PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
27307252-2	2016	UDP-glucose dehydrogenase (UGDH) catalyzes the NAD(+)-dependent oxidation of UDP-glucose to UDP-glucuronate, an essential precursor for androgen inactivation by the prostate glucuronidation enzymes UGT2B15 and UGT2B17.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
27505673-3	2016	Glucose deprivation induces the activation of PKA, which phosphorylates URI at Ser-371, resulting in PP1gamma release and URI-mediated OGT inhibition.	Uridine Diphosphate Glucose	72-75	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	Mus musculus	135-138
27505673-6	2016	Accordingly, mice expressing non-phosphorylatable URI (S371A) in hepatocytes exhibit high OGT activity and c-MYC stabilization, accelerating liver tumorigenesis in agreement with c-MYC oncogenic functions.	Uridine Diphosphate Glucose	50-53	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	Mus musculus	90-93
27491546-10	2016	To further enhance the potential glycosylation activity of S. cerevisiae, two genes encoding phosphoglucomutase and UTP-glucose-1-phosphate uridylyltransferase involved in the synthetic system of uridine diphosphate glucose were over-expressed in S. cerevisiae.	Uridine Diphosphate Glucose	196-223	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	116-159
27466186-2	2016	Galactosemia I results from loss of galactose-1-phosphate uridyltransferase (GALT), which converts galactose-1-phosphate + UDP-glucose to glucose-1-phosphate + UDP-galactose.	Uridine Diphosphate Glucose	123-134	Galactose-1-phosphate uridylyltransferase	Drosophila melanogaster	77-81
27466186-4	2016	Galactosemia III results from the loss of UDP-galactose 4"-epimerase (GALE), which interconverts UDP-galactose and UDP-glucose, as well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	115-126	UDP-galactose 4'-epimerase	Drosophila melanogaster	42-68
27466186-4	2016	Galactosemia III results from the loss of UDP-galactose 4"-epimerase (GALE), which interconverts UDP-galactose and UDP-glucose, as well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	115-126	UDP-galactose 4'-epimerase	Drosophila melanogaster	70-74
27307252-2	2016	UDP-glucose dehydrogenase (UGDH) catalyzes the NAD(+)-dependent oxidation of UDP-glucose to UDP-glucuronate, an essential precursor for androgen inactivation by the prostate glucuronidation enzymes UGT2B15 and UGT2B17.	Uridine Diphosphate Glucose	0-11	UDP glucuronosyltransferase family 2 member B15	Homo sapiens	198-205
27307252-2	2016	UDP-glucose dehydrogenase (UGDH) catalyzes the NAD(+)-dependent oxidation of UDP-glucose to UDP-glucuronate, an essential precursor for androgen inactivation by the prostate glucuronidation enzymes UGT2B15 and UGT2B17.	Uridine Diphosphate Glucose	0-11	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	210-217
26833384-1	2016	In Brassica napus, suppression of the key biosynthetic enzyme UDP-glucose:sinapic acid glucosyltransferase (UGT84A9) inhibits the biosynthesis of sinapine (sinapoylcholine), the major phenolic component of seeds.	Uridine Diphosphate Glucose	62-73	UDP-glycosyltransferase 84A2-like	Brassica napus	108-115
26976766-8	2016	To further confirm the specific effect of geniposide on P2Y14 receptor and downstream signaling pathways, we set up a UDP-glucose (an agonist of the P2Y14 receptor) stimulated model.	Uridine Diphosphate Glucose	118-129	purinergic receptor P2Y14	Rattus norvegicus	149-154
27198584-1	2016	The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the reaction of UDP-glucose to UDP-glucuronate through two successive NAD(+)-dependent oxidation steps.	Uridine Diphosphate Glucose	11-22	UDP-glucose 6-dehydrogenase	Homo sapiens	38-42
26981769-6	2016	Our data bring strong support to the following scenario: bacteria co-opt the host transporter SLC35D2 to import UDP-glucose into the vacuole, where it serves as substrate for de novo glycogen synthesis, through a remarkable adaptation of the bacterial glycogen synthase.	Uridine Diphosphate Glucose	112-123	solute carrier family 35 member D2	Homo sapiens	94-101
26582015-0	2016	Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase.	Uridine Diphosphate Glucose	23-34	UDP-glucose 6-dehydrogenase	Homo sapiens	121-148
26582015-1	2016	OBJECTIVES: To use permeabilized cells of the fission yeast, Schizosaccharomyces pombe, that expresses human UDP-glucose 6-dehydrogenase (UGDH, EC 1.1.1.22), for the production of UDP-glucuronic acid from UDP-glucose.	Uridine Diphosphate Glucose	109-120	UDP-glucose 6-dehydrogenase	Homo sapiens	138-142
26498530-1	2015	Ugp1, UDP-glucose pyrophosphorylase, plays an important role in carbohydrate metabolism because it provides UDP-glucose that is a pivotal metabolite in several metabolic pathways in Saccharomyces cerevisiae.	Uridine Diphosphate Glucose	6-17	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	0-4
26264414-5	2016	The conversion occurred via regeneration of UDP-glucose by AtSUS1.	Uridine Diphosphate Glucose	44-55	sucrose synthase 1	Arabidopsis thaliana	59-65
26344854-1	2015	UDP-galactose 4-epimerase (GalE) catalyzes the interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal), which is a pivotal step in the Leloir pathway for d-galactose metabolism.	Uridine Diphosphate Glucose	66-77	UDP-galactose-4-epimerase	Homo sapiens	27-31
26344854-1	2015	UDP-galactose 4-epimerase (GalE) catalyzes the interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal), which is a pivotal step in the Leloir pathway for d-galactose metabolism.	Uridine Diphosphate Glucose	79-86	UDP-galactose-4-epimerase	Homo sapiens	27-31
26160581-8	2015	Recombinant UGT85K14 expressed in Escherichia coli is able to transfer a glucose moiety from UDP-glucose to the hydroxy group of furaneol, indicating that this gene might be UDP-glucose: furaneol glucosyltransferase in Muscat Bailey A.	Uridine Diphosphate Glucose	93-104	cinnamate beta-D-glucosyltransferase-like	Vitis vinifera	196-215
26497456-0	2016	Inhibitory Role of Greatwall-Like Protein Kinase Rim15p in Alcoholic Fermentation via Upregulating the UDP-Glucose Synthesis Pathway in Saccharomyces cerevisiae.	Uridine Diphosphate Glucose	103-114	protein kinase RIM15	Saccharomyces cerevisiae S288C	49-55
26497456-2	2016	In the present study, we performed intracellular metabolic profiling analysis and revealed that deletion of the RIM15 gene in a laboratory strain impaired glucose-anabolic pathways through the synthesis of UDP-glucose (UDPG).	Uridine Diphosphate Glucose	206-217	protein kinase RIM15	Saccharomyces cerevisiae S288C	112-117
26240141-3	2015	The corresponding biochemical characterization of CalS8 reveals CalS8 as one of the first characterized base-permissive UGDH homologs with a >15-fold preference for TDP-Glc over UDP-Glc.	Uridine Diphosphate Glucose	181-188	UDP-glucose 6-dehydrogenase	Homo sapiens	120-124
26160581-0	2015	Molecular cloning and characterization of UDP-glucose: furaneol glucosyltransferase gene from grapevine cultivar Muscat Bailey A (Vitis labrusca x V. vinifera).	Uridine Diphosphate Glucose	42-53	cinnamate beta-D-glucosyltransferase-like	Vitis vinifera	64-83
26188548-1	2015	Ugp1, a UDP-glucose pyrophosphorylase, is essential for various cellular activities in Saccharomyces cerevisiae because its product, UDP-glucose, is a sole glucosyl donor in several metabolic pathways.	Uridine Diphosphate Glucose	8-19	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	0-4
26160581-8	2015	Recombinant UGT85K14 expressed in Escherichia coli is able to transfer a glucose moiety from UDP-glucose to the hydroxy group of furaneol, indicating that this gene might be UDP-glucose: furaneol glucosyltransferase in Muscat Bailey A.	Uridine Diphosphate Glucose	174-185	cinnamate beta-D-glucosyltransferase-like	Vitis vinifera	196-215
26197338-8	2015	Sucrose synthase AtSUS1 was employed to regenerate UDP-glucose during the glucosylation reaction.	Uridine Diphosphate Glucose	51-62	sucrose synthase 1	Arabidopsis thaliana	17-23
26048992-8	2015	Although AMPK did not affect the phosphorylation or expression of GlcCer synthase, the amount of UDP-glucose, an activated form of glucose required for GlcCer synthesis, decreased under AMPK-activating conditions.	Uridine Diphosphate Glucose	97-108	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	186-190
26048992-9	2015	Importantly, the UDP-glucose pyrophosphatase Nudt14, which degrades UDP-glucose, generating UMP and glucose 1-phosphate, was phosphorylated and activated by AMPK.	Uridine Diphosphate Glucose	17-28	nudix hydrolase 14	Homo sapiens	45-51
26048992-9	2015	Importantly, the UDP-glucose pyrophosphatase Nudt14, which degrades UDP-glucose, generating UMP and glucose 1-phosphate, was phosphorylated and activated by AMPK.	Uridine Diphosphate Glucose	17-28	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	157-161
26048992-10	2015	On the other hand, suppression of Nudt14 by siRNA had little effect on UDP-glucose levels, indicating that mammalian cells have an alternative UDP-glucose pyrophosphatase that mainly contributes to the reduction of UDP-glucose under AMPK-activating conditions.	Uridine Diphosphate Glucose	143-154	nudix hydrolase 14	Homo sapiens	34-40
26048992-10	2015	On the other hand, suppression of Nudt14 by siRNA had little effect on UDP-glucose levels, indicating that mammalian cells have an alternative UDP-glucose pyrophosphatase that mainly contributes to the reduction of UDP-glucose under AMPK-activating conditions.	Uridine Diphosphate Glucose	143-154	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	233-237
25868749-1	2015	The P2Y14 receptor (P2Y14R) is a Gi protein-coupled receptor that is activated by uracil nucleotides UDP and UDP-glucose.	Uridine Diphosphate Glucose	109-120	purinergic receptor P2Y14	Homo sapiens	4-18
25868749-1	2015	The P2Y14 receptor (P2Y14R) is a Gi protein-coupled receptor that is activated by uracil nucleotides UDP and UDP-glucose.	Uridine Diphosphate Glucose	109-120	purinergic receptor P2Y14	Homo sapiens	20-26
25868749-6	2015	The glucose moiety of UDP-glucose docked in a secondary subpocket at the P2Y14R homology model.	Uridine Diphosphate Glucose	22-33	purinergic receptor P2Y14	Homo sapiens	73-79
25694454-6	2015	Our analysis reveals the unexpected collaboration of the cytosolic AAA-ATPase p97 and the luminal quality control factor UDP-glucose:glycoprotein glucosyltransferase (UGGT1) in a novel, BiP- and CNX-independent checkpoint.	Uridine Diphosphate Glucose	121-132	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	167-172
25964538-0	2015	Reduced UDP-glucose Levels Are Associated with P-glycoprotein Over-expression in L1210 Cells and Limit Glucosylceramide Synthase Activity.	Uridine Diphosphate Glucose	8-19	phosphoglycolate phosphatase	Mus musculus	47-61
25964538-0	2015	Reduced UDP-glucose Levels Are Associated with P-glycoprotein Over-expression in L1210 Cells and Limit Glucosylceramide Synthase Activity.	Uridine Diphosphate Glucose	8-19	UDP-glucose ceramide glucosyltransferase	Mus musculus	103-128
25964538-4	2015	Previously, we described a reduction in the uridine diphosphate (UDP)-glucose contents of mouse leukemia cells (R) expressing Pgp due to vincristine selection compared to parental L1210 cells (S).	Uridine Diphosphate Glucose	65-77	phosphoglycolate phosphatase	Mus musculus	126-129
25964538-9	2015	RESULTS: We detected significantly reduced levels of C12-NBD-ceramide glycosylation and reduced UDP-glucose contents in Pgp-positive R and T-cells compared to S cells.	Uridine Diphosphate Glucose	96-107	phosphoglycolate phosphatase	Mus musculus	120-123
25964538-13	2015	CONCLUSION: These evidence indicates that the down-regulation of UDP-glucose contents in Pgp-positive L1210 cells is responsible for their collateral sensitivity to ceramide-induced apoptosis.	Uridine Diphosphate Glucose	65-76	phosphoglycolate phosphatase	Mus musculus	89-92
25799465-5	2015	We found that UDP-glucose increases pro-inflammatory chemokine expression in ICs as well as MDCK-C11 cells, and UDP-glucose activates the MEK1/2-ERK1/2 pathway in MDCK-C11 cells.	Uridine Diphosphate Glucose	112-123	mitogen-activated protein kinase 1	Canis lupus familiaris	145-151
25694454-6	2015	Our analysis reveals the unexpected collaboration of the cytosolic AAA-ATPase p97 and the luminal quality control factor UDP-glucose:glycoprotein glucosyltransferase (UGGT1) in a novel, BiP- and CNX-independent checkpoint.	Uridine Diphosphate Glucose	121-132	heat shock protein family A (Hsp70) member 5	Homo sapiens	186-189
25519837-2	2015	The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjugate xenobiotics, including drugs and endobiotics such as metabolic byproducts, hormones, and signaling molecules.	Uridine Diphosphate Glucose	97-108	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	4-8
25605538-1	2015	The UDP-sulfoquinovose synthase Agl3 from Sulfolobus acidocaldarius converts UDP-D-glucose and sulfite to UDP-sulfoquinovose, the activated form of sulfoquinovose required for its incorporation into glycoconjugates.	Uridine Diphosphate Glucose	77-90	K-box region and MADS-box transcription factor family protein	Arabidopsis thaliana	32-36
25799465-5	2015	We found that UDP-glucose increases pro-inflammatory chemokine expression in ICs as well as MDCK-C11 cells, and UDP-glucose activates the MEK1/2-ERK1/2 pathway in MDCK-C11 cells.	Uridine Diphosphate Glucose	112-123	dual specificity mitogen-activated protein kinase kinase 2	Canis lupus familiaris	138-144
25519837-2	2015	The UGT1 and UGT2 enzymes use UDP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjugate xenobiotics, including drugs and endobiotics such as metabolic byproducts, hormones, and signaling molecules.	Uridine Diphosphate Glucose	97-108	solute carrier family 35 member A2	Homo sapiens	13-17
25201731-1	2014	UDP-galactose-4-epimerase (GALE) is a key enzyme catalyzing the interconversion of UDP-glucose and UDP-galactose, as well as UDP-N-acetylglucosamine and UDP-N-acetylgalactosamine, which are all precursors for the proteoglycans (PGs) synthesis.	Uridine Diphosphate Glucose	83-94	UDP-galactose-4-epimerase	Homo sapiens	0-25
25505447-4	2014	In ogt-1 null animals, steady-state levels of UDP-GlcNAc/UDP-GalNAc and UDP-glucose were substantially elevated.	Uridine Diphosphate Glucose	72-83	Protein O-GlcNAc transferase;UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase	Caenorhabditis elegans	3-8
25150110-5	2014	The natural ligands, NAD(+) and UDP-glucose, stabilize GALE.	Uridine Diphosphate Glucose	32-43	UDP-galactose-4-epimerase	Homo sapiens	55-59
25326312-1	2014	Classic galactosemia (CG) is an autosomal recessive disorder resulting from loss of galactose-1-phosphate uridyltransferase (GALT), which catalyzes conversion of galactose-1-phosphate and uridine diphosphate (UDP)-glucose to glucose-1-phosphate and UDP-galactose, immediately upstream of UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine synthesis.	Uridine Diphosphate Glucose	209-221	Galactose-1-phosphate uridylyltransferase	Drosophila melanogaster	84-123
25326312-1	2014	Classic galactosemia (CG) is an autosomal recessive disorder resulting from loss of galactose-1-phosphate uridyltransferase (GALT), which catalyzes conversion of galactose-1-phosphate and uridine diphosphate (UDP)-glucose to glucose-1-phosphate and UDP-galactose, immediately upstream of UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine synthesis.	Uridine Diphosphate Glucose	209-221	Galactose-1-phosphate uridylyltransferase	Drosophila melanogaster	125-129
26190959-2	2014	We show here how UDP-glucose 6-dehydrogenase (hUGDH) and UDP-xylose synthase 1 (hUXS) from Homo sapiens can be used for the efficient production of pure UDP-alpha-xylose from UDP-glucose.	Uridine Diphosphate Glucose	17-28	UDP-glucose 6-dehydrogenase	Homo sapiens	46-51
26190959-3	2014	In a mimic of the natural biosynthetic route, UDP-glucose is converted to UDP-glucuronic acid by hUGDH, followed by subsequent formation of UDP-xylose by hUXS.	Uridine Diphosphate Glucose	46-57	UDP-glucose 6-dehydrogenase	Homo sapiens	97-102
25201731-1	2014	UDP-galactose-4-epimerase (GALE) is a key enzyme catalyzing the interconversion of UDP-glucose and UDP-galactose, as well as UDP-N-acetylglucosamine and UDP-N-acetylgalactosamine, which are all precursors for the proteoglycans (PGs) synthesis.	Uridine Diphosphate Glucose	83-94	UDP-galactose-4-epimerase	Homo sapiens	27-31
25038930-2	2014	In these systems, one-pot reactions for the synthesis of UDP-alpha-D-glucose and UDP-alpha-D-2-deoxyglucose were modified and combined with a glycosyltransferase (GT) from Bacillus licheniformis DSM-13 to afford C-3 and C-6 position modified glucose and 2-deoxyglucose conjugated novel alpha-mangostin derivatives.	Uridine Diphosphate Glucose	57-76	glycosyltransferase family 2 protein	Bacillus licheniformis DSM 13 = ATCC 14580	142-161
25038930-2	2014	In these systems, one-pot reactions for the synthesis of UDP-alpha-D-glucose and UDP-alpha-D-2-deoxyglucose were modified and combined with a glycosyltransferase (GT) from Bacillus licheniformis DSM-13 to afford C-3 and C-6 position modified glucose and 2-deoxyglucose conjugated novel alpha-mangostin derivatives.	Uridine Diphosphate Glucose	57-76	glycosyltransferase family 2 protein	Bacillus licheniformis DSM 13 = ATCC 14580	163-165
24911208-1	2014	Extracellular UDP-glucose can activate the purinergic P2Y14 receptor.	Uridine Diphosphate Glucose	14-25	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	54-59
24909956-10	2014	These experiments showed a migratory function of the receptor by treatment with UDP-glucose and leukotriene LTD4, two GPR17 pharmacological agonists.	Uridine Diphosphate Glucose	80-91	G protein-coupled receptor 17	Mus musculus	118-123
24239874-1	2014	Glycogen synthesis is initiated by self-glucosylation of the glycosyltransferases glycogenin-1 and -2 that, in the presence of UDP-glucose, form both the first glucose-O-tyrosine linkage, and then stepwise add a series of alpha1,4-linked glucoses to a growing chain of variable length.	Uridine Diphosphate Glucose	127-138	glycogenin 1	Homo sapiens	82-101
25094044-1	2014	Here we report glycan structures and their position of attachment to a carrier protein, uridine 5"-diphosphate-glucose: glycoprotein glucosyltransferase (UGGT1), as detected using tandem mass spectrometry.	Uridine Diphosphate Glucose	88-118	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	154-159
24779768-2	2014	Previous work has identified one thiohydroximate S-glucosyltransferase, UGT74B1, with an important role in the core pathway, but also made clear that this enzyme functions redundantly and cannot be the sole UDP-glucose dependent glucosyltransferase (UGT) in glucosinolate synthesis.	Uridine Diphosphate Glucose	207-218	UDP-glucosyl transferase 74B1	Arabidopsis thaliana	72-79
24847057-0	2014	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	Uridine Diphosphate Glucose	14-25	purinergic receptor P2Y14	Homo sapiens	36-50
24847057-0	2014	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	Uridine Diphosphate Glucose	14-25	signal transducer and activator of transcription 3	Homo sapiens	63-113
24847057-0	2014	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	Uridine Diphosphate Glucose	14-25	signal transducer and activator of transcription 3	Homo sapiens	115-120
24847057-0	2014	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	Uridine Diphosphate Glucose	14-25	hyaluronan synthase 2	Homo sapiens	160-181
24847057-0	2014	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	Uridine Diphosphate Glucose	14-25	hyaluronan synthase 2	Homo sapiens	183-187
24847057-2	2014	We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid induction of hyaluronan synthase 2 (HAS2), and an increase of hyaluronan synthesis.	Uridine Diphosphate Glucose	84-95	hyaluronan synthase 2	Homo sapiens	178-199
24847057-2	2014	We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid induction of hyaluronan synthase 2 (HAS2), and an increase of hyaluronan synthesis.	Uridine Diphosphate Glucose	84-95	hyaluronan synthase 2	Homo sapiens	201-205
24847057-2	2014	We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid induction of hyaluronan synthase 2 (HAS2), and an increase of hyaluronan synthesis.	Uridine Diphosphate Glucose	97-104	hyaluronan synthase 2	Homo sapiens	178-199
24847057-2	2014	We found that small amounts of UDP-sugars were released from keratinocytes and that UDP-glucose (UDP-Glc) added into keratinocyte cultures induced a specific, rapid induction of hyaluronan synthase 2 (HAS2), and an increase of hyaluronan synthesis.	Uridine Diphosphate Glucose	97-104	hyaluronan synthase 2	Homo sapiens	201-205
24847057-4	2014	Inhibition of JAK2, STAT3, or Gi-coupled receptors blocked the induction of HAS2 expression by UDP-Glc, the latter inhibitor suggesting that the signaling was triggered by the UDP-sugar receptor P2Y14.	Uridine Diphosphate Glucose	95-102	Janus kinase 2	Homo sapiens	14-18
24847057-4	2014	Inhibition of JAK2, STAT3, or Gi-coupled receptors blocked the induction of HAS2 expression by UDP-Glc, the latter inhibitor suggesting that the signaling was triggered by the UDP-sugar receptor P2Y14.	Uridine Diphosphate Glucose	95-102	signal transducer and activator of transcription 3	Homo sapiens	20-25
24847057-4	2014	Inhibition of JAK2, STAT3, or Gi-coupled receptors blocked the induction of HAS2 expression by UDP-Glc, the latter inhibitor suggesting that the signaling was triggered by the UDP-sugar receptor P2Y14.	Uridine Diphosphate Glucose	95-102	hyaluronan synthase 2	Homo sapiens	76-80
24847057-4	2014	Inhibition of JAK2, STAT3, or Gi-coupled receptors blocked the induction of HAS2 expression by UDP-Glc, the latter inhibitor suggesting that the signaling was triggered by the UDP-sugar receptor P2Y14.	Uridine Diphosphate Glucose	95-102	purinergic receptor P2Y14	Homo sapiens	195-200
24847057-7	2014	UDP-Glc also stimulated keratinocyte migration, proliferation, and IL-8 expression, supporting a notion that UDP-Glc signals for epidermal inflammation, enhanced hyaluronan synthesis as an integral part of it.	Uridine Diphosphate Glucose	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	67-71
24847057-7	2014	UDP-Glc also stimulated keratinocyte migration, proliferation, and IL-8 expression, supporting a notion that UDP-Glc signals for epidermal inflammation, enhanced hyaluronan synthesis as an integral part of it.	Uridine Diphosphate Glucose	109-116	C-X-C motif chemokine ligand 8	Homo sapiens	67-71
24558041-5	2014	These two lipids are synthesized by a single promiscuous glycosyltransferase encoded by the ORF atu2297, with UDP-glucose or UDP-glucuronic acid as sugar donors.	Uridine Diphosphate Glucose	110-121	glycosyl transferase family protein	Agrobacterium tumefaciens	57-76
