides.	ferryl iron	15-20	Bardet-Biedl syndrome 9	Homo sapiens	21-24
17221237-1	2007	Magnetic Fe3O4-C18 composite nanoparticles of approximately 5-10 nm in size were synthesized and characterized by IR spectroscopy, atomic absorption spectroscopy, X-ray diffraction, and transmission electron microscopy.	ferryl iron	9-14	Bardet-Biedl syndrome 9	Homo sapiens	15-18
17221237-2	2007	The magnetic Fe3O4-C18 composite nanoparticles were applied for cleanup and enrichment of organophosphorous pesticides.	ferryl iron	13-18	Bardet-Biedl syndrome 9	Homo sapiens	19-22
17221237-3	2007	Comparative studies were carried out between magnetic Fe3O4-C18 composite nanoparticles and common C18 materials.	ferryl iron	54-59	Bardet-Biedl syndrome 9	Homo sapiens	60-63
17221237-5	2007	The cleanup and enrichment properties of magnetic Fe3O4-C18 composite nanoparticles are comparable with those of common C18 materials for enrichment of organophosphorous pesticides, but the cleanup and enrichment are faster and easier to perform.	ferryl iron	50-55	Bardet-Biedl syndrome 9	Homo sapiens	56-59
16800458-0	2006	Magnetic core-shell Fe3O4@Ag nanoparticles coated carbon paste interface for studies of carcinoembryonic antigen in clinical immunoassay.	ferryl iron	20-25	CEA cell adhesion molecule 3	Homo sapiens	88-112
16800458-1	2006	This study demonstrates a novel approach toward development of advanced immunosensors based on chemically functionalized core-shell Fe3O4@Ag magnetic nanoparticles, and the preparation, characterization, and measurement of relevant properties of the immunosensor useful for the detection of carcinoembryonic antigen (CEA) in clinical immunoassay.	ferryl iron	132-137	CEA cell adhesion molecule 3	Homo sapiens	291-315
16800458-1	2006	This study demonstrates a novel approach toward development of advanced immunosensors based on chemically functionalized core-shell Fe3O4@Ag magnetic nanoparticles, and the preparation, characterization, and measurement of relevant properties of the immunosensor useful for the detection of carcinoembryonic antigen (CEA) in clinical immunoassay.	ferryl iron	132-137	CEA cell adhesion molecule 3	Homo sapiens	317-320
16448661-0	2006	Fe3O4 and gamma-Fe2O3 nanoparticles for the adsorption of Co2+ from aqueous solution.	ferryl iron	0-5	complement C2	Homo sapiens	58-61
16448661-1	2006	The adsorption of Co2+ ions from nitrate solutions using iron oxide nanoparticles of magnetite (Fe3O4) and maghemite (gamma-Fe2O3) has been studied.	ferryl iron	96-101	complement C2	Homo sapiens	18-21
16448661-5	2006	Co2+ ions were also recovered by dilute nitric acid from the loaded gamma-Fe2O3 and Fe3O4 with an efficiency of 86 and 30%, respectively.	ferryl iron	84-89	complement C2	Homo sapiens	0-3
16448661-7	2006	The surface adsorption of Co2+ on Fe3O4 and gamma-Fe2O3 nanoparticles has been found to have the same mechanism of ion exchange reaction between Co2+ in the solution and proton bonded on the particle surface.	ferryl iron	34-39	complement C2	Homo sapiens	26-29
16448661-7	2006	The surface adsorption of Co2+ on Fe3O4 and gamma-Fe2O3 nanoparticles has been found to have the same mechanism of ion exchange reaction between Co2+ in the solution and proton bonded on the particle surface.	ferryl iron	34-39	complement C2	Homo sapiens	145-148
16448661-8	2006	The conditional equilibrium constants of surface adsorption of Co2+ on Fe3O4 and gamma-Fe2O3 nanoparticles have been determined to be log K=-3.3+/-0.3 and -3.1+/-0.2, respectively.	ferryl iron	71-76	complement C2	Homo sapiens	63-66
16448661-9	2006	The structural loading of Co2+ ions into Fe3O4 lattice has been found to be the ion exchange reaction between Co2+ and Fe2+ while that into gamma-Fe2O3 lattice to fill its vacancy.	ferryl iron	41-46	complement C2	Homo sapiens	26-29
16448661-9	2006	The structural loading of Co2+ ions into Fe3O4 lattice has been found to be the ion exchange reaction between Co2+ and Fe2+ while that into gamma-Fe2O3 lattice to fill its vacancy.	ferryl iron	41-46	complement C2	Homo sapiens	110-113
17348702-8	2007	We have demonstrated the applicability of C18-functionalized Fe3O4 nanoparticles in the detection of in vitro phosphorylation sites on the myelin basic protein, and at least 17 phosphopeptides were identified, including one previously uncharacterized site.	ferryl iron	61-66	myelin basic protein	Homo sapiens	139-159
16771558-1	2006	Spin-dependent electron transport in individual magnetite (Fe3O4) nanowires contacted with normal metallic electrodes was investigated.	ferryl iron	59-64	spindlin 1	Homo sapiens	0-4
15880500-1	2005	STM tips made from antiferromagnetic MnNi have been used to investigate the atomic structure of the (001) and (111) surfaces of Fe3O4.	ferryl iron	128-133	sulfotransferase family 1A member 3	Homo sapiens	0-3
15046341-4	2004	RDX is transformed by Fe(II) in aqueous suspensions of magnetite (Fe3O4).	ferryl iron	66-71	radixin	Homo sapiens	0-3
33773319-1	2021	A novel composite (CNTs-Fe3O4) was synthesized by a ball-milling strategy and characterized by BET, SEM, FTIR, XRD and VSM.	ferryl iron	24-29	delta/notch like EGF repeat containing	Homo sapiens	95-98
14524461-11	2003	Comparison of TPR profiles with the position of light-off curves in 2-monochlorophenol decomposition led to the conclusion that Fe3O4 species are the active phase under conditions that facilitate redox cycling between Fe3+ and Fe2+ ions.	ferryl iron	128-133	translocated promoter region, nuclear basket protein	Homo sapiens	14-17
11368929-6	2001	We propose that the protonated form of ferryl myoglobin (Fe(4+) - OH(-)) is the reactive species regulating the peroxidatic activity of myoglobin.	ferryl iron	57-65	myoglobin	Homo sapiens	46-55
11368929-6	2001	We propose that the protonated form of ferryl myoglobin (Fe(4+) - OH(-)) is the reactive species regulating the peroxidatic activity of myoglobin.	ferryl iron	57-65	myoglobin	Homo sapiens	136-145
9441619-0	1997	The Co2+ Adsorption Properties of Al2O3, Fe2O3, Fe3O4, TiO2, and MnO2 Evaluated by Modeling with the Frumkin Isotherm Adsorption of Co(II) ions on metal oxides is related to radioactive 60Co(II) (de)contamination of nuclear power plants, Co(II) ion retention in soils as a plant nutrient, concentration of Co(II) in deep-sea manganese nodules, and other applications.	ferryl iron	48-53	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	132-138
10004949-0	1993	Spin-Hamiltonian analysis for high-spin Fe2+ and Fe4+ ions at orthorhombic sites in YBa2(Cu1-xFex)3O7- delta and related oxides.	ferryl iron	49-53	spindlin 1	Homo sapiens	0-4
10004949-0	1993	Spin-Hamiltonian analysis for high-spin Fe2+ and Fe4+ ions at orthorhombic sites in YBa2(Cu1-xFex)3O7- delta and related oxides.	ferryl iron	49-53	spindlin 1	Homo sapiens	35-39
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	25-30	angiotensin-converting enzyme	Sus scrofa	50-53
33773653-0	2021	Novel monoclonal antibody-sandwich immunochromatographic assay based on Fe3O4/Au nanoparticles for rapid detection of fish allergen parvalbumin.	ferryl iron	72-77	parvalbumin	Homo sapiens	132-143
33798580-1	2021	This study presents a novel, economical, and environmentally technique for synthesizing magnetic palladium complex conjugated to activated calcium lignosulfonate with triethylenetetramine (Fe3O4@lignosulfonate@triethylenetetramine@Pd complex (FLT-Pd complex)) as a practical and air-stable catalyst.	ferryl iron	189-194	fms related receptor tyrosine kinase 1	Homo sapiens	243-246
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	25-30	angiotensin-converting enzyme	Sus scrofa	68-71
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	25-30	angiotensin-converting enzyme	Sus scrofa	68-71
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	55-60	angiotensin-converting enzyme	Sus scrofa	50-53
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	55-60	angiotensin-converting enzyme	Sus scrofa	68-71
33807119-2	2021	A new affinity medium of Fe3O4@ZIF-90 immobilized ACE (Fe3O4@ZIF-90-ACE) was prepared and used in the purification of ACE inhibitory peptides from Wakame (Undaria pinnatifida) protein hydrolysate (<5 kDa).	ferryl iron	55-60	angiotensin-converting enzyme	Sus scrofa	68-71
33807119-3	2021	The Fe3O4@ZIF-90 nanoparticles were prepared by a one-pot synthesis and crude ACE extract from pig lung was immobilized onto it, which exhibited excellent stability and reusability.	ferryl iron	4-9	angiotensin-converting enzyme	Sus scrofa	78-81
33807119-4	2021	A novel ACE inhibitory peptide, KNFL (inhibitory concentration 50, IC50 = 225.87 muM) was identified by affinity purification using Fe3O4@ZIF-90-ACE combined with reverse phase-high performance liquid chromatography (RP-HPLC) and MALDI-TOF mass spectrometry.	ferryl iron	132-137	angiotensin-converting enzyme	Sus scrofa	8-11
33807119-6	2021	This demonstrates that affinity purification using Fe3O4@ZIF-90-ACE is a highly efficient method for separating ACE inhibitory peptides from complex protein mixtures and the purified peptide KNFL could be developed as a functional food ingredients against hypertension.	ferryl iron	51-56	angiotensin-converting enzyme	Sus scrofa	64-67
33807119-6	2021	This demonstrates that affinity purification using Fe3O4@ZIF-90-ACE is a highly efficient method for separating ACE inhibitory peptides from complex protein mixtures and the purified peptide KNFL could be developed as a functional food ingredients against hypertension.	ferryl iron	51-56	angiotensin-converting enzyme	Sus scrofa	112-115
25779605-1	2015	A novel tumor-targeted drug delivery system (Fe3O4/CMCS-Rapa NPs) was prepared using magnetic Fe3O4/carboxymethylchitosan nanoparticles (Fe3O4/CMCS NPs) as carrier and rapamycin (Rapa) as the model anti-tumor drug.	ferryl iron	45-50	G protein signaling modulator 2	Homo sapiens	143-147
33763287-0	2021	Graphene Oxide/Polyvinyl Alcohol/Fe3O4 Nanocomposite: An Efficient Adsorbent for Co(II) Ion Removal.	ferryl iron	33-38	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	81-87
32795166-1	2021	In this study, the interaction of Fe3O4@CaAl-LDH@L-Dopa nanoparticles (NPs) with human serum albumin (HSA) was investigated in simulated physiological conditions applying UV-visible, fluorescence, and circular dichroism (CD) spectroscopic techniques.	ferryl iron	34-39	albumin	Homo sapiens	87-100
25779605-1	2015	A novel tumor-targeted drug delivery system (Fe3O4/CMCS-Rapa NPs) was prepared using magnetic Fe3O4/carboxymethylchitosan nanoparticles (Fe3O4/CMCS NPs) as carrier and rapamycin (Rapa) as the model anti-tumor drug.	ferryl iron	94-99	G protein signaling modulator 2	Homo sapiens	51-55
25779605-1	2015	A novel tumor-targeted drug delivery system (Fe3O4/CMCS-Rapa NPs) was prepared using magnetic Fe3O4/carboxymethylchitosan nanoparticles (Fe3O4/CMCS NPs) as carrier and rapamycin (Rapa) as the model anti-tumor drug.	ferryl iron	94-99	G protein signaling modulator 2	Homo sapiens	51-55
25779605-3	2015	The results showed that the synthesized Fe3O4/CMCS-Rapa NPs were spherical in shape with an average size of 30+-2 nm, the saturated magnetization reached 67.1 emu/g, and the loading efficiency of Rapa was approximately 6.32+-0.34%.	ferryl iron	40-45	G protein signaling modulator 2	Homo sapiens	46-50
34922979-2	2022	Herein, we reported the synthesis of catalase-Fe3O4@ZIF-8 (CAT-Fe3O4@ZIF-8) through a novel amino-acid-boosted one-pot embedding strategy that synergically integrated catalase and magnetic Fe3O4 nanoparticles with ZIF-8.	ferryl iron	46-51	catalase	Homo sapiens	59-62
34922979-2	2022	Herein, we reported the synthesis of catalase-Fe3O4@ZIF-8 (CAT-Fe3O4@ZIF-8) through a novel amino-acid-boosted one-pot embedding strategy that synergically integrated catalase and magnetic Fe3O4 nanoparticles with ZIF-8.	ferryl iron	46-51	catalase	Homo sapiens	167-175
34922979-2	2022	Herein, we reported the synthesis of catalase-Fe3O4@ZIF-8 (CAT-Fe3O4@ZIF-8) through a novel amino-acid-boosted one-pot embedding strategy that synergically integrated catalase and magnetic Fe3O4 nanoparticles with ZIF-8.	ferryl iron	63-68	catalase	Homo sapiens	59-62
34922979-2	2022	Herein, we reported the synthesis of catalase-Fe3O4@ZIF-8 (CAT-Fe3O4@ZIF-8) through a novel amino-acid-boosted one-pot embedding strategy that synergically integrated catalase and magnetic Fe3O4 nanoparticles with ZIF-8.	ferryl iron	63-68	catalase	Homo sapiens	167-175
34922979-2	2022	Herein, we reported the synthesis of catalase-Fe3O4@ZIF-8 (CAT-Fe3O4@ZIF-8) through a novel amino-acid-boosted one-pot embedding strategy that synergically integrated catalase and magnetic Fe3O4 nanoparticles with ZIF-8.	ferryl iron	189-194	catalase	Homo sapiens	59-62
34922979-3	2022	As expected, CAT-Fe3O4@ZIF-8 exhibited enhanced catalytic activity compared with Fe3O4@ZIF-8, CAT@ZIF-8 and catalase.	ferryl iron	17-22	catalase	Homo sapiens	13-16
34922979-4	2022	Depending on the satisfactory performance of CAT-Fe3O4@ZIF-8, a colorimetric detection platform for phenol based on CAT-Fe3O4@ZIF-8 was constructed.	ferryl iron	49-54	catalase	Homo sapiens	116-119
34922979-4	2022	Depending on the satisfactory performance of CAT-Fe3O4@ZIF-8, a colorimetric detection platform for phenol based on CAT-Fe3O4@ZIF-8 was constructed.	ferryl iron	120-125	catalase	Homo sapiens	116-119
34922979-6	2022	Besides, CAT-Fe3O4@ZIF-8-based colorimetric detection platform has been verified to possess high stability and recyclability.	ferryl iron	13-18	catalase	Homo sapiens	9-12
34749259-1	2022	We investigated the potential carrier of milk beta-casein (beta-CN) and its interactions with 5-fluorouracil (5-FU) and iron oxide nanoparticles (Fe3O4 NPs).	ferryl iron	146-151	casein beta	Homo sapiens	46-57
34808196-0	2022	A reduced graphene oxide-Fe3O4 composite functionalized with cetyltrimethylammonium bromide for efficient adsorption of SARS-CoV-2 spike pseudovirus and human enteric viruses.	ferryl iron	25-30	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	131-136
34808196-2	2022	In this study, reduced graphene oxide (rGO)-Fe3O4 nanoparticles were decorated with cetyltrimethylammonium bromide (CTAB) to adsorb severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike pseudovirus and three human enteric viruses (HuNoV, HRV, and HAdV).	ferryl iron	44-49	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	193-198
34808196-5	2022	CTAB-functionalized rGO-Fe3O4 exhibited exceptionally high adsorption of HuNoV, HRV, HAdV and SARS-CoV-2 spike pseudovirus, with maximum adsorption capacities of 3.55 x 107, 7.01 x 107, 2.21 x 107 and 6.92 x 106 genome copies mg-1, respectively.	ferryl iron	24-29	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	105-110
34749259-0	2022	Molecular insights into the interaction of 5-fluorouracil and Fe3O4 nanoparticles with beta-casein: An experimental and theoretical study.	ferryl iron	62-67	casein beta	Homo sapiens	87-98
34749259-1	2022	We investigated the potential carrier of milk beta-casein (beta-CN) and its interactions with 5-fluorouracil (5-FU) and iron oxide nanoparticles (Fe3O4 NPs).	ferryl iron	146-151	apoptotic chromatin condensation inducer 1	Homo sapiens	59-66
34749259-3	2022	The fluorescence data indicated both Fe3O4 NPs and 5-FU could quench the intrinsic fluorescence of beta-CN.	ferryl iron	37-42	apoptotic chromatin condensation inducer 1	Homo sapiens	99-106
34749259-4	2022	Fluorescence measurements showed that the single interaction of beta-CN with 5-FU or Fe3O4 NPs was static, while reacted beta-CN with both 5-FU and Fe3O4 NPs simultaneously showed a dynamic quenching.	ferryl iron	85-90	apoptotic chromatin condensation inducer 1	Homo sapiens	64-71
34749259-4	2022	Fluorescence measurements showed that the single interaction of beta-CN with 5-FU or Fe3O4 NPs was static, while reacted beta-CN with both 5-FU and Fe3O4 NPs simultaneously showed a dynamic quenching.	ferryl iron	148-153	apoptotic chromatin condensation inducer 1	Homo sapiens	121-128
34749259-9	2022	The outcomes highlighted that beta-CN protein could form a great bind with 5-FU and Fe3O4 NPs ligands (supporting the zeta potential assay results) by independent binding sites.	ferryl iron	84-89	apoptotic chromatin condensation inducer 1	Homo sapiens	30-37
34780754-4	2022	To support this, the facilitated target nanoparticles of Fe3O4@SiO2-C18 were synthesized at a size of 12-13 nm with a magnetic saturation of 40 emu/g.	ferryl iron	57-62	Bardet-Biedl syndrome 9	Homo sapiens	68-71
34736102-5	2022	The aptamers of epithelial cell adhesion molecule (EpCAM) modified AuPt NPs were assembled with Co-MOF/Fe3O4/Ag NSs, which generated strong detection and reference signals at -0.7 V and 0.1 V, respectively.	ferryl iron	103-108	epithelial cell adhesion molecule	Homo sapiens	16-49
34736102-5	2022	The aptamers of epithelial cell adhesion molecule (EpCAM) modified AuPt NPs were assembled with Co-MOF/Fe3O4/Ag NSs, which generated strong detection and reference signals at -0.7 V and 0.1 V, respectively.	ferryl iron	103-108	epithelial cell adhesion molecule	Homo sapiens	51-56
34944671-5	2021	In the aorta, Fe3O4@PEG treatment increased eNOS, iNOS, NRF2, and DMT1 gene expression (considered main effects).	ferryl iron	14-19	nitric oxide synthase 3	Rattus norvegicus	44-48
34364225-3	2022	Results showed that AO7 removal rate, COD removal rate, and sulfate reduction were enhanced with the addition of Fe3O4 under various influent AO7 concentrations (153 mgCOD/L - 1787 mgCOD/L).	ferryl iron	113-118	ring finger protein 25	Homo sapiens	20-23
34364225-3	2022	Results showed that AO7 removal rate, COD removal rate, and sulfate reduction were enhanced with the addition of Fe3O4 under various influent AO7 concentrations (153 mgCOD/L - 1787 mgCOD/L).	ferryl iron	113-118	ring finger protein 25	Homo sapiens	142-145
34364225-4	2022	According to the proposed pathway for the degradation of AO7, more intermediates (2-hydroxy-1,4-naphthoquinone, phthalide, 4-methylphenol) were produced in the presence of Fe3O4.	ferryl iron	172-177	ring finger protein 25	Homo sapiens	57-60
34878783-3	2021	Through comparison of pristine and W-doped Fe3O4/Fe2O3 phase boundaries, it is revealed that the spin polarization of O atoms at the interface plays an important role in the periodic segregation of W atoms.	ferryl iron	43-48	spindlin 1	Homo sapiens	97-101
34661718-0	2022	Hydroxyurea-loaded Fe3O4/SiO2/chitosan-g-mPEG2000 nanoparticles; pH-dependent drug release and evaluation of cell cycle arrest and altering p53 and lincRNA-p21 genes expression.	ferryl iron	19-24	tumor protein p53 pathway corepressor 1	Homo sapiens	148-159
34969977-0	2021	XPS and structural studies of Fe3O4-PTMS-NAS@Cu as a novel magnetic natural asphalt base network and recoverable nanocatalyst for the synthesis of biaryl compounds.	ferryl iron	30-35	parathymosin	Homo sapiens	36-40
34969977-2	2021	Afterwards, Cupper (I) and Cu (II) was grafted on Fe3O4-PTMS-NAS.	ferryl iron	50-55	parathymosin	Homo sapiens	56-60
34969977-3	2021	Moreover, it is worth mentioning that the synthesized the novel magnetic nanocatalyst (Fe3O4-PTMS-NAS@Cu) was successfully used in Suzuki and Stille coupling reactions.	ferryl iron	87-92	parathymosin	Homo sapiens	93-97
34969977-4	2021	The Fe3O4-PTMS-NAS@Cu MNPs were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), inductively coupled plasma (ICP), BET and X-ray photoelectron spectroscopy (XPS) analysis.	ferryl iron	4-9	parathymosin	Homo sapiens	10-14
34934053-3	2021	The Fe3O4@SiO2@UiO-66-TPP was properly characterized by TEM, FT-IR, BET, VSM and Zeta potential measurement.	ferryl iron	4-9	delta/notch like EGF repeat containing	Homo sapiens	68-71
34882274-1	2021	A sensitive label-based SERS strategy composed of magnetic bimetallic nanoparticles Fe3O4@Ag@Au, specific aptamer, and Bradford method was developed for the quantitative determination of cardiac troponin I (cTnI) in human serum.	ferryl iron	84-89	troponin I3, cardiac type	Homo sapiens	187-205
34882274-1	2021	A sensitive label-based SERS strategy composed of magnetic bimetallic nanoparticles Fe3O4@Ag@Au, specific aptamer, and Bradford method was developed for the quantitative determination of cardiac troponin I (cTnI) in human serum.	ferryl iron	84-89	troponin I3, cardiac type	Homo sapiens	207-211
34944671-5	2021	In the aorta, Fe3O4@PEG treatment increased eNOS, iNOS, NRF2, and DMT1 gene expression (considered main effects).	ferryl iron	14-19	nitric oxide synthase 2	Rattus norvegicus	50-54
34944671-5	2021	In the aorta, Fe3O4@PEG treatment increased eNOS, iNOS, NRF2, and DMT1 gene expression (considered main effects).	ferryl iron	14-19	NFE2 like bZIP transcription factor 2	Rattus norvegicus	56-60
34944671-5	2021	In the aorta, Fe3O4@PEG treatment increased eNOS, iNOS, NRF2, and DMT1 gene expression (considered main effects).	ferryl iron	14-19	RoBo-1	Rattus norvegicus	66-70
34944671-6	2021	In the liver, Fe3O4@PEG significantly elevated eNOS and iNOS gene expression in SHRu vs. SHRc, as well as DMT1 and FTH1 gene expression (considered main effects).	ferryl iron	14-19	nitric oxide synthase 3	Rattus norvegicus	47-51
34944671-6	2021	In the liver, Fe3O4@PEG significantly elevated eNOS and iNOS gene expression in SHRu vs. SHRc, as well as DMT1 and FTH1 gene expression (considered main effects).	ferryl iron	14-19	nitric oxide synthase 2	Rattus norvegicus	56-60
34944671-6	2021	In the liver, Fe3O4@PEG significantly elevated eNOS and iNOS gene expression in SHRu vs. SHRc, as well as DMT1 and FTH1 gene expression (considered main effects).	ferryl iron	14-19	RoBo-1	Rattus norvegicus	106-110
34944671-6	2021	In the liver, Fe3O4@PEG significantly elevated eNOS and iNOS gene expression in SHRu vs. SHRc, as well as DMT1 and FTH1 gene expression (considered main effects).	ferryl iron	14-19	ferritin heavy chain 1	Rattus norvegicus	115-119
34883265-4	2022	Moreover, the water maze test showed that compared with hUC-MSCs only, Fe3O4@PDA-labeled hUC-MSCs improved the cognitive ability of APP/PS1 transgenic mice more significantly.	ferryl iron	71-76	presenilin 1	Mus musculus	136-139
34739963-3	2021	The sorbent, TA-Ti-PA@Fe3O4, exhibited satisfactory selectivity for the phosphopeptides in the tryptic digest of beta-casein, and can eliminate the interference components in 1000-fold excess of bovine serum albumin.	ferryl iron	22-27	albumin	Rattus norvegicus	202-215
34883265-5	2022	Other experimental data showed that the expression of essential proteins in the hippocampus, such as Abeta, synaptophysin, brain-derived neurotrophic factor, are affected by Fe3O4@PDA coated-hUC-MSCs.	ferryl iron	174-179	amyloid beta (A4) precursor protein	Mus musculus	101-106
34883265-5	2022	Other experimental data showed that the expression of essential proteins in the hippocampus, such as Abeta, synaptophysin, brain-derived neurotrophic factor, are affected by Fe3O4@PDA coated-hUC-MSCs.	ferryl iron	174-179	synaptophysin	Mus musculus	108-121
34883265-5	2022	Other experimental data showed that the expression of essential proteins in the hippocampus, such as Abeta, synaptophysin, brain-derived neurotrophic factor, are affected by Fe3O4@PDA coated-hUC-MSCs.	ferryl iron	174-179	brain derived neurotrophic factor	Mus musculus	123-156
34766615-0	2021	Surface specifically modified NK-92 cells with CD56 antibody conjugated superparamagnetic Fe3O4 nanoparticles for magnetic targeting immunotherapy of solid tumors.	ferryl iron	90-95	neural cell adhesion molecule 1	Homo sapiens	47-51
34912778-1	2021	Cellulose, as a green and available phytochemical, was immobilized on the surface of magnetite nanoparticles then doped with imidazole and Co. complex (Fe3O4@CNF ~ ImSBL ~ Co.) and used as a water-dispersible, recyclable and efficient nano catalyst for the synthesis of C-C cross-coupling reactions including fluoride-free Hiyama and Suzuki reactions in an aqueous medium as an efficient and vital solvent, due to their high application and importance in various fields of science.	ferryl iron	152-157	NPHS1 adhesion molecule, nephrin	Homo sapiens	158-161
34766615-4	2021	Anti-CD56 antibodies were conjugated with Fe3O4 nanoparticles, which could specifically bind with NK-92 cells endowing them with a magnetic field driven targeting ability.	ferryl iron	42-47	neural cell adhesion molecule 1	Homo sapiens	5-9
34869259-4	2021	In the modified CF electrode with SRBs, a considerable improvement in the bioelectrochemical operation was observed, where the power density (309 +- 13 mW/m2) was 1.86 times higher than bare CF with SRBs (166 +- 11 mW/m2), suggesting better bioelectrochemical performance of an SRB-enriched Fe3O4@CF anode in the MFC.	ferryl iron	291-296	chaperonin containing TCP1 subunit 4	Homo sapiens	278-281
34762403-5	2021	Benefiting from the outstanding magnetic responsiveness and multiaffinity sites (Ti-O, Fe-O, and NH2 groups), the Fe3O4/TiO2@Ti3C2Tx composites possessed excellent enrichment performance with high sensitivity (0.1 fmol muL-1), excellent selectivity (beta-casein: bovine serum albumin = 1:5000, molar ratio), good repeatability (5 times), and high enrichment capacity (200 mg g-1).	ferryl iron	114-119	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	219-224
34762403-5	2021	Benefiting from the outstanding magnetic responsiveness and multiaffinity sites (Ti-O, Fe-O, and NH2 groups), the Fe3O4/TiO2@Ti3C2Tx composites possessed excellent enrichment performance with high sensitivity (0.1 fmol muL-1), excellent selectivity (beta-casein: bovine serum albumin = 1:5000, molar ratio), good repeatability (5 times), and high enrichment capacity (200 mg g-1).	ferryl iron	114-119	albumin	Homo sapiens	270-283
34756250-3	2021	Thus, a new type of magnetic dual affinity epitope molecularly imprinted polymer coated on Fe3O4 nanoparticles (Fe3O4@DEMIP) was successfully prepared for specific recognition of Trf.	ferryl iron	91-96	transferrin	Homo sapiens	179-182
34756250-3	2021	Thus, a new type of magnetic dual affinity epitope molecularly imprinted polymer coated on Fe3O4 nanoparticles (Fe3O4@DEMIP) was successfully prepared for specific recognition of Trf.	ferryl iron	112-117	transferrin	Homo sapiens	179-182
34756250-6	2021	Results showed that Fe3O4@DEMIP exhibited excellent specific recognition ability adsorption capacity toward Trf, with an adsorption of 43.96 mg g-1 (RSD = 3.28%) and a more satisfactory imprinting factor (about 6.60) than that of other reported imprinting methods.	ferryl iron	20-25	transferrin	Homo sapiens	108-111
34756250-8	2021	Furthermore, the Fe3O4@DEMIP coupled with high-performance liquid chromatography (HPLC) analysis was successfully used for specific recognition of Trf in biosamples.	ferryl iron	17-22	transferrin	Homo sapiens	147-150
34869259-6	2021	The SRB-enriched Fe3O4@CF anode also assists in enhancing MFC performance in terms of COD removal (>75%), indicating efficient biodegradability of tannery wastewater and a higher electron transfer rate from SRBs to the conductive anode.	ferryl iron	17-22	chaperonin containing TCP1 subunit 4	Homo sapiens	4-7
34450145-3	2021	The synthesized Fe3O4@CQD@AP-B(OH)2 was characterized by FE-SEM, EDS, XRD, VSM and ICP-OES analysis and its fluorescence property was studied.	ferryl iron	16-21	arginyl aminopeptidase	Homo sapiens	26-30
34171735-0	2021	Magnetic field-aligned Fe3O4-coated silver magnetoplasmonic nanochain with enhanced sensitivity for detection of Siglec-15.	ferryl iron	23-28	sialic acid binding Ig like lectin 15	Homo sapiens	113-122
34364494-0	2021	Signal amplification of novel sandwich-type genosensor via catalytic redox-recycling on platform MWCNTs/Fe3O4@TMU-21 for BRCA1 gene detection.	ferryl iron	104-109	BRCA1 DNA repair associated	Homo sapiens	121-126
34364494-1	2021	The MWCNTs/Fe3O4@TMU-21 as a novel electrochemical sandwich-type genosensor was fabricated to detect the BRCA1 gene using the redox-cycling ferrocene functionalized reporter label probe (r-Fc-DNA).	ferryl iron	11-16	BRCA1 DNA repair associated	Homo sapiens	105-110
34364505-3	2021	Inspired by the prevalence of hydrophilic interaction chromatography for glycopeptide enrichment, a novel magnetic mesoporous silica nanomaterial (Fe3O4@mSiO2-TSG) with strongly hydrophilic property was developed through a one-pot method.	ferryl iron	147-152	twisted gastrulation BMP signaling modulator 1	Homo sapiens	159-162
34364505-5	2021	Apart from excellent hydrophilicity, Fe3O4@mSiO2-TSG also was equipped with large specific surface area, ordered mesopore channels and great magnetic responsiveness.	ferryl iron	37-42	twisted gastrulation BMP signaling modulator 1	Homo sapiens	49-52
34364505-6	2021	With all the advantages, Fe3O4@mSiO2-TSG displayed remarkable size-exclusion effect and considerable reusability.	ferryl iron	25-30	twisted gastrulation BMP signaling modulator 1	Homo sapiens	37-40
34633394-2	2021	GO is conjugated with Au@Ag and Fe3O4 nanoparticles, which facilitates it with SERS tracking and magnetic targeting abilities, followed by the covalent binding of the anti-HER2 antibody, thus allowing it to both actively and passively target SKBR3 cells, human breast cancer cells expressed with HER2.	ferryl iron	32-37	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	79-83
34215976-3	2021	To solve the problems, Fe3O4 MNPs were modified by poly(catechol) (Fe3O4/PCC MNPs) using a facile chemical co-precipitation method.	ferryl iron	23-28	crystallin gamma D	Homo sapiens	73-76
34215976-4	2021	The poly(catechol) modification improved both the dispersity and the surface negative charges of Fe3O4/PCC MNPs, which are beneficial to the catalytic activity of MNPs for organic degradation.	ferryl iron	97-102	crystallin gamma D	Homo sapiens	103-106
34215976-6	2021	As a result, the Fenton reaction with Fe3O4/PCC MNPs could efficiently degrade organic molecules, exampled by methylene blue (MB), in an expanded pH range between 3.0 and 10.0.	ferryl iron	38-43	crystallin gamma D	Homo sapiens	44-47
34215976-8	2021	This study demonstrated Fe3O4/PCC MNPs are a promising heterogeneous Fenton catalysts for organic degradation.	ferryl iron	24-29	crystallin gamma D	Homo sapiens	30-33
34810312-2	2021	We conducted the adsorption studies of potentially toxic metal ions (Cu2+, Co2+ and Cd2+) using the composite of Fe3O4 and zeolitic imidazole framework-8 (Fe3O4@ZIF-8) for the first time.	ferryl iron	113-118	CD2 molecule	Homo sapiens	84-87
34810312-2	2021	We conducted the adsorption studies of potentially toxic metal ions (Cu2+, Co2+ and Cd2+) using the composite of Fe3O4 and zeolitic imidazole framework-8 (Fe3O4@ZIF-8) for the first time.	ferryl iron	155-160	CD2 molecule	Homo sapiens	84-87
34810312-7	2021	To remove potentially toxic metals (Cu2+, Co2+ and Cd2+), the influence of adsorbent dosage, contact time, pH, and adsorbate concentration on the adsorption performance of Fe3O4@ZIF-8 was investigated.	ferryl iron	172-177	CD2 molecule	Homo sapiens	51-54
34810312-8	2021	The Langmuir isotherm accurately represented the adsorption processes, with absorption magnitudes of Fe3O4@ZIF-8 determined to be 46.82 mg g-1, 71.29 mg g-1 and 54.49 mg g-1 for Cu2+, Co2+ and Cd2+, respectively.	ferryl iron	101-106	CD2 molecule	Homo sapiens	193-196
34810312-9	2021	According to the adsorption mechanism analysis, the primary Cu2+, Co2+ and Cd2+ removal methods of Fe3O4@ZIF-8 were ion exchange and coordination bonds.	ferryl iron	99-104	CD2 molecule	Homo sapiens	75-78
34810312-10	2021	The uptake capacity of Cu2+, Co2+ and Cd2+ solution by Fe3O4@ZIF-8 were not significantly affected by the presence of counter ions.	ferryl iron	55-60	CD2 molecule	Homo sapiens	38-41
34810312-12	2021	This study concluded that the Fe3O4@ZIF-8 could be a viable candidate for eliminating potentially toxic metals (Cu2+, Co2+ and Cd2+).	ferryl iron	30-35	CD2 molecule	Homo sapiens	127-130
34778301-1	2021	Objective: The purpose of this study was to investigate the anticancer activity and the potential imaging use of the innovative combination of magnetic nanoparticles (MNPs)-Fe3O4, paclitaxel (PTX), and trastuzumab (Herceptin) in HER2-positive breast cancer.	ferryl iron	173-178	erb-b2 receptor tyrosine kinase 2	Homo sapiens	229-233
34714621-3	2021	Herein, Fe3O4- and MnO2-loaded biohybrid magnetic helical microrobots (BMHMs) based on Spirulina cells were presented for the first time, and their performance on Pb(II) removal was studied in detail.	ferryl iron	8-13	submaxillary gland androgen regulated protein 3B	Homo sapiens	163-169
34714628-3	2021	As a proof of concept, glucose oxidase (GOx) was immobilized onto a ferrimagnetic vortex iron oxide nanoring (Fe3O4 NR) functionalized with poly(ethylene glycol) of different molecular weights to construct a series of Fe3O4 NR@GOx with nanometer linking distances.	ferryl iron	110-115	hydroxyacid oxidase 1, liver	Mus musculus	23-38
34714628-3	2021	As a proof of concept, glucose oxidase (GOx) was immobilized onto a ferrimagnetic vortex iron oxide nanoring (Fe3O4 NR) functionalized with poly(ethylene glycol) of different molecular weights to construct a series of Fe3O4 NR@GOx with nanometer linking distances.	ferryl iron	110-115	hydroxyacid oxidase 1, liver	Mus musculus	227-230
34714628-3	2021	As a proof of concept, glucose oxidase (GOx) was immobilized onto a ferrimagnetic vortex iron oxide nanoring (Fe3O4 NR) functionalized with poly(ethylene glycol) of different molecular weights to construct a series of Fe3O4 NR@GOx with nanometer linking distances.	ferryl iron	218-223	hydroxyacid oxidase 1, liver	Mus musculus	23-38
34714628-3	2021	As a proof of concept, glucose oxidase (GOx) was immobilized onto a ferrimagnetic vortex iron oxide nanoring (Fe3O4 NR) functionalized with poly(ethylene glycol) of different molecular weights to construct a series of Fe3O4 NR@GOx with nanometer linking distances.	ferryl iron	218-223	hydroxyacid oxidase 1, liver	Mus musculus	40-43
34714628-3	2021	As a proof of concept, glucose oxidase (GOx) was immobilized onto a ferrimagnetic vortex iron oxide nanoring (Fe3O4 NR) functionalized with poly(ethylene glycol) of different molecular weights to construct a series of Fe3O4 NR@GOx with nanometer linking distances.	ferryl iron	218-223	hydroxyacid oxidase 1, liver	Mus musculus	227-230
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	29-34	hydroxyacid oxidase 1, liver	Mus musculus	60-63
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	29-34	hydroxyacid oxidase 1, liver	Mus musculus	147-150
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	47-52	hydroxyacid oxidase 1, liver	Mus musculus	21-24
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	47-52	hydroxyacid oxidase 1, liver	Mus musculus	60-63
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	47-52	hydroxyacid oxidase 1, liver	Mus musculus	147-150
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	159-164	hydroxyacid oxidase 1, liver	Mus musculus	21-24
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	159-164	hydroxyacid oxidase 1, liver	Mus musculus	60-63
34714628-5	2021	Compared to the free GOx and Fe3O4 NR mixture, Fe3O4 NR(D2)@GOx with an optimum linking distance of 1 nm exhibits a superior kinetic match between GOx and the Fe3O4 NR nanozyme and over a 400-fold higher cascade activity under AMF exposure.	ferryl iron	159-164	hydroxyacid oxidase 1, liver	Mus musculus	147-150
34645263-5	2021	Then, the self-assembled DNA nanoprisms contained three thiols/hanging arms that could capture miRNA-210 efficiently and were anchored to the Fe3O4@CdS octahedra via the Cd-S bond.	ferryl iron	142-147	CDP-diacylglycerol synthase 1	Homo sapiens	170-174
34835642-2	2021	Fe3O4-SnO2 nanoparticles were prepared by the carboxylation of the pivotal particles (Fe3O4) with an anionic surfactant to immobilize SnO2 nanoparticles.	ferryl iron	86-91	strawberry notch homolog 1	Homo sapiens	134-137
34585187-0	2021	A multimodal strategy of Fe3O4@ZIF-8/GOx@MnO2 hybrid nanozyme via TME modulation for tumor therapy.	ferryl iron	25-30	hydroxyacid oxidase 1	Homo sapiens	37-40
34522934-4	2021	Therefore, the resulting Fe3O4@TA/CuII SPMNPs could capture various CTCs (MCF-7, HepG2 and HeLa cells) with different expression levels of the epithelial cell adhesion molecule (EpCAM).	ferryl iron	25-30	epithelial cell adhesion molecule	Homo sapiens	143-176
34522934-4	2021	Therefore, the resulting Fe3O4@TA/CuII SPMNPs could capture various CTCs (MCF-7, HepG2 and HeLa cells) with different expression levels of the epithelial cell adhesion molecule (EpCAM).	ferryl iron	25-30	epithelial cell adhesion molecule	Homo sapiens	178-183
34677358-0	2021	Enhanced Plasmonic Biosensor Utilizing Paired Antibody and Label-Free Fe3O4 Nanoparticles for Highly Sensitive and Selective Detection of Parkinson"s alpha-Synuclein in Serum.	ferryl iron	70-75	synuclein alpha	Homo sapiens	150-165
34677358-3	2021	Herein, we developed a surface plasmon resonance (SPR) biosensor based on the label-free iron oxide nanoparticles (Fe3O4 NPs) and paired antibody for the highly sensitive and selective detection of alpha-syn in serum samples.	ferryl iron	115-120	synuclein alpha	Homo sapiens	198-207
34683725-7	2021	The adsorption capacity for Pb(II) was 389 mg g-1 (1.88 mmol g-1) and 249 mg g-1 (1.20 mmol g-1); while for Cd(II) was 269 mg g-1 (2.39 mmol g-1) and 264 mg g-1 (2.35 mmol g-1) for the Fe3O4+C and CoFe2O4+C, respectively.	ferryl iron	185-190	submaxillary gland androgen regulated protein 3B	Homo sapiens	28-34
34585187-8	2021	At the same time, the intrinsic photothermal effect of Fe3O4 upon 808 nm laser irradiation promoted the activity of MnO2 and GOx as oxidase, and Fe(II) as catalase-like, and ablated the primary tumor.	ferryl iron	55-60	hydroxyacid oxidase 1	Homo sapiens	125-128
34543021-2	2021	Herein, the novel efficient Ni2P/Fe3O4 porous nanosheets arrays supported on Ni foam (Ni2P/Fe3O4/NF) as alkaline OER catalysts were synthesized using structural and interfacial engineering.	ferryl iron	33-38	neurofascin	Homo sapiens	97-99
34543021-2	2021	Herein, the novel efficient Ni2P/Fe3O4 porous nanosheets arrays supported on Ni foam (Ni2P/Fe3O4/NF) as alkaline OER catalysts were synthesized using structural and interfacial engineering.	ferryl iron	91-96	neurofascin	Homo sapiens	97-99
34543021-3	2021	The three-dimensional (3D) porous hierarchical structure of Ni2P/Fe3O4/NF provides abundant active sites for OER and facilitates the electrolyte diffusion of ions and O2 liberation.	ferryl iron	65-70	neurofascin	Homo sapiens	71-73
34543021-5	2021	Consequently, the optimized Ni2P/Fe3O4/NF exhibits excellent OER performance with low overpotentials of 213 and 240 mV at 60 and 100 mA cm-2 in 1.0 M KOH, respectively, better than the RuO2/NF and most Ni/Fe-based OER catalysts.	ferryl iron	33-38	neurofascin	Homo sapiens	39-41
34639075-1	2021	In this study, interactions of Fe3O4 magnetic nanoparticles with serum albumin biomolecules in aqueous solutions were considered.	ferryl iron	31-36	albumin	Homo sapiens	71-78
34622194-7	2021	Mechanistic in vivo toxicity analysis showed a reduction in oxidative stress in carbon-modified alpha-Fe2O3 exposed zebrafish embryos compared to Fe3O4 due to despaired influential atomic interaction with sod1 protein along with significant less morphological abnormalities and apoptosis.	ferryl iron	146-151	superoxide dismutase 1, soluble	Danio rerio	205-209
34627266-6	2021	The as-obtained Fe3O4@PCBMA-SIM nanoparticles demonstrated more cytotoxicity against MDA-MB-231 than MCF-7 due to the higher expression of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR), which demonstrated that statins could effectively kill TNBC.	ferryl iron	16-21	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	139-187
34627266-6	2021	The as-obtained Fe3O4@PCBMA-SIM nanoparticles demonstrated more cytotoxicity against MDA-MB-231 than MCF-7 due to the higher expression of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR), which demonstrated that statins could effectively kill TNBC.	ferryl iron	16-21	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	189-194
34153864-4	2021	Benefiting from the co-deposition of polyethyleneimine and Fe3O4, the fabricated material showed significantly higher adsorption capacity (183.82 and 231.48 mg g-1 for Cu2+ and Cd2+) than that of raw cow dung (0.95 and 1.25 mg g-1 for Cu2+ and Cd2+).	ferryl iron	59-64	CD2 molecule	Bos taurus	177-180
34153864-4	2021	Benefiting from the co-deposition of polyethyleneimine and Fe3O4, the fabricated material showed significantly higher adsorption capacity (183.82 and 231.48 mg g-1 for Cu2+ and Cd2+) than that of raw cow dung (0.95 and 1.25 mg g-1 for Cu2+ and Cd2+).	ferryl iron	59-64	CD2 molecule	Bos taurus	244-247
34535254-3	2021	The obtained Fe3O4@MIL-100(Fe) showed satisfactory intrinsic dual enzyme mimetic activities, including peroxidase (POD)- and catalase (CAT)-like activities.	ferryl iron	13-18	catalase	Homo sapiens	135-138
34499835-4	2021	The adsorption capacities of HA-Ca/Fe3O4 for Pb2+, Cu2+, and Cd2+ were 208.33, 98.33, and 99.01 mg g-1, respectively.	ferryl iron	35-40	CD2 molecule	Homo sapiens	61-64
34499835-6	2021	Pb2+, Cu2+, and Cd2+ removal using HA-Ca/Fe3O4 occurred via ion exchange, complexation of O-containing functional groups, mineral precipitation, and pi-electron coordination.	ferryl iron	41-46	CD2 molecule	Homo sapiens	16-19
34499835-8	2021	In practice, HA-Ca/Fe3O4 can remove 99% Pb2+ and 91% Cu2+ and Cd2+ from real wastewater samples.	ferryl iron	19-24	CD2 molecule	Homo sapiens	62-65
34329032-4	2021	The as-synthesized GO-Fe3O4 composite was characterized by SEM, TEM, XRD, FTIR, BET and VSM.	ferryl iron	22-27	delta/notch like EGF repeat containing	Homo sapiens	80-83
34505435-15	2021	UiO-66-NH2 was grown in situ on the surface of Fe3O4 by a solvothermal method to form a Zr-MOFs layer, and aptamer-CD63 was covalently bonded to the amino group of the organic ligand of the MOFs.	ferryl iron	47-52	CD63 molecule	Homo sapiens	115-119
34551040-2	2021	Here, through density functional calculations, we investigated the effect of the spin-orbit interaction on the magnetic ground state of Eu doped magnetite (Fe3O4:EuFe).	ferryl iron	156-161	spindlin 1	Homo sapiens	81-85
34551040-4	2021	Consequently, because of smaller spin cancellation between the cations on the tetrahedral site (FeTet and EuTet) and the cations on the octahedral sites (FeOct), Fe3O4:EuFe exhibits a maximum saturation magnetisation of 9.451 muB per f.u.	ferryl iron	162-167	spindlin 1	Homo sapiens	33-37
34632217-3	2021	The resulted Schiff base complex of copper coated on epoxy-modified Fe3O4@SiO2 MNPs was characterized and confirmed via different analyses such as FT-IR, TGA, XRD, VSM, FE-SEM, TEM, ICP, EDX, and BET.	ferryl iron	68-73	delta/notch like EGF repeat containing	Homo sapiens	196-199
34494164-3	2021	The adsorbent with two-dimensional (2D) morphology offered high surface area and abundant Gd3+ contents for phosphopeptides enrichment, on which Fe3O4 with positive electricity incorporated the magnetic properties.	ferryl iron	145-150	GRDX	Homo sapiens	90-93
34511910-0	2021	Magnetite Fe3O4 Nanoparticles Enhance Mild Microwave Ablation of Tumor by Activating the IRE1-ASK1-JNK Pathway and Inducing Endoplasmic Reticulum Stress.	ferryl iron	10-15	endoplasmic reticulum (ER) to nucleus signalling 2	Mus musculus	89-93
34511910-0	2021	Magnetite Fe3O4 Nanoparticles Enhance Mild Microwave Ablation of Tumor by Activating the IRE1-ASK1-JNK Pathway and Inducing Endoplasmic Reticulum Stress.	ferryl iron	10-15	mitogen-activated protein kinase kinase kinase 5	Mus musculus	94-98
34511910-0	2021	Magnetite Fe3O4 Nanoparticles Enhance Mild Microwave Ablation of Tumor by Activating the IRE1-ASK1-JNK Pathway and Inducing Endoplasmic Reticulum Stress.	ferryl iron	10-15	mitogen-activated protein kinase 8	Mus musculus	99-102
34511910-5	2021	Results: The IRE1-ASK1-JNK pathway was strongly activated in A375 cells treated with both Fe3O4 NPs and mild microwave.	ferryl iron	90-95	endoplasmic reticulum (ER) to nucleus signalling 2	Mus musculus	13-17
34511910-5	2021	Results: The IRE1-ASK1-JNK pathway was strongly activated in A375 cells treated with both Fe3O4 NPs and mild microwave.	ferryl iron	90-95	mitogen-activated protein kinase kinase kinase 5	Mus musculus	18-22
34511910-5	2021	Results: The IRE1-ASK1-JNK pathway was strongly activated in A375 cells treated with both Fe3O4 NPs and mild microwave.	ferryl iron	90-95	mitogen-activated protein kinase 8	Mus musculus	23-26
34475406-2	2021	Inspired by this biochemical pathway, we demonstrate the reactive oxygen species (ROS) induced tumor therapy by integrating lactate oxidase (LOx) and catalase (CAT) into Fe3O4 nanoparticle/indocyanine green (ICG) co-loaded hybrid nanogels (designated as FIGs-LC).	ferryl iron	170-175	lysyl oxidase	Homo sapiens	141-144
34475406-2	2021	Inspired by this biochemical pathway, we demonstrate the reactive oxygen species (ROS) induced tumor therapy by integrating lactate oxidase (LOx) and catalase (CAT) into Fe3O4 nanoparticle/indocyanine green (ICG) co-loaded hybrid nanogels (designated as FIGs-LC).	ferryl iron	170-175	catalase	Homo sapiens	150-158
34475406-2	2021	Inspired by this biochemical pathway, we demonstrate the reactive oxygen species (ROS) induced tumor therapy by integrating lactate oxidase (LOx) and catalase (CAT) into Fe3O4 nanoparticle/indocyanine green (ICG) co-loaded hybrid nanogels (designated as FIGs-LC).	ferryl iron	170-175	catalase	Homo sapiens	160-163
34274779-5	2021	Under external X-ray irradiation, SnS2 cofactor as electron donor can be triggered to transfer electrons to Fe3O4, which promotes the regeneration of Fe2+ sites on the surface of the Fe3O4.	ferryl iron	108-113	sodium voltage-gated channel alpha subunit 11	Homo sapiens	34-38
34274779-5	2021	Under external X-ray irradiation, SnS2 cofactor as electron donor can be triggered to transfer electrons to Fe3O4, which promotes the regeneration of Fe2+ sites on the surface of the Fe3O4.	ferryl iron	183-188	sodium voltage-gated channel alpha subunit 11	Homo sapiens	34-38
34216673-10	2021	It is expected that the results of this study will be effective in the development of targeted drug delivery as well as the development of CS- Fe3O4-RGO-based drug carriers against various cancer cells during future research.	ferryl iron	143-148	citrate synthase	Homo sapiens	139-141
34471182-7	2021	As a result, in the case of Fe3O4@SiO2-EDG, a higher tolerance towards the FFA content can be noticed with a FAME yield of over 90% (for a 5% (weight) vs oil catalyst content) and 5% weight FFA content.	ferryl iron	28-33	benign adult familial myoclonic epilepsy 1	Homo sapiens	109-113
34559076-1	2021	An excellent magnetic multi-walled carbon nanotubes (MMWCNT) containing carboxyl material modified with ferroferric oxide (Fe3O4) nanoparticles was synthesized as the adsorbent for magnetic solid-phase extraction (MSPE) of five heavy metal ions (Pb2+, Cu2+, Co2+, Cd2+, Cr4+) in water samples followed by on-line inductively coupled plasma mass spectrometry (ICP-MS) detection.	ferryl iron	123-128	CD2 molecule	Homo sapiens	264-267
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	200-205	seryl-tRNA synthetase 1	Homo sapiens	45-49
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	200-205	H3 histone pseudogene 16	Homo sapiens	84-87
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	200-205	microRNA 21	Homo sapiens	97-105
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	235-240	seryl-tRNA synthetase 1	Homo sapiens	45-49
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	235-240	H3 histone pseudogene 16	Homo sapiens	84-87
34074418-2	2021	Herein, we reported a low cost and sensitive SERS sensing platform for simultaneous p21 mRNA and miRNA-21 detection based on duplex-specific nuclease signal amplification (DSNSA) plus multifunctional Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2 MNPs).	ferryl iron	235-240	microRNA 21	Homo sapiens	97-105
34074418-3	2021	Here, Fe3O4@SiO2 MNPs were used as a separation substrate, and Au@AgNPs served as stable and ultrasensitive SERS nanotags.	ferryl iron	6-11	seryl-tRNA synthetase 1	Homo sapiens	108-112
34074418-5	2021	Under the assistance of the target p21 mRNA and miRNA-21, DNA (CP) of the DNA-RNA heteroduplexes could be specifically degraded by DSN and the SERS nanotags that were released from the surface of Fe3O4@SiO2 MNPs.	ferryl iron	196-201	H3 histone pseudogene 16	Homo sapiens	35-38
34074418-5	2021	Under the assistance of the target p21 mRNA and miRNA-21, DNA (CP) of the DNA-RNA heteroduplexes could be specifically degraded by DSN and the SERS nanotags that were released from the surface of Fe3O4@SiO2 MNPs.	ferryl iron	196-201	microRNA 21	Homo sapiens	48-56
34074418-5	2021	Under the assistance of the target p21 mRNA and miRNA-21, DNA (CP) of the DNA-RNA heteroduplexes could be specifically degraded by DSN and the SERS nanotags that were released from the surface of Fe3O4@SiO2 MNPs.	ferryl iron	196-201	seryl-tRNA synthetase 1	Homo sapiens	143-147
34251374-5	2021	Then, an immobilization-free and label-free electrochemical platform for the determination of microRNA-21 based on Fe-N-C-thionine/Fe3O4@AuNPs was constructed.	ferryl iron	131-136	microRNA 21	Homo sapiens	94-105
34572302-0	2021	Novel Coagulation Factor VIII Gene Therapy in a Mouse Model of Hemophilia A by Lipid-Coated Fe3O4 Nanoparticles.	ferryl iron	92-97	coagulation factor VIII	Mus musculus	6-29
34575432-4	2021	Here, we report on the synthesis, physicochemical characterization, and in vitro evaluation of biocompatibility and anti-tumor activity of novel magnetically targetable SPIONs based on magnetite (Fe3O4) nanoparticles" surface modified with beta-cyclodextrin (CD) and paclitaxel (PTX)-guest-host inclusion complexes (Fe3O4@beta-CD/PTX).	ferryl iron	316-321	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	322-333
34575432-6	2021	Pristine Fe3O4@beta-CD and Fe3O4@beta-CD/PTX thin films were physicochemically characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), thermal analysis, scanning electron microscopy (SEM), and transmission electron microscopy (TEM).	ferryl iron	27-32	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	33-40
34575432-10	2021	On the other hand, Fe3O4@beta-CD/PTX films decreased the cell viability of the MG-63 osteosarcoma cell line by 85%, demonstrating excellent anti-tumor activity.	ferryl iron	19-24	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	25-36
34246058-1	2021	In the present work, three-dimensional (3D) and flower-like SnS2 materials were coated on the surface of Fe3O4@nSiO2 through an in-situ growth method.	ferryl iron	105-110	sodium voltage-gated channel alpha subunit 11	Homo sapiens	60-64
34246058-4	2021	The results showed the equilibrium of extraction and desorption towards target SAs could be reached within 3 min by using the Fe3O4@nSiO2-SnS2 composites.	ferryl iron	126-131	sodium voltage-gated channel alpha subunit 11	Homo sapiens	138-142
34246058-7	2021	Different samples including tap water, milk and honey were collected for magnetic solid-phase extraction and determination of target SAs by using the obtained Fe3O4@nSiO2-SnS2 composites to demonstrate the utility.	ferryl iron	159-164	sodium voltage-gated channel alpha subunit 11	Homo sapiens	171-175
34578493-0	2021	Synthesis of Fe3O4@mZrO2-Re (Re = Y/La/Ce) by Using Uniform Design, Surface Response Methodology, and Orthogonal Design & Its Application for As3+ and As5+ Removal.	ferryl iron	13-18	PDS5 cohesin associated factor B	Homo sapiens	142-145
34443453-0	2021	Dependence of the Nanoscale Composite Morphology of Fe3O4 Nanoparticle-Infused Lysozyme Amyloid Fibrils on Timing of Infusion: A Combined SAXS and AFM Study.	ferryl iron	52-57	lysozyme	Homo sapiens	79-87
34443453-3	2021	Using a combined solution small angle X-ray scattering (SAXS) and atomic force microscopy (AFM) approach, this study investigates the intrinsic trends of the interaction between lysozyme amyloid fibrils (LAFs) and Fe3O4 NPs before and after fibrillization at nanometer resolution.	ferryl iron	214-219	lysozyme	Homo sapiens	178-186
34368534-0	2021	Brilliant Nonlinear Optical Response of Ho3+ and Yb3+ Activated YVO4 Nanophosphor and Its Conjugation with Fe3O4 for Smart Anticounterfeit and Hyperthermia Applications.	ferryl iron	107-112	histidyl-tRNA synthetase 2, mitochondrial	Homo sapiens	40-43
34256779-15	2021	CONCLUSION: These results suggest that low doses of Fe3O4 nanoparticles combined with a SMF trigger exosomes to exert enhanced osteogenesis and angiogenesis and that targeting of HDAC7 and COL4A2 by exosomal miR-1260a plays a crucial role in this process.	ferryl iron	52-57	histone deacetylase 7	Rattus norvegicus	179-184
34299590-0	2021	Fe3O4/Graphene Composite Anode Material for Fast-Charging Li-Ion Batteries.	ferryl iron	0-5	Fas activated serine/threonine kinase	Homo sapiens	44-48
34256779-15	2021	CONCLUSION: These results suggest that low doses of Fe3O4 nanoparticles combined with a SMF trigger exosomes to exert enhanced osteogenesis and angiogenesis and that targeting of HDAC7 and COL4A2 by exosomal miR-1260a plays a crucial role in this process.	ferryl iron	52-57	collagen type IV alpha 2 chain	Rattus norvegicus	189-195
34102839-2	2021	Herein, a thrombin-responsive nanoprobe conjugated by a FITC dye, PEGylated Fe3O4 nanoparticles, and a thrombin-sensitive peptide (LASG) was constructed to visualize thrombin activation and subsequent thrombosis in vivo.	ferryl iron	76-81	coagulation factor II	Mus musculus	10-18
34105527-3	2021	Under the synergistic effect of hydrogen bonding and electrostatic adsorption, Fe3O4@PANI can rapidly and easily enrich N-glycopeptides derived from standard protein (bovine fetuin and transferrin) tryptic digests and serum haptoglobin tryptic digests.	ferryl iron	79-84	serotransferrin	Bos taurus	185-196
34105527-3	2021	Under the synergistic effect of hydrogen bonding and electrostatic adsorption, Fe3O4@PANI can rapidly and easily enrich N-glycopeptides derived from standard protein (bovine fetuin and transferrin) tryptic digests and serum haptoglobin tryptic digests.	ferryl iron	79-84	haptoglobin	Bos taurus	224-235
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	50-55	hydroxyacid oxidase 1	Homo sapiens	42-45
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	50-55	hydroxyacid oxidase 1	Homo sapiens	83-98
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	50-55	hydroxyacid oxidase 1	Homo sapiens	100-103
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	181-186	hydroxyacid oxidase 1	Homo sapiens	42-45
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	181-186	hydroxyacid oxidase 1	Homo sapiens	83-98
34137418-3	2021	Herein, a cascade catalytic nanoplatform (GOx-NCs/Fe3O4) was designed by absorbing glucose oxidase (GOx) onto the surface of covalent-assembled polymer capsules (NCs) encapsulating Fe3O4 nanoparticles.	ferryl iron	181-186	hydroxyacid oxidase 1	Homo sapiens	100-103
34105346-6	2021	The Fe3O4/PEI-PEG NGs can be further used to compact TGF-beta1 siRNA through electrostatic interaction and efficiently deliver siRNA to cancer cells and a tumor model to silence the TGF-beta1 gene, which inhibits the growth and invasion of cancer cell in vitro significantly, as well as the growth of a subcutaneous sarcoma tumor model and lung metastasis in vivo.	ferryl iron	4-9	transforming growth factor, beta 1	Mus musculus	53-62
34105346-6	2021	The Fe3O4/PEI-PEG NGs can be further used to compact TGF-beta1 siRNA through electrostatic interaction and efficiently deliver siRNA to cancer cells and a tumor model to silence the TGF-beta1 gene, which inhibits the growth and invasion of cancer cell in vitro significantly, as well as the growth of a subcutaneous sarcoma tumor model and lung metastasis in vivo.	ferryl iron	4-9	transforming growth factor, beta 1	Mus musculus	182-191