24459244-8	2014	Molecular modeling identified key amino acids involved in the binding of UDP-GlcUA and UDP-Glc to UGT2B7.	Uridine Diphosphate Glucose	73-80	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	98-104
24459244-11	2014	Glucuronidation is the dominant metabolic pathway because the binding affinity of UDP-GlcUA to UGT2B7 is higher than that of UDP-Glc.	Uridine Diphosphate Glucose	82-89	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	95-101
24138077-1	2014	BACKGROUND AND PURPOSE: The P2Y14 receptor is the newest member of the P2Y receptor family; it is G(i/o) protein-coupled and is activated by UDP and selectively by UDP-glucose and MRS2690 (2-thiouridine-5"-diphosphoglucose) (7-10-fold more potent than UDP-glucose).	Uridine Diphosphate Glucose	164-175	purinergic receptor P2Y14	Homo sapiens	28-42
24138077-1	2014	BACKGROUND AND PURPOSE: The P2Y14 receptor is the newest member of the P2Y receptor family; it is G(i/o) protein-coupled and is activated by UDP and selectively by UDP-glucose and MRS2690 (2-thiouridine-5"-diphosphoglucose) (7-10-fold more potent than UDP-glucose).	Uridine Diphosphate Glucose	252-263	purinergic receptor P2Y14	Homo sapiens	28-42
24138077-11	2014	Removal of the endothelium and inhibition of endothelium-derived contractile agents (TxA2, PGF(2alpha) and endothelin-1) inhibited contractions to UDP glucose.	Uridine Diphosphate Glucose	147-158	endothelin 1	Homo sapiens	107-119
24138077-13	2014	UDP-glucose and MRS2690 increased MLC2 phosphorylation, which was blocked by PPTN.	Uridine Diphosphate Glucose	0-11	myosin light chain 2	Homo sapiens	34-38
24298902-5	2013	The sequencing of the coding region of the UFGT nuclear gene (UDP-glucose: flavonoid 3-0-glucosyltransferase, the key enzyme for the accumulation of anthocyanins in berry skins) enabled the discovery of discriminant SNPs (1/34 bp) and the reconstruction of 130 V. vinifera distinct genotypes.	Uridine Diphosphate Glucose	62-73	anthocyanidin 3-O-glucosyltransferase UFGT	Vitis vinifera	43-47
23801300-5	2013	The two enzymes used UDP-glucose and UDP-arabinose, respectively, and AtUGT78D2 was approximately 90-fold more efficient than AtUGT78D3 when judged by the k(cat)/K(m) value.	Uridine Diphosphate Glucose	21-32	UDP-glucosyl transferase 78D2	Arabidopsis thaliana	70-79
23801300-5	2013	The two enzymes used UDP-glucose and UDP-arabinose, respectively, and AtUGT78D2 was approximately 90-fold more efficient than AtUGT78D3 when judged by the k(cat)/K(m) value.	Uridine Diphosphate Glucose	21-32	UDP-glucosyl transferase 78D3	Arabidopsis thaliana	126-135
23732289-1	2013	UDP-galactose 4"-epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose, an important step in galactose catabolism.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	0-26
24086489-4	2013	When expressed in Escherichia coli as a recombinant protein with a maltose binding protein tag, UGT73C14 displayed enzymatic activity toward ABA and utilized UDP-glucose and UDP-galactose as the sugar donors.	Uridine Diphosphate Glucose	158-169	UDP-glycosyltransferase 73C6-like	Gossypium hirsutum	96-104
23732289-1	2013	UDP-galactose 4"-epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose, an important step in galactose catabolism.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	28-32
24048691-1	2013	The purinergic receptor P2Y, G protein coupled, 14 (P2Y14) receptor for UDP-glucose and other UDP-sugars has been implicated in the regulation of the stem cell compartment as well as neuroimmune function.	Uridine Diphosphate Glucose	72-83	purinergic receptor P2Y14	Homo sapiens	52-67
23864712-0	2013	UDP-glucose:glycoprotein glucosyltransferase (UGGT1) promotes substrate solubility in the endoplasmic reticulum.	Uridine Diphosphate Glucose	0-11	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	46-51
23864712-3	2013	UDP-glucose:glycoprotein glucosyltransferase (UGGT1) acts as a central component of glycoprotein ERQC, monoglucosylating deglucosylated N-glycans of incompletely folded glycoproteins and promoting subsequent reassociation with the lectin-like chaperones calreticulin and calnexin.	Uridine Diphosphate Glucose	0-11	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	46-51
24048691-4	2013	Extracellular addition of UDP-sugars such as UDP-glucose, UDP-galactose, UDP-glucuronic acid, and UDP-N-acetyl glucosamine promoted RANKL-induced osteoclastogenesis, while P2Y14 downregulation by RNA interference inhibited osteoclast formation.	Uridine Diphosphate Glucose	45-56	TNF superfamily member 11	Homo sapiens	132-137
23864712-3	2013	UDP-glucose:glycoprotein glucosyltransferase (UGGT1) acts as a central component of glycoprotein ERQC, monoglucosylating deglucosylated N-glycans of incompletely folded glycoproteins and promoting subsequent reassociation with the lectin-like chaperones calreticulin and calnexin.	Uridine Diphosphate Glucose	0-11	calreticulin	Homo sapiens	254-266
23864712-3	2013	UDP-glucose:glycoprotein glucosyltransferase (UGGT1) acts as a central component of glycoprotein ERQC, monoglucosylating deglucosylated N-glycans of incompletely folded glycoproteins and promoting subsequent reassociation with the lectin-like chaperones calreticulin and calnexin.	Uridine Diphosphate Glucose	0-11	calnexin	Homo sapiens	271-279
24048691-4	2013	Extracellular addition of UDP-sugars such as UDP-glucose, UDP-galactose, UDP-glucuronic acid, and UDP-N-acetyl glucosamine promoted RANKL-induced osteoclastogenesis, while P2Y14 downregulation by RNA interference inhibited osteoclast formation.	Uridine Diphosphate Glucose	45-56	purinergic receptor P2Y14	Homo sapiens	172-177
23863713-4	2013	In this study, we demonstrated that a nucleotide sugar, UDP-glucose, which is released into extracellular fluids in response to stress, mediates HSPC mobilization.	Uridine Diphosphate Glucose	56-67	proteasome 20S subunit alpha 7	Homo sapiens	145-149
23339688-2	2013	All healthy cells produce UDP-gal from uridine(5")diphospho(1)alpha-D-glucose (UDP-glc) by the action of UDP-galactose 4-epimerase (GalE).	Uridine Diphosphate Glucose	79-86	UDP-galactose-4-epimerase	Homo sapiens	105-130
23339688-2	2013	All healthy cells produce UDP-gal from uridine(5")diphospho(1)alpha-D-glucose (UDP-glc) by the action of UDP-galactose 4-epimerase (GalE).	Uridine Diphosphate Glucose	79-86	UDP-galactose-4-epimerase	Homo sapiens	132-136
23339688-11	2013	Structures of [GalE-NADH] in complex with UDP-glc show Lys153, Tyr149, and Ser124 in contact with NAD or glucosyl-C4(OH).	Uridine Diphosphate Glucose	42-49	UDP-galactose-4-epimerase	Homo sapiens	15-19
23828566-3	2013	Intriguingly, a putative P2Y14 receptor ligand, UDP-glucose, phenocopies the effect of P2Y14 deficiency.	Uridine Diphosphate Glucose	48-59	purinergic receptor P2Y14	Homo sapiens	25-39
23828566-3	2013	Intriguingly, a putative P2Y14 receptor ligand, UDP-glucose, phenocopies the effect of P2Y14 deficiency.	Uridine Diphosphate Glucose	48-59	purinergic receptor P2Y14	Homo sapiens	25-30
23640798-0	2013	UDP-glucose enhances outward K(+) currents necessary for cell differentiation and stimulates cell migration by activating the GPR17 receptor in oligodendrocyte precursors.	Uridine Diphosphate Glucose	0-11	G protein-coupled receptor 17	Homo sapiens	126-131
23640798-8	2013	The effect of UDP-glucose on K(+) currents is concentration-dependent, blocked by the GPR17 antagonists MRS2179 and cangrelor, and sensitive to the K(+) channel blocker tetraethyl-ammonium, which also inhibits oligodendrocyte maturation.	Uridine Diphosphate Glucose	14-25	G protein-coupled receptor 17	Homo sapiens	86-91
23863713-7	2013	Furthermore, co-administration of UDP-glucose and G-CSF led to greater HSPC mobilization than G-CSF alone.	Uridine Diphosphate Glucose	34-45	proteasome 20S subunit alpha 7	Homo sapiens	71-75
23863713-8	2013	Administration of the antioxidant agent NAC significantly reduced UDP-glucose-induced mobilization, coinciding with a reduction in RANKL and osteoclastogenesis.	Uridine Diphosphate Glucose	66-77	synuclein alpha	Homo sapiens	40-43
23863713-9	2013	These findings provide direct evidence demonstrating a potential role for UDP-glucose in HSPC mobilization and may provide an attractive strategy to improve the yield of stem cells in poor-mobilizing allogeneic or autologous donors.	Uridine Diphosphate Glucose	74-85	proteasome 20S subunit alpha 7	Homo sapiens	89-93
23181473-4	2013	GCS, a key enzyme of this pathway, neutralizes pro-apoptotic ceramide by transfer of a uridine diphosphate (UDP)-glucose.	Uridine Diphosphate Glucose	108-120	UDP-glucose ceramide glucosyltransferase	Homo sapiens	0-3
23592514-0	2013	A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.	Uridine Diphosphate Glucose	68-79	purinergic receptor P2Y14	Homo sapiens	44-58
23592514-7	2013	The concentration-effect curve of UDP-glucose for promoting inhibition of adenylyl cyclase in C6 glioma cells stably expressing the P2Y14-R was shifted to the right in a concentration-dependent manner by PPTN.	Uridine Diphosphate Glucose	34-45	purinergic receptor P2Y14	Homo sapiens	132-139
23592514-10	2013	UDP-glucose-promoted chemotaxis of differentiated HL-60 human promyelocytic leukemia cells was blocked by PPTN with a concentration dependence consistent with the KB determined with recombinant P2Y14-R.	Uridine Diphosphate Glucose	0-11	purinergic receptor P2Y14	Homo sapiens	194-201
23549747-5	2013	For the synthesis of quercetin 3-O-glucoside-7-O-rhamnoside, AtUGT78D2, which transfers glucose from UDP-glucose to the 3-hydroxyl group of quercetin, and AtUGT89C1, which transfers rhamnose from UDP-rhamnose to the 7-hydroxyl group of quercetin 3-O-glucoside, were transformed into E. coli.	Uridine Diphosphate Glucose	101-112	UDP-glucosyl transferase 78D2	Arabidopsis thaliana	61-70
23799153-6	2013	The Gne epimerases, as now defined after exclusion of those to be named GnaB or Gnu, are in the same clade as the GalE 4-epimerases for inter-conversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	156-167	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	Homo sapiens	4-7
23799153-6	2013	The Gne epimerases, as now defined after exclusion of those to be named GnaB or Gnu, are in the same clade as the GalE 4-epimerases for inter-conversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	169-176	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	Homo sapiens	4-7
23254995-1	2013	Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides.	Uridine Diphosphate Glucose	150-177	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	47-50
23254995-1	2013	Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides.	Uridine Diphosphate Glucose	179-190	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	47-50
23288840-6	2013	Both UDP-glucose and LTD(4) increased GPR17 internalization, although with different efficiency.	Uridine Diphosphate Glucose	5-16	G protein-coupled receptor 17	Homo sapiens	38-43
23363239-1	2013	Human UDP-alpha-d-glucose 6-dehydrogenase (hUGDH) forms a hexamer that catalyzes the NAD(+)-dependent oxidation of UDP-alpha-d-glucose (UDG) to produce UDP-alpha-d-glucuronic acid.	Uridine Diphosphate Glucose	6-25	UDP-glucose 6-dehydrogenase	Homo sapiens	43-48
23363239-1	2013	Human UDP-alpha-d-glucose 6-dehydrogenase (hUGDH) forms a hexamer that catalyzes the NAD(+)-dependent oxidation of UDP-alpha-d-glucose (UDG) to produce UDP-alpha-d-glucuronic acid.	Uridine Diphosphate Glucose	136-139	UDP-glucose 6-dehydrogenase	Homo sapiens	43-48
23363239-8	2013	We propose that the hysteresis in hUGDH is the consequence of a functional adaptation; by slowing the response of hUGDH to sudden increases in the flux of UDG, the other biochemical pathways that use this important metabolite (i.e., glycolysis) will have a competitive edge.	Uridine Diphosphate Glucose	155-158	UDP-glucose 6-dehydrogenase	Homo sapiens	34-39
23363239-8	2013	We propose that the hysteresis in hUGDH is the consequence of a functional adaptation; by slowing the response of hUGDH to sudden increases in the flux of UDG, the other biochemical pathways that use this important metabolite (i.e., glycolysis) will have a competitive edge.	Uridine Diphosphate Glucose	155-158	UDP-glucose 6-dehydrogenase	Homo sapiens	114-119
22872320-6	2013	Among Gi-coupled P2Y receptors, we found that an inhibition of P2Y(14) receptor, a receptor for nucleotide-sugars such as UDP-glucose, is responsible for the production of MMP-9 by pharmacological and molecular biochemical analysis.	Uridine Diphosphate Glucose	122-133	purinergic receptor P2Y14	Homo sapiens	63-79
23073611-6	2013	GlcCer, generated by glucosylceramide synthase (GCS) that transfers the glucose from UDP-glucose to ceramide, is an important glycosphingolipid metabolic intermediate.	Uridine Diphosphate Glucose	85-96	UDP-glucose ceramide glucosyltransferase	Homo sapiens	21-46
23073611-6	2013	GlcCer, generated by glucosylceramide synthase (GCS) that transfers the glucose from UDP-glucose to ceramide, is an important glycosphingolipid metabolic intermediate.	Uridine Diphosphate Glucose	85-96	UDP-glucose ceramide glucosyltransferase	Homo sapiens	48-51
22872320-6	2013	Among Gi-coupled P2Y receptors, we found that an inhibition of P2Y(14) receptor, a receptor for nucleotide-sugars such as UDP-glucose, is responsible for the production of MMP-9 by pharmacological and molecular biochemical analysis.	Uridine Diphosphate Glucose	122-133	matrix metallopeptidase 9	Homo sapiens	172-177
22991416-10	2012	The selective P2Y(6) receptor agonist 3-(2-oxo-2-phenylethyl)-UDP (PSB 0474) evoked concentration-dependent contractions and was approximately three times more potent than UDP, but the P2Y(14) agonist UDP-glucose had no effect.	Uridine Diphosphate Glucose	201-212	pyrimidinergic receptor P2Y6	Rattus norvegicus	14-20
23159939-2	2012	In the present system, UDP, a product inhibitor of PSPGs, was removed from the reaction mixture and used for regeneration of UDP-glucose by AtSUS1.	Uridine Diphosphate Glucose	125-136	sucrose synthase 1	Arabidopsis thaliana	140-146
23105111-1	2012	The glycosphingolipid biosynthesis is initiated by monoglycosylation of ceramides, the action of which is catalyzed either by UDP-glucose:ceramide glucosyltransferase or by UDP-galactose:ceramide galactosyltransferase (CGalT).	Uridine Diphosphate Glucose	126-137	UDP glycosyltransferase 8	Homo sapiens	219-224
23106432-1	2012	Human UDP-alpha-D-glucose dehydrogenase (hUGDH) catalyzes the NAD(+)-dependent oxidation of UDP-alpha-D-glucose (UDG) to produce UDP-alpha-D-glucuronic acid.	Uridine Diphosphate Glucose	6-25	UDP-glucose 6-dehydrogenase	Homo sapiens	41-46
23022311-1	2012	The therapeutic effects of UDP-glucose (UDPG), an endogenous agonist of GPR17 that may promote the self-repair of white matter, glial cell line-derived neurotrophic factor (GDNF), a neurotrophic factor correlated with the growth and survival of nerve cells, and memantine, an antagonist of NMDA receptors, were evaluated for functional improvement of neonatal rats with experimental periventricular leukomalacia (PVL).	Uridine Diphosphate Glucose	27-38	G protein-coupled receptor 17	Rattus norvegicus	72-77
23022311-1	2012	The therapeutic effects of UDP-glucose (UDPG), an endogenous agonist of GPR17 that may promote the self-repair of white matter, glial cell line-derived neurotrophic factor (GDNF), a neurotrophic factor correlated with the growth and survival of nerve cells, and memantine, an antagonist of NMDA receptors, were evaluated for functional improvement of neonatal rats with experimental periventricular leukomalacia (PVL).	Uridine Diphosphate Glucose	27-38	glial cell derived neurotrophic factor	Rattus norvegicus	128-171
23106432-1	2012	Human UDP-alpha-D-glucose dehydrogenase (hUGDH) catalyzes the NAD(+)-dependent oxidation of UDP-alpha-D-glucose (UDG) to produce UDP-alpha-D-glucuronic acid.	Uridine Diphosphate Glucose	113-116	UDP-glucose 6-dehydrogenase	Homo sapiens	41-46
23072384-6	2012	The production of quercetin 3-O-rhamnoside could be increased by up to 160% by co-expressing AtUGT78D1 and rhamnose synthase gene 2 (RHM2), which catalyzes the conversion of UDP-glucose into UDP-rhamnose.	Uridine Diphosphate Glucose	174-185	UDP-glucosyl transferase 78D1	Arabidopsis thaliana	93-131
22933714-0	2012	Arabidopsis thaliana AtUTr7 encodes a golgi-localized UDP-glucose/UDP-galactose transporter that affects lateral root emergence.	Uridine Diphosphate Glucose	54-65	UDP-N-acetylglucosamine (UAA) transporter family	Arabidopsis thaliana	21-27
22933714-8	2012	Additionally, the results of an in vitro nucleotide sugar transport assay carried out with a tobacco and a yeast expression system suggest that AtUTr7 is capable of transferring UDP-Gal and UDP-Glc, but not a range of other UDP- and GDP-sugars, into the Golgi lumen.	Uridine Diphosphate Glucose	190-197	UDP-N-acetylglucosamine (UAA) transporter family	Arabidopsis thaliana	144-150
22762304-2	2012	In this study, we report the functional heterologous expression of Drosophila melanogaster TPS, the gene identification, full length cDNA cloning and functional expression of cat flea (Ctenocephalides felis) TPS, and the Michaelis-Menten constants for their specific substrates glucose-6-phosphate and uridinediphosphate-glucose.	Uridine Diphosphate Glucose	302-328	Trehalose-6-phosphate synthase 1	Drosophila melanogaster	91-94
22778393-1	2012	GPR105, a G protein-coupled receptor for UDP-glucose, is highly expressed in several human tissues and participates in the innate immune response.	Uridine Diphosphate Glucose	41-52	purinergic receptor P2Y14	Homo sapiens	0-6
22621930-2	2012	Rather, UGT3A1 uses GlcNAc as preferred sugar donor and UGT3A2 uses UDP-Glc.	Uridine Diphosphate Glucose	68-75	UDP glycosyltransferase family 3 member A2	Homo sapiens	56-62
22673622-4	2012	We also demonstrate that UDP-glucose promotes rapid, robust, and concentration-dependent activation of RhoA in these cells.	Uridine Diphosphate Glucose	25-36	ras homolog family member A	Homo sapiens	103-107
22673622-9	2012	UDP-glucose-promoted RhoA activation also was accompanied by enhanced cell migration in differentiated HL60 cells, and these responses were blocked by Rho kinase inhibitors.	Uridine Diphosphate Glucose	0-11	ras homolog family member A	Homo sapiens	21-25
22673622-10	2012	These results support the notion that UDP-glucose is a stable and potent proinflammatory mediator that promotes P2Y(14)-R-mediated neutrophil motility via Rho/Rho kinase activation.	Uridine Diphosphate Glucose	38-49	purinergic receptor P2Y14	Homo sapiens	112-121
22525098-0	2012	Catalytic mechanism of human UDP-glucose 6-dehydrogenase: in situ proton NMR studies reveal that the C-5 hydrogen of UDP-glucose is not exchanged with bulk water during the enzymatic reaction.	Uridine Diphosphate Glucose	29-40	complement C5	Homo sapiens	101-104
22525098-1	2012	Human UDP-glucose 6-dehydrogenase (hUGDH) catalyzes the biosynthetic oxidation of UDP-glucose into UDP-glucuronic acid.	Uridine Diphosphate Glucose	6-17	UDP-glucose 6-dehydrogenase	Homo sapiens	35-40
22621930-5	2012	Conversely, a phenylalanine (Phe-391) in UGT3A2 favors UDP-Glc use.	Uridine Diphosphate Glucose	55-62	UDP glycosyltransferase family 3 member A2	Homo sapiens	41-47
22621930-6	2012	Mutation of Asn-391 to Phe in UGT3A1 enhances its ability to utilize UDP-Glc and completely inhibits its ability to use UDP-GlcNAc.	Uridine Diphosphate Glucose	69-76	UDP glycosyltransferase family 3 member A1	Homo sapiens	30-36
22159735-2	2012	The Arabidopsis enzyme AtUGT78D2 prefers UDP-glucose as a sugar donor and quercetin as a sugar acceptor.	Uridine Diphosphate Glucose	41-52	UDP-glucosyl transferase 78D2	Arabidopsis thaliana	23-32
22483615-1	2012	Classic galactosemia is an autosomal recessive disorder of carbohydrate metabolism, due to a severe deficiency of the enzyme, galactose-1-phosphate uridyltransferase (GALT), that catalyzes the conversion of galactose-1-phosphate and uridine diphosphate glucose (UDPglucose) to uridine diphosphate galactose (UDPgalactose) and glucose-1-phosphate.	Uridine Diphosphate Glucose	233-260	galactose-1-phosphate uridylyltransferase	Homo sapiens	126-165
22483615-1	2012	Classic galactosemia is an autosomal recessive disorder of carbohydrate metabolism, due to a severe deficiency of the enzyme, galactose-1-phosphate uridyltransferase (GALT), that catalyzes the conversion of galactose-1-phosphate and uridine diphosphate glucose (UDPglucose) to uridine diphosphate galactose (UDPgalactose) and glucose-1-phosphate.	Uridine Diphosphate Glucose	233-260	galactose-1-phosphate uridylyltransferase	Homo sapiens	167-171
22483615-1	2012	Classic galactosemia is an autosomal recessive disorder of carbohydrate metabolism, due to a severe deficiency of the enzyme, galactose-1-phosphate uridyltransferase (GALT), that catalyzes the conversion of galactose-1-phosphate and uridine diphosphate glucose (UDPglucose) to uridine diphosphate galactose (UDPgalactose) and glucose-1-phosphate.	Uridine Diphosphate Glucose	262-272	galactose-1-phosphate uridylyltransferase	Homo sapiens	126-165
22483615-1	2012	Classic galactosemia is an autosomal recessive disorder of carbohydrate metabolism, due to a severe deficiency of the enzyme, galactose-1-phosphate uridyltransferase (GALT), that catalyzes the conversion of galactose-1-phosphate and uridine diphosphate glucose (UDPglucose) to uridine diphosphate galactose (UDPgalactose) and glucose-1-phosphate.	Uridine Diphosphate Glucose	262-272	galactose-1-phosphate uridylyltransferase	Homo sapiens	167-171
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	103-110	glycogen synthase 1	Rattus norvegicus	19-23
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	103-110	glycogen synthase 2	Rattus norvegicus	27-31
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	103-110	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	35-39
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	112-123	glycogen synthase 1	Rattus norvegicus	19-23
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	112-123	glycogen synthase 2	Rattus norvegicus	27-31
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	112-123	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	35-39
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	211-218	glycogen synthase 1	Rattus norvegicus	19-23
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	211-218	glycogen synthase 2	Rattus norvegicus	27-31
22233421-3	2012	Phosphorylation of GYS1 or GYS2 by AMPK led to enzyme inactivation by decreasing the affinity for both UDP-Glc (UDP-glucose) [assayed in the absence of Glc-6-P (glucose-6-phosphate)] and Glc-6-P (assayed at low UDP-Glc concentrations).	Uridine Diphosphate Glucose	211-218	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	35-39
21830156-5	2012	Application of ESI-MS/MS to seed samples from wild-type Arabidopsis and a mutant deficient in two UDP-glucose:sterol glucosyltransferases, UGT80A2 and UGT80B1, revealed new details on the composition of sitosteryl, campesteryl and stigmasteryl glucosides and ASG.	Uridine Diphosphate Glucose	98-109	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	139-146
21830156-5	2012	Application of ESI-MS/MS to seed samples from wild-type Arabidopsis and a mutant deficient in two UDP-glucose:sterol glucosyltransferases, UGT80A2 and UGT80B1, revealed new details on the composition of sitosteryl, campesteryl and stigmasteryl glucosides and ASG.	Uridine Diphosphate Glucose	98-109	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	151-158
22654673-1	2012	In both humans and Drosophila melanogaster, UDP-galactose 4"-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc).	Uridine Diphosphate Glucose	156-167	UDP-galactose 4'-epimerase	Drosophila melanogaster	44-70
22654673-1	2012	In both humans and Drosophila melanogaster, UDP-galactose 4"-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc).	Uridine Diphosphate Glucose	156-167	UDP-galactose 4'-epimerase	Drosophila melanogaster	72-76
22654673-1	2012	In both humans and Drosophila melanogaster, UDP-galactose 4"-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc).	Uridine Diphosphate Glucose	169-176	UDP-galactose 4'-epimerase	Drosophila melanogaster	44-70
22654673-1	2012	In both humans and Drosophila melanogaster, UDP-galactose 4"-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc).	Uridine Diphosphate Glucose	169-176	UDP-galactose 4'-epimerase	Drosophila melanogaster	72-76
21757635-5	2011	The subcellular location of the Sus isoforms is determined, and it is proposed that cell wall-localized SusC may provide UDP-glucose for cellulose and callose synthesis from extracellular sugars.	Uridine Diphosphate Glucose	121-132	sucrose synthase-like	Gossypium hirsutum	104-108
21949356-4	2011	Here we show that both mouse and human Rumi, but not KDELC1 or KDELC2, catalyze transfer of glucose from UDP-glucose to an EGF repeat from human factor VII.	Uridine Diphosphate Glucose	105-116	protein O-glucosyltransferase 1	Homo sapiens	39-43
21949356-11	2011	Altogether, our data establish dual substrate specificity for the glycosyltransferase Rumi and provide evidence that amino acid sequences of the recipient EGF repeat significantly influence which donor substrate (UDP-glucose or UDP-Xyl) is used.	Uridine Diphosphate Glucose	213-224	rumi	Drosophila melanogaster	86-90
21773791-8	2011	During the second half of embryogenesis utilization of uridine for UTP + UDPglucose (UDPG) synthesis increased in the embryos over-expressing BnSTM, and this coincided with a better post-germination performance.	Uridine Diphosphate Glucose	85-89	homeobox protein SHOOT MERISTEMLESS	Brassica napus	142-147
21835921-5	2011	GT MG517 transfers glucosyl and galactosyl residues from UDP-Glc and UDP-Gal to dioleoylglycerol (DOG) acceptor to form the corresponding beta-glycosyl-DOG, which then acts as acceptor to give beta-diglycosyl-DOG products.	Uridine Diphosphate Glucose	57-64	protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2	Canis lupus familiaris	0-2
21865170-5	2011	The x-ray crystal structure of sucrose synthase isoform 1 from Arabidopsis thaliana (AtSus1) has been determined as a complex with UDP-glucose and as a complex with UDP and fructose, at 2.8- and 2.85-A resolutions, respectively.	Uridine Diphosphate Glucose	131-142	sucrose synthase 1	Arabidopsis thaliana	85-91
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	ATP binding cassette subfamily B member 1	Homo sapiens	35-39
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	ATP binding cassette subfamily B member 1	Homo sapiens	40-54
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	ATP binding cassette subfamily B member 1	Homo sapiens	56-60
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	phosphoglycolate phosphatase	Homo sapiens	61-65
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	UDP-glucose ceramide glucosyltransferase	Homo sapiens	68-93
21538359-1	2011	BACKGROUND AND OBJECTIVES: Besides MDR1/P-glycoprotein (MDR1/P-gp), glucosylceramide synthase (GCS), an enzyme, which transfers UDP-glucose to ceramide to form glucosylceramide was also related with multidrug resistance (MDR) in breast cancer.	Uridine Diphosphate Glucose	128-139	UDP-glucose ceramide glucosyltransferase	Homo sapiens	95-98
21768092-1	2011	The 15-kDa selenoprotein (Sep15) is a thioredoxin-like, endoplasmic reticulum-resident protein involved in the quality control of glycoprotein folding through its interaction with UDP-glucose:glycoprotein glucosyltransferase.	Uridine Diphosphate Glucose	180-191	selenoprotein F	Mus musculus	4-24
21768092-1	2011	The 15-kDa selenoprotein (Sep15) is a thioredoxin-like, endoplasmic reticulum-resident protein involved in the quality control of glycoprotein folding through its interaction with UDP-glucose:glycoprotein glucosyltransferase.	Uridine Diphosphate Glucose	180-191	selenoprotein F	Mus musculus	26-31
21793161-4	2011	The mechanism of GALT was established through classical enzymological methods to be a substituted enzyme in which the reaction with UDP-glucose results in the formation of a covalent, UMP-histidine adduct in the active site.	Uridine Diphosphate Glucose	132-143	galactose-1-phosphate uridylyltransferase	Homo sapiens	17-21
21531793-1	2011	G protein-coupled receptor (GPR) 17 is a P2Y-like receptor that responds to both uracil nucleotides (as UDP-glucose) and cysteinyl-leukotrienes (cysLTs, as LTD(4)).	Uridine Diphosphate Glucose	104-115	G protein-coupled receptor 17	Homo sapiens	41-58
21602353-5	2011	UDP-glucose dehydrogenase (UGD) is responsible for the NAD-dependent 2-fold oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronic acid (UDP-GlcA), which is a key step in cepacian biosynthesis.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-30
21602353-5	2011	UDP-glucose dehydrogenase (UGD) is responsible for the NAD-dependent 2-fold oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronic acid (UDP-GlcA), which is a key step in cepacian biosynthesis.	Uridine Diphosphate Glucose	102-109	UDP-glucose 6-dehydrogenase	Homo sapiens	0-25
21602353-5	2011	UDP-glucose dehydrogenase (UGD) is responsible for the NAD-dependent 2-fold oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronic acid (UDP-GlcA), which is a key step in cepacian biosynthesis.	Uridine Diphosphate Glucose	102-109	UDP-glucose 6-dehydrogenase	Homo sapiens	27-30
21531793-6	2011	Both UDP-glucose and LTD(4) induced a time- and concentration-dependent GPR17 loss of response (homologous desensitization) with similar kinetics.	Uridine Diphosphate Glucose	5-16	G protein-coupled receptor 17	Homo sapiens	72-77
21531793-9	2011	Finally, activation of GPR17 by UDP-glucose (but not vice versa) induced a partial heterologous desensitization of LTD(4)-mediated responses, suggesting that nucleotides have a hierarchy in producing desensitizing signals.	Uridine Diphosphate Glucose	32-43	G protein-coupled receptor 17	Homo sapiens	23-28
21558268-7	2011	We investigated the substrate specificity of TagE using a wide variety of acceptor substrates and found that the enzyme had a strong kinetic preference for the transfer of glucose from UDP-glucose to glycerol phosphate in polymeric form.	Uridine Diphosphate Glucose	185-196	UDP-glucose:polyglycerol phosphate alpha-glucosyltransferase	Bacillus subtilis subsp. subtilis str. 168	45-49
21502315-3	2011	Human UDP-glucose 6-dehydrogenase (hUGDH) catalyzes, in two NAD(+)-dependent steps without release of intermediate aldehyde, the biosynthetic oxidation of UDP-glucose (UDP-Glc) to UDP-GlcUA.	Uridine Diphosphate Glucose	6-17	UDP-glucose 6-dehydrogenase	Homo sapiens	35-40
21502315-3	2011	Human UDP-glucose 6-dehydrogenase (hUGDH) catalyzes, in two NAD(+)-dependent steps without release of intermediate aldehyde, the biosynthetic oxidation of UDP-glucose (UDP-Glc) to UDP-GlcUA.	Uridine Diphosphate Glucose	168-175	UDP-glucose 6-dehydrogenase	Homo sapiens	6-33
21502315-3	2011	Human UDP-glucose 6-dehydrogenase (hUGDH) catalyzes, in two NAD(+)-dependent steps without release of intermediate aldehyde, the biosynthetic oxidation of UDP-glucose (UDP-Glc) to UDP-GlcUA.	Uridine Diphosphate Glucose	168-175	UDP-glucose 6-dehydrogenase	Homo sapiens	35-40
21502315-4	2011	Here, we present a structural characterization of the hUGDH reaction coordinate using crystal structures of the apoenzyme and ternary complexes of the enzyme bound with UDP-Glc/NADH and UDP-GlcUA/NAD(+).	Uridine Diphosphate Glucose	169-176	UDP-glucose 6-dehydrogenase	Homo sapiens	54-59
21383180-9	2011	Collectively, the data indicate that CRT in the PLC enhances weak tapasin/class I interactions in a manner that is glycan-dependent and regulated by UDP-glucose:glycoprotein glucosyltransferase 1.	Uridine Diphosphate Glucose	149-160	Calreticulin	Drosophila melanogaster	37-40
21394467-5	2011	The alternative pathway to UDP-glucuronic acid via UDP-glucose is upregulated in the miox1/2/4/5-mutant as a compensatory mechanism.	Uridine Diphosphate Glucose	51-62	myo-inositol oxygenase 1	Arabidopsis thaliana	85-96
21325339-1	2011	Ceramide glucosyltransferase (Ugcg) [uridine diphosphate (UDP)-glucose:N-acylsphingosine D-glucosyltransferase or UDP-glucose ceramide glucosyltransferase (GlcT): EC 2.4.1.80] catalyzes formation of glucosylceramide (GlcCer) from ceramide and UDP-glucose.	Uridine Diphosphate Glucose	114-125	UDP-glucose ceramide glucosyltransferase	Mus musculus	30-34
21833323-6	2011	The enzymes use UDP-glucose as a donor substrate and modify eukaryotic elongation factor eEF1A at serine-53.	Uridine Diphosphate Glucose	16-27	eukaryotic translation elongation factor 1 alpha 1	Homo sapiens	89-94
21821827-2	2011	UDP-Glc has been previously shown to activate human P2Y14, whereas UDP was unable to activate the receptor.	Uridine Diphosphate Glucose	0-7	purinergic receptor P2Y14	Homo sapiens	52-57
21821827-7	2011	UDP-Glc, UMP, and UDP dose dependently inhibited [(3)H]UDP binding in the binding assay, and saturation analysis revealed that UDP bound P2Y14 with a K(D) = 10 nM and a B(max) = 110 pmol/mg.	Uridine Diphosphate Glucose	0-7	purinergic receptor P2Y14	Homo sapiens	137-142
21081508-7	2011	As examples, we first assayed Clostridium difficile toxin B, a protein O-glucosyltransferase that specifically monoglucosylates and inactivates Rho family small GTPases; we then showed that human KTELC1, a homolog of Rumi from Drosophila, was able to hydrolyze UDP-Glc; and finally, we measured the kinetic parameters of human sialyltransferase ST6GAL1.	Uridine Diphosphate Glucose	261-268	protein O-glucosyltransferase 1	Homo sapiens	196-202
21324179-9	2011	PDK4 may act as a glycogen sensor in muscle, UGDH may compete for glycogen synthesis by using UDP-glucose for glucoronidation, and PRKAB1, PRKAG2, and PHKD may impact on glycogen turnover in muscle, through AMP-activated signalling pathways.	Uridine Diphosphate Glucose	94-105	UDP-glucose 6-dehydrogenase	Gallus gallus	45-49
21088224-7	2011	However, in contrast to UGT3A1, UGT3A2 uses both UDP glucose and UDP xylose but not UDP N-acetylglucosamine to glycosidate a broad range of substrates including 4-methylumbelliferone, 1-hydroxypyrene, bioflavones, and estrogens.	Uridine Diphosphate Glucose	49-60	UDP glycosyltransferase family 3 member A2	Homo sapiens	32-38
20435647-1	2010	UDP-glucose pyrophosphorylase (UGPase) is an important enzyme in the metabolism of UDP-glucose, a precursor for the synthesis of carbohydrate cell wall components, such as cellulose and callose.	Uridine Diphosphate Glucose	0-11	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	31-37
20691680-1	2010	UDP-glucose dehydrogenase (UGDH) catalyzes oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor of hyaluronic acid (HA) and other glycosaminoglycans (GAGs) in extracellular matrix.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
20863317-1	2010	Biosynthesis of the glycosaminoglycan precursor UDP-alpha-D-glucuronic acid occurs through a 2-fold oxidation of UDP-alpha-D-glucose that is catalysed by UGDH (UDP-alpha-D-glucose 6-dehydrogenase).	Uridine Diphosphate Glucose	113-132	UDP-glucose 6-dehydrogenase	Homo sapiens	154-158
20863317-1	2010	Biosynthesis of the glycosaminoglycan precursor UDP-alpha-D-glucuronic acid occurs through a 2-fold oxidation of UDP-alpha-D-glucose that is catalysed by UGDH (UDP-alpha-D-glucose 6-dehydrogenase).	Uridine Diphosphate Glucose	113-132	UDP-glucose 6-dehydrogenase	Homo sapiens	160-195
21637578-1	2010	UDP-glucose dehydrogenase (UGDH) catalyzes the oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronate (UDP-GlcA), a key sugar nucleotide involved in the biosynthesis of plant cell wall polysaccharides.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase 1	Eucalyptus grandis	27-31
21637578-1	2010	UDP-glucose dehydrogenase (UGDH) catalyzes the oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronate (UDP-GlcA), a key sugar nucleotide involved in the biosynthesis of plant cell wall polysaccharides.	Uridine Diphosphate Glucose	73-80	UDP-glucose 6-dehydrogenase 1	Eucalyptus grandis	0-25
21637578-1	2010	UDP-glucose dehydrogenase (UGDH) catalyzes the oxidation of UDP-glucose (UDP-Glc) to UDP-glucuronate (UDP-GlcA), a key sugar nucleotide involved in the biosynthesis of plant cell wall polysaccharides.	Uridine Diphosphate Glucose	73-80	UDP-glucose 6-dehydrogenase 1	Eucalyptus grandis	27-31
21637578-4	2010	The recombinant protein expressed in Escherichia coli catalyzed the conversion of UDP-Glc to UDP-GlcA, confirming that the cloned cDNA encodes UGDH.	Uridine Diphosphate Glucose	82-89	UDP-glucose 6-dehydrogenase 1	Eucalyptus grandis	143-147
21984906-1	2011	BACKGROUND: UDP-glucose dehydrogenase (UGDH) is the sole enzyme that catalyzes the conversion of UDP-glucose to UDP-glucuronic acid.	Uridine Diphosphate Glucose	12-23	UDP-glucose 6-dehydrogenase	Homo sapiens	39-43
21984906-6	2011	Here, we have solved an alternate crystal structure of human UGDH (hUGDH) in complex with UDP-glucose at 2.8 A resolution.	Uridine Diphosphate Glucose	90-101	UDP-glucose 6-dehydrogenase	Homo sapiens	61-65
21984906-6	2011	Here, we have solved an alternate crystal structure of human UGDH (hUGDH) in complex with UDP-glucose at 2.8 A resolution.	Uridine Diphosphate Glucose	90-101	UDP-glucose 6-dehydrogenase	Homo sapiens	67-72
20519568-1	2010	UDP-galactose 4" epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose in the final step of the Leloir pathway; human GALE (hGALE) also interconverts UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	0-26
20519568-1	2010	UDP-galactose 4" epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose in the final step of the Leloir pathway; human GALE (hGALE) also interconverts UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	28-32
20519568-1	2010	UDP-galactose 4" epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose in the final step of the Leloir pathway; human GALE (hGALE) also interconverts UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	144-148
20519568-1	2010	UDP-galactose 4" epimerase (GALE) catalyzes the interconversion of UDP-galactose and UDP-glucose in the final step of the Leloir pathway; human GALE (hGALE) also interconverts UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	85-96	UDP-galactose-4-epimerase	Homo sapiens	150-155
22563139-2	2010	This glucosylceramide analogue acts as an inhibitor of glucosylceramide synthase, a Golgi complex enzyme that catalyzes the formation of glucosylceramide from ceramide and UDP-glucose and is the first step in the formation of glucocerebroside-based glycosphingolipids.	Uridine Diphosphate Glucose	172-183	UDP-glucose ceramide glucosyltransferase	Homo sapiens	55-80
20359473-1	2010	BACKGROUND: Galactose-1-phosphate:uridyltransferase (GALT) catalyses the conversion of galactose-1-phosphate (Gal-1-P) and UDP-glucose (UDP-Glc) into glucose-6-phosphate and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	123-134	galactose-1-phosphate uridylyltransferase	Homo sapiens	12-51
20359473-1	2010	BACKGROUND: Galactose-1-phosphate:uridyltransferase (GALT) catalyses the conversion of galactose-1-phosphate (Gal-1-P) and UDP-glucose (UDP-Glc) into glucose-6-phosphate and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	123-134	galactose-1-phosphate uridylyltransferase	Homo sapiens	53-57
20359473-1	2010	BACKGROUND: Galactose-1-phosphate:uridyltransferase (GALT) catalyses the conversion of galactose-1-phosphate (Gal-1-P) and UDP-glucose (UDP-Glc) into glucose-6-phosphate and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	136-143	galactose-1-phosphate uridylyltransferase	Homo sapiens	12-51
20359473-1	2010	BACKGROUND: Galactose-1-phosphate:uridyltransferase (GALT) catalyses the conversion of galactose-1-phosphate (Gal-1-P) and UDP-glucose (UDP-Glc) into glucose-6-phosphate and UDP-galactose (UDP-Gal).	Uridine Diphosphate Glucose	136-143	galactose-1-phosphate uridylyltransferase	Homo sapiens	53-57
20359473-5	2010	METHODS: GALT activity was measured in erythrocyte lysates using optimal concentrations of the substrates galactose-1-phosphate and UDP-Glc.	Uridine Diphosphate Glucose	132-139	galactose-1-phosphate uridylyltransferase	Homo sapiens	9-13
20435647-11	2010	In contrast, an application of external UDP-glucose recovered male fertility in the double mutant, suggesting that control of UGPase in carbohydrate metabolism is different in the vegetative phase as compared with the reproductive phase in A. thaliana.	Uridine Diphosphate Glucose	40-51	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	126-132
20299182-12	2010	The three genes most up-regulated by TSP-1 in a normoglycemic environment were uridine 5"-diphosphoglucose (UDP-glucose) dehydrogenase (UGDH, 127%), transforming growth factor beta-2 (TGFbeta2, 116%), and hyaluronan synthase 2 (HAS2, 113%).	Uridine Diphosphate Glucose	79-106	thrombospondin 1	Homo sapiens	37-42
20299182-12	2010	The three genes most up-regulated by TSP-1 in a normoglycemic environment were uridine 5"-diphosphoglucose (UDP-glucose) dehydrogenase (UGDH, 127%), transforming growth factor beta-2 (TGFbeta2, 116%), and hyaluronan synthase 2 (HAS2, 113%).	Uridine Diphosphate Glucose	79-106	UDP-glucose 6-dehydrogenase	Homo sapiens	108-134
20056144-1	2010	The P2Y-like receptor GPR17 has been reported to respond to both uracil nucleotides and cysteinyl-leukotrienes (cysLTs), such as UDP-glucose and LTD(4).	Uridine Diphosphate Glucose	129-140	G protein-coupled receptor 17	Rattus norvegicus	22-27
20056144-6	2010	Both UDP-glucose and LTD(4), agonists at the nucleotide and cysLT GPR17 binding sites, respectively, induced a significant pro-survival effect on PC12 cells after priming with NGF.	Uridine Diphosphate Glucose	5-16	G protein-coupled receptor 17	Rattus norvegicus	66-71
20130677-5	2010	Furthermore, in humans, Rvb1 and Rvb2 have been identified in the URI prefoldin-like complex.	Uridine Diphosphate Glucose	66-69	RuvB like AAA ATPase 1	Homo sapiens	24-28
20030628-6	2010	Furthermore, we showed that two further L. pneumophila glycosyltransferases possessed the conserved UDP-glucose-binding sites and EF1A-binding grooves, and are, like LpGT, translocated into the macrophage through the Icm/Dot (intracellular multiplication/defect in organelle trafficking) system.	Uridine Diphosphate Glucose	100-111	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	130-134
20130677-5	2010	Furthermore, in humans, Rvb1 and Rvb2 have been identified in the URI prefoldin-like complex.	Uridine Diphosphate Glucose	66-69	RuvB like AAA ATPase 2	Homo sapiens	33-37
19759354-1	2009	The P2Y14 receptor was initially identified as a G protein-coupled receptor activated by UDP-glucose and other nucleotide sugars.	Uridine Diphosphate Glucose	89-100	purinergic receptor P2Y14	Homo sapiens	4-18
19906043-0	2010	The nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the endoplasmic reticulum, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana.	Uridine Diphosphate Glucose	90-101	UDP-galactose transporter 1	Arabidopsis thaliana	34-40
19906043-0	2010	The nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the endoplasmic reticulum, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana.	Uridine Diphosphate Glucose	90-101	UDP-galactose transporter 3	Arabidopsis thaliana	45-51
19906043-2	2010	Here we show that AtUTr3 is involved in the transport of UDP-glucose and is located at the ER but also at the Golgi.	Uridine Diphosphate Glucose	57-68	UDP-galactose transporter 3	Arabidopsis thaliana	18-24
19906043-4	2010	Biochemical analysis in both AtUTr1 and AtUTr3 mutants indicates that uptake of UDP-glucose into the ER is mostly driven by these two transporters.	Uridine Diphosphate Glucose	80-91	UDP-galactose transporter 1	Arabidopsis thaliana	29-35
19906043-4	2010	Biochemical analysis in both AtUTr1 and AtUTr3 mutants indicates that uptake of UDP-glucose into the ER is mostly driven by these two transporters.	Uridine Diphosphate Glucose	80-91	UDP-galactose transporter 3	Arabidopsis thaliana	40-46
19906043-5	2010	Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated.	Uridine Diphosphate Glucose	216-227	UDP-galactose transporter 3	Arabidopsis thaliana	33-39
19906043-5	2010	Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated.	Uridine Diphosphate Glucose	216-227	UDP-galactose transporter 1	Arabidopsis thaliana	143-149
19906043-5	2010	Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated.	Uridine Diphosphate Glucose	216-227	UDP-galactose transporter 1	Arabidopsis thaliana	172-178
19906043-5	2010	Interestingly, the expression of AtUTr3 is induced by stimuli that trigger the unfolded protein response (UPR), a phenomenon also observed for AtUTr1, suggesting that both AtUTr1 and AtUTr3 are involved in supplying UDP-glucose into the ER lumen when misfolded proteins are accumulated.	Uridine Diphosphate Glucose	216-227	UDP-galactose transporter 3	Arabidopsis thaliana	183-189
19906043-9	2010	These results show that the nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the ER, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana.	Uridine Diphosphate Glucose	114-125	UDP-galactose transporter 1	Arabidopsis thaliana	58-64
19906043-9	2010	These results show that the nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the ER, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana.	Uridine Diphosphate Glucose	114-125	UDP-galactose transporter 3	Arabidopsis thaliana	69-75