34102839-2	2021	Herein, a thrombin-responsive nanoprobe conjugated by a FITC dye, PEGylated Fe3O4 nanoparticles, and a thrombin-sensitive peptide (LASG) was constructed to visualize thrombin activation and subsequent thrombosis in vivo.	ferryl iron	76-81	coagulation factor II	Mus musculus	166-174
34102839-3	2021	The FITC dye was linked to the LASG coated on the Fe3O4 nanoparticles for sensing the thrombin activity via the Forster resonance energy transfer effect.	ferryl iron	50-55	coagulation factor II	Mus musculus	86-94
34032091-2	2021	Here, a superparamagnetic nano-Fe3O4@SiO2 functionalized material (MFS) was prepared via a co-precipitation method, and the adsorption thermodynamic and kinetic characteristics of Cd2+ were studied by isothermal adsorption tests and kinetic experiments.	ferryl iron	31-36	CD2 molecule	Homo sapiens	180-183
34189677-12	2022	The greatest gene expression changes due to the Fe2O3-NPs and Fe3O4-NPs exposure observed for HSPB1 and HSPB5, respectively.	ferryl iron	62-67	heat shock protein family B (small) member 1	Gallus gallus	94-99
34032091-10	2021	The BET, XRD, FTIR, and VSM analyses showed that SiO2 was successfully modified on the Fe3O4 surface.	ferryl iron	87-92	delta/notch like EGF repeat containing	Homo sapiens	4-7
35420609-3	2022	By integrating Fe3O4@ILI-01@Ti4+ and mass spectrometry (MS) determination, high sensitivity (0.5 fmol for beta-casein and 0.1 fmol for HRP), excellent selectivity (1 : 5000 for beta-casein : BSA and 1 : 500 for HRP : BSA, mass ratio), and high recyclability (5 cycles) were achieved.	ferryl iron	15-20	casein beta	Homo sapiens	106-117
34104122-2	2021	The objective of the current study was to design a targeted contrast agent for MRI based on Fe3O4 nanoparticles conjugated triptorelin (SPION@triptorelin), which has a great affinity to the GnRH receptors.	ferryl iron	92-97	gonadotropin releasing hormone 1	Homo sapiens	190-194
35579224-3	2022	Herein, human serum albumin (HSA)-imprinted polymer coated Fe3O4 nanoparticles (Fe3O4@MIPs) are fabricated by oxidative polymerization of dopamine in the presence of HSA on the polydopamine pre-modified Fe3O4 nanoparticle surface, followed by the removal of HSA.	ferryl iron	59-64	albumin	Homo sapiens	14-27
35579224-3	2022	Herein, human serum albumin (HSA)-imprinted polymer coated Fe3O4 nanoparticles (Fe3O4@MIPs) are fabricated by oxidative polymerization of dopamine in the presence of HSA on the polydopamine pre-modified Fe3O4 nanoparticle surface, followed by the removal of HSA.	ferryl iron	80-85	albumin	Homo sapiens	14-27
35579224-3	2022	Herein, human serum albumin (HSA)-imprinted polymer coated Fe3O4 nanoparticles (Fe3O4@MIPs) are fabricated by oxidative polymerization of dopamine in the presence of HSA on the polydopamine pre-modified Fe3O4 nanoparticle surface, followed by the removal of HSA.	ferryl iron	203-208	albumin	Homo sapiens	14-27
35104515-0	2022	Application of 3D magnetic nanocomposites: MXene-supported Fe3O4@CS nanospheres for highly efficient adsorption and separation of dyes.	ferryl iron	59-64	citrate synthase	Homo sapiens	65-67
35104515-5	2022	MXene can provide suitable support for both CS and Fe3O4 to construct new MXene@Fe3O4@CS composites.	ferryl iron	51-56	citrate synthase	Homo sapiens	86-88
35104515-5	2022	MXene can provide suitable support for both CS and Fe3O4 to construct new MXene@Fe3O4@CS composites.	ferryl iron	80-85	citrate synthase	Homo sapiens	44-46
35104515-5	2022	MXene can provide suitable support for both CS and Fe3O4 to construct new MXene@Fe3O4@CS composites.	ferryl iron	80-85	citrate synthase	Homo sapiens	86-88
35631669-9	2022	Based on our results, the synthesized theragnostic Rap/Fe3O4@VHP-Lipo serves as a great label for both MRI and fluorescence bimodal imaging of atherosclerosis.	ferryl iron	55-60	regulatory associated protein of MTOR, complex 1	Mus musculus	51-54
35182835-3	2022	In this study, surface-enhanced Raman scattering-fluorescence (SERS-FL) dual-mode nanoprobes based on Au nanoparticles modified magnetic Fe3O4 nanoparticles (Fe3O4/AuNPs) were fabricated for in situ quantification and imaging of VEGF in living cells.	ferryl iron	158-163	vascular endothelial growth factor A	Homo sapiens	229-233
35149425-4	2022	Herein, multifunctional bi-nanospheres (Fe3O4@Au NCs), which show both peroxidase-like and catalase-like catalytic activities in different working conditions, are successfully constructed and served as desirable platform with huge surface area for the immobilization of large amount of GOx probes.	ferryl iron	40-45	hydroxyacid oxidase 1	Homo sapiens	286-289
35149425-5	2022	In acidic environment, hydroxyl radicals could be generated via the cascaded catalysis of beta-d-glucose by Fe3O4@Au-GOx, and then employed to initiate the polymerization of boric acid derivative to prepare molecularly imprinted polymers (MIPs) on the surface of GOx using beta-d-glucose as template.	ferryl iron	108-113	hydroxyacid oxidase 1	Homo sapiens	117-120
35149425-5	2022	In acidic environment, hydroxyl radicals could be generated via the cascaded catalysis of beta-d-glucose by Fe3O4@Au-GOx, and then employed to initiate the polymerization of boric acid derivative to prepare molecularly imprinted polymers (MIPs) on the surface of GOx using beta-d-glucose as template.	ferryl iron	108-113	hydroxyacid oxidase 1	Homo sapiens	263-266
35149425-6	2022	Then, the molecularly imprinted GOx are immobilized on the surface of highly oriented pyrolytic graphite (HOPG) electrode and an electrochemical biosensor (Fe3O4@Au-GOx-HOPG) for glucose sensing is successfully obtained.	ferryl iron	156-161	hydroxyacid oxidase 1	Homo sapiens	32-35
35149425-6	2022	Then, the molecularly imprinted GOx are immobilized on the surface of highly oriented pyrolytic graphite (HOPG) electrode and an electrochemical biosensor (Fe3O4@Au-GOx-HOPG) for glucose sensing is successfully obtained.	ferryl iron	156-161	hydroxyacid oxidase 1	Homo sapiens	165-168
35631669-3	2022	Here, we used the targeting peptide VHPKQHR (VHP) (or fluorescent reagent) to modify the phospholipid molecules to target vascular cell adhesion molecule-1 (VCAM-1) and loaded ultrasmall paramagnetic iron oxide (USPIO/Fe3O4) plus rapamycin (Rap) to Rap/Fe3O4@VHP-Lipo (VHPKQHR-modified magnetic liposomes coated with Rap).	ferryl iron	218-223	vascular cell adhesion molecule 1	Mus musculus	122-155
35631669-3	2022	Here, we used the targeting peptide VHPKQHR (VHP) (or fluorescent reagent) to modify the phospholipid molecules to target vascular cell adhesion molecule-1 (VCAM-1) and loaded ultrasmall paramagnetic iron oxide (USPIO/Fe3O4) plus rapamycin (Rap) to Rap/Fe3O4@VHP-Lipo (VHPKQHR-modified magnetic liposomes coated with Rap).	ferryl iron	218-223	vascular cell adhesion molecule 1	Mus musculus	157-163
35631669-3	2022	Here, we used the targeting peptide VHPKQHR (VHP) (or fluorescent reagent) to modify the phospholipid molecules to target vascular cell adhesion molecule-1 (VCAM-1) and loaded ultrasmall paramagnetic iron oxide (USPIO/Fe3O4) plus rapamycin (Rap) to Rap/Fe3O4@VHP-Lipo (VHPKQHR-modified magnetic liposomes coated with Rap).	ferryl iron	253-258	vascular cell adhesion molecule 1	Mus musculus	122-155
35631669-3	2022	Here, we used the targeting peptide VHPKQHR (VHP) (or fluorescent reagent) to modify the phospholipid molecules to target vascular cell adhesion molecule-1 (VCAM-1) and loaded ultrasmall paramagnetic iron oxide (USPIO/Fe3O4) plus rapamycin (Rap) to Rap/Fe3O4@VHP-Lipo (VHPKQHR-modified magnetic liposomes coated with Rap).	ferryl iron	253-258	vascular cell adhesion molecule 1	Mus musculus	157-163
35631669-6	2022	Our results of MRI imaging and fluorescence imaging showed that the T2 relaxation time of the Rap/Fe3O4@VHP-Lipo group was reduced by 2.7 times and 1.5 times, and the fluorescence intensity increased by 3.4 times and 2.5 times, respectively, compared with the normal saline group and the control liposome treatment group.	ferryl iron	98-103	regulatory associated protein of MTOR, complex 1	Mus musculus	94-97
35631669-7	2022	It showed that Rap/Fe3O4@VHP-Lipo realized the diagnosis of early AS.	ferryl iron	19-24	regulatory associated protein of MTOR, complex 1	Mus musculus	15-18
35631669-8	2022	Additionally, our results showed that, compared with the normal saline and control liposomes treatment group, the aortic fluorescence intensity of the Rap/Fe3O4@VHP-Lipo treatment group was significantly weaker, and the T2 relaxation time was prolonged by 8.9 times and 2.0 times, indicating that the targeted diagnostic agent detected the least plaques in the Rap/Fe3O4@VHP-Lipo treatment group.	ferryl iron	155-160	regulatory associated protein of MTOR, complex 1	Mus musculus	151-154
35631669-8	2022	Additionally, our results showed that, compared with the normal saline and control liposomes treatment group, the aortic fluorescence intensity of the Rap/Fe3O4@VHP-Lipo treatment group was significantly weaker, and the T2 relaxation time was prolonged by 8.9 times and 2.0 times, indicating that the targeted diagnostic agent detected the least plaques in the Rap/Fe3O4@VHP-Lipo treatment group.	ferryl iron	155-160	regulatory associated protein of MTOR, complex 1	Mus musculus	361-364
35631669-8	2022	Additionally, our results showed that, compared with the normal saline and control liposomes treatment group, the aortic fluorescence intensity of the Rap/Fe3O4@VHP-Lipo treatment group was significantly weaker, and the T2 relaxation time was prolonged by 8.9 times and 2.0 times, indicating that the targeted diagnostic agent detected the least plaques in the Rap/Fe3O4@VHP-Lipo treatment group.	ferryl iron	365-370	regulatory associated protein of MTOR, complex 1	Mus musculus	151-154
35631669-8	2022	Additionally, our results showed that, compared with the normal saline and control liposomes treatment group, the aortic fluorescence intensity of the Rap/Fe3O4@VHP-Lipo treatment group was significantly weaker, and the T2 relaxation time was prolonged by 8.9 times and 2.0 times, indicating that the targeted diagnostic agent detected the least plaques in the Rap/Fe3O4@VHP-Lipo treatment group.	ferryl iron	365-370	regulatory associated protein of MTOR, complex 1	Mus musculus	361-364
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	131-136	troponin I3, cardiac type	Homo sapiens	43-47
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	131-136	troponin I3, cardiac type	Homo sapiens	155-159
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	131-136	troponin I3, cardiac type	Homo sapiens	206-210
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	181-186	troponin I3, cardiac type	Homo sapiens	43-47
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	181-186	troponin I3, cardiac type	Homo sapiens	155-159
35624638-2	2022	To improve the accuracy and reliability of cTnI electrochemical immunosensors, we propose a multilayer nanostructure consisting of Fe3O4-COOH labeled anti-cTnI monoclonal antibody (Fe3O4-COOH-Ab1) and anti-cTnI polyclonal antibody (Ab2) conjugated on Au-Ag nanoparticles (NPs) decorated on a metal-organic framework (Au-Ag@ZIF-67-Ab2).	ferryl iron	181-186	troponin I3, cardiac type	Homo sapiens	206-210
35624638-3	2022	In this design, Fe3O4-COOH was used for separation of cTnI in specimens and signal amplification, hierarchical porous ZIF-67 extremely enhanced the specific surface area, and Au-Ag NPs synergically promoted the conductivity and sensitivity.	ferryl iron	16-21	troponin I3, cardiac type	Homo sapiens	54-58
35403639-3	2022	Natural glucose oxidase (GOx) and superparamagnetic Fe3O4 nanoparticles have been integrated into poly(lactic-co-glycolic acid) (PLGA) to fabricate a sequential nanocatalyst (designated as GOx@PLGA-Fe3O4).	ferryl iron	52-57	hydroxyacid oxidase 1	Homo sapiens	189-192
35403639-3	2022	Natural glucose oxidase (GOx) and superparamagnetic Fe3O4 nanoparticles have been integrated into poly(lactic-co-glycolic acid) (PLGA) to fabricate a sequential nanocatalyst (designated as GOx@PLGA-Fe3O4).	ferryl iron	198-203	hydroxyacid oxidase 1	Homo sapiens	8-23
35403639-3	2022	Natural glucose oxidase (GOx) and superparamagnetic Fe3O4 nanoparticles have been integrated into poly(lactic-co-glycolic acid) (PLGA) to fabricate a sequential nanocatalyst (designated as GOx@PLGA-Fe3O4).	ferryl iron	198-203	hydroxyacid oxidase 1	Homo sapiens	25-28
35420609-3	2022	By integrating Fe3O4@ILI-01@Ti4+ and mass spectrometry (MS) determination, high sensitivity (0.5 fmol for beta-casein and 0.1 fmol for HRP), excellent selectivity (1 : 5000 for beta-casein : BSA and 1 : 500 for HRP : BSA, mass ratio), and high recyclability (5 cycles) were achieved.	ferryl iron	15-20	casein beta	Homo sapiens	177-188
35403639-3	2022	Natural glucose oxidase (GOx) and superparamagnetic Fe3O4 nanoparticles have been integrated into poly(lactic-co-glycolic acid) (PLGA) to fabricate a sequential nanocatalyst (designated as GOx@PLGA-Fe3O4).	ferryl iron	198-203	hydroxyacid oxidase 1	Homo sapiens	189-192
35420609-4	2022	In addition, Fe3O4@ILI-01@Ti4+ exhibits superior enrichment performance on synchronous enrichment of phosphopeptides/glycopeptides from beta-casein/HRP tryptic digests.	ferryl iron	13-18	casein beta	Homo sapiens	136-147
35535802-2	2022	The synthetic protocol involves the interaction between two layered inorganic compounds, ferrous hydroxide, Fe(OH)2, and the synthetic smectite LAPONITE  clay Na0.7+((Si8Mg5.5Li0.3)O20(OH)4)0.7-, towards the formation of superparamagnetic Fe3O4 nanoparticles, which are well decorated by the diamagnetic clay nanodisks.	ferryl iron	239-244	general transcription factor IIE subunit 1	Homo sapiens	108-115
35624582-4	2022	Therefore, we designed an ultracentrifugation-free and antibody-free sensing assay for PD-L1@EV by integrating Titanium oxide (TiO2) coated magnetic beads (Fe3O4@TiO2) rapid capturing of EVs from undiluted serum with aptamers specificity and chemiluminescence (CL) sensitivity.	ferryl iron	156-161	CD274 molecule	Homo sapiens	87-92
35044605-1	2022	The purpose of this investigation was to analyze the performance of magnetite graphene oxide modified with beta-cyclodextrin (GO@Fe3O4@beta-CD) for adsorption of methotrexate (MTX) and doxorubicin (DOX) from aqueous solutions.	ferryl iron	129-134	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	135-142
35044605-2	2022	Characterization of GO@Fe3O4@beta-CD was carried out using some methods.	ferryl iron	23-28	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	29-36
35044605-4	2022	The adsorption kinetic of MTX and DOX via GO@Fe3O4@beta-CD followed pseudo second-order (PSO) model, while the adsorption isotherm obeyed Langmuir model by monolayer adsorption with maximum adsorption capacities of 198.5 and 204.5 mg g-1 for MTX and DOX, respectively.	ferryl iron	45-50	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	51-58
35044605-5	2022	Therefore, it could be argued that HCl and 0.1 mol L-1 NaOH would reflect adequate elution properties for GO@Fe3O4@beta-CD recovery.	ferryl iron	109-114	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	115-122
35121542-1	2022	An ultrasensitive electrochemical detection of the activity and inhibition of T4 polynucleotide kinase (T4 PNK) was developed by using magnetic Fe3O4@TiO2 core-shell nanoparticles, which was triggered by a rolling circle amplification strategy (Fe3O4@TiO2-RCA).	ferryl iron	144-149	polynucleotide kinase 3'-phosphatase	Homo sapiens	107-110
35121542-1	2022	An ultrasensitive electrochemical detection of the activity and inhibition of T4 polynucleotide kinase (T4 PNK) was developed by using magnetic Fe3O4@TiO2 core-shell nanoparticles, which was triggered by a rolling circle amplification strategy (Fe3O4@TiO2-RCA).	ferryl iron	245-250	polynucleotide kinase 3'-phosphatase	Homo sapiens	107-110
35615314-6	2022	Meanwhile, exposure to Fe3O4/GO nanomaterials increased reactive oxygen species (ROS) levels, calcium ions levels, and oxidative stress in mitochondria produced by these nanomaterials activated Caspase-9 and Caspase-3, ultimately leading to cell apoptosis.	ferryl iron	23-28	caspase 9	Homo sapiens	194-203
35615314-6	2022	Meanwhile, exposure to Fe3O4/GO nanomaterials increased reactive oxygen species (ROS) levels, calcium ions levels, and oxidative stress in mitochondria produced by these nanomaterials activated Caspase-9 and Caspase-3, ultimately leading to cell apoptosis.	ferryl iron	23-28	caspase 3	Homo sapiens	208-217
35473528-3	2022	Objective:In this study, we proposed to construct high expression of Ferroportin1 macrophages as carriers to deliver Fe3O4-nanoparticles and iron directly to tumor sites.	ferryl iron	117-122	solute carrier family 40 (iron-regulated transporter), member 1	Mus musculus	69-81
35473528-7	2022	Fe3O4-NPs in Ana-1 cells were degraded in lysosomes, and the amount of iron released was correlated with the expression of ferroportin1.	ferryl iron	0-5	solute carrier family 40 (iron-regulated transporter), member 1	Mus musculus	123-135
35473528-13	2022	Moreover, increase of intracellular iron efflux by overexpression of FPN1, cell carriers can act as a reservoir for iron, providing the basis for targeted delivery of Fe3O4-NPs and iron ions in vivo.	ferryl iron	167-172	solute carrier family 40 (iron-regulated transporter), member 1	Mus musculus	69-73
35557658-2	2022	The silica-coated MNPs functionalized with the Cu(*II)-mesalamine complex was (Fe3O4@SiO2@NH2-TCT-mesalamine-Cu(II) MNPs) completely characterized by FT-IR, XRD, EDX, FESEM, TEM, VSM, TGA, and BET analyses.	ferryl iron	79-84	T-box transcription factor 1	Homo sapiens	184-187
35479105-0	2022	Diverse and efficient catalytic applications of new cockscomb flower-like Fe3O4@SiO2@KCC-1@MPTMS@CuII mesoporous nanocomposite in the environmentally benign reduction and reductive acetylation of nitroarenes and one-pot synthesis of some coumarin compounds.	ferryl iron	74-79	solute carrier family 12 member 4	Homo sapiens	85-90
35557658-2	2022	The silica-coated MNPs functionalized with the Cu(*II)-mesalamine complex was (Fe3O4@SiO2@NH2-TCT-mesalamine-Cu(II) MNPs) completely characterized by FT-IR, XRD, EDX, FESEM, TEM, VSM, TGA, and BET analyses.	ferryl iron	79-84	delta/notch like EGF repeat containing	Homo sapiens	193-196
35366904-6	2022	Our study further confirmed that ferroptosis was involved in the anti-tumor process of ADM/Fe3O4-MS plus microwave irradiation, and ferroptosis marker GPX4 was significantly decreased and ACSL4 was significantly increased, and ferroptosis inhibitors could reverse the tumor cell killing effect caused by ADM/Fe3O4-MS to a certain extent.	ferryl iron	91-96	glutathione peroxidase 4	Homo sapiens	151-155
35315859-3	2022	The peroxidase activity enhances the intensity of the brownish coloring of the Fe3O4@Pt probes on the test strip, with a limit of detection of 10 pg mL-1 using the naked eye, which is remarkable for colorimetric lateral flow assays.	ferryl iron	79-84	L1 cell adhesion molecule	Mus musculus	149-153
35366904-6	2022	Our study further confirmed that ferroptosis was involved in the anti-tumor process of ADM/Fe3O4-MS plus microwave irradiation, and ferroptosis marker GPX4 was significantly decreased and ACSL4 was significantly increased, and ferroptosis inhibitors could reverse the tumor cell killing effect caused by ADM/Fe3O4-MS to a certain extent.	ferryl iron	91-96	acyl-CoA synthetase long chain family member 4	Homo sapiens	188-193
35197099-0	2022	Sensitive and selective detection of Mucin1 in pancreatic cancer using hybridization chain reaction with the assistance of Fe3O4@polydopamine nanocomposites.	ferryl iron	123-128	mucin 1, cell surface associated	Homo sapiens	37-43
35168125-1	2022	In this study, a novel polydopamine and C18 dual-functionalized magnetic core-shell mesoporous silica (Fe3O4@nSiO2@mSiO2@PDA-C18) nanocomposite was designed and synthesized, which was employed as an adsorbent to extract illegal drugs from urine samples by magnetic solid-phase extraction (MSPE) procedures.	ferryl iron	103-108	Bardet-Biedl syndrome 9	Homo sapiens	40-43
35168125-1	2022	In this study, a novel polydopamine and C18 dual-functionalized magnetic core-shell mesoporous silica (Fe3O4@nSiO2@mSiO2@PDA-C18) nanocomposite was designed and synthesized, which was employed as an adsorbent to extract illegal drugs from urine samples by magnetic solid-phase extraction (MSPE) procedures.	ferryl iron	103-108	Bardet-Biedl syndrome 9	Homo sapiens	125-128
35244662-3	2022	Owing to its strong magnetic property, large surface area (845 m2 g-1), excellent hydrophilicity and suitable porous structure, the GO@Fe3O4@MOF-303 probe exhibits an ultralow detection limit (0.1 fmol muL-1), perfect size-exclusion effect (HRP digests/BSA protein/HRP protein, 1 : 1000 : 1000, w/w/w), a high binding capacity (200 mg g-1) and excellent reusability in the capture of standard N-linked glycopeptides.	ferryl iron	135-140	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	202-207
35137583-5	2022	When integrated with the dual-antibody sandwich LFIA platform, the developed Fe3O4@MOF@Pt can achieve an ultrasensitive immunochromatographic assay of procalcitonin with a sensitivity of 0.5 pg mL-1, which is approximately 2280-fold higher than that of conventional AuNP-based LFIA and superior to previously published immunoassays.	ferryl iron	77-82	L1 cell adhesion molecule	Mus musculus	194-198
35331259-4	2022	In the present study, we developed a tumor "cruise missile", mesoporous Fe3O4-containing glucose oxidase-conjugated GPC3 peptide nanoparticles (FGP NPs).	ferryl iron	72-77	glypican 3	Mus musculus	116-120
35200395-2	2022	In this work, magnetic graphene oxide (Fe3O4@GO, MGO) was applied to immobilize diamine oxidase (DAO) through a method of adsorption and covalent bonding.	ferryl iron	39-44	amine oxidase copper containing 1	Homo sapiens	80-95
35200395-2	2022	In this work, magnetic graphene oxide (Fe3O4@GO, MGO) was applied to immobilize diamine oxidase (DAO) through a method of adsorption and covalent bonding.	ferryl iron	39-44	amine oxidase copper containing 1	Homo sapiens	97-100
35104098-4	2022	Herein, we propose simple, low-cost, dual-aptamer (EpCAM and PTK7)-modified immunomagnetic Fe3O4 particles (IMNs) for efficient capture of heterogeneous CTCs and downstream analysis in gastric cancer patients.	ferryl iron	91-96	epithelial cell adhesion molecule	Homo sapiens	51-56
35104098-4	2022	Herein, we propose simple, low-cost, dual-aptamer (EpCAM and PTK7)-modified immunomagnetic Fe3O4 particles (IMNs) for efficient capture of heterogeneous CTCs and downstream analysis in gastric cancer patients.	ferryl iron	91-96	protein tyrosine kinase 7 (inactive)	Homo sapiens	61-65
35045701-4	2022	The Fc aptamer was intentionally used to capture the Tie1 through its Fc tag, connecting with Fe3O4-coated silver magnetic nanoparticles (Ag@MNPs) and ensuring the LECT2 binding site to be outward.	ferryl iron	94-99	tyrosine kinase with immunoglobulin like and EGF like domains 1	Homo sapiens	53-57
35044388-5	2022	In detail, benefiting from the internal synergistic effect of Fe3O4 NPs and Au NPs and external NIR-mediated hyperthermia, the BFA NPs can boost hydroxyl radical ( OH) generation to enhance intracellular oxidative stress and further induce ferroptosis by inactivating glutathione peroxidase 4 (GPX4).	ferryl iron	62-67	glutathione peroxidase 4	Homo sapiens	268-292
35044388-5	2022	In detail, benefiting from the internal synergistic effect of Fe3O4 NPs and Au NPs and external NIR-mediated hyperthermia, the BFA NPs can boost hydroxyl radical ( OH) generation to enhance intracellular oxidative stress and further induce ferroptosis by inactivating glutathione peroxidase 4 (GPX4).	ferryl iron	62-67	glutathione peroxidase 4	Homo sapiens	294-298
35174172-1	2021	Objectives: Tumor cells were reported to have perpetual negative surface charges due to elevated glycolysis, and multifunctional nanoprobes (Fe3O4@SiO2, mNPs) could attach onto tumor cells via opposite surface charges.	ferryl iron	141-146	neuropeptide S	Mus musculus	153-157
35225464-5	2022	By co-encapsulation of Met and Sil into PLGA/PEG/ Fe3O4, cytotoxic efficiency of the compounds considerably augmented for all concentrations.	ferryl iron	50-55	SAFB like transcription modulator	Homo sapiens	23-26
35225464-7	2022	Moreover, qPCR data revealed that the expression levels of the leptin and leptin receptor was considerably reduced with increasing concentrations of drug-encapsulated magnetic NPs, especially Met/Sil-encapsulated PLGA/PEG/ Fe3O4 NPs.	ferryl iron	223-228	leptin	Homo sapiens	63-69
35225464-7	2022	Moreover, qPCR data revealed that the expression levels of the leptin and leptin receptor was considerably reduced with increasing concentrations of drug-encapsulated magnetic NPs, especially Met/Sil-encapsulated PLGA/PEG/ Fe3O4 NPs.	ferryl iron	223-228	leptin receptor	Homo sapiens	74-89
35225464-7	2022	Moreover, qPCR data revealed that the expression levels of the leptin and leptin receptor was considerably reduced with increasing concentrations of drug-encapsulated magnetic NPs, especially Met/Sil-encapsulated PLGA/PEG/ Fe3O4 NPs.	ferryl iron	223-228	SAFB like transcription modulator	Homo sapiens	192-195
35023716-4	2022	In the presence of As(V), S1 could be released based on the stronger affinity between As(V) and Co3O4-Fe3O4 cubes.	ferryl iron	102-107	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	19-24
35091896-3	2022	The magnetic Fe3O4@Agar-Ag nanocatalyst was characterized thoroughly by FT-IR, XRD, SEM, TEM, VSM, EDX, TGA, and ICP analyses.	ferryl iron	13-18	T-box transcription factor 1	Homo sapiens	104-107
35127195-0	2022	A Colorimetric Immunoassay Based on g-C3N4@Fe3O4 Nanocomposite for Detection of Carcinoembryonic Antigen.	ferryl iron	43-48	CEA cell adhesion molecule 3	Homo sapiens	80-104
35127195-1	2022	We proposed a colorimetric immunosensor based on g-C3N4@Fe3O4 nanocomposite-mediated transformation strategy for sensitive detection of carcinoembryonic antigen (CEA).	ferryl iron	56-61	CEA cell adhesion molecule 3	Homo sapiens	136-160
35127195-1	2022	We proposed a colorimetric immunosensor based on g-C3N4@Fe3O4 nanocomposite-mediated transformation strategy for sensitive detection of carcinoembryonic antigen (CEA).	ferryl iron	56-61	CEA cell adhesion molecule 3	Homo sapiens	162-165
35023716-4	2022	In the presence of As(V), S1 could be released based on the stronger affinity between As(V) and Co3O4-Fe3O4 cubes.	ferryl iron	102-107	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	86-91
35023716-10	2022	Interestingly, As(V) was also simultaneously separated from the detection system by Co3O4-Fe3O4 magnetic cubes.	ferryl iron	90-95	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	15-20
35056754-4	2022	The monodisperse MNPs were incorporated into the crosslinked PIL (CQVP-MA) by ultrasonication to prepare CQVP-MA/Fe3O4 composite to facilitate its recovery using an external magnetic field and enhance its adsorption capacity.	ferryl iron	113-118	serpin family A member 2 (gene/pseudogene)	Homo sapiens	61-64
35215251-4	2022	Subsequently, the layer-by-layer (LbL) assembly of iron oxide nanoparticles (Fe3O4) and betanin can provide the conjugation of 1-methyl-D-tryptophan (1-M-DT) on the nanoparticle to form an NO gas-photothermal-immune nano-platform (GAPFBD) for achieving combinatory therapy of NO gas, photothermal therapy (PTT), and indoleamine 2,3-dioxygenase (IDO) immunotherapy.	ferryl iron	77-82	indoleamine 2,3-dioxygenase 1	Homo sapiens	316-343
35215251-4	2022	Subsequently, the layer-by-layer (LbL) assembly of iron oxide nanoparticles (Fe3O4) and betanin can provide the conjugation of 1-methyl-D-tryptophan (1-M-DT) on the nanoparticle to form an NO gas-photothermal-immune nano-platform (GAPFBD) for achieving combinatory therapy of NO gas, photothermal therapy (PTT), and indoleamine 2,3-dioxygenase (IDO) immunotherapy.	ferryl iron	77-82	indoleamine 2,3-dioxygenase 1	Homo sapiens	345-348
35056754-6	2022	Adsorption kinetics, isotherms, and mechanisms of CB-R250 elimination from aqueous solutions using CQVP-MA and CQVP-MA/Fe3O4 were also studied, and the results revealed that the pseudo second-order kinetic model and the Langmuir isotherm model were the most suitable to describe the CBB adsorption from an aqueous solution.	ferryl iron	119-124	cannabinoid receptor 1	Homo sapiens	50-54
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	hydroxyacid oxidase 1, liver	Mus musculus	10-13
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	hydroxyacid oxidase 1, liver	Mus musculus	34-49
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	hydroxyacid oxidase 1, liver	Mus musculus	51-54
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	catalase	Mus musculus	57-65
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	catalase	Mus musculus	67-70
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	hydroxyacid oxidase 1, liver	Mus musculus	159-162
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	hydroxyacid oxidase 1, liver	Mus musculus	171-174
34983560-4	2022	The Fe3O4-GOx possesses intrinsic glucose oxidase (GOx), catalase (CAT) and peroxidase (POD)-like activities, and can catalyze pH-switchable glucose-initiated GOx/POD and GOx/CAT cascade reaction in acidic and neutral environment, respectively.	ferryl iron	4-9	catalase	Mus musculus	175-178
34983560-8	2022	Remarkably, this Fe3O4-GOx-instructed spatial-temporal remodeling of DU microenvironment enables complete re-epithelialization of biofilm-infected wound in diabetic mice within 15 days while minimizing toxicity to normal tissues, exerting great transformation potential in clinical DU management.	ferryl iron	17-22	hydroxyacid oxidase 1, liver	Mus musculus	23-26
33934761-0	2021	Preparation of GO/Fe3O4@PMDA/AuNPs nanocomposite for simultaneous determination of As3+ and Cu2+ by stripping voltammetry.	ferryl iron	18-23	PDS5 cohesin associated factor B	Homo sapiens	83-86
33965019-4	2021	Detailed characteristics of Fe3O4@COF-TpTAM were evaluated via various techniques including TEM, FTIR, TGA, XRD and BET.	ferryl iron	28-33	T-box transcription factor 1	Homo sapiens	103-106
33965019-4	2021	Detailed characteristics of Fe3O4@COF-TpTAM were evaluated via various techniques including TEM, FTIR, TGA, XRD and BET.	ferryl iron	28-33	delta/notch like EGF repeat containing	Homo sapiens	116-119
33714116-1	2021	Fe3O4 magnetic nanoparticles modified with tetraethyl orthosilicate and bovine serum albumin (Fe3O4@TEOS@BSA) were synthesized and efficiently used to separate lysozyme from egg white.	ferryl iron	0-5	albumin	Gallus gallus	79-92
33714116-1	2021	Fe3O4 magnetic nanoparticles modified with tetraethyl orthosilicate and bovine serum albumin (Fe3O4@TEOS@BSA) were synthesized and efficiently used to separate lysozyme from egg white.	ferryl iron	94-99	albumin	Gallus gallus	79-92
33934761-6	2021	The GCE/GO/Fe3O4@PMDA/AuNPs also has good linearity over a wide concentration range from 5 to 500 ppb for As3+ and 0.5-750 ppb for Cu2+.	ferryl iron	11-16	PDS5 cohesin associated factor B	Homo sapiens	106-109
33838769-4	2021	After their efficiency was proven, these materials were used as modifiers in the electrochemical sensor (Fe3O4@MIP-GO/CPE).	ferryl iron	105-110	carboxypeptidase E	Homo sapiens	118-121
33524653-3	2021	Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1.	ferryl iron	43-48	L1 cell adhesion molecule	Mus musculus	229-233
33524653-3	2021	Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1.	ferryl iron	43-48	L1 cell adhesion molecule	Mus musculus	263-267
33524653-3	2021	Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1.	ferryl iron	43-48	L1 cell adhesion molecule	Mus musculus	263-267
34019763-8	2021	Then, hepatitis B virus (HBV) and p53 gene were detected by this proposed method through introducing the Fe3O4 nanoparticles into the gene hybridization system.	ferryl iron	105-110	tumor protein p53	Homo sapiens	34-37
34008694-0	2021	Dual-recognition colorimetric sensing of thrombin based on surface-imprinted aptamer-Fe3O4.	ferryl iron	85-90	coagulation factor II, thrombin	Homo sapiens	41-49
34008694-3	2021	Herein, surface molecularly imprinted polymer (MIP) was modified on aptamer-functionalized Fe3O4 nanoparticles (MIP-aptamer-Fe3O4 NP) for thrombin colorimetric assay by taking advantage of the peroxidase-like activity of Fe3O4 NP.	ferryl iron	91-96	coagulation factor II, thrombin	Homo sapiens	138-146
34008694-3	2021	Herein, surface molecularly imprinted polymer (MIP) was modified on aptamer-functionalized Fe3O4 nanoparticles (MIP-aptamer-Fe3O4 NP) for thrombin colorimetric assay by taking advantage of the peroxidase-like activity of Fe3O4 NP.	ferryl iron	124-129	coagulation factor II, thrombin	Homo sapiens	138-146
34008694-3	2021	Herein, surface molecularly imprinted polymer (MIP) was modified on aptamer-functionalized Fe3O4 nanoparticles (MIP-aptamer-Fe3O4 NP) for thrombin colorimetric assay by taking advantage of the peroxidase-like activity of Fe3O4 NP.	ferryl iron	124-129	coagulation factor II, thrombin	Homo sapiens	138-146
34040372-6	2021	Methods: The nanocomposite Ca5(PO4)3OH/Fe3O4 (later called nHAp/IO) was obtained by the wet chemistry method and functionalised with microRNAs (nHAp/IO@miR-21/124).	ferryl iron	39-44	microRNA 21a	Mus musculus	152-158
33881052-3	2021	GOx on the surface of hollow mesoporous silica nanoparticles can catalyze the decomposition of intratumoral glucose to generate gluconic acid and H2O2, while Fe3O4 nanoparticles as a Fenton reaction catalyst can in situ catalyze H2O2 to produce highly toxic hydroxyl radicals ( OH).	ferryl iron	158-163	hydroxyacid oxidase 1	Homo sapiens	0-3
34022705-2	2021	For alpha-glucosidase immobilization, magnetic core-shell metal-organic frameworks composite (Fe3O4@CS@ZIF-8) was fabricated by a step-by-step assembly method, and alpha-glucosidase was in situ encapsulated in crystal lattice of ZIF-8.	ferryl iron	94-99	sucrase-isomaltase	Homo sapiens	4-21
33998609-3	2021	In this work, we developed a nano-capturer Fe3O4@SiO2-NTA with an enhanced signal by taking advantage of a AuNP-anti-IgE nanobioprobe for precise and highly sensitive quantification detection of sIgE in serum of allergic patients.	ferryl iron	43-48	immunoglobulin heavy constant epsilon	Homo sapiens	117-120
33998609-5	2021	Numerous horseradish peroxidase (HRP)-labeled anti-IgE were modified onto one AuNP to detect the sIgE probed by Fe3O4@SiO2-NTA@rCanf1.	ferryl iron	112-117	immunoglobulin heavy constant epsilon	Homo sapiens	51-54
34022705-2	2021	For alpha-glucosidase immobilization, magnetic core-shell metal-organic frameworks composite (Fe3O4@CS@ZIF-8) was fabricated by a step-by-step assembly method, and alpha-glucosidase was in situ encapsulated in crystal lattice of ZIF-8.	ferryl iron	94-99	sucrase-isomaltase	Homo sapiens	164-181
33548613-8	2021	Moreover, owing to the photothermal effect of the Fe3O4 NPs, the coating"s surface temperature can be rapidly increased above 0  C under infrared irradiation, which facilitates the ice melting on cold surfaces.	ferryl iron	50-55	carboxylesterase 2	Homo sapiens	181-184
34004477-7	2021	We further observed the disrupted cystine/glutamate reverse transporter (System Xc-) and glutathione peroxidase 4 (GPX4) signaling in gamma-Fe2O3 and Fe3O4 NPs-challenged HUVECs.	ferryl iron	150-155	glutathione peroxidase 4	Homo sapiens	89-113
34004477-7	2021	We further observed the disrupted cystine/glutamate reverse transporter (System Xc-) and glutathione peroxidase 4 (GPX4) signaling in gamma-Fe2O3 and Fe3O4 NPs-challenged HUVECs.	ferryl iron	150-155	glutathione peroxidase 4	Homo sapiens	115-119
34004477-8	2021	gamma-Fe2O3 and Fe3O4 NPs could also cause mitochondrial fusion and fission dysregulation, activate lipid peroxidation and iron metabolism-related genes in a P53-dependent manner.	ferryl iron	16-21	tumor protein p53	Homo sapiens	158-161
33881837-4	2021	After loaded with l-arginine (l-Arg) and sealed with poly(acrylic acid) (PAA), hollow Fe3O4 NPs were fabricated into LPFe3O4 NPs, which could release l-Arg based on pH-responsive PAA and produce nitric oxide (NO) with the help of nitric oxide synthase (iNOS) overexpressed by M1 TAMs, as a result of additional tumor elimination for gas therapy.	ferryl iron	86-91	nitric oxide synthase 2	Homo sapiens	253-257
34007177-11	2021	Fe3O4@PDA-labeled MSCs decreased spinal nerve demyelination and c-Fos expression (a pain molecule); moreover, they inhibited microglia and astrocyte activation.	ferryl iron	0-5	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	64-69
33676681-4	2021	The Fe3O4@SiO2-NH2-Au@Pd0.30NPs-protG exhibited a high binding affinity for the captured anti-p53aAbs and high catalytic performance towards the oxidation of 3,3",5,5"-tetramethylbenzidine (TMB).	ferryl iron	4-9	tumor protein p53	Homo sapiens	94-97
33676694-5	2021	Thanks to the recognition sites of phosphate and the template-shaped cavities, Fe3O4@TiO2@Lys MIPs showed great sensitivity (0.01 ng*muL-1) and selectivity (Lysozyme: BSA: beta-casein = 1:100:100, mass ratio) in standard phosphoprotein solution.	ferryl iron	79-84	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	133-138
33676694-5	2021	Thanks to the recognition sites of phosphate and the template-shaped cavities, Fe3O4@TiO2@Lys MIPs showed great sensitivity (0.01 ng*muL-1) and selectivity (Lysozyme: BSA: beta-casein = 1:100:100, mass ratio) in standard phosphoprotein solution.	ferryl iron	79-84	lysozyme	Homo sapiens	157-165
33676681-7	2021	The apparent binding affinity (KD) between the p53aAbs and Fe3O4@SiO2-NH2-Au@Pd0.30NPs-protG was 35.2 ng mL-1.	ferryl iron	59-64	tumor protein p53	Homo sapiens	47-50
33676694-6	2021	At the end, the Fe3O4@TiO2@Lys MIPs showed great separation ability to lysozyme phosphoprotein in both human serum and urine samples.	ferryl iron	16-21	lysozyme	Homo sapiens	71-79
33676681-7	2021	The apparent binding affinity (KD) between the p53aAbs and Fe3O4@SiO2-NH2-Au@Pd0.30NPs-protG was 35.2 ng mL-1.	ferryl iron	59-64	L1 cell adhesion molecule	Mus musculus	105-109
33878477-12	2021	In the present study, we fabricated multifunctional core-shell-corona nanohybrids (Fe3O4@PDA@anti-miRNA/DNA) to simultaneously perform on-demand photothermal therapy, miR-21-triggered chemotherapy, and miR-21-dependent gene therapy at the same location, which can achieve an efficient synergistic effect for precise and effective tumor treatment.	ferryl iron	83-88	microRNA 21a	Mus musculus	167-173
34007509-1	2021	This work reveals the As(V) adsorption behaviors onto iron oxide (Fe3O4) nanoparticles modified activated carbon (AC), originally developed from biochar (BC), as a green adsorbent denoted by FAC.	ferryl iron	66-71	FA complementation group C	Homo sapiens	191-194
33996766-7	2021	Pathogens were enriched by Fc-MBL@Fe3O4 from briefly pre-cultured liquid media and identified by MALDI-TOF MS. We identified an opportunistic pathogen, Vibrio alginolyticus, which is uncommon in clinical orthopedic trauma infection but exists widely in the sea.	ferryl iron	34-39	mannose-binding lectin family member 3, pseudogene	Homo sapiens	30-33
33996766-8	2021	Therefore, combining Fc-MBL@Fe3O4 enrichment and MALDI-TOF MS profiling has great potential for direct identification of microbes in clinical samples.	ferryl iron	28-33	mannose-binding lectin family member 3, pseudogene	Homo sapiens	24-27
33878477-12	2021	In the present study, we fabricated multifunctional core-shell-corona nanohybrids (Fe3O4@PDA@anti-miRNA/DNA) to simultaneously perform on-demand photothermal therapy, miR-21-triggered chemotherapy, and miR-21-dependent gene therapy at the same location, which can achieve an efficient synergistic effect for precise and effective tumor treatment.	ferryl iron	83-88	microRNA 21a	Mus musculus	202-208
33923696-2	2021	Under the induction of a magnetic field, it can be orientated in an epoxy resin (EP) matrix, thus preparing EP/GR-Fe3O4 composites.	ferryl iron	114-119	epiregulin	Homo sapiens	81-83
33923696-2	2021	Under the induction of a magnetic field, it can be orientated in an epoxy resin (EP) matrix, thus preparing EP/GR-Fe3O4 composites.	ferryl iron	114-119	epiregulin	Homo sapiens	108-113
33923696-4	2021	When the mass ratio of GR and Fe3O4 was 2:1, the thermal conductivity could be increased by 54.8% compared with that of pure EP.	ferryl iron	30-35	epiregulin	Homo sapiens	125-127
33923696-5	2021	Meanwhile, EP/GR-Fe3O4 composites had a better thermal stability, dynamic thermomechanical properties, and excellent electrical insulation properties, which can meet the requirements of electronic packaging materials.	ferryl iron	17-22	epiregulin	Homo sapiens	11-16
33924693-4	2021	In this study, a novel strategy based on ligand-receptor interactions to discover novel PLA2 inhibitors was established, in which PLA2-functionalized Fe3O4@PLGA-PEG-NH2 magnetic nanoparticles were used as a supporting material combined with high-performance liquid chromatography-mass spectrometry, aiming to accelerate the discovery of novel PLA2 inhibitors from natural sources such as mangrove endophytic fungi.	ferryl iron	150-155	phospholipase A2 group IB	Homo sapiens	88-92
33924693-4	2021	In this study, a novel strategy based on ligand-receptor interactions to discover novel PLA2 inhibitors was established, in which PLA2-functionalized Fe3O4@PLGA-PEG-NH2 magnetic nanoparticles were used as a supporting material combined with high-performance liquid chromatography-mass spectrometry, aiming to accelerate the discovery of novel PLA2 inhibitors from natural sources such as mangrove endophytic fungi.	ferryl iron	150-155	phospholipase A2 group IB	Homo sapiens	130-134
33924693-4	2021	In this study, a novel strategy based on ligand-receptor interactions to discover novel PLA2 inhibitors was established, in which PLA2-functionalized Fe3O4@PLGA-PEG-NH2 magnetic nanoparticles were used as a supporting material combined with high-performance liquid chromatography-mass spectrometry, aiming to accelerate the discovery of novel PLA2 inhibitors from natural sources such as mangrove endophytic fungi.	ferryl iron	150-155	phospholipase A2 group IB	Homo sapiens	130-134
33924693-7	2021	In conclusion, PLA2-functionalized Fe3O4@PLGA-PEG-NH2 magnetic nanoparticles-based ligand fishing provided a feasible, selective and effective platform for the efficient screening and identification of antitumor components from natural products.	ferryl iron	35-40	phospholipase A2 group IB	Homo sapiens	15-19
33785350-4	2021	Fe3O4@T7/AS1411/DTX&SKN-M is capable of stably circulating in the blood, accumulating around the brain under an external magnetic field, distributing inside the glioma via the affinity to nucleolin/transferrin receptor, and retarding the growth of orthotopic glioma.	ferryl iron	0-5	nucleolin	Mus musculus	188-197
33283373-3	2021	Herein, we report an Fe3O4 nanoparticle-based glutathione (GSH) responsive magnetic resonance imaging (MRI) probe that can form particle aggregates within tumors in vivo to give rise to strong GSH concentration dependent interlocked relaxivities (R1 and R2).	ferryl iron	21-26	CD1b molecule	Homo sapiens	247-256
31543028-2	2021	The maximum adsorption capacity of Co(II) onto Fe3O4@CS-EDTA was 48.78 mg/g at pH = 5 (303 K), which is much higher than that of Fe3O4@Chitosan as well as chitosan.	ferryl iron	129-134	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	35-41
31543028-3	2021	The kinetics of Co(II) on the Fe3O4@CS-EDTA was consistent with the pseudo-second-order model.	ferryl iron	30-35	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	16-22
31543028-6	2021	Furthermore, after four cycles, the adsorption capacity of Co(II) onto the Fe3O4@CS-EDTA still retained 84.5% of the capacity of the fresh adsorbent, indicating that Fe3O4@CS-EDTA can be considered a promising recyclable adsorbent to remove heavy-metal ions from wastewater.	ferryl iron	75-80	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	59-65
31543028-6	2021	Furthermore, after four cycles, the adsorption capacity of Co(II) onto the Fe3O4@CS-EDTA still retained 84.5% of the capacity of the fresh adsorbent, indicating that Fe3O4@CS-EDTA can be considered a promising recyclable adsorbent to remove heavy-metal ions from wastewater.	ferryl iron	166-171	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	59-65
31543028-1	2021	In this study, an efficient adsorption and reusable magnetic ligand material (Fe3O4@Chitosan-EDTA) was synthesized by binding EDTA dianhydride onto magnetic chitosan, and it was employed in removal of Co(II) from aqueous solution.	ferryl iron	78-83	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	201-207
31543028-2	2021	The maximum adsorption capacity of Co(II) onto Fe3O4@CS-EDTA was 48.78 mg/g at pH = 5 (303 K), which is much higher than that of Fe3O4@Chitosan as well as chitosan.	ferryl iron	47-52	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	35-41
33785350-4	2021	Fe3O4@T7/AS1411/DTX&SKN-M is capable of stably circulating in the blood, accumulating around the brain under an external magnetic field, distributing inside the glioma via the affinity to nucleolin/transferrin receptor, and retarding the growth of orthotopic glioma.	ferryl iron	0-5	transferrin receptor	Mus musculus	198-218
33743019-3	2021	With the electroactive surface area is 1.7 times higher than that of bare SPAuE, the rGO/DWCNTs/Oct-Fe3O4/Cs/SPAuE for detection of GLY shows a low detection limit (LOD) of ~ 0.08 ppb in a large concentration range of 0.1-1000 ppb.	ferryl iron	100-105	plexin A2	Homo sapiens	96-99
33707945-2	2021	Methods: In this study, a novel SERS-based sandwich immunoassay, which consists of tannin-capped silver nanoparticles and magnetic graphene oxide (Fe3O4@GOs), was developed.	ferryl iron	147-152	seryl-tRNA synthetase 1	Homo sapiens	32-36
33791142-1	2021	A fast method based on Fe3O4 magnetic nanoparticles (Fe3O4 MNPs) modified QuEChERS integrated to dispersive liquid-liquid microextraction (DLLME) coupled with gas chromatography-mass spectrometry was established for the determination of 8 organochlorine pesticides (OCPs) in green leafy vegetables.	ferryl iron	23-28	gastrin	Homo sapiens	159-162
33635047-4	2021	The adsorption performance of Fe3O4@PMAA@Ni microspheres for His-proteins was estimated via selectively separating bovine hemoglobin (BHb) and bovine serum albumin (BSA) from a matrix composed of BHb, BSA, and lysozyme (LYZ).	ferryl iron	30-35	albumin	Bos taurus	150-163
33635047-4	2021	The adsorption performance of Fe3O4@PMAA@Ni microspheres for His-proteins was estimated via selectively separating bovine hemoglobin (BHb) and bovine serum albumin (BSA) from a matrix composed of BHb, BSA, and lysozyme (LYZ).	ferryl iron	30-35	lysozyme C, tracheal isozyme	Bos taurus	210-218
33635047-4	2021	The adsorption performance of Fe3O4@PMAA@Ni microspheres for His-proteins was estimated via selectively separating bovine hemoglobin (BHb) and bovine serum albumin (BSA) from a matrix composed of BHb, BSA, and lysozyme (LYZ).	ferryl iron	30-35	lysozyme C, tracheal isozyme	Bos taurus	220-223
33624188-0	2021	EGFR-specific single-chain variable fragment antibody-conjugated Fe3O4/Au nanoparticles as an active MRI contrast agent for NSCLC.	ferryl iron	65-70	epidermal growth factor receptor	Mus musculus	0-4
33321280-3	2021	The as-prepared photocatalyst was characterized by XRD, VSM, BET, FTIR, FE-SEM, UV-Vis-DRS, and PL techniques which proved successful deposition of Fe3O4@WO3 core/shell particle on UiO-66(Zr/Ti)-NFs.	ferryl iron	148-153	delta/notch like EGF repeat containing	Homo sapiens	61-64
33404437-7	2021	The Pb(II) adsorption capacity of cys-delta-FeOOH and Fe3O4 was 97 and 74 mg g-1, respectively.	ferryl iron	54-59	submaxillary gland androgen regulated protein 3B	Homo sapiens	4-10
33379018-2	2021	The hydrophilic composite material functionalized with tris(2-hydroxymethyl)aminomethane (Tris) and Fe3O4 NPs was characterized in detail by ATR-FT-IR, 1H NMR, XRD, EDX peaks and SEM images.	ferryl iron	100-105	ATR serine/threonine kinase	Homo sapiens	141-144
33654131-4	2021	We investigated the effect of spin resonance-mediated heat dissipation using superparamagnetic Fe3O4 nanoparticles and achieved an extraordinary initial temperature increment rate of more than 150 K/s, which is a significant increase in comparison to that for the conventional magnetic heat induction of nanoparticles.	ferryl iron	95-100	spindlin 1	Homo sapiens	30-34
33261864-4	2021	By adding Fe3O4 at concentration of 150 mg/gTS to two typical AFRs, the methane yield was decreased while the methane production rate was significantly enhanced by 48% and 21%, respectively.	ferryl iron	10-15	GTS	Homo sapiens	43-46
33624188-5	2021	The T2W signal-to-noise ratio (SNR) of EGFR-positive SPC-A1 tumors was significantly decreased after scFv@Fe3O4/Au injection, which was not observed in the tumors of mice injected with BSA@Fe3O4/Au.	ferryl iron	189-194	epidermal growth factor receptor	Mus musculus	39-43
33624188-2	2021	Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe3O4/Au nanoparticles to form an EGFR-specific molecular MRI bioprobe (scFv@Fe3O4/Au) to better detect EGFR-positive NSCLC tumors in vivo.	ferryl iron	71-76	epidermal growth factor receptor	Mus musculus	105-109
33624188-2	2021	Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe3O4/Au nanoparticles to form an EGFR-specific molecular MRI bioprobe (scFv@Fe3O4/Au) to better detect EGFR-positive NSCLC tumors in vivo.	ferryl iron	71-76	epidermal growth factor receptor	Mus musculus	105-109
33624188-2	2021	Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe3O4/Au nanoparticles to form an EGFR-specific molecular MRI bioprobe (scFv@Fe3O4/Au) to better detect EGFR-positive NSCLC tumors in vivo.	ferryl iron	148-153	epidermal growth factor receptor	Mus musculus	105-109
33624188-2	2021	Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe3O4/Au nanoparticles to form an EGFR-specific molecular MRI bioprobe (scFv@Fe3O4/Au) to better detect EGFR-positive NSCLC tumors in vivo.	ferryl iron	148-153	epidermal growth factor receptor	Mus musculus	105-109
33624188-3	2021	In vitro, we demonstrated that the EGFR-specific scFv could specifically deliver Fe3O4/Au to EGFR-positive NSCLC cells.	ferryl iron	81-86	epidermal growth factor receptor	Mus musculus	35-39
33624188-3	2021	In vitro, we demonstrated that the EGFR-specific scFv could specifically deliver Fe3O4/Au to EGFR-positive NSCLC cells.	ferryl iron	81-86	epidermal growth factor receptor	Mus musculus	93-97
33624188-5	2021	The T2W signal-to-noise ratio (SNR) of EGFR-positive SPC-A1 tumors was significantly decreased after scFv@Fe3O4/Au injection, which was not observed in the tumors of mice injected with BSA@Fe3O4/Au.	ferryl iron	106-111	epidermal growth factor receptor	Mus musculus	39-43
33461719-6	2021	As expected, Fe3O4@mPDA@Ti4+ revealed a great selectivity (1:200) and a low detection limit (0.1 fmol muL-1) toward phosphopeptides.	ferryl iron	13-18	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	102-107
33673298-11	2021	Future work will address three main aspects: firstly, the implementation of the Fe3O4-PIMs for the removal of As(V) in real water containing complex matrices; secondly, the study of phosphate recovery with other cell designs that allow large volumes of contaminated water to be treated; and thirdly, the investigation of the role of MWCNTs in PIM stability.	ferryl iron	80-85	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	86-89
33246781-0	2021	Fe3O4 magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7.	ferryl iron	0-5	RAB7, member RAS oncogene family	Mus musculus	108-112
33037594-2	2021	Results showed that an appropriate dose of Fe3O4@SiO2 NPs (0.3 g/L) could promote the removal efficiency of TN and TP.	ferryl iron	43-48	C-type lectin domain family 3 member B	Homo sapiens	108-110
33265041-2	2021	Herein, a novel adsorbent, core-shell phase-transited lysozyme film-coated magnetic nanoparticles (Fe3O4@SiO2@PTL) for Hg(II) ions removal from aqueous solutions was explored via facile and fast phase transformation and self-assembly process of lysozyme.	ferryl iron	99-104	lysozyme	Homo sapiens	54-62
33265041-2	2021	Herein, a novel adsorbent, core-shell phase-transited lysozyme film-coated magnetic nanoparticles (Fe3O4@SiO2@PTL) for Hg(II) ions removal from aqueous solutions was explored via facile and fast phase transformation and self-assembly process of lysozyme.	ferryl iron	99-104	lysozyme	Homo sapiens	245-253
33246781-7	2021	However, the application of Fe3O4 magnetic albumin nanoparticles (Fe3O4@BSA) enhanced MMP-2 activity and alleviated renal tubular injury, and these changes were mediated by an autophagy-dependent mechanism.	ferryl iron	28-33	matrix metallopeptidase 2	Mus musculus	86-91
33246781-7	2021	However, the application of Fe3O4 magnetic albumin nanoparticles (Fe3O4@BSA) enhanced MMP-2 activity and alleviated renal tubular injury, and these changes were mediated by an autophagy-dependent mechanism.	ferryl iron	66-71	matrix metallopeptidase 2	Mus musculus	86-91
33372772-2	2021	Herein, an elegant and robust PEC biosensor for carcinoembryonic antigen (CEA) has been designed by photocurrent polarity switching of CdTe quantum dots (QDs), which is obtained by embedding methylene blue (MB) into amplified double-stranded DNA (dsDNA) anchored to the superparamagnetic Fe3O4@SiO2.	ferryl iron	288-293	CEA cell adhesion molecule 3	Homo sapiens	48-72
31927717-2	2021	The Fe3O4@C@OSO3H was manufactured through a simple and inexpensive two-step procedure and characterized by FTIR, EDX, XRD, SEM, TEM, DLS, VSM, and TGA techniques.	ferryl iron	4-9	T-box transcription factor 1	Homo sapiens	148-151
33303136-4	2021	Additionally, the CHA-Fe3O4@C was successfully applied in imaging visualization of miRNA-20a in the living cell.	ferryl iron	22-27	transcription factor like 5	Homo sapiens	18-21
33303136-4	2021	Additionally, the CHA-Fe3O4@C was successfully applied in imaging visualization of miRNA-20a in the living cell.	ferryl iron	22-27	microRNA 20a	Homo sapiens	83-92
33507410-3	2021	In the assay, AFB1-TRCA binds to rGO-Fe3O4-mAb in the absence of AFM1, quenching the fluorescence of TRCA by resonance energy transfer.	ferryl iron	37-42	T cell receptor alpha constant	Homo sapiens	19-23
33507410-3	2021	In the assay, AFB1-TRCA binds to rGO-Fe3O4-mAb in the absence of AFM1, quenching the fluorescence of TRCA by resonance energy transfer.	ferryl iron	37-42	T cell receptor alpha constant	Homo sapiens	101-105
33504835-1	2021	A magnetic Fe3O4@MgAl-layered double hydroxide (MLDH) nanocomposite was successfully synthesized and applied as an effective adsorbent for preconcentration of trace As(III), Cd(II), Cr(III), Co(II), Ni(II), and Pb(II) ions from complex matrices.	ferryl iron	11-16	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	191-197
33372772-2	2021	Herein, an elegant and robust PEC biosensor for carcinoembryonic antigen (CEA) has been designed by photocurrent polarity switching of CdTe quantum dots (QDs), which is obtained by embedding methylene blue (MB) into amplified double-stranded DNA (dsDNA) anchored to the superparamagnetic Fe3O4@SiO2.	ferryl iron	288-293	CEA cell adhesion molecule 3	Homo sapiens	74-77
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	36-41	transferrin	Homo sapiens	163-174
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	36-41	transferrin	Homo sapiens	176-179
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	36-41	transferrin	Homo sapiens	286-289
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	123-128	transferrin	Homo sapiens	163-174