19676054-1	2010	Uridine diphosphate (UDP)-glucose dehydrogenase (UGDH) catalyzes the oxidation of UDP-glucose to yield UDP-glucuronic acid, a precursor for synthesis of glycosaminoglycans and proteoglycans that promote aggressive prostate cancer (PC) progression.	Uridine Diphosphate Glucose	82-93	UDP-glucose 6-dehydrogenase	Homo sapiens	49-53
19902968-0	2010	Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5"-diphosphoglucose and its replacement with alkyl and aryl groups.	Uridine Diphosphate Glucose	68-95	purinergic receptor P2Y14	Homo sapiens	6-22
19902968-1	2010	Uridine-5"-diphosphoglucose (UDPG) activates the P2Y(14) receptor, a neuroimmune system GPCR.	Uridine Diphosphate Glucose	0-27	purinergic receptor P2Y14	Homo sapiens	49-65
19902968-1	2010	Uridine-5"-diphosphoglucose (UDPG) activates the P2Y(14) receptor, a neuroimmune system GPCR.	Uridine Diphosphate Glucose	0-27	G protein-coupled receptor 166 pseudogene	Homo sapiens	88-92
19699703-1	2010	The human P2Y(14) receptor is potently activated by UDP-glucose (UDP-Glc), UDP-galactose (UDP-Gal), UDP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.	Uridine Diphosphate Glucose	52-63	purinergic receptor P2Y14	Homo sapiens	10-26
19699703-1	2010	The human P2Y(14) receptor is potently activated by UDP-glucose (UDP-Glc), UDP-galactose (UDP-Gal), UDP-N-acetylglucosamine (UDP-GlcNAc), and UDP-glucuronic acid.	Uridine Diphosphate Glucose	65-72	purinergic receptor P2Y14	Homo sapiens	10-26
19759354-5	2009	The apparent efficacies of UDP and UDP-glucose were similar, and the EC50 values (74, 33, and 29 nM) for UDP-dependent activation of the P2Y14 receptor in HEK293, CHO, and C6 glioma cells, respectively, were similar to the EC50 values (323, 132, and 72 nM) observed for UDP-glucose.	Uridine Diphosphate Glucose	270-281	purinergic receptor P2Y14	Homo sapiens	137-151
19759354-6	2009	UDP and UDP-glucose also stimulated extracellular signal-regulated kinase (ERK) 1/2 phosphorylation in P2Y14 receptor-expressing HEK293 cells but not in wild-type HEK293 cells.	Uridine Diphosphate Glucose	8-19	mitogen-activated protein kinase 3	Homo sapiens	36-83
19759354-6	2009	UDP and UDP-glucose also stimulated extracellular signal-regulated kinase (ERK) 1/2 phosphorylation in P2Y14 receptor-expressing HEK293 cells but not in wild-type HEK293 cells.	Uridine Diphosphate Glucose	8-19	purinergic receptor P2Y14	Homo sapiens	103-117
19759354-4	2009	Not only was the human P2Y14 receptor activated by UDP-glucose, but it also was activated by UDP.	Uridine Diphosphate Glucose	51-62	purinergic receptor P2Y14	Homo sapiens	23-37
19759354-5	2009	The apparent efficacies of UDP and UDP-glucose were similar, and the EC50 values (74, 33, and 29 nM) for UDP-dependent activation of the P2Y14 receptor in HEK293, CHO, and C6 glioma cells, respectively, were similar to the EC50 values (323, 132, and 72 nM) observed for UDP-glucose.	Uridine Diphosphate Glucose	35-46	purinergic receptor P2Y14	Homo sapiens	137-151
19754426-5	2009	rPsUGE1 (recombinant P. sativum UGE1) expressed in Escherichia coli exhibited both UDP-Xyl 4-epimerase and UDP-Glc 4-epimerase activities with apparent Km values of 0.31, 0.29, 0.16 and 0.15 mM for UDP-Glc, UDP-Gal (UDP-galactose), UDP-Ara (UDP-L-arabinose) and UDP-Xyl respectively.	Uridine Diphosphate Glucose	107-114	UDP-D-glucose/UDP-D-galactose 4-epimerase 1	Arabidopsis thaliana	3-7
19648353-8	2009	GTA and GTB bind the donor analogs UDP-GlcNAc, UDP-Glc with affinities similar to those measured for UDP-Gal and UDP-GalNAc (GTB only), suggesting that the native donors and donor analogs bind to the GTA and GTB through similar interactions.	Uridine Diphosphate Glucose	35-42	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Homo sapiens	8-11
19528093-2	2009	Here we show that, in non-injured spinal cord parenchyma, GPR17, a P2Y-like receptor responding to both uracil nucleotides (e.g. UDP-glucose) and cysteinyl-leukotrienes (e.g. LTD4 and LTC4), is present on a subset of neurons and of oligodendrocytes at different stages of maturation, whereas it is not expressed by astrocytes.	Uridine Diphosphate Glucose	129-140	G protein-coupled receptor 17	Homo sapiens	58-63
19625605-6	2009	[35S]GTPgammaS binding in long-GPR17-expressing 1321N1 cells revealed concentration-dependent responses to uracil nucleotides (UDP-galactose = UDP > UDP-glucose) and cysteinyl leukotrienes (LTC4 > LTD4), which were counteracted by a purinergic (cangrelor) and a cysteinyl leukotriene antagonist (montelukast), respectively.	Uridine Diphosphate Glucose	152-163	G protein-coupled receptor 17	Homo sapiens	31-36
19528093-2	2009	Here we show that, in non-injured spinal cord parenchyma, GPR17, a P2Y-like receptor responding to both uracil nucleotides (e.g. UDP-glucose) and cysteinyl-leukotrienes (e.g. LTD4 and LTC4), is present on a subset of neurons and of oligodendrocytes at different stages of maturation, whereas it is not expressed by astrocytes.	Uridine Diphosphate Glucose	129-140	G protein-coupled receptor 17	Homo sapiens	67-84
19306919-1	2009	The aim of this review is to highlight the role of myo-inositol phosphate synthase (MIPS), which catalyses the first step in inositol biosynthesis and of sucrose synthase (Sus), an enzyme involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis.	Uridine Diphosphate Glucose	200-211	myo-inositol-3-phosphate synthase	Glycine max	51-82
19572637-1	2009	The P2Y(14) receptor is a G protein-coupled receptor activated by uridine-5"-diphosphoglucose and other nucleotide sugars that modulates immune function.	Uridine Diphosphate Glucose	66-93	purinergic receptor P2Y14	Homo sapiens	4-20
19502066-0	2009	Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5"-diphosphoglucose.	Uridine Diphosphate Glucose	108-135	purinergic receptor P2Y14	Homo sapiens	29-45
19502066-1	2009	The P2Y(14) receptor, a nucleotide signaling protein, is activated by uridine-5"-diphosphoglucose 1 and other uracil nucleotides.	Uridine Diphosphate Glucose	70-97	purinergic receptor P2Y14	Homo sapiens	4-20
19339661-8	2009	UDP-Glc promoted concentration-dependent and pertussis toxin-sensitive extracellular signal-regulated kinase (ERK) 1/2 phosphorylation in P2Y(14)-HEK293 cells.	Uridine Diphosphate Glucose	0-7	mitogen-activated protein kinase 3	Homo sapiens	71-118
19339661-10	2009	Consistent with this observation, no effect of UDP-Glc was observed in wild-type HL-60 cells, but UDP-Glc-promoted pertussis toxin-sensitive activation of ERK1/2 occurred after differentiation.	Uridine Diphosphate Glucose	98-105	mitogen-activated protein kinase 3	Homo sapiens	155-161
19306919-1	2009	The aim of this review is to highlight the role of myo-inositol phosphate synthase (MIPS), which catalyses the first step in inositol biosynthesis and of sucrose synthase (Sus), an enzyme involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis.	Uridine Diphosphate Glucose	200-211	myo-inositol-3-phosphate synthase	Glycine max	84-88
19306919-1	2009	The aim of this review is to highlight the role of myo-inositol phosphate synthase (MIPS), which catalyses the first step in inositol biosynthesis and of sucrose synthase (Sus), an enzyme involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis.	Uridine Diphosphate Glucose	200-211	sucrose synthase	Glycine max	154-170
19306919-1	2009	The aim of this review is to highlight the role of myo-inositol phosphate synthase (MIPS), which catalyses the first step in inositol biosynthesis and of sucrose synthase (Sus), an enzyme involved in UDP-glucose formation, the principal nucleoside diphosphate in the sucrose cleavage reaction and in trehalose biosynthesis.	Uridine Diphosphate Glucose	200-211	sucrose synthase	Glycine max	172-175
18573104-7	2008	LC/MS indicated that MdPGT1 could glycosylate phloretin in the presence of three sugar donors: UDP-glucose, UDP-xylose and UDP-galactose.	Uridine Diphosphate Glucose	95-106	phloretin 2'-O-glucosyltransferase	Malus domestica	21-27
19440050-7	2009	This partitioning of glucose in response to PAS kinase activation is due to phosphorylation of Ugp1, the enzyme primarily responsible for UDP-glucose production.	Uridine Diphosphate Glucose	138-149	PAS domain containing serine/threonine kinase	Mus musculus	44-54
19440050-7	2009	This partitioning of glucose in response to PAS kinase activation is due to phosphorylation of Ugp1, the enzyme primarily responsible for UDP-glucose production.	Uridine Diphosphate Glucose	138-149	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	95-99
19358821-1	2009	UDP-glucose dehydrogenase (UGDH) is an enzyme catalyzing the conversion of UDP-glucose to UDP-glucuronic acid.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
19454705-3	2009	We show in this report that P2RY14, a membrane receptor for UDP-glucose, is exclusively expressed in the epithelium, but not the stroma, of the FRT in humans and mice.	Uridine Diphosphate Glucose	60-71	purinergic receptor P2Y14	Homo sapiens	28-34
19454705-5	2009	UDP-glucose stimulated IL-8 production via P2RY14 in human endometrial epithelial cells but not stromal cells.	Uridine Diphosphate Glucose	0-11	C-X-C motif chemokine ligand 8	Homo sapiens	23-27
19454705-5	2009	UDP-glucose stimulated IL-8 production via P2RY14 in human endometrial epithelial cells but not stromal cells.	Uridine Diphosphate Glucose	0-11	purinergic receptor P2Y14	Homo sapiens	43-49
19454705-6	2009	Furthermore, UDP-glucose enhanced neutrophil chemotaxis in the presence of a human endometrial epithelial cell line in an IL-8-dependent manner.	Uridine Diphosphate Glucose	13-24	C-X-C motif chemokine ligand 8	Homo sapiens	122-126
19454705-7	2009	Administration of UDP-glucose into the mouse uterus induced expression of macrophage inflammatory protein-2 and keratinocyte-derived cytokine, two murine chemokines that are functional homologues of IL-8, and augmented endometrial neutrophil recruitment.	Uridine Diphosphate Glucose	18-29	chemokine (C-X-C motif) ligand 2	Mus musculus	74-107
19454705-7	2009	Administration of UDP-glucose into the mouse uterus induced expression of macrophage inflammatory protein-2 and keratinocyte-derived cytokine, two murine chemokines that are functional homologues of IL-8, and augmented endometrial neutrophil recruitment.	Uridine Diphosphate Glucose	18-29	chemokine (C-X-C motif) ligand 15	Mus musculus	199-203
19454705-8	2009	Reduced expression of P2RY14 by small interfering RNA gene silencing attenuated LPS- or UDP-glucose-induced leukocytosis in the mouse uterus.	Uridine Diphosphate Glucose	88-99	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	22-28
19454705-9	2009	These results suggest that UDP-glucose and its receptor P2RY14 are key front line players able to trigger innate mucosal immune responses in the FRT bypassing the recognition of pathogen-associated molecular patterns.	Uridine Diphosphate Glucose	27-38	purinergic receptor P2Y14	Homo sapiens	56-62
19366709-1	2009	UDP-glucose pyrophosphorylase (UGPase) produces UDP-glucose which is essential for sucrose and polysaccharide synthesis.	Uridine Diphosphate Glucose	0-11	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	31-37
19164486-0	2009	UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms.	Uridine Diphosphate Glucose	0-11	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	47-52
19244115-1	2009	UDP-glucose dehydrogenase (UGDH) oxidizes UDP-glucose to UDP-glucuronate, an essential precursor for production of hyaluronan (HA), proteoglycans, and xenobiotic glucuronides.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
19004876-5	2009	The cDNA encoding TPS, which converts uridine-5"-diphosphoglucose and glucose-6-phosphate to trehalose-6-phosphate, was cloned from the fat body of H. armigera using rapid amplification of cDNA ends (RACE).	Uridine Diphosphate Glucose	38-65	Trehalose-6-phosphate synthase 1	Drosophila melanogaster	18-21
22303248-3	2009	Firstly, trehalose-6-phosphate synthase (TPS) converts UDP-glucose and glucose-6-phosphate to trehalose-6-phosphate (T6P); secondly, T6P-phosphatase (TPP) converts T6P into trehalose and Pi.	Uridine Diphosphate Glucose	55-66	trehalose-6-phosphate synthase	Arabidopsis thaliana	9-39
22303248-3	2009	Firstly, trehalose-6-phosphate synthase (TPS) converts UDP-glucose and glucose-6-phosphate to trehalose-6-phosphate (T6P); secondly, T6P-phosphatase (TPP) converts T6P into trehalose and Pi.	Uridine Diphosphate Glucose	55-66	trehalose-6-phosphate synthase	Arabidopsis thaliana	41-44
22303248-3	2009	Firstly, trehalose-6-phosphate synthase (TPS) converts UDP-glucose and glucose-6-phosphate to trehalose-6-phosphate (T6P); secondly, T6P-phosphatase (TPP) converts T6P into trehalose and Pi.	Uridine Diphosphate Glucose	55-66	thylakoid processing peptide	Arabidopsis thaliana	133-148
22303248-3	2009	Firstly, trehalose-6-phosphate synthase (TPS) converts UDP-glucose and glucose-6-phosphate to trehalose-6-phosphate (T6P); secondly, T6P-phosphatase (TPP) converts T6P into trehalose and Pi.	Uridine Diphosphate Glucose	55-66	thylakoid processing peptide	Arabidopsis thaliana	150-153
19904445-1	2008	Galactosemia is an inborn error of galactose metabolism, caused by an abnormality in the conversion of galactose and uridine diphosphoglucose to glucose-1-phosphate and uridine diphosphogalactose through the action of 3 sequential enzymes: galactokinase (GALK), galactose- 1-phosphate uridyltransferase (GALT), and uridine phosphogalactose 4-epimerase (GALE).	Uridine Diphosphate Glucose	117-141	galactokinase 1	Homo sapiens	240-253
19904445-1	2008	Galactosemia is an inborn error of galactose metabolism, caused by an abnormality in the conversion of galactose and uridine diphosphoglucose to glucose-1-phosphate and uridine diphosphogalactose through the action of 3 sequential enzymes: galactokinase (GALK), galactose- 1-phosphate uridyltransferase (GALT), and uridine phosphogalactose 4-epimerase (GALE).	Uridine Diphosphate Glucose	117-141	galactokinase 1	Homo sapiens	255-259
19904445-1	2008	Galactosemia is an inborn error of galactose metabolism, caused by an abnormality in the conversion of galactose and uridine diphosphoglucose to glucose-1-phosphate and uridine diphosphogalactose through the action of 3 sequential enzymes: galactokinase (GALK), galactose- 1-phosphate uridyltransferase (GALT), and uridine phosphogalactose 4-epimerase (GALE).	Uridine Diphosphate Glucose	117-141	galactose-1-phosphate uridylyltransferase	Homo sapiens	262-302
19904445-1	2008	Galactosemia is an inborn error of galactose metabolism, caused by an abnormality in the conversion of galactose and uridine diphosphoglucose to glucose-1-phosphate and uridine diphosphogalactose through the action of 3 sequential enzymes: galactokinase (GALK), galactose- 1-phosphate uridyltransferase (GALT), and uridine phosphogalactose 4-epimerase (GALE).	Uridine Diphosphate Glucose	117-141	galactose-1-phosphate uridylyltransferase	Homo sapiens	304-308
18693752-7	2008	The genetic basis of UDP-glucose release was explored through analysis of deletion mutants, aided by development of a novel bioassay for UDP-glucose based on signaling through heterologously expressed human P2Y 14 receptors.	Uridine Diphosphate Glucose	21-32	purinergic receptor P2Y14	Homo sapiens	207-213
18693752-7	2008	The genetic basis of UDP-glucose release was explored through analysis of deletion mutants, aided by development of a novel bioassay for UDP-glucose based on signaling through heterologously expressed human P2Y 14 receptors.	Uridine Diphosphate Glucose	137-148	purinergic receptor P2Y14	Homo sapiens	207-213
18693752-8	2008	Using this assay, an elevated rate of UDP-glucose release was demonstrated in mutants lacking the putative Golgi nucleotide sugar transporter YMD8.	Uridine Diphosphate Glucose	38-49	Ymd8p	Saccharomyces cerevisiae S288C	142-146
18693752-9	2008	An increased rate of UDP-glucose release in ymd8Delta was reduced by deletion of the YEA4 UDP- N-acetylglucosamine or the HUT1 UDP-galactose transporters, and overexpression of YEA4 or HUT1 increased the rate of UDP-glucose release.	Uridine Diphosphate Glucose	21-32	Yea4p	Saccharomyces cerevisiae S288C	85-89
18693752-9	2008	An increased rate of UDP-glucose release in ymd8Delta was reduced by deletion of the YEA4 UDP- N-acetylglucosamine or the HUT1 UDP-galactose transporters, and overexpression of YEA4 or HUT1 increased the rate of UDP-glucose release.	Uridine Diphosphate Glucose	21-32	UDP-galactose transporter HUT1	Saccharomyces cerevisiae S288C	122-126
18693752-9	2008	An increased rate of UDP-glucose release in ymd8Delta was reduced by deletion of the YEA4 UDP- N-acetylglucosamine or the HUT1 UDP-galactose transporters, and overexpression of YEA4 or HUT1 increased the rate of UDP-glucose release.	Uridine Diphosphate Glucose	21-32	Yea4p	Saccharomyces cerevisiae S288C	177-181
18693752-9	2008	An increased rate of UDP-glucose release in ymd8Delta was reduced by deletion of the YEA4 UDP- N-acetylglucosamine or the HUT1 UDP-galactose transporters, and overexpression of YEA4 or HUT1 increased the rate of UDP-glucose release.	Uridine Diphosphate Glucose	21-32	UDP-galactose transporter HUT1	Saccharomyces cerevisiae S288C	185-189
19904445-1	2008	Galactosemia is an inborn error of galactose metabolism, caused by an abnormality in the conversion of galactose and uridine diphosphoglucose to glucose-1-phosphate and uridine diphosphogalactose through the action of 3 sequential enzymes: galactokinase (GALK), galactose- 1-phosphate uridyltransferase (GALT), and uridine phosphogalactose 4-epimerase (GALE).	Uridine Diphosphate Glucose	117-141	UDP-galactose-4-epimerase	Homo sapiens	353-357
18344420-5	2008	The outer cell wall layer of pollen tubes consists of pectins, but the inner layer is composed of cellulose and callose; both polymers require metabolic precursors in the form of UDP-glucose, which is synthesized by Sus.	Uridine Diphosphate Glucose	179-190	sucrose synthase	Nicotiana tabacum	216-219
18690346-9	2008	Despite this, UDP-glucose (up to 100 muM) did not induce platelet aggregation in either PRP or whole blood, and did not potentiate aggregation induced by other agonists.	Uridine Diphosphate Glucose	14-25	latexin	Homo sapiens	37-40
18403407-3	2008	In a screen for maternal factors involved in embryo patterning, we isolated mutations in Drosophila ALG5, a UDP-glucose:dolichyl-phosphate glucosyltransferase.	Uridine Diphosphate Glucose	108-119	wollknaeuel	Drosophila melanogaster	100-104
18496872-7	2008	Those results all together indicate that UTP and UDP-Glc syntheses in CHO cells cultivated in SF-RPMI medium in batch process, could be limiting during the glycosylation processes of the recombinant IFN-gamma.	Uridine Diphosphate Glucose	49-56	interferon gamma	Homo sapiens	199-208
18395530-1	2008	UDP-glucose pyrophosphorylase (UGPase) is an important enzyme in the production (and conversions) of UDP-glucose, a key precursor for carbohydrate biosynthesis.	Uridine Diphosphate Glucose	0-11	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	31-37
17433749-1	2007	Mice with deletion of the galactose-1-phosphate uridyltransferase (GALT) gene were examined for their ability to form (13)C labeled hepatic UDP glucose from administered 1-(13)C galactose.	Uridine Diphosphate Glucose	140-151	galactose-1-phosphate uridyl transferase	Mus musculus	26-65
18252808-2	2008	The P2Y(14) receptor (P2Y(14)-R) is activated by at least four naturally occurring UDP sugars, with UDP-glucose (UDP-Glc) being the most potent agonist.	Uridine Diphosphate Glucose	100-111	purinergic receptor P2Y14	Homo sapiens	4-20
18252808-2	2008	The P2Y(14) receptor (P2Y(14)-R) is activated by at least four naturally occurring UDP sugars, with UDP-glucose (UDP-Glc) being the most potent agonist.	Uridine Diphosphate Glucose	100-111	purinergic receptor P2Y14	Homo sapiens	22-31
18252808-2	2008	The P2Y(14) receptor (P2Y(14)-R) is activated by at least four naturally occurring UDP sugars, with UDP-glucose (UDP-Glc) being the most potent agonist.	Uridine Diphosphate Glucose	113-120	purinergic receptor P2Y14	Homo sapiens	4-20
18252808-2	2008	The P2Y(14) receptor (P2Y(14)-R) is activated by at least four naturally occurring UDP sugars, with UDP-glucose (UDP-Glc) being the most potent agonist.	Uridine Diphosphate Glucose	113-120	purinergic receptor P2Y14	Homo sapiens	22-31
18204471-0	2008	Thrombin-promoted release of UDP-glucose from human astrocytoma cells.	Uridine Diphosphate Glucose	29-40	coagulation factor II, thrombin	Homo sapiens	0-8
18204471-1	2008	BACKGROUND AND PURPOSE: The P2Y14 receptor is activated by UDP-sugars, most potently by UDP-glucose, but not by free nucleotides, suggesting that UDP-glucose is the cognate agonist for this receptor.	Uridine Diphosphate Glucose	88-99	purinergic receptor P2Y14	Homo sapiens	28-42
18204471-1	2008	BACKGROUND AND PURPOSE: The P2Y14 receptor is activated by UDP-sugars, most potently by UDP-glucose, but not by free nucleotides, suggesting that UDP-glucose is the cognate agonist for this receptor.	Uridine Diphosphate Glucose	146-157	purinergic receptor P2Y14	Homo sapiens	28-42
18204471-6	2008	KEY RESULTS: Thrombin and the protease-activating receptor-1 (PAR1) peptide TFLLRNPNDK (PAR1-AP) evoked the release of UDP-glucose and ATP, which was accompanied by enhanced inositol phosphate formation.	Uridine Diphosphate Glucose	119-130	coagulation factor II, thrombin	Homo sapiens	13-21
18204471-6	2008	KEY RESULTS: Thrombin and the protease-activating receptor-1 (PAR1) peptide TFLLRNPNDK (PAR1-AP) evoked the release of UDP-glucose and ATP, which was accompanied by enhanced inositol phosphate formation.	Uridine Diphosphate Glucose	119-130	coagulation factor II thrombin receptor	Homo sapiens	30-60
18204471-6	2008	KEY RESULTS: Thrombin and the protease-activating receptor-1 (PAR1) peptide TFLLRNPNDK (PAR1-AP) evoked the release of UDP-glucose and ATP, which was accompanied by enhanced inositol phosphate formation.	Uridine Diphosphate Glucose	119-130	coagulation factor II thrombin receptor	Homo sapiens	62-66
18204471-6	2008	KEY RESULTS: Thrombin and the protease-activating receptor-1 (PAR1) peptide TFLLRNPNDK (PAR1-AP) evoked the release of UDP-glucose and ATP, which was accompanied by enhanced inositol phosphate formation.	Uridine Diphosphate Glucose	119-130	coagulation factor II thrombin receptor	Homo sapiens	88-92
18204471-11	2008	CONCLUSIONS AND IMPLICATIONS: PAR1-evoked UDP-glucose release reflected a Ca2+-dependent mechanism, engaging additional signalling independently of G(i) and Rho kinase activation and requiring a functional actin cytoskeleton and Golgi structures.	Uridine Diphosphate Glucose	42-53	coagulation factor II thrombin receptor	Homo sapiens	30-34
18204471-13	2008	Given the presence of P2Y14 receptors in astrocytes, UDP-glucose may have important autocrine/paracrine functions in the brain.	Uridine Diphosphate Glucose	53-64	purinergic receptor P2Y14	Homo sapiens	22-27
18419595-7	2008	Conversely, uracil nucleotides (UTP, UDP and UDPglucose) had no effect "per se", but fully counteracted the deleterious effects induced by adenine nucleotides and TNF-alpha, even if added to cardiomyocytes after beginning exposure to these cell death-inducing agents.	Uridine Diphosphate Glucose	45-55	tumor necrosis factor	Mus musculus	163-172
18424616-1	2008	Sucrose phosphate synthase (SPS) catalyzes the transfer of a glycosyl group from an activated donor sugar, such as uridine diphosphate glucose (UDP-Glc), to a saccharide acceptor D-fructose 6-phosphate (F6P), resulting in the formation of UDP and D-sucrose-6"-phosphate (S6P).	Uridine Diphosphate Glucose	115-142	decaprenyl diphosphate synthase subunit 1	Homo sapiens	0-26
18424616-1	2008	Sucrose phosphate synthase (SPS) catalyzes the transfer of a glycosyl group from an activated donor sugar, such as uridine diphosphate glucose (UDP-Glc), to a saccharide acceptor D-fructose 6-phosphate (F6P), resulting in the formation of UDP and D-sucrose-6"-phosphate (S6P).	Uridine Diphosphate Glucose	115-142	decaprenyl diphosphate synthase subunit 1	Homo sapiens	28-31
18424616-1	2008	Sucrose phosphate synthase (SPS) catalyzes the transfer of a glycosyl group from an activated donor sugar, such as uridine diphosphate glucose (UDP-Glc), to a saccharide acceptor D-fructose 6-phosphate (F6P), resulting in the formation of UDP and D-sucrose-6"-phosphate (S6P).	Uridine Diphosphate Glucose	144-151	decaprenyl diphosphate synthase subunit 1	Homo sapiens	0-26
18424616-1	2008	Sucrose phosphate synthase (SPS) catalyzes the transfer of a glycosyl group from an activated donor sugar, such as uridine diphosphate glucose (UDP-Glc), to a saccharide acceptor D-fructose 6-phosphate (F6P), resulting in the formation of UDP and D-sucrose-6"-phosphate (S6P).	Uridine Diphosphate Glucose	144-151	decaprenyl diphosphate synthase subunit 1	Homo sapiens	28-31
17993619-7	2008	This effect is most pronounced for the uridine nucleotides UDP and UTP and the sugar nucleotide UDP-glucose, ligands of P2Y(6), P2Y(4), and P2Y(14), respectively.	Uridine Diphosphate Glucose	96-107	pyrimidinergic receptor P2Y6	Homo sapiens	120-126
17993619-7	2008	This effect is most pronounced for the uridine nucleotides UDP and UTP and the sugar nucleotide UDP-glucose, ligands of P2Y(6), P2Y(4), and P2Y(14), respectively.	Uridine Diphosphate Glucose	96-107	pyrimidinergic receptor P2Y4	Homo sapiens	128-134
17993619-7	2008	This effect is most pronounced for the uridine nucleotides UDP and UTP and the sugar nucleotide UDP-glucose, ligands of P2Y(6), P2Y(4), and P2Y(14), respectively.	Uridine Diphosphate Glucose	96-107	purinergic receptor P2Y14	Homo sapiens	140-147
17442666-5	2007	The K(m) values of PA2022 and PA3559 for UDP-glucose are approximately 0.1 and 0.4 mM, whereas the K(m) values for NAD(+) are 0.5 and 2.0 mM, respectively.	Uridine Diphosphate Glucose	41-52	UDP-glucose 6-dehydrogenase	Pseudomonas aeruginosa PAO1	19-25
17442666-5	2007	The K(m) values of PA2022 and PA3559 for UDP-glucose are approximately 0.1 and 0.4 mM, whereas the K(m) values for NAD(+) are 0.5 and 2.0 mM, respectively.	Uridine Diphosphate Glucose	41-52	nucleotide sugar dehydrogenase	Pseudomonas aeruginosa PAO1	30-36
17442666-6	2007	Compared with PA3559, PA2022 exhibits broader substrate specificity, utilizing TDP-glucose and UDP-N-acetylglucosamine with one-third the velocity of that with UDP-glucose.	Uridine Diphosphate Glucose	160-171	UDP-glucose 6-dehydrogenase	Pseudomonas aeruginosa PAO1	22-28
17178245-1	2007	The enzyme UDP-galactose-4-epimerase (GAL10) catalyzes a key step in galactose metabolism converting UDP-galactose to UDP-glucose which then can get metabolized through glycolysis and TCA cycle thus allowing the cell to use galactose as a carbon and energy source.	Uridine Diphosphate Glucose	118-129	bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase	Saccharomyces cerevisiae S288C	38-43
18164738-4	2008	UDP-glucosyltransferase (UGT) in the midgut could transfer glucose to each of the hydroxyl groups of quercetin, with a preference for formation of 5-O-glucoside, while quercetin 5,4"-di-O-glucoside was predominantly produced if the enzyme extracts of either the fat body or silk glands were incubated with quercetin 5-O-glucoside and UDP-glucose.	Uridine Diphosphate Glucose	334-345	UDP-glucosyltransferase	Bombyx mori	0-23
18164738-4	2008	UDP-glucosyltransferase (UGT) in the midgut could transfer glucose to each of the hydroxyl groups of quercetin, with a preference for formation of 5-O-glucoside, while quercetin 5,4"-di-O-glucoside was predominantly produced if the enzyme extracts of either the fat body or silk glands were incubated with quercetin 5-O-glucoside and UDP-glucose.	Uridine Diphosphate Glucose	334-345	UDP-glucosyltransferase	Bombyx mori	25-28
18368535-2	2008	The selective P2Y14 receptor agonist UDP-glucose (UDPG) derived from microbial sources dose dependently stimulated expression of cyclooxygenase-2 and inducible nitric oxide synthase, and potentiated the effects of bacterial lipopolysaccharide on nitric oxide production.	Uridine Diphosphate Glucose	37-48	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	14-19
18368535-2	2008	The selective P2Y14 receptor agonist UDP-glucose (UDPG) derived from microbial sources dose dependently stimulated expression of cyclooxygenase-2 and inducible nitric oxide synthase, and potentiated the effects of bacterial lipopolysaccharide on nitric oxide production.	Uridine Diphosphate Glucose	37-48	prostaglandin-endoperoxide synthase 2	Mus musculus	129-181
18974869-3	2008	Here we show that, in brain telencephalon, GPR17, a recently deorphanized receptor for both uracil nucleotides and cysLTs (e.g., UDP-glucose and LTD(4)), is normally present on neurons and on a subset of parenchymal quiescent oligodendrocyte precursor cells.	Uridine Diphosphate Glucose	129-140	G protein-coupled receptor 17	Homo sapiens	43-48
18974869-9	2008	To confirm a specific role for GPR17 in oligodendrocyte differentiation, the in vitro exposure of cortical pre-oligodendrocytes to the GPR17 endogenous ligands UDP-glucose and LTD(4) promoted the expression of myelin basic protein, confirming progression toward mature oligodendrocytes.	Uridine Diphosphate Glucose	160-171	G protein-coupled receptor 17	Homo sapiens	135-140
17433749-1	2007	Mice with deletion of the galactose-1-phosphate uridyltransferase (GALT) gene were examined for their ability to form (13)C labeled hepatic UDP glucose from administered 1-(13)C galactose.	Uridine Diphosphate Glucose	140-151	galactose-1-phosphate uridyl transferase	Mus musculus	67-71
17531808-3	2007	The paralogous yeast PAS kinases Psk1 and Psk2 phosphorylate UDP-glucose pyrophosphorylase (Ugp1), the primary producer of UDP-glucose, the glucose donor for glucan biosynthesis.	Uridine Diphosphate Glucose	61-72	serine/threonine protein kinase PSK1	Saccharomyces cerevisiae S288C	33-37
17499718-2	2007	The method couples the activities of two recombinant enzymes, UDP-glucose: curcumin glucosyltransferase from Catharanthus roseus (CaUGT2) and sucrose synthase from Arabidopsis thaliana (AtSUS1).	Uridine Diphosphate Glucose	62-73	sucrose synthase 1	Arabidopsis thaliana	186-192
17499718-3	2007	UDP, a product inhibitor of UDP-glucosyltransferase, was removed from the system and used for regeneration of UDP-glucose by the second enzyme, AtSUS1.	Uridine Diphosphate Glucose	110-121	sucrose synthase 1	Arabidopsis thaliana	144-150
17531808-3	2007	The paralogous yeast PAS kinases Psk1 and Psk2 phosphorylate UDP-glucose pyrophosphorylase (Ugp1), the primary producer of UDP-glucose, the glucose donor for glucan biosynthesis.	Uridine Diphosphate Glucose	61-72	serine/threonine protein kinase PSK2	Saccharomyces cerevisiae S288C	42-46
17531808-3	2007	The paralogous yeast PAS kinases Psk1 and Psk2 phosphorylate UDP-glucose pyrophosphorylase (Ugp1), the primary producer of UDP-glucose, the glucose donor for glucan biosynthesis.	Uridine Diphosphate Glucose	61-72	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	92-96
17531808-4	2007	Unexpectedly, phosphorylation of Ugp1 does not affect its catalytic activity but instead alters the terminal destination of the UDP-glucose it generates.	Uridine Diphosphate Glucose	128-139	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	33-37
17531808-6	2007	We provide data indicating that phosphorylation by Psk1 or Psk2 targets Ugp1 to the cell periphery, where the UDP-glucose it produces is in proximity to the site of glucan synthesis.	Uridine Diphosphate Glucose	110-121	serine/threonine protein kinase PSK1	Saccharomyces cerevisiae S288C	51-55
17531808-6	2007	We provide data indicating that phosphorylation by Psk1 or Psk2 targets Ugp1 to the cell periphery, where the UDP-glucose it produces is in proximity to the site of glucan synthesis.	Uridine Diphosphate Glucose	110-121	serine/threonine protein kinase PSK2	Saccharomyces cerevisiae S288C	59-63
17531808-6	2007	We provide data indicating that phosphorylation by Psk1 or Psk2 targets Ugp1 to the cell periphery, where the UDP-glucose it produces is in proximity to the site of glucan synthesis.	Uridine Diphosphate Glucose	110-121	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	72-76
17407275-0	2007	Structure-activity relationship of uridine 5"-diphosphoglucose analogues as agonists of the human P2Y14 receptor.	Uridine Diphosphate Glucose	35-62	purinergic receptor P2Y14	Homo sapiens	98-112
17407275-1	2007	UDP-glucose (UDPG) and derivatives are naturally occurring agonists of the Gi protein-coupled P2Y14 receptor, which occurs in the immune system.	Uridine Diphosphate Glucose	0-11	UDP-glucose pyrophosphorylase 2	Homo sapiens	13-17
17407275-1	2007	UDP-glucose (UDPG) and derivatives are naturally occurring agonists of the Gi protein-coupled P2Y14 receptor, which occurs in the immune system.	Uridine Diphosphate Glucose	0-11	purinergic receptor P2Y14	Homo sapiens	94-108
17303565-1	2007	Uridine diphosphate-glucose pyrophosphorylase (UGPase) represents a ubiquitous enzyme, which catalyzes the formation of UDP-glucose, a key metabolite of the carbohydrate pathways of all organisms.	Uridine Diphosphate Glucose	120-131	UDP-glucose pyrophosphorylase	Drosophila melanogaster	47-53
17303565-3	2007	Here we present the crystal structures of the L. major UGPase in its uncomplexed apo form (open conformation) and in complex with UDP-glucose (closed conformation).	Uridine Diphosphate Glucose	130-141	UDP-glucose pyrophosphorylase	Drosophila melanogaster	55-61
17341835-4	2007	Recombinant AtUSP expressed in Escherichia coli exhibited broad specificity toward monosaccharide 1-phosphates, resulting in the formation of various UDP-sugars such as UDP-glucose, -galactose, -glucuronic acid, -xylose and -L-arabinose.	Uridine Diphosphate Glucose	169-180	UDP-sugar pyrophosphorylase	Arabidopsis thaliana	12-17
17059404-3	2006	Although RPI is intimately involved with many biochemical pathways, media supplementation experiments suggest that the visible phenotype results from a defect in the production of pyrimidine-based sugar-nucleotide compounds, most likely uridine 5"-diphosphate-glucose, the presumed substrate of cellulose synthase.	Uridine Diphosphate Glucose	237-267	Ribose 5-phosphate isomerase, type A protein	Arabidopsis thaliana	9-12
17209547-1	2007	Human UDP-glucose dehydrogenase (UGDH) is a homohexameric enzyme that catalyzes two successive oxidations of UDP-glucose to yield UDP-glucuronic acid, an essential precursor for matrix polysaccharide and proteoglycan synthesis.	Uridine Diphosphate Glucose	6-17	UDP-glucose 6-dehydrogenase	Homo sapiens	33-37
17038119-7	2006	Our findings indicate alpha-(1,3)-glucan production requires the function of the AMY1 gene product, a novel protein with homology to the alpha-amylase family of glycosyl hydrolases, and UGP1, a UTP-glucose-1-phosphate uridylyltransferase which synthesizes UDP-glucose monomers.	Uridine Diphosphate Glucose	256-267	amylase 1, salivary	Mus musculus	81-85
17208963-6	2007	VvMYBPA1 did not activate the promoter of VvUFGT, which encodes the anthocyanin-specific enzyme UDP-glucose:flavonoid-3-O-glucosyltransferase, suggesting VvMYBPA1 is specific to regulation of PA biosynthesis in grapes.	Uridine Diphosphate Glucose	96-107	MYBPA1 protein	Vitis vinifera	0-8
17190829-0	2007	Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion.	Uridine Diphosphate Glucose	89-102	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	44-48
17190829-0	2007	Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion.	Uridine Diphosphate Glucose	89-102	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	49-53
17190829-2	2007	It has been suggested that the RHM2/MUM4 gene is involved in conversion of UDP-D-glucose to UDP-L-rhamnose on the basis of its effect on rhamnogalacturonan-I-directed development in Arabidopsis thaliana.	Uridine Diphosphate Glucose	75-88	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	31-35
17190829-2	2007	It has been suggested that the RHM2/MUM4 gene is involved in conversion of UDP-D-glucose to UDP-L-rhamnose on the basis of its effect on rhamnogalacturonan-I-directed development in Arabidopsis thaliana.	Uridine Diphosphate Glucose	75-88	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	36-40
17190829-6	2007	This suggests that RHM2 converts UDP-d-glucose to UDP-L-rhamnose via an UDP-4-keto-6-deoxy-D-glucose intermediate.	Uridine Diphosphate Glucose	33-46	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	19-23
17190829-8	2007	Moreover, a kinetic analysis of purified His(6)-tagged RHM2-N protein revealed 5.9-fold higher affinity of RHM2 for UDP-D-glucose than for dTDP-D-glucose, the preferred substrate for dTDP-D-glucose 4,6-dehydratase from bacteria.	Uridine Diphosphate Glucose	116-129	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	55-59
17190829-9	2007	RHM2-N activity is strongly inhibited by UDP-L-rhamnose, UDP-D-xylose, and UDP but not by other sugar nucleotides, suggesting that RHM2 maintains cytoplasmic levels of UDP-D-glucose and UDP-L-rhamnose via feedback inhibition by UDP-L-rhamnose and UDP-D-xylose.	Uridine Diphosphate Glucose	168-181	NAD-dependent epimerase/dehydratase family protein	Arabidopsis thaliana	0-4
16909288-1	2007	This study describes a systematic screen for secondary product UDP-glycosyltransferases (UGTs; EC 2.4.1) involved in seed development of oilseed rape (Brassica napus) and was aimed at identifying genes related to UGT84A9 encoding UDP-glucose:sinapate glucosyltransferase (EC 2.4.1.120), a proven target for molecular breeding approaches to reduce the content of anti-nutritive sinapate esters.	Uridine Diphosphate Glucose	230-241	UDP-glycosyltransferase 84A2-like	Brassica napus	213-220
17085977-2	2006	Here I report the isolation and characterization of an Arabidopsis thaliana UDP-glucose:SA glucosyltransferase1 (AtSGT1) gene using a tobacco SGT gene previously reported, whose product catalyzes the formation of both SAG and SGE.	Uridine Diphosphate Glucose	76-87	UDP-glucosyltransferase 74F2	Arabidopsis thaliana	113-119
16820147-8	2006	UDP-glucose (100 microM) also induced a modest increase in extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation, whereas the other sugar nucleotides had no effect on ERK1/2 activation.	Uridine Diphosphate Glucose	0-11	mitogen-activated protein kinase 1	Homo sapiens	59-100
16820147-8	2006	UDP-glucose (100 microM) also induced a modest increase in extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation, whereas the other sugar nucleotides had no effect on ERK1/2 activation.	Uridine Diphosphate Glucose	0-11	mitogen-activated protein kinase 3	Homo sapiens	102-108
17016747-7	2006	ADP in the P2Y(12) receptor was located deeper inside the receptor in comparison to other subtypes, and the uridine moiety of UDP-glucose in the P2Y(14) receptor was located even deeper and shifted toward TM7.	Uridine Diphosphate Glucose	126-137	purinergic receptor P2Y14	Homo sapiens	145-161
16298403-8	2006	Studies with recombinant SGT2 protein purified from yeast show that SGT2 glycosylation activity is highly specific for UDP-glucose as a sugar donor.	Uridine Diphosphate Glucose	119-130	Sgt2p	Saccharomyces cerevisiae S288C	25-29
16298403-8	2006	Studies with recombinant SGT2 protein purified from yeast show that SGT2 glycosylation activity is highly specific for UDP-glucose as a sugar donor.	Uridine Diphosphate Glucose	119-130	Sgt2p	Saccharomyces cerevisiae S288C	68-72
16298403-9	2006	This data establishes the function of the gene product (SGT2), as the primary UDP-glucose:solanidine glucosyltransferase in vivo.	Uridine Diphosphate Glucose	78-89	UDP-glucose flavonoid 3-O-glucosyltransferase 7-like	Solanum tuberosum	56-60
16805424-9	2006	These findings also suggest that slow hydrolysable UDP-glucose may accomplish long lasting signalling on P2Y14 receptors expressed in astrocytes.	Uridine Diphosphate Glucose	51-62	purinergic receptor P2Y14	Homo sapiens	105-110
16769084-2	2006	Reported here are the X-ray crystal structures of GnT I in complex with UDP-CH2-GlcNAc (a non-hydrolyzable C-glycosidic phosphonate), UDP-2-deoxy-2-fluoro-glucose, UDP-glucose and UDP.	Uridine Diphosphate Glucose	164-175	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	50-55
16475938-3	2006	P2Y2 and P2Y4 receptors are activated by UTP (the P2Y2, and the rat but not the human P2Y4 receptor are also activated by ATP), the P2Y6 receptor is activated by UDP, and the P2Y14 receptor by UDP-glucose.	Uridine Diphosphate Glucose	193-204	purinergic receptor P2Y2	Rattus norvegicus	0-4
16475938-3	2006	P2Y2 and P2Y4 receptors are activated by UTP (the P2Y2, and the rat but not the human P2Y4 receptor are also activated by ATP), the P2Y6 receptor is activated by UDP, and the P2Y14 receptor by UDP-glucose.	Uridine Diphosphate Glucose	193-204	pyrimidinergic receptor P2Y4	Homo sapiens	9-13
16475938-3	2006	P2Y2 and P2Y4 receptors are activated by UTP (the P2Y2, and the rat but not the human P2Y4 receptor are also activated by ATP), the P2Y6 receptor is activated by UDP, and the P2Y14 receptor by UDP-glucose.	Uridine Diphosphate Glucose	193-204	pyrimidinergic receptor P2Y6	Homo sapiens	132-145
16475938-3	2006	P2Y2 and P2Y4 receptors are activated by UTP (the P2Y2, and the rat but not the human P2Y4 receptor are also activated by ATP), the P2Y6 receptor is activated by UDP, and the P2Y14 receptor by UDP-glucose.	Uridine Diphosphate Glucose	193-204	purinergic receptor P2Y14	Homo sapiens	175-189
16644739-2	2006	Here we show that Arabidopsis thaliana has five genes encoding functional UDP-D-glucose/UDP-D-galactose 4-epimerase (named UGE1 to UGE5).	Uridine Diphosphate Glucose	74-87	UDP-D-glucose/UDP-D-galactose 4-epimerase 1	Arabidopsis thaliana	123-127
16644739-2	2006	Here we show that Arabidopsis thaliana has five genes encoding functional UDP-D-glucose/UDP-D-galactose 4-epimerase (named UGE1 to UGE5).	Uridine Diphosphate Glucose	74-87	UDP-D-glucose/UDP-D-galactose 4-epimerase 5	Arabidopsis thaliana	131-135
16817893-6	2006	Here we report a novel S. cerevisiae strain that coexpresses the Arabidopsis thaliana genes UGD1 and UXS3, which encode a UDP-glucose dehydrogenase (AtUGD1) and a UDP-glucuronic acid decarboxylase (AtUXS3), respectively, which are required for the conversion of UDP-D-glucose to UDP-D-xylose in plants.	Uridine Diphosphate Glucose	262-275	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	92-96
16817893-6	2006	Here we report a novel S. cerevisiae strain that coexpresses the Arabidopsis thaliana genes UGD1 and UXS3, which encode a UDP-glucose dehydrogenase (AtUGD1) and a UDP-glucuronic acid decarboxylase (AtUXS3), respectively, which are required for the conversion of UDP-D-glucose to UDP-D-xylose in plants.	Uridine Diphosphate Glucose	262-275	UDP-glucuronic acid decarboxylase 3	Arabidopsis thaliana	101-105
16817893-6	2006	Here we report a novel S. cerevisiae strain that coexpresses the Arabidopsis thaliana genes UGD1 and UXS3, which encode a UDP-glucose dehydrogenase (AtUGD1) and a UDP-glucuronic acid decarboxylase (AtUXS3), respectively, which are required for the conversion of UDP-D-glucose to UDP-D-xylose in plants.	Uridine Diphosphate Glucose	262-275	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	149-155
16817893-8	2006	Furthermore, we observed that overexpression of AtUGD1 caused a reduction in the UDP-D-glucose pool, whereas coexpression of AtUXS3 and AtUGD1 did not result in reduction of the UDP-D-glucose pool.	Uridine Diphosphate Glucose	81-94	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	48-54
16817893-9	2006	Enzymatic analysis of the purified hexamer His-AtUGD1 revealed that AtUGD1 activity is strongly inhibited by UDP-D-xylose, suggesting that AtUGD1 maintains intracellular levels of UDP-D-glucose in cooperation with AtUXS3 via the inhibition of AtUGD1 by UDP-D-xylose.	Uridine Diphosphate Glucose	180-193	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	47-53
16817893-9	2006	Enzymatic analysis of the purified hexamer His-AtUGD1 revealed that AtUGD1 activity is strongly inhibited by UDP-D-xylose, suggesting that AtUGD1 maintains intracellular levels of UDP-D-glucose in cooperation with AtUXS3 via the inhibition of AtUGD1 by UDP-D-xylose.	Uridine Diphosphate Glucose	180-193	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	68-74
16817893-9	2006	Enzymatic analysis of the purified hexamer His-AtUGD1 revealed that AtUGD1 activity is strongly inhibited by UDP-D-xylose, suggesting that AtUGD1 maintains intracellular levels of UDP-D-glucose in cooperation with AtUXS3 via the inhibition of AtUGD1 by UDP-D-xylose.	Uridine Diphosphate Glucose	180-193	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	68-74
16817893-9	2006	Enzymatic analysis of the purified hexamer His-AtUGD1 revealed that AtUGD1 activity is strongly inhibited by UDP-D-xylose, suggesting that AtUGD1 maintains intracellular levels of UDP-D-glucose in cooperation with AtUXS3 via the inhibition of AtUGD1 by UDP-D-xylose.	Uridine Diphosphate Glucose	180-193	UDP-glucuronic acid decarboxylase 3	Arabidopsis thaliana	214-220
16817893-9	2006	Enzymatic analysis of the purified hexamer His-AtUGD1 revealed that AtUGD1 activity is strongly inhibited by UDP-D-xylose, suggesting that AtUGD1 maintains intracellular levels of UDP-D-glucose in cooperation with AtUXS3 via the inhibition of AtUGD1 by UDP-D-xylose.	Uridine Diphosphate Glucose	180-193	UDP-glucose dehydrogenase 1	Arabidopsis thaliana	68-74