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	123-128	transferrin	Homo sapiens	176-179
33289778-7	2021	The electrostatic repulsion between Fe3O4@SiO2@poly (2-aminoethyl methacrylate hydrochloride)-4-carboxyphenylboronic acid (Fe3O4@SiO2@PAMA-CPBA) nanoparticles and transferrin (TRF) was far greater than the specific binding between phenylboric acid of CPBA and glycosylation residues of TRF resulting in the release of the captured glycoproteins in alkaline solution.	ferryl iron	123-128	transferrin	Homo sapiens	286-289
33326925-3	2021	C18-VK-VI can readily self-assemble into complete monolayers mainly composed of beta-sheets with C18 hydrophobic chains erecting on the surface of GO@Fe3O4 MNCs under the physiological conditions.	ferryl iron	150-155	Bardet-Biedl syndrome 9	Homo sapiens	0-3
33403850-4	2021	Herein, based on the Fe3O4 nanoparticle, we developed a fibroblast growth factor (bFGF)-loaded Fe3O4 nanoparticle using a simple mussel-inspired surface immobilization method.	ferryl iron	21-26	fibroblast growth factor 2	Homo sapiens	82-86
33403850-4	2021	Herein, based on the Fe3O4 nanoparticle, we developed a fibroblast growth factor (bFGF)-loaded Fe3O4 nanoparticle using a simple mussel-inspired surface immobilization method.	ferryl iron	95-100	fibroblast growth factor 2	Homo sapiens	82-86
33403850-5	2021	This nanoparticle, named as bFGF-HDC@Fe3O4, could stabilize bFGF in various conditions and exhibited sustained release of bFGF.	ferryl iron	37-42	fibroblast growth factor 2	Homo sapiens	28-32
33403850-5	2021	This nanoparticle, named as bFGF-HDC@Fe3O4, could stabilize bFGF in various conditions and exhibited sustained release of bFGF.	ferryl iron	37-42	histidine decarboxylase	Homo sapiens	33-36
33403850-5	2021	This nanoparticle, named as bFGF-HDC@Fe3O4, could stabilize bFGF in various conditions and exhibited sustained release of bFGF.	ferryl iron	37-42	fibroblast growth factor 2	Homo sapiens	60-64
33403850-5	2021	This nanoparticle, named as bFGF-HDC@Fe3O4, could stabilize bFGF in various conditions and exhibited sustained release of bFGF.	ferryl iron	37-42	fibroblast growth factor 2	Homo sapiens	60-64
33403850-6	2021	In addition, an in vitro study discovered that bFGF-HDC@Fe3O4 could promote macrophage polarization toward an anti-inflammatory (pro-healing) M2 phenotype especially under eMF.	ferryl iron	56-61	fibroblast growth factor 2	Homo sapiens	47-51
33403850-6	2021	In addition, an in vitro study discovered that bFGF-HDC@Fe3O4 could promote macrophage polarization toward an anti-inflammatory (pro-healing) M2 phenotype especially under eMF.	ferryl iron	56-61	histidine decarboxylase	Homo sapiens	52-55
33403850-7	2021	Further, in vivo full-thickness wound animal models demonstrated that bFGF-HDC@Fe3O4 could significantly accelerate wound healing through M2 macrophage polarization and increased cell proliferation.	ferryl iron	79-84	fibroblast growth factor 2	Homo sapiens	70-74
33403850-7	2021	Further, in vivo full-thickness wound animal models demonstrated that bFGF-HDC@Fe3O4 could significantly accelerate wound healing through M2 macrophage polarization and increased cell proliferation.	ferryl iron	79-84	histidine decarboxylase	Homo sapiens	75-78
33157405-3	2021	Herein, a SiO2, gelatin and biotinylated EpCAM aptamer P1 modified Fe3O4 immunomagnetic nanoparticles (IMNs) were prepared for the specific capture and nondestructive release of trace amounts of CTCs.	ferryl iron	67-72	epithelial cell adhesion molecule	Homo sapiens	41-46
33346645-4	2021	We find that Fe3O4 nanozymes exhibit triple enzyme-like activities, peroxidase, catalase, and superoxide dismutase, thus potentially possessing the ability to regulate the ROS level.	ferryl iron	13-18	catalase	Homo sapiens	80-88
33346645-6	2021	Ex vivo analysis shows that PEG-modified Fe3O4 nanozymes localize in the cerebral vasculature, ameliorate local redox state with decreased malondialdehyde and increased Cu/Zn SOD, and facilitate blood-brain-barrier recovery by elevating ZO-1 and Claudin-5 in the hippocampus.	ferryl iron	41-46	tight junction protein 1	Homo sapiens	237-241
33346645-6	2021	Ex vivo analysis shows that PEG-modified Fe3O4 nanozymes localize in the cerebral vasculature, ameliorate local redox state with decreased malondialdehyde and increased Cu/Zn SOD, and facilitate blood-brain-barrier recovery by elevating ZO-1 and Claudin-5 in the hippocampus.	ferryl iron	41-46	claudin 5	Homo sapiens	246-255
33326925-4	2021	The resulting C18VK-VI-GO@Fe3O4 MNCs exhibited good performance for peptides enrichment from digests of standard protein (myoglobin, MYO) and human serum, such as high sensitivity (0.05 fmol muL-1) and selectivity (mass ratio of MYO digests and MYO = 1:500), rapid separation, and good reproducibility.	ferryl iron	26-31	myoglobin	Homo sapiens	122-131
33326925-4	2021	The resulting C18VK-VI-GO@Fe3O4 MNCs exhibited good performance for peptides enrichment from digests of standard protein (myoglobin, MYO) and human serum, such as high sensitivity (0.05 fmol muL-1) and selectivity (mass ratio of MYO digests and MYO = 1:500), rapid separation, and good reproducibility.	ferryl iron	26-31	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	191-196
33340749-2	2021	Fe3O4@Co-TA was characterized by transmission electron microscopy, scanning electron microscopy, hysteresis loop (B-H) analysis, Fourier-transform infrared spectroscopy, and N2 adsorption-desorption.	ferryl iron	0-5	bleomycin hydrolase	Homo sapiens	114-117
33048173-0	2021	Au-coated Fe3O4 core-shell nanohybrids with photothermal activity for point-of-care immunoassay for lipoprotein-associated phospholipase A2 on a digital near-infrared thermometer.	ferryl iron	10-15	phospholipase A2 group VII	Homo sapiens	100-139
33490824-9	2021	PL, EIS, and TPR showed that Fe3O4/Bi2WO6 has an efficient separation and transfer rate of the photo-generated carriers.	ferryl iron	29-34	translocated promoter region, nuclear basket protein	Homo sapiens	13-16
32659590-3	2021	The CNF supporter could greatly reduce the magnetization of Fe3O4 and increase the coercivity, which effectively avoided agglomeration.	ferryl iron	60-65	NPHS1 adhesion molecule, nephrin	Homo sapiens	4-7
33048173-1	2021	A portable photothermal immunoassay based on Au-coated magnetic Fe3O4 core-shell nanohybrids (Au-Fe3O4) was developed for point-of-care (POC) testing of lipoprotein-associated phospholipase A2 (Lp-PLA2) on a digital near-infrared (NIR) thermometer.	ferryl iron	97-102	phospholipase A2 group VII	Homo sapiens	153-192
33048173-1	2021	A portable photothermal immunoassay based on Au-coated magnetic Fe3O4 core-shell nanohybrids (Au-Fe3O4) was developed for point-of-care (POC) testing of lipoprotein-associated phospholipase A2 (Lp-PLA2) on a digital near-infrared (NIR) thermometer.	ferryl iron	97-102	phospholipase A2 group VII	Homo sapiens	194-201
33142584-6	2021	NCJC/Fe3O4/Ag nanocomposite particles (0.005 mg mL-1) completely degraded 20 mL of 0.1 mM congo red aqueous solution within 13 min aided by NaBH4 reducing agent.	ferryl iron	5-10	L1 cell adhesion molecule	Mus musculus	48-52
32841880-5	2021	Factors influencing the catalytic activity of the Fe3O4-NCS-2 were systematically investigated.	ferryl iron	50-55	cytosolic thiouridylase subunit 2	Homo sapiens	56-61
32841880-9	2021	It is estimated that 1O2 and hydroxyl radicals ( OH) contributed ~65.2% and ~24.2% to TC degradation in the Fe3O4-NCS-2/PMS system, respectively.	ferryl iron	108-113	cytosolic thiouridylase subunit 2	Homo sapiens	114-119
32841880-10	2021	The M-H hysteresis loop of Fe3O4-NCS-2 revealed that its saturation moment is 56 emu g-1.	ferryl iron	27-32	cytosolic thiouridylase subunit 2	Homo sapiens	33-38
32841880-12	2021	This novel magnetic Fe3O4-NCS-2 composite activator for PMS promises great potential in TC degradation.	ferryl iron	20-25	cytosolic thiouridylase subunit 2	Homo sapiens	26-31
32771728-0	2021	Amine-promoted Ru1/Fe3O4 encapsulated in hollow periodic mesoporousorganosilica sphere as a highly selective and stable catalyst for aqueous levulinic acid hydrogenation.	ferryl iron	19-24	Scm like with four mbt domains 1	Homo sapiens	15-18
32771728-5	2021	As expected, the amine-promoted Ru1/Fe3O4 core in the hollow PMO shell (denoted as N-Ru1/Fe3O4@void@PMO), proves to be highly selective and stable for the aqueous levulinic acid (LA) hydrogenation under harsh conditions (pH   1), giving gamma-valerolactone (GVL), a biomass-derived platform molecule with wide applications in the preparation of renewable chemicals and liquid transportation fuels.	ferryl iron	36-41	Scm like with four mbt domains 1	Homo sapiens	32-35
32771728-5	2021	As expected, the amine-promoted Ru1/Fe3O4 core in the hollow PMO shell (denoted as N-Ru1/Fe3O4@void@PMO), proves to be highly selective and stable for the aqueous levulinic acid (LA) hydrogenation under harsh conditions (pH   1), giving gamma-valerolactone (GVL), a biomass-derived platform molecule with wide applications in the preparation of renewable chemicals and liquid transportation fuels.	ferryl iron	89-94	Scm like with four mbt domains 1	Homo sapiens	32-35
33504706-1	2021	Fe3O4 nanoparticles-based magnetic Mo(VI) surface ion-imprinted polymer (Mo(VI)-MIIP) was elaborated employing 4-vinyl pyridine as a functional monomer.	ferryl iron	0-5	migration and invasion inhibitory protein	Homo sapiens	80-84
33254996-0	2021	Facile synthesis of nanogels modified Fe3O4@Ag NPs for the efficient adsorption of bovine & human serum albumin.	ferryl iron	38-43	albumin	Homo sapiens	98-111
33254996-5	2021	The Fe3O4@Ag@SiO2-PNIPA polymeric composites were assessed for the adsorption of Bovine Serum Albumin (BSA) and Human Serum Albumin (HSA) proteins from aqueous media.	ferryl iron	4-9	albumin	Homo sapiens	88-101
33076118-4	2021	Here, a new biocompatible material (denoted as Fe3O4@TiO2-CD63 aptamer) is designed and synthesized for rapid exosome isolation from human urine, depending on the double interactions of TiO2 with phosphate groups as well as aptamers with specific exosome proteins.	ferryl iron	47-52	CD63 molecule	Homo sapiens	58-62
33076118-5	2021	Moreover, within 10 min, 92.6% exosomes with intact structure are captured from urine by Fe3O4@TiO2-CD63 aptamers, from which 999 proteins are detected through LC-MS/MS.	ferryl iron	89-94	CD63 molecule	Homo sapiens	100-104
33504707-4	2021	These results suggested that the AAMA was the aggregates of Fe3O4 nanoparticles with a diameter of about 50-100 nm and had selectivity for Cd2+ adsorption.	ferryl iron	60-65	CD2 molecule	Homo sapiens	139-142
33458549-2	2021	In this study, the novel disulfide cross-linked poly(methacrylic acid) iron oxide (Fe3O4@S-S/PMAA) nanoparticles with selective adsorption, improved adsorption capability, and economic reusability were designed and prepared for selective adsorption of Pb(II) ions in aqueous solution.	ferryl iron	83-88	submaxillary gland androgen regulated protein 3B	Homo sapiens	252-258
33458549-4	2021	The effect of different factors on adsorption properties of the Fe3O4@S-S/PMAA nanoparticles for Co(II) and Pb(II) ions in aqueous solution was explored by batch adsorption experiments.	ferryl iron	64-69	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	97-103
33458549-4	2021	The effect of different factors on adsorption properties of the Fe3O4@S-S/PMAA nanoparticles for Co(II) and Pb(II) ions in aqueous solution was explored by batch adsorption experiments.	ferryl iron	64-69	submaxillary gland androgen regulated protein 3B	Homo sapiens	108-114
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	58-63	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-83
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	58-63	submaxillary gland androgen regulated protein 3B	Homo sapiens	88-94
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	58-63	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	202-208
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	58-63	submaxillary gland androgen regulated protein 3B	Homo sapiens	213-219
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	183-188	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-83
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	183-188	submaxillary gland androgen regulated protein 3B	Homo sapiens	88-94
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	183-188	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	202-208
33458549-5	2021	For adsorption mechanism investigation, the adsorption of Fe3O4@S-S/PMAA for Co(II) and Pb(II) ions can be better fitted by a pseudo-second-order model, and the adsorption process of Fe3O4@S-S/PMAA for Co(II) and Pb(II) matches well with the Freundlich isotherm equation.	ferryl iron	183-188	submaxillary gland androgen regulated protein 3B	Homo sapiens	213-219
33458549-6	2021	Notably, in the adsorption experiments, the Fe3O4@S-S/PMAA nanoparticles were demonstrated to have a maximum adsorption capacity of 48.7 mg g-1 on Pb(II) ions with a selective adsorption order of Pb2+ > Co2+ > Cd2+ > Ni2+ > Cu2+ > Zn2+ > K+ > Na+ > Mg2+ > Ca2+ in the selective experiments.	ferryl iron	44-49	submaxillary gland androgen regulated protein 3B	Homo sapiens	147-153
33458549-7	2021	In the regeneration experiments, the Fe3O4@S-S/PMAA nanoparticles could be easily recovered by desorbing heavy metal ions from the adsorbents with eluents and showed good adsorption capacity for Co(II) and Pb(II) after eight recycles.	ferryl iron	37-42	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	195-201
33458549-7	2021	In the regeneration experiments, the Fe3O4@S-S/PMAA nanoparticles could be easily recovered by desorbing heavy metal ions from the adsorbents with eluents and showed good adsorption capacity for Co(II) and Pb(II) after eight recycles.	ferryl iron	37-42	submaxillary gland androgen regulated protein 3B	Homo sapiens	206-212
33458549-8	2021	In brief, compared to other traditional nanoadsorbents, the as-prepared Fe3O4@S-S/PMAA with improved adsorption capability and high regeneration efficiency demonstrated remarkable affinity for adsorption of Pb(II) ions, which will provide a novel technical platform for selective removal of heavy metal ions from actual polluted water.	ferryl iron	72-77	submaxillary gland androgen regulated protein 3B	Homo sapiens	207-213
33010266-1	2020	A novel ethylenediaminetetraacetic acid (EDTA)-functionalized magnetic chitosan oligosaccharide and carboxymethyl cellulose (Fe3O4@CMCCOS-EDTA) nanocomposite adsorbent was successfully fabricated for Pb(II) adsorption.	ferryl iron	125-130	submaxillary gland androgen regulated protein 3B	Homo sapiens	200-206
33218485-4	2020	Acetylcholinesterase was immobilized to fabricate the enzyme reactor Fe3O4@COF-Apt-AChE through the high affinity and specificity with its binding aptamer.	ferryl iron	69-74	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-20
33218485-4	2020	Acetylcholinesterase was immobilized to fabricate the enzyme reactor Fe3O4@COF-Apt-AChE through the high affinity and specificity with its binding aptamer.	ferryl iron	69-74	acetylcholinesterase (Cartwright blood group)	Homo sapiens	83-87
33155581-5	2020	Meanwhile, Fe3O4@mSiO2-PA administration in vivo markedly suppresses HeLa tumor xenografts growth via the induction of apoptosis, followed by caspase-3 activation and cytochrome C release.	ferryl iron	11-16	caspase 3	Homo sapiens	142-151
33155581-6	2020	Further investigation revealed that Fe3O4@mSiO2-PA causes enhanced production of reactive oxygen species (ROS), which subsequently triggers DNA damage and causes dysfunction of the MAPK and PI3K/AKT pathways.	ferryl iron	36-41	AKT serine/threonine kinase 1	Homo sapiens	195-198
33010266-6	2020	The maximum adsorption capacity (qm) for monolayer chemical adsorption was calculated to be 432.34 mg/g at the pH of 5 and temperature of 308 K. Notably, Fe3O4@CMCCOS-EDTA exhibited a high Pb(II) removal rate of ~100% using an initial metal ion solution of 100 mg/L and 200 mg/L.	ferryl iron	154-159	submaxillary gland androgen regulated protein 3B	Homo sapiens	189-195
33321215-7	2021	Further testing showed that Fe3O4@M effectively targets early atherosclerotic lesions by the specific recognition of integrin alpha4beta1 to VCAM-1.	ferryl iron	28-33	vascular cell adhesion molecule 1	Homo sapiens	141-147
32889499-10	2020	The Fe3O4@SiO2@Se adsorbent effectively removed the Hg (II) ions spiked to different samples, including tap water, river water, seawater, and industrial wastewater.	ferryl iron	4-9	nuclear RNA export factor 1	Homo sapiens	104-107
33505202-6	2020	Experimental approach: Pectinase was immobilized in four steps: relative oxidation of kefiran and its application as a cross-linker, production of magnetic iron(II) iron(III) oxide (Fe3O4) microparticles, coating of magnetic Fe3O4 microparticles with chitosan, and immobilization of the enzyme on the substrate, prepared by the use of oxidized kefiran cross-linker.	ferryl iron	182-187	polygalacturonase	Malus domestica	23-32
32272856-5	2020	Our results outlined that ZnO/CNT@Fe3O4 decreased the proliferative capacity of K562 cells through induction of G1 arrest and induced apoptosis probably via ROS-dependent upregulation of FOXO3a and SIRT1.	ferryl iron	34-39	forkhead box O3	Homo sapiens	187-193
32272856-5	2020	Our results outlined that ZnO/CNT@Fe3O4 decreased the proliferative capacity of K562 cells through induction of G1 arrest and induced apoptosis probably via ROS-dependent upregulation of FOXO3a and SIRT1.	ferryl iron	34-39	sirtuin 1	Homo sapiens	198-203
32927448-6	2020	Our SERS platform comprises a magnetite core with an intermediate silica shell, and a flower-shaped silver layer (Fe3O4@SiO2@Ag) to confer excellent plasmonic properties and ease of collection by magnetism.	ferryl iron	114-119	seryl-tRNA synthetase 1	Homo sapiens	4-8
33505202-6	2020	Experimental approach: Pectinase was immobilized in four steps: relative oxidation of kefiran and its application as a cross-linker, production of magnetic iron(II) iron(III) oxide (Fe3O4) microparticles, coating of magnetic Fe3O4 microparticles with chitosan, and immobilization of the enzyme on the substrate, prepared by the use of oxidized kefiran cross-linker.	ferryl iron	225-230	polygalacturonase	Malus domestica	23-32
33505202-10	2020	Results and conclusions: Cross-linker concentration, cross-linking time and the ratio of magnetic Fe3O4 microparticles with chitosan to enzyme were important factors in activity recovery of pectinase.	ferryl iron	98-103	polygalacturonase	Malus domestica	190-199
33126072-0	2020	Online coupling Fe3O4@ZIF-67@alpha-glucosidase biomicroreactor with high performance liquid chromatography for rapid screening of alpha-glucosidase inhibitors in tea and their inhibitory activity research.	ferryl iron	16-21	sucrase-isomaltase	Homo sapiens	29-46
33101492-0	2020	Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype.	ferryl iron	31-36	mannose receptor, C type 1	Mus musculus	5-10
33126072-0	2020	Online coupling Fe3O4@ZIF-67@alpha-glucosidase biomicroreactor with high performance liquid chromatography for rapid screening of alpha-glucosidase inhibitors in tea and their inhibitory activity research.	ferryl iron	16-21	sucrase-isomaltase	Homo sapiens	130-147
33126072-1	2020	In this work, alpha-glucosidase was immobilized on a type of nanoscaledmagnetic materials Fe3O4@ZIF-67 to construct a biomicroreactor for rapid screening alpha-glucosidase inhibitors.	ferryl iron	90-95	sucrase-isomaltase	Homo sapiens	14-31
33126072-1	2020	In this work, alpha-glucosidase was immobilized on a type of nanoscaledmagnetic materials Fe3O4@ZIF-67 to construct a biomicroreactor for rapid screening alpha-glucosidase inhibitors.	ferryl iron	90-95	sucrase-isomaltase	Homo sapiens	154-171
33220508-4	2021	Next, to develop a tumor-targeted contrast agent, the DHCA-Fe@Fe3O4 nanoparticles were conjugated with the F56 peptide, which targets the vascular endothelial growth factor receptor, and the resulting F56-DHCA-Fe@Fe3O4 nanoparticles were found to exhibit good T1-T2 dual-mode imaging and tumor-targeting performance both in vitro and in vivo, indicating the nanoparticles represent a new research tool for accurate tumor diagnosis.	ferryl iron	62-67	DLEC1 cilia and flagella associated protein	Homo sapiens	107-110
33220508-4	2021	Next, to develop a tumor-targeted contrast agent, the DHCA-Fe@Fe3O4 nanoparticles were conjugated with the F56 peptide, which targets the vascular endothelial growth factor receptor, and the resulting F56-DHCA-Fe@Fe3O4 nanoparticles were found to exhibit good T1-T2 dual-mode imaging and tumor-targeting performance both in vitro and in vivo, indicating the nanoparticles represent a new research tool for accurate tumor diagnosis.	ferryl iron	62-67	DLEC1 cilia and flagella associated protein	Homo sapiens	201-204
33220508-4	2021	Next, to develop a tumor-targeted contrast agent, the DHCA-Fe@Fe3O4 nanoparticles were conjugated with the F56 peptide, which targets the vascular endothelial growth factor receptor, and the resulting F56-DHCA-Fe@Fe3O4 nanoparticles were found to exhibit good T1-T2 dual-mode imaging and tumor-targeting performance both in vitro and in vivo, indicating the nanoparticles represent a new research tool for accurate tumor diagnosis.	ferryl iron	213-218	DLEC1 cilia and flagella associated protein	Homo sapiens	201-204
32985626-6	2020	Moreover, when the magnetic field and bone morphogenetic protein-2 (BMP2) delivered by Fe3O4@GO MNCs worked together, osteogenic differentiation of MSCs in vitro was well promoted.	ferryl iron	87-92	bone morphogenetic protein 2	Rattus norvegicus	38-66
33197900-5	2021	Investigating the molecular mechanisms involved in the growth-suppressive effect of ZnO/CNT@Fe3O4-plus-Imatinib clarified that the up-regulation of SIRT1 ceased the progression of the cell cycle, foremost by increasing the expression of p21 and p27 cyclin-dependent kinase inhibitors.	ferryl iron	92-97	sirtuin 1	Homo sapiens	148-153
33197900-5	2021	Investigating the molecular mechanisms involved in the growth-suppressive effect of ZnO/CNT@Fe3O4-plus-Imatinib clarified that the up-regulation of SIRT1 ceased the progression of the cell cycle, foremost by increasing the expression of p21 and p27 cyclin-dependent kinase inhibitors.	ferryl iron	92-97	cyclin dependent kinase inhibitor 1A	Homo sapiens	237-240
33197900-5	2021	Investigating the molecular mechanisms involved in the growth-suppressive effect of ZnO/CNT@Fe3O4-plus-Imatinib clarified that the up-regulation of SIRT1 ceased the progression of the cell cycle, foremost by increasing the expression of p21 and p27 cyclin-dependent kinase inhibitors.	ferryl iron	92-97	dynactin subunit 6	Homo sapiens	245-248
33197900-6	2021	Notably, we reported for the first time that either direct or indirect suppression of c-Myc resulted in an enhanced anti-leukemic effect; suggesting that the overexpression of c-Myc could play a contributory role in attenuating the efficacy of ZnO/CNT@Fe3O4-plus-Imatinib in K562.	ferryl iron	252-257	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	86-91
33197900-6	2021	Notably, we reported for the first time that either direct or indirect suppression of c-Myc resulted in an enhanced anti-leukemic effect; suggesting that the overexpression of c-Myc could play a contributory role in attenuating the efficacy of ZnO/CNT@Fe3O4-plus-Imatinib in K562.	ferryl iron	252-257	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	176-181
33086013-3	2020	This study reports the construction of a multifunctional nanoagent (FIP-99mTc) that comprises Fe3O4 for magnetic resonance imaging, radioactive 99mTc for single-photon-emission computed tomography, and IR-1061 to serve for the second near-infrared fluorescence imaging, photoacoustic imaging, and photothermal therapy treatment of cancer metastasis.	ferryl iron	94-99	upstream transcription factor 2, c-fos interacting	Homo sapiens	68-71
32711205-1	2020	Magnetic Fe3O4 nanoparticles were coated by polyethyleneimine (PEI), and then Fe3O4@PEI was further modified with MoS2 by the hydrothermal method to fabricate 3D flower-like structured magnetic polyethyleneimine@MoS2 (MP@MoS2) composites, and the composites were served as efficient adsorbents to capture Cr(VI) and Pb(II) from aqueous solution.	ferryl iron	78-83	submaxillary gland androgen regulated protein 3B	Homo sapiens	316-322
32985626-6	2020	Moreover, when the magnetic field and bone morphogenetic protein-2 (BMP2) delivered by Fe3O4@GO MNCs worked together, osteogenic differentiation of MSCs in vitro was well promoted.	ferryl iron	87-92	bone morphogenetic protein 2	Rattus norvegicus	68-72
33081946-2	2020	Glycocyamine functionalized magnetic layered double hydroxides (Fe3O4@LDH@NH2-GAA) was fabricated through an easy process.	ferryl iron	64-69	alpha glucosidase	Homo sapiens	78-81
33081946-4	2020	Fe3O4@LDH@NH2-GAA, combining not only metal ions (Cu2+ and Ga3+) in LDH but also functional guanidyl groups in glycocyamine, offered multiple affinity sites for phosphopeptides enrichment.	ferryl iron	0-5	alpha glucosidase	Homo sapiens	14-17
33081946-6	2020	Moreover, the efficient enrichment of phosphopeptides by Fe3O4@LDH@NH2-GAA from nonfat milk, human saliva, serum, and A549 cell lysates further confirmed its great potential for trace biological detection and proteomic analysis.	ferryl iron	57-62	alpha glucosidase	Homo sapiens	71-74
32901482-9	2020	This indeed seen in the kcat obtained for Fe3O4@SHS (GOx added externally during assay), which is 18 times lower than that of GOx-Fe3O4@SHS.	ferryl iron	130-135	hydroxyacid oxidase 1	Homo sapiens	126-129
32901482-4	2020	By tuning both shape and phase (vaterite/calcite and pure calcite) of CaCO3, it allows generation of GOx and Fe3O4-PEI encapsulated silica hollow microspheres (GOx-Fe3O4@SHS) and microcubes (GOx-Fe3O4@SHC).	ferryl iron	109-114	hydroxyacid oxidase 1	Homo sapiens	160-163
32901482-4	2020	By tuning both shape and phase (vaterite/calcite and pure calcite) of CaCO3, it allows generation of GOx and Fe3O4-PEI encapsulated silica hollow microspheres (GOx-Fe3O4@SHS) and microcubes (GOx-Fe3O4@SHC).	ferryl iron	109-114	hydroxyacid oxidase 1	Homo sapiens	160-163
32970073-2	2020	Structural analysis of 1 ascertained a unique Ru-Ru bonded (Ru2-Ru3: 2.5187(6) A (DFT: 2.560 A)) {Ru2(Ru-Ru)(mu3-O)2} butterfly core, unlike the reported other Fe4 or Mn4 derived "butterfly" core.	ferryl iron	160-163	doublecortin domain containing 2	Homo sapiens	60-63
32970073-2	2020	Structural analysis of 1 ascertained a unique Ru-Ru bonded (Ru2-Ru3: 2.5187(6) A (DFT: 2.560 A)) {Ru2(Ru-Ru)(mu3-O)2} butterfly core, unlike the reported other Fe4 or Mn4 derived "butterfly" core.	ferryl iron	160-163	doublecortin domain containing 2	Homo sapiens	98-101
32497673-5	2020	Through conjugation of the anti-CD4 monoclonal antibody on the surface of Fe3O4@SiO2@PMIDA MNP.	ferryl iron	74-79	CD4 molecule	Homo sapiens	32-35
32901482-4	2020	By tuning both shape and phase (vaterite/calcite and pure calcite) of CaCO3, it allows generation of GOx and Fe3O4-PEI encapsulated silica hollow microspheres (GOx-Fe3O4@SHS) and microcubes (GOx-Fe3O4@SHC).	ferryl iron	164-169	hydroxyacid oxidase 1	Homo sapiens	160-163
33001332-0	2020	Sn2+ Doping: A Strategy for Tuning of Fe3O4 Nanoparticles Magnetization Dipping Temperature/Amplitude, Irreversibility, and Curie Point.	ferryl iron	38-43	solute carrier family 38 member 5	Homo sapiens	0-3
32901482-4	2020	By tuning both shape and phase (vaterite/calcite and pure calcite) of CaCO3, it allows generation of GOx and Fe3O4-PEI encapsulated silica hollow microspheres (GOx-Fe3O4@SHS) and microcubes (GOx-Fe3O4@SHC).	ferryl iron	164-169	hydroxyacid oxidase 1	Homo sapiens	160-163
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	63-68	hydroxyacid oxidase 1	Homo sapiens	109-112
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	63-68	hydroxyacid oxidase 1	Homo sapiens	196-199
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	63-68	hydroxyacid oxidase 1	Homo sapiens	196-199
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	113-118	hydroxyacid oxidase 1	Homo sapiens	109-112
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	113-118	hydroxyacid oxidase 1	Homo sapiens	196-199
32901482-6	2020	Comparison of the peroxidase like activity of the encapsulated Fe3O4-PEI shows that the hollow microspheres (GOx-Fe3O4@SHS) results in activity 14 times higher than that of the hollow microcubes (GOx-Fe3O4@SHC), which in turn is corroborated to the differential loading capacity of GOx in microspheres and microcubes.	ferryl iron	113-118	hydroxyacid oxidase 1	Homo sapiens	196-199
32901482-7	2020	The evaluation of kinetic parameters indicates a 5 fold increase in the catalytic constant (kcat) of Fe3O4-PEI confined in hollow microspheres (GOx-Fe3O4@SHS) compared to the mixture comprising of free GOx and Fe3O4-PEI in solution.	ferryl iron	101-106	hydroxyacid oxidase 1	Homo sapiens	144-147
32901482-7	2020	The evaluation of kinetic parameters indicates a 5 fold increase in the catalytic constant (kcat) of Fe3O4-PEI confined in hollow microspheres (GOx-Fe3O4@SHS) compared to the mixture comprising of free GOx and Fe3O4-PEI in solution.	ferryl iron	101-106	hydroxyacid oxidase 1	Homo sapiens	202-205
32901482-9	2020	This indeed seen in the kcat obtained for Fe3O4@SHS (GOx added externally during assay), which is 18 times lower than that of GOx-Fe3O4@SHS.	ferryl iron	42-47	hydroxyacid oxidase 1	Homo sapiens	53-56
32901482-9	2020	This indeed seen in the kcat obtained for Fe3O4@SHS (GOx added externally during assay), which is 18 times lower than that of GOx-Fe3O4@SHS.	ferryl iron	42-47	hydroxyacid oxidase 1	Homo sapiens	126-129
32901482-9	2020	This indeed seen in the kcat obtained for Fe3O4@SHS (GOx added externally during assay), which is 18 times lower than that of GOx-Fe3O4@SHS.	ferryl iron	130-135	hydroxyacid oxidase 1	Homo sapiens	53-56
33001332-2	2020	Sn2+ doping reduces the anticipated oxidation of Fe3O4 NPs to maghemite (gamma-Fe2O3), making them attractive in several magnetic applications.	ferryl iron	49-54	solute carrier family 38 member 5	Homo sapiens	0-3
32782510-0	2020	Preparation and in vitro study of stromal cell-derived factor 1-targeted Fe3O4/poly(lactic-co-glycolic acid)/perfluorohexane nanoparticles.	ferryl iron	73-78	C-X-C motif chemokine ligand 12	Homo sapiens	34-63
32500498-2	2020	The structure and characteristics of the Fe3O4/GO/clay composite were investigated using FT-IR, SEM, EDX/Map, VSM, BET, and XRD analyses.	ferryl iron	41-46	delta/notch like EGF repeat containing	Homo sapiens	115-118
32500498-3	2020	The BET analysis indicated that the specific surface area and mean pore size of the Fe3O4/GO/clay composite were calculated as 61.64 m2/g and 16.2 nm respectively, which indicate that the composite has a mesoporous structure.	ferryl iron	84-89	delta/notch like EGF repeat containing	Homo sapiens	4-7
32941572-2	2020	In this article, biotinylated CD20 and CD3 antibodies were conjugated onto the surface of streptavidin modified ultra-small Fe3O4 nanoparticles via specific binding between streptavidin and biotin to construct a bi-specific nanoplatform (BSNP).	ferryl iron	124-129	keratin 20	Homo sapiens	30-34
32408161-3	2020	Herein, necklace-like Fe3O4/carbon nanofibril aerogel (Fe3O4/CNF) was constructed by crosslinking alginate with Fe3+, followed by carbonization of the obtained ferric alginate aerogel.	ferryl iron	22-27	NPHS1 adhesion molecule, nephrin	Homo sapiens	61-64
32408161-6	2020	These Fe3O4/CNF aerogels may have potential applications for enhanced lithium storage of electrochemical devices.	ferryl iron	6-11	NPHS1 adhesion molecule, nephrin	Homo sapiens	12-15
32820714-1	2021	This investigation indicated an efficient procedure to purify human carbonic anhydrase II (hCA II) enzyme through sulfanilamide-functionalized (gamma-Fe2O3-CPTES-SA) magnetic nanoparticles (MNPs), where synthesis of Fe3O4 MNPs was carried out using co-precipitation reaction.	ferryl iron	216-221	carbonic anhydrase 2	Homo sapiens	68-89
32820714-1	2021	This investigation indicated an efficient procedure to purify human carbonic anhydrase II (hCA II) enzyme through sulfanilamide-functionalized (gamma-Fe2O3-CPTES-SA) magnetic nanoparticles (MNPs), where synthesis of Fe3O4 MNPs was carried out using co-precipitation reaction.	ferryl iron	216-221	carbonic anhydrase 2	Homo sapiens	91-97
32770422-1	2020	A novel label-free and exonuclease III (Exo III)-assisted signal amplification electrochemical aptasensor was constructed for the determination of carcinoembryonic antigen (CEA) via magnetic field-induced self-assembly of magnetic biocomposites (Fe3O4@Au NPs-S1-S2-S3).	ferryl iron	246-251	CEA cell adhesion molecule 3	Homo sapiens	147-171
32663405-6	2020	Magnetic Fe3O4 nanoparticles with 30 nm diameter were enriched at CNF/polymer interfaces, and most of the nanoparticles were encapsulated in the polymer core.	ferryl iron	9-14	NPHS1 adhesion molecule, nephrin	Homo sapiens	66-69
32825193-1	2020	We investigated the opportunities for obtaining hexaferrites Pb1-xLaxFe12-xZnxO19 (x = 0-1) from citrate-glycerin gel and showed that synthesis occurs via the formation of the Fe3O4 phase; products with a small amount of hematite impurity Fe2O3 can be obtained after firing at 800 to 900  C with 0 <= x <= 0.5.	ferryl iron	176-181	submaxillary gland androgen regulated protein 3A	Homo sapiens	61-64
32770422-1	2020	A novel label-free and exonuclease III (Exo III)-assisted signal amplification electrochemical aptasensor was constructed for the determination of carcinoembryonic antigen (CEA) via magnetic field-induced self-assembly of magnetic biocomposites (Fe3O4@Au NPs-S1-S2-S3).	ferryl iron	246-251	CEA cell adhesion molecule 3	Homo sapiens	173-176
32739773-6	2020	In addition, the magnetic Fe3O4@SiO2 nanocomposites exhibit a satisfactory photothermal effect under NIR (808 nm) irradiation.	ferryl iron	26-31	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	101-104
32696774-5	2020	Here, we found that the level of adsorbed heat shock protein 90 kDa alpha class B member 1 (Hsp90ab1) by the denatured protein in iron-cobalt-nickel alloy NPs (FeCoNi NPs) and iron oxide NPs (Fe3O4 NPs) was correlated with circular dichroism (CD) analysis and 1-anilinonaphthalene-8-sulfonate (ANS) analysis.	ferryl iron	192-197	heat shock protein 90 alpha family class B member 1	Homo sapiens	92-100
32739773-10	2020	Furthermore, 81.3% of A549 lung cancer cells are killed after incubation with Fe3O4@SiO2@DOX that contains only 0.5 mug/mL of DOX and 15 min of NIR irradiation, thereby suggesting an excellent synergistic chemo-photothermal effect in tumour therapy.	ferryl iron	78-83	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	144-147
32558533-2	2020	Herein, for the first time, we present a novel heterostructure catalyst, constructed by ultrafine NiS/Fe3O4 heterostruc-tural nanoparticles decorated on CNTs matrix (NiS/Fe3O4 HNPs@CNT), which is synthesized by a facile hydrothermal reaction and subsequent sulfurization process.	ferryl iron	102-107	solute carrier family 5 member 5	Homo sapiens	98-101
32548633-0	2020	Rapid and Sensitive Detection of Aflatoxin B1, B2, G1 and G2 in Vegetable Oils Using Bare Fe3O4 as Magnetic Sorbents Coupled with High-Performance Liquid Chromatography with Fluorescence Detection.	ferryl iron	90-95	apolipoprotein H	Homo sapiens	33-53
32200245-0	2020	Preparation and surface engineering of CM-beta-CD functionalized Fe3O4@TiO2 nanoparticles for photocatalytic degradation of polychlorinated biphenyls (PCBs) from transformer oil.	ferryl iron	65-70	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	42-49
32674324-3	2020	Fe3O4@Me6TREN NPs as an effective nano-adsorbent of heavy metals exhibited significant differences in maximum adsorption capacity for Cr(III) (61.4 mg/g), Cu(II) (245.0 mg/g), Pb(II) (5.3 mg/g), and Cd(II) (1136.2 mg/g), in favor of classified removal of heavy metals from wastewater.	ferryl iron	0-5	submaxillary gland androgen regulated protein 3B	Homo sapiens	176-182
32558533-2	2020	Herein, for the first time, we present a novel heterostructure catalyst, constructed by ultrafine NiS/Fe3O4 heterostruc-tural nanoparticles decorated on CNTs matrix (NiS/Fe3O4 HNPs@CNT), which is synthesized by a facile hydrothermal reaction and subsequent sulfurization process.	ferryl iron	102-107	solute carrier family 5 member 5	Homo sapiens	166-169
32558533-2	2020	Herein, for the first time, we present a novel heterostructure catalyst, constructed by ultrafine NiS/Fe3O4 heterostruc-tural nanoparticles decorated on CNTs matrix (NiS/Fe3O4 HNPs@CNT), which is synthesized by a facile hydrothermal reaction and subsequent sulfurization process.	ferryl iron	170-175	solute carrier family 5 member 5	Homo sapiens	98-101
32388978-4	2020	Herein, a core-shell Fe3O4@Cu2O nanoparticle was constructed as a magnetic-photoacoustic dual-mode probe for H2S detection in vitro and in vivo based on the in situ response of Cu2O to endogenous H2S in colon tumors.	ferryl iron	21-26	histocompatibility 2, S region (C4, Slp, Bf, C2)	Mus musculus	109-112
32802185-3	2020	The thermoacoustic nanoparticles were composed of the galectin-1 antibody for targeting pancreatic tumors and Fe3O4 nanoparticles as microwave absorbers (anti-Gal1-Fe3O4 nanoparticles).	ferryl iron	164-169	lectin, galactose binding, soluble 1	Mus musculus	159-163
32802185-6	2020	MTAI images of the heterozygosity model were acquired with/without the injection of the anti-Gal1-Fe3O4 nanoparticles and the thermoacoustic contrast from pancreatic tumors was evaluated with Student"s paired t test.	ferryl iron	98-103	lectin, galactose binding, soluble 1	Mus musculus	93-97
32802185-9	2020	The MTAI contrast enhancement in pancreatic tumors with anti-Gal1-Fe3O4 nanoparticles was verified in vitro and in vivo.	ferryl iron	66-71	lectin, galactose binding, soluble 1	Mus musculus	61-65
32802185-13	2020	Conclusion: MTAI offers deep imaging depth and high contrast when used with anti-Gal1-Fe3O4 nanoparticles.	ferryl iron	86-91	lectin, galactose binding, soluble 1	Mus musculus	81-85
32054994-12	2020	Enhanced expression of TNF and the activation of NLRP3 and CASP1 followed by the increased generation of IL-1beta and nuclear translocation of the NF-kappabeta transcription factor occurred in response to hemoglobin-derived peptides, and ferryl hemoglobin in endothelium was upregulated in both pathologies.	ferryl iron	238-244	tumor necrosis factor	Homo sapiens	23-26
32054994-12	2020	Enhanced expression of TNF and the activation of NLRP3 and CASP1 followed by the increased generation of IL-1beta and nuclear translocation of the NF-kappabeta transcription factor occurred in response to hemoglobin-derived peptides, and ferryl hemoglobin in endothelium was upregulated in both pathologies.	ferryl iron	238-244	NLR family pyrin domain containing 3	Homo sapiens	49-54
32054994-12	2020	Enhanced expression of TNF and the activation of NLRP3 and CASP1 followed by the increased generation of IL-1beta and nuclear translocation of the NF-kappabeta transcription factor occurred in response to hemoglobin-derived peptides, and ferryl hemoglobin in endothelium was upregulated in both pathologies.	ferryl iron	238-244	caspase 1	Homo sapiens	59-64
32054994-12	2020	Enhanced expression of TNF and the activation of NLRP3 and CASP1 followed by the increased generation of IL-1beta and nuclear translocation of the NF-kappabeta transcription factor occurred in response to hemoglobin-derived peptides, and ferryl hemoglobin in endothelium was upregulated in both pathologies.	ferryl iron	238-244	interleukin 1 alpha	Homo sapiens	105-113
32393955-5	2020	After conjugation with the antibody of epithelial cell adhesion molecule (EpCAM), the biomimetic immunomagnetic gold nanoparticles (CM-Fe3O4@Au-Ab) showed a high specific recognition ability on mock (EpCAM-positive) CTCs and a reduced interaction with leukocytes.	ferryl iron	135-140	epithelial cell adhesion molecule	Homo sapiens	39-72
32393955-5	2020	After conjugation with the antibody of epithelial cell adhesion molecule (EpCAM), the biomimetic immunomagnetic gold nanoparticles (CM-Fe3O4@Au-Ab) showed a high specific recognition ability on mock (EpCAM-positive) CTCs and a reduced interaction with leukocytes.	ferryl iron	135-140	epithelial cell adhesion molecule	Homo sapiens	74-79
32393955-5	2020	After conjugation with the antibody of epithelial cell adhesion molecule (EpCAM), the biomimetic immunomagnetic gold nanoparticles (CM-Fe3O4@Au-Ab) showed a high specific recognition ability on mock (EpCAM-positive) CTCs and a reduced interaction with leukocytes.	ferryl iron	135-140	epithelial cell adhesion molecule	Homo sapiens	200-205
32561829-3	2020	Engaging multiple hydroxyl groups along the molecular backbone of CNC, we co-ordinated Fe3O4 NPs onto CNC scaffold, which was further modified by conjugation with a protein - transferrin (Tf) for targeted capture of CTCs.	ferryl iron	87-92	transferrin	Homo sapiens	175-186
32561829-3	2020	Engaging multiple hydroxyl groups along the molecular backbone of CNC, we co-ordinated Fe3O4 NPs onto CNC scaffold, which was further modified by conjugation with a protein - transferrin (Tf) for targeted capture of CTCs.	ferryl iron	87-92	transferrin	Homo sapiens	188-190
32409040-2	2020	For this purpose, the surface of lipase was initially coated with Triton-X 100 and cetyltrimethylammonium bromide surfactants, to stabilize enzyme in its open form and was then adsorbed onto aminated Fe3O4/SiO2/Gr NC.	ferryl iron	200-205	lipase	Malus domestica	33-39
32409056-4	2020	The green synthesized Fe3O4@SiO2-Glu nanoparticles exhibited multilayer architecture with a BET surface area of 79.9 m2/g and a magnetization saturation of 25.9 emu/g.	ferryl iron	22-27	delta/notch like EGF repeat containing	Homo sapiens	92-95
32572637-3	2020	The phosphopeptide enrichment efficiency of the Fe3O4@mSiO2@Ti4+-Zr4+ composite was investigated, and the result indicated an ultrahigh size exclusive ability (weight ratio of beta-casein tryptic digests, BSA, and alpha-casein protein reached up to 1:1000:1000).	ferryl iron	48-53	casein beta	Homo sapiens	176-187
32572117-0	2020	Synthesis of diglycolic acid functionalized core-shell silica coated Fe3O4 nanomaterials for magnetic extraction of Pb(II) and Cr(VI) ions.	ferryl iron	69-74	submaxillary gland androgen regulated protein 3B	Homo sapiens	116-122
32388978-4	2020	Herein, a core-shell Fe3O4@Cu2O nanoparticle was constructed as a magnetic-photoacoustic dual-mode probe for H2S detection in vitro and in vivo based on the in situ response of Cu2O to endogenous H2S in colon tumors.	ferryl iron	21-26	histocompatibility 2, S region (C4, Slp, Bf, C2)	Mus musculus	196-199
32393021-3	2020	To overcome these drawbacks, in this work, a unique split-type PEC aptasensor for carcinoembryonic antigen (CEA) was developed in virtue of the sandwich-like structure comprised of magnetic-optical Fe3O4@SiO2@CdS-DNA1, CEA aptamer, and signal element SiO2-Au-DNA2.	ferryl iron	198-203	CEA cell adhesion molecule 3	Homo sapiens	82-106
32393021-3	2020	To overcome these drawbacks, in this work, a unique split-type PEC aptasensor for carcinoembryonic antigen (CEA) was developed in virtue of the sandwich-like structure comprised of magnetic-optical Fe3O4@SiO2@CdS-DNA1, CEA aptamer, and signal element SiO2-Au-DNA2.	ferryl iron	198-203	CEA cell adhesion molecule 3	Homo sapiens	108-111
32379252-7	2020	Fe3O4@SiO2@TpPa-Ti4+ nanoparticles also demonstrate high sensitivity (above 0.2 fmol muL-1) and selectivity (alpha-casein : BSA = 1 : 5000).	ferryl iron	0-5	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	85-90
32533266-2	2020	Firstly, ADANPs and magnetic substrate of Fe3O4 nanoparticles were covalently attached to the 3"- and 5"- end of capture probe (CP) targeting miRNA-21.	ferryl iron	42-47	microRNA 21	Homo sapiens	142-150
32533266-3	2020	Upon the addition of target miRNA-21, these heteroduplexes were specifically cleaved by DSN and resulted in ADANPs that were released from the surface of Fe3O4 nanoparticles (Fe3O4 NPs).	ferryl iron	154-159	microRNA 21	Homo sapiens	28-36
32533266-3	2020	Upon the addition of target miRNA-21, these heteroduplexes were specifically cleaved by DSN and resulted in ADANPs that were released from the surface of Fe3O4 nanoparticles (Fe3O4 NPs).	ferryl iron	175-180	microRNA 21	Homo sapiens	28-36
32533266-7	2020	Graphical abstract a shows the synthesis of Fe3O4 NPs and the conjugation of Au@DTNB@Ag NPs (ADANPs) for the detection of miRNA-21, b shows the operating principle of DSN-assisted signal amplification strategy for miRNA detection based on Fe3O4@CP@ADA NPs.	ferryl iron	239-244	microRNA 21	Homo sapiens	122-130
32175824-6	2020	Furthermore, all the release behaviors fit the Higuchi model very well and the dissolution of CS/PEG layers played a key role on DOX release from Fe3O4@CS/PEG-DOX.	ferryl iron	146-151	progestagen associated endometrial protein	Homo sapiens	97-100
33855574-1	2020	A multielement preconcentration procedure based Fe3O4 magnetic nanoparticles coated with polythiophene(Fe3O4@PTh MNPs) as a solid phase was reported for Cu(II), Co(II), Cd(II), Ni(II) and Zn(II) ions.	ferryl iron	48-53	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	161-167
33855574-1	2020	A multielement preconcentration procedure based Fe3O4 magnetic nanoparticles coated with polythiophene(Fe3O4@PTh MNPs) as a solid phase was reported for Cu(II), Co(II), Cd(II), Ni(II) and Zn(II) ions.	ferryl iron	103-108	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	161-167
32175824-5	2020	In addition, the Fe3O4@CS/PEG-DOX exhibited excellent pH-sensitivity, 73.1% DOX was released within 48 h at pH 4.0.	ferryl iron	17-22	progestagen associated endometrial protein	Homo sapiens	26-29
32526844-4	2020	In this direction, a versatile synthesis of poly(styrene-block-acrylic acid) diblock copolymer/Fe3O4 magnetic nanocomposite (abbreviated as P(St-b-AAc)/Fe3O4)) was achieved for environmental applications, and particularly for the removal of antibiotic compounds.	ferryl iron	95-100	glycine-N-acyltransferase	Homo sapiens	147-150
32175824-6	2020	Furthermore, all the release behaviors fit the Higuchi model very well and the dissolution of CS/PEG layers played a key role on DOX release from Fe3O4@CS/PEG-DOX.	ferryl iron	146-151	progestagen associated endometrial protein	Homo sapiens	155-158
32175824-7	2020	The results of toxicity analysis in human liver hepatocellular carcinoma cells (HepG2) revealed that Fe3O4@CS/PEG-DOX exhibited high anti-tumor activity, while the Fe3O4@CS/PEG nanocomposites were practically non-toxic.	ferryl iron	164-169	progestagen associated endometrial protein	Homo sapiens	173-176
32175824-8	2020	Therefore, all the results demonstrated that the Fe3O4@CS/PEG-DOX could have an important impact on the development of targeted intracellular delivery nanodevices for cancer therapy.	ferryl iron	49-54	progestagen associated endometrial protein	Homo sapiens	58-61
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	46-52	PPARG coactivator 1 alpha	Homo sapiens	247-314
32061359-2	2020	Herein, a novel polyethylene glycol (PEG) modified magnetic covalent organic framework material based on the Schiff base reaction was prepared (PEG/Fe3O4@SNW-1).	ferryl iron	148-153	SNW domain containing 1	Homo sapiens	154-159
32061359-8	2020	These results indicated that the proposed method was feasible and demonstrated the potential application of the PEG/Fe3O4@SNW-1 material for detecting similar pesticide residues in environmental water samples.	ferryl iron	116-121	SNW domain containing 1	Homo sapiens	122-127
32330380-2	2020	Herein, we created a novel Fe3O4@polydopamine (PDA)@Bovine Serum Albumin (BSA)-Bi2S3 composite as a theranostic agent, by chemically-linking the Fe3O4@PDA with BSA-Bi2S3 via the amidation between the carboxyl groups of BSA and the amino groups of PDA.	ferryl iron	27-32	albumin	Homo sapiens	59-72
32330380-2	2020	Herein, we created a novel Fe3O4@polydopamine (PDA)@Bovine Serum Albumin (BSA)-Bi2S3 composite as a theranostic agent, by chemically-linking the Fe3O4@PDA with BSA-Bi2S3 via the amidation between the carboxyl groups of BSA and the amino groups of PDA.	ferryl iron	145-150	albumin	Homo sapiens	59-72
32185732-2	2020	Fe3O4/TiO2 synthesized by wet impregnation method with an additional reduction under H2 atmosphere was characterized by XRD, FTIR, BET, XPS, and VSM analysis.	ferryl iron	0-5	delta/notch like EGF repeat containing	Homo sapiens	131-134
31879118-1	2020	Herein, a novel nanocomposite (Fe3O4@TATS@ATA) was prepared and used for adsorptive removal of Pb(II) ions from aqueous environment.	ferryl iron	31-36	submaxillary gland androgen regulated protein 3B	Homo sapiens	95-101
31879118-2	2020	The magnetic nanocomposite (Fe3O4@TATS@ATA) was characterized using FTIR, TEM, SEM, EDX, element mapping analysis (EMA), TGA analysis, XRD patterns, VSM, BET analysis, XPS spectrum, and zeta potential.	ferryl iron	28-33	T-box transcription factor 1	Homo sapiens	121-124
31879118-2	2020	The magnetic nanocomposite (Fe3O4@TATS@ATA) was characterized using FTIR, TEM, SEM, EDX, element mapping analysis (EMA), TGA analysis, XRD patterns, VSM, BET analysis, XPS spectrum, and zeta potential.	ferryl iron	28-33	delta/notch like EGF repeat containing	Homo sapiens	154-157
31879118-4	2020	The BET surface area, average pore size, pore volume and magnetization saturation for Fe3O4@TATS@ATA were found to be 114 m2/g, 6.4 nm, 0.054 cm-3/g, and 22 emu/g, respectively.	ferryl iron	86-91	delta/notch like EGF repeat containing	Homo sapiens	4-7
31879118-5	2020	The adsorption isotherm data showed that Pb(II) adsorption onto Fe3O4@TATS@ATA fitted to Langmuir and Dubinin-Raduskevich isotherm model due to better R2 value which was greater than 0.9 and qm of Pb(II) was 205.2 mg/g at pH 5.7 in 150 min.	ferryl iron	64-69	submaxillary gland androgen regulated protein 3B	Homo sapiens	41-47
31879118-5	2020	The adsorption isotherm data showed that Pb(II) adsorption onto Fe3O4@TATS@ATA fitted to Langmuir and Dubinin-Raduskevich isotherm model due to better R2 value which was greater than 0.9 and qm of Pb(II) was 205.2 mg/g at pH 5.7 in 150 min.	ferryl iron	64-69	submaxillary gland androgen regulated protein 3B	Homo sapiens	197-203
31879118-6	2020	Adsorption kinetics data displayed that Pb(II) adsorption onto Fe3O4@TATS@ATA was fitted to the pseudo-second-order and Elovich kinetic models.	ferryl iron	63-68	submaxillary gland androgen regulated protein 3B	Homo sapiens	40-46
31879118-8	2020	Results showed that Fe3O4@TATS@ATA nanocomposite was promising material for efficient removal of toxic Pb(II) from aqueous environment.	ferryl iron	20-25	submaxillary gland androgen regulated protein 3B	Homo sapiens	103-109
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	46-52	PPARG coactivator 1 alpha	Homo sapiens	316-325
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	46-52	collapsin response mediator protein 1	Homo sapiens	473-477
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	46-52	mitofusin 2	Homo sapiens	482-486
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	58-64	PPARG coactivator 1 alpha	Homo sapiens	247-314
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	58-64	PPARG coactivator 1 alpha	Homo sapiens	316-325
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	58-64	collapsin response mediator protein 1	Homo sapiens	473-477
31922269-3	2020	In this study, we showed that PEG-COOH-coated Fe3 O4 (PEG-Fe3 O4 ) nanoparticles induced mitochondrial instability in dendritic cells (DCs) by impairing mitochondrial dynamics due to promotion of mitochondrial biogenesis through activation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) pathway, inhibiting mitochondrial degradation via decreased autophagy, and facilitating mitochondrial fragmentation involving increased levels of DRP1 and MFN2.	ferryl iron	58-64	mitofusin 2	Homo sapiens	482-486
31922269-4	2020	The resulting reduced levels of dextran uptake, CD80, CD86 and chemokine receptor 7 (CCR7) suggested that PEG-Fe3 O4 nanoparticles impaired the functionally immature state of DCs.	ferryl iron	110-116	C-C motif chemokine receptor 7	Homo sapiens	54-83
31922269-4	2020	The resulting reduced levels of dextran uptake, CD80, CD86 and chemokine receptor 7 (CCR7) suggested that PEG-Fe3 O4 nanoparticles impaired the functionally immature state of DCs.	ferryl iron	110-116	C-C motif chemokine receptor 7	Homo sapiens	85-89
32387943-7	2020	Furthermore, hAFP combined with chitosan magnetic (CS@Fe3O4) nanoparticles or vacuum impregnation hAFP was shown to be an effective method to reduce the mechanical damage of ice crystals to samples, and decrease the oxidation degree of samples during F-T cycles.	ferryl iron	54-59	alpha fetoprotein	Homo sapiens	13-17
31635659-5	2020	In the optimal conditions, the GCE/RGO/MWCNT-Fe3O4 electrode showed a wide linear range (0.15-220 muM), low limit of detection (LOD) (0.75 muM), and high sensitivity (2.868 muA muM-1 cm-2).	ferryl iron	45-50	PWWP domain containing 3A, DNA repair factor	Homo sapiens	177-182
31635639-3	2020	Fe2O3/Fe3O4 heterogeneous microparticles calcined at 200  C for 1 h with absolute ethyl alcohol of 20 mL had the largest saturation magnetization of 90.1 Am2/kg.	ferryl iron	6-11	adrenomedullin 2	Homo sapiens	154-157
32314062-1	2020	beta-Cyclodextrin-functionalized magnetic covalent organic framework (Fe3O4@COF@Au-beta-CD) was developed as sorbent for magnetic solid phase extraction of trace sulfonamides in meat samples prior to HPLC-MS/MS analysis.	ferryl iron	70-75	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	83-90
31927189-0	2020	An ultrasensitive immunosensor based on manganese dioxide-graphene nanoplatelets and core shell Fe3O4@Au nanoparticles for label-free detection of carcinoembryonic antigen.	ferryl iron	96-101	CEA cell adhesion molecule 3	Homo sapiens	147-171
32608680-3	2020	The effects of Fe3O4-CuO catalyst loading, SPC concentration, pH value, and common chloride ions on AO7 degradation in the Fe3O4-CuO/SPC system were evaluated.	ferryl iron	123-128	urocortin 3	Homo sapiens	133-136
32608680-5	2020	The results show that Fe3O4-CuO could effectively activate SPC to degrade AO7 and the reaction was accelerated with the increase of Fe3O4-CuO dosage.	ferryl iron	22-27	urocortin 3	Homo sapiens	59-62
32608680-5	2020	The results show that Fe3O4-CuO could effectively activate SPC to degrade AO7 and the reaction was accelerated with the increase of Fe3O4-CuO dosage.	ferryl iron	132-137	urocortin 3	Homo sapiens	59-62
32608680-10	2020	The Fe3O4-CuO/SPC system achieved a high mineralization rate in the process of decolorization of AO7.	ferryl iron	4-9	urocortin 3	Homo sapiens	14-17
31791860-3	2020	Based on synergic effects of these strategies, Fe3O4@TMU-32 nanocomposite shows very high capacity toward Hg(II) and Pb(II) metal ions.	ferryl iron	47-52	submaxillary gland androgen regulated protein 3B	Homo sapiens	117-123
31791860-8	2020	Fe3O4@TMU-32 nanocomposite shows improved removal capacity (45 % and 54 % toward Pb(II) and Hg(II)) rather pristine TMU-32 framework because of urea decorated framework and charge modulated surface.	ferryl iron	0-5	submaxillary gland androgen regulated protein 3B	Homo sapiens	81-98
32337443-0	2020	Preparation of Fe3O4@SiO2@ P(AANa-co-AM) Composites and Their Adsorption for Pb(II).	ferryl iron	15-20	submaxillary gland androgen regulated protein 3B	Homo sapiens	77-83
32337443-5	2020	The adsorption kinetics and isotherms model of Pb(II) on the Fe3O4@SiO2@P(AANa-co-AM) composites followed a pseudo-second-order model and the Langmuir isotherm model, respectively.	ferryl iron	61-66	submaxillary gland androgen regulated protein 3B	Homo sapiens	47-53
32337443-7	2020	The thermodynamic study of adsorption showed that the adsorption of Pb(II) on Fe3O4@SiO2@P(AANa-co-AM) composites was a spontaneous endothermic process.	ferryl iron	78-83	submaxillary gland androgen regulated protein 3B	Homo sapiens	68-74
31791860-9	2020	Fe3O4@TMU-32 nanocomposite adsorb 1600 mg.g-1 of Pb(II) and 905 mg.g-1 of Hg(II) which extremely rare in the literature.	ferryl iron	0-5	submaxillary gland androgen regulated protein 3B	Homo sapiens	49-55
31791860-10	2020	Such improvement can be related to the electrostatic interaction between cationic nature of Pb(II) and Hg(II) and negative charge of the Fe3O4@TMU-32 adsorbent.	ferryl iron	137-142	submaxillary gland androgen regulated protein 3B	Homo sapiens	92-98
31927189-2	2020	The designed immunosensor was based on CEA antibody (anti-CEA) anchored with core shell Fe3O4@Au nanoparticles which were immobilized on a screen-printed carbon electrode modified with manganese dioxide decorating on graphene nanoplatelets (SPCE/GNP-MnO2/Fe3O4@Au-antiCEA).	ferryl iron	88-93	CEA cell adhesion molecule 3	Homo sapiens	58-61
31975003-3	2020	The results show that Fe3O4 nanoparticles can be well dispersed on NI/S flakes and the hydrolyzed APTES molecules can simultaneously bond to the hydroxyl groups of Fe3O4 and NI/S.	ferryl iron	22-27	solute carrier family 5 member 5	Homo sapiens	67-71
31975003-3	2020	The results show that Fe3O4 nanoparticles can be well dispersed on NI/S flakes and the hydrolyzed APTES molecules can simultaneously bond to the hydroxyl groups of Fe3O4 and NI/S.	ferryl iron	22-27	solute carrier family 5 member 5	Homo sapiens	174-178
31917217-2	2020	The fabricated nanocomposite (CTM@Fe3O4) is characterized using FTIR, TGA, BET, XRD, Raman, XPS, FESEM, and HRTEM techniques.	ferryl iron	34-39	T-box transcription factor 1	Homo sapiens	70-73
31975003-4	2020	Due to the synergetic effect, magnetic NI/S composite can graft more amount of APTES molecules rather than Fe3O4 nanoparticles or NI/S alone.	ferryl iron	107-112	solute carrier family 5 member 5	Homo sapiens	39-43
31975003-5	2020	When the mass ratio of NI/S:Fe3O4 is 1:1, the saturation magnetization of AMNI/S-1 is 17.4 emu/g, facilitating the efficient magnetic separation in aqueous solution.	ferryl iron	28-33	solute carrier family 5 member 5	Homo sapiens	23-27
31975003-10	2020	The mechanism for the adsorption of Pb(II) ions onto AMNI/S-1 is due to the surface complexation of Fe3O4 and NI/S, and the chelation of amine groups (-NH2).	ferryl iron	100-105	submaxillary gland androgen regulated protein 3B	Homo sapiens	36-42
31975003-10	2020	The mechanism for the adsorption of Pb(II) ions onto AMNI/S-1 is due to the surface complexation of Fe3O4 and NI/S, and the chelation of amine groups (-NH2).	ferryl iron	100-105	solute carrier family 5 member 5	Homo sapiens	55-59
31917990-0	2020	Synthesis of multi-functionalized Fe3O4-NH2-SH nanofiber based on chitosan for single and simultaneous adsorption of Pb(II) and Ni(II) from aqueous system.	ferryl iron	34-39	submaxillary gland androgen regulated protein 3B	Homo sapiens	117-123
31828877-3	2020	For this purpose, biotinilated-anti-prostate-specific antigen (PSA) antibody was bioconjugated with iron oxide magnetic nanoparticles (Fe3 O4 ) and drop-casted on the surface of glassy carbon electrode (GCE).	ferryl iron	135-141	aminopeptidase puromycin sensitive	Homo sapiens	18-67
32115941-5	2020	As a result, the in situ-activated, Ni/Cr-doped Fe3O4 electrocatalyst exhibits an outstanding OER performance with a small overpotential of 262 mV to reach 10 mA cm-2, a low Tafel slope of 35.0 mV dec-1, and excellent long-term stability of 120 h, among the best spinel Fe-rich OER electrocatalysts.	ferryl iron	48-53	deleted in esophageal cancer 1	Homo sapiens	197-202
31917217-2	2020	The fabricated nanocomposite (CTM@Fe3O4) is characterized using FTIR, TGA, BET, XRD, Raman, XPS, FESEM, and HRTEM techniques.	ferryl iron	34-39	delta/notch like EGF repeat containing	Homo sapiens	75-78
32521928-7	2020	CONCLUSIONS: Fe3O4 core Ag (Au) shell induced apoptosis on cancer cells (HCT116 and HUH7) via the p53/bcl-2/casp-3 pathway.	ferryl iron	13-18	MIR7-3 host gene	Homo sapiens	84-88
32170399-1	2020	Synthesis and functionalization of magnetite nanoparticles (Fe3O4) was achieved with the view to covalently bind both cholesterol oxidase and cholesterol esterase biorecognition agents for the development of free and total cholesterol biosensors.	ferryl iron	60-65	carboxyl ester lipase	Homo sapiens	142-162
32170399-7	2020	Graphical abstract Schematic representation of cholesterol esterase and oxidase loaded magnetic nanoparticles (Fe3O4@APTES or Fe3O4@APTES-PAMAM) generating hydrogen peroxide from cholesterol palmitate.	ferryl iron	111-116	carboxyl ester lipase	Homo sapiens	47-67
32170399-7	2020	Graphical abstract Schematic representation of cholesterol esterase and oxidase loaded magnetic nanoparticles (Fe3O4@APTES or Fe3O4@APTES-PAMAM) generating hydrogen peroxide from cholesterol palmitate.	ferryl iron	126-131	carboxyl ester lipase	Homo sapiens	47-67
31924030-2	2020	Fe3O4@SiO2 magnetic nanoparticles, were grafted with polymer brushes consisting of poly (NIPAM-co-GMA) (PNG) chains via surface initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization.	ferryl iron	0-5	myelin associated glycoprotein	Homo sapiens	98-101
32521928-7	2020	CONCLUSIONS: Fe3O4 core Ag (Au) shell induced apoptosis on cancer cells (HCT116 and HUH7) via the p53/bcl-2/casp-3 pathway.	ferryl iron	13-18	transformation related protein 53, pseudogene	Mus musculus	98-101
32521928-7	2020	CONCLUSIONS: Fe3O4 core Ag (Au) shell induced apoptosis on cancer cells (HCT116 and HUH7) via the p53/bcl-2/casp-3 pathway.	ferryl iron	13-18	B cell leukemia/lymphoma 2	Mus musculus	102-107
32521928-7	2020	CONCLUSIONS: Fe3O4 core Ag (Au) shell induced apoptosis on cancer cells (HCT116 and HUH7) via the p53/bcl-2/casp-3 pathway.	ferryl iron	13-18	caspase 3	Mus musculus	108-114
32376536-0	2020	[Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promotes M1 polarization of tumorassociated macrophages in mice].	ferryl iron	32-37	mannose receptor, C type 1	Mus musculus	6-11
31933263-9	2020	In addition, the amount of ROS production and caspase-3 activity increased in the treated cells with Fe3O4@CPTMOS/TP NPs.	ferryl iron	101-106	caspase 3	Mus musculus	46-55
31669845-11	2020	Ultimately, trastuzumab (anti HER-2) antibody has been used to test the performance of the prepared Fe3O4@Pd/CaCO3-DTT NPs in a real protein reduction reaction.	ferryl iron	100-105	erb-b2 receptor tyrosine kinase 2	Homo sapiens	30-35
31933263-6	2020	Moreover, apoptosis induced by Fe3O4@CPTMOS/TP NPs was assessed by Hoechst 33432 staining, oxygen activity specification evaluation, caspase-3 activity assay, cell cycle analysis and annexin V/PI staining followed by flow cytometry analysis.	ferryl iron	31-36	caspase 3	Mus musculus	133-142
31933263-6	2020	Moreover, apoptosis induced by Fe3O4@CPTMOS/TP NPs was assessed by Hoechst 33432 staining, oxygen activity specification evaluation, caspase-3 activity assay, cell cycle analysis and annexin V/PI staining followed by flow cytometry analysis.	ferryl iron	31-36	annexin A5	Mus musculus	183-192
31892093-3	2020	Up addition of PSA, Fe3O4-labeled DNAzyme-peptide probe was cleaved, followed by the magnetic separation.	ferryl iron	20-25	kallikrein related peptidase 3	Homo sapiens	15-18
32376536-2	2020	METHODS: Anti-CD206 antibody-conjugated Fe3O4-based polylactic acid glycolic acid (CD206- Fe3O4-PLGA) nanoparticles were prepared with the W/O/W method.	ferryl iron	40-45	mannose receptor, C type 1	Mus musculus	14-19
32376536-2	2020	METHODS: Anti-CD206 antibody-conjugated Fe3O4-based polylactic acid glycolic acid (CD206- Fe3O4-PLGA) nanoparticles were prepared with the W/O/W method.	ferryl iron	40-45	mannose receptor, C type 1	Mus musculus	83-88
31887953-1	2020	Herein, we report a novel magnetic bifunctional beta-cyclodextrin nanocomposite (Fe3O4@beta-CD-CDI) based on metal coordination, which may be used for adsorption and degradation of persistent organic pollutants in aqueous solution.	ferryl iron	81-86	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	87-94
31972945-4	2020	Among the three Mg/Al ratios, the calcined Fe3O4@4:1 Mg/Al LDH exhibited excellent performance for iodide removal with 105.04 mg/g of the maximum iodide adsorption capacity due to its wide interlayer spacing and largest BET surface area.	ferryl iron	43-48	delta/notch like EGF repeat containing	Homo sapiens	220-223
31726443-6	2020	AFP-specific ssDNA aptamer was grafted to the magnetic nanoparticles (Fe3O4@SiO2) via avidin-biotin interaction, and the resultant aptamer functionalized magnetic nanoparticles (Ap-MNPs) were adequately characterized and tested.	ferryl iron	70-75	alpha fetoprotein	Homo sapiens	0-3
32009138-1	2020	We report a large amplification of surface plasmon signals for a double hybridization microarray chip assembly that bridges localized gold and detection probe-carrying-core/shell Fe3O4@Au nanoparticles for detection of as low as 80 aM miRNA-155 marker in solution.	ferryl iron	179-184	microRNA 155	Homo sapiens	235-244
31887953-3	2020	The results of kinetic and isothermal adsorption model investigation indicated that the adsorption rate and capacity of Fe3O4@beta-CD-CDI were better than other materials, suggesting the effective accessibility of adsorption sites.	ferryl iron	120-125	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	126-133
31887953-4	2020	We further confirmed that Fe3O4@beta-CD-CDI can be used as heterogeneous catalyst to remove BPA through Fenton-like reaction in the presence of hydrogen peroxide (H2O2).	ferryl iron	26-31	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	32-39
31887953-6	2020	This study indicated that the magnetic Fe3O4@beta-CD-CDI material has great potential applications in wastewater purification containing persistent organic pollutants.	ferryl iron	39-44	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	45-52
31708258-5	2020	FINDINGS: It has been found that the optimal condition for fabricating this NCA/OA/Fe3O4 aerogel is 0.4 wt% nanocellulose, 3 mg mL-1 OA and 0.5 wt% Fe3O4 in the aqueous solution.	ferryl iron	83-88	CEA cell adhesion molecule 4	Homo sapiens	76-79
31708258-5	2020	FINDINGS: It has been found that the optimal condition for fabricating this NCA/OA/Fe3O4 aerogel is 0.4 wt% nanocellulose, 3 mg mL-1 OA and 0.5 wt% Fe3O4 in the aqueous solution.	ferryl iron	148-153	CEA cell adhesion molecule 4	Homo sapiens	76-79
31708258-8	2020	As a consequence, this hydrophobic magnetic NCA/OA/Fe3O4 aerogel is promising not only for easy oil and organic solvent adsorption but also potentially for other magnetic related applications.	ferryl iron	51-56	CEA cell adhesion molecule 4	Homo sapiens	44-47
31967178-5	2020	The extremely abundant amine groups of PAMAM-PMAA brushes and superparamagnetism of the Fe3O4 core endowed the composite nanospheres with high detection sensitivity (1 fmol muL-1), excellent selectivity (1 : 500 molar ratios of beta-casein/BSA) and high recyclability (five cycles) towards phosphopeptides.	ferryl iron	88-93	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	173-178
31683438-1	2020	In this paper, a novel electrode named 2.5D Ti/Sb-SnO2/PANI was developed by magnetically in-situ integration of adsorbent and electrocatalyst, where the green synthetic Fe3O4/polyaniline (PANI) nanoparticles with fair adsorption capability were used as auxiliary electrodes and coated on the surface of Ti/Sb-SnO2 main electrode, to enrich the pollutants in the vicinity of anode and therefore boost the electrochemical oxidation (EO) efficiency.	ferryl iron	170-175	strawberry notch homolog 2	Homo sapiens	50-53
32194835-7	2020	In vitro experiments demonstrate that LDH-Fe3O4-HA/DOX nanohybrids are able to specifically target B16 cells overexpressing CD44 receptors and effectively release DOX to nucleus.	ferryl iron	42-47	CD44 antigen	Mus musculus	124-128
32194835-9	2020	Conclusion: The designed LDH-Fe3O4-HA/DOX nanohybrids may be developed as a novel targeted theranostic nanoplatform for enhanced T1 -weighted MR imaging-guided chemotherapy of CD44 receptor-overexpressing tumors.	ferryl iron	29-34	CD44 antigen	Mus musculus	176-180
31883592-3	2020	To construct such a versatile platform, the model analyte, carcinoembryonic antigen (CEA), was captured by magnetic Fe3O4 nanoparticles bound with primary antibodies (Fe3O4-Ab1) and then recognized by the detection antibodies conjugated complex containing poly(amidoamine) (PAMAM), carbon nanotube (CNT) and carboxyl functionalized CdSe nanocrystals (NCs) (CNT-PAMAM-CdSe NCs-Ab2).	ferryl iron	116-121	CEA cell adhesion molecule 3	Homo sapiens	59-83
31883592-3	2020	To construct such a versatile platform, the model analyte, carcinoembryonic antigen (CEA), was captured by magnetic Fe3O4 nanoparticles bound with primary antibodies (Fe3O4-Ab1) and then recognized by the detection antibodies conjugated complex containing poly(amidoamine) (PAMAM), carbon nanotube (CNT) and carboxyl functionalized CdSe nanocrystals (NCs) (CNT-PAMAM-CdSe NCs-Ab2).	ferryl iron	116-121	CEA cell adhesion molecule 3	Homo sapiens	85-88
31726600-7	2020	Because of the good performance observed in the water matrices of tap water and the Songhua River, these results demonstrate the potential application of the Fe3O4/PS/MW system for wastewater treatment.	ferryl iron	158-163	nuclear RNA export factor 1	Homo sapiens	66-69
31683438-1	2020	In this paper, a novel electrode named 2.5D Ti/Sb-SnO2/PANI was developed by magnetically in-situ integration of adsorbent and electrocatalyst, where the green synthetic Fe3O4/polyaniline (PANI) nanoparticles with fair adsorption capability were used as auxiliary electrodes and coated on the surface of Ti/Sb-SnO2 main electrode, to enrich the pollutants in the vicinity of anode and therefore boost the electrochemical oxidation (EO) efficiency.	ferryl iron	170-175	strawberry notch homolog 2	Homo sapiens	310-313
31630253-11	2020	The expression of Bax increased 1.62-fold, while the expression of Bcl-2 decreased 0.76-fold at 135.6 microM/mL concentration of Fe3O4@Glu/PTSC compared to untreated A549 cells.	ferryl iron	129-134	BCL2 associated X, apoptosis regulator	Homo sapiens	18-21
31845242-3	2020	EPS/Fe3O4 exhibited the adsorption performance of 77.93%, 74.13%, 65.62%, and 56.64% for SMX, SM1, SM2 and SDZ, respectively, increased by 7.93%, 19.02%, 13.78% and 9.93% compared to traditional EPS.	ferryl iron	4-9	SM1	Homo sapiens	94-97
31845242-3	2020	EPS/Fe3O4 exhibited the adsorption performance of 77.93%, 74.13%, 65.62%, and 56.64% for SMX, SM1, SM2 and SDZ, respectively, increased by 7.93%, 19.02%, 13.78% and 9.93% compared to traditional EPS.	ferryl iron	4-9	SM2	Homo sapiens	99-102
31845242-2	2020	This study reported eco-friendly and reusable EPS/Fe3O4 was applied in the sulfonamide-contaminated water treatment, including sulfamethoxazole (SMX), sulfamerazine (SM1), sulfamethazine (SM2) and sulfadiazine (SDZ), respectively.	ferryl iron	50-55	SM2	Homo sapiens	188-191
31630253-11	2020	The expression of Bax increased 1.62-fold, while the expression of Bcl-2 decreased 0.76-fold at 135.6 microM/mL concentration of Fe3O4@Glu/PTSC compared to untreated A549 cells.	ferryl iron	129-134	BCL2 apoptosis regulator	Homo sapiens	67-72
31630253-12	2020	Furthermore, the Fe3O4@Glu/PTSC nanoparticulate-inducing apoptosis properties were evaluated by Hoechst 33258 staining, Caspase-3 activation assay and Annexin V/propidium iodide staining.	ferryl iron	17-22	caspase 3	Homo sapiens	120-129
31630253-12	2020	Furthermore, the Fe3O4@Glu/PTSC nanoparticulate-inducing apoptosis properties were evaluated by Hoechst 33258 staining, Caspase-3 activation assay and Annexin V/propidium iodide staining.	ferryl iron	17-22	annexin A5	Homo sapiens	151-160
31909611-3	2020	As intended, these new azole-triazole ligands provide lower field strengths, resulting in high-spin (HS) [FeII(L4NMeIm)3](BF4)2 (1 4H2O) and spin crossover (SCO) active [FeII(L4SIm)3](BF4)2 (2 0.5H2O).	ferryl iron	169-189	spindlin 1	Rattus norvegicus	95-99
31862051-1	2020	In this study, we report a novel magnetic biomimetic nanozyme (Fe3O4@Cu/GMP (guanosine 5"-monophosphate)) with high laccase-like activity, which could oxidize toxic o-phenylenediamine (OPD) and remove phenolic compounds.	ferryl iron	63-68	5'-nucleotidase, cytosolic II	Homo sapiens	72-75
31862051-2	2020	The magnetic laccase-like nanozyme was readily obtained via complexed Cu2+ and GMP that grew on the surface of magnetic Fe3O4 nanoparticles.	ferryl iron	120-125	5'-nucleotidase, cytosolic II	Homo sapiens	79-82
31862051-3	2020	The prepared Fe3O4@Cu/GMP catalyst could be magnetically recycled for at least five cycles while still retaining above 70% activity.	ferryl iron	13-18	5'-nucleotidase, cytosolic II	Homo sapiens	22-25
31862051-4	2020	As a laccase mimic, Fe3O4@Cu/GMP had more activity and robust stability than natural laccase for the oxidization of OPD.	ferryl iron	20-25	5'-nucleotidase, cytosolic II	Homo sapiens	29-32
31862051-5	2020	Fe3O4@Cu/GMP retained about 90% residual activity at 90 C and showed little change at pH 3-9, and the nanozyme kept its excellent activity after long-term storage.	ferryl iron	0-5	5'-nucleotidase, cytosolic II	Homo sapiens	9-12
31862051-6	2020	Meanwhile, Fe3O4@Cu/GMP had better activity for removing phenolic compounds, and the removal of naphthol was more than 95%.	ferryl iron	11-16	5'-nucleotidase, cytosolic II	Homo sapiens	20-23
31862051-7	2020	Consequently, the proposed Fe3O4@Cu/GMP nanozyme shows potential for use as a robust catalyst for applications in environmental remediation.	ferryl iron	27-32	5'-nucleotidase, cytosolic II	Homo sapiens	36-39
31992134-0	2020	RF hyperthermia by encapsulated Fe3O4 nanoparticles induces cancer cell death via time-dependent caspase-3 activation.	ferryl iron	32-37	caspase 3	Homo sapiens	97-106
31653472-1	2020	In this work, poly(dopamine)-coated magnetic nanoparticles (Fe3O4@pDA) have been used as sorbents for the magnetic dispersive solid-phase extraction (m-dSPE) of a group of 10 phthalic acid esters (dipropyl phthalate, DPP, dibutyl phthalate, DBP, dicyclohexyl phthalate, DCHP, bis(2-ethylhexyl)phthalate, DEHP, di-n-octyl phthalate, DNOP, diisodecyl phthalate, DIDP, butylbenzyl phthalate, BBP, diisononyl phthalate, DINP, diisopentyl phthalate, DIPP, di-n-pentyl phthalate, DNPP) and one adipate (di(2-ethylhexyl) adipate, DEHA) from sea water and sea sand extracts employing DBP-d4 and DHP-d4 as internal standards.	ferryl iron	60-65	D-box binding PAR bZIP transcription factor	Homo sapiens	241-244
31653472-1	2020	In this work, poly(dopamine)-coated magnetic nanoparticles (Fe3O4@pDA) have been used as sorbents for the magnetic dispersive solid-phase extraction (m-dSPE) of a group of 10 phthalic acid esters (dipropyl phthalate, DPP, dibutyl phthalate, DBP, dicyclohexyl phthalate, DCHP, bis(2-ethylhexyl)phthalate, DEHP, di-n-octyl phthalate, DNOP, diisodecyl phthalate, DIDP, butylbenzyl phthalate, BBP, diisononyl phthalate, DINP, diisopentyl phthalate, DIPP, di-n-pentyl phthalate, DNPP) and one adipate (di(2-ethylhexyl) adipate, DEHA) from sea water and sea sand extracts employing DBP-d4 and DHP-d4 as internal standards.	ferryl iron	60-65	transmembrane protein 158	Homo sapiens	389-392
31653472-1	2020	In this work, poly(dopamine)-coated magnetic nanoparticles (Fe3O4@pDA) have been used as sorbents for the magnetic dispersive solid-phase extraction (m-dSPE) of a group of 10 phthalic acid esters (dipropyl phthalate, DPP, dibutyl phthalate, DBP, dicyclohexyl phthalate, DCHP, bis(2-ethylhexyl)phthalate, DEHP, di-n-octyl phthalate, DNOP, diisodecyl phthalate, DIDP, butylbenzyl phthalate, BBP, diisononyl phthalate, DINP, diisopentyl phthalate, DIPP, di-n-pentyl phthalate, DNPP) and one adipate (di(2-ethylhexyl) adipate, DEHA) from sea water and sea sand extracts employing DBP-d4 and DHP-d4 as internal standards.	ferryl iron	60-65	D-box binding PAR bZIP transcription factor	Homo sapiens	576-579
31991558-1	2020	This study explored the feasibility of utilizing a novel sorbent humic acid (HA) coated Fe3O4/attapulgite (MATP) magnetic nanoparticles (HMATP) for the sorption of propranolol from aqueous solutions.	ferryl iron	88-93	solute carrier family 45 member 2	Homo sapiens	107-111
31678824-0	2020	Personalized detection of circling exosomal PD-L1 based on Fe3O4@TiO2 isolation and SERS immunoassay.	ferryl iron	59-64	CD274 molecule	Homo sapiens	44-49
32009981-0	2019	Fe3O4 Nanoparticles Attenuated Salmonella Infection in Chicken Liver Through Reactive Oxygen and Autophagy via PI3K/Akt/mTOR Signaling.	ferryl iron	0-5	mechanistic target of rapamycin	Gallus gallus	120-124
31664285-0	2020	Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-kappaB and TGF-beta signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.	ferryl iron	25-30	nuclear factor kappa B subunit 1	Homo sapiens	72-81
31678874-2	2020	In the present study, flower-like molybdenum disulfide decorated with iron oxide nanoparticles (MoS2/Fe3O4) is designed via a two-step hydrothermal method and mainly applied in the removal of Hg(II) and Pb(II) ions in aqueous environment.	ferryl iron	101-106	submaxillary gland androgen regulated protein 3B	Homo sapiens	203-209
31678874-4	2020	Batch adsorption experiments show that the obtained MoS2/Fe3O4 nanohybrid enables efficient capture of Hg(II) and Pb(II) ions, accompanied by ease-of-separation from solution by simply applying a magnet.	ferryl iron	57-62	submaxillary gland androgen regulated protein 3B	Homo sapiens	114-120
31678874-8	2020	Practical application potential of magnetic MoS2/Fe3O4 nanohybrid in realistic lead-acid battery industry wastewater and Pb(II)-contaminated soil is further explored, achieving promising results with high Pb(II) removal efficiency of 99.63% for wastewater and 57.15% for soil.	ferryl iron	49-54	submaxillary gland androgen regulated protein 3B	Homo sapiens	205-211
31897844-1	2020	A fluorescent nanoprobe for Pb(II) has been developed by employing aptamer-functionalized upconversion nanoparticles (UCNPs) and magnetic Fe3O4-modified (MNPs) gold nanoparticles (GNPs).	ferryl iron	138-143	submaxillary gland androgen regulated protein 3B	Homo sapiens	28-34
31664285-0	2020	Polyethyleneimine coated Fe3O4 magnetic nanoparticles induce autophagy, NF-kappaB and TGF-beta signaling pathway activation in HeLa cervical carcinoma cells via reactive oxygen species generation.	ferryl iron	25-30	transforming growth factor alpha	Homo sapiens	86-94
31196271-0	2019	Fabrication of Magnetic Fe3O4 Nanoparticles with Unidirectional Extension Pattern by a Facile and Eco-Friendly Microwave-Assisted Solvothermal Method.	ferryl iron	24-29	ciliogenesis associated kinase 1	Homo sapiens	98-101
31718892-2	2020	METHODS: In this study, a pH-responsive DMSA-Fe3O4 magnetic nanoparticles (MNPs) covalently connect with ADM and As2O3 as a drug delivery system was invented to discuss the anticancer efficacy in non-Hodgkin"s lymphoma (NHL) cell line--Raji.	ferryl iron	45-50	adrenomedullin	Homo sapiens	105-108
32003667-5	2020	In this regard, all the essential structural analyses such as FT-IR, EDX, VSM, and TGA have been performed on the Fe3O4/P4VP-Pd catalytic system to investigate its properties.	ferryl iron	114-119	T-box transcription factor 1	Homo sapiens	83-86
31746398-3	2020	The present study aimed to investigate the potential antifibrotic activity of CTGF small interfering RNA (siRNA) mediated by polyethyleneimine (PEI)-functionalized magnetic iron oxide (Fe3O4) nanoparticles (NPs) in LX-2 cells.	ferryl iron	185-190	cellular communication network factor 2	Homo sapiens	78-82
31746398-9	2020	These results indicated that CTGF siRNA delivered by PEI-Fe3O4 NPs significantly reduces CTGF expression and collagen production in activated LX-2 cells, providing a basis for future in vivo studies.	ferryl iron	57-62	cellular communication network factor 2	Homo sapiens	29-33
31746398-9	2020	These results indicated that CTGF siRNA delivered by PEI-Fe3O4 NPs significantly reduces CTGF expression and collagen production in activated LX-2 cells, providing a basis for future in vivo studies.	ferryl iron	57-62	cellular communication network factor 2	Homo sapiens	89-93
31335223-6	2020	The early and late apoptotic cells were detected by Annexin V-FITC/PI assay using IC30 concentration of Fe3O4 nanopowders.	ferryl iron	104-109	annexin A5	Mus musculus	52-61
31335223-8	2020	The apoptotic index of A549 cells was investigated and found out to increase by IC30 value of Fe3O4 nanopowders using TUNEL, BrdU, Bcl-2 immunocytochemical assays.	ferryl iron	94-99	B cell leukemia/lymphoma 2	Mus musculus	131-136
31622846-0	2020	AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe3O4 nanoparticles during oxidant-induced senescence in human fibroblasts.	ferryl iron	84-89	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	0-4
31514881-3	2020	The combination of MON-NH2 shell and magnetic Fe3O4 core provided a fast extraction of BPA, 4-alpha-CP, 4-t-OP and 4-NP from matrix solution.	ferryl iron	46-51	NADH:ubiquinone oxidoreductase subunit AB1	Homo sapiens	94-102
31514891-0	2020	Fe3O4@Au nanoparticles-based magnetoplatform for the HMGA maize endogenous gene electrochemical genosensing.	ferryl iron	0-5	HMG-Y-related protein A	Zea mays	53-57
31514891-2	2020	Superparamagnetic core-shell Fe3O4@Au nanoparticles (10.4 +- 1.7 nm) were used to assemble the genoassay through the covalent immobilization of HMGA DNA probes onto carboxylated self-assembled monolayers at the nanoparticles surface.	ferryl iron	29-34	HMG-Y-related protein A	Zea mays	144-148
31736309-2	2019	Herein, we constructed a dual-mode antifouling electrochemical sensing platform for the detection of prostate-specific antigen (PSA) based on two kinds of antifouling peptides functionalized with graphene oxide-Fe3O4-thionine (GO-Fe3O4-Thi) probe and internal reference Ferrocene (Fc), respectively.	ferryl iron	227-235	kallikrein related peptidase 3	Homo sapiens	101-132
31736309-3	2019	The longer peptide (Pep1) modified with GO-Fe3O4-Thi probe was designed to contain a peptide sequence (HSSKLQK) capable of being recognized and cut by PSA.	ferryl iron	40-48	kallikrein related peptidase 3	Homo sapiens	151-154
31736309-5	2019	The concentration of PSA can be measured through both the increase of differential pulse voltammetry (DPV) signal change of Thi and the decrease of chronoamperometry (CA) signal of the reduction of H2O2 electrocatalyzed by GO-Fe3O4.	ferryl iron	223-231	kallikrein related peptidase 3	Homo sapiens	21-24
31718134-4	2019	Moreover, the HA-BP Fe3O4 magnetic hydrogel demonstrates heat-generation characterization under an alternating magnetic field.	ferryl iron	20-25	hyaluronan binding protein 2	Homo sapiens	14-19
31718134-5	2019	The animal experiments confirm the biocompatibilities of HA-BP Fe3O4 hydrogel which presents the hydrogels potential for tissue regeneration and anti-cancer treatment applications.	ferryl iron	63-68	hyaluronan binding protein 2	Homo sapiens	57-62
31824157-0	2019	Preparation and Characterization of Fe3O4@MTX Magnetic Nanoparticles for Thermochemotherapy of Primary Central Nervous System Lymphoma in vitro and in vivo.	ferryl iron	36-41	metaxin 1	Homo sapiens	42-45
31824157-8	2019	Results: In vitro, compared with chemotherapy alone, apoptosis rate of Fe3O4@MTX mediated thermochemotherapy group was significantly increased, and expression of apoptosis-inducing gene Caspase-3 and Bax were significantly upregulated in OCI-LY18 cells, while expression of apoptosis-inhibiting Bcl-2 gene was significantly downregulated.	ferryl iron	71-76	metaxin 1	Homo sapiens	77-80
31824157-8	2019	Results: In vitro, compared with chemotherapy alone, apoptosis rate of Fe3O4@MTX mediated thermochemotherapy group was significantly increased, and expression of apoptosis-inducing gene Caspase-3 and Bax were significantly upregulated in OCI-LY18 cells, while expression of apoptosis-inhibiting Bcl-2 gene was significantly downregulated.	ferryl iron	71-76	BCL2 apoptosis regulator	Homo sapiens	295-300
31824157-12	2019	Conclusion: These results demonstrated in vivo and in vitro that the combined thermochemotherapy of Fe3O4@MTX MNPs was superior to the single MTX chemotherapy with less dosage, which may promote apoptosis of DLBCL cells through the mitochondrial apoptotic pathway and provided a new way for the treatment of PCNSL.	ferryl iron	100-105	metaxin 1	Homo sapiens	106-109
30873875-4	2019	First, the atom transfer radical polymerization (ATRP) of styrene was performed using an ATRP initiator attached to the surface of Fe3O4 nanoparticles, followed by functionalization of the Fe3O4-PSt with amine groups (-NH2).	ferryl iron	189-194	sulfotransferase family 1A member 1	Homo sapiens	195-198
31612334-0	2019	Immobilization of lactoperoxidase on Fe3O4 magnetic nanoparticles with improved stability.	ferryl iron	37-42	lactoperoxidase	Homo sapiens	18-33
31612334-1	2019	OBJECTIVE: The study aimed to develop a facile and effectual method to increase the stability of lactoperoxidase (LPO) by using its immobilization on Fe3O4 magnetic nanoparticles (Fe3O4 MNPs).	ferryl iron	150-155	lactoperoxidase	Homo sapiens	97-112
31612334-1	2019	OBJECTIVE: The study aimed to develop a facile and effectual method to increase the stability of lactoperoxidase (LPO) by using its immobilization on Fe3O4 magnetic nanoparticles (Fe3O4 MNPs).	ferryl iron	150-155	lactoperoxidase	Homo sapiens	114-117
31612334-1	2019	OBJECTIVE: The study aimed to develop a facile and effectual method to increase the stability of lactoperoxidase (LPO) by using its immobilization on Fe3O4 magnetic nanoparticles (Fe3O4 MNPs).	ferryl iron	180-185	lactoperoxidase	Homo sapiens	97-112
31612334-1	2019	OBJECTIVE: The study aimed to develop a facile and effectual method to increase the stability of lactoperoxidase (LPO) by using its immobilization on Fe3O4 magnetic nanoparticles (Fe3O4 MNPs).	ferryl iron	180-185	lactoperoxidase	Homo sapiens	114-117
31612334-2	2019	RESULTS: The successful immobilization of LPO on Fe3O4 MNPs was confirmed by using Fourier transform infrared spectroscopy (FT-IR) and field emission scanning electron microscopy (FE-SEM).	ferryl iron	49-54	lactoperoxidase	Homo sapiens	42-45
31612334-3	2019	The Km values of free LPO and LPO immobilized on Fe3O4 were 53.19, 72.46 mM and their Vmax values were 0.629, 0.576 micromol/mL min respectively.	ferryl iron	49-54	lactoperoxidase	Homo sapiens	22-25
31612334-3	2019	The Km values of free LPO and LPO immobilized on Fe3O4 were 53.19, 72.46 mM and their Vmax values were 0.629, 0.576 micromol/mL min respectively.	ferryl iron	49-54	lactoperoxidase	Homo sapiens	30-33
31612334-5	2019	The LPO immobilized on Fe3O4 (LPO- Fe3O4) retained 28% of the initial activity within 30 days at 25  C whereas the free enzyme lost its activity after 7 days at the same temperature.	ferryl iron	23-28	lactoperoxidase	Homo sapiens	4-7
31612334-5	2019	The LPO immobilized on Fe3O4 (LPO- Fe3O4) retained 28% of the initial activity within 30 days at 25  C whereas the free enzyme lost its activity after 7 days at the same temperature.	ferryl iron	23-28	lactoperoxidase	Homo sapiens	30-33
31612334-5	2019	The LPO immobilized on Fe3O4 (LPO- Fe3O4) retained 28% of the initial activity within 30 days at 25  C whereas the free enzyme lost its activity after 7 days at the same temperature.	ferryl iron	35-40	lactoperoxidase	Homo sapiens	4-7
31612334-5	2019	The LPO immobilized on Fe3O4 (LPO- Fe3O4) retained 28% of the initial activity within 30 days at 25  C whereas the free enzyme lost its activity after 7 days at the same temperature.	ferryl iron	35-40	lactoperoxidase	Homo sapiens	30-33
31612334-6	2019	Moreover, evaluation of the thermal stability of LPO at 75  C determined the conservation of 19% of the initial activity of LPO in the LPO- Fe3O4 sample after 60 min whereas the free enzyme lost its activity after 5 min.	ferryl iron	140-145	lactoperoxidase	Homo sapiens	49-52
31612334-6	2019	Moreover, evaluation of the thermal stability of LPO at 75  C determined the conservation of 19% of the initial activity of LPO in the LPO- Fe3O4 sample after 60 min whereas the free enzyme lost its activity after 5 min.	ferryl iron	140-145	lactoperoxidase	Homo sapiens	124-127
31612334-6	2019	Moreover, evaluation of the thermal stability of LPO at 75  C determined the conservation of 19% of the initial activity of LPO in the LPO- Fe3O4 sample after 60 min whereas the free enzyme lost its activity after 5 min.	ferryl iron	140-145	lactoperoxidase	Homo sapiens	124-127
31336239-5	2019	BET surface area of Fe3O4@AC nps was found to be 129.6 m2/g by single point method and 1061.9 m2/g by multipoint method.	ferryl iron	20-25	delta/notch like EGF repeat containing	Homo sapiens	0-3
31546075-5	2019	The maximum adsorption amount of MC onto Fe3O4@MIL-68 (Al) was 248.05 mg g-1 (t = 160 min, pH = 6, Co = 60 mg L-1), and the adsorption kinetics followed a pseudo-second-order model, and the adsorption isotherms conformed to the Freundlich equation.	ferryl iron	41-46	immunoglobulin kappa variable 1-16	Homo sapiens	110-113
31499115-0	2019	A novel and biocompatible Fe3O4 loaded chitosan polyelectrolyte nanoparticles for the removal of Cd2+ ion.	ferryl iron	26-31	CD2 molecule	Homo sapiens	97-100
31499115-1	2019	In this work, Fe3O4 loaded chitosan (CS) nanoparticles (NPs) and microparticles (MPs) were synthesized based on ionic gelation technology for the removal of Cd2+ ion.	ferryl iron	14-19	CD2 molecule	Homo sapiens	157-160
31499115-3	2019	The results showed that particle size of Fe3O4 loaded CS NPs and MPs was in the range of 164.05-768.69 nm, and the former showed relatively higher adsorption capacities (97.86 mg/g) on Cd2+ ion than the latter after 90 min at pH 5.0 for the solutions with initial Cd2+ ion of 100 mg/L, respectively.	ferryl iron	41-46	CD2 molecule	Homo sapiens	185-188
31499115-3	2019	The results showed that particle size of Fe3O4 loaded CS NPs and MPs was in the range of 164.05-768.69 nm, and the former showed relatively higher adsorption capacities (97.86 mg/g) on Cd2+ ion than the latter after 90 min at pH 5.0 for the solutions with initial Cd2+ ion of 100 mg/L, respectively.	ferryl iron	41-46	CD2 molecule	Homo sapiens	264-267
31603456-0	2019	Glypican-3 (GPC3) targeted Fe3O4 core/Au shell nanocomplex for fluorescence/MRI/photoacoustic imaging-guided tumor photothermal therapy.	ferryl iron	27-32	glypican 3	Homo sapiens	0-10
31603456-0	2019	Glypican-3 (GPC3) targeted Fe3O4 core/Au shell nanocomplex for fluorescence/MRI/photoacoustic imaging-guided tumor photothermal therapy.	ferryl iron	27-32	glypican 3	Homo sapiens	12-16
31603456-2	2019	Herein, we successfully modified a previous phage display derived Glypican-3 (GPC3) binding peptide (GBP) on the surface of a Fe3O4 Core/Au shell nanocomplex (FANP) to improve GBP binding affinity and enhance FANP tumor photothermal therapy (PTT) efficacy.	ferryl iron	126-131	transmembrane protein 132A	Homo sapiens	101-104
31603456-2	2019	Herein, we successfully modified a previous phage display derived Glypican-3 (GPC3) binding peptide (GBP) on the surface of a Fe3O4 Core/Au shell nanocomplex (FANP) to improve GBP binding affinity and enhance FANP tumor photothermal therapy (PTT) efficacy.	ferryl iron	126-131	transmembrane protein 132A	Homo sapiens	176-179
31612334-7	2019	CONCLUSIONS: According to the present results, Fe3O4 magnetic nanoparticles are suitable for the immobilization of LPO.	ferryl iron	47-52	lactoperoxidase	Homo sapiens	115-118
31590050-6	2019	Meanwhile, the "nano-enzyme effect" of Fe3O4 NPs recovered the lipid-regulated proteins including PPARalpha, further triggering biodegradation pathways of TG, although the lipid-regulated proteins were obviously inhibited in the high-fat hepatocytes models.	ferryl iron	39-44	peroxisome proliferator activated receptor alpha	Homo sapiens	98-107
31781982-5	2019	The adsorption isotherm of Cd2+ on Fe3O4@PDA was in agreement with the Freundlich model, with the maximum adsorption capacity of 21.58 mg/g.	ferryl iron	35-40	CD2 molecule	Homo sapiens	27-30
31557580-4	2019	Electron microscopy, XPS and BET showed that the irregular Fe3O4 nanoparticles, sized between 20 and 40 nm, were disorderly dispersed on rGO sheets, which constituted a mesoporous material.	ferryl iron	59-64	delta/notch like EGF repeat containing	Homo sapiens	29-32
31775334-2	2019	Current research in this area is focused on the synthesis of poly(acrylamide) grafted Cell@Fe3O4 nanocomposites via oxidative free radical copolymerization of the acrylamide monomer and its application for the removal of Pb(II).	ferryl iron	91-96	submaxillary gland androgen regulated protein 3B	Homo sapiens	221-227
31687818-1	2019	Treatment of Fe[BF4]2 6H2O with 4,6-di(pyrazol-1-yl)-1H-pyrimid-2-one (HL1) or 4,6-di(4-methylpyrazol-1-yl)-1H-pyrimid-2-one (HL2) affords solvated crystals of [{FeIII(OH2)6}FeII8(mu-L)12][BF4]7 (1, HL = HL1; 2, HL = HL2).	ferryl iron	13-26	intelectin 1	Homo sapiens	71-74
31687818-1	2019	Treatment of Fe[BF4]2 6H2O with 4,6-di(pyrazol-1-yl)-1H-pyrimid-2-one (HL1) or 4,6-di(4-methylpyrazol-1-yl)-1H-pyrimid-2-one (HL2) affords solvated crystals of [{FeIII(OH2)6}FeII8(mu-L)12][BF4]7 (1, HL = HL1; 2, HL = HL2).	ferryl iron	13-26	intelectin 2	Homo sapiens	126-129
31687818-1	2019	Treatment of Fe[BF4]2 6H2O with 4,6-di(pyrazol-1-yl)-1H-pyrimid-2-one (HL1) or 4,6-di(4-methylpyrazol-1-yl)-1H-pyrimid-2-one (HL2) affords solvated crystals of [{FeIII(OH2)6}FeII8(mu-L)12][BF4]7 (1, HL = HL1; 2, HL = HL2).	ferryl iron	13-26	intelectin 1	Homo sapiens	204-207
31687818-1	2019	Treatment of Fe[BF4]2 6H2O with 4,6-di(pyrazol-1-yl)-1H-pyrimid-2-one (HL1) or 4,6-di(4-methylpyrazol-1-yl)-1H-pyrimid-2-one (HL2) affords solvated crystals of [{FeIII(OH2)6}FeII8(mu-L)12][BF4]7 (1, HL = HL1; 2, HL = HL2).	ferryl iron	13-26	intelectin 2	Homo sapiens	217-220
31775290-0	2019	Synthesis of MBA-Encoded Silver/Silica Core-Shell Nanoparticles as Novel SERS Tags for Biosensing Gibberellin A3 Based on Au@Fe3O4 as Substrate.	ferryl iron	125-130	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	98-112
31758327-1	2019	A binary magnetic metal-organic framework (MOF)-functionalized material (magG@PDA@Ni-MOF@Fe-MOF) was prepared through grafting Ni-MOF and Fe-MOF on magnetic (Fe3O4) graphene with polydopamine (PDA) as a middle layer.	ferryl iron	158-163	lysine acetyltransferase 8	Homo sapiens	18-48
31775290-9	2019	Based on antigen-antibody reaction, the immuno-Au@Fe3O4 nanoparticles can capture the GA3 and AgNPs@SiO2 SERS tags.	ferryl iron	50-55	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	86-89
31775334-0	2019	In Situ Copolymerized Polyacrylamide Cellulose Supported Fe3O4 Magnetic Nanocomposites for Adsorptive Removal of Pb(II): Artificial Neural Network Modeling and Experimental Studies.	ferryl iron	57-62	submaxillary gland androgen regulated protein 3B	Homo sapiens	113-119
33405674-4	2019	To achieve this aim, in our study, for the first time, we doped Fe3O4/graphene oxide (GO) nanocomposites into alpha-tricalcium phosphate (alpha-TCP)/calcium sulfate (CS) biphasic bone cement to prepare an injectable magnetic bone cement (alpha-TCP/CS/Fe3O4/GO, alphaCFG), which can be applied in bone tumor minimally invasive surgery and fit ideally even if the area is irregular.	ferryl iron	64-69	citrate synthase	Homo sapiens	166-168
31377520-1	2019	Present study described a magnetic adsorption and removal method with prepared magnetic core-shell Fe3O4@polyaniline microspheres for the removal of two typical BFRs, tetrabromobisphenol-A (TBBPA) and decabromodiphenyl ether (BDE-209) from water samples.	ferryl iron	99-104	homeobox D13	Homo sapiens	226-229
31377520-4	2019	The Magnetic core-shell Fe3O4@polyaniline exhibited excellent adsorption capability and removal rate to TBBPA and BDE 209.	ferryl iron	24-29	homeobox D13	Homo sapiens	114-117
31621307-5	2019	After four regeneration cycles, the Al(OH)3@Fe3O4 nanomaterials retain their magnetic property while still being able to remove ~40% silica from solutions at an adsorbent concentration of 2 g L-1.	ferryl iron	44-49	immunoglobulin kappa variable 1-16	Homo sapiens	192-195
31744202-3	2019	Here, polyethyleneimine (PEI)-modified magnetic Fe3O4 nanoparticles were prepared for the delivery of therapeutic siRNAs targeting B-cell lymphoma-2 (BCL2) and Baculoviral IAP repeat-containing 5 (BIRC5) into Ca9-22 oral cancer cells.	ferryl iron	48-53	BCL2 apoptosis regulator	Homo sapiens	131-148
31744202-3	2019	Here, polyethyleneimine (PEI)-modified magnetic Fe3O4 nanoparticles were prepared for the delivery of therapeutic siRNAs targeting B-cell lymphoma-2 (BCL2) and Baculoviral IAP repeat-containing 5 (BIRC5) into Ca9-22 oral cancer cells.	ferryl iron	48-53	BCL2 apoptosis regulator	Homo sapiens	150-154
31744202-3	2019	Here, polyethyleneimine (PEI)-modified magnetic Fe3O4 nanoparticles were prepared for the delivery of therapeutic siRNAs targeting B-cell lymphoma-2 (BCL2) and Baculoviral IAP repeat-containing 5 (BIRC5) into Ca9-22 oral cancer cells.	ferryl iron	48-53	baculoviral IAP repeat containing 5	Homo sapiens	160-195
31744202-3	2019	Here, polyethyleneimine (PEI)-modified magnetic Fe3O4 nanoparticles were prepared for the delivery of therapeutic siRNAs targeting B-cell lymphoma-2 (BCL2) and Baculoviral IAP repeat-containing 5 (BIRC5) into Ca9-22 oral cancer cells.	ferryl iron	48-53	baculoviral IAP repeat containing 5	Homo sapiens	197-202
31788599-0	2019	Mesoporous Layered Graphene Oxide/Fe3O4/C3N3S3 Polymer Hybrids for Rapid Removal of Pb2+ and Cd2+ from Water.	ferryl iron	34-39	CD2 molecule	Homo sapiens	93-96
33405527-0	2019	Reverse Microemulsion Synthesis of Fe3O4-Ag2S Heteronanocrystals for Dual-Modal Imaging-Guided Photothermal Tumor Ablation.	ferryl iron	35-40	angiotensin II receptor type 1	Homo sapiens	41-45
33405527-2	2019	Herein, we successfully synthesized heterogenous Fe3O4-Ag2S nanocrystals through a reverse microemulsion.	ferryl iron	49-54	angiotensin II receptor type 1	Homo sapiens	55-59
33405527-7	2019	Our work suggests that the potential of Fe3O4-Ag2S heteronanocrystals may be a promising theranostic agent for multimodal imaging guidance and photothermal therapy toward cancer.	ferryl iron	40-45	angiotensin II receptor type 1	Homo sapiens	46-50
33405674-4	2019	To achieve this aim, in our study, for the first time, we doped Fe3O4/graphene oxide (GO) nanocomposites into alpha-tricalcium phosphate (alpha-TCP)/calcium sulfate (CS) biphasic bone cement to prepare an injectable magnetic bone cement (alpha-TCP/CS/Fe3O4/GO, alphaCFG), which can be applied in bone tumor minimally invasive surgery and fit ideally even if the area is irregular.	ferryl iron	64-69	citrate synthase	Homo sapiens	248-250
31301797-2	2019	The M-PCTP combined both the properties of the PCTP and the magnetism of Fe3O4 nanoparticles, possessing highly porous structure and good magnetism.	ferryl iron	73-78	phosphatidylcholine transfer protein	Homo sapiens	6-10
31763571-4	2019	Transmission electron microscopy, Fourier transform infrared spectroscopy, Thermogravimetric analysis, XRD, and anti-CD34 immunofluorescence suggested that anti-CD34 and citric acid were successfully modified onto Fe3O4, and Prussian blue staining demonstrated the selectivity of the as-prepared nanoparticles for EPCs.	ferryl iron	214-219	CD34 molecule	Homo sapiens	117-121
31763571-4	2019	Transmission electron microscopy, Fourier transform infrared spectroscopy, Thermogravimetric analysis, XRD, and anti-CD34 immunofluorescence suggested that anti-CD34 and citric acid were successfully modified onto Fe3O4, and Prussian blue staining demonstrated the selectivity of the as-prepared nanoparticles for EPCs.	ferryl iron	214-219	CD34 molecule	Homo sapiens	161-165
31491561-2	2019	Here, polyacrylic acid (PAA)-coated Fe3O4 nanoparticles (PION) were synthesized and lethal reactions appeared when it was applied in vivo.	ferryl iron	36-41	gamma-secretase activating protein	Canis lupus familiaris	57-61
31576881-2	2019	PEG, PAMAM (G5) and matrix metalloproteinase 2 (MMP2) were attached to the surface of carboxylated Fe3O4 nanoparticles (NPs) using a chemical coupling method and then finally loaded with the photosensitizer chlorin e6 (Ce6).	ferryl iron	99-104	matrix metallopeptidase 2	Homo sapiens	20-46
31576881-2	2019	PEG, PAMAM (G5) and matrix metalloproteinase 2 (MMP2) were attached to the surface of carboxylated Fe3O4 nanoparticles (NPs) using a chemical coupling method and then finally loaded with the photosensitizer chlorin e6 (Ce6).	ferryl iron	99-104	matrix metallopeptidase 2	Homo sapiens	48-52
31359186-0	2019	Immobilization of tyrosinase on Fe3o4@Au core-shell nanoparticles as bio-probe for detection of dopamine, phenol and catechol.	ferryl iron	32-37	tyrosinase	Homo sapiens	18-28
31359186-1	2019	An optical bio-probe based on the immobilized tyrosinase on the surface of Fe3O4@Au was described for the detection of dopamine, phenol and catechol.	ferryl iron	75-80	tyrosinase	Homo sapiens	46-56
31359186-2	2019	The prepared bio-probe (Fe3O4@Au@tyrosinase) was characterized by means such as TEM, SEM, VSM, DLS and TGA.	ferryl iron	24-29	tyrosinase	Homo sapiens	33-43
31359186-2	2019	The prepared bio-probe (Fe3O4@Au@tyrosinase) was characterized by means such as TEM, SEM, VSM, DLS and TGA.	ferryl iron	24-29	T-box transcription factor 1	Homo sapiens	103-106
31359186-6	2019	The 0.003 mg/mL of tyrosinase was loaded on 1.65 mg/mL of the Fe3O4@Au.	ferryl iron	62-67	tyrosinase	Homo sapiens	19-29
31450094-0	2019	Novel electrochemical immunosensor for sensitive monitoring of cardiac troponin I using antigen-response cargo released from mesoporous Fe3O4.	ferryl iron	136-141	troponin I3, cardiac type	Homo sapiens	63-81
31450094-1	2019	A novel controlled release system-based antigen-response electrochemical immunosensor was developed for detecting cardiac troponin I (cTnI) by using aminated polystyrene microsphere (APSM) as molecular gate and Fe3O4 as nanocontainer.	ferryl iron	211-216	troponin I3, cardiac type	Homo sapiens	114-132
31450094-1	2019	A novel controlled release system-based antigen-response electrochemical immunosensor was developed for detecting cardiac troponin I (cTnI) by using aminated polystyrene microsphere (APSM) as molecular gate and Fe3O4 as nanocontainer.	ferryl iron	211-216	troponin I3, cardiac type	Homo sapiens	134-138
31420727-0	2019	Correction to: Immobilization of tyrosinase on Fe3o4@Au core-shell nanoparticles as bio-probe for detection of dopamine, phenol and catechol.	ferryl iron	47-52	tyrosinase	Homo sapiens	33-43
31222649-9	2019	PDA/Fe3O4/BC can treat actual electroplating wastewater with Cr(VI) concentration from 20 mg L-1 to less than 0.2 mg L-1, which met the PRC discharge standard (GB/21900-2008) of electroplating pollutants.	ferryl iron	4-9	immunoglobulin kappa variable 1-16	Homo sapiens	93-96
31125881-4	2019	Among them, VFM made from Fe3O4 NPs has the highest adsorption capacity (qt) with the adsorption amount of Cd2+ ions reaching about 29.3 mg/g within only 2 min due to the high specific surface area of NPs.	ferryl iron	26-31	CD2 molecule	Homo sapiens	107-110
31125881-6	2019	It was calculated that the equilibrium rate constant of VFM made from Fe3O4 NPs has reached about 0.28 g mg-1 min-1, much smaller than those of other membranes, which indicated a high Cd2+ ions removal efficiency.	ferryl iron	70-75	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	105-115
31125881-6	2019	It was calculated that the equilibrium rate constant of VFM made from Fe3O4 NPs has reached about 0.28 g mg-1 min-1, much smaller than those of other membranes, which indicated a high Cd2+ ions removal efficiency.	ferryl iron	70-75	CD2 molecule	Homo sapiens	184-187
31397998-7	2019	Subsequently, the iron ions released from the ionization of Fe3O4 in the acidic environment selectively convert H2O2 into highly toxic  OH by Fenton reaction, dramatically improving CDT with minimal systemic toxicity due to low NQO1 expression in normal tissues.	ferryl iron	60-65	NAD(P)H quinone dehydrogenase 1	Homo sapiens	228-232
31276379-3	2019	In 2007, we reported the first evidence that Fe3O4 nanoparticles (NPs) have intrinsic peroxidase-mimicking activity, and since that time, hundreds of nanomaterials have been found to mimic the catalytic activity of peroxidase, oxidase, catalase, haloperoxidase, glutathione peroxidase, uricase, methane monooxygenase, hydrolase, and superoxide dismutase.	ferryl iron	45-50	catalase	Homo sapiens	236-244
31276379-3	2019	In 2007, we reported the first evidence that Fe3O4 nanoparticles (NPs) have intrinsic peroxidase-mimicking activity, and since that time, hundreds of nanomaterials have been found to mimic the catalytic activity of peroxidase, oxidase, catalase, haloperoxidase, glutathione peroxidase, uricase, methane monooxygenase, hydrolase, and superoxide dismutase.	ferryl iron	45-50	urate oxidase (pseudogene)	Homo sapiens	286-293
31276379-5	2019	For example, Fe3O4 NPs show pH-dependent peroxidase-like and catalase-like activities; Prussian blue NPs simultaneously possess peroxidase-, catalase-, and superoxide dismutase-like activity; and Mn3O4 NPs mimic all three cellular antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase.	ferryl iron	13-18	catalase	Homo sapiens	61-69
31276379-5	2019	For example, Fe3O4 NPs show pH-dependent peroxidase-like and catalase-like activities; Prussian blue NPs simultaneously possess peroxidase-, catalase-, and superoxide dismutase-like activity; and Mn3O4 NPs mimic all three cellular antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase.	ferryl iron	13-18	catalase	Homo sapiens	141-149
31276379-5	2019	For example, Fe3O4 NPs show pH-dependent peroxidase-like and catalase-like activities; Prussian blue NPs simultaneously possess peroxidase-, catalase-, and superoxide dismutase-like activity; and Mn3O4 NPs mimic all three cellular antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase.	ferryl iron	13-18	catalase	Homo sapiens	141-149
31150674-2	2019	In this work, iron oxide nanoparticles-decorated carboxylated graphene oxide nanosheets (Fe3O4/cGO nanohybrid) were synthesized and incorporated in polyethersulfone (PES) hollow fiber ultrafiltration membranes (HFMs) and the resulting modified membranes were evaluated for the separation of proteins, namely lysozyme, trypsin, pepsin, human serum albumin, gamma-globulin and fibrinogen.	ferryl iron	89-94	fibrinogen beta chain	Homo sapiens	341-385
31150674-5	2019	PES-Fe3O4/cGO composite HFMs showed significantly high rejection of lysozyme (92.9 +- 1.3%), trypsin (94.5 +- 1.1%), pepsin (96.9 +- 1.2%), human serum albumin (99.5 +- 0.5%), human gamma-globulin (100%), and human fibrinogen (100%).	ferryl iron	4-9	fibrinogen beta chain	Homo sapiens	215-225
31128393-2	2019	This study deals with the removal of NO3- and HCO3- from contaminated wastewater using Fe-exchanged nano-bentonite and Fe3O4 nanoparticles.	ferryl iron	119-124	NBL1, DAN family BMP antagonist	Homo sapiens	37-40
30820758-0	2019	Development of Voltammetric Glucose-6-phosphate Biosensors Based on the Immobilization of Glucose-6-phosphate Dehydrogenase on Polypyrrole- and Chitosan-Coated Fe3O4 Nanoparticles/Polypyrrole Nanocomposite Films.	ferryl iron	160-165	glucose-6-phosphate dehydrogenase	Homo sapiens	90-123
31222649-9	2019	PDA/Fe3O4/BC can treat actual electroplating wastewater with Cr(VI) concentration from 20 mg L-1 to less than 0.2 mg L-1, which met the PRC discharge standard (GB/21900-2008) of electroplating pollutants.	ferryl iron	4-9	immunoglobulin kappa variable 1-16	Homo sapiens	117-120
31284012-1	2019	The performance of Fe3O4/attapulgite (APT) nanoparticles in Pb(II) adsorption from aqueous solutions could be improved by modifying the particles with aminopropyltriethoxysilane (APTS) and then combining with chitosan (CS) into beads.	ferryl iron	19-24	submaxillary gland androgen regulated protein 3B	Homo sapiens	60-66
31284012-8	2019	The results show that APTS-Fe3O4/APT@CS is a promising hybrid adsorbent for effective removal of Pb(II) from water.	ferryl iron	27-32	submaxillary gland androgen regulated protein 3B	Homo sapiens	97-103
31407583-5	2019	The hollow cavity can improve mass transfer; superparamagnetic Fe3O4 NPs embedded in the inner MOF shell can enhance the separation and recyclability; Pd NPs are highly dispersed in the matrix of the inner MOF shell, and the outer MOF shell acts as a protector to prevent the leaching of Pd NPs and a sieve to achieve size selectivity.	ferryl iron	63-68	lysine acetyltransferase 8	Homo sapiens	95-98
31150984-5	2019	Subsequently, Fe3O4 NPs anchored on the probes were transformed into a photothermal agent, Prussian blue NPs, which converted biological signal into heat via the near-infrared laser irradiation, and thus sensitive quantitative detection of PSA was realized by using a thermometer with a lower detection limit of 0.31 ng/mL.	ferryl iron	14-19	kallikrein related peptidase 3	Homo sapiens	240-243
31573547-8	2019	According to the caspase assay, Fe3O4/Ag nanocomposite enhances caspase 3 level.	ferryl iron	32-37	caspase 3	Homo sapiens	64-73
31085443-4	2019	Upon treatment by Fe3O4@MoS2, over 99% of 15 ppm Hg2+ can be removed in 2 min from aqueous solutions, with an initial adsorption rate as high as 52.62 g mg-1 min-1.	ferryl iron	18-23	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	153-163
31194193-2	2019	The Fe3O4@SiO2@Ti-MOF-NCs were characterized by various techniques, including FESEM, EDX, FTIR, BET, XRD and VSM.	ferryl iron	4-9	delta/notch like EGF repeat containing	Homo sapiens	96-99
31029342-2	2019	The structural features of Fe3O4@CaAl-LDH@l-Dopa were characterized using XRD, SEM, TEM, EDX, FT-IR, VSM, TGA, XPS, zeta potential analysis and BET.	ferryl iron	27-32	T-box transcription factor 1	Homo sapiens	106-109
31326033-3	2019	In the present study, the in vitro cellular uptake, antiproliferative activity, cytotoxicity, genotoxicity, prooxidant, microtubule-disrupting and apoptosis-inducing effect of Fe3O4@SiO2 and passivated Fe3O4@SiO2-NH2 nanoparticles on human renal proximal tubule epithelial cells (HK-2) have been studied.	ferryl iron	176-181	hexokinase 2	Homo sapiens	280-284
31326033-9	2019	Compared with vehicle control cells, a significantly higher amount of gammaH2AX foci correlating with an increase in DNA double-strand breaks was observed in Fe3O4@SiO2 and Fe3O4@SiO2-NH2-treated and immunestained HK-2 cells.	ferryl iron	158-163	hexokinase 2	Homo sapiens	214-218
31326033-9	2019	Compared with vehicle control cells, a significantly higher amount of gammaH2AX foci correlating with an increase in DNA double-strand breaks was observed in Fe3O4@SiO2 and Fe3O4@SiO2-NH2-treated and immunestained HK-2 cells.	ferryl iron	173-178	hexokinase 2	Homo sapiens	214-218
31317336-7	2019	The PAN and PAN/Fe3O4 fibers have a high adsorption capacity toward OB and Trf.	ferryl iron	16-21	transferrin	Homo sapiens	75-78
30943422-5	2019	Moreover, sensitive magnetic responsiveness (24.6 emu/g) of AL-DA/Fe3O4 NPs can be more helpful in recycling (over 90% recycled within 2 min) and multiple reusing.	ferryl iron	66-71	aldolase, fructose-bisphosphate A	Homo sapiens	60-65
31308407-10	2019	The kinetics investigations revealed 2.55 and 4.04 times increased rate of reactions compared to pristine Fe3O4 and CeO2, showing highest rate constant value of 18.2 x 10-3 min-1 for the ternary nanocomposite.	ferryl iron	106-111	CD59 molecule (CD59 blood group)	Homo sapiens	173-178