16495656-1	2006	The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis of complex carbohydrates such as hyaluronan in many cell types, and is required for detoxification of toxic compounds in the liver.	Uridine Diphosphate Glucose	11-22	UDP-glucose 6-dehydrogenase	Homo sapiens	38-42
16109883-2	2005	Recently, a UDP-glucose-specific G(i) protein-coupled P2Y receptor, namely P2Y(14), has been cloned.	Uridine Diphosphate Glucose	12-23	purinergic receptor P2Y14	Homo sapiens	75-82
17073734-1	2006	UDP-glucose dehydrogenase (UGDH) catalyzes the synthesis of UDP-glucuronic acid from UDP-glucose resulting in the formation of proteoglycans that are involved in promoting normal cellular growth and migration.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
16109883-4	2005	Evidence of functional expression of the P2Y(14) receptor in these cell lines was provided by calcium measurements after stimulation with uridine 5"-diphosphoglucose (UDP-glc).	Uridine Diphosphate Glucose	138-165	purinergic receptor P2Y14	Homo sapiens	41-57
16109883-4	2005	Evidence of functional expression of the P2Y(14) receptor in these cell lines was provided by calcium measurements after stimulation with uridine 5"-diphosphoglucose (UDP-glc).	Uridine Diphosphate Glucose	167-174	purinergic receptor P2Y14	Homo sapiens	41-57
16109883-6	2005	Moreover, UDP-glc increased secretion of the potent neutrophil chemoattractant CXCL8/IL-8 in A549 and BEAS-2B cells in a pertussis toxin-sensitive manner.	Uridine Diphosphate Glucose	10-17	C-X-C motif chemokine ligand 8	Homo sapiens	79-84
16109883-6	2005	Moreover, UDP-glc increased secretion of the potent neutrophil chemoattractant CXCL8/IL-8 in A549 and BEAS-2B cells in a pertussis toxin-sensitive manner.	Uridine Diphosphate Glucose	10-17	C-X-C motif chemokine ligand 8	Homo sapiens	85-89
16109883-7	2005	Moreover, reverse transcription and quantitative polymerase chain reaction revealed that UDP-glc modulated mRNA levels of IL-8/CXCL8.	Uridine Diphosphate Glucose	89-96	C-X-C motif chemokine ligand 8	Homo sapiens	122-126
16109883-7	2005	Moreover, reverse transcription and quantitative polymerase chain reaction revealed that UDP-glc modulated mRNA levels of IL-8/CXCL8.	Uridine Diphosphate Glucose	89-96	C-X-C motif chemokine ligand 8	Homo sapiens	127-132
15598734-7	2005	IroB transfers glucosyl groups from uridine-5"-diphosphoglucose to C5 of one, two, or three of the 2,3-dihydroxybenzoyl units of Ent to yield monoglucosyl-C-Ent (MGE), diglucosyl-C-Ent (DGE), and triglucosyl-C-Ent (TGE).	Uridine Diphosphate Glucose	36-63	Salmochelin siderophore glycosyltransferase IroB	Escherichia coli	0-4
16302980-1	2005	UDP-galactose 4-epimerase (GALE, EC 5.1.3.2) catalyses the interconversion of UDP-glucose and UDP-galactose.	Uridine Diphosphate Glucose	78-89	UDP-galactose-4-epimerase	Homo sapiens	0-25
16302980-1	2005	UDP-galactose 4-epimerase (GALE, EC 5.1.3.2) catalyses the interconversion of UDP-glucose and UDP-galactose.	Uridine Diphosphate Glucose	78-89	UDP-galactose-4-epimerase	Homo sapiens	27-31
16129668-0	2005	A novel cysteine-rich domain of Sep15 mediates the interaction with UDP-glucose:glycoprotein glucosyltransferase.	Uridine Diphosphate Glucose	68-79	selenoprotein F	Homo sapiens	32-37
16129668-3	2005	Although the precise function of Sep15 remains elusive, Sep15 co-purifies with UDP-glucose:glycoprotein glucosyltransferase (GT), an essential regulator of quality control mechanisms within the endoplasmic reticulum.	Uridine Diphosphate Glucose	79-90	selenoprotein F	Homo sapiens	56-61
16158268-1	2005	UDP-glucose dehydrogenase (UGDH) catalyzes two oxidations of UDP-glucose to yield UDP-glucuronic acid.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
15795221-4	2005	Here we report the three-dimensional structure of Gal10p in complex with NAD(+), UDP-glucose, and beta-D-galactose determined to 1.85-A resolution.	Uridine Diphosphate Glucose	81-92	bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase	Saccharomyces cerevisiae S288C	50-56
15907484-1	2005	This study describes the substrate recognition profile of UGT72E1, an UDP-glucose:glycosyltransferase of Arabidopsis thaliana that is the third member of a branch of glycosyltransferases, capable of conjugating lignin monomers and related metabolites.	Uridine Diphosphate Glucose	70-81	UDP-glucosyl transferase 72E1	Arabidopsis thaliana	58-65
15898741-4	2005	Amino acid sequencing and compositional analysis identified the UDP-glucose-binding site of hUGDH as the region containing the sequence, ASVGFGGSXFQK, corresponding to A268-K279 of the amino acid sequence of hUGDH.	Uridine Diphosphate Glucose	64-75	UDP-glucose 6-dehydrogenase	Homo sapiens	92-97
15898741-4	2005	Amino acid sequencing and compositional analysis identified the UDP-glucose-binding site of hUGDH as the region containing the sequence, ASVGFGGSXFQK, corresponding to A268-K279 of the amino acid sequence of hUGDH.	Uridine Diphosphate Glucose	64-75	UDP-glucose 6-dehydrogenase	Homo sapiens	208-213
15898741-10	2005	These results indicate that C276 plays an important role for efficient binding of UDP-glucose to hUGDH.	Uridine Diphosphate Glucose	82-93	UDP-glucose 6-dehydrogenase	Homo sapiens	97-102
15736931-0	2005	Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I. Beta-1,4-galactosyltransferase I (beta4Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in the presence of Mn(2+) ion (Gal-T activity) and also transfers Glc from UDP-Glc to GlcNAc (Glc-T activity), albeit at only 0.3% efficiency.	Uridine Diphosphate Glucose	289-296	beta-1,4-galactosyltransferase 1	Bos taurus	155-166
16081100-3	2005	Five structures of AGT have been determined: a binary complex with the UDP product and four ternary complexes with UDP or UDP-glucose and oligonucleotides containing an A:G, HMU:G (hydroxymethyl uracyl) or AP:G (apurinic/apyrimidinic) mismatch at the target base-pair.	Uridine Diphosphate Glucose	122-133	angiotensinogen	Homo sapiens	19-22
15843594-8	2005	In vitro enzyme assays showed that the glycosyltransferase from A. tumefaciens favours uridine diphosphogalactose (UDP-Gal) over UDP-Glc.	Uridine Diphosphate Glucose	129-136	glycosyl transferase family protein	Agrobacterium tumefaciens	39-58
16085831-3	2005	PslA shows strong similarities to UDP-glucose lipid carriers.	Uridine Diphosphate Glucose	34-45	biofilm formation protein PslA	Pseudomonas aeruginosa PAO1	0-4
15942662-5	2005	Furthermore, treatment with D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor which specifically reduces the activity of UDP-glucose:ceramide glucosyltransferase in combination with SM treatment, causes the viability of HBL-2 cells to be decreased more with neuraminidase pre-treatment than without it.	Uridine Diphosphate Glucose	142-153	neuraminidase 1	Homo sapiens	279-292
16002992-1	2005	UDP-glucose dehydrogenase (UGDH) catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is required in liver for the excretion of toxic compounds, and for the biosynthesis of complex carbohydrates, such as hyaluronan, in many cell types.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
15898741-0	2005	Identification of a UDP-glucose-binding site of human UDP-glucose dehydrogenase by photoaffinity labeling and cassette mutagenesis.	Uridine Diphosphate Glucose	20-31	UDP-glucose 6-dehydrogenase	Homo sapiens	54-79
15898741-1	2005	We have identified a UDP-glucose-binding site within human UDP-glucose dehydrogenase (hUGDH) by photoaffinity labeling with a specific probe, [(32)P]5N(3)UDP-glucose, and cassette mutagenesis using a synthetic hUGDH gene.	Uridine Diphosphate Glucose	21-32	UDP-glucose 6-dehydrogenase	Homo sapiens	59-84
15898741-1	2005	We have identified a UDP-glucose-binding site within human UDP-glucose dehydrogenase (hUGDH) by photoaffinity labeling with a specific probe, [(32)P]5N(3)UDP-glucose, and cassette mutagenesis using a synthetic hUGDH gene.	Uridine Diphosphate Glucose	21-32	UDP-glucose 6-dehydrogenase	Homo sapiens	86-91
15898741-1	2005	We have identified a UDP-glucose-binding site within human UDP-glucose dehydrogenase (hUGDH) by photoaffinity labeling with a specific probe, [(32)P]5N(3)UDP-glucose, and cassette mutagenesis using a synthetic hUGDH gene.	Uridine Diphosphate Glucose	21-32	UDP-glucose 6-dehydrogenase	Homo sapiens	210-215
15701638-1	2005	UDP-galactose 4"-epimerase (GALE) catalyzes the final step in the Leloir pathway of galactose metabolism, interconverting UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	140-151	UDP-galactose-4-epimerase	Homo sapiens	0-26
15701638-1	2005	UDP-galactose 4"-epimerase (GALE) catalyzes the final step in the Leloir pathway of galactose metabolism, interconverting UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	140-151	UDP-galactose-4-epimerase	Homo sapiens	28-32
15701638-7	2005	We found that GALE-null cells accumulated abnormally high levels of Gal-1-P and UDP-Gal and abnormally low levels of UDP-Glc and UDP-GlcNAc in the presence of galactose and that human GALE expression corrected each of these defects.	Uridine Diphosphate Glucose	117-124	UDP-galactose-4-epimerase	Homo sapiens	14-18
15381072-1	2004	The bacteriophage T4 alpha- and beta-glucosyltransferases (AGT and BGT) catalyse the transfer of glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine of T4 DNA in an alpha- and beta-conformation, respectively.	Uridine Diphosphate Glucose	110-134	a-gt alpha glucosyl transferase	Escherichia phage T4	59-62
15584955-4	2004	Low Km values for phenylacetothiohydroximic acid (approximately 6 microm) and UDP-glucose (approximately 50 microm) strongly suggest that thiohydroximates are in vivo substrates of UGT74B1.	Uridine Diphosphate Glucose	78-89	UDP-glucosyl transferase 74B1	Arabidopsis thaliana	181-188
15584955-2	2004	Here, we characterize a putative UDP-glucose:thiohydroximate S-glucosyltransferase, UGT74B1, to determine its role in the Arabidopsis glucosinolate pathway.	Uridine Diphosphate Glucose	33-44	UDP-glucosyl transferase 74B1	Arabidopsis thaliana	84-91
15175331-1	2004	UDP-galactose 4"-epimerase (GALE) interconverts UDP-galactose and UDP-glucose in the final step of the Leloir pathway.	Uridine Diphosphate Glucose	66-77	UDP-galactose-4-epimerase	Homo sapiens	0-26
15210713-1	2004	Glucosylceramide synthase (GlcT-1) catalyzes the formation of glucosylceramide (GlcCer), the core structure of major glycosphingolipids (GSLs), from ceramide and UDP-glucose.	Uridine Diphosphate Glucose	162-173	Glucosylceramide synthase	Drosophila melanogaster	0-25
15210713-1	2004	Glucosylceramide synthase (GlcT-1) catalyzes the formation of glucosylceramide (GlcCer), the core structure of major glycosphingolipids (GSLs), from ceramide and UDP-glucose.	Uridine Diphosphate Glucose	162-173	Glucosylceramide synthase	Drosophila melanogaster	27-33
15299033-2	2004	The best known and most widely distributed pathway of trehalose synthesis involves the transfer of glucose from UDP-glucose to glucose 6-phosphate to form trehalose-6-phosphate and UDP via the trehalose-6-phosphate synthase (TPS1).	Uridine Diphosphate Glucose	112-123	tryptase alpha/beta 1	Homo sapiens	225-229
15175331-1	2004	UDP-galactose 4"-epimerase (GALE) interconverts UDP-galactose and UDP-glucose in the final step of the Leloir pathway.	Uridine Diphosphate Glucose	66-77	UDP-galactose-4-epimerase	Homo sapiens	28-32
15102851-9	2004	We hypothesize that up-regulation of uda-1 favors hydrolysis of the glucosyltransferase inhibitory product UDP to UMP, and that the latter product then exits the lumen of the ER or pre-GA compartment in a coupled exchange with the entry of UDP-glucose, thereby further relieving ER stress by favoring protein re-glycosylation.	Uridine Diphosphate Glucose	240-251	Nucleoside-diphosphatase uda-1	Caenorhabditis elegans	37-42
15082721-5	2004	The heterologous expression of HFRC1 in the yeast revealed the multisubstrate specific transport activity of HFRC1 (for UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc), and GDP-mannose (GDP-Man), with apparent K(m) values of 8.0, 2.1, and 0.14 microm, respectively).	Uridine Diphosphate Glucose	158-169	solute carrier family 35 member D2	Homo sapiens	31-36
15082721-5	2004	The heterologous expression of HFRC1 in the yeast revealed the multisubstrate specific transport activity of HFRC1 (for UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc), and GDP-mannose (GDP-Man), with apparent K(m) values of 8.0, 2.1, and 0.14 microm, respectively).	Uridine Diphosphate Glucose	158-169	solute carrier family 35 member D2	Homo sapiens	109-114
15082721-5	2004	The heterologous expression of HFRC1 in the yeast revealed the multisubstrate specific transport activity of HFRC1 (for UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc), and GDP-mannose (GDP-Man), with apparent K(m) values of 8.0, 2.1, and 0.14 microm, respectively).	Uridine Diphosphate Glucose	145-152	solute carrier family 35 member D2	Homo sapiens	31-36
15082721-5	2004	The heterologous expression of HFRC1 in the yeast revealed the multisubstrate specific transport activity of HFRC1 (for UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc), and GDP-mannose (GDP-Man), with apparent K(m) values of 8.0, 2.1, and 0.14 microm, respectively).	Uridine Diphosphate Glucose	145-152	solute carrier family 35 member D2	Homo sapiens	109-114
15082721-6	2004	In the mammalian cells, HFRC1 transported UDP-GlcNAc and UDP-Glc, but not GDP-Man.	Uridine Diphosphate Glucose	42-49	solute carrier family 35 member D2	Homo sapiens	24-29
14764091-2	2004	UDPgalactose 4-epimerase (epimerase) catalyzes the reversible conversion between UDPgalactose and UDPglucose and is an important enzyme of the galactose metabolic pathway.	Uridine Diphosphate Glucose	98-108	UDP-galactose-4-epimerase	Homo sapiens	0-24
15044486-2	2004	UDP-glucose dehydrogenase (UGDH) catalyzes two oxidations of UDP-glucose to yield UDP-glucuronic acid.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
15044486-7	2004	We used crystal coordinates for Streptococcus pyogenes UGDH in complex with NAD+ cofactor and UDP-glucose substrate to generate a model of the enzyme active site.	Uridine Diphosphate Glucose	94-105	UDP-glucose 6-dehydrogenase	Homo sapiens	55-59
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	protein disulfide isomerase family A member 3	Homo sapiens	182-187
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	protein disulfide isomerase family A member 4	Homo sapiens	189-194
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	heat shock protein family A (Hsp70) member 5	Homo sapiens	196-201
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	heat shock protein 90 beta family member 1	Homo sapiens	203-208
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	hypoxia up-regulated 1	Homo sapiens	210-216
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	calreticulin	Homo sapiens	222-234
15020602-2	2004	This work reveals that a 65% reduction in the cellular UDP-Glc level causes up-regulation of the mitochondrial chaperone GRP75 and the endoplasmic reticulum (ER) resident chaperones GRP58, ERp72, GRP78, GRP94, GRP170, and calreticulin.	Uridine Diphosphate Glucose	55-62	heat shock protein family A (Hsp70) member 9	Homo sapiens	121-126
15053762-3	2004	The cloned cDNAs encoding the key enzymes of sinapine biosynthesis, UDP-glucose (UDP-Glc):B. napus sinapate glucosyltransferase (BnSGT1) and sinapoylglucose:B. napus choline sinapoyltransferase (BnSCT), were functionally expressed.	Uridine Diphosphate Glucose	68-79	UDP-glycosyltransferase 72B1-like	Brassica napus	108-127
15053762-3	2004	The cloned cDNAs encoding the key enzymes of sinapine biosynthesis, UDP-glucose (UDP-Glc):B. napus sinapate glucosyltransferase (BnSGT1) and sinapoylglucose:B. napus choline sinapoyltransferase (BnSCT), were functionally expressed.	Uridine Diphosphate Glucose	81-88	UDP-glycosyltransferase 72B1-like	Brassica napus	108-127
15120114-1	2004	The plant enzyme sucrose synthase (SuSy; EC 2.4.1.13) catalyzes the reversible conversion of sucrose and UDP into UDP-glucose (UDP-Glc) and fructose.	Uridine Diphosphate Glucose	114-125	sucrose synthase	Nicotiana tabacum	17-33
15120114-1	2004	The plant enzyme sucrose synthase (SuSy; EC 2.4.1.13) catalyzes the reversible conversion of sucrose and UDP into UDP-glucose (UDP-Glc) and fructose.	Uridine Diphosphate Glucose	127-134	sucrose synthase	Nicotiana tabacum	17-33
12709487-5	2003	UL-[(14)C]sucrose-loaded vesicles incubated with ATP and UDP produced [(14)C]UDP-Glc as determined by UDP-Glc dehydrogenase and by the ability of the product to bind to DEAE-cellulose and to co-migrate with authentic UDP-Glc on TLC.	Uridine Diphosphate Glucose	77-84	UDP-glucose 6-dehydrogenase	Homo sapiens	102-123
12970342-5	2003	The enzyme, previously assigned the identifier UGT73C5, catalyzes the transfer of glucose from UDP-glucose to the hydroxyl group at carbon 3 of deoxynivalenol.	Uridine Diphosphate Glucose	95-106	don-glucosyltransferase 1	Arabidopsis thaliana	47-54
12900416-6	2003	UGT78D1 catalyzed the transfer of rhamnose from UDP-rhamnose to the 3-OH position of quercetin and kaempferol, whereas UGT73C6 catalyzed the transfer of glucose from UDP-glucose to the 7-OH position of kaempferol-3-O-rhamnoside and quercetin-3-O-rhamnoside, respectively.	Uridine Diphosphate Glucose	166-177	UDP-glucosyl transferase 78D1	Arabidopsis thaliana	0-7
12900416-6	2003	UGT78D1 catalyzed the transfer of rhamnose from UDP-rhamnose to the 3-OH position of quercetin and kaempferol, whereas UGT73C6 catalyzed the transfer of glucose from UDP-glucose to the 7-OH position of kaempferol-3-O-rhamnoside and quercetin-3-O-rhamnoside, respectively.	Uridine Diphosphate Glucose	166-177	UDP-glucosyl transferase 73C6	Arabidopsis thaliana	119-126
12913004-10	2003	Whereas neither catalytic domain displayed detectable activity when expressed alone, co-expression of either catalytic domain with the noncatalytic amino-terminal portion of HUGT1 conferred UDP-Glc binding and transfer of glucose that was specific for unfolded glycoprotein substrates.	Uridine Diphosphate Glucose	190-197	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	174-179
14559350-1	2003	We have recently shown that UDP-glucose, and some related UDP-sugars, are potent agonists of the novel G protein-coupled receptor GPR105 (recently re-named P2Y(14)).	Uridine Diphosphate Glucose	28-39	purinergic receptor P2Y14	Homo sapiens	130-136
14559350-1	2003	We have recently shown that UDP-glucose, and some related UDP-sugars, are potent agonists of the novel G protein-coupled receptor GPR105 (recently re-named P2Y(14)).	Uridine Diphosphate Glucose	28-39	purinergic receptor P2Y14	Homo sapiens	156-163
12902497-0	2003	Human immature monocyte-derived dendritic cells express the G protein-coupled receptor GPR105 (KIAA0001, P2Y14) and increase intracellular calcium in response to its agonist, uridine diphosphoglucose.	Uridine Diphosphate Glucose	175-199	purinergic receptor P2Y14	Homo sapiens	87-93
12902497-0	2003	Human immature monocyte-derived dendritic cells express the G protein-coupled receptor GPR105 (KIAA0001, P2Y14) and increase intracellular calcium in response to its agonist, uridine diphosphoglucose.	Uridine Diphosphate Glucose	175-199	purinergic receptor P2Y14	Homo sapiens	95-103
12902497-0	2003	Human immature monocyte-derived dendritic cells express the G protein-coupled receptor GPR105 (KIAA0001, P2Y14) and increase intracellular calcium in response to its agonist, uridine diphosphoglucose.	Uridine Diphosphate Glucose	175-199	purinergic receptor P2Y14	Homo sapiens	105-110
12902497-6	2003	Putative functionality of the GPR105 receptor was demonstrated by an observed calcium flux in immature MDDC treated with the potent GPR105 agonist, uridine 5"-diphosphoglucose (UDP-glucose), while no response to the nucleotide sugar was seen in monocytes and mature MDDC.	Uridine Diphosphate Glucose	148-175	purinergic receptor P2Y14	Homo sapiens	30-36
12902497-6	2003	Putative functionality of the GPR105 receptor was demonstrated by an observed calcium flux in immature MDDC treated with the potent GPR105 agonist, uridine 5"-diphosphoglucose (UDP-glucose), while no response to the nucleotide sugar was seen in monocytes and mature MDDC.	Uridine Diphosphate Glucose	148-175	purinergic receptor P2Y14	Homo sapiens	132-138
12902497-6	2003	Putative functionality of the GPR105 receptor was demonstrated by an observed calcium flux in immature MDDC treated with the potent GPR105 agonist, uridine 5"-diphosphoglucose (UDP-glucose), while no response to the nucleotide sugar was seen in monocytes and mature MDDC.	Uridine Diphosphate Glucose	177-188	purinergic receptor P2Y14	Homo sapiens	30-36
12902497-6	2003	Putative functionality of the GPR105 receptor was demonstrated by an observed calcium flux in immature MDDC treated with the potent GPR105 agonist, uridine 5"-diphosphoglucose (UDP-glucose), while no response to the nucleotide sugar was seen in monocytes and mature MDDC.	Uridine Diphosphate Glucose	177-188	purinergic receptor P2Y14	Homo sapiens	132-138
12902497-8	2003	Moreover, immature MDDC from some donors treated with UDP-glucose exhibit an increase in expression of the costimulatory molecule CD86, which correlates with the intensity of the UDP-glucose-induced calcium flux.	Uridine Diphosphate Glucose	54-65	CD86 molecule	Homo sapiens	130-134
12902497-8	2003	Moreover, immature MDDC from some donors treated with UDP-glucose exhibit an increase in expression of the costimulatory molecule CD86, which correlates with the intensity of the UDP-glucose-induced calcium flux.	Uridine Diphosphate Glucose	179-190	CD86 molecule	Homo sapiens	130-134
14753129-2	2004	The GALT enzyme is responsible for the conversion of galactose-1-phosphate with UDP glucose to glucose-1-phosphate and UDP galactose.	Uridine Diphosphate Glucose	80-91	galactose-1-phosphate uridylyltransferase	Homo sapiens	4-8
14501191-5	2003	A transient expression assay showed that the product of this ORF was able to conjugate glucose from UDP-glucose with ecdysone confirming that the gene identified was indeed the SfMNPV egt gene.	Uridine Diphosphate Glucose	100-111	ecdysteroid UDP-glucosyltransferase	Spodoptera frugiperda multiple nucleopolyhedrovirus	184-187
12695547-7	2003	Consistent with the observation of significant extracellular UDP-glucose levels, expression of the UDP-glucose-activated P2Y(14) receptor in COS-7 cells resulted in G protein-promoted inositol phosphate accumulation that was partially reversed by enzymatic removal of UDP-glucose from the medium.	Uridine Diphosphate Glucose	61-72	purinergic receptor P2Y14	Homo sapiens	121-137