31252482-5	2019	In this study, a novel curative strategy which combines glucose oxidase (GOx)-mediated Fe3O4-based Fenton reaction and multiwalled carbon nanotube (MWNT)-produced mild hyperthermia enhancer is proposed, achieving a mild hyperthermia-enhanced enzyme-mediated tumor cell CDT.	ferryl iron	87-92	hydroxyacid oxidase 1	Homo sapiens	56-71
31252482-5	2019	In this study, a novel curative strategy which combines glucose oxidase (GOx)-mediated Fe3O4-based Fenton reaction and multiwalled carbon nanotube (MWNT)-produced mild hyperthermia enhancer is proposed, achieving a mild hyperthermia-enhanced enzyme-mediated tumor cell CDT.	ferryl iron	87-92	hydroxyacid oxidase 1	Homo sapiens	73-76
31252482-6	2019	GOx can catalyze the conversion of glucose into gluconic acid and H2O2, which can elevate acidity in the tumor microenvironment and boost Fe3O4-based Fenton reaction, producing a myriad of  OH to induce tumor cell death.	ferryl iron	138-143	hydroxyacid oxidase 1	Homo sapiens	0-3
31102228-2	2019	Then, Fe3O4@PVBC-TAEA nanoparticles were utilized as a novel adsorbent for removal of Pb(II) from aqueous media and optimal adsorption conditions were determined with response surface methodology (RSM).	ferryl iron	6-11	submaxillary gland androgen regulated protein 3B	Homo sapiens	86-92
30951773-2	2019	For this aim, anticancer 5-fluorouracil (5-FU) drug was loaded into chitosan/polyacrylic acid/Fe3O4 magnetic nanocomposite hydrogel (CS/PAA/Fe3O4) through immersing in the drug solution.	ferryl iron	94-99	citrate synthase	Homo sapiens	133-135
30951773-3	2019	The prepared CS/PAA/Fe3O4 was characterized using FT-IR, XRD, VSM, TGA and SEM analysis.	ferryl iron	20-25	citrate synthase	Homo sapiens	13-15
30951773-5	2019	The drug release tests showed that the CS/PAA/Fe3O4 enhanced the stability of drug dosing for a long time with controlled releases in the colon and rectal conditions.	ferryl iron	46-51	citrate synthase	Homo sapiens	39-41
30764944-0	2019	Organic/Inorganic Fe3O4@MCM-41@Zr-Piperazine: An Impressive Magnetite Nanocatalyst for N-Tert-Butoxycarbonylation of Amines.	ferryl iron	18-23	telomerase reverse transcriptase	Homo sapiens	89-93
30764944-1	2019	Fe3O4@MCM-41@Zirconium magnetic nanoparticles modified with piperazine (Fe3O4@MCM-41@Zr-piperazine), as a newly reported catalyst, shows excellent catalytic activity in N-Tert-butoxycarbonylation of amines under the mild and solvent-free conditions.	ferryl iron	0-5	telomerase reverse transcriptase	Homo sapiens	171-175
30764944-1	2019	Fe3O4@MCM-41@Zirconium magnetic nanoparticles modified with piperazine (Fe3O4@MCM-41@Zr-piperazine), as a newly reported catalyst, shows excellent catalytic activity in N-Tert-butoxycarbonylation of amines under the mild and solvent-free conditions.	ferryl iron	72-77	telomerase reverse transcriptase	Homo sapiens	171-175
30913488-2	2019	The effect of different Fe3O4 contents on composites" properties was detected through XRD, SEM, TEM, HR-TEM, XPS, Uv-vis DRS, PL and BET.	ferryl iron	24-29	delta/notch like EGF repeat containing	Homo sapiens	133-136
31070196-11	2019	The Fe3O4@PDA NPs enhanced stromal cell-derived factor-1/CXCR4-mediated MSC migration in vivo.	ferryl iron	4-9	C-X-C motif chemokine ligand 12	Rattus norvegicus	27-56
31070196-11	2019	The Fe3O4@PDA NPs enhanced stromal cell-derived factor-1/CXCR4-mediated MSC migration in vivo.	ferryl iron	4-9	C-X-C motif chemokine receptor 4	Rattus norvegicus	57-62
30879683-3	2019	With a theoretical production rate of 2.35 kg h-1, the as-prepared CMC-Fe3O4 exhibited better adsorption capacity and faster rate for Pb(II) than those of pure Fe3O4, and the maximum adsorption capacity of Pb(II) reached up to 152.0 mg g-1.	ferryl iron	71-76	submaxillary gland androgen regulated protein 3B	Homo sapiens	134-140
30879683-3	2019	With a theoretical production rate of 2.35 kg h-1, the as-prepared CMC-Fe3O4 exhibited better adsorption capacity and faster rate for Pb(II) than those of pure Fe3O4, and the maximum adsorption capacity of Pb(II) reached up to 152.0 mg g-1.	ferryl iron	71-76	submaxillary gland androgen regulated protein 3B	Homo sapiens	206-212
30101367-0	2019	Chloro-Modified Magnetic Fe3O4@MCM-41 Core-Shell Nanoparticles for L-Asparaginase Immobilization with Improved Catalytic Activity, Reusability, and Storage Stability.	ferryl iron	25-30	asparaginase and isoaspartyl peptidase 1	Homo sapiens	67-81
31020528-2	2019	Magnetic Fe3O4-coated hydroxyapatite (HAP) nanoparticles (nHAP-Fe3O4) were developed by co-precipitation and then used for the removal of Cd2+ from water.	ferryl iron	9-14	CD2 molecule	Homo sapiens	138-141
31020528-7	2019	The mechanisms for the adsorption of Cd2+ on nHAP-Fe3O4 included rapid surface adsorption, intraparticle diffusion, and internal particle bonding, with the ion exchange with Ca2+ and chemical complexation being the most dominant.	ferryl iron	50-55	CD2 molecule	Homo sapiens	37-40
30832917-6	2019	Furthermore, PSA capture antibodies functionalized magnetic Fe3O4 nanoparticles (Fe3O4-Ab1) were utilized in the proposed immunosensor to capture and enrich the PSA.	ferryl iron	60-65	kallikrein related peptidase 3	Homo sapiens	13-16
30832917-6	2019	Furthermore, PSA capture antibodies functionalized magnetic Fe3O4 nanoparticles (Fe3O4-Ab1) were utilized in the proposed immunosensor to capture and enrich the PSA.	ferryl iron	60-65	kallikrein related peptidase 3	Homo sapiens	161-164
31151258-2	2019	Herein, we report on the synthesis of PANI composites with magnetic oxide (Fe3O4) for efficient removal of Basic Blue 3 (BB3) dye from aqueous solution.	ferryl iron	75-80	bombesin receptor subtype 3	Homo sapiens	107-124
30735779-1	2019	This work is directed towards the synthesis of the magnetic nanoparticle in a core and a gold shell with immobilized of laccase on its surface (Fe3O4@Au@ Lac).	ferryl iron	144-149	lactase	Homo sapiens	154-157
30735779-2	2019	The prepared Fe3O4@Au@ Lac core/shell nanoparticles are characterized by means TEM, SEM, DLS, zeta potential, UV-Vis, and TGA.	ferryl iron	13-18	lactase	Homo sapiens	23-26
30735779-2	2019	The prepared Fe3O4@Au@ Lac core/shell nanoparticles are characterized by means TEM, SEM, DLS, zeta potential, UV-Vis, and TGA.	ferryl iron	13-18	T-box transcription factor 1	Homo sapiens	122-125
30711758-5	2019	The analyte cTnI collected via Fe3O4@PDA-dAb immune probe can be specially recognized by cAb immobilized on the sensing platform.	ferryl iron	31-36	troponin I3, cardiac type	Homo sapiens	12-16
30898670-7	2019	A significant decrease in NO production was induced which coincided with the inhibition of endothelial nitric oxide synthase (eNOS) activity in serum and endothelium of plaque in ApoE-/- mice injected with low-dose Fe3O4-AG NPs in vivo and HUVECs treated with low-dose Fe3O4-AG NPs in vitro.	ferryl iron	215-220	nitric oxide synthase 3, endothelial cell	Mus musculus	91-124
30898670-7	2019	A significant decrease in NO production was induced which coincided with the inhibition of endothelial nitric oxide synthase (eNOS) activity in serum and endothelium of plaque in ApoE-/- mice injected with low-dose Fe3O4-AG NPs in vivo and HUVECs treated with low-dose Fe3O4-AG NPs in vitro.	ferryl iron	215-220	apolipoprotein E	Mus musculus	179-183
30712592-2	2019	Herein, a facile strategy was introduced to synthesize the magnetic gamma-cyclodextrin polymer (Fe3O4@PDA@gamma-CDP) composite and set it as a novel adsorbent with excellent properties for the magnetic solid-phase extraction (MSPE) of MCs.	ferryl iron	96-101	cut like homeobox 1	Homo sapiens	112-115
30712592-3	2019	The prepared Fe3O4@PDA@gamma-CDP microspheres exhibit good aqueous dispersibility and highly affinity for MCs, thus contribute to an excellent extraction performance for trace MCs in water samples.	ferryl iron	13-18	cut like homeobox 1	Homo sapiens	29-32
30977474-4	2019	Herein, we have described a composite material that could encapsulate a magnetic Fe3O4 core in a MIL-100 shell (MMs), which could respond to pH changes and modify the anti-EpCAM antibody (anti-EpCAM-MMs) on the surface of MIL-100.	ferryl iron	81-86	epithelial cell adhesion molecule	Homo sapiens	172-177
30977474-4	2019	Herein, we have described a composite material that could encapsulate a magnetic Fe3O4 core in a MIL-100 shell (MMs), which could respond to pH changes and modify the anti-EpCAM antibody (anti-EpCAM-MMs) on the surface of MIL-100.	ferryl iron	81-86	epithelial cell adhesion molecule	Homo sapiens	193-198
31163762-2	2019	Stable mode-locked operation can be conveniently achieved based on the interaction between Ex-TFG coupled light and deposited ferroferric-oxide (Fe3O4) nanoparticles.	ferryl iron	145-150	trafficking from ER to golgi regulator	Homo sapiens	94-97
31163762-5	2019	For the first time, to the best of our knowledge, Ex-TFG based Fe3O4 SA for mode-locked fiber laser is demonstrated.	ferryl iron	63-68	trafficking from ER to golgi regulator	Homo sapiens	53-56
30550968-3	2019	Herein, we fabricated the carbon dots/fatty acid-coated MNPs (CDs/C11-Fe3O4) through a facile and simple method.	ferryl iron	70-75	aldo-keto reductase family 1 member C4	Homo sapiens	66-69
30550968-7	2019	The adsorption processes of BaP on both C11-Fe3O4 and CDs/C11-Fe3O4 nanocomposites are exothermic, and well simulated by pseudo-second-order model.	ferryl iron	44-49	prohibitin 2	Homo sapiens	28-31
30550968-7	2019	The adsorption processes of BaP on both C11-Fe3O4 and CDs/C11-Fe3O4 nanocomposites are exothermic, and well simulated by pseudo-second-order model.	ferryl iron	44-49	aldo-keto reductase family 1 member C4	Homo sapiens	40-43
30550968-7	2019	The adsorption processes of BaP on both C11-Fe3O4 and CDs/C11-Fe3O4 nanocomposites are exothermic, and well simulated by pseudo-second-order model.	ferryl iron	62-67	prohibitin 2	Homo sapiens	28-31
30550968-7	2019	The adsorption processes of BaP on both C11-Fe3O4 and CDs/C11-Fe3O4 nanocomposites are exothermic, and well simulated by pseudo-second-order model.	ferryl iron	62-67	aldo-keto reductase family 1 member C4	Homo sapiens	58-61
30855038-2	2019	The CuO/ZnO@Fe3O4-CNTs-NC was characterized by FESEM, EDS, XRD, TEM, BET, FT-IR, and VSM.	ferryl iron	12-17	delta/notch like EGF repeat containing	Homo sapiens	69-72
31087928-1	2019	In order to improve the adsorption-separation of Cd2+ in water treatment, magnetic Fe3O4 coated Ca(H2PO4)2 nanoparticles (NMCDP) were developed by coprecipitation.	ferryl iron	83-88	CD2 molecule	Homo sapiens	49-52
32073578-3	2019	PDA is first deposited on the surfaces of iron oxide NPs through self-polymerization, and then GOx is covalently linked with PDA upon mixing the enzyme and Fe3O4@PDA under alkaline conditions.	ferryl iron	156-161	hydroxyacid oxidase 1, liver	Mus musculus	95-98
30821439-2	2019	Herein, a core-shell magnetic gold nanostar (Fe3O4@GNS, MGNS)-based system for codelivery of a mitochondrial targeting amphipathic tail-anchoring peptide (ATAP) and a membrane-associated cytokine (tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL) was constructed.	ferryl iron	45-50	TNF superfamily member 10	Homo sapiens	254-259
30745282-2	2019	In this study, we developed a DSN-assisted dual-SERS biosensor for microRNA-10b in exosome and residual plasma of blood samples detection based on the Fe3O4 @Ag-DNA-Au@Ag@DTNB (SERS tag) conjugates.	ferryl iron	151-156	microRNA 10b	Homo sapiens	67-79
30880516-3	2019	METHODS: We prepared Fe3O4 nanoparticles using a chemical co-precipitation method, performed coupling with chitosan to prepare LHRH-Fe3O4 nanoparticles, and explored the application value of LHRH-Fe3O4 nanoparticles in targeted imaging and treatment of breast tumors through in vitro and in vivo experiments.	ferryl iron	132-137	gonadotropin releasing hormone 1	Homo sapiens	127-131
30880516-3	2019	METHODS: We prepared Fe3O4 nanoparticles using a chemical co-precipitation method, performed coupling with chitosan to prepare LHRH-Fe3O4 nanoparticles, and explored the application value of LHRH-Fe3O4 nanoparticles in targeted imaging and treatment of breast tumors through in vitro and in vivo experiments.	ferryl iron	132-137	gonadotropin releasing hormone 1	Homo sapiens	127-131
30880516-4	2019	RESULTS: The particle size of the LHRH-Fe3O4 nanoparticles was 10 nm, and they could be taken in by human MCF-7 breast cancer cells.	ferryl iron	39-44	gonadotropin releasing hormone 1	Homo sapiens	34-38
30880516-6	2019	In vivo MRI experiments showed that LHRH-Fe3O4 could effectively concentrate on the tumor under the action of a magnetic field.	ferryl iron	41-46	gonadotropin releasing hormone 1	Homo sapiens	36-40
30880516-8	2019	CONCLUSION: LHRH-Fe3O4 nanoparticles serve the purpose of targeting contrast agents to target sites and are expected to be used for targeted imaging and treatment of cancers with high LHRH expression.	ferryl iron	17-22	gonadotropin releasing hormone 1	Homo sapiens	12-16
30880516-8	2019	CONCLUSION: LHRH-Fe3O4 nanoparticles serve the purpose of targeting contrast agents to target sites and are expected to be used for targeted imaging and treatment of cancers with high LHRH expression.	ferryl iron	17-22	gonadotropin releasing hormone 1	Homo sapiens	184-188
30678949-1	2019	Surface modification of Fe3O4 nanoparticle with thiol groups was used for the immobilization of silver nano-particles to produce Fe3O4/SiO2-Pr-S-Ag NPs.	ferryl iron	24-29	S-antigen visual arrestin	Homo sapiens	143-147
30678949-1	2019	Surface modification of Fe3O4 nanoparticle with thiol groups was used for the immobilization of silver nano-particles to produce Fe3O4/SiO2-Pr-S-Ag NPs.	ferryl iron	129-134	S-antigen visual arrestin	Homo sapiens	143-147
30678949-4	2019	Fe3O4/SiO2-Pr-S-Ag NPs show high catalytic activity as recyclable nanocatalyst toward degradation of 4-nitrophenol (4-NP), rhodamine B (RhB), and Methylene blue (MB) in the presence of NaBH4 in water at room temperature.	ferryl iron	0-5	S-antigen visual arrestin	Homo sapiens	14-18
31096419-1	2019	Magnetic Fe3O4-encapsulated C3N3S3 polymer/reduced graphene oxide composite (rGO-poly(C3N3S3)/Fe3O4) was synthesized to remove Pb(II) and Hg(II) from aqueous solutions.	ferryl iron	9-14	submaxillary gland androgen regulated protein 3B	Homo sapiens	127-144
31096419-1	2019	Magnetic Fe3O4-encapsulated C3N3S3 polymer/reduced graphene oxide composite (rGO-poly(C3N3S3)/Fe3O4) was synthesized to remove Pb(II) and Hg(II) from aqueous solutions.	ferryl iron	94-99	submaxillary gland androgen regulated protein 3B	Homo sapiens	127-144
30625519-2	2019	Core-shell structured Fe3O4@SiO2 nanoparticles were synthesized by chemical coprecipitation, followed by functionalization with amino groups and immobilization of pig IgG antibodies.	ferryl iron	22-27	IGG	Sus scrofa	167-170
30625522-8	2019	Additionally, using the Fe3O4 @PAMAM@alpha-Glu microspheres in the inhibition assay, the enzymatic reaction could be stopped by magnetic separation instead of the traditional addition of Na2CO3 solution, which not only eliminated the disturbance of termination reagent to the results, but also reused the immobilized alpha-glucosidase.	ferryl iron	24-29	sucrase-isomaltase	Homo sapiens	317-334
30904972-12	2019	Graphical abstract Schematic presentation of polyamidoamine (PAMAM) dendrimers modified magnetite (Fe3O4) nanoparticles as electrochemical sensing platform using redox dyes Prussian blue and toluidine blue for simultaneous detection of alpha-fetoprotein (AFP) and glypican-3 (GPC-3), respectively by differential pulse voltammetry.	ferryl iron	99-104	alpha fetoprotein	Homo sapiens	236-253
30904972-12	2019	Graphical abstract Schematic presentation of polyamidoamine (PAMAM) dendrimers modified magnetite (Fe3O4) nanoparticles as electrochemical sensing platform using redox dyes Prussian blue and toluidine blue for simultaneous detection of alpha-fetoprotein (AFP) and glypican-3 (GPC-3), respectively by differential pulse voltammetry.	ferryl iron	99-104	alpha fetoprotein	Homo sapiens	255-258
30904972-12	2019	Graphical abstract Schematic presentation of polyamidoamine (PAMAM) dendrimers modified magnetite (Fe3O4) nanoparticles as electrochemical sensing platform using redox dyes Prussian blue and toluidine blue for simultaneous detection of alpha-fetoprotein (AFP) and glypican-3 (GPC-3), respectively by differential pulse voltammetry.	ferryl iron	99-104	glypican 3	Homo sapiens	264-274
30904972-12	2019	Graphical abstract Schematic presentation of polyamidoamine (PAMAM) dendrimers modified magnetite (Fe3O4) nanoparticles as electrochemical sensing platform using redox dyes Prussian blue and toluidine blue for simultaneous detection of alpha-fetoprotein (AFP) and glypican-3 (GPC-3), respectively by differential pulse voltammetry.	ferryl iron	99-104	glypican 3	Homo sapiens	276-281
30862882-4	2019	In vitro heating experiments on microglial BV2 cells under an ac magnetic field (H0 = 23.87 kA/m; f = 571 kHz) yielded specific power absorption (SPA) values of SPA = 43 +- 3 and 49 +- 1 muW/cell for PEI-Fe3O4 and Au@PEI-Fe3O4 NPs, respectively.	ferryl iron	204-209	sperm head anomaly 3	Mus musculus	161-190
30101367-11	2019	In conclusion, the Fe3O4@MCM-41-Cl@L-ASNase core-shell nanoparticles could successfully be used in industrial and medical applications.	ferryl iron	19-24	asparaginase and isoaspartyl peptidase 1	Homo sapiens	35-43
30384050-0	2019	Adsorption behavior and mechanism of Mg/Fe layered double hydroxide with Fe3O4-carbon spheres on the removal of Pb(II) and Cu(II).	ferryl iron	73-78	submaxillary gland androgen regulated protein 3B	Homo sapiens	112-129
30735954-4	2019	Hence, in this study, we investigated the interaction of folic acid functionalized gold nanoparticles and gold-shelled Fe3O4 nanoparticles with microtubule and microtubule associated protein tau in order to introduce intracellular targets of these nanoparticles and provide a holistic view about the mechanism of action of gold nanoparticles used in photothermal therapy.	ferryl iron	119-124	microtubule associated protein tau	Homo sapiens	160-194
30606543-3	2019	The prepared support (IL-CS-Fe3O4), which was used to immobilize porcine pancreatic lipase (PPL), was characterized using Fourier transform infrared (FTIR) spectroscopy, vibrating sample magnetometry (VSM), thermogravimetry (TG), transmission electron microscopy (TEM) and X-ray diffraction (XRD).	ferryl iron	28-33	periplakin	Homo sapiens	92-95
30606543-5	2019	The immobilized PPL (PPL-IL-CS-Fe3O4) exhibited 1.93-fold higher specific activity than PPL-CS-Fe3O4 when triacetin was used as the substrate, and showed 95 mg/g of lipase immobilization capacity and 382% of activity recovery.	ferryl iron	31-36	periplakin	Homo sapiens	16-19
30606543-5	2019	The immobilized PPL (PPL-IL-CS-Fe3O4) exhibited 1.93-fold higher specific activity than PPL-CS-Fe3O4 when triacetin was used as the substrate, and showed 95 mg/g of lipase immobilization capacity and 382% of activity recovery.	ferryl iron	31-36	periplakin	Homo sapiens	21-24
30606543-6	2019	The residual activity of PPL-IL-CS-Fe3O4 was above 60% of the initial activity after incubation at 50  C for 6 h, as was higher than that of PPL-CS-Fe3O4 which showed 40% of the initial activity.	ferryl iron	35-40	periplakin	Homo sapiens	25-28
30606543-7	2019	In addition, PPL-IL-CS-Fe3O4 retained 84.6% of the initial activity after 10 cycles, whereas PPL-CS-Fe3O4 retained only 75.5% activity.	ferryl iron	23-28	periplakin	Homo sapiens	13-16
30688463-2	2019	Based on the catalytic activity and photothermal and magnetic responsiveness originating from catalase and Fe3O4 NPs, respectively, the resulting micromotor exhibits an autonomous movement in the presence of hydrogen peroxide (H2O2) fuel, controlled motion velocity under light irradiation, and guided movement direction upon the application of an external magnetic field.	ferryl iron	107-112	catalase	Homo sapiens	94-102
30384017-2	2019	Herein, a novel fluorometric assay based on the acetylcholinesterase (AChE) inhibited enzymatic activity and the new peroxidase-like Fe3O4 nanoparticles@ZIF-8 composite (Fe3O4 NPs@ZIF-8) was developed for the determination of OPs.	ferryl iron	133-138	acetylcholinesterase (Cartwright blood group)	Homo sapiens	70-74
30741341-0	2019	Voltammetric immunosensor for E-cadherin promoter DNA methylation using a Fe3O4-citric acid nanocomposite and a screen-printed carbon electrode modified with poly(vinyl alcohol) and reduced graphene oxide.	ferryl iron	74-79	cadherin 1	Homo sapiens	30-40
29728047-1	2019	In this study, poly[2-methacryloyloxyethyl phosphorylcholine (MPC)]-protected Fe3O4 nanoparticles were prepared and used for the label-free specific detection and collection of an acute inflammation marker, C-reactive protein (CRP), in a simulated body fluid.	ferryl iron	78-83	C-reactive protein	Homo sapiens	207-225
29728047-1	2019	In this study, poly[2-methacryloyloxyethyl phosphorylcholine (MPC)]-protected Fe3O4 nanoparticles were prepared and used for the label-free specific detection and collection of an acute inflammation marker, C-reactive protein (CRP), in a simulated body fluid.	ferryl iron	78-83	C-reactive protein	Homo sapiens	227-230
29728047-11	2019	CRP-containing aqueous solutions were treated with poly(MPC)-protected Fe3O4.	ferryl iron	71-76	C-reactive protein	Homo sapiens	0-3
29728047-12	2019	After poly(MPC)-protected Fe3O4 nanoparticles were separated using a neodymium magnet and centrifugation, the concentration of CRP in the media dramatically decreased.	ferryl iron	26-31	C-reactive protein	Homo sapiens	127-130
30787607-8	2019	Results: Cell targeting experiments and magnetic resonance (MR) signal and T2 measurements showed that the Fe3O4@DMSA@Ab nanoprobes have specific binding affinity for CD20-positive cells.	ferryl iron	107-112	keratin 20	Homo sapiens	167-171
30787607-12	2019	Conclusion: These results indicate that Fe3O4@DMSA@Ab nanoprobes have the potential to serve as MRI tracers and therapeutic agents for CD20-positive cells.	ferryl iron	40-45	keratin 20	Homo sapiens	135-139
30596557-3	2019	In this study, magnetic endoglin aptamer (mEND) imaging nanoprobes based on mEND-modified magnetic carboxymethyl chitosan (CMCS) nanoparticles (denoted mEND-Fe3O4@CMCS) were developed.	ferryl iron	157-162	endoglin	Mus musculus	24-32
30360203-5	2019	MgAC[0.7 g]-Fe3O4 nanocomposite exhibited the best photo-Fenton catalysis with methylene blue (MB) was completely removed from the treatment solution at a constant rate of 0.0083 (min-1) on the batch scale.	ferryl iron	12-17	CD59 molecule (CD59 blood group)	Homo sapiens	180-185
30586282-3	2019	Aptamer-modified Ag/CdO NPs were assembled on the surface of superparamagnetic Fe3O4/graphene oxide nanosheets (GO/Fe3O4 NSs) through the hydrophobic and pi-pi stacking interaction of aptamers and GO NSs.	ferryl iron	79-84	cell adhesion associated, oncogene regulated	Homo sapiens	20-23
30368277-3	2019	Compare with the physical mixture, in-situ insertion of MWCNTs in the Fe3O4/N/C formed Fe3O4/N/C@MWCNTs composite has the higher conductivity, larger BET surface area and more satisfying electrocatalytic properties.	ferryl iron	70-75	delta/notch like EGF repeat containing	Homo sapiens	150-153
30368277-3	2019	Compare with the physical mixture, in-situ insertion of MWCNTs in the Fe3O4/N/C formed Fe3O4/N/C@MWCNTs composite has the higher conductivity, larger BET surface area and more satisfying electrocatalytic properties.	ferryl iron	87-92	delta/notch like EGF repeat containing	Homo sapiens	150-153
30586282-3	2019	Aptamer-modified Ag/CdO NPs were assembled on the surface of superparamagnetic Fe3O4/graphene oxide nanosheets (GO/Fe3O4 NSs) through the hydrophobic and pi-pi stacking interaction of aptamers and GO NSs.	ferryl iron	115-120	cell adhesion associated, oncogene regulated	Homo sapiens	20-23
30475352-6	2019	The obtained BA-modified Fe3O4@SiO2 magnetic nanoparticles were applied in the attempted enrichment of two glycoproteins (ovalbumin (OVA) and transferrin (TRF)) and two non-glycoproteins (bovine serum albumin (BSA) and cytochrome c (Cyt C)).	ferryl iron	25-30	cytochrome c, somatic	Homo sapiens	219-231
30567652-1	2019	Herein, a novel magnetic biocomposite (Fe3O4@Au-S1/S2) was applied to analyze thrombin.	ferryl iron	39-44	coagulation factor II, thrombin	Homo sapiens	78-86
30567652-2	2019	The Fe3O4@Au-S1/S2 consisted of Fe3O4@Au nanoparticles (Fe3O4@Au NPs) as carriers for magnetic separation and magnetic field-induced self-assembly, thiolated complementary strand (S1) anchored based on Au-S bond and thrombin binding aptamer (S2) as a recognition element.	ferryl iron	4-9	coagulation factor II, thrombin	Homo sapiens	216-224
30475352-6	2019	The obtained BA-modified Fe3O4@SiO2 magnetic nanoparticles were applied in the attempted enrichment of two glycoproteins (ovalbumin (OVA) and transferrin (TRF)) and two non-glycoproteins (bovine serum albumin (BSA) and cytochrome c (Cyt C)).	ferryl iron	25-30	cytochrome c, somatic	Homo sapiens	233-238
30475352-8	2019	In addition, the recognition capability of the Fe3O4@SiO2-BA nanoparticles was demonstrated by the selective enrichment of glycoproteins from a complex system containing both glycoproteins (i.e., TRF) and non-glycoproteins (i.e., Cyt C).	ferryl iron	47-52	cytochrome c, somatic	Homo sapiens	230-235
30558201-5	2018	The AChE/Fe3O4@MHCS/GCE electrochemical sensor that was operated with an incubation time of 12 min at the malathion concentration ranges between 0.01-50 ppb and 50-600 ppb had a detection limit of 0.0182 ppb (S/N = 3).	ferryl iron	9-14	aminomethyltransferase	Homo sapiens	20-23
30384017-2	2019	Herein, a novel fluorometric assay based on the acetylcholinesterase (AChE) inhibited enzymatic activity and the new peroxidase-like Fe3O4 nanoparticles@ZIF-8 composite (Fe3O4 NPs@ZIF-8) was developed for the determination of OPs.	ferryl iron	170-175	acetylcholinesterase (Cartwright blood group)	Homo sapiens	70-74
29911263-0	2019	Novel Competitive Chemiluminescence DNA Assay Based on Fe3O4@SiO2@Au-Functionalized Magnetic Nanoparticles for Sensitive Detection of p53 Tumor Suppressor Gene.	ferryl iron	55-60	tumor protein p53	Homo sapiens	134-137
29911263-1	2019	A simple, rapid response time and ultrahigh sensitive chemiluminescence (CL) DNA assay based on Fe3O4@SiO2@Au-functionalized magnetic nanoparticles (Au-MNPs) was developed for detection of p53 tumor suppressor gene.	ferryl iron	96-101	tumor protein p53	Homo sapiens	189-192
30262098-3	2019	In this work, a novel immunoaffinity probe, Fe3O4@TpBD-DSS-Ab-MEG, based on magnetic COFs with ordered arrangement of anchored antibodies has been developed and applied for the first time to detection of a cancer biomarker, heat shock protein 90alpha (Hsp90alpha).	ferryl iron	44-49	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	62-65
30262098-3	2019	In this work, a novel immunoaffinity probe, Fe3O4@TpBD-DSS-Ab-MEG, based on magnetic COFs with ordered arrangement of anchored antibodies has been developed and applied for the first time to detection of a cancer biomarker, heat shock protein 90alpha (Hsp90alpha).	ferryl iron	44-49	heat shock protein 90 alpha family class A member 1	Homo sapiens	252-262
30262098-5	2019	Fe3O4@TpBD-DSS-Ab-MEG demonstrated low detection limit (50 pg/mL), high selectivity (Hsp90alpha:BSA = 1:1000), desirable repeatability and good stability for Hsp90alpha immunocapture.	ferryl iron	0-5	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	18-21
30262098-5	2019	Fe3O4@TpBD-DSS-Ab-MEG demonstrated low detection limit (50 pg/mL), high selectivity (Hsp90alpha:BSA = 1:1000), desirable repeatability and good stability for Hsp90alpha immunocapture.	ferryl iron	0-5	heat shock protein 90 alpha family class A member 1	Homo sapiens	85-95
30262098-5	2019	Fe3O4@TpBD-DSS-Ab-MEG demonstrated low detection limit (50 pg/mL), high selectivity (Hsp90alpha:BSA = 1:1000), desirable repeatability and good stability for Hsp90alpha immunocapture.	ferryl iron	0-5	heat shock protein 90 alpha family class A member 1	Homo sapiens	158-168
30223168-3	2018	However, at the higher concentration of nano-Fe3O4 dosage (2000 mg/L), there was a significant increase in biomass, antioxidant enzymes superoxide dismutase (SOD) and peroxidase (POD).	ferryl iron	45-50	peroxidase 2-like	Cucumis sativus	167-177
30223168-3	2018	However, at the higher concentration of nano-Fe3O4 dosage (2000 mg/L), there was a significant increase in biomass, antioxidant enzymes superoxide dismutase (SOD) and peroxidase (POD).	ferryl iron	45-50	peroxidase 2-like	Cucumis sativus	179-182
30558201-6	2018	Moreover, the AChE/MHCS/GCE and AChE/Fe3O4@MHCS/GCE biosensors were effective for the detection of real samples, and were demonstrated to be suitable for the field-testing of organophosphorus pesticide (OP) residues.	ferryl iron	37-42	aminomethyltransferase	Homo sapiens	48-51
30243119-0	2018	Study on the oxidation of fibrinogen using Fe3O4 magnetic nanoparticles and its influence to the formation of fibrin.	ferryl iron	43-48	fibrinogen beta chain	Homo sapiens	26-36
30243119-2	2018	In this work, H2O2 and H2O2-Fe3O4 magnetic nanoparticles were used as two reactive oxygen species to study the oxidative stress for the structure and polymerization behaviour of fibrinogen molecules.	ferryl iron	28-33	fibrinogen beta chain	Homo sapiens	178-188
30189924-5	2018	Subsequently, the magnetic nanoparticles Fe3O4 and TbBim(Asp)2 were encapsulated in chitosan microspheres to prepare magnetic fluorescent bifunctional drug delivery system Fe3O4/TbBim(Asp)2/Chitosan.	ferryl iron	172-177	beta-secretase 1	Homo sapiens	57-62
30274047-6	2018	Bovine serum albumin (BSA) was used as a blocking agent to block the non-specific sites onto Anti-VD/Fe3O4-PANnFs/ITO electrode surface.	ferryl iron	101-106	albumin	Homo sapiens	7-20
30460410-3	2018	The Fe3O4/KAP composite was obtained by coprecipitation of KAP with magnetite nanoparticles.	ferryl iron	4-9	napsin A aspartic peptidase	Homo sapiens	59-62
30172815-6	2018	DNA fragmentation and caspase-3 activity were higher in MCF-7 cells treated with MTX/CS-Fe3O4-NPs than that of MTX.	ferryl iron	88-93	caspase 3	Homo sapiens	22-31
30274135-4	2018	In this study, Cy5.5-labeled, NGR-conjugated iron oxide nanoparticles (Cy5.5-NGR-Fe3O4 NPs) were prepared as an ovarian tumor specific bimodal imaging nanoprobe.	ferryl iron	81-86	reticulon 4 receptor	Homo sapiens	30-33
30274135-4	2018	In this study, Cy5.5-labeled, NGR-conjugated iron oxide nanoparticles (Cy5.5-NGR-Fe3O4 NPs) were prepared as an ovarian tumor specific bimodal imaging nanoprobe.	ferryl iron	81-86	reticulon 4 receptor	Homo sapiens	77-80
30460410-4	2018	The resulting Fe3O4/KAP is shown to be a viable magnetic sorbent for various organic materials such as the phenylurea herbicides (PUHs), including metoxuron, monuron, chlortoluron, monolinuron and buturon, and also for various phthalates, polycyclic aromatic hydrocarbons and chlorophenols.	ferryl iron	14-19	napsin A aspartic peptidase	Homo sapiens	20-23
30125878-0	2018	An enzyme-free electrochemical biosensor combining target recycling with Fe3O4/CeO2@Au nanocatalysts for microRNA-21 detection.	ferryl iron	73-78	microRNA 21	Homo sapiens	105-116
30125878-1	2018	In this study, an electrochemical biosensor was proposed for microRNA-21 detection based on Fe3O4/CeO2 @Au magnetite nanoparticles (Fe3O4/CeO2 @Au MNPs) as nanocatalyst and catalytic hairpin assembly (CHA) for signal application.	ferryl iron	92-97	microRNA 21	Homo sapiens	61-72
30125878-1	2018	In this study, an electrochemical biosensor was proposed for microRNA-21 detection based on Fe3O4/CeO2 @Au magnetite nanoparticles (Fe3O4/CeO2 @Au MNPs) as nanocatalyst and catalytic hairpin assembly (CHA) for signal application.	ferryl iron	132-137	microRNA 21	Homo sapiens	61-72
30581720-5	2018	The unique structure and composition of the Fe3O4/Au DSNFs endows them with a high r 1 relaxivity (3.22 mM-1 s-1) and photothermal conversion efficiency (82.7%), affording their uses as a theranostic nanoplatform for multimode MR/CT/PA imaging and combination PTT/RT of tumors with improved therapeutic efficacy, which is important for translational nanomedicine applications.	ferryl iron	44-49	ct/pa	None	230-235
33429596-6	2018	Furthermore, Fe3O4@PDA-siRNA@MSCs NPs delivering siRNA against Plk1 gene could inhibit the expression of endogenous Plk1 gene and cause obvious apoptosis in DU145 cells.	ferryl iron	13-18	polo like kinase 1	Homo sapiens	63-67
33429596-6	2018	Furthermore, Fe3O4@PDA-siRNA@MSCs NPs delivering siRNA against Plk1 gene could inhibit the expression of endogenous Plk1 gene and cause obvious apoptosis in DU145 cells.	ferryl iron	13-18	polo like kinase 1	Homo sapiens	116-120
30132574-4	2018	In the current study, PEI@Fe3O4 nanoparticles (NPs) were used to deliver NRSF small interfering (si)RNA and SHH siRNA to hADSCs and hAMSCs.	ferryl iron	26-31	RE1 silencing transcription factor	Homo sapiens	73-77
30359001-5	2018	Access to large-scale, phase-pure BNSL colloids offers vast opportunities for investigating their physiochemical properties, as exemplified by AB13-type CoFe2O4-Fe3O4 binary superparticles.	ferryl iron	161-166	NBPF member 1	Homo sapiens	143-147
30132574-0	2018	The differentiation of human MSCs derived from adipose and amniotic tissues into insulin-producing cells, induced by PEI@Fe3O4 nanoparticles-mediated NRSF and SHH silencing.	ferryl iron	121-126	insulin	Homo sapiens	81-88
30151686-1	2018	A novel platform for carbamate-based pesticide quantification using a chitosan/magnetic iron oxide (Chit-Fe3O4) nanocomposite as a glassy carbon electrode (GCE) modifier is shown for an analytical methodology for determination of bendiocarb (BND).	ferryl iron	105-110	chitinase 1	Homo sapiens	100-104
30151686-2	2018	The BND oxidation signal using GCE/Chit-Fe3O4 compared with bare GCE was catalyzed, showing a 37.5% of current increase with the peak potential towards less positive values, showing method"s increased sensitivity and selectivity.	ferryl iron	40-45	chitinase 1	Homo sapiens	35-39
30151686-4	2018	The proposed electroanalytical methodology was successfully applied for BND quantification in natural raw waters without any sample pretreatment, proving that the GCE/Chit-Fe3O4 modified electrode showed great potential for BND determination in complex samples.	ferryl iron	172-177	chitinase 1	Homo sapiens	167-171
30209767-3	2018	The maximum adsorption capacity of Fe3O4@MOF-100(Fe) for diclofenac sodium can reach 377.36 mg L-1, which was higher than most of the adsorbents reported.	ferryl iron	35-40	immunoglobulin kappa variable 1-16	Homo sapiens	95-98
30132574-0	2018	The differentiation of human MSCs derived from adipose and amniotic tissues into insulin-producing cells, induced by PEI@Fe3O4 nanoparticles-mediated NRSF and SHH silencing.	ferryl iron	121-126	RE1 silencing transcription factor	Homo sapiens	150-154
30132574-4	2018	In the current study, PEI@Fe3O4 nanoparticles (NPs) were used to deliver NRSF small interfering (si)RNA and SHH siRNA to hADSCs and hAMSCs.	ferryl iron	26-31	sonic hedgehog signaling molecule	Homo sapiens	108-111
30132574-0	2018	The differentiation of human MSCs derived from adipose and amniotic tissues into insulin-producing cells, induced by PEI@Fe3O4 nanoparticles-mediated NRSF and SHH silencing.	ferryl iron	121-126	sonic hedgehog signaling molecule	Homo sapiens	159-162
30132574-8	2018	These findings indicated that hADSCs and hAMSCs may be induced to differentiate into IPCs via PEI@Fe3O4 NP-mediated NRSF and SHH silencing.	ferryl iron	98-103	RE1 silencing transcription factor	Homo sapiens	116-120
29940528-2	2018	The rGO-PDTC/Fe3O4 nanocomposite was prepared via a novel synthesis route that includes GO bromination, nucleophilic substitution of polyethylenimine (PEI), the reaction with carbon disulphide (CS2) and Fe3O4 nanoparticle loading.	ferryl iron	13-18	chorionic somatomammotropin hormone 2	Homo sapiens	194-197
29940528-4	2018	N2 adsorption-desorption results revealed that rGO-PDTC/Fe3O4 nanocomposite exhibited high BET surface area (194.8 m2/g) and large pore volume (0.33 cm3/g) which are crucial to the function of adsorbent.	ferryl iron	56-61	delta/notch like EGF repeat containing	Homo sapiens	91-94
29852227-0	2018	Removal of Pb(II) ions from aqueous media using epichlorohydrin crosslinked chitosan Schiff"s base@Fe3O4 (ECCSB@Fe3O4).	ferryl iron	99-104	submaxillary gland androgen regulated protein 3B	Homo sapiens	11-17
29852227-0	2018	Removal of Pb(II) ions from aqueous media using epichlorohydrin crosslinked chitosan Schiff"s base@Fe3O4 (ECCSB@Fe3O4).	ferryl iron	112-117	submaxillary gland androgen regulated protein 3B	Homo sapiens	11-17
30151523-9	2018	H&amp;E staining showed Fe3O4@PDA NP-labeled NK cells, under a magnetic field, had higher intra-tumoral iron density and increased accumulation of CD56+ NK cells.	ferryl iron	24-29	neural cell adhesion molecule 1	Homo sapiens	147-151
30224683-1	2018	In this study, we report on the fabrication of multilayered tri-functional magnetic-SERS-fluorescence nanoprobes (MF-SERS particles) containing clustered superparamagnetic Fe3O4 nanoparticles (NPs), silver NPs, and a fluorescent silica layer.	ferryl iron	172-177	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	60-63
30224683-1	2018	In this study, we report on the fabrication of multilayered tri-functional magnetic-SERS-fluorescence nanoprobes (MF-SERS particles) containing clustered superparamagnetic Fe3O4 nanoparticles (NPs), silver NPs, and a fluorescent silica layer.	ferryl iron	172-177	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	84-88
30224683-1	2018	In this study, we report on the fabrication of multilayered tri-functional magnetic-SERS-fluorescence nanoprobes (MF-SERS particles) containing clustered superparamagnetic Fe3O4 nanoparticles (NPs), silver NPs, and a fluorescent silica layer.	ferryl iron	172-177	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	117-121
29891322-0	2018	Morphological, electrical &amp; antibacterial properties of trilayered Cs/PAA/PPy bionanocomposites hydrogel based on Fe3O4-NPs.	ferryl iron	118-123	pancreatic polypeptide	Homo sapiens	78-81
30194494-2	2018	Lysozyme-conjugated Fe3O4 nanoparticles (Lys-Fe3O4NPs) were used to capture alpha-LA on the surface of the SPCEs which then is trapped in an immunosandwich using secondary antibodies labeled with ferrocene-modified gold nanoparticles.	ferryl iron	20-25	lactalbumin alpha	Homo sapiens	76-84
29890419-1	2018	Effect of dosing ferroferric oxide (Fe3O4) on the anaerobic treatment of azo dye Reactive Red 2 (RR2) was investigated in two anaerobic sequencing batch reactors (ASBRs).	ferryl iron	36-41	adenosine deaminase RNA specific B2 (inactive)	Homo sapiens	90-95
30019133-1	2018	A novel chitosan/ceria/iron oxide (CS/ceria/Fe3O4) nano-composite adsorbent was synthesized for removal of Cr(VI) and Co(II) ions from aqueous systems in a batch system.	ferryl iron	44-49	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	118-124
29853027-0	2018	Highly sensitive fluorescent detection of p53 protein based on DNA functionalized Fe3O4 nanoparticles.	ferryl iron	82-87	tumor protein p53	Homo sapiens	42-45
29778001-9	2018	This aptasensor showed a wide linear range of 0.1 pg mL-1-15 ng mL-1 with a low detection limit of 0.03 pg mL-1, remaining competitive against other ones, and also demonstrating the PG-Fe3O4 NPs have promising potential for catalysis and bioassays.	ferryl iron	185-190	L1 cell adhesion molecule	Mus musculus	53-57
29738787-9	2018	Cell surface expression of SR-B1 was reduced following all Fe3O4 NPs exposures, while only NPs with an LDL-BC enhanced mitochondrial membrane potential.	ferryl iron	59-64	scavenger receptor class B member 1	Homo sapiens	27-32
29778001-9	2018	This aptasensor showed a wide linear range of 0.1 pg mL-1-15 ng mL-1 with a low detection limit of 0.03 pg mL-1, remaining competitive against other ones, and also demonstrating the PG-Fe3O4 NPs have promising potential for catalysis and bioassays.	ferryl iron	185-190	L1 cell adhesion molecule	Mus musculus	64-68
29778001-9	2018	This aptasensor showed a wide linear range of 0.1 pg mL-1-15 ng mL-1 with a low detection limit of 0.03 pg mL-1, remaining competitive against other ones, and also demonstrating the PG-Fe3O4 NPs have promising potential for catalysis and bioassays.	ferryl iron	185-190	L1 cell adhesion molecule	Mus musculus	64-68
30128777-1	2018	A novel sorbent consisting of WO3 and Fe3O4 is described for preconcentration of Pb(II).	ferryl iron	38-43	submaxillary gland androgen regulated protein 3B	Homo sapiens	81-87
29784385-6	2018	A simplified protocol based on cell-aptamer interaction has been developed in which core-shell (Au@Fe3O4) nanoparticles (CSNs) were functionalized with a mucin 1 (MUC1) specific aptamer (Apt1) to capture cells through the interaction between Apt1 and overexpressed protein (MUC1) on the surface of the tumor cells.	ferryl iron	99-104	mucin 1, cell surface associated	Homo sapiens	163-167
29966987-8	2018	Saturation magnetization value as obtained from hysteresis loop is 105 and 75 Am2/kg for Fe3O4/CMCS and MnFe2O4/CMCS hydrogel, respectively.	ferryl iron	89-94	G protein signaling modulator 2	Homo sapiens	95-99
30081589-7	2018	Results indicated that the etched Fe3O4/FePc microspheres would improve the crystallization degree of c-PEN, due to their much more micro/mesoporous structures than that of original Fe3O4/FePc.	ferryl iron	34-39	proprotein convertase subtilisin/kexin type 1 inhibitor	Homo sapiens	104-107
30081589-8	2018	Then, Fe3O4/FePc hybrid microspheres reinforced PEN composite films were prepared and their interfacial compatibility was monitored using an SEM.	ferryl iron	6-11	proprotein convertase subtilisin/kexin type 1 inhibitor	Homo sapiens	48-51
30095425-4	2018	The mean diameter of fabricated Fe3O4@SPI-BSA NPs was &lt;120 nm (PDI, 0.187).	ferryl iron	32-37	chromogranin A	Homo sapiens	38-41
30095425-5	2018	Inulinase was covalently immobilised successfully through glutaraldehyde on Fe3O4@SPI-BSA NPs with 80% enzyme loading.	ferryl iron	76-81	chromogranin A	Homo sapiens	82-85
29966987-15	2018	The effect of applied magnetic field on drug release for Fe3O4/CMCS was highest compared to MnFe2O4/CMCS.	ferryl iron	57-62	G protein signaling modulator 2	Homo sapiens	63-67
30224987-6	2018	Furthermore, the results of in vitro alkaline phosphatase (ALP) activity at 7 and 14 days and alizarin red S staining at 14 days showed that the Fe3O4/PDA coating on Ti promoted the osteogenic differentiation of hBMSCs.	ferryl iron	145-150	alkaline phosphatase, placental	Homo sapiens	37-57
30224987-6	2018	Furthermore, the results of in vitro alkaline phosphatase (ALP) activity at 7 and 14 days and alizarin red S staining at 14 days showed that the Fe3O4/PDA coating on Ti promoted the osteogenic differentiation of hBMSCs.	ferryl iron	145-150	alkaline phosphatase, placental	Homo sapiens	59-62
30224987-7	2018	Moreover, hBMSCs co-cultured with the Fe3O4/PDA-coated Ti for approximately 14 days also exhibited a significantly higher mRNA expression level of ALP, osteocalcin and runt-related transcription factor-2 (RUNX2).	ferryl iron	38-43	alkaline phosphatase, placental	Homo sapiens	147-150
30224987-7	2018	Moreover, hBMSCs co-cultured with the Fe3O4/PDA-coated Ti for approximately 14 days also exhibited a significantly higher mRNA expression level of ALP, osteocalcin and runt-related transcription factor-2 (RUNX2).	ferryl iron	38-43	bone gamma-carboxyglutamate protein	Homo sapiens	152-163
30224987-7	2018	Moreover, hBMSCs co-cultured with the Fe3O4/PDA-coated Ti for approximately 14 days also exhibited a significantly higher mRNA expression level of ALP, osteocalcin and runt-related transcription factor-2 (RUNX2).	ferryl iron	38-43	RUNX family transcription factor 2	Homo sapiens	168-203
30224987-7	2018	Moreover, hBMSCs co-cultured with the Fe3O4/PDA-coated Ti for approximately 14 days also exhibited a significantly higher mRNA expression level of ALP, osteocalcin and runt-related transcription factor-2 (RUNX2).	ferryl iron	38-43	RUNX family transcription factor 2	Homo sapiens	205-210
30065155-3	2018	Here, polyethyleneimine (PEI)-coated Fe3O4 nanoparticles (NPs) have been developed and applied for siRNA delivery into GBM cells to silence repressor element 1-silencing transcription factor (REST).	ferryl iron	37-42	RE1 silencing transcription factor	Homo sapiens	140-190
29878757-0	2018	Photothermal-Activatable Fe3O4 Superparticle Nanodrug Carriers with PD-L1 Immune Checkpoint Blockade for Anti-metastatic Cancer Immunotherapy.	ferryl iron	25-30	CD274 molecule	Homo sapiens	68-73
30043136-14	2018	A high sensitive voltammetric immunoassay method has been used for detecting CEA, It is based on a self-assembled magnetic nanocomposite (Au NPs@ZrHCF@Fe3O4) as multifunctional signal amplification platform.	ferryl iron	151-156	CEA cell adhesion molecule 3	Homo sapiens	77-80
28699008-1	2018	Magnetite (Fe3O4) nanoparticle-encapsulated mesoporous carbon nanocomposite was fabricated from Fe-based metal-organic framework (MOF) (MIL-102) through carbonization.	ferryl iron	11-16	lysine acetyltransferase 8	Homo sapiens	105-134
28699008-2	2018	It was found that Fe-based MOF (MIL-102) is a potential precursor for the fabrication of hexagonal mesoporous carbon nanodisk functionalized with Fe3O4 nanoparticles.	ferryl iron	146-151	lysine acetyltransferase 8	Homo sapiens	27-30
29805549-0	2018	Contrast-enhanced computed tomography combined with Chitosan-Fe3O4 nanoparticles targeting fibroblast growth factor receptor and vascular endothelial growth factor receptor in the screening of early esophageal cancer.	ferryl iron	61-66	kinase insert domain receptor	Homo sapiens	129-172
29904421-3	2018	In the present study, a novel nano-sized contrast agent of chistosan/Fe3O4-enclosed bispecific antibodies (BsAbCENS) was introduced, which targeted carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) in lung cancer cells.	ferryl iron	69-74	CEA cell adhesion molecule 3	Homo sapiens	148-179
29904421-3	2018	In the present study, a novel nano-sized contrast agent of chistosan/Fe3O4-enclosed bispecific antibodies (BsAbCENS) was introduced, which targeted carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) in lung cancer cells.	ferryl iron	69-74	enolase 2	Homo sapiens	184-207
29904421-3	2018	In the present study, a novel nano-sized contrast agent of chistosan/Fe3O4-enclosed bispecific antibodies (BsAbCENS) was introduced, which targeted carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) in lung cancer cells.	ferryl iron	69-74	enolase 2	Homo sapiens	209-212
29805549-4	2018	A Chitosan-Fe3O4-parceled bispecific antibody targeting FGFR and VEGFR was produced and its affinity to esophageal cancer cells was determined both in vitro and in vivo.	ferryl iron	11-16	kinase insert domain receptor	Homo sapiens	65-70
29737838-5	2018	After 1000 cycles at current densities as high as 1 and 2 A g-1, charge capacities of the as-synthesized nanocomposite maintain 971 and 715 mA h g-1, respectively, much higher than those of reported Fe3O4-based anode materials.	ferryl iron	199-204	prostaglandin D2 receptor	Homo sapiens	47-63
29101636-11	2018	Optical imaging performed in tumor-bearing mice showed increased fluorescent signal in mammary gland of animals injected by LyP-1-Fe3O4-Cy5.5 but not Ctlpep- Fe3O4-Cy5.5.	ferryl iron	130-135	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	124-129
29673159-1	2018	Efficient and general protocols for the O-tert-boc protection and O-arylation of phenols were developed in this paper using a recyclable magnetic Fe3O4-Co3O4 nanocatalyst (Nano-Fe-Co), which is easily accessible via simple wet impregnation techniques in aqueous mediums from inexpensive precursors.	ferryl iron	146-151	BOC cell adhesion associated, oncogene regulated	Homo sapiens	47-50
29501199-0	2018	Development of alanine aminotransferase reactor based on polymer@Fe3O4 nanoparticles for enzyme inhibitors screening by chiral ligand exchange capillary electrophoresis.	ferryl iron	65-70	glutamic--pyruvic transaminase	Homo sapiens	15-39
29700546-2	2018	Here, we present luminous Eu(iii) complex-functionalized Fe3O4 nanoparticles encapsulated into zeolitic imidazolate framework materials (nano-ZIF-8) and successfully employ this nano-MOF as a fluorescence probe for selective and sensitive detection of ClO- and SCN-.	ferryl iron	57-62	sorcin	Homo sapiens	252-264
29496224-10	2018	The presence of Fe3O4 nanoparticles in the spherical CHX particles was confirmed with SEM, EDX, and TGA.	ferryl iron	16-21	T-box transcription factor 1	Homo sapiens	100-103
29407928-2	2018	In this study, N,N"-bis (acetyl acetone) ethylenediimine (Fe3O4@SiO2-EDN) was synthesized and applied for dispersive solid phase extraction of copper in water and cereal samples followed by FAAS.	ferryl iron	58-63	ribonuclease A family member 2	Homo sapiens	69-72
29719396-6	2018	Results: The inhibitory and apoptotic rates of Fe3O4@Au-C225 composite-targeted MNPs-mediated combined hyperthermia (MFH+NIR) group were significantly higher than other groups in vitro and the marked upregulation of caspase-3, caspase-8, and caspase-9 expression indicated excellent antitumor effect by inducing intrinsic apoptosis.	ferryl iron	47-52	caspase 3	Homo sapiens	216-225
29719396-6	2018	Results: The inhibitory and apoptotic rates of Fe3O4@Au-C225 composite-targeted MNPs-mediated combined hyperthermia (MFH+NIR) group were significantly higher than other groups in vitro and the marked upregulation of caspase-3, caspase-8, and caspase-9 expression indicated excellent antitumor effect by inducing intrinsic apoptosis.	ferryl iron	47-52	caspase 8	Homo sapiens	227-236
29719396-6	2018	Results: The inhibitory and apoptotic rates of Fe3O4@Au-C225 composite-targeted MNPs-mediated combined hyperthermia (MFH+NIR) group were significantly higher than other groups in vitro and the marked upregulation of caspase-3, caspase-8, and caspase-9 expression indicated excellent antitumor effect by inducing intrinsic apoptosis.	ferryl iron	47-52	caspase 9	Homo sapiens	242-251
29156408-4	2018	The ds-DNA/p(L-Cys)/Fe3O4 NPs-GO/CPE exhibited an increase in peak currents and the electron transfer kinetics and decrease in the overpotential for the oxidation reaction of A and G. Under the optimal conditions a linear relationship is figured out between the peak current and the analytes" concentrations on a range of 0.01-30.0muM and 0.01-25.0muM for simultaneous determination of A and G, with detection limits of 3.48 and 1.59nM, respectively.	ferryl iron	20-25	carboxypeptidase E	Homo sapiens	33-36
29584682-5	2018	Compared with bare electrode and RGO/GCE, the oxidation peak current (ipa) on the NH2-Fe3O4/RGO/GCE increase significantly, owing to the synergistic effect between NH2-Fe3O4 NPs and RGO sheets.	ferryl iron	86-91	glycine decarboxylase	Homo sapiens	37-40
29154996-5	2018	SDS-PAGE and activity data showed His-tagged hSOD1 specifically bound to Fe3O4/PMG/IDA-Ni2+, and there was no significant competition for binding between final and three intermediate products.	ferryl iron	73-78	superoxide dismutase 1	Homo sapiens	45-50
29332833-6	2018	The adsorption capacity of Fe3O4-GO@PAAPBA towards ovalbumin (OVA) and transferrin (Trf) is 471mgg-1 and 450mgg-1, respectively.	ferryl iron	27-32	transferrin	Homo sapiens	71-82
29332833-6	2018	The adsorption capacity of Fe3O4-GO@PAAPBA towards ovalbumin (OVA) and transferrin (Trf) is 471mgg-1 and 450mgg-1, respectively.	ferryl iron	27-32	transferrin	Homo sapiens	84-87
31458619-6	2018	The adsorption capacities of Fe3O4@SiO2@mC-H2O2 for Cu(II) and Pb(II) were calculated to be 86.5 and 156 mg g-1, respectively.	ferryl iron	29-34	submaxillary gland androgen regulated protein 3B	Homo sapiens	52-69
31458619-7	2018	Under optimal conditions, the adsorption isotherm of Cu(II) and Pb(II) onto Fe3O4@SiO2@mC-H2O2 fitted the Langmuir model and the adsorption kinetic was well-correlated with the pseudo-second-order model.	ferryl iron	76-81	submaxillary gland androgen regulated protein 3B	Homo sapiens	53-70
31458619-8	2018	Besides, Fe3O4@SiO2@mC-H2O2 exhibited fast removal dynamics (within less than 1 min) for Cu(II) and Pb(II), demonstrating great application potential in wastewater treatment.	ferryl iron	9-14	submaxillary gland androgen regulated protein 3B	Homo sapiens	89-106
29584682-5	2018	Compared with bare electrode and RGO/GCE, the oxidation peak current (ipa) on the NH2-Fe3O4/RGO/GCE increase significantly, owing to the synergistic effect between NH2-Fe3O4 NPs and RGO sheets.	ferryl iron	86-91	glycine decarboxylase	Homo sapiens	96-99
29415453-4	2018	The coating amount of PAA onto the surface of Fe3O4 (measured by TGA) is about 40% (w/w).	ferryl iron	46-51	T-box transcription factor 1	Homo sapiens	65-68
29436216-3	2018	In our study, TNF-alpha and IFN-gamma were coimmobilized on polystyrene material (PSt) or Fe3O4-oleic acid nanoparticles (NPs).	ferryl iron	90-95	interferon gamma	Homo sapiens	28-37
29663921-7	2018	The HA/CSO-SS-Hex/Fe3O4/PTX micelle was stable under physiological conditions, while it was sensitive to release the loaded drug in the presence of 10 mM glutathione (GSH).	ferryl iron	18-23	hematopoietically expressed homeobox	Homo sapiens	14-17
29663921-9	2018	Cell viability tests revealed that HA/CSO-SS-Hex/Fe3O4/PTX micelle displayed enhanced cytotoxicity against A549, B16F10 and HepG2 cell lines compared to non-targeted formulations of PTX.	ferryl iron	49-54	hematopoietically expressed homeobox	Homo sapiens	45-48
29663921-12	2018	Thus, the novel HA/CSO-SS-Hex/Fe3O4/PTX micelle is highly effective for targeted drug delivery and might have potential implications for the chemotherapy of primary tumors and their metastases.	ferryl iron	30-35	hematopoietically expressed homeobox	Homo sapiens	26-29
29107049-2	2018	In this study, I addressed this issue and focused on the synthesis and characterization of pH-responsive Fe3O4@SiO2(FITC)-BTN/folic acid/DOX multifunctional nanoparticles aiming to increase drug accumulation in malignancies with both dual active targeting and endosomal drug release properties.	ferryl iron	105-110	butyrophilin subfamily 1 member A1	Homo sapiens	122-125
29310271-0	2018	A novel peptide/Fe3O4@SiO2-Au nanocomposite-based fluorescence biosensor for the highly selective and sensitive detection of prostate-specific antigen.	ferryl iron	16-21	kallikrein related peptidase 3	Homo sapiens	125-150
29310271-2	2018	Here, we present a novel peptide/Fe3O4@SiO2-Au nanocomposite-based fluorescence biosensor for highly selective and sensitive detection of PSA.	ferryl iron	33-38	kallikrein related peptidase 3	Homo sapiens	138-141
29376371-5	2018	The densities of PS/Fe3O4 and PSF/Fe3O4 particles were significantly lowered from that of the pure Fe3O4 particle after Pickering-emulsion polymerization and foaming treatment.	ferryl iron	34-39	insulin like growth factor binding protein 7	Homo sapiens	30-33
29376371-5	2018	The densities of PS/Fe3O4 and PSF/Fe3O4 particles were significantly lowered from that of the pure Fe3O4 particle after Pickering-emulsion polymerization and foaming treatment.	ferryl iron	34-39	insulin like growth factor binding protein 7	Homo sapiens	30-33
29376371-11	2018	The suspensions of PS/Fe3O4 and PSF/Fe3O4 showed remarkably improved stability against sedimentation, much better than the bare Fe3O4 particle suspension because of the reduced density mismatch between the nanoparticles and the carrier medium as well as the surface topology change.	ferryl iron	36-41	insulin like growth factor binding protein 7	Homo sapiens	32-35