12695547-7	2003	Consistent with the observation of significant extracellular UDP-glucose levels, expression of the UDP-glucose-activated P2Y(14) receptor in COS-7 cells resulted in G protein-promoted inositol phosphate accumulation that was partially reversed by enzymatic removal of UDP-glucose from the medium.	Uridine Diphosphate Glucose	99-110	purinergic receptor P2Y14	Homo sapiens	121-137
12695547-8	2003	Taken together, these results indicate constitutive release of UDP-glucose from physiologically relevant tissues and suggest that UDP-glucose acts as an autocrine activator of the P2Y(14) receptor.	Uridine Diphosphate Glucose	63-74	purinergic receptor P2Y14	Homo sapiens	180-196
12695547-8	2003	Taken together, these results indicate constitutive release of UDP-glucose from physiologically relevant tissues and suggest that UDP-glucose acts as an autocrine activator of the P2Y(14) receptor.	Uridine Diphosphate Glucose	130-141	purinergic receptor P2Y14	Homo sapiens	180-196
12391315-3	2002	We found that sqv-4 encodes a protein similar to UDP-glucose dehydrogenases and showed that the SQV-4 protein specifically catalyzes the conversion of UDP-glucose to UDP-glucuronic acid, which is essential for the biosynthesis of chondroitin and heparan sulfate proteoglycans.	Uridine Diphosphate Glucose	49-60	UDP-glucose 6-dehydrogenase	Caenorhabditis elegans	14-19
12475971-5	2003	The bacterially expressed UGT74F2 enzyme catalyzed a conjugation reaction, with free anthranilate and UDP-glucose as substrates, that yielded the same fluorescent glucose ester compound as extracted from the trp1-100 mutant.	Uridine Diphosphate Glucose	102-113	UDP-glucosyltransferase 74F2	Arabidopsis thaliana	26-33
12671684-2	2003	UDP-glucose glycoprotein:glucosyltransferase (UGGT) is the sensor component of the calnexin cycle, which recognizes these glycoproteins when they are incompletely folded, and transfers a glucose residue from UDP-glucose to N-linked Man9-GlcNAc2 glycans.	Uridine Diphosphate Glucose	0-11	calnexin	Homo sapiens	83-91
12671684-2	2003	UDP-glucose glycoprotein:glucosyltransferase (UGGT) is the sensor component of the calnexin cycle, which recognizes these glycoproteins when they are incompletely folded, and transfers a glucose residue from UDP-glucose to N-linked Man9-GlcNAc2 glycans.	Uridine Diphosphate Glucose	0-11	mannosidase alpha class 1A member 1	Homo sapiens	232-236
12626383-5	2003	The GALT-deficient cells had 157+/-10 micromoles UDP-glucose/100 g protein and 25+/-5 micromoles UDP-galactose/100 g protein when grown in 0.1% glucose.	Uridine Diphosphate Glucose	49-60	galactose-1-phosphate uridylyltransferase	Homo sapiens	4-8
12626383-7	2003	When we transfected the GALT-deficient cells with either the hUGP2 or GALT gene, their UDP-glucose content increased to 305+/-28 micromoles/100 g protein (hUGP2-transfected) and 210+/-13 micromoles/100 g protein (GALT-transfected), respectively.	Uridine Diphosphate Glucose	87-98	galactose-1-phosphate uridylyltransferase	Homo sapiens	24-28
12626383-7	2003	When we transfected the GALT-deficient cells with either the hUGP2 or GALT gene, their UDP-glucose content increased to 305+/-28 micromoles/100 g protein (hUGP2-transfected) and 210+/-13 micromoles/100 g protein (GALT-transfected), respectively.	Uridine Diphosphate Glucose	87-98	UDP-glucose pyrophosphorylase 2	Homo sapiens	61-66
12626383-7	2003	When we transfected the GALT-deficient cells with either the hUGP2 or GALT gene, their UDP-glucose content increased to 305+/-28 micromoles/100 g protein (hUGP2-transfected) and 210+/-13 micromoles/100 g protein (GALT-transfected), respectively.	Uridine Diphosphate Glucose	87-98	galactose-1-phosphate uridylyltransferase	Homo sapiens	70-74
12626383-7	2003	When we transfected the GALT-deficient cells with either the hUGP2 or GALT gene, their UDP-glucose content increased to 305+/-28 micromoles/100 g protein (hUGP2-transfected) and 210+/-13 micromoles/100 g protein (GALT-transfected), respectively.	Uridine Diphosphate Glucose	87-98	galactose-1-phosphate uridylyltransferase	Homo sapiens	70-74
12429111-6	2002	DmUgt37a1 was expressed in lepidopteran insect cells and the ability of the enzyme to conjugate 38 potential substrates belonging to diverse chemical groups was assessed using UDP-glucose as sugar-donor.	Uridine Diphosphate Glucose	176-187	UDP-glycosyltransferase family 37 member A1	Drosophila melanogaster	0-9
12042319-8	2002	In vitro assays using a Golgi-enriched vesicle fraction obtained from Saccharomyces cerevisiae expressing AtUTr1-MycHis is able to transport UDP-galactose but also UDP-glucose.	Uridine Diphosphate Glucose	164-175	UDP-galactose transporter 1	Arabidopsis thaliana	106-112
12042319-10	2002	AtUTr1 is the first transporter described that is able to transport UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	86-97	UDP-galactose transporter 1	Arabidopsis thaliana	0-6
12011358-9	2002	Subsequent glucosylation assays revealed that in RGP1-containing tobacco extracts as well as in RGP2-containing tobacco extracts UDP-glucose is incorporated, indicating that an RGP2-containing complex is active.	Uridine Diphosphate Glucose	129-140	glycine-rich RNA-binding protein 4, mitochondrial-like	Nicotiana tabacum	96-100
12208133-1	2002	Human galactose-1-phosphate uridyltransferase (hGALT) is a central enzyme in the conserved pathway by which galactose is converted to energy, UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	160-171	galactose-1-phosphate uridylyltransferase	Homo sapiens	6-45
12208133-1	2002	Human galactose-1-phosphate uridyltransferase (hGALT) is a central enzyme in the conserved pathway by which galactose is converted to energy, UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	160-171	galactose-1-phosphate uridylyltransferase	Homo sapiens	47-52
12031484-9	2002	The data suggest that Ugdh is regulated via an osmoticum-dependent pathway, possibly related to the availability of osmotically active carbohydrate precursors to UDP-glucose, a substrate of UGDH.	Uridine Diphosphate Glucose	162-173	UDP-glucose 6-dehydrogenase	Bos taurus	22-26
12031484-9	2002	The data suggest that Ugdh is regulated via an osmoticum-dependent pathway, possibly related to the availability of osmotically active carbohydrate precursors to UDP-glucose, a substrate of UGDH.	Uridine Diphosphate Glucose	162-173	UDP-glucose 6-dehydrogenase	Bos taurus	190-194
12011358-9	2002	Subsequent glucosylation assays revealed that in RGP1-containing tobacco extracts as well as in RGP2-containing tobacco extracts UDP-glucose is incorporated, indicating that an RGP2-containing complex is active.	Uridine Diphosphate Glucose	129-140	glycine-rich RNA-binding protein 4, mitochondrial-like	Nicotiana tabacum	177-181
29712080-1	2001	Saturation transfer difference (STD) NMR experiments reveal the binding epitopes of UDP-Gal and UDP-Glc bound to the glycosyltransferase beta4Gal-T1.	Uridine Diphosphate Glucose	96-103	beta-1,4-galactosyltransferase 1	Homo sapiens	137-148
11735218-1	2001	It has recently been shown that UDP-glucose is a potent agonist of the orphan G-protein-coupled receptor (GPCR) KIAA0001.	Uridine Diphosphate Glucose	32-43	G protein-coupled receptor 34	Mus musculus	78-104
11735218-1	2001	It has recently been shown that UDP-glucose is a potent agonist of the orphan G-protein-coupled receptor (GPCR) KIAA0001.	Uridine Diphosphate Glucose	32-43	G protein-coupled receptor 34	Mus musculus	106-110
11735218-7	2001	Further analyses of the rat and mouse GPR105 proteins show that they are activated by the same agonists as the human receptor, responding to UDP-glucose and closely related molecules with similar affinities.	Uridine Diphosphate Glucose	141-152	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	38-44
12369950-4	2002	P2Y(2) and P2Y(4) receptors are activated by UTP (the P2Y(2) and the rat, but not the human P2Y(4) receptor are also activated by ATP), the P2Y(6) receptor is activated by UDP, and the P2Y(14) receptor by UDP-glucose.	Uridine Diphosphate Glucose	205-216	pyrimidinergic receptor P2Y6	Homo sapiens	140-155
12138245-0	2002	High-dose 5-Fluorouracil with uridine-diphosphoglucose rescue increases thymidylate synthase inhibition but not 5-Fluorouracil incorporation into RNA in murine tumors.	Uridine Diphosphate Glucose	30-54	thymidylate synthase	Mus musculus	72-92
29712080-3	2001	This observation explains why beta4Gal-T1 binds to UDP-Glc but is unable to transfer glucose to an acceptor substrate.	Uridine Diphosphate Glucose	51-58	beta-1,4-galactosyltransferase 1	Homo sapiens	30-41
11279032-2	2001	UDP-galactose 4-epimerase catalyzes the interconversion of UDP-galactose and UDP-glucose during normal galactose metabolism.	Uridine Diphosphate Glucose	77-88	UDP-galactose-4-epimerase	Homo sapiens	0-25
11485999-0	2001	alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine.	Uridine Diphosphate Glucose	112-123	lactalbumin alpha	Homo sapiens	0-17
11485999-0	2001	alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine.	Uridine Diphosphate Glucose	112-123	beta-1,4-galactosyltransferase 1	Homo sapiens	73-85
11485999-1	2001	Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.	Uridine Diphosphate Glucose	52-59	beta-1,4-galactosyltransferase 1	Homo sapiens	21-33
11485999-1	2001	Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.	Uridine Diphosphate Glucose	52-59	lactalbumin alpha	Homo sapiens	36-38
11485999-9	2001	In order to understand this property, we have determined the crystal structures of the Gal-T1.LA complex with UDP-Glc x Mn(2+) and with N-butanoyl-glucosamine (N-butanoyl-GlcN), a preferred sugar acceptor in the Glc-T activity.	Uridine Diphosphate Glucose	110-117	beta-1,4-galactosyltransferase 1	Homo sapiens	87-93
11574155-7	2001	Two other novel GPCR genes, GPR94 and GPR95, encoded a subfamily with the genes encoding the UDP-glucose and P2Y(12) receptors (sharing >50% identities in the TM regions).	Uridine Diphosphate Glucose	93-104	purinergic receptor P2Y13	Homo sapiens	28-33
11574155-7	2001	Two other novel GPCR genes, GPR94 and GPR95, encoded a subfamily with the genes encoding the UDP-glucose and P2Y(12) receptors (sharing >50% identities in the TM regions).	Uridine Diphosphate Glucose	93-104	G protein-coupled receptor 87	Homo sapiens	38-43
11592823-12	2001	We conclude that a hydroxyl group on amino acid 135 is required for the catalysis of uridyl transfer from UDP-glucose to UDP-galactose in the presence of galactose 1-phosphate, and plays a role in the bio-stability of hGALT.	Uridine Diphosphate Glucose	106-117	galactose-1-phosphate uridylyltransferase	Homo sapiens	218-223
11493010-1	2001	beta-Glucosyltransferase (BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA.	Uridine Diphosphate Glucose	113-137	b-gt beta glucosyl transferase	Escherichia phage T4	0-24
11493010-1	2001	beta-Glucosyltransferase (BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA.	Uridine Diphosphate Glucose	113-137	b-gt beta glucosyl transferase	Escherichia phage T4	26-29
11337504-2	2001	Glucosylceramide synthase (GCS) transfers glucose from UDP-Glc to ceramide, catalyzing the first glycosylation step in the formation of higher order glycosphingolipids.	Uridine Diphosphate Glucose	55-62	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	0-25
11337504-2	2001	Glucosylceramide synthase (GCS) transfers glucose from UDP-Glc to ceramide, catalyzing the first glycosylation step in the formation of higher order glycosphingolipids.	Uridine Diphosphate Glucose	55-62	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	27-30
11337504-4	2001	We previously identified His-193 of rat GCS as an important residue in UDP-Glc and GCS inhibitor binding; however, little else is known about the GCS active site.	Uridine Diphosphate Glucose	71-78	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	40-43
11459225-2	2001	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the initial step in GSL synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	152-163	UDP-glucose ceramide glucosyltransferase	Mus musculus	0-28
11459225-2	2001	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the initial step in GSL synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	152-163	UDP-glucose ceramide glucosyltransferase	Mus musculus	30-55
11459225-2	2001	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the initial step in GSL synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	152-163	UDP-glucose ceramide glucosyltransferase	Mus musculus	57-63
11283335-4	2001	These data suggest that UGT1 may act as a subunit of callose synthase that uses UDP-glucose to synthesize callose, a 1,3-beta-glucan.	Uridine Diphosphate Glucose	80-91	UDP-glucosyltransferase 75B1	Arabidopsis thaliana	24-28
11287126-6	2001	One is an ADP-sugar pyrophosphatase: it hydrolysed ADP-ribose, ADP-glucose and ADP-mannose, but not e.g. UDP-glucose, at similar rates.	Uridine Diphosphate Glucose	105-116	nudix hydrolase 5	Homo sapiens	10-35
11283335-4	2001	These data suggest that UGT1 may act as a subunit of callose synthase that uses UDP-glucose to synthesize callose, a 1,3-beta-glucan.	Uridine Diphosphate Glucose	80-91	callose synthase	Arabidopsis thaliana	53-69
11283335-7	2001	We propose that UGT1 may transfer UDP-glucose from sucrose synthase to the callose synthase and thus help form a substrate channel for the synthesis of callose at the forming cell plate.	Uridine Diphosphate Glucose	34-45	UDP-glucosyltransferase 75B1	Arabidopsis thaliana	16-20
11283335-7	2001	We propose that UGT1 may transfer UDP-glucose from sucrose synthase to the callose synthase and thus help form a substrate channel for the synthesis of callose at the forming cell plate.	Uridine Diphosphate Glucose	34-45	callose synthase	Arabidopsis thaliana	75-91
11429909-5	2001	GalT was also able to accept UDP-glucose as an activated sugar donor, giving rise to cellobiosyl derivatives of Rg1.	Uridine Diphosphate Glucose	29-40	protein phosphatase 1 regulatory subunit 3A	Homo sapiens	112-115
11171080-1	2001	UDP-glucose pyrophosphorylase (UGPase) is a key enzyme producing UDP-glucose, which is involved in an array of metabolic pathways concerned with, among other functions, the synthesis of sucrose and cellulose.	Uridine Diphosphate Glucose	0-11	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	31-37
10869565-0	2000	Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide.	Uridine Diphosphate Glucose	14-25	UDP-glucose ceramide glucosyltransferase	Homo sapiens	35-56
11800269-2	2001	Synthesis of the linear polymer is catalysed by UDP-glucose beta(1,3)-D-glucan beta(3)-D-glucosyltransferase.	Uridine Diphosphate Glucose	48-59	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	60-68
11098819-2	2000	Changes in the activity of UDP-Glucose:cyclic hydroxamic acid glucosyltransferase (EC 2.4.1.-) in wheat were investigated using the cyclic hydroxamic acids 2.4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) and its 7-methoxy derivative (DIMBOA) as sugar acceptors.	Uridine Diphosphate Glucose	27-38	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Triticum aestivum	62-81
11098819-5	2000	Two peaks in activity of UDP-Glucose:DIMBOA glucosyltransferase were detected using a Mono Q column, indicating the presence of at least two isozymes of this glucosyltransferase.	Uridine Diphosphate Glucose	25-36	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Triticum aestivum	44-63
11098819-5	2000	Two peaks in activity of UDP-Glucose:DIMBOA glucosyltransferase were detected using a Mono Q column, indicating the presence of at least two isozymes of this glucosyltransferase.	Uridine Diphosphate Glucose	25-36	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Triticum aestivum	158-177
11073956-0	2001	Recombinant Arabidopsis SQD1 converts udp-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose in vitro.	Uridine Diphosphate Glucose	38-49	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	24-28
11073956-3	2001	The formation of the sulfonic acid precursor, UDP-sulfoquinovose, from UDP-glucose and a sulfur donor is proposed to be catalyzed by the bacterial SQDB proteins or the orthologous plant SQD1 proteins.	Uridine Diphosphate Glucose	71-82	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	186-190
11073956-8	2001	Approximate K(m) values of 150 microm for UDP-glucose and 10 microm for sulfite were established for SQD1.	Uridine Diphosphate Glucose	42-53	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	101-105
11073956-9	2001	Based on our results, we propose that SQD1 catalyzes the formation of UDP-sulfoquinovose from UDP-glucose and sulfite, derived from the sulfate reduction pathway in the chloroplast.	Uridine Diphosphate Glucose	94-105	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	38-42
10913140-5	2000	Without altering the acceptor specificity of the transferase, the fusion with the epimerase changed the donor requirement of alpha1, 3-galactosyltransferase from UDP-galactose to UDP-glucose and decreased the cost for the synthesis of biomedically important Galalpha1,3Gal-terminated oligosaccharides by more than 40-fold.	Uridine Diphosphate Glucose	179-190	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Bos taurus	125-156
10801319-1	2000	UDP-galactose 4-epimerase catalyzes the interconversion of UDP-glucose and UDP-galactose during normal galactose metabolism.	Uridine Diphosphate Glucose	59-70	UDP-galactose-4-epimerase	Homo sapiens	0-25
10869565-1	2000	We report that the expression of mRNA and the activity of UDP-glucose:ceramide (Cer) glucosyltransferase-1 (GlcT-1) of human hepatoma Huh7 and mouse melanoma B16 cells increases after treatment with bacterial sphingomyelinase or upon addition of short-chain Cer.	Uridine Diphosphate Glucose	58-69	UDP-glucose ceramide glucosyltransferase	Homo sapiens	85-106
10869565-1	2000	We report that the expression of mRNA and the activity of UDP-glucose:ceramide (Cer) glucosyltransferase-1 (GlcT-1) of human hepatoma Huh7 and mouse melanoma B16 cells increases after treatment with bacterial sphingomyelinase or upon addition of short-chain Cer.	Uridine Diphosphate Glucose	58-69	UDP-glucose ceramide glucosyltransferase	Homo sapiens	108-114
10869565-1	2000	We report that the expression of mRNA and the activity of UDP-glucose:ceramide (Cer) glucosyltransferase-1 (GlcT-1) of human hepatoma Huh7 and mouse melanoma B16 cells increases after treatment with bacterial sphingomyelinase or upon addition of short-chain Cer.	Uridine Diphosphate Glucose	58-69	MIR7-3 host gene	Homo sapiens	134-138
10557279-1	1999	The SQD1 enzyme is believed to be involved in the biosynthesis of the sulfoquinovosyl headgroup of plant sulfolipids, catalyzing the transfer of SO(3)(-) to UDP-glucose.	Uridine Diphosphate Glucose	157-168	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	4-8
10764828-1	2000	The endoplasmic reticulum enzyme UDP-glucose glycoprotein:glucosyltransferase (UGGT) has the unique property of recognizing incompletely folded glycoproteins and, if they carry an N -linked Man(9)GlcNAc(2)oligosaccharide, of catalyzing the addition of a glucose residue from UDP-glucose.	Uridine Diphosphate Glucose	33-44	UDP-glucose glycoprotein glucosyltransferase 1	Rattus norvegicus	79-83
10764828-8	2000	Recombinant rat UGGT has a K (m) of 44 microM for UDP-glucose.	Uridine Diphosphate Glucose	50-61	UDP-glucose glycoprotein glucosyltransferase 1	Rattus norvegicus	16-20
10557279-2	1999	We have determined the structure of the complex of SQD1 from Arabidopsis thaliana with NAD(+) and the putative substrate UDP-glucose at 1.6-A resolution.	Uridine Diphosphate Glucose	121-132	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	51-55
9918791-1	1998	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the first step in glycosphingolipid synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	164-175	UDP-glucose ceramide glucosyltransferase	Mus musculus	0-28
10393098-0	1999	Histidine-193 of rat glucosylceramide synthase resides in a UDP-glucose- and inhibitor (D-threo-1-phenyl-2-decanoylamino-3-morpholinopropan-1-ol)-binding region: a biochemical and mutational study.	Uridine Diphosphate Glucose	60-71	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	21-46
10393098-1	1999	Glucosylceramide synthase (GCS) catalyses the transfer of glucose from UDP-glucose (UDP-Glc) to ceramide to form glucosylceramide, the common precursor of most higher-order glycosphingolipids.	Uridine Diphosphate Glucose	71-82	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	0-25
10393098-1	1999	Glucosylceramide synthase (GCS) catalyses the transfer of glucose from UDP-glucose (UDP-Glc) to ceramide to form glucosylceramide, the common precursor of most higher-order glycosphingolipids.	Uridine Diphosphate Glucose	71-82	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	27-30
10393098-1	1999	Glucosylceramide synthase (GCS) catalyses the transfer of glucose from UDP-glucose (UDP-Glc) to ceramide to form glucosylceramide, the common precursor of most higher-order glycosphingolipids.	Uridine Diphosphate Glucose	84-91	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	0-25
10393098-1	1999	Glucosylceramide synthase (GCS) catalyses the transfer of glucose from UDP-glucose (UDP-Glc) to ceramide to form glucosylceramide, the common precursor of most higher-order glycosphingolipids.	Uridine Diphosphate Glucose	84-91	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	27-30
10393098-5	1999	The histidine-modifying agent diethyl pyrocarbonate (DEPC) inhibited recombinant rat GCS expressed in bacteria; this inhibition was rapidly reversible by hydroxylamine and could be diminished by preincubation of GCS with UDP-Glc.	Uridine Diphosphate Glucose	221-228	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	212-215
10393098-6	1999	These data suggest that DEPC acts on histidine residues within or near the UDP-Glc-binding site of GCS.	Uridine Diphosphate Glucose	75-82	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	99-102
10393098-9	1999	These results indicate that His193 is the primary target of DEPC and is at, or near, the UDP-Glc-binding site of GCS.	Uridine Diphosphate Glucose	89-96	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	113-116
10318825-0	1999	Modification of the T cell antigen receptor (TCR) complex by UDP-glucose:glycoprotein glucosyltransferase.	Uridine Diphosphate Glucose	61-72	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	20-43
10318825-0	1999	Modification of the T cell antigen receptor (TCR) complex by UDP-glucose:glycoprotein glucosyltransferase.	Uridine Diphosphate Glucose	61-72	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	45-48