29376371-11	2018	The suspensions of PS/Fe3O4 and PSF/Fe3O4 showed remarkably improved stability against sedimentation, much better than the bare Fe3O4 particle suspension because of the reduced density mismatch between the nanoparticles and the carrier medium as well as the surface topology change.	ferryl iron	36-41	insulin like growth factor binding protein 7	Homo sapiens	32-35
29424699-0	2018	Cube-like Fe3O4@SiO2@Au@Ag magnetic nanoparticles: a highly efficient SERS substrate for detection of pesticide.	ferryl iron	10-15	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	70-74
29424699-1	2018	As a novel SERS nanocomposities, cube-like Fe3O4@SiO2@Au@Ag magnetic nanoparticles have been synthesized for the first time.	ferryl iron	43-48	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	11-15
29165044-0	2018	LyP-1-conjugated Fe3O4 nanoparticles suppress tumor growth by magnetic induction hyperthermia.	ferryl iron	17-22	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	0-5
28993297-2	2018	The Fe3O4/CS-PEI composite was characterized by SEM, XRD, TGA and FT-IR analysis.	ferryl iron	4-9	T-box transcription factor 1	Homo sapiens	58-61
29080821-1	2018	In this work, poly(carboxybetaine methacrylate) as an extremely hydrophilic polymer was modified on superparamagnetic Fe3O4 nanoparticles (pCB-Fe3O4), which were employed to immobilize porcine pancreatic lipase.	ferryl iron	118-123	pancreatic lipase	Mus musculus	193-210
29080821-1	2018	In this work, poly(carboxybetaine methacrylate) as an extremely hydrophilic polymer was modified on superparamagnetic Fe3O4 nanoparticles (pCB-Fe3O4), which were employed to immobilize porcine pancreatic lipase.	ferryl iron	143-148	pancreatic lipase	Mus musculus	193-210
29080821-8	2018	These results showed that pCB-Fe3O4 composite particles had higher efficiency and improved stability for lipase immobilization, which are more promising for industrial scale up of biocatalytic systems with excellent biocompatibility.	ferryl iron	30-35	lipase, endothelial	Mus musculus	105-111
29165044-6	2018	The contents of Fe3O4 in the PEG-SPIONs and LyP-1-SPIONs were about 94.24 and 89.26%, respectively.	ferryl iron	16-21	progestagen associated endometrial protein	Homo sapiens	29-32
29334395-2	2018	Here, we utilize the normal incidence X-ray standing wave (NIXSW) technique to precisely determine the three dimensional geometry of Ag1 and Cu1 adatoms on Fe3O4(001).	ferryl iron	156-161	NBPF member 10	Homo sapiens	133-136
29035802-3	2018	The Fe3O4@Ph-SO3H was characterized using FTIR, TGA, PXRD, SEM, TEM, VSM and EDX techniques.	ferryl iron	4-9	T-box transcription factor 1	Homo sapiens	48-51
28873652-3	2018	The selectivity experiment demonstrated the higher selectivity of Fe3O4@SiO2/GO/beta-CD toward 5 PGR compounds than that of Fe3O4@SiO2/GO.	ferryl iron	124-129	progesterone receptor	Homo sapiens	97-100
29136869-0	2018	Facile synthesis of Fe3O4@PDA core-shell microspheres functionalized with various metal ions: A systematic comparison of commonly-used metal ions for IMAC enrichment.	ferryl iron	20-25	C-C motif chemokine ligand 26	Homo sapiens	150-154
28800506-0	2018	Ni(OH)2/NGQDs-based electrochemiluminescence immunosensor for prostate specific antigen detection by coupling resonance energy transfer with Fe3O4@MnO2 composites.	ferryl iron	141-146	kallikrein related peptidase 3	Homo sapiens	62-87
28873652-3	2018	The selectivity experiment demonstrated the higher selectivity of Fe3O4@SiO2/GO/beta-CD toward 5 PGR compounds than that of Fe3O4@SiO2/GO.	ferryl iron	66-71	progesterone receptor	Homo sapiens	97-100
29237264-4	2018	The pH-sensitive dye was linked through a peptide substrate of matrix metalloprotease-9 (MMP-9) with Fe3O4 nanoparticles to establish a Forster resonance energy transfer (FRET) system for sensing the pH of the tumor microenvironment.	ferryl iron	101-106	matrix metallopeptidase 9	Homo sapiens	89-94
29321571-0	2018	Thrombin@Fe3O4 nanoparticles for use as a hemostatic agent in internal bleeding.	ferryl iron	9-14	coagulation factor II, thrombin	Homo sapiens	0-8
29873527-0	2018	Magnetic Fe3O4@MCM-41 core-shell nanoparticles functionalized with thiol silane for efficient l-asparaginase immobilization.	ferryl iron	9-14	asparaginase and isoaspartyl peptidase 1	Homo sapiens	94-108
29305666-7	2018	In fact, more than 80% of 99mTc-DTPA-TZMB@Fe3O4 nanoparticles seems to be cleared by the renal pathway but the implanted tumor whose seems to increase the expression of HER2 receptors enhancing the uptake by all other organs.	ferryl iron	42-47	erb-b2 receptor tyrosine kinase 2	Mus musculus	169-173
29873527-4	2018	In addition, surface of Fe3O4@MCM-41 magnetic nanoparticles was functionalized with 3-mercaptopropyltrimethoxysilane (MPTMS) to enhance stability of l-ASNase.	ferryl iron	24-29	asparaginase and isoaspartyl peptidase 1	Homo sapiens	149-157
29873527-6	2018	l-ASNase was covalently immobilized onto the thiol-functionalized Fe3O4@MCM-41 magnetic nanoparticles.	ferryl iron	66-71	asparaginase and isoaspartyl peptidase 1	Homo sapiens	0-8
29149993-8	2018	Here, we present a novel analytical nanosensor applicable to quantification of GCPII in human whole blood consisted of Fe3O4@Ag magnetic nanocomposite surface-functionalized by an artificial antibody (low-molecular-weight GCPII synthetic inhibitor).	ferryl iron	119-124	folate hydrolase 1	Homo sapiens	79-84
29468888-4	2018	We used the double emulsion method (water/oil/water) to prepare 5FU-encapsulated Fe3O4 magnetic nanoparticles modified with PCL-PEG-PCL copolymer.	ferryl iron	81-86	PHD finger protein 1	Homo sapiens	124-127
29873527-12	2018	Thereby, the results confirmed that thiol-functionalized Fe3O4@MCM-41 magnetic nanoparticles had high efficiency for l-ASNase immobilization and improved stability of L-ASNase.	ferryl iron	57-62	asparaginase and isoaspartyl peptidase 1	Homo sapiens	117-125
31565300-0	2018	Synthesis and Application of Polypyrrole/Fe3O4 Nanosize Magnetic Adsorbent for Efficient Separation of Hg2+ from Aqueous Solution.	ferryl iron	41-46	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	103-106
29873527-12	2018	Thereby, the results confirmed that thiol-functionalized Fe3O4@MCM-41 magnetic nanoparticles had high efficiency for l-ASNase immobilization and improved stability of L-ASNase.	ferryl iron	57-62	asparaginase and isoaspartyl peptidase 1	Homo sapiens	167-175
29995570-0	2018	Development of Fe3O4/Ag core/shell-based multifunctional immunomagnetic nanoparticles for isolation and detection of CD34+ stem cells.	ferryl iron	15-20	CD34 molecule	Homo sapiens	117-121
28942255-7	2017	Under the optimum condition (initial Pb(II) concentration = 110 mg L-1, MDA-Fe3O4 dosage = 0.49 g L-1, pH = 5 and temperature = 30  C) a removal percentage of 85.6% was obtained.	ferryl iron	76-81	immunoglobulin kappa variable 1-16	Homo sapiens	98-101
28942255-10	2017	The adsorption rate of Pb(II) ions onto MDA-Fe3O4 was in good agreement with the pseudo-second-order model (R2 = 0.999; k2 = 4.7 x 10-4 g mg-1min-1).	ferryl iron	44-49	submaxillary gland androgen regulated protein 3B	Homo sapiens	23-29
29022219-3	2017	The physical and chemical properties of BiVO4-Fe3O4 were characterized by UV-vis-DRS, SEM, XRD, FTIR, and BET.	ferryl iron	46-51	delta/notch like EGF repeat containing	Homo sapiens	106-109
28283455-0	2017	Synthesis of water-dispersible poly-l-lysine-functionalized magnetic Fe3O4-(GO-MWCNTs) nanocomposite hybrid with a large surface area for high-efficiency removal of tartrazine and Pb(II).	ferryl iron	69-74	submaxillary gland androgen regulated protein 3B	Homo sapiens	180-186
28283455-3	2017	The PLL-Fe3O4-(GO-MWCNTs) hybrid composite exhibited excellent adsorption performance for the removal of a dye (tartrazine) and a heave metal (Pb(II)).	ferryl iron	8-13	submaxillary gland androgen regulated protein 3B	Homo sapiens	143-149
28732931-11	2017	For example, cell viability of Fe3O4@Cs-sPEG decreased from 44+-2% to 36+-1.9% at a concentration of 5 (mug/ml) as the pH varied from 7.4 to 5.8.	ferryl iron	31-36	striated muscle enriched protein kinase	Homo sapiens	40-44
28711619-0	2017	Adsorption of Pb(II) ions from aqueous environment using eco-friendly chitosan schiff"s base@Fe3O4 (CSB@Fe3O4) as an adsorbent; kinetics, isotherm and thermodynamic studies.	ferryl iron	93-98	submaxillary gland androgen regulated protein 3B	Homo sapiens	14-20
28710928-2	2017	The Fe3O4 magnetic nanoparticles (Fe3O4 MNPs) modified by SiO2/aminopropyl trimethoxy silane/cyanuric chloride (Fe3O4@SiO2-APTMS/CC) utilized for anchoring metformin-cobalt complex (Fe3O4 Ms@SiO2-APTMS/CC/Met@Co(II)).	ferryl iron	4-9	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	209-215
28710928-2	2017	The Fe3O4 magnetic nanoparticles (Fe3O4 MNPs) modified by SiO2/aminopropyl trimethoxy silane/cyanuric chloride (Fe3O4@SiO2-APTMS/CC) utilized for anchoring metformin-cobalt complex (Fe3O4 Ms@SiO2-APTMS/CC/Met@Co(II)).	ferryl iron	34-39	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	209-215
28710928-2	2017	The Fe3O4 magnetic nanoparticles (Fe3O4 MNPs) modified by SiO2/aminopropyl trimethoxy silane/cyanuric chloride (Fe3O4@SiO2-APTMS/CC) utilized for anchoring metformin-cobalt complex (Fe3O4 Ms@SiO2-APTMS/CC/Met@Co(II)).	ferryl iron	34-39	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	209-215
29112141-0	2017	Optimizing Low-Concentration Mercury Removal from Aqueous Solutions by Reduced Graphene Oxide-Supported Fe3O4 Composites with the Aid of an Artificial Neural Network and Genetic Algorithm.	ferryl iron	104-109	activation induced cytidine deaminase	Homo sapiens	130-133
29112141-1	2017	Reduced graphene oxide-supported Fe3O4 (Fe3O4/rGO) composites were applied in this study to remove low-concentration mercury from aqueous solutions with the aid of an artificial neural network (ANN) modeling and genetic algorithm (GA) optimization.	ferryl iron	33-38	activation induced cytidine deaminase	Homo sapiens	157-160
29112141-1	2017	Reduced graphene oxide-supported Fe3O4 (Fe3O4/rGO) composites were applied in this study to remove low-concentration mercury from aqueous solutions with the aid of an artificial neural network (ANN) modeling and genetic algorithm (GA) optimization.	ferryl iron	40-45	activation induced cytidine deaminase	Homo sapiens	157-160
28866214-8	2017	It has been found that Ni(II)-immobilized Fe3O4@Histidine magnetic nanoparticles present negligible nonspecific protein adsorption and high His-tag protein binding capacity The average binding capacity (MW 42k Da), is 700+-25mug mg-1 (protein/Fe3O4@Histidine-Ni).	ferryl iron	42-47	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	229-233
28738658-1	2017	In this work, an ultrasensitive chemiluminescence (CL) aptasensor was prepared for thrombin detection based on iron porphyrin catalyzing luminol - hydrogen peroxide luminescence under alkaline conditions, and iron porphyrin was desorbed from chitosan modified magnetic oxide graphene composite (CS@Fe3O4@GO).	ferryl iron	298-303	coagulation factor II, thrombin	Homo sapiens	83-91
28738658-5	2017	Then, thrombin aptamer (T-Apt) and hemin (HM, an iron porphyrin) were sequentially modified on the surface of CS@Fe3O4@GO to form CS@Fe3O4@GO@T-Apt@HM.	ferryl iron	113-118	coagulation factor II, thrombin	Homo sapiens	6-14
28738658-5	2017	Then, thrombin aptamer (T-Apt) and hemin (HM, an iron porphyrin) were sequentially modified on the surface of CS@Fe3O4@GO to form CS@Fe3O4@GO@T-Apt@HM.	ferryl iron	133-138	coagulation factor II, thrombin	Homo sapiens	6-14
28738658-7	2017	When thrombin existed in solutions, HM was desorbed from the surface of CS@Fe3O4@GO@T-Apt@HM owing to the strong specific recognition ability between thrombin and T-Apt, causing the changes of CL signal.	ferryl iron	75-80	coagulation factor II, thrombin	Homo sapiens	5-13
28738658-7	2017	When thrombin existed in solutions, HM was desorbed from the surface of CS@Fe3O4@GO@T-Apt@HM owing to the strong specific recognition ability between thrombin and T-Apt, causing the changes of CL signal.	ferryl iron	75-80	coagulation factor II, thrombin	Homo sapiens	150-158
28738658-10	2017	Finally, the CS@Fe3O4@GO@T-Apt@HM-CL aptasensor was used for the determination of thrombin in practical serum samples and recoveries ranged from 95% to 103%.	ferryl iron	16-21	coagulation factor II, thrombin	Homo sapiens	82-90
28738658-11	2017	Those satisfactory results revealed potential application of the CS@Fe3O4@GO@T-Apt@HM-CL aptasensor for thrombin detection in monitoring and diagnosis of human blood diseases.	ferryl iron	68-73	coagulation factor II, thrombin	Homo sapiens	104-112
28711619-0	2017	Adsorption of Pb(II) ions from aqueous environment using eco-friendly chitosan schiff"s base@Fe3O4 (CSB@Fe3O4) as an adsorbent; kinetics, isotherm and thermodynamic studies.	ferryl iron	104-109	submaxillary gland androgen regulated protein 3B	Homo sapiens	14-20
28711619-2	2017	In this study a novel CSB@Fe3O4 was prepared, characterized by XRD, FTIR, SEM, TEM, and VSM analysis and utilized as an adsorbent material for the removal of Pb(II) ions from aqueous solution.	ferryl iron	26-31	submaxillary gland androgen regulated protein 3B	Homo sapiens	158-164
28783443-3	2017	The physic-chemical characterization of the Fe3O4/poly(MMA-b-NIPAAm-b-AAc) magnetic composite nanosphere was investigated by FTIR, HNMR spectroscopies and GPC, FESEM, XRD, VSM and DLS.	ferryl iron	44-49	glycine-N-acyltransferase	Homo sapiens	70-73
28783443-4	2017	The thermo-sensitivity of the Fe3O4/P(MMA-b-NIPAAm-b-AAc) magnetic composite nanosphere was confirmed via DLS at 40  C. DOX encapsulation efficiency was calculated to be 98.2%.	ferryl iron	30-35	glycine-N-acyltransferase	Homo sapiens	53-56
28887990-1	2017	In this study, differently coated superparamagnetic Fe3O4 (magnetite) nanoparticles were synthesized, characterized and used for lysozyme (Ly) and bovine serum albumin (BSA) adsorption.	ferryl iron	52-57	lysozyme	Homo sapiens	129-137
28887990-1	2017	In this study, differently coated superparamagnetic Fe3O4 (magnetite) nanoparticles were synthesized, characterized and used for lysozyme (Ly) and bovine serum albumin (BSA) adsorption.	ferryl iron	52-57	albumin	Homo sapiens	154-167
29117136-4	2017	Water-soluble magnetofluid with Fe3O4 nanoparticles incorporated in the inner aqueous core of CLC shells is responsible for the non-invasive transportable capability.	ferryl iron	32-37	Charcot-Leyden crystal galectin	Homo sapiens	94-97
28735184-6	2017	The maximum adsorption capacity of GO/Fe3O4-g-G3.0 for Pb(II) was 181.4mgg-1 at 298K.	ferryl iron	38-43	submaxillary gland androgen regulated protein 3B	Homo sapiens	55-61
29084287-1	2017	A method for grafting ethylenediamine to a magnetic graphene oxide composite (EDA-GO@Fe3O4) was developed for Cr(VI) decontamination.	ferryl iron	85-90	ectodysplasin A	Homo sapiens	78-81
29084287-2	2017	The physicochemical properties of EDA-GO@Fe3O4 were characterized using HRTEM, EDS, FT-IR, TG-DSC, and XPS.	ferryl iron	41-46	ectodysplasin A	Homo sapiens	34-37
29084287-5	2017	The pseudo-second-order model is suitable for being applied to fit the adsorption processes of Cr(VI) with GO@Fe3O4 and EDA-GO@Fe3O4.	ferryl iron	127-132	ectodysplasin A	Homo sapiens	120-123
29084287-11	2017	These results indicated that EDA-GO@Fe3O4 is a potential and suitable candidate for treatment of heavy metal wastewater.	ferryl iron	36-41	ectodysplasin A	Homo sapiens	29-32
28821044-4	2017	Owing to the strong metal chelating ability of chitosan, the Fe3O4/CS NPs exhibited better adsorption capacity and faster adsorption rates for Pb(II) and Cd(II) than those of pure Fe3O4.	ferryl iron	61-66	submaxillary gland androgen regulated protein 3B	Homo sapiens	143-149
28821044-5	2017	The maximum adsorption capacities of Fe3O4/CS NPs for Pb(II) and Cd(II) were 79.24 and 36.42mgg-1, respectively.	ferryl iron	37-42	submaxillary gland androgen regulated protein 3B	Homo sapiens	54-60
29168708-0	2017	Preparation of magnetic carbon/Fe3O4 supported zero-valent iron composites and their application in Pb(II) removal from aqueous solutions.	ferryl iron	31-36	submaxillary gland androgen regulated protein 3B	Homo sapiens	100-106
28976726-3	2017	Fe3O4@AMCA-MIL53(Al) nanocomposite was characterized by TGA, FTIR, SEM-EDX, XRD, HRTEM, BET, VSM (vibrating sample magnetometry), and XPS analyses.	ferryl iron	0-5	T-box transcription factor 1	Homo sapiens	56-59
28976726-3	2017	Fe3O4@AMCA-MIL53(Al) nanocomposite was characterized by TGA, FTIR, SEM-EDX, XRD, HRTEM, BET, VSM (vibrating sample magnetometry), and XPS analyses.	ferryl iron	0-5	delta/notch like EGF repeat containing	Homo sapiens	88-91
28544916-1	2017	A highly sensitive o-phenylenediamine (OPD) sensor based on a Fe3O4 doped with functionalized multi-walled carbon nanotubes (Fe3O4@f-MWCNTs) composite fabricated glassy carbon electrode (GCE) was developed.	ferryl iron	62-67	guanylate cyclase 2E, pseudogene	Homo sapiens	187-190
28544916-2	2017	The modified Fe3O4@f-MWCNTs/GCE showed an enhanced current (Ipa) response toward OPD relative to that of a Fe3O4/GCE, f-MWCNTs/GCE, and a bare GCE.	ferryl iron	13-18	guanylate cyclase 2E, pseudogene	Homo sapiens	28-31
28544916-2	2017	The modified Fe3O4@f-MWCNTs/GCE showed an enhanced current (Ipa) response toward OPD relative to that of a Fe3O4/GCE, f-MWCNTs/GCE, and a bare GCE.	ferryl iron	13-18	guanylate cyclase 2E, pseudogene	Homo sapiens	107-116
28544916-2	2017	The modified Fe3O4@f-MWCNTs/GCE showed an enhanced current (Ipa) response toward OPD relative to that of a Fe3O4/GCE, f-MWCNTs/GCE, and a bare GCE.	ferryl iron	13-18	guanylate cyclase 2E, pseudogene	Homo sapiens	113-116
28544916-2	2017	The modified Fe3O4@f-MWCNTs/GCE showed an enhanced current (Ipa) response toward OPD relative to that of a Fe3O4/GCE, f-MWCNTs/GCE, and a bare GCE.	ferryl iron	13-18	guanylate cyclase 2E, pseudogene	Homo sapiens	113-116
28544916-3	2017	Under optimum conditions, the Fe3O4@f-MWCNTs/GCE showed a wide linear range remove at OPD concentrations of 0.6-80microM.	ferryl iron	30-35	guanylate cyclase 2E, pseudogene	Homo sapiens	45-48
28925683-0	2017	3D Nanostructured Palladium-Functionalized Graphene-Aerogel-Supported Fe3O4 for Enhanced Ru(bpy)32+-Based Electrochemiluminescent Immunosensing of Prostate Specific Antigen.	ferryl iron	70-75	kallikrein related peptidase 3	Homo sapiens	147-172
32264225-6	2017	Based on the HPLC-Q-TOF/MS results, 29 hydrophobic peptides assigned to 12 proteins were clearly identified in 5 ng muL-1 human serum digestion upon treatment with Fe3O4@TbBd nanospheres, much better than those obtained without treatment, confirming the outstanding performance of the Fe3O4@TbBd nanospheres in proteome analysis.	ferryl iron	164-169	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	116-121
28753905-4	2017	Batch Cr(VI) adsorption performances of the resultant Fe3O4@Zr-CTS microspheres revealed that the maximum adsorption capacity of 280.97 mg/g were achieved under pH 4.0 at 298 K. The XPS analyses indicated that 61.1% of the adsorbed Cr(VI) was reduced to Cr(III) due to the oxidization of alcoholic groups on C-6 in CTS which served as electron donors to carbonyl groups.	ferryl iron	54-59	complement C6	Homo sapiens	308-311
28579461-0	2017	Covalently bonded pancreatic lipase onto the dithiocarbamate/chitosan-based magnetite: Stepwise fabrication of Fe3O4@CS/NHCS-Lip as a novel and promising nanobiocatalyst.	ferryl iron	111-116	pancreatic lipase	Homo sapiens	18-35
29031450-2	2017	The composite CoPz(S-Bu)8/SiO2@Fe3O4 appeared to be an active catalyst in the oxidation of benzyl alcohol in aqueous solution using hydrogen peroxide (H2O2) as oxidant under Xe-lamp irradiation, with 36.4% conversion of benzyl alcohol, about 99% selectivity for benzoic acid and turnover number (TON) of 61.7 at ambient temperature.	ferryl iron	31-36	COPI coat complex subunit zeta 1	Homo sapiens	14-18
29031450-3	2017	The biomimetic catalyst CoPz(S-Bu)8 was supported on the magnetic carrier SiO2@Fe3O4 so as to suspend it in aqueous solution to react with substrates, utilizing its lipophilicity.	ferryl iron	79-84	COPI coat complex subunit zeta 1	Homo sapiens	24-28
29031450-1	2017	A novel magnetically recoverable thioporphyrazine catalyst (CoPz(S-Bu)8/SiO2@Fe3O4) was prepared by immobilization of the cobalt octkis(butylthio) porphyrazine complex (CoPz(S-Bu)8) on silica-coated magnetic nanospheres (SiO2@Fe3O4).	ferryl iron	77-82	COPI coat complex subunit zeta 1	Homo sapiens	60-64
29031450-1	2017	A novel magnetically recoverable thioporphyrazine catalyst (CoPz(S-Bu)8/SiO2@Fe3O4) was prepared by immobilization of the cobalt octkis(butylthio) porphyrazine complex (CoPz(S-Bu)8) on silica-coated magnetic nanospheres (SiO2@Fe3O4).	ferryl iron	77-82	COPI coat complex subunit zeta 1	Homo sapiens	169-173
29031450-1	2017	A novel magnetically recoverable thioporphyrazine catalyst (CoPz(S-Bu)8/SiO2@Fe3O4) was prepared by immobilization of the cobalt octkis(butylthio) porphyrazine complex (CoPz(S-Bu)8) on silica-coated magnetic nanospheres (SiO2@Fe3O4).	ferryl iron	226-231	COPI coat complex subunit zeta 1	Homo sapiens	60-64
32264225-6	2017	Based on the HPLC-Q-TOF/MS results, 29 hydrophobic peptides assigned to 12 proteins were clearly identified in 5 ng muL-1 human serum digestion upon treatment with Fe3O4@TbBd nanospheres, much better than those obtained without treatment, confirming the outstanding performance of the Fe3O4@TbBd nanospheres in proteome analysis.	ferryl iron	285-290	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	116-121
28780139-2	2017	Magnetization of MIL-101-NMe3 were achieved concurrently by adding MIL-101-NMe3 and Fe3O4@SiO2 to the sample solution under ultrasonication.	ferryl iron	84-89	NME/NM23 nucleoside diphosphate kinase 3	Homo sapiens	25-29
28929355-0	2017	Post-treatment Method for the Synthesis of Monodisperse Binary FePt-Fe3O4 Nanoparticles.	ferryl iron	68-73	solute carrier family 35 member G1	Homo sapiens	0-4
28929355-3	2017	In this paper, a facile post-treatment method was applied to consume the excess iron, which was oxidized to Fe3O4 after post-treatment at 150 and 200  C, and a monodisperse binary FePt-Fe3O4 nanoparticle system was generated.	ferryl iron	108-113	solute carrier family 35 member G1	Homo sapiens	24-28
28929355-3	2017	In this paper, a facile post-treatment method was applied to consume the excess iron, which was oxidized to Fe3O4 after post-treatment at 150 and 200  C, and a monodisperse binary FePt-Fe3O4 nanoparticle system was generated.	ferryl iron	108-113	solute carrier family 35 member G1	Homo sapiens	120-124
28929355-3	2017	In this paper, a facile post-treatment method was applied to consume the excess iron, which was oxidized to Fe3O4 after post-treatment at 150 and 200  C, and a monodisperse binary FePt-Fe3O4 nanoparticle system was generated.	ferryl iron	185-190	solute carrier family 35 member G1	Homo sapiens	24-28
28929355-5	2017	However, the content and grain size of the fcc-Fe3O4 nanoparticles can be increased simply by increasing the post-treatment temperature from 150 to 200  C.	ferryl iron	47-52	solute carrier family 35 member G1	Homo sapiens	109-113
28845969-6	2017	Further economic evaluation finds that purification of every cubic meters of emulsion (water content: 10.00 mg mL-1) will cost about $34.18 for HH NWs, much lower than the $490.78 for the previously reported HH NPs, and $11 052.05-$23 420.32 Fe3O4 NP-based adsorbents, respectively.	ferryl iron	242-247	L1 cell adhesion molecule	Mus musculus	111-115
28780139-3	2017	The prepared Fe3O4@SiO2/MIL-101-NMe3 gave the adsorption capacity of 37.5mgg-1.	ferryl iron	13-18	NME/NM23 nucleoside diphosphate kinase 3	Homo sapiens	32-36
28842692-3	2017	Fe3O4-Fe nanohybrids-containing electrodes exhibited a high discharge capacity (13,890 mA h gc-1 at a current density of 500 mA gc-1), long cycle stability (100 cycles at a current rate of 500 mA gc-1 and fixed capacity regime of 1,000 mA h gc-1), and low overpotential (1.39 V at 40 cycles).	ferryl iron	0-5	solute carrier family 25 member 22	Homo sapiens	92-96
28869515-2	2017	The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-coated Fe3O4 labeled as Fe3O4-anti-AFP, and the target is AFP.	ferryl iron	99-104	alpha fetoprotein	Homo sapiens	39-56
28869515-2	2017	The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-coated Fe3O4 labeled as Fe3O4-anti-AFP, and the target is AFP.	ferryl iron	99-104	alpha fetoprotein	Homo sapiens	63-66
28869515-2	2017	The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-coated Fe3O4 labeled as Fe3O4-anti-AFP, and the target is AFP.	ferryl iron	116-121	alpha fetoprotein	Homo sapiens	39-56
28869515-2	2017	The example BMNP in this study is anti-alpha-fetoprotein (anti-AFP) conjugated onto dextran-coated Fe3O4 labeled as Fe3O4-anti-AFP, and the target is AFP.	ferryl iron	116-121	alpha fetoprotein	Homo sapiens	63-66
28499172-1	2017	Fluorescence quenching was used to study the potential interaction mechanism of Bovine serum albumin (BSA) with either hydrophilic ferroferric oxide (Fe3O4) nanoparticles (NPs) or hydrophobic Fe3O4 NPs.	ferryl iron	150-155	albumin	Homo sapiens	87-100
28842692-3	2017	Fe3O4-Fe nanohybrids-containing electrodes exhibited a high discharge capacity (13,890 mA h gc-1 at a current density of 500 mA gc-1), long cycle stability (100 cycles at a current rate of 500 mA gc-1 and fixed capacity regime of 1,000 mA h gc-1), and low overpotential (1.39 V at 40 cycles).	ferryl iron	0-5	solute carrier family 25 member 22	Homo sapiens	128-132
28842692-3	2017	Fe3O4-Fe nanohybrids-containing electrodes exhibited a high discharge capacity (13,890 mA h gc-1 at a current density of 500 mA gc-1), long cycle stability (100 cycles at a current rate of 500 mA gc-1 and fixed capacity regime of 1,000 mA h gc-1), and low overpotential (1.39 V at 40 cycles).	ferryl iron	0-5	solute carrier family 25 member 22	Homo sapiens	128-132
28842692-3	2017	Fe3O4-Fe nanohybrids-containing electrodes exhibited a high discharge capacity (13,890 mA h gc-1 at a current density of 500 mA gc-1), long cycle stability (100 cycles at a current rate of 500 mA gc-1 and fixed capacity regime of 1,000 mA h gc-1), and low overpotential (1.39 V at 40 cycles).	ferryl iron	0-5	solute carrier family 25 member 22	Homo sapiens	128-132
32264363-5	2017	In vitro, Fe3O4@TiO2@mTiO2-DOX/siRNA effectively silences beta-catenin gene, induces tumor cell apoptosis and consequently significantly enhances the cancer suppression effect of the synergistic therapeutic agent.	ferryl iron	10-15	catenin beta 1	Homo sapiens	58-70
28528134-4	2017	Herein I addressed this issue by describing the synthesis, and testing of, pH-responsive Fe3O4@SiO2(FITC)-BTN/QUR/DOX multifunctional nanoparticles.	ferryl iron	89-94	butyrophilin subfamily 1 member A1	Homo sapiens	106-109
28521986-1	2017	In this study glucose reinforced Fe3O4@cellulose glyconanoparticles (MGN) were prepared using epichlorohydrin and amino acid (lysine and arginine) as a linker.	ferryl iron	33-38	helt bHLH transcription factor	Homo sapiens	69-72
28528134-9	2017	Moreover, proapoptotic and antiproliferative studies showed that Fe3O4@SiO2(FITC)-BTN/QUR/DOX nanoparticles can promote apoptosis, inhibit tumor cell proliferation, and enhance the chemotherapeutic effects of DOX against multidrug resistance.	ferryl iron	65-70	butyrophilin subfamily 1 member A1	Homo sapiens	82-85
28603956-3	2017	In this work, Fe3O4 NPs were modified with Gd chelates via linking peptides to construct NP-substrate (Fe3O4-pep-Gd) conjugates for kinetic MMP-2 activity assessment in vitro at the cellular level and in vivo.	ferryl iron	14-19	matrix metallopeptidase 2	Homo sapiens	140-145
28501171-2	2017	The modified magnetic Fe3O4 nanoparticles (MNPs) with polydopamine (PDA) and human serum albumin (HSA) were prepared through a one step self-polymerization under mild condition.	ferryl iron	22-27	albumin	Homo sapiens	83-96
28501180-0	2017	Detection of Abeta oligomers based on magnetic-field-assisted separation of aptamer-functionalized Fe3O4 magnetic nanoparticles and BaYF5:Yb,Er nanoparticles as upconversion fluorescence labels.	ferryl iron	99-104	amyloid beta precursor protein	Homo sapiens	13-18
28501180-1	2017	A sensitive and stable bioassay for the detection of Abeta oligomer (Abetao), a potentially promising candidate biomarker for Alzheimer"s disease (AD) diagnosis, was developed using Fe3O4 magnetic nanoparticles (MNPs) as the recognition and concentration elements and BaYF5:Yb,Er upconversion nanoparticles (UCNPs) as highly sensitive labels, conjugated with the Abetao aptamer (DNA1) and the complementary oligonucleotide of the Abetao aptamer (DNA2), respectively.	ferryl iron	182-187	amyloid beta precursor protein	Homo sapiens	53-58
28749447-5	2017	The internalization of the Fe3O4 NPs in Caco-2 cells was mediated by clathrin-related routes in both the control and an interleukin-1beta (IL-1beta)-induced inflammatory condition.	ferryl iron	27-32	interleukin 1 beta	Homo sapiens	120-137
28749447-5	2017	The internalization of the Fe3O4 NPs in Caco-2 cells was mediated by clathrin-related routes in both the control and an interleukin-1beta (IL-1beta)-induced inflammatory condition.	ferryl iron	27-32	interleukin 1 beta	Homo sapiens	139-147
28603956-3	2017	In this work, Fe3O4 NPs were modified with Gd chelates via linking peptides to construct NP-substrate (Fe3O4-pep-Gd) conjugates for kinetic MMP-2 activity assessment in vitro at the cellular level and in vivo.	ferryl iron	103-108	matrix metallopeptidase 2	Homo sapiens	140-145
28603956-6	2017	Benefiting from signal amplification through binding multiple Gd chelates to one linking peptide, Fe3O4-pep-Gd conjugates exhibited high sensitivity for the detection of MMP-2 (as low as 0.5 nM).	ferryl iron	98-103	matrix metallopeptidase 2	Homo sapiens	170-175
28603956-8	2017	Fe3O4-pep-Gd conjugates could also probe MMP-2 at cellular level and in vivo that indicates a great promise in in vitro diagnosis (IVD) and disease monitoring.	ferryl iron	0-5	matrix metallopeptidase 2	Homo sapiens	41-46
28435266-0	2017	EGFR-targeted delivery of DOX-loaded Fe3O4@ polydopamine multifunctional nanocomposites for MRI and antitumor chemo-photothermal therapy.	ferryl iron	37-42	epidermal growth factor receptor	Homo sapiens	0-4
28516279-3	2017	In this paper, for the first time, the preparation, characterization, and sorption capability of Fe3O4-graphitized carbon black (mGCB) composite toward some compounds of environmental interest were investigated.	ferryl iron	97-102	natriuretic peptide receptor 2	Mus musculus	129-133
28516279-4	2017	The synthesized mGCB consisted of micrometric GCB particles with 55 m2 g-1 surface area bearing some carbonyl and hydroxyl functionalities and the surface partially decorated by Fe3O4 microparticles.	ferryl iron	178-183	natriuretic peptide receptor 2	Mus musculus	16-20
28157658-0	2017	Macroporous graphene capped Fe3O4 for amplified electrochemiluminescence immunosensing of carcinoembryonic antigen detection based on CeO2@TiO2.	ferryl iron	28-33	CEA cell adhesion molecule 3	Homo sapiens	90-114
28284130-0	2017	Adsorption of Cd(II) and Pb(II) by in situ oxidized Fe3O4 membrane grafted on 316L porous stainless steel filter tube and its potential application for drinking water treatment.	ferryl iron	52-57	submaxillary gland androgen regulated protein 3B	Homo sapiens	14-31
28284130-3	2017	Here we report the performances of the in situ oxidized Fe3O4 membranes for removing two toxic cations Cd(II) and Pb(II) commonly existing in water and their potential applications for drinking water purification.	ferryl iron	56-61	submaxillary gland androgen regulated protein 3B	Homo sapiens	103-120
28284130-7	2017	XRD and FT-IR analyses indicated that the chemisorption might be the insertion of Cd(II) and Pb(II) into the Fe3O4 crystal faces of 311 and 511 to form mononuclear or binuclear coordination with O atoms of Fe-O6 groups.	ferryl iron	109-114	submaxillary gland androgen regulated protein 3B	Homo sapiens	82-99
28569510-2	2017	Herein, an ultrasensitive ECL biosensor for the detection of Cyclin-D1 (CCND1) was designed by utilizing in situ electrogenerated silver nanoclusters (AgNCs) as ECL emitters and Fe3O4-CeO2 nanocomposites as a coreaction accelerator.	ferryl iron	178-183	cyclin D1	Homo sapiens	61-70
28569510-2	2017	Herein, an ultrasensitive ECL biosensor for the detection of Cyclin-D1 (CCND1) was designed by utilizing in situ electrogenerated silver nanoclusters (AgNCs) as ECL emitters and Fe3O4-CeO2 nanocomposites as a coreaction accelerator.	ferryl iron	178-183	cyclin D1	Homo sapiens	72-77
28391839-2	2017	In this work, ionic liquid functionalized Fe3O4 nanoparticles were prepared via a simple two-step modification process and were used as substrate to immobilize bovine serum albumin (BSA).	ferryl iron	42-47	albumin	Homo sapiens	167-180
28056439-2	2017	This paramagnetic Fe3O4@GO composite (1microm size range) was decorated with antibodies against prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA), and then used to first capture these biomarkers and then deliver them to an 8-sensor detection chamber of a microfluidic immunoarray.	ferryl iron	18-23	kallikrein related peptidase 3	Homo sapiens	96-121
28056439-2	2017	This paramagnetic Fe3O4@GO composite (1microm size range) was decorated with antibodies against prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA), and then used to first capture these biomarkers and then deliver them to an 8-sensor detection chamber of a microfluidic immunoarray.	ferryl iron	18-23	kallikrein related peptidase 3	Homo sapiens	123-126
28056439-2	2017	This paramagnetic Fe3O4@GO composite (1microm size range) was decorated with antibodies against prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA), and then used to first capture these biomarkers and then deliver them to an 8-sensor detection chamber of a microfluidic immunoarray.	ferryl iron	18-23	folate hydrolase 1	Homo sapiens	132-166
28056439-2	2017	This paramagnetic Fe3O4@GO composite (1microm size range) was decorated with antibodies against prostate specific antigen (PSA) and prostate specific membrane antigen (PSMA), and then used to first capture these biomarkers and then deliver them to an 8-sensor detection chamber of a microfluidic immunoarray.	ferryl iron	18-23	folate hydrolase 1	Homo sapiens	168-172
28056439-3	2017	Screen-printed carbon sensors coated with electrochemically reduced graphene oxide (ERGO) and a second set of antibodies selectively capture the biomarker-laden Fe3O4@GO particles, which subsequently catalyze hydrogen peroxide reduction to detect PSA and PSMA.	ferryl iron	161-166	kallikrein related peptidase 3	Homo sapiens	247-250
28056439-3	2017	Screen-printed carbon sensors coated with electrochemically reduced graphene oxide (ERGO) and a second set of antibodies selectively capture the biomarker-laden Fe3O4@GO particles, which subsequently catalyze hydrogen peroxide reduction to detect PSA and PSMA.	ferryl iron	161-166	folate hydrolase 1	Homo sapiens	255-259
28056439-6	2017	The LOD for PSA was 1000-fold better than the only previous report of PSA detection using Fe3O4.	ferryl iron	90-95	kallikrein related peptidase 3	Homo sapiens	12-15
28056439-6	2017	The LOD for PSA was 1000-fold better than the only previous report of PSA detection using Fe3O4.	ferryl iron	90-95	kallikrein related peptidase 3	Homo sapiens	70-73
28092815-4	2017	Especially, Fe3O4/Cu nanocomposite shows superior cycling stability with the excellent reversible capacity of 664.0 and 512.6mAhg-1 retained over 500 cycles at the current densities of 300 and 1000mAg-1, respectively.	ferryl iron	12-17	dentin matrix protein 1	Mus musculus	197-202
28192992-4	2017	Briefly, we adsorb five different proteins (beta-casein, alpha-lactalbumin, human serum albumin, fibrinogen, and avidin) onto the surface of Fe3O4.	ferryl iron	141-146	lactalbumin alpha	Homo sapiens	57-74
28435266-6	2017	Meanwhile, the EGFR-targeted Fe3O4@PDA-PEG-EGFR-DOX NPs significantly inhibited the growth of tumors, showing a prominent in vivo synergistic antitumor effect.	ferryl iron	29-34	epidermal growth factor receptor	Homo sapiens	15-19
28435266-6	2017	Meanwhile, the EGFR-targeted Fe3O4@PDA-PEG-EGFR-DOX NPs significantly inhibited the growth of tumors, showing a prominent in vivo synergistic antitumor effect.	ferryl iron	29-34	epidermal growth factor receptor	Homo sapiens	43-47
30970815-2	2017	The Fe3O4@PDA/Hyp NSs were characterized by FTIR, TEM, DLS, and BET methods, respectively.	ferryl iron	4-9	delta/notch like EGF repeat containing	Homo sapiens	64-67
28435266-2	2017	This study developed epidermal growth factor receptor (EGFR) antibody-directed polydopamine-coated Fe3O4 nanoparticles (Fe3O4@PDA NPs) for magnetic resonance imaging and antitumor chemo-photothermal therapy.	ferryl iron	99-104	epidermal growth factor receptor	Homo sapiens	21-53
28435266-2	2017	This study developed epidermal growth factor receptor (EGFR) antibody-directed polydopamine-coated Fe3O4 nanoparticles (Fe3O4@PDA NPs) for magnetic resonance imaging and antitumor chemo-photothermal therapy.	ferryl iron	99-104	epidermal growth factor receptor	Homo sapiens	55-59
28435266-2	2017	This study developed epidermal growth factor receptor (EGFR) antibody-directed polydopamine-coated Fe3O4 nanoparticles (Fe3O4@PDA NPs) for magnetic resonance imaging and antitumor chemo-photothermal therapy.	ferryl iron	120-125	epidermal growth factor receptor	Homo sapiens	21-53
27870961-5	2017	The so prepared nanocarriers (Fe3O4@PCA-PEG-FA) were characterized by X-ray diffraction, TEM, TGA, FT-IR, DLS and VSM techniques.	ferryl iron	30-35	T-box transcription factor 1	Homo sapiens	94-97
28435266-2	2017	This study developed epidermal growth factor receptor (EGFR) antibody-directed polydopamine-coated Fe3O4 nanoparticles (Fe3O4@PDA NPs) for magnetic resonance imaging and antitumor chemo-photothermal therapy.	ferryl iron	120-125	epidermal growth factor receptor	Homo sapiens	55-59
28435266-3	2017	The synthesized Fe3O4@PDA-PEG-EGFR-DOX NPs revealed high storage capacity for doxorubicin (DOX) and high photothermal conversion efficiency.	ferryl iron	16-21	epidermal growth factor receptor	Homo sapiens	30-34
28435266-4	2017	The cell viability assay of Fe3O4@PDA-PEG-EGFR NPs indicated that Fe3O4@ PDA-PEG-EGFR NPs had no cell cytotoxicity.	ferryl iron	28-33	epidermal growth factor receptor	Homo sapiens	81-85
28435266-4	2017	The cell viability assay of Fe3O4@PDA-PEG-EGFR NPs indicated that Fe3O4@ PDA-PEG-EGFR NPs had no cell cytotoxicity.	ferryl iron	66-71	epidermal growth factor receptor	Homo sapiens	42-46
28435266-4	2017	The cell viability assay of Fe3O4@PDA-PEG-EGFR NPs indicated that Fe3O4@ PDA-PEG-EGFR NPs had no cell cytotoxicity.	ferryl iron	66-71	epidermal growth factor receptor	Homo sapiens	81-85
28435266-5	2017	However, Fe3O4@PDA-PEG-EGFR-DOX NPs could significantly decrease cell viability (~5% of remaining cell viability) because of both photothermal ablation and near-infrared light-triggered DOX release.	ferryl iron	9-14	epidermal growth factor receptor	Homo sapiens	23-27
28125220-0	2017	Chasing the Evasive Fe O Stretch and the Spin State of the Iron(IV)-Oxo Complexes by Photodissociation Spectroscopy.	ferryl iron	59-67	spindlin 1	Homo sapiens	41-45
28352173-3	2017	This magnetic NP (GPC@NIRF-Fe3O4) with superparamagnetic behavior showed high stability and safety in physiological conditions.	ferryl iron	27-32	glycophorin C (Gerbich blood group)	Homo sapiens	18-21
28352173-4	2017	In addition, GPC@NIRF-Fe3O4 achieved more specific uptake of human liver cancer cells than free Fe3O4 NPs.	ferryl iron	22-27	glycophorin C (Gerbich blood group)	Homo sapiens	13-16
28352173-4	2017	In addition, GPC@NIRF-Fe3O4 achieved more specific uptake of human liver cancer cells than free Fe3O4 NPs.	ferryl iron	96-101	glycophorin C (Gerbich blood group)	Homo sapiens	13-16
28352173-5	2017	Importantly, with superpara-magnetic iron oxide and strong NIR absorbance, GPC@NIRF-Fe3O4 NPs demonstrate prominent tumor-contrasted imaging performance both on fluorescent and T2-weighted magnetic resonance (MR) imaging modalities in a living body.	ferryl iron	84-89	glycophorin C (Gerbich blood group)	Homo sapiens	75-78
28352173-6	2017	The relative MR signal enhancement of GPC@NIRF-Fe3O4 NPs achieved 5.4-fold improvement compared with NIR-Fe3O4 NPs.	ferryl iron	47-52	glycophorin C (Gerbich blood group)	Homo sapiens	38-41
28352173-6	2017	The relative MR signal enhancement of GPC@NIRF-Fe3O4 NPs achieved 5.4-fold improvement compared with NIR-Fe3O4 NPs.	ferryl iron	105-110	glycophorin C (Gerbich blood group)	Homo sapiens	38-41
28352173-7	2017	Therefore, GPC@ NIRF-Fe3O4 NPs may be potentially used as a candidate for dual-modal imaging of tumors with information covalidated and directly compared by combining fluorescence and MR imaging.	ferryl iron	21-26	glycophorin C (Gerbich blood group)	Homo sapiens	11-14
28262673-4	2017	During the roasting process, part of Fe3+ in Fe3O4 was reduced to Fe2+ by gaseous SnO, and meanwhile Sn2+ was oxidized to Sn4+ and entered into Fe3-xSnxO4.	ferryl iron	45-50	strawberry notch homolog 1	Homo sapiens	82-85
28118570-1	2017	A novel conductive polymeric ionic liquid (IL)-Fe3O4 nanocomposite (represented as PIL-Fe3O4) based on inorganic-organic hybrid material was synthesized using two different methods.	ferryl iron	47-52	serpin family A member 2 (gene/pseudogene)	Homo sapiens	83-86
28118570-1	2017	A novel conductive polymeric ionic liquid (IL)-Fe3O4 nanocomposite (represented as PIL-Fe3O4) based on inorganic-organic hybrid material was synthesized using two different methods.	ferryl iron	87-92	serpin family A member 2 (gene/pseudogene)	Homo sapiens	83-86
28118570-2	2017	Nuclear magnetic resonance, Fourier transform infrared, X-ray diffraction, and field emission scanning electron microscopy characterized the structures of IL, Fe3O4 nanoparticles, and PIL-Fe3O4.	ferryl iron	188-193	serpin family A member 2 (gene/pseudogene)	Homo sapiens	184-187
27149164-5	2016	Sandwich immune complexes formed in the presence of the target biomarker carcinoembryonic antigen (CEA), and this formation induced the plasmonic coupling between the Au@Ag NRs and Fe3O4@Ag MNPs.	ferryl iron	181-186	CEA cell adhesion molecule 3	Homo sapiens	73-97
28202922-5	2017	Adsorption of AgNPs over Fe3O4@PDA was confirmed by TEM, FT-IR, XRD, TGA and magnetic property.	ferryl iron	25-30	T-box transcription factor 1	Homo sapiens	69-72
32263592-3	2017	In this study, Fe3O4/carboxymethylated chitosan/poly(3-acrylaminophenylboronic acid) (Fe3O4/CMCS/PAAPBA) nanospheres with enhanced properties are prepared by a facile and economical method, and possess excellent morphology, uniform size (~300 nm), high saturation magnetization (59 emu g-1), and high magnetic content (79%).	ferryl iron	15-20	G protein signaling modulator 2	Homo sapiens	92-96
27646502-2	2016	In this study, iron oxide nanoparticles-loaded bovine serum albumin (BSA) (Fe3O4/BSA) particles were prepared, which showed a spherical morphology with a diameter below 200 nm, negatively charged surface, and tunable magnetic property.	ferryl iron	75-80	albumin	Homo sapiens	54-67
27646502-7	2016	In this study, iron oxide nanoparticles-loaded bovine serum albumin (BSA) (Fe3O4/BSA) particles with a diameter below 200nm, negatively charged surface, tunable Fe3O4 content and subsequently adjustable magnetic property were prepared.	ferryl iron	75-80	albumin	Homo sapiens	54-67
27956150-4	2017	Glucose oxidase (GOx) was immobilized on the PVA-Fe3O4 nanocomposite via physical adsorption.	ferryl iron	49-54	hydroxyacid oxidase 1	Homo sapiens	0-15
27956150-4	2017	Glucose oxidase (GOx) was immobilized on the PVA-Fe3O4 nanocomposite via physical adsorption.	ferryl iron	49-54	hydroxyacid oxidase 1	Homo sapiens	17-20
27956150-9	2017	Presence of Fe3O4 nanoparticles in the PVA matrix enhanced the electron transfer between enzyme and electrode surface and the immobilized GOx showed excellent catalytic characteristic toward glucose.	ferryl iron	12-17	hydroxyacid oxidase 1	Homo sapiens	138-141
27956150-10	2017	The GOx/PVA-Fe3O4/Sn bioelectrode could measure glucose in the range from 5 x 10-3 to 30 mM with a sensitivity of 9.36 muA mM-1 and exhibited a lower detection limit of 8 muM at a signal-to-noise ratio of 3.	ferryl iron	12-17	hydroxyacid oxidase 1	Homo sapiens	4-7
32263592-4	2017	Due to the introduction of PAAPBA, the Fe3O4/CMCS/PAAPBA nanospheres have been developed as a pH-responsive strategy to reversibly capture and release glycoproteins with high selectivity and recyclability in a pure protein, a model protein mixture and even a biological sample.	ferryl iron	39-44	G protein signaling modulator 2	Homo sapiens	45-49
32263592-5	2017	Additionally, the Fe3O4/CMCS/PAAPBA nanospheres retained high separation efficiency (~94%) in a pure protein system after being recycled five times, showing the great potential of the boronate functionalized, pH-stimuli-responsive, magnetic nanospheres in the biomedical field.	ferryl iron	18-23	G protein signaling modulator 2	Homo sapiens	24-28
27906685-3	2017	The chimera constructed by VEGF RNA aptamer and Notch3 siRNA was bonded with heterogeneous Au-Fe3O4 nanoparticles by electrostatic interaction.	ferryl iron	94-99	vascular endothelial growth factor A	Homo sapiens	27-31
27906685-3	2017	The chimera constructed by VEGF RNA aptamer and Notch3 siRNA was bonded with heterogeneous Au-Fe3O4 nanoparticles by electrostatic interaction.	ferryl iron	94-99	notch receptor 3	Homo sapiens	48-54
27788352-0	2017	MRI/optical dual-modality imaging of vulnerable atherosclerotic plaque with an osteopontin-targeted probe based on Fe3O4 nanoparticles.	ferryl iron	115-120	secreted phosphoprotein 1	Mus musculus	79-90
27772707-3	2017	The Lyz-imprinted Fe3O4/PMMA/PDOPA SSINs possessed average diameters of 200nm, high magnetic content, high saturation magnetization, as well as excellent specific recognition capacity toward Lyz template, exhibiting their great potential for biomacromolecular recognition.	ferryl iron	18-23	lysozyme	Homo sapiens	4-7
27772707-3	2017	The Lyz-imprinted Fe3O4/PMMA/PDOPA SSINs possessed average diameters of 200nm, high magnetic content, high saturation magnetization, as well as excellent specific recognition capacity toward Lyz template, exhibiting their great potential for biomacromolecular recognition.	ferryl iron	18-23	lysozyme	Homo sapiens	191-194
27693160-2	2017	Two types of Fe3O4-NPs were synthetized and characterized, being denominated NP1 and NP2.	ferryl iron	13-18	neuronal pentraxin 1	Homo sapiens	77-80
27693160-2	2017	Two types of Fe3O4-NPs were synthetized and characterized, being denominated NP1 and NP2.	ferryl iron	13-18	neuropilin 2	Homo sapiens	85-88
27519319-1	2017	A Coke supported Fe3O4 and Fe0 composite (Fe0/Fe3O4/Coke) was prepared for the first time with the aim of evaluating its ability to be used as heterogeneous catalyst for the Fenton degradation of p-Nitrophenol (p-NP).	ferryl iron	17-22	purine nucleoside phosphorylase	Homo sapiens	211-215
27519319-1	2017	A Coke supported Fe3O4 and Fe0 composite (Fe0/Fe3O4/Coke) was prepared for the first time with the aim of evaluating its ability to be used as heterogeneous catalyst for the Fenton degradation of p-Nitrophenol (p-NP).	ferryl iron	46-51	purine nucleoside phosphorylase	Homo sapiens	211-215
27519319-6	2017	The recyclability of Fe0/Fe3O4/Coke was also investigated after three successive runs, in which p-NP degradation performances showed a slight difference with the first oxidation cycle with an acceptable iron leaching.	ferryl iron	25-30	purine nucleoside phosphorylase	Homo sapiens	96-100
27773281-1	2017	Magnetite (Fe3O4 nanoparticles (NPs)) HKUST-1 metal organic framework (MOF) composite as a support was used for surface imprinting of gallic acid imprinted polymer (HKUST-1-MOF-Fe3O4-GA-MIP) using vinyltrimethoxysilane (VTMOS) as the cross-linker.	ferryl iron	11-16	lysine acetyltransferase 8	Homo sapiens	71-74
27773281-1	2017	Magnetite (Fe3O4 nanoparticles (NPs)) HKUST-1 metal organic framework (MOF) composite as a support was used for surface imprinting of gallic acid imprinted polymer (HKUST-1-MOF-Fe3O4-GA-MIP) using vinyltrimethoxysilane (VTMOS) as the cross-linker.	ferryl iron	11-16	lysine acetyltransferase 8	Homo sapiens	165-176
27773281-1	2017	Magnetite (Fe3O4 nanoparticles (NPs)) HKUST-1 metal organic framework (MOF) composite as a support was used for surface imprinting of gallic acid imprinted polymer (HKUST-1-MOF-Fe3O4-GA-MIP) using vinyltrimethoxysilane (VTMOS) as the cross-linker.	ferryl iron	177-182	lysine acetyltransferase 8	Homo sapiens	71-74
27773281-1	2017	Magnetite (Fe3O4 nanoparticles (NPs)) HKUST-1 metal organic framework (MOF) composite as a support was used for surface imprinting of gallic acid imprinted polymer (HKUST-1-MOF-Fe3O4-GA-MIP) using vinyltrimethoxysilane (VTMOS) as the cross-linker.	ferryl iron	177-182	lysine acetyltransferase 8	Homo sapiens	165-176
27374556-0	2016	Improvement of the stability and activity of immobilized trypsin on modified Fe3O4 magnetic nanoparticles for hydrolysis of bovine serum albumin and its application in the bovine milk.	ferryl iron	77-82	albumin	Bos taurus	131-144
27614195-1	2016	A novel magnetic carboxylated cellulose nanocrystal composite (CCN-Fe3O4) was prepared as an adsorbent for the adsorption of Pb(II) from aqueous solution.	ferryl iron	67-72	submaxillary gland androgen regulated protein 3B	Homo sapiens	125-131
27614195-4	2016	Pb(II) adsorption onto CCN-Fe3O4 reached equilibrium in 240min, and the maximum adsorption capacity of Pb(II) was 63.78mgg-1 at 298.2K.	ferryl iron	27-32	submaxillary gland androgen regulated protein 3B	Homo sapiens	0-6
26858161-0	2016	The Magnetorheological Finishing (MRF) of Potassium Dihydrogen Phosphate (KDP) Crystal with Fe3O4 Nanoparticles.	ferryl iron	92-97	WNK lysine deficient protein kinase 1	Homo sapiens	74-77
27102906-2	2016	Multi-functionalized magnetic nanoparticles, Fe3O4@SiO2-MPS-AM-DMC-AMPS, were facilely prepared via a one-pot in situ polymerization of three different functional monomers, AM, DMC, and AMPS, on a Fe3O4@SiO2-MPS core-shell structure.	ferryl iron	45-50	adenylosuccinate lyase	Homo sapiens	67-71
27149164-5	2016	Sandwich immune complexes formed in the presence of the target biomarker carcinoembryonic antigen (CEA), and this formation induced the plasmonic coupling between the Au@Ag NRs and Fe3O4@Ag MNPs.	ferryl iron	181-186	CEA cell adhesion molecule 3	Homo sapiens	99-102
32263495-2	2016	The iron oxide (Fe3O4) particles were stabilized with pluronic F127 and coupled with dopamine-terminated Y-shaped ligands (Tat peptide and transferrin) as a result of the noncovalent conjugation of dopamine (of Y-shaped ligands) and the iron oxide nanoparticles.	ferryl iron	16-21	tyrosine aminotransferase	Homo sapiens	123-126
27585675-4	2016	When Fe3O4 NPs were co-incubated with insulin, Fe3O4 NPs had no effect on the structural transformation into amyloid-like fibrils but had higher affinity toward insulin fibrils.	ferryl iron	5-10	insulin	Homo sapiens	38-45
27585675-4	2016	When Fe3O4 NPs were co-incubated with insulin, Fe3O4 NPs had no effect on the structural transformation into amyloid-like fibrils but had higher affinity toward insulin fibrils.	ferryl iron	47-52	insulin	Homo sapiens	38-45
27658969-0	2016	Enhancing the Spin-Orbit Coupling in Fe3O4 Epitaxial Thin Films by Interface Engineering.	ferryl iron	37-42	spindlin 1	Homo sapiens	14-18
27658969-4	2016	Combined with the first-principle calculations, the results suggest that the bonding with Fe and Ga or As ions and the ionic distortion near the interface, as well as the FeO defects and oxygen vacancies, may increase the spin-orbit coupling in ultrathin Fe3O4 epitaxial films and in turn provide an enhanced damping.	ferryl iron	255-260	spindlin 1	Homo sapiens	222-226
28028501-3	2016	In this study, AS1411 aptamer was conjugated to Fe3O4@Au nanoparticles for specific targeting of mouse mammary carcinoma (4T1) cells that overexpress nucleolin.	ferryl iron	48-53	nucleolin	Mus musculus	150-159
26858161-5	2016	The surface texture as well as figure accuracy and PSD1 (power spectrum density) of potassium dihydrogen phosphate (KDP) is greatly improved after MRF, which clearly prove the feasibility of substituting CIP and abrasive with Fe3O4 in our novel MRF design.	ferryl iron	226-231	WNK lysine deficient protein kinase 1	Homo sapiens	116-119
32263495-2	2016	The iron oxide (Fe3O4) particles were stabilized with pluronic F127 and coupled with dopamine-terminated Y-shaped ligands (Tat peptide and transferrin) as a result of the noncovalent conjugation of dopamine (of Y-shaped ligands) and the iron oxide nanoparticles.	ferryl iron	16-21	transferrin	Homo sapiens	139-150
27581753-2	2016	In this study, a new type of nanoplatform (PDA@Fe3O4 + PES) was fabricated by using polydopamine (PDA, a photothermal conversion agent) to encapsulate Fe3O4 (a magnetic nanoparticle) and support 2-phenylethynesulfonamide (PES, an inhibitor of heat shock protein 70 (HSP70)).	ferryl iron	47-52	heat shock protein family A (Hsp70) member 4	Homo sapiens	243-264
27581753-2	2016	In this study, a new type of nanoplatform (PDA@Fe3O4 + PES) was fabricated by using polydopamine (PDA, a photothermal conversion agent) to encapsulate Fe3O4 (a magnetic nanoparticle) and support 2-phenylethynesulfonamide (PES, an inhibitor of heat shock protein 70 (HSP70)).	ferryl iron	47-52	heat shock protein family A (Hsp70) member 4	Homo sapiens	266-271
27581753-2	2016	In this study, a new type of nanoplatform (PDA@Fe3O4 + PES) was fabricated by using polydopamine (PDA, a photothermal conversion agent) to encapsulate Fe3O4 (a magnetic nanoparticle) and support 2-phenylethynesulfonamide (PES, an inhibitor of heat shock protein 70 (HSP70)).	ferryl iron	151-156	heat shock protein family A (Hsp70) member 4	Homo sapiens	243-264
27581753-2	2016	In this study, a new type of nanoplatform (PDA@Fe3O4 + PES) was fabricated by using polydopamine (PDA, a photothermal conversion agent) to encapsulate Fe3O4 (a magnetic nanoparticle) and support 2-phenylethynesulfonamide (PES, an inhibitor of heat shock protein 70 (HSP70)).	ferryl iron	151-156	heat shock protein family A (Hsp70) member 4	Homo sapiens	266-271
27660436-2	2016	Here, we employed magnetic Fe3O4 nanoparticles (MNP-Fe3O4) to improve the therapeutic effect of HHT and investigated its biological effects.	ferryl iron	27-32	modifier of Niemann Pick type C1	Mus musculus	48-51
27660436-2	2016	Here, we employed magnetic Fe3O4 nanoparticles (MNP-Fe3O4) to improve the therapeutic effect of HHT and investigated its biological effects.	ferryl iron	52-57	modifier of Niemann Pick type C1	Mus musculus	48-51
27660436-3	2016	Within a certain range of concentrations, the HHT-MNP-Fe3O4 showed a more enhanced inhibitory effect on the selected myeloid leukemia cell lines than HHT alone.	ferryl iron	54-59	modifier of Niemann Pick type C1	Mus musculus	50-53
27660436-4	2016	Compared with HHT, HHT-MNP-Fe3O4 could induce more extensive apoptosis in leukemia cells, which also showed more pronounced cell arrests at G0/G1 phase.	ferryl iron	27-32	modifier of Niemann Pick type C1	Mus musculus	23-26
27660436-5	2016	HHT-MNP-Fe3O4 enhanced antitumor activity by downregulating myeloid cell leukemia-1, which could inhibit the activation of caspase-3 and poly-ADP-ribose polymerase.	ferryl iron	8-13	modifier of Niemann Pick type C1	Mus musculus	4-7
27660436-5	2016	HHT-MNP-Fe3O4 enhanced antitumor activity by downregulating myeloid cell leukemia-1, which could inhibit the activation of caspase-3 and poly-ADP-ribose polymerase.	ferryl iron	8-13	caspase 3	Homo sapiens	123-132
27660436-5	2016	HHT-MNP-Fe3O4 enhanced antitumor activity by downregulating myeloid cell leukemia-1, which could inhibit the activation of caspase-3 and poly-ADP-ribose polymerase.	ferryl iron	8-13	poly(ADP-ribose) polymerase 1	Homo sapiens	137-163
27660436-6	2016	In vivo experiments using tumor-bearing animal models showed that the mean tumor volume with HHT-MNP-Fe3O4 was significantly smaller than that with HHT alone (193+-26 mm3 versus 457+-100 mm3, P&lt;0.05), while the mean weight was 0.67+-0.03 g versus 1.42+-0.56 g (P&lt;0.05).	ferryl iron	101-106	modifier of Niemann Pick type C1	Mus musculus	97-100
27660436-7	2016	Immunohistochemical study showed fewer myeloid cell leukemia-1-stained cells in mice treated with HHT-MNP-Fe3O4 than with the controls.	ferryl iron	106-111	modifier of Niemann Pick type C1	Mus musculus	102-105
27152972-1	2016	A novel magnetic mesoporous nanomicrospheres Fe3O4@SiO2@mTiO2 were synthetized and characterized by a series of techniques including FE-TEM, EDS, FE-SEM, PXRD, XPS, BET, TGA as well as VSM, and subsequently tested as a photocatalyst for the degradation of Acephate, Omethoate, and Methyl parathion under UV irradiation.	ferryl iron	45-50	delta/notch like EGF repeat containing	Homo sapiens	165-168
27152972-1	2016	A novel magnetic mesoporous nanomicrospheres Fe3O4@SiO2@mTiO2 were synthetized and characterized by a series of techniques including FE-TEM, EDS, FE-SEM, PXRD, XPS, BET, TGA as well as VSM, and subsequently tested as a photocatalyst for the degradation of Acephate, Omethoate, and Methyl parathion under UV irradiation.	ferryl iron	45-50	T-box transcription factor 1	Homo sapiens	170-173
27497721-3	2016	The morphological and magnetic properties of the Fe3O4-MIP beads were characterized by Transmission Electron Microscopy (TEM), Fourier Transform Infrared (FT-IR) Spectroscopy, Thermogravimetric Analysis (TGA), and Vibrating Sample Magnetometer (VSM).	ferryl iron	49-54	major intrinsic protein of lens fiber	Homo sapiens	55-58
27497721-4	2016	The characterization results suggested that MIP was synthesized evenly on Fe3O4-SiO2 surface.	ferryl iron	74-79	major intrinsic protein of lens fiber	Homo sapiens	44-47
26914374-5	2016	We functionalized the Fe3O4 nanoparticles with the gama-aminobutyrate type A receptor-associated proteins (GABARAP), which specifically interact with calreticulin (CRT).	ferryl iron	22-27	calreticulin	Homo sapiens	164-167
27343600-3	2016	The resultant P(MA-L-Phe-OMe)-functionalized magnetic nanoparticles (Fe3O4@P(MA-L-Phe-OMe)) were characterized by Fourier transform infrared (FT-IR) spectroscopy and elemental analysis.	ferryl iron	69-74	mal, T cell differentiation protein	Homo sapiens	16-20
27343600-3	2016	The resultant P(MA-L-Phe-OMe)-functionalized magnetic nanoparticles (Fe3O4@P(MA-L-Phe-OMe)) were characterized by Fourier transform infrared (FT-IR) spectroscopy and elemental analysis.	ferryl iron	69-74	mal, T cell differentiation protein	Homo sapiens	77-81
27343600-4	2016	The adsorption amount of Fe3O4@P(MA-L-Phe-OMe) nanoparticles to 2,4-D and 4-CPA were 39.82mgg(-1) and 29.02mgg(-1), respectively.	ferryl iron	25-30	mal, T cell differentiation protein	Homo sapiens	33-37
27343600-4	2016	The adsorption amount of Fe3O4@P(MA-L-Phe-OMe) nanoparticles to 2,4-D and 4-CPA were 39.82mgg(-1) and 29.02mgg(-1), respectively.	ferryl iron	25-30	carboxypeptidase A1	Homo sapiens	76-79
27343600-5	2016	Moreover, the prepared MSPE adsorbents showed good selectivity towards 2,4-D and 4-CPA due to the hydrophobic interactions and electrostatic forces between the target analytes and Fe3O4@P(MA-L-Phe-OMe).	ferryl iron	180-185	carboxypeptidase A1	Homo sapiens	83-86
27343600-5	2016	Moreover, the prepared MSPE adsorbents showed good selectivity towards 2,4-D and 4-CPA due to the hydrophobic interactions and electrostatic forces between the target analytes and Fe3O4@P(MA-L-Phe-OMe).	ferryl iron	180-185	mal, T cell differentiation protein	Homo sapiens	188-192
27343600-9	2016	Our work proved that the novel Fe3O4@P(MA-L-Phe-OMe) nanoparticles were the good adsorbents of magnetic solid phase extraction (MSPE) and have good potential for the analysis of trace compound in real samples.	ferryl iron	31-36	mal, T cell differentiation protein	Homo sapiens	39-43
27149399-3	2016	TPR analyses showed that the iron oxide present in the composites undergoes reduction at lower temperature to form Fe(2+) species present in Fe3O4, indicating that the iron oxide in the composite can exhibit greater reactivity in the catalytic processes compared to the original red mud.	ferryl iron	141-146	translocated promoter region, nuclear basket protein	Homo sapiens	0-3
27260448-4	2016	The Fe3O4@Au-Cys-FA electrode exhibits good electrocatalytic activity, and has good retention of chemisorbed SOx on the electrode because of its large surface area.	ferryl iron	4-9	sulfite oxidase	Homo sapiens	109-112
26914374-5	2016	We functionalized the Fe3O4 nanoparticles with the gama-aminobutyrate type A receptor-associated proteins (GABARAP), which specifically interact with calreticulin (CRT).	ferryl iron	22-27	calreticulin	Homo sapiens	150-162
29345887-0	2016	Nanotheranostic Based Iron Oxide (Fe3O4) Saturated Lactoferrin Nanocapsules for Colonic Adenocarcinoma.	ferryl iron	34-39	lactotransferrin	Mus musculus	51-62
29345887-3	2016	Novel multimodal multifunctional iron oxide (Fe3O4) saturated lactoferrin (FebLf) nanocapsules/nanocarriers (FebLf NCs) nanoformulation was fabricated.	ferryl iron	45-50	lactotransferrin	Mus musculus	62-73
27207044-3	2016	The novel synthesized TC4As-Fe3O4 nanoparticles were characterized by FTIR, XRD, TGA, VSM and SEM analysis.	ferryl iron	28-33	T-box transcription factor 1	Homo sapiens	81-84
27271347-1	2016	We report a facile approach to stabilize Fe3O4 nanoparticles (NPs) by using tetrathiafulvalene carboxylate (TTF-COO(-)) and to control electron transport with an enhanced magnetoresistance (MR) effect in TTF-COO-Fe3O4 NP assemblies.	ferryl iron	41-46	ras homolog family member H	Homo sapiens	108-111
27271347-1	2016	We report a facile approach to stabilize Fe3O4 nanoparticles (NPs) by using tetrathiafulvalene carboxylate (TTF-COO(-)) and to control electron transport with an enhanced magnetoresistance (MR) effect in TTF-COO-Fe3O4 NP assemblies.	ferryl iron	41-46	ras homolog family member H	Homo sapiens	204-207
27271347-1	2016	We report a facile approach to stabilize Fe3O4 nanoparticles (NPs) by using tetrathiafulvalene carboxylate (TTF-COO(-)) and to control electron transport with an enhanced magnetoresistance (MR) effect in TTF-COO-Fe3O4 NP assemblies.	ferryl iron	212-217	ras homolog family member H	Homo sapiens	108-111
27271347-2	2016	This TTF-COO-coating is advantageous over other conventional organic coatings, making it possible to develop stable Fe3O4 NP arrays for sensitive spintronics applications.	ferryl iron	116-121	ras homolog family member H	Homo sapiens	5-8
26830554-3	2016	The results showed that Rhodamine B was adsorbed rapidly on Fe3O4@SiO2@[OMIM]PF6 and was released using ethanol.	ferryl iron	60-65	sperm associated antigen 17	Homo sapiens	77-80
27101151-0	2016	Structural and Spectroscopic Characterization of a High-Spin {FeNO}(6) Complex with an Iron(IV)-NO(-) Electronic Structure.	ferryl iron	87-95	spindlin 1	Homo sapiens	56-60
27427586-4	2016	With BMP-2 as a model protein, this Fe3O4 nanopartilces-capped mesoporous silica showed a rapid response to the change of pH for protein delivery.	ferryl iron	36-41	bone morphogenetic protein 2	Homo sapiens	5-10
27427586-8	2016	These results show that Fe3O4 NPs-capped SBA-15 materials have an effective load for large molecule size proteins, such as BMP-2, and show an excellent applied prospect in pH-responsive controlled release system.	ferryl iron	24-29	bone morphogenetic protein 2	Homo sapiens	123-128
26686923-1	2016	A sandwich-type electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) by using ferroferric oxide@silica-amino groups (Fe3O4@SiO2-NH2) as carriers and gold nanoparticles-graphene oxide (GO-AuNPs) as platform.	ferryl iron	165-170	CEA cell adhesion molecule 3	Homo sapiens	86-110
27109197-2	2016	Then Fe3O4@SiO2@G@PIL was synthesized and used as modified QuEChERS adsorbent for the determination of preservatives in vegetables.	ferryl iron	5-10	serpin family A member 2 (gene/pseudogene)	Homo sapiens	18-21
27109197-3	2016	The size of about 200nm of Fe3O4 in Fe3O4@SiO2@G@PIL was selected as optimum size to clean-up.	ferryl iron	27-32	serpin family A member 2 (gene/pseudogene)	Homo sapiens	49-52
27109197-3	2016	The size of about 200nm of Fe3O4 in Fe3O4@SiO2@G@PIL was selected as optimum size to clean-up.	ferryl iron	36-41	serpin family A member 2 (gene/pseudogene)	Homo sapiens	49-52
26686923-0	2016	A sandwich-type electrochemical immunosensor for carcinoembryonic antigen based on signal amplification strategy of optimized ferrocene functionalized Fe3O4@SiO2 as labels.	ferryl iron	151-156	CEA cell adhesion molecule 3	Homo sapiens	49-73
26686923-1	2016	A sandwich-type electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) by using ferroferric oxide@silica-amino groups (Fe3O4@SiO2-NH2) as carriers and gold nanoparticles-graphene oxide (GO-AuNPs) as platform.	ferryl iron	165-170	CEA cell adhesion molecule 3	Homo sapiens	112-115
26686923-2	2016	The Fe3O4@SiO2-NH2 surface was used as linked reagents for co-immobilization of ferrocenecarboxylic acid (Fc-COOH) and secondary anti-CEA (Ab2) to prepare the signal probe, and it also could hasten the decomposition of hydrogen peroxide (H2O2) to amplify signals.	ferryl iron	4-9	CEA cell adhesion molecule 3	Homo sapiens	134-137
26749099-5	2016	Base on the superparamagnetic of Fe3O4@Ag NPs, target miRNA let-7b can be captured, concentrated and direct quantified within a PE tube without any PCR preamplification treatment.	ferryl iron	33-38	microRNA let-7b	Homo sapiens	60-66
27548967-2	2016	Fe3O4@ SiO2@ Al2O3  nH2O was characterized by XRD, TEM, VSM and BET nitrogen adsorption experiment.	ferryl iron	0-5	delta/notch like EGF repeat containing	Homo sapiens	64-67
25822331-4	2016	Fe3O4 magnetic nanoparticles (MNPs) and cisplatin were loaded onto the nanogel, by the swelling method and the conjugation of cisplatin with the -COOH group of MAA, respectively.	ferryl iron	0-5	MAA	Homo sapiens	160-163
26797949-7	2016	New magnetite (Fe3O4) produced by the redox reaction of NO3 (-) and Fe(0) was discovered on the surface of the Fe(0) obtained from L2.	ferryl iron	15-20	NBL1, DAN family BMP antagonist	Homo sapiens	56-59
26996194-5	2016	In this context, we reported the bottom-up synthesis of Fe3O4@SiO2(FITC)-FA/AICAR/DOX multifunctional nanoparticles aiming to neutralize survivin (BIRC5) to potentiate the efficacy of DOX against chemoresistance.	ferryl iron	56-61	baculoviral IAP repeat containing 5	Homo sapiens	147-152
26872327-0	2016	Nanosized yolk-shell Fe3O4@Zr(OH)x spheres for efficient removal of Pb(II) from aqueous solution.	ferryl iron	21-26	submaxillary gland androgen regulated protein 3B	Homo sapiens	68-74
26872327-1	2016	In this work, Fe3O4@Zr(OH)x yolk-shell nanospheres (YSNs) were synthesized via a two-step process and further examined as adsorbents for the removal of Pb(II).	ferryl iron	14-19	submaxillary gland androgen regulated protein 3B	Homo sapiens	152-158
26872327-3	2016	The adsorption results showed that Fe3O4@Zr(OH)x YSNs exhibited 41.6% higher Pb(II) adsorption capacity as compared to that of Fe3O4@SiO2@Zr(OH)x CSNs.	ferryl iron	35-40	submaxillary gland androgen regulated protein 3B	Homo sapiens	77-83
27031226-0	2016	Casp3/7-Instructed Intracellular Aggregation of Fe3O4 Nanoparticles Enhances T2 MR Imaging of Tumor Apoptosis.	ferryl iron	48-53	caspase 3	Homo sapiens	0-5
27031226-4	2016	In vitro results showed that Fe3O4@1 NPs could be subjected to caspase 3 (Casp3)-instructed aggregation.	ferryl iron	29-34	caspase 3	Homo sapiens	63-72
27031226-4	2016	In vitro results showed that Fe3O4@1 NPs could be subjected to caspase 3 (Casp3)-instructed aggregation.	ferryl iron	29-34	caspase 3	Homo sapiens	74-79
27031226-5	2016	T2 phantom MR imaging showed that the transverse molar relaxivity (r2) of Fe3O4@1 NPs with Casp3 or apoptotic HepG2 cells was significantly larger than those of control groups.	ferryl iron	74-79	caspase 3	Homo sapiens	91-96
26923221-3	2016	Water-dispersible Fe3O4 magnetic nanoparticles were incorporated in the inner aqueous phase by taking advantage of the immiscibility with the middle CLC oil phase.	ferryl iron	18-23	Charcot-Leyden crystal galectin	Homo sapiens	149-152
26562330-0	2016	Femtomolar level detection of RASSF1A tumor suppressor gene methylation by electrochemical nano-genosensor based on Fe3O4/TMC/Au nanocomposite and PT-modified electrode.	ferryl iron	116-121	Ras association domain family member 1	Homo sapiens	30-37
27046214-1	2016	In this work, ionic liquid modified Fe3O4@dopamine/graphene oxide/beta-cyclodextrin (ILs-Fe3O4@DA/GO/beta-CD) was used as supporting material to synthesize surface molecularly imprinted polymer (SMIP) which then was introduced into chemiluminescence (CL) to achieve an ultrasensitive and selective biosensor for determination of lysozyme (Lys).	ferryl iron	36-41	lysozyme	Homo sapiens	329-337
27046214-1	2016	In this work, ionic liquid modified Fe3O4@dopamine/graphene oxide/beta-cyclodextrin (ILs-Fe3O4@DA/GO/beta-CD) was used as supporting material to synthesize surface molecularly imprinted polymer (SMIP) which then was introduced into chemiluminescence (CL) to achieve an ultrasensitive and selective biosensor for determination of lysozyme (Lys).	ferryl iron	89-94	lysozyme	Homo sapiens	329-337
26995643-0	2016	Au nanoparticles grafted on Fe3O4 as effective SERS substrates for label-free detection of the 16 EPA priority polycyclic aromatic hydrocarbons.	ferryl iron	28-33	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	47-51
26995643-3	2016	Herein we report the synthesis and construction of Fe3O4@Au SERS substrate.	ferryl iron	51-56	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	60-64
26995643-7	2016	As a result of its remarkable sensitivity, the Fe3O4@Au-based SERS assay has been applied to detect the 16 EPA priority PAHs.	ferryl iron	47-52	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	62-66
26551223-2	2016	The M-GO was more effective to adsorb both As(III) and As(V) than M-rGO, because the more functional groups existing on the M-GO could lead to synthesize more Fe3O4 with M-GO.	ferryl iron	159-164	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	55-60
26250445-1	2016	Magnetic core/shell Fe3O4/Au nanoparticles were used in the determination of drug binding to bovine serum albumin (BSA) using a fluorescence spectroscopic method.	ferryl iron	20-25	albumin	Homo sapiens	100-113
26730414-1	2016	We report the synthesis, characterization and utilization of LAPONITE -stabilized magnetic iron oxide nanoparticles (LAP-Fe3O4 NPs) as a high performance contrast agent for in vivo magnetic resonance (MR) detection of tumors.	ferryl iron	121-126	LAP	Homo sapiens	61-64
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	15-20	LAP	Homo sapiens	90-93
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	15-20	LAP	Homo sapiens	119-122
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	123-128	LAP	Homo sapiens	90-93
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	123-128	LAP	Homo sapiens	119-122
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	123-128	LAP	Homo sapiens	90-93
26730414-2	2016	In this study, Fe3O4 NPs were synthesized by a facile controlled coprecipitation route in LAP solution, and the formed LAP-Fe3O4 NPs have great colloidal stability and about 2-fold increase of T2 relaxivity than Fe3O4 NPs (from 247.6 mM(-1) s(-1) to 475.9 mM(-1) s(-1)).	ferryl iron	123-128	LAP	Homo sapiens	119-122
26730414-3	2016	Moreover, cytotoxicity assay and cell morphology observation demonstrate that LAP-Fe3O4 NPs display good biocompatibility in the given Fe concentration range, and in vivo biodistribution results prove that NPs can be metabolized and cleared out of the body.	ferryl iron	82-87	LAP	Homo sapiens	78-81
26730414-5	2016	Therefore, the developed LAP-based Fe3O4 NPs with good colloidal stability and exceptionally high transverse relaxivity may have tremendous potential in MR imaging applications.	ferryl iron	35-40	LAP	Homo sapiens	25-28
26915683-1	2016	We developed a nanovector with double targeting properties for efficiently delivering the tumor suppressor gene RASSF1A specifically into hepatocellular carcinoma (HCC) cells by preparing galactosylated-carboxymethyl chitosan-magnetic iron oxide nanoparticles (Gal-CMCS-Fe3O4-NPs).	ferryl iron	270-275	Ras association (RalGDS/AF-6) domain family member 1	Mus musculus	112-119
26915683-2	2016	After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm.	ferryl iron	55-60	cerebral malaria susceptibility in CBA/N	Mus musculus	32-36
26915683-2	2016	After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm.	ferryl iron	55-60	cerebral malaria susceptibility in CBA/N	Mus musculus	87-91
26915683-2	2016	After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm.	ferryl iron	92-97	cerebral malaria susceptibility in CBA/N	Mus musculus	32-36
26915683-2	2016	After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm.	ferryl iron	92-97	cerebral malaria susceptibility in CBA/N	Mus musculus	87-91
26915683-3	2016	Gal-CMCS-Fe3O4-NPs had strong DNA condensing power in pH 7 solution and were largely nontoxic.	ferryl iron	9-14	cerebral malaria susceptibility in CBA/N	Mus musculus	4-8
26523294-2	2016	Initially, the transferrin receptor antibody (TfR Ab) functionalized Fe3O4@ZnO nanocomposites, followed by loading with doxorubicin (Dox) and denoted as Fe3O4@ZnO/Dox/TfR Ab, were prepared as an all-in-one system allowing for a targeted drug delivery with simultaneous concurrent chemoradiotherapy and magnetic resonance imaging (MRI) monitoring.	ferryl iron	69-74	transferrin receptor	Homo sapiens	15-35
26868035-0	2016	Preparation of Au-polydopamine functionalized carbon encapsulated Fe3O4 magnetic nanocomposites and their application for ultrasensitive detection of carcino-embryonic antigen.	ferryl iron	66-71	CEA cell adhesion molecule 3	Homo sapiens	150-175
26868035-5	2016	In this work, a highly label-free sensitive magnetic immunosensor was developed based on Au/PDA/Fe3O4@C@PGC nanocomposites for the detection of carcino-embryonic antigen (CEA).	ferryl iron	96-101	CEA cell adhesion molecule 3	Homo sapiens	144-169
26868035-5	2016	In this work, a highly label-free sensitive magnetic immunosensor was developed based on Au/PDA/Fe3O4@C@PGC nanocomposites for the detection of carcino-embryonic antigen (CEA).	ferryl iron	96-101	CEA cell adhesion molecule 3	Homo sapiens	171-174
26523294-2	2016	Initially, the transferrin receptor antibody (TfR Ab) functionalized Fe3O4@ZnO nanocomposites, followed by loading with doxorubicin (Dox) and denoted as Fe3O4@ZnO/Dox/TfR Ab, were prepared as an all-in-one system allowing for a targeted drug delivery with simultaneous concurrent chemoradiotherapy and magnetic resonance imaging (MRI) monitoring.	ferryl iron	153-158	transferrin receptor	Homo sapiens	15-35
32263123-4	2015	We show that the formed Fe3O4/Au-PEI-HA CNPs are colloidally stable, hemocompatible and cytocompatible in a given concentration range, and have a high affinity to target CD44 receptor-overexpressing cancer cells.	ferryl iron	24-29	CD44 molecule (Indian blood group)	Homo sapiens	170-174
26785603-0	2016	Multimodal iron oxide (Fe3O4)-saturated lactoferrin nanocapsules as nanotheranostics for real-time imaging and breast cancer therapy of claudin-low, triple-negative (ER(-)/PR(-)/HER2(-)).	ferryl iron	23-28	lactotransferrin	Mus musculus	40-51
26785603-0	2016	Multimodal iron oxide (Fe3O4)-saturated lactoferrin nanocapsules as nanotheranostics for real-time imaging and breast cancer therapy of claudin-low, triple-negative (ER(-)/PR(-)/HER2(-)).	ferryl iron	23-28	erb-b2 receptor tyrosine kinase 2	Mus musculus	178-182
26785603-1	2016	AIM: To unravel the multimodal nanotheranostic ability of Fe3O4-saturated bovine lactoferrin nanocapsules (FebLf NCs) in claudin-low, triple-negative breast cancer model.	ferryl iron	58-63	lactotransferrin	Mus musculus	81-92
26771508-6	2016	The prepared Her-Fe3O4@PLGA-PVP nanocomposites facilitate packing of anticancer drug (Tamoxifen) without premature release in the bloodstream, recognizing the target cells through binding of Herceptin antibody to HER2, a cell surface receptor expressed by breast cancer cells to promote HER2 receptor mediated endocytosis and finally releasing the drug at the intracellular site of tumor cells ("On" state) to induce apoptosis.	ferryl iron	17-22	erb-b2 receptor tyrosine kinase 2	Homo sapiens	213-217
26771508-6	2016	The prepared Her-Fe3O4@PLGA-PVP nanocomposites facilitate packing of anticancer drug (Tamoxifen) without premature release in the bloodstream, recognizing the target cells through binding of Herceptin antibody to HER2, a cell surface receptor expressed by breast cancer cells to promote HER2 receptor mediated endocytosis and finally releasing the drug at the intracellular site of tumor cells ("On" state) to induce apoptosis.	ferryl iron	17-22	erb-b2 receptor tyrosine kinase 2	Homo sapiens	287-291
26731200-2	2016	In the experiment, monodisperse Fe3O4@SiO2@Ag microspheres with hierarchical surface were developed and used as building block of SERS substrate, which not only realized fast capturing analyte through dispersion and collection under external magnet but also could be built into uniform film through magnetically induced self-assembly.	ferryl iron	32-37	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	130-134
32263123-5	2015	Due to the presence of Fe3O4 and Au components, the formed Fe3O4/Au-PEI-HA CNPs display a high r2 relaxivity (264.16 mM-1 s-1) and good X-ray attenuation property, rendering them with an ability to be used as a nanoprobe for targeted dual mode MR/CT imaging of CD44 receptor-overexpressing cancer cells in vitro and a xenografted tumor model in vivo.	ferryl iron	59-64	CD44 molecule (Indian blood group)	Homo sapiens	261-265
32263123-6	2015	The Fe3O4/Au-PEI-HA CNPs developed via this facile approach may hold great promise to be used as a unique platform for precision imaging of CD44 receptor-overexpressing tumors.	ferryl iron	4-9	CD44 molecule (Indian blood group)	Homo sapiens	140-144
26558409-3	2015	We presented here a novel magnetic separation-assistant fluorescence resonance energy transfer (MS-FRET) inhibition strategy for highly sensitive detection of nucleolin using Cy5.5-AS1411 as the donor and Fe3O4-polypyrrole core-shell (Fe3O4@PPY) nanoparticles as the NIR quenching acceptor.	ferryl iron	205-210	nucleolin	Homo sapiens	159-168
26558409-5	2015	Owing to the much stronger specific interaction of AS1411 and nucleolin, the presence of nucleolin could take Cy5.5-AS1411 apart from Fe3O4@PPY and restore the fluorescence of Cy5.5-AS1411.	ferryl iron	134-139	nucleolin	Homo sapiens	62-71
26558409-5	2015	Owing to the much stronger specific interaction of AS1411 and nucleolin, the presence of nucleolin could take Cy5.5-AS1411 apart from Fe3O4@PPY and restore the fluorescence of Cy5.5-AS1411.	ferryl iron	134-139	nucleolin	Homo sapiens	89-98
26558409-7	2015	Compared to nonseparation FRET inhibition, the separation of free Cy5.5-AS1411 from Cy5.5-AS1411-Fe3O4@PPY solution (the first magnetic separation, MS-1) had as high as 25-fold enhancement of the sensitivity, whereas further separation of the nucleolin-inducing far-between Fe3O4@PPY from the FRET inhibition solution (the second magnetic separation, MS-2) could further enhance the sensitivity to 35-fold.	ferryl iron	97-102	nucleolin	Homo sapiens	243-252
26462445-1	2015	A unique CdS/C@Fe3O4 nanoreactor was fabricated by the surface-imprinting technique, which effectively enhances the recyclability, stability, and selectivity for orientation recognition and photodegradation of ciprofloxacin in the binary mixed solution under visible-light irradiation.	ferryl iron	15-20	CDP-diacylglycerol synthase 1	Homo sapiens	9-12
26496966-0	2015	Core-Shell Ferromagnetic Nanorod Based on Amine Polymer Composite (Fe3O4@DAPF) for Fast Removal of Pb(II) from Aqueous Solutions.	ferryl iron	67-72	submaxillary gland androgen regulated protein 3B	Homo sapiens	99-105
26563827-1	2015	We report a strategy to coat Fe3O4 nanoparticles (NPs) with tetrathiafulvalene-fused carboxylic ligands (TTF-COO-) and to control electron conduction and magnetoresistance (MR) within the NP assemblies.	ferryl iron	29-34	ras homolog family member H	Homo sapiens	105-108
26563827-2	2015	The TTF-COO-Fe3O4 NPs were prepared by replacing oleylamine (OA) from OA-coated 5.7 nm Fe3O4 NPs.	ferryl iron	12-17	ras homolog family member H	Homo sapiens	4-7
26563827-2	2015	The TTF-COO-Fe3O4 NPs were prepared by replacing oleylamine (OA) from OA-coated 5.7 nm Fe3O4 NPs.	ferryl iron	87-92	ras homolog family member H	Homo sapiens	4-7
26563827-3	2015	In the TTF-COO-Fe3O4 NPs, the ligand binding density was controlled by the ligand size, and spin polarization on the Fe3O4 NPs was greatly improved.	ferryl iron	15-20	ras homolog family member H	Homo sapiens	7-10
26563827-3	2015	In the TTF-COO-Fe3O4 NPs, the ligand binding density was controlled by the ligand size, and spin polarization on the Fe3O4 NPs was greatly improved.	ferryl iron	15-20	spindlin 1	Homo sapiens	92-96
26563827-3	2015	In the TTF-COO-Fe3O4 NPs, the ligand binding density was controlled by the ligand size, and spin polarization on the Fe3O4 NPs was greatly improved.	ferryl iron	117-122	ras homolog family member H	Homo sapiens	7-10
26563827-3	2015	In the TTF-COO-Fe3O4 NPs, the ligand binding density was controlled by the ligand size, and spin polarization on the Fe3O4 NPs was greatly improved.	ferryl iron	117-122	spindlin 1	Homo sapiens	92-96
26563827-4	2015	As a result, the interparticle spacing within the TTF-COO-Fe3O4 NP assemblies are readily controlled by the geometric length of TTF-based ligand.	ferryl iron	58-63	ras homolog family member H	Homo sapiens	50-53
26563827-4	2015	As a result, the interparticle spacing within the TTF-COO-Fe3O4 NP assemblies are readily controlled by the geometric length of TTF-based ligand.	ferryl iron	58-63	ras homolog family member H	Homo sapiens	128-131
26563827-6	2015	The TTF-coating further stabilized the Fe3O4 NPs against deep oxidation and allowed I2-doping to increase electron conduction, making it possible to measure MR of the NP assembly at low temperature (&lt;100 K).	ferryl iron	39-44	ras homolog family member H	Homo sapiens	4-7
26563827-7	2015	The TTF-COO-coating provides a viable way for producing stable magnetic Fe3O4 NP assemblies with controlled electron transport and MR for spintronics applications.	ferryl iron	72-77	ras homolog family member H	Homo sapiens	4-7
26149480-0	2015	A comparative study for adsorption of lysozyme from aqueous samples onto Fe3O4 magnetic nanoparticles using different ionic liquids as modifier.	ferryl iron	73-78	lysozyme	Homo sapiens	38-46
26149480-1	2015	In this paper, nanoparticles of Fe3O4 as well as their modified forms with different ionic liquids (IL-Fe3O4) were prepared and used for adsorption of lysozyme.	ferryl iron	32-37	lysozyme	Homo sapiens	151-159
26149480-1	2015	In this paper, nanoparticles of Fe3O4 as well as their modified forms with different ionic liquids (IL-Fe3O4) were prepared and used for adsorption of lysozyme.	ferryl iron	103-108	lysozyme	Homo sapiens	151-159
26149480-6	2015	The maximum obtained adsorption capacities were 370.4, 400.0 500.0 and 526.3 mg of lysozyme for adsorption onto Fe3O4 and modified magnetic nanoparticles by [C4MIM][Br], [C6MIM][Br] and [C8MIM][Br] per gram of adsorbent, respectively.	ferryl iron	112-117	lysozyme	Homo sapiens	83-91
26149480-7	2015	The Langmuir adsorption constants were 0.004, 0.019, 0.024 and 0.012 L mg(-1) for adsorptions of lysozyme onto Fe3O4 and modified magnetic nanoparticles by [C4MIM][Br], [C6MIM][Br] and [C8MIM][Br], respectively.	ferryl iron	111-116	lysozyme	Homo sapiens	97-105
26318819-0	2015	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.	ferryl iron	31-36	lactotransferrin	Bos taurus	47-58
26318819-0	2015	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.	ferryl iron	31-36	epithelial cell adhesion molecule	Mus musculus	105-110
26318819-0	2015	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.	ferryl iron	31-36	prominin 1	Mus musculus	112-117
26318819-0	2015	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.	ferryl iron	31-36	CD44 antigen	Mus musculus	119-123
26708887-0	2015	Magnetic Nanoparticles of Fe3O4 Enhance Artesunate-inducing Apoptosis of SKM-1 Cells.	ferryl iron	26-31	sodium voltage-gated channel alpha subunit 4	Homo sapiens	73-78
26496966-3	2015	Here, we present novel Fe3O4@DAPF core-shell ferromagnetic nanorods (CSFMNRs) for the removal of Pb(II) from aqueous solutions; they were prepared by the facile surface modification of twin-like ferromagnetic Fe3O4 nanorods using a 2,3-diaminophenol and formaldehyde (DAPF)-based polymer.	ferryl iron	23-28	submaxillary gland androgen regulated protein 3B	Homo sapiens	97-103
26496966-3	2015	Here, we present novel Fe3O4@DAPF core-shell ferromagnetic nanorods (CSFMNRs) for the removal of Pb(II) from aqueous solutions; they were prepared by the facile surface modification of twin-like ferromagnetic Fe3O4 nanorods using a 2,3-diaminophenol and formaldehyde (DAPF)-based polymer.	ferryl iron	209-214	submaxillary gland androgen regulated protein 3B	Homo sapiens	97-103
26496966-6	2015	Pb(II) removal using the prepared Fe3O4@DAPF CSFMNRs was assessed, and comparable adsorption capacities (83.3 mg g(-1)) to the largest value were demonstrated.	ferryl iron	34-39	submaxillary gland androgen regulated protein 3B	Homo sapiens	0-6
26372171-1	2015	Fe3O4-TiO2 nanosheets (Fe3O4-TNS) were synthesized by means of lamellar reverse micelles and solvothermal method, which were characterized by TEM, XRD, XPS, BET, and magnetic property analysis.	ferryl iron	0-5	putative DNA recombination protein Bet	Escherichia coli	157-160
26356798-2	2015	In this report, scanning tunneling microscopy was used to study a Pt1-6/Fe3O4 model catalyst exposed to CO, H2, O2, and mixtures thereof at 550 K. CO extracts lattice oxygen atoms at the cluster perimeter to form CO2, creating large holes in the metal oxide surface.	ferryl iron	72-77	zinc finger protein 77	Homo sapiens	66-71
26001621-3	2015	The synthesized 3D Fe3O4-graphene macroscopic composites are characterized by SEM, XRD, XPS, BET, Raman and magnetic property and used as a versatile adsorbent for sub-ppm concentration of As(III) and As(V) removal from aqueous solutions.	ferryl iron	19-24	delta/notch like EGF repeat containing	Homo sapiens	93-96
26492983-1	2015	A pH- and temperature-responsive magnetic adsorbent [poly(N-isopropylacrylamide) grafted chitosan/Fe3O4 composite particles, CN-MCP], was synthesized for the removal of the endocrine-disrupting chemical nonylphenol.	ferryl iron	98-103	CD46 molecule	Homo sapiens	128-131
26522127-0	2015	Spin-dependent transport properties of Fe3O4/MoS2/Fe3O4 junctions.	ferryl iron	39-44	spindlin 1	Homo sapiens	0-4
26522127-0	2015	Spin-dependent transport properties of Fe3O4/MoS2/Fe3O4 junctions.	ferryl iron	50-55	spindlin 1	Homo sapiens	0-4
26522127-6	2015	Here, we show based on the first principle calculations that Fe3O4 keeps a nearly fully spin polarized electron band at the interface between MoS2 and Fe3O4.	ferryl iron	61-66	spindlin 1	Homo sapiens	88-92
26522127-6	2015	Here, we show based on the first principle calculations that Fe3O4 keeps a nearly fully spin polarized electron band at the interface between MoS2 and Fe3O4.	ferryl iron	151-156	spindlin 1	Homo sapiens	88-92
26507890-0	2015	Facile preparation of hyaluronic acid and transferrin co-modified Fe3O4 nanoparticles with inherent biocompatibility for dual-targeting magnetic resonance imaging of tumors in vivo.	ferryl iron	66-71	transferrin	Homo sapiens	42-53
26011415-5	2015	The decomposition efficiencies of PCB-209, PCB-167, PCB-153, and PCB-77 by Fe3O4 in an N2 atmosphere at 230  C were 88.5%, 82.5%, 69.9%, and 66.4%, respectively.	ferryl iron	75-80	pyruvate carboxylase	Homo sapiens	34-37
26011415-5	2015	The decomposition efficiencies of PCB-209, PCB-167, PCB-153, and PCB-77 by Fe3O4 in an N2 atmosphere at 230  C were 88.5%, 82.5%, 69.9%, and 66.4%, respectively.	ferryl iron	75-80	pyruvate carboxylase	Homo sapiens	43-46
26011415-5	2015	The decomposition efficiencies of PCB-209, PCB-167, PCB-153, and PCB-77 by Fe3O4 in an N2 atmosphere at 230  C were 88.5%, 82.5%, 69.9%, and 66.4%, respectively.	ferryl iron	75-80	pyruvate carboxylase	Homo sapiens	43-46
26011415-5	2015	The decomposition efficiencies of PCB-209, PCB-167, PCB-153, and PCB-77 by Fe3O4 in an N2 atmosphere at 230  C were 88.5%, 82.5%, 69.9%, and 66.4%, respectively.	ferryl iron	75-80	pyruvate carboxylase	Homo sapiens	43-46
26357471-3	2015	The resulting PEDOT-PIL-modified Fe3O4 hybrids were then explored as a sensing channel material for a chemiresistive sensor to detect VOC vapors.	ferryl iron	33-38	serpin family A member 2 (gene/pseudogene)	Homo sapiens	20-23
26222409-1	2015	In this paper, a multifunctional peptide-fluorescent-magnetic nanocomposites (Fe3O4@PEI@Cy5.5@PEG@HCBP-1 NPs) was synthesized via a layer-by-layer approach for potential application to cancer diagnoses.	ferryl iron	78-83	aminoacylase 3	Homo sapiens	98-104
25950936-0	2015	Electrochemiluminescence immunosensor based on multifunctional luminol-capped AuNPs@Fe3O4 nanocomposite for the detection of mucin-1.	ferryl iron	84-89	mucin 1, cell surface associated	Homo sapiens	125-132
25950936-1	2015	In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1).	ferryl iron	88-93	mucin 1, cell surface associated	Homo sapiens	269-276
25950936-1	2015	In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1).	ferryl iron	88-93	mucin 1, cell surface associated	Homo sapiens	278-282
25950936-1	2015	In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1).	ferryl iron	104-109	mucin 1, cell surface associated	Homo sapiens	269-276
25950936-1	2015	In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1).	ferryl iron	104-109	mucin 1, cell surface associated	Homo sapiens	278-282
27005163-0	2015	VCAM-1-targeted silica nanoparticles doped with FITC and Fe3O4 for dual-mode cellular imaging of LPS-induced inflammatory endothelial cells.	ferryl iron	57-62	vascular cell adhesion molecule 1	Homo sapiens	0-6
26101820-0	2015	Cyto/hemocompatible magnetic hybrid nanoparticles (Ag2S-Fe3O4) with luminescence in the near-infrared region as promising theranostic materials.	ferryl iron	56-61	angiotensin II receptor, type 1a	Mus musculus	51-55
26244448-0	2015	Corallite-like Magnetic Fe3O4@MnO2@Pt Nanocomposites as Multiple Signal Amplifiers for the Detection of Carcinoembryonic Antigen.	ferryl iron	24-29	CEA cell adhesion molecule 3	Homo sapiens	104-128
26244448-1	2015	A nonenzymatic sandwich-type electrochemical immunosensor using corallite-like magnetic Fe3O4@MnO2@Pt nanocomposites was developed for the sensitive detection of carcinoembryonic antigen (CEA).	ferryl iron	88-93	CEA cell adhesion molecule 3	Homo sapiens	162-186
26244448-1	2015	A nonenzymatic sandwich-type electrochemical immunosensor using corallite-like magnetic Fe3O4@MnO2@Pt nanocomposites was developed for the sensitive detection of carcinoembryonic antigen (CEA).	ferryl iron	88-93	CEA cell adhesion molecule 3	Homo sapiens	188-191
26357471-4	2015	The PEDOT-PIL-modified Fe3O4 sensor exhibited a tunable response, with high sensitivity (down to a concentration of 1 ppm) and low noise level, to VOCs; these VOCs include acetone vapor, which is present in the exhaled breath of potential lung cancer patients.	ferryl iron	23-28	serpin family A member 2 (gene/pseudogene)	Homo sapiens	10-13
26270967-2	2015	We measure the dynamic effective relaxation time taueff(t) and use scanning electron microscopy (SEM) and transmission electron microscopy (TEM) to investigate the C-reactive protein (CRP) as it associates with the BMN Fe3O4-antiCRP to form the magnetic cluster Fe3O4-antiCRP-CRP.	ferryl iron	219-224	C-reactive protein	Homo sapiens	164-182
26270967-2	2015	We measure the dynamic effective relaxation time taueff(t) and use scanning electron microscopy (SEM) and transmission electron microscopy (TEM) to investigate the C-reactive protein (CRP) as it associates with the BMN Fe3O4-antiCRP to form the magnetic cluster Fe3O4-antiCRP-CRP.	ferryl iron	219-224	C-reactive protein	Homo sapiens	184-187
26270967-5	2015	After the association, SEM and TEM images show that CRP and Fe3O4-antiCRP conjugate to form Fe3O4-antiCRP-CRP clusters hundreds of nanometers in size.	ferryl iron	60-65	C-reactive protein	Homo sapiens	70-73
26270967-5	2015	After the association, SEM and TEM images show that CRP and Fe3O4-antiCRP conjugate to form Fe3O4-antiCRP-CRP clusters hundreds of nanometers in size.	ferryl iron	92-97	C-reactive protein	Homo sapiens	52-55
26270967-5	2015	After the association, SEM and TEM images show that CRP and Fe3O4-antiCRP conjugate to form Fe3O4-antiCRP-CRP clusters hundreds of nanometers in size.	ferryl iron	92-97	C-reactive protein	Homo sapiens	70-73
25734221-1	2015	In this work, a facile one-pot strategy was proposed for the synthesis of C18-functionalized core-shell magnetic mesoporous silica composite (Fe3O4/mSiO2-C18).	ferryl iron	142-147	Bardet-Biedl syndrome 9	Homo sapiens	74-77
26170664-0	2015	Polyetherimide-grafted Fe3O4@SiO22 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging.	ferryl iron	23-28	vascular endothelial growth factor A	Homo sapiens	88-92
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	90-95	vascular endothelial growth factor A	Homo sapiens	141-145
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	90-95	vascular endothelial growth factor A	Homo sapiens	191-195
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	90-95	vascular endothelial growth factor A	Homo sapiens	191-195
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	176-181	vascular endothelial growth factor A	Homo sapiens	141-145
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	176-181	vascular endothelial growth factor A	Homo sapiens	191-195
26170664-2	2015	In this study, we designed a novel nanocarrier system of polyethyleneimine (PEI)-modified Fe3O4@SiO2, which allows high efficient loading of VEGF small hairpin (sh)RNA to form Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites for VEGF gene silencing as well as magnetic resonance (MR) imaging.	ferryl iron	176-181	vascular endothelial growth factor A	Homo sapiens	191-195
26170664-6	2015	The qualitative and quantitative analysis of cellular internalization into MCF-7 human breast cancer cells by Prussian blue staining and inductively coupled plasma atomic emission spectroscopy analysis, respectively, demonstrated that the Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites could be easily internalized by MCF-7 cells, and they exhibited significant inhibition of VEGF gene expression.	ferryl iron	239-244	vascular endothelial growth factor A	Homo sapiens	254-258
26170664-6	2015	The qualitative and quantitative analysis of cellular internalization into MCF-7 human breast cancer cells by Prussian blue staining and inductively coupled plasma atomic emission spectroscopy analysis, respectively, demonstrated that the Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites could be easily internalized by MCF-7 cells, and they exhibited significant inhibition of VEGF gene expression.	ferryl iron	239-244	vascular endothelial growth factor A	Homo sapiens	370-374
26170664-7	2015	Furthermore, the MR cellular images showed that the superparamagnetic iron oxide core of our Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites could also act as a T2-weighted contrast agent for cancer MR imaging.	ferryl iron	93-98	vascular endothelial growth factor A	Homo sapiens	108-112
26170664-8	2015	Our data highlight multifunctional Fe3O4@SiO2/PEI/VEGF shRNA nanocomposites as a potential platform for simultaneous gene delivery and MR cell imaging, which are promising as theranostic agents for cancer treatment and diagnosis in the future.	ferryl iron	35-40	vascular endothelial growth factor A	Homo sapiens	50-54
26092339-6	2015	Compared with Fe3O4@PD-Ti(4+) microspheres, the Fe3O4@PD-Nb(5+) microspheres exhibit superior selectivity to multi-phosphorylated peptides, and thus may be complementary to the conventional IMAC materials.	ferryl iron	48-53	C-C motif chemokine ligand 26	Homo sapiens	190-194
25943504-2	2015	A series of analytical techniques were employed for the characterization of the as-prepared restricted accessed Fe3O4@SiO2@PAR, and it was found that the as-prepared restricted accessed Fe3O4@SiO2@PAR nanoparticles have a porous structure with a BET surface area of around 99.4 m(2) g(-1), an average pore size of about 6.14 nm and a pore volume of 0.47 cm(3) g(-1).	ferryl iron	112-117	delta/notch like EGF repeat containing	Homo sapiens	246-249
25943504-2	2015	A series of analytical techniques were employed for the characterization of the as-prepared restricted accessed Fe3O4@SiO2@PAR, and it was found that the as-prepared restricted accessed Fe3O4@SiO2@PAR nanoparticles have a porous structure with a BET surface area of around 99.4 m(2) g(-1), an average pore size of about 6.14 nm and a pore volume of 0.47 cm(3) g(-1).	ferryl iron	186-191	delta/notch like EGF repeat containing	Homo sapiens	246-249
26217806-9	2015	Free amine groups of a small peptide, ACTH (4-11) were labeled by ester linked, NHS ester modified SiO2@Fe3O4 MNPs under physiological conditions.	ferryl iron	104-109	proopiomelanocortin	Homo sapiens	38-42
25734221-4	2015	Langmuir and Freundlich isothermal adsorption models can both be used to describe the adsorption process and the maximum Langmuir adsorption capacity of MB on Fe3O4/mSiO2-C18 at 25  C and pH 7.5 is 363.64 mg g(-1).	ferryl iron	159-164	Bardet-Biedl syndrome 9	Homo sapiens	171-174
25734221-2	2015	The Fe3O4/mSiO2-C18 composite, with an average size of 80 nm and a functionalized mesoporous silica shell of about 30 nm in thickness, has excellent adsorption ability toward methylene blue dye (MB) due to the large surface area (303 m(2) g(-1)) and the abundant hydrophobic C18 groups.	ferryl iron	4-9	Bardet-Biedl syndrome 9	Homo sapiens	16-19
25734221-2	2015	The Fe3O4/mSiO2-C18 composite, with an average size of 80 nm and a functionalized mesoporous silica shell of about 30 nm in thickness, has excellent adsorption ability toward methylene blue dye (MB) due to the large surface area (303 m(2) g(-1)) and the abundant hydrophobic C18 groups.	ferryl iron	4-9	Bardet-Biedl syndrome 9	Homo sapiens	275-278
26053888-3	2015	Spin dependent electrical transport is studied on Fe3O4/ZnS nanocomposites with different shell thickness, and a large magnetoresistance (MR) ratio is observed under the magnetic field of 1.0 T at room temperature and 100 K for the compacted sample by Fe3O4/ZnS nanocomposites, which is 50% larger than that of sample with pure Fe3O4 particles, indicating that the enhanced MR is contributed from the spin injection between Fe3O4 and ZnS layer.	ferryl iron	252-257	spindlin 1	Homo sapiens	0-4
32262392-1	2015	This work reports a facile synthesis of magnetic hybrids (Fe3O4-Au hybrids) with high SERS activity for detecting a low abundance of cancer cells.	ferryl iron	58-63	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	86-90
26053888-3	2015	Spin dependent electrical transport is studied on Fe3O4/ZnS nanocomposites with different shell thickness, and a large magnetoresistance (MR) ratio is observed under the magnetic field of 1.0 T at room temperature and 100 K for the compacted sample by Fe3O4/ZnS nanocomposites, which is 50% larger than that of sample with pure Fe3O4 particles, indicating that the enhanced MR is contributed from the spin injection between Fe3O4 and ZnS layer.	ferryl iron	252-257	spindlin 1	Homo sapiens	0-4
25901793-3	2015	An antibacterial assay indicated that the Fe3O4@SiO2-Ag nanospheres exhibited excellent antibacterial activities against Staphylococcus aureus and Escherichia coli, in which the minimum inhibition concentrations (MIC) were 40 mug mL(-1) and 20 mug mL(-1), respectively.	ferryl iron	42-47	L1 cell adhesion molecule	Mus musculus	230-243
26047337-1	2015	beta-Galactosidase was immobilized on chitosan-coated magnetic Fe3O4 nanoparticles and was used to produce galactooligosaccharides (GOS) from lactose.	ferryl iron	63-68	galactosidase beta 1	Homo sapiens	0-18
26415443-3	2015	The different concentrations of ethoprophos adsorbed on Fe3O4/Ag were analyzed by SERS and it was showed that the trace analysis of ethoprophos had been established, while the enhancement factor of probe molecules on Fe3O4/Ag was 1.	ferryl iron	56-61	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	82-86
25869528-0	2015	Rational synthesis of novel recyclable Fe3O4@MOF nanocomposites for enzymatic digestion.	ferryl iron	39-44	lysine acetyltransferase 8	Homo sapiens	45-48
25854197-7	2015	Benefitting from their excellent optical properties, their magnetic field and NIR light-responsive drug release capabilities and their enhanced photothermal effect, such nanostructured Fe3O4@PC-CDs-Au hybrid NPs are very promising for simultaneous imaging diagnostics and high efficacy therapy.	ferryl iron	185-190	NOC2 like nucleolar associated transcriptional repressor	Mus musculus	78-81
25848657-1	2015	A novel redox probe 3,4,9,10-perylenetetracarboxylic acid/o-phenylenediamine (PTCA/OPD) with well-defined redox peaks caused by the synergistic action between them was demonstrated via theoretical and practical research, and applied in an electrochemical aptasensor to detect thrombin (TB) based on an Fe3O4 magnetic bead (MB) as a nonenzymatic catalyst.	ferryl iron	302-307	coagulation factor II, thrombin	Homo sapiens	276-284
25848657-1	2015	A novel redox probe 3,4,9,10-perylenetetracarboxylic acid/o-phenylenediamine (PTCA/OPD) with well-defined redox peaks caused by the synergistic action between them was demonstrated via theoretical and practical research, and applied in an electrochemical aptasensor to detect thrombin (TB) based on an Fe3O4 magnetic bead (MB) as a nonenzymatic catalyst.	ferryl iron	302-307	coagulation factor II, thrombin	Homo sapiens	286-288
25691125-1	2015	A new type of bifunctional magnetic-fluorescent Fe3O4@SiO2-PDI-PAA/Ca(2+) nanoparticles has been prepared by coating PDI-cored star polymers (PDI-PAA) onto the surface of Fe3O4@SiO2 core-shell nanostructures.	ferryl iron	48-53	peptidyl arginine deiminase 1	Homo sapiens	59-62
23763576-7	2015	There were some disturbances to antioxidant enzymes after OC-Fe3O4 NPs treatment in the livers of animals 1 week post-exposure; with the most sensitive changes occurring in glutathione peroxidase (GPx) and glutathione S-transferase (GST) activities.	ferryl iron	61-66	hematopoietic prostaglandin D synthase	Rattus norvegicus	206-231
23763576-7	2015	There were some disturbances to antioxidant enzymes after OC-Fe3O4 NPs treatment in the livers of animals 1 week post-exposure; with the most sensitive changes occurring in glutathione peroxidase (GPx) and glutathione S-transferase (GST) activities.	ferryl iron	61-66	hematopoietic prostaglandin D synthase	Rattus norvegicus	233-236
26053888-0	2015	Investigation on Spin Dependent Transport Properties of Core-Shell Structural Fe3O4/ZnS Nanocomposites for Spintronic Application.	ferryl iron	78-83	spindlin 1	Homo sapiens	17-21
26053888-3	2015	Spin dependent electrical transport is studied on Fe3O4/ZnS nanocomposites with different shell thickness, and a large magnetoresistance (MR) ratio is observed under the magnetic field of 1.0 T at room temperature and 100 K for the compacted sample by Fe3O4/ZnS nanocomposites, which is 50% larger than that of sample with pure Fe3O4 particles, indicating that the enhanced MR is contributed from the spin injection between Fe3O4 and ZnS layer.	ferryl iron	50-55	spindlin 1	Homo sapiens	0-4
26053888-3	2015	Spin dependent electrical transport is studied on Fe3O4/ZnS nanocomposites with different shell thickness, and a large magnetoresistance (MR) ratio is observed under the magnetic field of 1.0 T at room temperature and 100 K for the compacted sample by Fe3O4/ZnS nanocomposites, which is 50% larger than that of sample with pure Fe3O4 particles, indicating that the enhanced MR is contributed from the spin injection between Fe3O4 and ZnS layer.	ferryl iron	252-257	spindlin 1	Homo sapiens	0-4
25691125-1	2015	A new type of bifunctional magnetic-fluorescent Fe3O4@SiO2-PDI-PAA/Ca(2+) nanoparticles has been prepared by coating PDI-cored star polymers (PDI-PAA) onto the surface of Fe3O4@SiO2 core-shell nanostructures.	ferryl iron	48-53	peptidyl arginine deiminase 1	Homo sapiens	117-120
25691125-1	2015	A new type of bifunctional magnetic-fluorescent Fe3O4@SiO2-PDI-PAA/Ca(2+) nanoparticles has been prepared by coating PDI-cored star polymers (PDI-PAA) onto the surface of Fe3O4@SiO2 core-shell nanostructures.	ferryl iron	48-53	peptidyl arginine deiminase 1	Homo sapiens	117-120
25691125-1	2015	A new type of bifunctional magnetic-fluorescent Fe3O4@SiO2-PDI-PAA/Ca(2+) nanoparticles has been prepared by coating PDI-cored star polymers (PDI-PAA) onto the surface of Fe3O4@SiO2 core-shell nanostructures.	ferryl iron	171-176	peptidyl arginine deiminase 1	Homo sapiens	59-62
25238184-2	2015	The results showed that linuron was adsorbed rapidly by Fe3O4@SiO2@[OMIM]PF6 and eluanted by ethanol.	ferryl iron	56-61	sperm associated antigen 17	Homo sapiens	73-76
25561279-0	2015	Attenuation of the early events of alpha-synuclein aggregation: a fluorescence correlation spectroscopy and laser scanning microscopy study in the presence of surface-coated Fe3O4 nanoparticles.	ferryl iron	174-179	synuclein alpha	Homo sapiens	35-50
25561279-3	2015	We studied the effect of Fe3O4 nanoparticle (NP) in the early stage of aggregation of A-syn using fluorescence correlation spectroscopy (FCS) and laser scanning microscopy.	ferryl iron	25-30	synuclein alpha	Homo sapiens	86-91
25561279-6	2015	In contrast, L-lysine (Lys)-coated Fe3O4 NPs showed strong binding with the monomeric A-syn, inhibiting the early events of aggregation.	ferryl iron	35-40	synuclein alpha	Homo sapiens	86-91
25662235-2	2015	In this work, a novel adsorbent, Fe3O4 incorporated polyacrylonitrile nanofiber mat (Fe-NFM), was successfully fabricated via electrospinning and solvothermal method, targeting to remove tetracycline (TC), a typical class of antibiotics, from aqueous solution.	ferryl iron	33-38	neurofilament medium chain	Homo sapiens	88-91
25662235-3	2015	Field emission scanning electron microscopy and X-ray diffraction spectroscopy were used to characterize the surface morphology and crystal structure of the Fe-NFM, and demonstrated that Fe-NFM was composed of continuous, randomly distributed uniform nanofibers with surface coating of Fe3O4 nanoparticles.	ferryl iron	286-291	neurofilament medium chain	Homo sapiens	190-193
25719273-0	2015	Synthesis, characterisation and analytical application of Fe3O4@SiO2@polyaminoquinoline magnetic nanocomposite for the extraction and pre-concentration of Cd(II) and Pb(II) in food samples.	ferryl iron	58-63	submaxillary gland androgen regulated protein 3B	Homo sapiens	155-172
25719273-1	2015	This work describes a novel Fe3O4@SiO2@polyaminoquinoline magnetic nanocomposite and its application in the pre-concentration of Cd(II) and Pb(II) ions.	ferryl iron	28-33	submaxillary gland androgen regulated protein 3B	Homo sapiens	129-146
25168935-6	2015	GLUT1 antibody conjugation can effectively target the injected Fe3O4 NPs to GLUT1-positive tumor cells in infantile hemangioma.	ferryl iron	63-68	solute carrier family 2 member 1	Homo sapiens	0-5
26328359-6	2015	TGA and VSM showed that the Fe3O4/P(MMA-AA) composite nanoparticles with a maximum saturation magnetization up to 45 emu g(-1) corresponding to the magnetite content of 78% exhibited superparamagntism.	ferryl iron	28-33	T-box transcription factor 1	Homo sapiens	0-3
25491985-1	2015	We constructed a novel core-shell structured Fe3O4@ZnO:Er(3+),Yb(3+)@(beta-CD) nanoparticles used as drug carrier to investigate the loading and controllable release properties of the chemotherapeutic drug etoposide (VP-16).	ferryl iron	45-50	host cell factor C1	Homo sapiens	217-222
25168935-6	2015	GLUT1 antibody conjugation can effectively target the injected Fe3O4 NPs to GLUT1-positive tumor cells in infantile hemangioma.	ferryl iron	63-68	solute carrier family 2 member 1	Homo sapiens	76-81
26100685-2	2015	We present the effect of functionalized magnetic core-shell nanoparticles of Fe3O4 (MNPs) with beta-cyclodextrin (beta-CD) on the aggregation/fibrillation of bovine serum albumin (BSA) under diabetic condition known as amyloidogenesis.	ferryl iron	77-82	albumin	Homo sapiens	165-178
25565814-3	2015	Both naked and modified Fe3O4 NPs induced LC3 lipidation and degraded p62, a monitor of autophagy flux.	ferryl iron	24-29	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	42-45
26606855-2	2015	METHODS &amp; RESULTS: A 22-nm MNP was first synthesized via magnetically coupling hard (FePt) and soft (Fe3O4) materials to produce high relative energy transfer.	ferryl iron	105-110	modifier of Niemann Pick type C1	Mus musculus	31-34
25565814-3	2015	Both naked and modified Fe3O4 NPs induced LC3 lipidation and degraded p62, a monitor of autophagy flux.	ferryl iron	24-29	nucleoporin 62	Homo sapiens	70-73
25565814-5	2015	Mechanistically, Fe3O4 NP-induced autophagy was accompanied by increased Beclin 1 and VPS34 and decreased Bcl-2, thus promoting the formation of the critical complex in autophagy initiation.	ferryl iron	17-22	beclin 1	Homo sapiens	73-81
25565814-5	2015	Mechanistically, Fe3O4 NP-induced autophagy was accompanied by increased Beclin 1 and VPS34 and decreased Bcl-2, thus promoting the formation of the critical complex in autophagy initiation.	ferryl iron	17-22	phosphatidylinositol 3-kinase catalytic subunit type 3	Homo sapiens	86-91
25565814-5	2015	Mechanistically, Fe3O4 NP-induced autophagy was accompanied by increased Beclin 1 and VPS34 and decreased Bcl-2, thus promoting the formation of the critical complex in autophagy initiation.	ferryl iron	17-22	BCL2 apoptosis regulator	Homo sapiens	106-111
25565814-7	2015	Therefore, this study suggested that Fe3O4 NPs can induce prosurvival autophagy in blood cells by modulating the Beclin l/Bcl-2/VPS34 complex.	ferryl iron	37-42	BCL2 apoptosis regulator	Homo sapiens	122-127
25565814-7	2015	Therefore, this study suggested that Fe3O4 NPs can induce prosurvival autophagy in blood cells by modulating the Beclin l/Bcl-2/VPS34 complex.	ferryl iron	37-42	phosphatidylinositol 3-kinase catalytic subunit type 3	Homo sapiens	128-133
25263922-6	2014	The Fe3O4@CD MNPs exhibit favorable removal performance toward Co(II) and 1-naphthol from the simulated effluent.	ferryl iron	4-9	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	63-69
25263922-3	2014	The removal performance of Fe3O4@CD MNPs toward Co(II) and 1-naphthol were investigated by using the batch technique.	ferryl iron	27-32	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	48-54
25263922-4	2014	The maximum sorption capacities of Fe3O4@CD MNPs toward Co(II) and 1-naphthol are higher than a series of adsorbent materials.	ferryl iron	35-40	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	56-62
25263922-5	2014	The simultaneous removal of Co(II) and 1-naphthol is achieved via the binding of Co(II) on the external surface sites of Fe3O4@CD MNPs and the incorporation of 1-naphthol into the hydrophobic cavity of surface-coated beta-CD.	ferryl iron	121-126	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	28-34
25263922-5	2014	The simultaneous removal of Co(II) and 1-naphthol is achieved via the binding of Co(II) on the external surface sites of Fe3O4@CD MNPs and the incorporation of 1-naphthol into the hydrophobic cavity of surface-coated beta-CD.	ferryl iron	121-126	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	81-87
25491795-3	2014	Protein cytochrome c was chosen as model target to evaluate the adsorptive property of Fe3O4/GO/CS.	ferryl iron	87-92	cytochrome c, somatic	Homo sapiens	8-20
25464095-2	2014	In the present study, we established a new screening assay based on magnetic Fe3O4@SiO2-COX-2 ligand fishing combination with high-performance liquid chromatography-diode array detector-mass spectrometry (HPLC-DAD-MSn) to screen and identify COX-2 inhibitors from green tea.	ferryl iron	77-82	prostaglandin-endoperoxide synthase 2	Homo sapiens	88-93
25464095-2	2014	In the present study, we established a new screening assay based on magnetic Fe3O4@SiO2-COX-2 ligand fishing combination with high-performance liquid chromatography-diode array detector-mass spectrometry (HPLC-DAD-MSn) to screen and identify COX-2 inhibitors from green tea.	ferryl iron	77-82	moesin	Homo sapiens	214-217
25464095-2	2014	In the present study, we established a new screening assay based on magnetic Fe3O4@SiO2-COX-2 ligand fishing combination with high-performance liquid chromatography-diode array detector-mass spectrometry (HPLC-DAD-MSn) to screen and identify COX-2 inhibitors from green tea.	ferryl iron	77-82	prostaglandin-endoperoxide synthase 2	Homo sapiens	242-247
25168935-0	2015	MRI molecular imaging using GLUT1 antibody-Fe3O4 nanoparticles in the hemangioma animal model for differentiating infantile hemangioma from vascular malformation.	ferryl iron	43-48	solute carrier family 2 member 1	Homo sapiens	28-33
25168935-1	2015	The purpose of this study is to evaluate the efficacy of glucose transporter protein 1 (GLUT1) antibody-conjugated iron oxide nanoparticles (Fe3O4 NPs) as magnetic resonance imaging (MRI) molecular imaging agents for differentiating infantile hemangioma from vascular malformation in the hemangioma animal model.	ferryl iron	141-146	solute carrier family 2 member 1	Homo sapiens	57-86
25168935-1	2015	The purpose of this study is to evaluate the efficacy of glucose transporter protein 1 (GLUT1) antibody-conjugated iron oxide nanoparticles (Fe3O4 NPs) as magnetic resonance imaging (MRI) molecular imaging agents for differentiating infantile hemangioma from vascular malformation in the hemangioma animal model.	ferryl iron	141-146	solute carrier family 2 member 1	Homo sapiens	88-93
25168935-2	2015	The conjugation of Fe3O4 NPs with anti-GLUT1 antibodies leads to a significantly increased uptake of NPs by human umbilical vein endothelial cells.	ferryl iron	19-24	solute carrier family 2 member 1	Homo sapiens	39-44
25168935-3	2015	MRI imaging following the intravenous injection of GLUT1 antibody-Fe3O4 NPs yielded a significantly lower signal intensity than did unconjugated Fe3O4 NPs.	ferryl iron	66-71	solute carrier family 2 member 1	Homo sapiens	51-56
25168935-4	2015	Upon histological examination of the GLUT1 antibody-Fe3O4 NPs, Prussian blue-stained NPs were identified in CD31-positive endothelial cells of hemangioma.	ferryl iron	52-57	solute carrier family 2 member 1	Homo sapiens	37-42
25543491-10	2014	Moreover, the active caspase-3 increased in SKM-1 cells after the exposure to MNPs-Fe3O4, while that was not in monocytes, and the increased expression of BCL-rambo and the decreased expression of survivin involved in the process were also observed.	ferryl iron	83-88	caspase 3	Homo sapiens	21-30
25543491-10	2014	Moreover, the active caspase-3 increased in SKM-1 cells after the exposure to MNPs-Fe3O4, while that was not in monocytes, and the increased expression of BCL-rambo and the decreased expression of survivin involved in the process were also observed.	ferryl iron	83-88	BCL2 like 13	Homo sapiens	155-164
24951924-1	2014	In this study, the TNT-imprinted polymer shell was created on nano-sized Fe3O4 cores in order to construct the nano-sized magnetic molecularly imprinted polymer (nano-MMIP).	ferryl iron	73-78	chromosome 16 open reading frame 82	Homo sapiens	19-22
32261895-3	2014	The core-shell magnetic epitope molecularly imprinted polymers (Fe3O4@EMIPs) exhibited a specific capture activity for the corresponding target protein, BSA.	ferryl iron	64-69	albumin	Bos taurus	153-156
32261895-5	2014	Moreover, the Fe3O4@EMIPs could separate BSA from the bovine blood sample.	ferryl iron	14-19	albumin	Bos taurus	41-44
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	alkaline phosphatase, placental	Homo sapiens	219-239
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	alkaline phosphatase, placental	Homo sapiens	241-244
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	RUNX family transcription factor 2	Homo sapiens	294-299
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	bone gamma-carboxyglutamate protein	Homo sapiens	301-304
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	integrin binding sialoprotein	Homo sapiens	306-309
32261896-4	2014	The incorporation of magnetic Fe3O4 nanoparticles into MBG/PCL scaffolds did not influence their apatite mineralization ability but endowed excellent magnetic heating ability and significantly stimulated proliferation, alkaline phosphatase (ALP) activity, osteogenesis-related gene expression (RUNX2, OCN, BSP, BMP-2 and Col-1) and extra-cellular matrix (ECM) mineralization of human bone marrow-derived mesenchymal stem cells (h-BMSCs).	ferryl iron	30-35	bone morphogenetic protein 2	Homo sapiens	311-316
25400232-2	2014	To address this issue, nanoparticles consisting of non-covalently coupled polyethyleneimine (PEI) and folic acid (FA) to the magnetic and fluorescent core/shell of Fe3O4@SiO2(FITC) was tested for their ability to deliver Notch-1 shRNA.	ferryl iron	164-169	notch receptor 1	Homo sapiens	221-228
25400232-3	2014	Our results showed that Fe3O4@SiO2(FITC)/PEI-FA/Notch-1 shRNA nanoparticles are 64 nm in diameter with well dispersed and superparamagnetic.	ferryl iron	24-29	notch receptor 1	Homo sapiens	48-55
25247461-6	2014	The analyses of the surface chemical composition of Fe3O4 by X-ray photoelectron spectroscopy (XPS) reveal that, upon the addition of NO2, the surface is oxidized and a contribution at 532.5 +- 0.4 eV in the O1s spectrum appears, showing that NO2 likely competes with toluene by dissociating on Fe(2+) sites and forming NO3(-).	ferryl iron	52-57	NBL1, DAN family BMP antagonist	Homo sapiens	320-323
25397920-2	2014	The biomarkers are the human C-reactive protein (CRP) while the BMNs are the anti-CRP bound onto dextran-coated Fe3O4 particles labeled as Fe3O4-antiCRP.	ferryl iron	112-117	C-reactive protein	Homo sapiens	82-85
25400232-5	2014	Magnetic resonance (MR) imaging and fluorescence microscopy showed significant preferential uptake of Fe3O4@SiO2(FITC)/PEI-FA/Notch-1 shRNA nanocomplex by MDA-MB-231 cells.	ferryl iron	102-107	notch receptor 1	Homo sapiens	126-133
25400232-7	2014	In light of the magnetic targeting capabilities of Fe3O4@SiO2(FITC)/PEI-FA, our results show that by complexing with a second molecular targeting therapeutic, such as Notch-1 shRNA in this report, Fe3O4@SiO2(FITC)/PEI-FA can be exploited as a novel, non-viral, and concurrent targeting delivery system for targeted gene therapy as well as for MR imaging in cancer diagnosis.	ferryl iron	51-56	notch receptor 1	Homo sapiens	167-174
25400232-7	2014	In light of the magnetic targeting capabilities of Fe3O4@SiO2(FITC)/PEI-FA, our results show that by complexing with a second molecular targeting therapeutic, such as Notch-1 shRNA in this report, Fe3O4@SiO2(FITC)/PEI-FA can be exploited as a novel, non-viral, and concurrent targeting delivery system for targeted gene therapy as well as for MR imaging in cancer diagnosis.	ferryl iron	197-202	notch receptor 1	Homo sapiens	167-174
25397920-2	2014	The biomarkers are the human C-reactive protein (CRP) while the BMNs are the anti-CRP bound onto dextran-coated Fe3O4 particles labeled as Fe3O4-antiCRP.	ferryl iron	139-144	C-reactive protein	Homo sapiens	82-85
25192200-3	2014	In this paper, we report the synthesis and structure of Fe3O4@SiO2@TiO2@Ag composite, which integrates SERS active Ag nanostructure with catalytically active titania.	ferryl iron	56-61	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	103-107
25192200-4	2014	The degradation of the typical dye molecule crystal violet (CV), as an example, is investigated in the presence of the as-prepared Fe3O4@SiO2@TiO2@Ag composite structure, which exhibits high catalytic activity and good SERS performance.	ferryl iron	131-136	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	219-223
25188029-0	2014	Gel-limited synthesis of dumbbell-like Fe3O4-Ag composite microspheres and their SERS applications.	ferryl iron	39-44	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	81-85
25188029-7	2014	When used as SERS substrates, the final dumbbell-like Fe3O4-Ag microspheres show fast magnetic separation and the selective detection of thiram for the surface capped oleic chain during the growth process.	ferryl iron	54-59	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	13-17
25288533-5	2014	The lyz-imprinted Fe3O4/PMMA/PDA MIPNSs exhibited specific recognition and efficient adsorption capacity toward lyz template.	ferryl iron	18-23	lysozyme	Homo sapiens	4-7
25329447-6	2014	We have demonstrated that Fe3O4@SiO2@Au nanoparticles can be utilized for two-photon luminescence (TPL) imaging, near-infrared surface-enhanced Raman scattering (NIR SERS) and cell collection by magnetic separation.	ferryl iron	26-31	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	166-170
25288533-5	2014	The lyz-imprinted Fe3O4/PMMA/PDA MIPNSs exhibited specific recognition and efficient adsorption capacity toward lyz template.	ferryl iron	18-23	lysozyme	Homo sapiens	112-115
25288533-6	2014	The amount of lyz adsorbed onto the lyz-imprinted Fe3O4/PMMA/PDA MIPNSs was about 4 times greater than that of the Fe3O4/PMMA/PDA non-imprinted polymer nanospheres (NIPNSs) and about 14, 5, and 5 times greater than that of BSA, BHb, and cyt C, respectively.	ferryl iron	50-55	lysozyme	Homo sapiens	14-17
25288533-6	2014	The amount of lyz adsorbed onto the lyz-imprinted Fe3O4/PMMA/PDA MIPNSs was about 4 times greater than that of the Fe3O4/PMMA/PDA non-imprinted polymer nanospheres (NIPNSs) and about 14, 5, and 5 times greater than that of BSA, BHb, and cyt C, respectively.	ferryl iron	50-55	lysozyme	Homo sapiens	36-39
25288533-6	2014	The amount of lyz adsorbed onto the lyz-imprinted Fe3O4/PMMA/PDA MIPNSs was about 4 times greater than that of the Fe3O4/PMMA/PDA non-imprinted polymer nanospheres (NIPNSs) and about 14, 5, and 5 times greater than that of BSA, BHb, and cyt C, respectively.	ferryl iron	115-120	lysozyme	Homo sapiens	14-17
25271644-1	2014	Fe3O4 (Fe3O4-CS) coated with magnetic chitosan was prepared as an adsorbent for the removal of Orange I from aqueous solutions and characterized by FTIR, XRD, SEM, TEM and TGA measurements.	ferryl iron	0-5	T-box transcription factor 1	Homo sapiens	172-175
25213260-0	2014	Preparation of C18-functionalized Fe3O4@SiO2 core-shell magnetic nanoparticles for extraction and determination of phthalic acid esters in Chinese herb preparations.	ferryl iron	34-39	Bardet-Biedl syndrome 9	Homo sapiens	15-18
25195850-5	2014	The electrochemical studies revealed that the Fe3O4/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe3O4 and rGO.	ferryl iron	46-51	guanylate cyclase 2E, pseudogene	Homo sapiens	56-59
25195850-5	2014	The electrochemical studies revealed that the Fe3O4/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe3O4 and rGO.	ferryl iron	166-171	guanylate cyclase 2E, pseudogene	Homo sapiens	56-59
25195850-6	2014	This implies that Fe3O4/rGO/GCE could exhibit excellent electrocatalytic activity and remarkable electron transfer kinetics towards the oxidation of DA.	ferryl iron	18-23	guanylate cyclase 2E, pseudogene	Homo sapiens	28-31
32261466-3	2014	Fe3O4@AuNP nanocomposites were used as labels of luminol, glucose oxidase (GOx) and signal aptamer which greatly enhanced the chemiluminescence emission and provided a simple magnetic separation approach to attain interference-free measurement for real detection.	ferryl iron	0-5	hydroxyacid oxidase 1	Homo sapiens	58-73
24981681-3	2014	Conversely, the reduction of Cr(VI) occurred only in the PRB for the EK/Fe3O4 PRB.	ferryl iron	72-77	RB transcriptional corepressor 1	Homo sapiens	57-60
24981681-5	2014	In addition, it was found that the majority of Cr(VI) migrating to the Fe3O4 PRB retained its oxidation state without being converted into Cr(III).	ferryl iron	71-76	RB transcriptional corepressor 1	Homo sapiens	77-80
24981681-6	2014	These two adverse effects were mitigated by maintaining the soil pH values at 6.8, but at the same time, 18% of Cr(VI) penetrated through the Fe3O4 PRB.	ferryl iron	142-147	RB transcriptional corepressor 1	Homo sapiens	148-151
24981681-7	2014	The penetration of Cr(VI) through the Fe3O4 PRB was successfully prevented by increasing the reaction time through the introduction of a cation exchange membrane between the Fe3O4 PRB and the anode well.	ferryl iron	38-43	RB transcriptional corepressor 1	Homo sapiens	44-47
24981681-7	2014	The penetration of Cr(VI) through the Fe3O4 PRB was successfully prevented by increasing the reaction time through the introduction of a cation exchange membrane between the Fe3O4 PRB and the anode well.	ferryl iron	38-43	RB transcriptional corepressor 1	Homo sapiens	180-183
24981681-7	2014	The penetration of Cr(VI) through the Fe3O4 PRB was successfully prevented by increasing the reaction time through the introduction of a cation exchange membrane between the Fe3O4 PRB and the anode well.	ferryl iron	174-179	RB transcriptional corepressor 1	Homo sapiens	44-47
24981681-7	2014	The penetration of Cr(VI) through the Fe3O4 PRB was successfully prevented by increasing the reaction time through the introduction of a cation exchange membrane between the Fe3O4 PRB and the anode well.	ferryl iron	174-179	RB transcriptional corepressor 1	Homo sapiens	180-183
24804549-0	2014	Biophysical interactions of polyamidoamine dendrimer coordinated Fe3O4 nanoparticles with insulin.	ferryl iron	65-70	insulin	Homo sapiens	90-97
24804549-2	2014	Here, we investigated the effect of surface chemistry of iron oxide (Fe3O4) nanoparticles on molecular interactions with human insulin by fluorescence, XRD and FTIR spectroscopy.	ferryl iron	69-74	insulin	Homo sapiens	127-134
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	30-35	insulin	Homo sapiens	96-103
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	30-35	insulin	Homo sapiens	157-164
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	63-68	insulin	Homo sapiens	96-103
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	63-68	insulin	Homo sapiens	157-164
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	63-68	insulin	Homo sapiens	96-103
24804549-4	2014	Our results demonstrate that, Fe3O4 and its conjugates such as Fe3O4-GSH, Fe3O4-GSH-G4 quenched insulin fluorescence, indicating strong interactions between insulin protein molecule and Fe3O4.	ferryl iron	63-68	insulin	Homo sapiens	157-164
24804549-6	2014	Both the Ksv and K (binding constant) values revealed that the interaction of Fe3O4 with insulin to be stronger over to dendrimer conjugates.	ferryl iron	78-83	insulin	Homo sapiens	89-96
24980686-6	2014	The prepared DAAO-PGMA-Fe3O4 nanoparticles exhibited excellent reusability and good stability.	ferryl iron	23-28	D-amino acid oxidase	Homo sapiens	13-17
32261550-4	2014	Excitingly, the experiments of the Fe3O4@C nanoparticles as drug carriers revealed an efficient drug-loading as high as 1.08 mg mg-1.	ferryl iron	35-40	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	128-132
24757954-0	2014	The C(RgdyK)-conjugated Fe3O4 nanoparticles with high drug load for dual-targeting integrin alpha(v)beta3-expressing cancer cells.	ferryl iron	24-29	integrin subunit alpha V	Homo sapiens	83-105
24757954-1	2014	A novel drug delivery system c(RGDyK)-modified Fe3O4 nanoparticles with high DOX load (R-DMP), which combines magnetic targeting, integrin alpha(v)beta3 targeting and high drug loading properties, was developed by chemical coupling both doxorubicin and peptide c(RGDyK) on the synthetic dual function magnetic nanoparticles (DMP) using a multi-hand cross-linker poly-L-glutamic acid.	ferryl iron	47-52	integrin subunit alpha V	Homo sapiens	130-152
32261466-3	2014	Fe3O4@AuNP nanocomposites were used as labels of luminol, glucose oxidase (GOx) and signal aptamer which greatly enhanced the chemiluminescence emission and provided a simple magnetic separation approach to attain interference-free measurement for real detection.	ferryl iron	0-5	hydroxyacid oxidase 1	Homo sapiens	75-78
24575420-1	2014	An ultrasound-assisted magnetic solid-phase extraction procedure with the [C7MIM][PF6] ionic liquid-coated Fe3O4-grafted graphene nanocomposite as the magnetic adsorbent has been developed for the determination of five nitrobenzene compounds (NBs) in environmental water samples, in combination with high performance liquid chromatography-photodiode array detector (HPLC-PDA).	ferryl iron	107-112	sperm associated antigen 17	Homo sapiens	82-85
24615010-4	2014	The resulting magnetic nanoparticles (denoted as Fe3O4@SiO2@GMA-NHNH2) demonstrated the high specificity of capturing glycopeptides from a tryptic digest of the sample comprising a standard non-glycosylated protein bovine serum albumin (BSA) and four standard glycoproteins with a weight ratio of 50 : 1, and the detection limit was as low as 130 fmol.	ferryl iron	49-54	albumin	Homo sapiens	222-235
24994954-0	2014	The synthesis and characterization of monodispersed chitosan-coated Fe3O4 nanoparticles via a facile one-step solvothermal process for adsorption of bovine serum albumin.	ferryl iron	68-73	albumin	Homo sapiens	156-169
24994954-6	2014	The adsorption properties of the CS-coated Fe3O4 NPs for bovine serum albumin (BSA) were investigated under different concentrations of BSA.	ferryl iron	43-48	albumin	Homo sapiens	64-77
24845203-5	2014	Following the cell biology mechanisms, we develop a liquid photo-immobilization approach to attach doxorubicin, folic acid, tumor necrosis factor-alpha, and interferon-gamma onto the oleic acid molecules coated Fe3O4 magnetic nanoparticles to prepare a kind of novel inner/outer controlled multi-target magnetic nanoparticle drug carrier.	ferryl iron	211-216	interferon gamma	Homo sapiens	157-173
24734871-3	2014	The MFNPs contain a well-defined core-shell structure of UCNP@Fe3O4@Au coated by poly(ethylene glycol) (PEG) and anti-HER2 antibody, displaying excellent dispersity in various aqueous solutions.	ferryl iron	62-67	erb-b2 receptor tyrosine kinase 2	Homo sapiens	118-122
24575420-3	2014	With the assistance of ultrasound, adsorbing nitrobenzene compounds by ionic liquid and self-aggregating ionic liquid onto the surface of the Fe3O4-grafted graphene proceeded synchronously, which made the extraction achieved the maximum within 20 min using only 144 muL [C7MIM][PF6] and 3 mg Fe3O4-grafted graphene.	ferryl iron	142-147	sperm associated antigen 17	Homo sapiens	278-281
24203562-6	2014	The as-prepared Fe3O4@Lyz-MIP nanoparticles with a mean diameter of 320 nm were coated with an MIP shell that was 20 nm thick, which enabled Fe3O4@Lyz-MIP to easily reach adsorption equilibrium.	ferryl iron	16-21	lysozyme	Homo sapiens	22-25
24280050-2	2014	First, 3-aminobenzeneboronic acid (APBA) was used as the functional monomer and cross-linking reagent, which was polymerized on the surface of silicate-coated magnetic iron oxide nanoparticles (Fe3O4@SiO2 NPs) in the presence of human immunoglobulin G (HIgG), as the template exhibiting the same Fc region but different Fab region to anti-HIV-1 after the addition of the initiator, ammonium persulfate.	ferryl iron	194-199	FA complementation group B	Homo sapiens	320-323
32261310-1	2014	A novel type of uniform magnetic imprinted nanomaterial for the recognition of bovine serum albumin (BSA) was prepared by anchoring MIP shells on the surface of silica deposited Fe3O4 NPs via a surface imprinting process and two-stage core-shell sol-gel polymerization.	ferryl iron	178-183	albumin	Bos taurus	86-99
24203562-6	2014	The as-prepared Fe3O4@Lyz-MIP nanoparticles with a mean diameter of 320 nm were coated with an MIP shell that was 20 nm thick, which enabled Fe3O4@Lyz-MIP to easily reach adsorption equilibrium.	ferryl iron	16-21	lysozyme	Homo sapiens	147-150
24203562-6	2014	The as-prepared Fe3O4@Lyz-MIP nanoparticles with a mean diameter of 320 nm were coated with an MIP shell that was 20 nm thick, which enabled Fe3O4@Lyz-MIP to easily reach adsorption equilibrium.	ferryl iron	141-146	lysozyme	Homo sapiens	22-25
24203562-6	2014	The as-prepared Fe3O4@Lyz-MIP nanoparticles with a mean diameter of 320 nm were coated with an MIP shell that was 20 nm thick, which enabled Fe3O4@Lyz-MIP to easily reach adsorption equilibrium.	ferryl iron	141-146	lysozyme	Homo sapiens	147-150
24203562-8	2014	Furthermore, Fe3O4@Lyz-MIP could selectively extract a target protein from real egg-white samples under an external magnetic field.	ferryl iron	13-18	lysozyme	Homo sapiens	19-22
24244939-0	2014	Rapid in situ identification of arsenic species using a portable Fe3O4@Ag SERS sensor.	ferryl iron	65-70	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	74-78
24184535-2	2014	SiO2@indol-IL can inhibit the proliferation of HepG-2 cells in 48 h. Fe3O4@indol-IL can mimic the function of catalase to disproportionate H2O2 to O2, and has obvious effect on the proliferation of HepG-2 cells in 72 h. Moreover, the two nanoparticles show some inhibition on the expression of hypoxia inducible factor (HIF-1alpha), glucose transporter (GLUT1) and the production of lactate in HepG-2 cells.	ferryl iron	69-74	catalase	Homo sapiens	110-118
24184535-2	2014	SiO2@indol-IL can inhibit the proliferation of HepG-2 cells in 48 h. Fe3O4@indol-IL can mimic the function of catalase to disproportionate H2O2 to O2, and has obvious effect on the proliferation of HepG-2 cells in 72 h. Moreover, the two nanoparticles show some inhibition on the expression of hypoxia inducible factor (HIF-1alpha), glucose transporter (GLUT1) and the production of lactate in HepG-2 cells.	ferryl iron	69-74	hypoxia inducible factor 1 subunit alpha	Homo sapiens	320-330
24184535-2	2014	SiO2@indol-IL can inhibit the proliferation of HepG-2 cells in 48 h. Fe3O4@indol-IL can mimic the function of catalase to disproportionate H2O2 to O2, and has obvious effect on the proliferation of HepG-2 cells in 72 h. Moreover, the two nanoparticles show some inhibition on the expression of hypoxia inducible factor (HIF-1alpha), glucose transporter (GLUT1) and the production of lactate in HepG-2 cells.	ferryl iron	69-74	solute carrier family 2 member 1	Homo sapiens	354-359
24244939-1	2014	Rapid and sensitive SERS identification and quantification of arsenic species in multiple matrices have been realized using a Fe3O4@Ag magnetic substrate.	ferryl iron	126-131	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	20-24
24244939-2	2014	The molecular structure of arsenic on Fe3O4@Ag characterized using EXAFS spectroscopy and DFT confirms the existence of a chemical effect on SERS enhancement.	ferryl iron	38-43	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	141-145
25109645-2	2014	The magnetic core of Fe3O4 was synthesized first by the sol-gel method, then protected by a layer of silica using tetraethylorthosilicate (TEOS) followed by functionalization using three aliphatic diamines: 1,2-ethanediamine (1,2-EDA), 1,5-pentanediamine (1,5-PDA) and 1,8-octanediamine (1,8-ODA).	ferryl iron	21-26	ectodysplasin A	Homo sapiens	230-233
28788450-1	2014	This research describes the preparation and sensor applications of multifunctional monodisperse, Fe3O4 nanoparticles-embedded poly(styrene)/poly(thiophene) (Fe3O4-PSt/PTh), core/shell nanoparticles.	ferryl iron	97-102	parathyroid hormone	Homo sapiens	167-170
28788450-2	2014	Monodisperse Fe3O4-PSt/PTh nanoparticles were prepared by free-radical combination (mini-emulsion/emulsion) polymerization for Fe3O4-PSt core and oxidative seeded emulsion polymerization for PTh shell in the presence of FeCl3/H2O2 as a redox catalyst, respectively.	ferryl iron	127-132	parathyroid hormone	Homo sapiens	23-26
28788450-3	2014	For applicability of Fe3O4-PSt/PTh as sensors, Fe3O4-PSt/PTh-immobilized poly(ethylene glycol) (PEG)-based hydrogels were fabricated by photolithography.	ferryl iron	47-52	parathyroid hormone	Homo sapiens	31-34
25109645-5	2014	The order of increasing metal capacity for copper ions using magnetic nano-adsorbents was Fe3O4-SiO2-1,2-EDA &lt; Fe3O4-SiO2-1,5-PDA &lt; Fe3O4-SiO2-1,8-ODA at 5 s equilibrium time.	ferryl iron	90-95	ectodysplasin A	Homo sapiens	105-108
25109645-5	2014	The order of increasing metal capacity for copper ions using magnetic nano-adsorbents was Fe3O4-SiO2-1,2-EDA &lt; Fe3O4-SiO2-1,5-PDA &lt; Fe3O4-SiO2-1,8-ODA at 5 s equilibrium time.	ferryl iron	114-119	ectodysplasin A	Homo sapiens	105-108
25109645-5	2014	The order of increasing metal capacity for copper ions using magnetic nano-adsorbents was Fe3O4-SiO2-1,2-EDA &lt; Fe3O4-SiO2-1,5-PDA &lt; Fe3O4-SiO2-1,8-ODA at 5 s equilibrium time.	ferryl iron	114-119	ectodysplasin A	Homo sapiens	105-108
24184619-1	2014	The interaction between ionic liquids modified magnetic Fe3O4 (Fe2) and bovine serum albumin (BSA) is reported and is compared with NH2 functionalized magnetic nanoparticles Fe3O4 (Fe1) based on the UV-visible spectrum, steady-state fluorescence measurements, synchronous fluorescence and DSC methods.	ferryl iron	56-61	albumin	Homo sapiens	79-92
24079826-2	2013	The small molecules (CS2), a NIR fluorescent chromophore, can be fixed into the covalently grafted polymer shell of the NPs by chemical reaction through a covalent bond to obtain stable CS2 dotted NPs Fe3O4@SiO2@PPEGMA-co-PGMA@CS2.	ferryl iron	201-206	chorionic somatomammotropin hormone 2	Homo sapiens	21-24
24090595-7	2013	For selective enrichment of phosphopeptides, the prepared Fe3O4@Ti-mSiO2 particles were applied for tryptic digests of beta-casein, mixtures of beta-casein and bovine serum albumin (BSA), and low-fat milk.	ferryl iron	58-63	albumin	Homo sapiens	167-180
23384700-2	2013	MATERIALS &amp; METHODS: The authors have functionalized Fe3O4 nanoparticles with 3-amino-propyltriethoxysilane (APTES) and conjugated it to yeast D-amino acid oxidase (DAAO) by coupling this with glutaraldehyde.	ferryl iron	57-62	D-amino acid oxidase	Homo sapiens	147-167
23384700-2	2013	MATERIALS &amp; METHODS: The authors have functionalized Fe3O4 nanoparticles with 3-amino-propyltriethoxysilane (APTES) and conjugated it to yeast D-amino acid oxidase (DAAO) by coupling this with glutaraldehyde.	ferryl iron	57-62	D-amino acid oxidase	Homo sapiens	169-173
23384700-6	2013	Fe3O4-APTES-DAAO was demonstrated to be more effective than free DAAO, confirming the validity of the system in cancer therapy.	ferryl iron	0-5	D-amino acid oxidase	Homo sapiens	12-16
23384700-6	2013	Fe3O4-APTES-DAAO was demonstrated to be more effective than free DAAO, confirming the validity of the system in cancer therapy.	ferryl iron	0-5	D-amino acid oxidase	Homo sapiens	65-69
23756150-3	2013	To that end, a multienzyme system including glutamate dehydrogenase (GluDH), glucose dehydrogenase (GDH) and cofactor NAD(H) were separately immobilized on silica coated Fe3O4 magnetic nanoparticles with an average diameter of 105 nm, and the effect of magnetic field strength and frequency on the kinetics of the coupled bi-enzyme reaction was investigated.	ferryl iron	170-175	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	77-98
23897214-5	2013	However, reactions carried out under similar conditions with MSO4 (M = Co and Fe) led to the isolation of two [M2(mu-Bz)2(mu-pyz)2(Bz)2] (HBz) isostructural infinite 1D ladder chains (M = Co (3) and M = Fe (4)).	ferryl iron	203-209	hemoglobin subunit zeta	Homo sapiens	138-141
24219664-0	2013	Epidermal growth factor receptor targeted nuclear delivery and high-resolution whole cell X-ray imaging of Fe3O4@TiO2 nanoparticles in cancer cells.	ferryl iron	107-112	epidermal growth factor receptor	Homo sapiens	0-32
24219664-2	2013	To allow for both cellular and subcellular nanoparticle delivery, we have created epidermal growth factor receptor (EGFR)-targeted Fe3O4@TiO2 nanoparticles that use the native intracellular trafficking of EGFR to improve internalization and nuclear translocation in EGFR-expressing HeLa cells.	ferryl iron	131-136	epidermal growth factor receptor	Homo sapiens	82-114
24219664-2	2013	To allow for both cellular and subcellular nanoparticle delivery, we have created epidermal growth factor receptor (EGFR)-targeted Fe3O4@TiO2 nanoparticles that use the native intracellular trafficking of EGFR to improve internalization and nuclear translocation in EGFR-expressing HeLa cells.	ferryl iron	131-136	epidermal growth factor receptor	Homo sapiens	116-120
24219664-2	2013	To allow for both cellular and subcellular nanoparticle delivery, we have created epidermal growth factor receptor (EGFR)-targeted Fe3O4@TiO2 nanoparticles that use the native intracellular trafficking of EGFR to improve internalization and nuclear translocation in EGFR-expressing HeLa cells.	ferryl iron	131-136	epidermal growth factor receptor	Homo sapiens	205-209
24219664-2	2013	To allow for both cellular and subcellular nanoparticle delivery, we have created epidermal growth factor receptor (EGFR)-targeted Fe3O4@TiO2 nanoparticles that use the native intracellular trafficking of EGFR to improve internalization and nuclear translocation in EGFR-expressing HeLa cells.	ferryl iron	131-136	epidermal growth factor receptor	Homo sapiens	205-209
23911770-0	2013	Magnetic Fe3O4@TiO2 nanoparticles-based test strip immunosensing device for rapid detection of phosphorylated butyrylcholinesterase.	ferryl iron	9-14	butyrylcholinesterase	Homo sapiens	110-131
23911770-2	2013	In order to overcome the difficulty in scarce availability of OP-specific antibody, here magnetic Fe3O4@TiO2 nanoparticles were used and adsorbed on the test strip through a small magnet inserted in the device to capture target OP-BChE through selective binding between TiO2 and OP moiety.	ferryl iron	98-103	butyrylcholinesterase	Homo sapiens	231-235
24084001-3	2013	Then, acetylcholinesterase (AChE) was adsorbed onto the GO/Fe3O4 surface to form GO/Fe3O4/AChE MNCs which was locally packed into PDMS microchannel simply with the help of external magnetic field to form an on-chip enzymatic microreactor.	ferryl iron	59-64	acetylcholinesterase (Cartwright blood group)	Homo sapiens	6-26
24084001-3	2013	Then, acetylcholinesterase (AChE) was adsorbed onto the GO/Fe3O4 surface to form GO/Fe3O4/AChE MNCs which was locally packed into PDMS microchannel simply with the help of external magnetic field to form an on-chip enzymatic microreactor.	ferryl iron	59-64	acetylcholinesterase (Cartwright blood group)	Homo sapiens	28-32
24084001-3	2013	Then, acetylcholinesterase (AChE) was adsorbed onto the GO/Fe3O4 surface to form GO/Fe3O4/AChE MNCs which was locally packed into PDMS microchannel simply with the help of external magnetic field to form an on-chip enzymatic microreactor.	ferryl iron	59-64	acetylcholinesterase (Cartwright blood group)	Homo sapiens	90-94
24084001-3	2013	Then, acetylcholinesterase (AChE) was adsorbed onto the GO/Fe3O4 surface to form GO/Fe3O4/AChE MNCs which was locally packed into PDMS microchannel simply with the help of external magnetic field to form an on-chip enzymatic microreactor.	ferryl iron	84-89	acetylcholinesterase (Cartwright blood group)	Homo sapiens	6-26
24084001-3	2013	Then, acetylcholinesterase (AChE) was adsorbed onto the GO/Fe3O4 surface to form GO/Fe3O4/AChE MNCs which was locally packed into PDMS microchannel simply with the help of external magnetic field to form an on-chip enzymatic microreactor.	ferryl iron	84-89	acetylcholinesterase (Cartwright blood group)	Homo sapiens	28-32
24084001-4	2013	The constructed GO/Fe3O4/AChE MNCs-based enzymatic microreactor not only have the magnetism of Fe3O4 NPs that make them conveniently manipulated by an external magnetic field, but also have the larger surface and excellent biocompatibility of graphene which can incorporate much more AChE molecules and well maintain their biological activity.	ferryl iron	19-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	25-29
24084001-4	2013	The constructed GO/Fe3O4/AChE MNCs-based enzymatic microreactor not only have the magnetism of Fe3O4 NPs that make them conveniently manipulated by an external magnetic field, but also have the larger surface and excellent biocompatibility of graphene which can incorporate much more AChE molecules and well maintain their biological activity.	ferryl iron	19-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	284-288
24084001-4	2013	The constructed GO/Fe3O4/AChE MNCs-based enzymatic microreactor not only have the magnetism of Fe3O4 NPs that make them conveniently manipulated by an external magnetic field, but also have the larger surface and excellent biocompatibility of graphene which can incorporate much more AChE molecules and well maintain their biological activity.	ferryl iron	95-100	acetylcholinesterase (Cartwright blood group)	Homo sapiens	25-29
24020883-6	2013	Greatly enhanced sensitivity was achieved by using Fe3O4/Au nanocomposites to enrich thiocholine, the hydrolysis product of active AChE, followed by electrochemical oxidative desorption of the adsorbed thiocholine.	ferryl iron	51-56	acetylcholinesterase (Cartwright blood group)	Homo sapiens	131-135
24079826-2	2013	The small molecules (CS2), a NIR fluorescent chromophore, can be fixed into the covalently grafted polymer shell of the NPs by chemical reaction through a covalent bond to obtain stable CS2 dotted NPs Fe3O4@SiO2@PPEGMA-co-PGMA@CS2.	ferryl iron	201-206	chorionic somatomammotropin hormone 2	Homo sapiens	186-189
24079826-2	2013	The small molecules (CS2), a NIR fluorescent chromophore, can be fixed into the covalently grafted polymer shell of the NPs by chemical reaction through a covalent bond to obtain stable CS2 dotted NPs Fe3O4@SiO2@PPEGMA-co-PGMA@CS2.	ferryl iron	201-206	chorionic somatomammotropin hormone 2	Homo sapiens	186-189
23208101-1	2013	In this study, a novel biomolecule immobilization approach has been proposed to the synthesis of multi-functional core-shell glucose oxidase-Au-polydopamine-Fe3O4 magnetic bionanoparticles (GOx-Au-PDA-Fe3O4 MBNPs) using the one-pot chemical polymerization method.	ferryl iron	157-162	hydroxyacid oxidase 1	Homo sapiens	190-193
23651652-0	2013	Reversal of multidrug resistance by magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA in glioblastoma cell line.	ferryl iron	54-59	ATP binding cassette subfamily B member 1	Homo sapiens	86-90
23479452-6	2013	We suggest that present findings propose the potential use of Fe3O4-based magnetic fluids as the therapeutic agents targeting insulin-associating amyloidosis.	ferryl iron	62-67	insulin	Homo sapiens	126-133
23651652-1	2013	OBJECTIVE: To investigate the reversal effects of MDR1 gene on multidrug resistance in the glioblastoma cell line BT325 by magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA.	ferryl iron	141-146	ATP binding cassette subfamily B member 1	Homo sapiens	50-54
23651652-1	2013	OBJECTIVE: To investigate the reversal effects of MDR1 gene on multidrug resistance in the glioblastoma cell line BT325 by magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA.	ferryl iron	141-146	ATP binding cassette subfamily B member 1	Homo sapiens	173-177
23651652-13	2013	CONCLUSION: After targeted transfection of the glioblastoma cell line with magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA, the expression of MDR1 at both the mRNA and protein level decreased, which increased sensitivity to chemotherapy in vitro.	ferryl iron	93-98	ATP binding cassette subfamily B member 1	Homo sapiens	125-129
23651652-13	2013	CONCLUSION: After targeted transfection of the glioblastoma cell line with magnetic chitosan-Fe3O4 nanoparticle-encapsulated MDR1 siRNA, the expression of MDR1 at both the mRNA and protein level decreased, which increased sensitivity to chemotherapy in vitro.	ferryl iron	93-98	ATP binding cassette subfamily B member 1	Homo sapiens	155-159
23892599-5	2013	MgNPs-Fe3O4 caused a dose-dependent increase in the CD44+ fraction of A549 cells.	ferryl iron	6-11	CD44 molecule (Indian blood group)	Homo sapiens	52-56
23892599-6	2013	MgNPs-Fe3O4 induced the expression of heme oxygenase-1 at a concentration of 1 mug/mL, and in a dose-dependent manner.	ferryl iron	6-11	heme oxygenase 1	Homo sapiens	38-54
23749081-3	2013	In this study, anti-CD34 antibody-coated magnetic nanoparticles (Fe3O4@PEG-CD34) are shown to have high affinity to stem cells.	ferryl iron	65-70	CD34 molecule	Homo sapiens	20-24
23749081-3	2013	In this study, anti-CD34 antibody-coated magnetic nanoparticles (Fe3O4@PEG-CD34) are shown to have high affinity to stem cells.	ferryl iron	65-70	CD34 molecule	Homo sapiens	75-79
23776514-0	2013	Synergistic removal of Pb(II), Cd(II) and humic acid by Fe3O4@mesoporous silica-graphene oxide composites.	ferryl iron	56-61	submaxillary gland androgen regulated protein 3B	Homo sapiens	23-29
32260953-5	2013	In vitro cytotoxicity tests suggest that the obtained GN-CNT-Fe3O4 hybrid is nontoxic for Chang liver cells, even at the high concentration of 80 mug mL-1, however, the 5-FU-loaded GN-CNT-Fe3O4 hybrid showed significant cytotoxic effects in HepG2 cells.	ferryl iron	61-66	L1 cell adhesion molecule	Mus musculus	150-154
23321558-0	2013	Sensitive electrochemical analysis of BRAF V600E mutation based on an amplification-refractory mutation system coupled with multienzyme functionalized Fe3O4/Au nanoparticles.	ferryl iron	151-156	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	38-42
23208101-1	2013	In this study, a novel biomolecule immobilization approach has been proposed to the synthesis of multi-functional core-shell glucose oxidase-Au-polydopamine-Fe3O4 magnetic bionanoparticles (GOx-Au-PDA-Fe3O4 MBNPs) using the one-pot chemical polymerization method.	ferryl iron	201-206	hydroxyacid oxidase 1	Homo sapiens	190-193
23208101-2	2013	Then, a high performance biosensor has been constructed by effectively attaching the proposed GOx-Au-PDA-Fe3O4 MBNPs to the surface of the magnetic glassy carbon electrode.	ferryl iron	105-110	hydroxyacid oxidase 1	Homo sapiens	94-97
23208101-3	2013	Scanning electron microscope, energy dispersive x-ray spectrometer, UV-vis spectroscopy, and electrochemical methods were used to characterize the GOx-Au-PDA-Fe3O4 MBNPs.	ferryl iron	158-163	hydroxyacid oxidase 1	Homo sapiens	147-150
23208101-4	2013	The resultant GOx-Au-PDA-Fe3O4 MBNPs not only have the magnetism of Fe3O4 nanoparticles which makes them easily manipulated by an external magnetic field, but also have the excellent biocompatibility of PDA to maintain the native structure of the GOx, and good conductivity of Au nanoparticles which can facilitate the direct electrochemistry of GOx in the biofilm.	ferryl iron	25-30	hydroxyacid oxidase 1	Homo sapiens	14-17
23208101-4	2013	The resultant GOx-Au-PDA-Fe3O4 MBNPs not only have the magnetism of Fe3O4 nanoparticles which makes them easily manipulated by an external magnetic field, but also have the excellent biocompatibility of PDA to maintain the native structure of the GOx, and good conductivity of Au nanoparticles which can facilitate the direct electrochemistry of GOx in the biofilm.	ferryl iron	25-30	hydroxyacid oxidase 1	Homo sapiens	247-250
23208101-4	2013	The resultant GOx-Au-PDA-Fe3O4 MBNPs not only have the magnetism of Fe3O4 nanoparticles which makes them easily manipulated by an external magnetic field, but also have the excellent biocompatibility of PDA to maintain the native structure of the GOx, and good conductivity of Au nanoparticles which can facilitate the direct electrochemistry of GOx in the biofilm.	ferryl iron	25-30	hydroxyacid oxidase 1	Homo sapiens	247-250
23208101-4	2013	The resultant GOx-Au-PDA-Fe3O4 MBNPs not only have the magnetism of Fe3O4 nanoparticles which makes them easily manipulated by an external magnetic field, but also have the excellent biocompatibility of PDA to maintain the native structure of the GOx, and good conductivity of Au nanoparticles which can facilitate the direct electrochemistry of GOx in the biofilm.	ferryl iron	68-73	hydroxyacid oxidase 1	Homo sapiens	14-17
23208101-5	2013	Hence, the present GOx-Au-PDA-Fe3O4 biofilm displays good linear amperometric response to glucose concentration ranging from 0.02 to 1.875 mM.	ferryl iron	30-35	hydroxyacid oxidase 1	Homo sapiens	19-22
32260801-6	2013	Importantly, the substitution of Fe3O4 for CaO in the MBG scaffolds induced a slower ion dissolution rate and more significant potential to stabilize the pH environment, and facilitated osteoblast cell proliferation, alkaline phosphatase (ALP) activity and osteogenic expression.	ferryl iron	33-38	alkaline phosphatase, placental	Homo sapiens	217-237
23507756-2	2013	The rapid and room temperature synthesis of magnetic nanoparticles was achieved using the hydroxylamine reduction of HAuCl4 on the surface of ethylenediaminetetraacetic acid (EDTA)-immobilized iron (magnetite Fe3O4) nanoparticles in the presence of an aqueous solution of hexadecyltrimetylammonium bromide (CTAB) as a dispersant.	ferryl iron	209-214	outer membrane receptor FepA	Escherichia coli	193-197
28809208-0	2013	An Ultrasensitive Electrochemical Immunosensor for HIV p24 Based on Fe3O4@SiO2 Nanomagnetic Probes and Nanogold Colloid-Labeled Enzyme-Antibody Copolymer as Signal Tag.	ferryl iron	68-73	transmembrane p24 trafficking protein 2	Homo sapiens	55-58
32260801-6	2013	Importantly, the substitution of Fe3O4 for CaO in the MBG scaffolds induced a slower ion dissolution rate and more significant potential to stabilize the pH environment, and facilitated osteoblast cell proliferation, alkaline phosphatase (ALP) activity and osteogenic expression.	ferryl iron	33-38	alkaline phosphatase, placental	Homo sapiens	239-242
23755658-3	2013	The Fe3O4 particles are first modified using AAc monomers.	ferryl iron	4-9	glycine-N-acyltransferase	Homo sapiens	45-48
23755658-4	2013	The AAc-modified Fe3O4 cores are then copolymerized with NIPAAm to form the latex shell.	ferryl iron	17-22	glycine-N-acyltransferase	Homo sapiens	4-7
23878789-0	2013	Inhibition of hTERT Gene Expression by Silibinin-Loaded PLGA-PEG-Fe3O4 in T47D Breast Cancer Cell Line.	ferryl iron	65-70	telomerase reverse transcriptase	Homo sapiens	14-19
32260817-6	2013	The Fe3O4@C NPs based cholesterol biosensor shows response time of 60 s, a linearity range of 25-500 mg dl-1, a sensitivity of 193 nA mg-1 dl cm-2 and a Michaelis-Menten constant of 1.44 mg dl-1.	ferryl iron	4-9	delta like canonical Notch ligand 1	Homo sapiens	104-108
32260817-6	2013	The Fe3O4@C NPs based cholesterol biosensor shows response time of 60 s, a linearity range of 25-500 mg dl-1, a sensitivity of 193 nA mg-1 dl cm-2 and a Michaelis-Menten constant of 1.44 mg dl-1.	ferryl iron	4-9	delta like canonical Notch ligand 1	Homo sapiens	190-194
24348038-1	2013	Transferrin (Tf) was immobilized onto Fe3O4@SiO2 nanoparticles with high doxorubicin (DOX) loading (TfDMP), for dual targeting of cancer, by chemically coupling both Tf and DOX with dual-function magnetic nanoparticles (DMPs) using a multi-armed crosslinker, poly-L-glutamic acid.	ferryl iron	38-43	transferrin	Homo sapiens	0-11
24348038-0	2013	Immobilized transferrin Fe3O4@SiO2 nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery.	ferryl iron	24-29	transferrin	Homo sapiens	12-23
24575623-9	2013	With the assistance of the Fe3O4 coated metal target and a relatively low laser fluence &lt; or =700 Jm(-2)), proteins such as insulin, ubiquitin and myoglobin were successfully ionized.	ferryl iron	27-32	insulin	Homo sapiens	127-134
23610522-0	2013	Paclitaxel-Fe3O4 nanoparticles inhibit growth of CD138(-) CD34(-) tumor stem-like cells in multiple myeloma-bearing mice.	ferryl iron	11-16	syndecan 1	Mus musculus	49-54
23610522-0	2013	Paclitaxel-Fe3O4 nanoparticles inhibit growth of CD138(-) CD34(-) tumor stem-like cells in multiple myeloma-bearing mice.	ferryl iron	11-16	CD34 antigen	Mus musculus	58-62
23610522-3	2013	The purpose of this study was to investigate the inhibitory effect of paclitaxel-loaded Fe3O4 nanoparticles (PTX-NPs) on CD138(-) CD34(-) tumor stem cells in multiple myeloma-bearing mice.	ferryl iron	88-93	syndecan 1	Mus musculus	121-126
23610522-3	2013	The purpose of this study was to investigate the inhibitory effect of paclitaxel-loaded Fe3O4 nanoparticles (PTX-NPs) on CD138(-) CD34(-) tumor stem cells in multiple myeloma-bearing mice.	ferryl iron	88-93	CD34 antigen	Mus musculus	130-134
22934734-2	2012	Clusters of the type [Fe(4)S(4)(SAr)(4)](2-) (Ar = Ph, C(6)H(4)-3-F) are generated in Me(2)SO by redox reactions of [Fe(4)S(4)(SEt)(4)](2-) with 2 equiv of ArSSAr.	ferryl iron	22-28	sarcosine dehydrogenase	Homo sapiens	32-35
22111689-0	2012	A facile synthesis of PEG-coated magnetite (Fe3O4) nanoparticles and their prevention of the reduction of cytochrome c.	ferryl iron	44-49	cytochrome c, somatic	Homo sapiens	106-118
22769032-0	2012	Magnetic Fe3O4@Au composite-enhanced surface plasmon resonance for ultrasensitive detection of magnetic nanoparticle-enriched alpha-fetoprotein.	ferryl iron	9-14	alpha fetoprotein	Homo sapiens	126-143
22320223-0	2012	Novel magnetic Fe3O4@CdSe composite quantum dot-based electrochemiluminescence detection of thrombin by a multiple DNA cycle amplification strategy.	ferryl iron	15-20	coagulation factor II, thrombin	Homo sapiens	92-100
22265502-0	2012	Highly sensitive thrombin detection by matrix assisted laser desorption ionization-time of flight mass spectrometry with aptamer functionalized core-shell Fe3O4@C@Au magnetic microspheres.	ferryl iron	155-160	coagulation factor II, thrombin	Homo sapiens	17-25
22099656-0	2011	Application of chitosan/Fe3O4 microsphere-graphene composite modified carbon ionic liquid electrode for the electrochemical detection of the PCR product of soybean Lectin gene sequence.	ferryl iron	24-29	LOW QUALITY PROTEIN: lectin	Glycine max	164-170
22888247-0	2012	Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells.	ferryl iron	55-60	AKT serine/threonine kinase 1	Homo sapiens	112-115
21333751-0	2011	Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo.	ferryl iron	0-5	caspase 8	Homo sapiens	63-72
22409060-7	2011	The nanoparticles treatment caused cell cycle arrest in G2/M phase and the mRNA levels of P53 increased when PC12 cells were incubated with different concentrations Fe3O4 NPs.	ferryl iron	165-170	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	90-93
22409060-9	2011	In summary, exposure to Fe3O4 NPs resulted in a dose-dependent cytotoxicity in cultured PC12 cells that was associated with increased P53 gene expression and much attention should be paid to the potential impact of Fe3O4 NPs on the central nervous system.	ferryl iron	24-29	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	134-137
22052564-0	2011	Core/shell Fe3O4 @SiO2 nanoparticles modified with PAH as a vector for EGFP plasmid DNA delivery into HeLa cells.	ferryl iron	11-16	phenylalanine hydroxylase	Homo sapiens	51-54
21333751-0	2011	Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo.	ferryl iron	0-5	poly(ADP-ribose) polymerase 1	Homo sapiens	73-77
21514816-0	2011	Oxidative desorption of thiocholine assembled on core-shell Fe3O4/AuNPs magnetic nanocomposites for highly sensitive determination of acetylcholinesterase activity: an exposure biomarker of organophosphates.	ferryl iron	60-65	acetylcholinesterase (Cartwright blood group)	Homo sapiens	134-154
21421215-0	2011	Preparation of Fe3O4@Ag SERS substrate and its application in environmental Cr(VI) analysis.	ferryl iron	15-20	seryl-tRNA synthetase 1	Homo sapiens	24-28
21435100-0	2011	Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions.	ferryl iron	27-32	caspase 8	Homo sapiens	95-104
21435100-3	2011	In the present study we investigate the hypothesis that the unique water dispersible oleic acid-Triton X-100-coated Fe3O4 nanoparticles loaded with HCPT disrupt epithelial cell-cell junctions and induce human lung cancer cell apoptosis through the caspase-8 pathway.	ferryl iron	116-121	caspase 8	Homo sapiens	248-257
21621154-4	2011	METHODS: We constructed recombinant plasmid PEGFP-AFP-hTNFalpha, which was transfected into AFP positive HepG2 cells and AFP negative Hela cells by PEG-PEI/Fe3O4 nanomagnetic fluid.	ferryl iron	156-161	tumor necrosis factor	Homo sapiens	54-63
21621154-9	2011	RESULTS: Plasmid PEGFP-AFP-hTNFalpha delivered by PEG-PEI/Fe3O4 nanomagnetic fluid was successfully transfected into HepG2 cells and expressed in the HepG2 cells.	ferryl iron	58-63	alpha fetoprotein	Homo sapiens	23-26
21621154-9	2011	RESULTS: Plasmid PEGFP-AFP-hTNFalpha delivered by PEG-PEI/Fe3O4 nanomagnetic fluid was successfully transfected into HepG2 cells and expressed in the HepG2 cells.	ferryl iron	58-63	tumor necrosis factor	Homo sapiens	27-36
21621154-10	2011	The transfection efficacy of hTNFalpha gene delivered by PEG-PEI/Fe3O4 nanomagnetic fluid was superior to that of hTNFalpha gene delivered by lipofectamine in HepG2 cells.	ferryl iron	65-70	tumor necrosis factor	Homo sapiens	29-38
21621154-13	2011	CONCLUSION: PEG-PEI/Fe3O4 nanomagnetic fluid successfully transfected PEGFP-AFP-hTNFalpha into HepG2 cells and induced expression of hTNFalpha gene in the HepG2 cells, thus showing promise as a gene vector for liver cancer gene therapy.	ferryl iron	20-25	alpha fetoprotein	Homo sapiens	76-79
21621154-13	2011	CONCLUSION: PEG-PEI/Fe3O4 nanomagnetic fluid successfully transfected PEGFP-AFP-hTNFalpha into HepG2 cells and induced expression of hTNFalpha gene in the HepG2 cells, thus showing promise as a gene vector for liver cancer gene therapy.	ferryl iron	20-25	tumor necrosis factor	Homo sapiens	80-89
21621154-13	2011	CONCLUSION: PEG-PEI/Fe3O4 nanomagnetic fluid successfully transfected PEGFP-AFP-hTNFalpha into HepG2 cells and induced expression of hTNFalpha gene in the HepG2 cells, thus showing promise as a gene vector for liver cancer gene therapy.	ferryl iron	20-25	tumor necrosis factor	Homo sapiens	133-142
21518493-5	2011	It is concluded that the combination treatment of MNP-Fe3O4 and daunorubicin efficiently inhibits growth and induces apoptosis in Raji cell line, while the activation of P53 and down-regulation of NF-kappaB may play important roles.	ferryl iron	54-59	tumor protein p53	Homo sapiens	170-173
21558026-2	2011	A catalytic redox cycle in the PHD"s iron center that results in the formation of a ferryl (Fe(+4)) intermediate has been reported to be responsible for the hydroxylation and subsequent degradation of HIF-1alpha under normoxia.	ferryl iron	92-98	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	201-211
20728321-0	2010	Synthesis and characterization of Fe3O4@SiO2@poly-L-alanine, peptide brush-magnetic microspheres through NCA chemistry for drug delivery and enrichment of BSA.	ferryl iron	34-39	CEA cell adhesion molecule 6	Homo sapiens	105-108
21237311-0	2011	Magnetic loading of tyrosinase-Fe3O4/mesoporous silica core/shell microspheres for high sensitive electrochemical biosensing.	ferryl iron	31-36	tyrosinase	Homo sapiens	20-30
21076738-0	2011	A kinetic study on the conversion of cis-2-butene with deuterium on a Pd/Fe3O4 model catalyst.	ferryl iron	73-78	suppressor of cytokine signaling 2	Homo sapiens	37-42
20207773-2	2011	The Fe(2+)/NO-3 /OH(-) molar ratio of 3 : 1 : 5 led to the formation of magnetic nanoparticles mainly composed of magnetite (Fe3O4) and maghemite (gamma-Fe2O3).	ferryl iron	125-130	NBL1, DAN family BMP antagonist	Homo sapiens	11-15
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	36-41	tumor protein p53	Homo sapiens	84-87
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	36-41	nuclear factor kappa B subunit 1	Homo sapiens	117-126
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	36-41	tumor protein p53	Homo sapiens	266-269
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	36-41	nuclear factor kappa B subunit 1	Homo sapiens	274-283
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	206-211	tumor protein p53	Homo sapiens	266-269
21187919-8	2010	Furthermore, the combination of MNP-Fe3O4 with adriamycin or daunorubicin increased p53 protein levels and decreased NF-kappaB protein levels more than adriamycin or daunorubicin alone, indicating that MNP-Fe3O4 could enhance the effect of chemotherapeutic drugs on p53 and NF-kappaB.	ferryl iron	206-211	nuclear factor kappa B subunit 1	Homo sapiens	274-283
20656467-4	2010	Moreover, glucose oxidase (GOx) and citrate-capped gold (Au) NPs, having negative charges, can be easily self-assembled at the surface of cationic PDDA-Fe3O4 NPs.	ferryl iron	152-157	hydroxyacid oxidase 1	Homo sapiens	10-25
20959824-10	2010	Fluorescent microscopy confirmed the presence of anti-IGFBP7 sdAb and anti-IGFBP7 sdAb-PEGylated Fe3O4 NPs selectively in GBM vessels.	ferryl iron	97-102	insulin like growth factor binding protein 7	Homo sapiens	75-81
20656467-4	2010	Moreover, glucose oxidase (GOx) and citrate-capped gold (Au) NPs, having negative charges, can be easily self-assembled at the surface of cationic PDDA-Fe3O4 NPs.	ferryl iron	152-157	hydroxyacid oxidase 1	Homo sapiens	27-30
20656467-5	2010	Without the requirement of a peroxidise enzyme, the composites of PDDA-Fe3O4 NPs and GOx effectively catalyzes the H2O2-mediated oxidation of 2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonate acid) (ABTS) in the presence of glucose.	ferryl iron	71-76	hydroxyacid oxidase 1	Homo sapiens	85-88
20957165-0	2010	Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and MDR1 shRNA expression vector in leukemia cells.	ferryl iron	45-50	ATP binding cassette subfamily B member 1	Homo sapiens	98-102
21137737-1	2010	We first demonstrate a simple "one-pot" method to synthesis uniform Fe3O4 hollow microspheres in the presence of PEG in ethylene glycol by using urea to control their morphologies.	ferryl iron	68-73	progestagen associated endometrial protein	Homo sapiens	113-116
20481518-1	2010	The tetranuclear iron complex Fe(4)[MeC(CH(2)S)(3)](2)(CO)(8) (1) functions like a hydrogenase to catalyze proton reduction to H(2) in the presence of 2,6-dimethylpyridinium acid (LutH(+)).	ferryl iron	30-35	C-C motif chemokine ligand 28	Homo sapiens	36-39
20428565-3	2010	Here we present Fe L(2,3)-edge X-ray absorption spectra of these proteins in physiological solutions, which reveal clear differences in their electronic structures, in that pi back-donation of the Fe atom occurs in catalase, which confers on it a partial ferryl (Fe(4+)) character, while this is not the case in methaemoglobin.	ferryl iron	263-270	catalase	Homo sapiens	215-223