10318825-4	1999	Here we evaluated the modification of TCR glycoproteins by the endoplasmic reticulum folding sensor enzyme UDP-glucose:glycoprotein glucosyltransferase (GT) as a unique and sensitive indicator of how TCR subunits assembled into multisubunit complexes are perceived by the endoplasmic reticulum quality control system.	Uridine Diphosphate Glucose	107-118	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	38-41
10318825-4	1999	Here we evaluated the modification of TCR glycoproteins by the endoplasmic reticulum folding sensor enzyme UDP-glucose:glycoprotein glucosyltransferase (GT) as a unique and sensitive indicator of how TCR subunits assembled into multisubunit complexes are perceived by the endoplasmic reticulum quality control system.	Uridine Diphosphate Glucose	107-118	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	200-203
9867864-1	1999	Glucosylceramide synthase (GCS) catalyzes the transfer of glucose from UDP-glucose to ceramide to form glucosylceramide, the precursor of most higher order glycosphingolipids.	Uridine Diphosphate Glucose	71-82	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	0-25
9867864-1	1999	Glucosylceramide synthase (GCS) catalyzes the transfer of glucose from UDP-glucose to ceramide to form glucosylceramide, the precursor of most higher order glycosphingolipids.	Uridine Diphosphate Glucose	71-82	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	27-30
10529216-1	1999	Galactose-1-phosphate uridylyltransferase (GalT) catalyzes the reversible transformation of UDP-glucose and galactose-1-phosphate (Gal-1-P) into UDP-galactose and glucose-1-phosphate (Glc-1-P) by a double displacement mechanism, with the intermediate formation of a covalent uridylyl-enzyme (UMP-enzyme).	Uridine Diphosphate Glucose	92-103	galactose-1-phosphate uridylyltransferase	Homo sapiens	0-41
10529216-1	1999	Galactose-1-phosphate uridylyltransferase (GalT) catalyzes the reversible transformation of UDP-glucose and galactose-1-phosphate (Gal-1-P) into UDP-galactose and glucose-1-phosphate (Glc-1-P) by a double displacement mechanism, with the intermediate formation of a covalent uridylyl-enzyme (UMP-enzyme).	Uridine Diphosphate Glucose	92-103	galactose-1-phosphate uridylyltransferase	Homo sapiens	43-47
10529216-14	1999	The variant E182A-GalT displayed about half the activity of wild-type GalT, and all of the active sites underwent uridylylation to the UMP-enzyme, similar to wild-type GalT, upon reaction with UDP-Glc.	Uridine Diphosphate Glucose	193-200	galactose-1-phosphate uridylyltransferase	Homo sapiens	18-22
10362837-0	1999	The O-linked fucose glycosylation pathway: identification and characterization of a uridine diphosphoglucose: fucose-beta1,3-glucosyltransferase activity from Chinese hamster ovary cells.	Uridine Diphosphate Glucose	84-108	beta-1,3-glucosyltransferase	Cricetulus griseus	117-144
10085144-8	1999	Interestingly, UDP-glucose:ceramide glucosyltransferase-1 (GlcT-1) activity and GSL synthesis, but not SM synthesis or sphingosine generation, were found to be up-regulated by SMase treatment.	Uridine Diphosphate Glucose	15-26	UDP-glucose ceramide glucosyltransferase	Mus musculus	59-65
10037750-3	1999	The first reaction binds UDP-glucose (UDP-Glu), displaces glucose-1-phosphate (glu-1-P), and forms the UMP-GALT intermediate.	Uridine Diphosphate Glucose	25-36	galactose-1-phosphate uridylyltransferase	Homo sapiens	107-111
10037750-3	1999	The first reaction binds UDP-glucose (UDP-Glu), displaces glucose-1-phosphate (glu-1-P), and forms the UMP-GALT intermediate.	Uridine Diphosphate Glucose	38-45	galactose-1-phosphate uridylyltransferase	Homo sapiens	107-111
10204993-10	1999	Incubation of microsomes with MPA and UDP-glucose produced M-1, with MPA and UDP-glucuronic acid MPAG and M-2 were formed, while with MPA and NADPH, M-3 was observed.	Uridine Diphosphate Glucose	38-49	myoregulin	Homo sapiens	59-62
9918791-1	1998	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the first step in glycosphingolipid synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	164-175	UDP-glucose ceramide glucosyltransferase	Mus musculus	30-55
9918791-1	1998	Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the first step in glycosphingolipid synthesis, the transfer of glucose from UDP-glucose to ceramide.	Uridine Diphosphate Glucose	164-175	UDP-glucose ceramide glucosyltransferase	Mus musculus	57-63
9535914-2	1998	The properties of this and other UDP-glucose:flavonoid 3-O-glucosyltransferases, homologues of the product encoded by the maize Bronze-1 locus, are a matter of conjecture.	Uridine Diphosphate Glucose	33-44	anthocyanidin 3-O-glucosyltransferase	Zea mays	128-136
9737970-1	1998	The enzyme UDP-glucose dehydrogenase (Udpgdh) (EC 1.1.1.22) converts UDP-glucose to UDP-glucuronate, a critical component of the glycosaminoglycans, hyaluronan, chondroitin sulfate, and heparan sulfate.	Uridine Diphosphate Glucose	11-22	UDP-glucose 6-dehydrogenase	Homo sapiens	38-44
9640668-5	1998	Over-expression of PPase resulted in an accumulation of sucrose and UDP-glucose, and decreased concentrations of hexose phosphates and glycerate-3-phosphate in growing ppa 1 tubers.	Uridine Diphosphate Glucose	68-79	soluble inorganic pyrophosphatase PPA1	Solanum tuberosum	19-24
9623774-1	1998	Ceramide glucosyltransferase (EC 2.4.1.80) catalyzes the first glycosylation step of glycosphingolipid (GSL) synthesis, the transfer of glucose from UDP-Glucose to hydrophobic ceramide and generate glucosylceramide (GlcCer).	Uridine Diphosphate Glucose	149-160	UDP-glucose ceramide glucosyltransferase	Mus musculus	0-28
9535914-9	1998	It should be considered whether gene products homologous to Bronze-1 in some cases more accurately should be referred to as UDP-glucose:anthocyanidin 3-O-glucosyltransferases.	Uridine Diphosphate Glucose	124-135	anthocyanidin 3-O-glucosyltransferase	Zea mays	60-68
9349281-0	1997	UDP-glucose:sterol glucosyltransferase: cloning and functional expression in Escherichia coli.	Uridine Diphosphate Glucose	0-11	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	12-38
9536051-8	1998	We confirmed that AtRGP1 produced in Escherichia coli could be reversibly glycosylated using UDP-glucose and UDP-galactose as substrates.	Uridine Diphosphate Glucose	93-104	reversibly glycosylated polypeptide 1	Arabidopsis thaliana	18-24
9494095-5	1998	Kinetic analysis showed that EGT has broadly similar specificities for UDP-galactose and UDP-glucose (kcat/Km=1790.8 and 902.1 respectively) when ecdysone is used as the other substrate.	Uridine Diphosphate Glucose	89-100	ecdysteroid UDP-glucosyl transferase	Autographa californica nucleopolyhedrovirus	29-32
9648269-1	1997	Galactosyltransferase from bovine milk was found to be able to utilise UDP-Glc to transfer Glc onto GlcNAc and chitooligomers[-beta-GlcNAc-(1-->4)-]n, n = 2-4. beta-Glucosylated products were used in binding studies with NKR-P1A protein cloned from rat natural killer cells.	Uridine Diphosphate Glucose	71-78	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Bos taurus	0-21
9349281-2	1997	The biosynthesis of these lipids is catalyzed by the membrane-bound UDP-glucose:sterol glucosyltransferase (EC 2.4.1.173).	Uridine Diphosphate Glucose	68-79	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	80-106
9341134-4	1997	We found that AdCMV-G6Pase-treated liver cells contain significantly less glycogen and Glu-6-P, but unchanged UDP-glucose levels, relative to control cells.	Uridine Diphosphate Glucose	110-121	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	20-26
9326324-1	1997	UDP-galactose-4-epimerase (GALE) is a highly conserved enzyme that catalyzes the interconversion of UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	118-129	UDP-galactose-4-epimerase	Homo sapiens	0-25
9326324-1	1997	UDP-galactose-4-epimerase (GALE) is a highly conserved enzyme that catalyzes the interconversion of UDP-galactose and UDP-glucose.	Uridine Diphosphate Glucose	118-129	UDP-galactose-4-epimerase	Homo sapiens	27-31
9312001-5	1997	In this system, addition of a glucose donor, UDP-glucose, to the microsomes triggered glucosylation of transferrin and resulted in its cyclic interaction with calnexin and calreticulin.	Uridine Diphosphate Glucose	45-56	transferrin	Homo sapiens	103-114
9312001-5	1997	In this system, addition of a glucose donor, UDP-glucose, to the microsomes triggered glucosylation of transferrin and resulted in its cyclic interaction with calnexin and calreticulin.	Uridine Diphosphate Glucose	45-56	calnexin	Homo sapiens	159-167
9312001-5	1997	In this system, addition of a glucose donor, UDP-glucose, to the microsomes triggered glucosylation of transferrin and resulted in its cyclic interaction with calnexin and calreticulin.	Uridine Diphosphate Glucose	45-56	calreticulin	Homo sapiens	172-184
9312001-6	1997	When the folding of transferrin in microsomes was analyzed, UDP-glucose enhanced the amount of folded transferrin and reduced the disulfide-linked aggregates.	Uridine Diphosphate Glucose	60-71	transferrin	Homo sapiens	20-31
9312001-6	1997	When the folding of transferrin in microsomes was analyzed, UDP-glucose enhanced the amount of folded transferrin and reduced the disulfide-linked aggregates.	Uridine Diphosphate Glucose	60-71	transferrin	Homo sapiens	102-113
9312001-7	1997	Analysis of transferrin folding in briefly heat-treated microsomes revealed that UDP-glucose was also effective in elimination of heat-induced misfolding.	Uridine Diphosphate Glucose	81-92	transferrin	Homo sapiens	12-23
9252577-9	1997	A further reduction of flux towards UDP-Glc was achieved by deletion of the two phosphoglucomutase genes in the ugp1 conditional strain.	Uridine Diphosphate Glucose	36-43	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	112-116
9271087-13	1997	The effect of resorcinol on glucokinase translocation was partly counteracted by galactosamine, which suppresses UDP-glucose and inhibits glucuronide formation, and was mimicked by phenol and p-nitrophenol but not by p-nitrophenylglucuronide.	Uridine Diphosphate Glucose	113-124	glucokinase	Homo sapiens	28-39
9252577-12	1997	Taken altogether, these results indicate that a few percent of enzymatic activities leading to the formation of UDP-Glc appears sufficient to provide the UDP-Glc demands required for cell viability, and that the loss of function of UGP1 is lethal mainly because of the inability of yeast cells to properly form the cell wall.	Uridine Diphosphate Glucose	112-119	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	232-236
9252577-12	1997	Taken altogether, these results indicate that a few percent of enzymatic activities leading to the formation of UDP-Glc appears sufficient to provide the UDP-Glc demands required for cell viability, and that the loss of function of UGP1 is lethal mainly because of the inability of yeast cells to properly form the cell wall.	Uridine Diphosphate Glucose	154-161	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	232-236
9207152-1	1997	We purified from pea (Pisum sativum) tissue an approximately 40 kDa reversibly glycosylated polypeptide (RGP1) that can be glycosylated by UDP-Glc, UDP-Xyl, or UDP-Gal, and isolated a cDNA encoding it, apparently derived from a single-copy gene (Rgp1).	Uridine Diphosphate Glucose	139-146	reversibly glycosylated polypeptide 1	Arabidopsis thaliana	105-109
8631325-1	1996	UDP-Glc pyrophosphorylase (EC 2.7.7.9) catalyses the interconversion of MgUTP plus Glc1P and UDP-Glc plus MgPPi.	Uridine Diphosphate Glucose	0-7	GLC1P	Homo sapiens	83-88
9143336-4	1997	Although the formation of glucosylceramide was detected and characterized, several lines of evidence contradicted the assumption that UDP-glucose is the immediate glucose donor for glucosylceramide formation in plants: PDMP (DL-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol), an inhibitor of ceramide glucosyltransferase in animal tissues, did not inhibit glucosylceramide formation in bean microsomes.	Uridine Diphosphate Glucose	134-145	UDP-glucose ceramide glucosyltransferase	Homo sapiens	301-329
8901635-5	1996	An overexpressed DNA segment of the cotton celA1 gene encodes a polypeptide fragment that spans these domains and binds UDP-Glc, while a similar fragment having one of these domains deleted does not.	Uridine Diphosphate Glucose	120-127	cellulose synthase A catalytic subunit 8 [UDP-forming]-like	Gossypium hirsutum	43-48
8787686-4	1996	Determination of GS kinetic constants from muscle cells of NIDDM revealed an increased basal and insulin-stimulated Km(0.1) for UDP-glucose, a decreased insulin-stimulated Vmax(0.1) and an increased insulin-stimulated activation constant (A(0.5)) for glucose-6-phosphate.	Uridine Diphosphate Glucose	128-139	insulin	Homo sapiens	97-104
8615352-2	1996	The cellular UDPgalactose concentration has been thought to be maintained by the interconversion of UDPglucose and UDPgalactose by UDPgalactose-4-epimerase.	Uridine Diphosphate Glucose	100-110	UDP-galactose-4-epimerase	Homo sapiens	131-155
8843948-8	1996	The proteins encoded by IS10a and a second highly homologous cDNA show sequence similarity to UDP-glucose: flavonoid glucosyltransferases.	Uridine Diphosphate Glucose	94-105	scopoletin glucosyltransferase-like	Nicotiana tabacum	24-29
8709123-8	1996	Comparison of various UDP-sugars reveals that the UDP-GlcNAc translocator has lower affinity for UDP-N-acetylgalactosamine and UDP-glucose than for its cognate substrate and therefore indicates that this translocator requires both proper stereochemistry at C-4 and an aminoacetyl group at C-2.	Uridine Diphosphate Glucose	127-138	complement C4A (Rodgers blood group)	Homo sapiens	257-260
8709123-8	1996	Comparison of various UDP-sugars reveals that the UDP-GlcNAc translocator has lower affinity for UDP-N-acetylgalactosamine and UDP-glucose than for its cognate substrate and therefore indicates that this translocator requires both proper stereochemistry at C-4 and an aminoacetyl group at C-2.	Uridine Diphosphate Glucose	127-138	complement C2	Homo sapiens	289-292
8832090-0	1996	The interaction of the UDP-GLC:glycoprotein glucosyltransferase with the acceptor glycoprotein.	Uridine Diphosphate Glucose	23-30	glucosyltransferase	Glycine max	44-63
8652544-1	1996	UDP-galactose 4-epimerase from Escherichia coli contains tightly bound NAD+, which participates in catalyzing the interconversion of UDP-galactose and UDP-glucose through its redox properties.	Uridine Diphosphate Glucose	151-162	Aldehyde dehydrogenase	Escherichia coli	71-74
8567691-1	1996	We present a method for solubilizing and purifying UDP-Glc:ceramide glucosyltransferase (EC 2.4.1.80; glucosylceramide synthase (GCS) from a rat liver and present data on its substrate specificity.	Uridine Diphosphate Glucose	51-58	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	102-127
8567691-1	1996	We present a method for solubilizing and purifying UDP-Glc:ceramide glucosyltransferase (EC 2.4.1.80; glucosylceramide synthase (GCS) from a rat liver and present data on its substrate specificity.	Uridine Diphosphate Glucose	51-58	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	129-132
8567691-3	1996	GCS activity was monitored throughout purification using UDP-Glc and a fluorescent ceramide analog as substrates.	Uridine Diphosphate Glucose	57-64	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	0-3
8567691-4	1996	Purification of GCS was achieved via a two-step dye-agarose chromatography procedure using UDP-Glc to elute the enzyme.	Uridine Diphosphate Glucose	91-98	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	16-19
7551832-6	1995	The modulation of UDPglucose and UDPgalactose concentrations, occurring after the presentation of galactose to cells, as a result of the combined actions of GALT and UDPgalactose-4-epimerase, may be important in determining rates of synthesis of complex glycoconjugates.	Uridine Diphosphate Glucose	18-28	galactose-1-phosphate uridylyltransferase	Homo sapiens	157-161
7588797-2	1995	(1992) Yeast 8, 977-986] encodes UDP-glucose pyrophosphorylase (UGPase), the enzyme which catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP.	Uridine Diphosphate Glucose	128-135	UTP--glucose-1-phosphate uridylyltransferase	Solanum tuberosum	64-70
7588797-10	1995	On glucose medium, the 40-fold increase of UGPase activity was restricted to a twofold increase in the concentration of glycogen and UDP-Glc, with no significant effect on growth.	Uridine Diphosphate Glucose	133-140	UTP--glucose-1-phosphate uridylyltransferase	Solanum tuberosum	43-49
7588797-11	1995	In contrast, on galactose, the 40-fold increase in UGPase activity was accompanied by several effects, including a threefold reduction of the growth rate, a 3-5-fold increase in the concentrations of UDP-Glc, UDP-Gal and galactose 1-phosphate, a higher sensitivity to calcofluor white and an increase in the degree of protein glycosylation.	Uridine Diphosphate Glucose	200-207	UTP--glucose-1-phosphate uridylyltransferase	Solanum tuberosum	51-57
7588797-15	1995	All these alterations, induced by manipulating the UGP1 gene, are discussed in the context of the strategic position of UDP-Glc in yeast metabolism.	Uridine Diphosphate Glucose	120-127	UTP glucose-1-phosphate uridylyltransferase	Saccharomyces cerevisiae S288C	51-55
7551832-6	1995	The modulation of UDPglucose and UDPgalactose concentrations, occurring after the presentation of galactose to cells, as a result of the combined actions of GALT and UDPgalactose-4-epimerase, may be important in determining rates of synthesis of complex glycoconjugates.	Uridine Diphosphate Glucose	18-28	UDP-galactose-4-epimerase	Homo sapiens	166-190
7752907-2	1995	As a result, great interest has been generated in the accurate assessment of UDPgalactose, as well as UDPglucose, from which UDPgalactose may be derived by the function of a ubiquitous, active UDPgalactose-4-epimerase.	Uridine Diphosphate Glucose	102-112	UDP-galactose-4-epimerase	Homo sapiens	193-217
7766040-4	1995	The membrane preparations also catalysed the transformation of UDP-glucose into labelled low-molecular-weight products, mainly glucose (by phosphatase action), glucose-1-phosphate (by phosphodiesterase action) and glyco(phospho)lipids (by glycosyltransferase action).	Uridine Diphosphate Glucose	63-74	pglcat8	Hordeum vulgare	239-258
7868856-4	1995	Uridine diphosphoglucose dehydrogenase (UDPGD) activity is responsible for the prior conversion of UDP-glucose to UDP-glucuronate.	Uridine Diphosphate Glucose	99-110	UDP-glucose 6-dehydrogenase	Homo sapiens	0-38
7868856-4	1995	Uridine diphosphoglucose dehydrogenase (UDPGD) activity is responsible for the prior conversion of UDP-glucose to UDP-glucuronate.	Uridine Diphosphate Glucose	99-110	UDP-glucose 6-dehydrogenase	Homo sapiens	40-45
7867779-4	1995	CDP-glucose is utilized at 70% of the rate of UDP-glucose.	Uridine Diphosphate Glucose	46-57	cut like homeobox 1	Homo sapiens	0-3
7982990-3	1994	The pure yeast glucosyltransferase formed protein-linked Glc1-Man9GlcNAc2,Glc1Man8GlcNAc2, and Glc1Man7GlcNAc2 when incubated with UDP-Glc and denatured thyroglobulin.	Uridine Diphosphate Glucose	131-138	GTPase-activating protein IRA1	Saccharomyces cerevisiae S288C	57-61
8086032-7	1994	The excessive growth could be blocked by PDMP, which competes with UDP-glc for binding to glucosylceramide synthase.	Uridine Diphosphate Glucose	67-74	UDP-glucose ceramide glucosyltransferase	Homo sapiens	90-115
8163481-2	1994	Pyrimidine nucleotides stimulated inositol phosphate accumulation with an order of potency of UDP > 5-BrUTP > UTP > dTDP > UDP glucose.	Uridine Diphosphate Glucose	135-146	TAR DNA-binding protein-43 homolog	Drosophila melanogaster	125-129
8076653-5	1994	Overexpression of Alg5p in both yeast and Escherichia coli results in an increase of UDP-glucose:dolichyl-phosphate glucosyltransferase activity, whereas a deletion of the yeast gene leads to a loss of this activity and a concomitant underglycosylation of carboxypeptidase Y.	Uridine Diphosphate Glucose	85-96	dolichyl-phosphate beta-glucosyltransferase	Saccharomyces cerevisiae S288C	18-23
12232266-1	1994	Membrane-bound UDP-glucose:sterol [beta]-D-glucosyltransferase (UDPG-SGTase) catalyzes the formation of steryl glucosides from UDP-glucose and free sterols.	Uridine Diphosphate Glucose	15-26	UDP-glucose pyrophosphorylase 2	Homo sapiens	64-68
12232266-1	1994	Membrane-bound UDP-glucose:sterol [beta]-D-glucosyltransferase (UDPG-SGTase) catalyzes the formation of steryl glucosides from UDP-glucose and free sterols.	Uridine Diphosphate Glucose	127-138	UDP-glucose pyrophosphorylase 2	Homo sapiens	64-68
8373190-0	1993	Purification and properties of UDP-glucose:thiohydroximate glucosyltransferase from Brassica napus L. seedlings.	Uridine Diphosphate Glucose	31-42	UDP-glycosyltransferase 72B1-like	Brassica napus	59-78
1765099-10	1991	5"-nucleotidase isolated from Torpedo electric organ hydrolyzes UDP-glucose at 8% of the rate of AMP hydrolysis.	Uridine Diphosphate Glucose	64-75	5'-nucleotidase ecto	Homo sapiens	0-15
12231791-4	1993	SA and GSA accumulation in the TMV-inoculated leaf paralleled the increase in the activity of a UDP-glucose:salicylic acid 3-O-glucosyltransferase (EC 2.4.1.35) ([beta]-GTase) capable of converting SA to GSA.	Uridine Diphosphate Glucose	96-107	GNAS complex locus	Homo sapiens	204-207
12231759-7	1993	However, Lineweaver-Burk plots for the substrates glucose-1-P and UTP were biphasic in nature when UGPase was assayed in the direction of UDP-glucose synthesis.	Uridine Diphosphate Glucose	138-149	UTP--glucose-1-phosphate uridylyltransferase	Solanum tuberosum	99-105
8467996-4	1993	Complementation studies with E. coli galU mutants showed that the TPS1-encoded trehalose-6-phosphate synthase is UDP-glucose-dependent.	Uridine Diphosphate Glucose	113-124	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	66-70
8430777-7	1993	CGRP inhibited insulin-stimulated glycogen synthase in skeletal muscle with a 50% effective dose of 1.9 +/- 0.36 x 10(-10) M. This effect on glycogen synthase was due to a reduction in enzyme affinity for UDP-glucose, with no changes in the maximal velocity.	Uridine Diphosphate Glucose	205-216	calcitonin-related polypeptide alpha	Rattus norvegicus	0-4
8220487-1	1993	Sucrose synthase, an important enzyme in carbohydrate metabolism, catalyzes the reversible conversion of sucrose and UDP to UDP-glucose and fructose in vitro.	Uridine Diphosphate Glucose	124-135	sucrose synthase 2	Arabidopsis thaliana	0-16
1744121-4	1991	Photoincorporation of [beta-32P]5-N3UDP-GlcA into bovine liver UDP-Glc dehydrogenase (EC 1.1.1.22) was saturable with an apparent Kd of 12.5 microM, and was inhibited by the known active-site effectors UDP-GlcA, UDP-Glc, and UDP-xylose.	Uridine Diphosphate Glucose	36-43	UDP-glucose 6-dehydrogenase	Bos taurus	63-84
2144831-2	1990	The removal of phospholipids completely abolished the activity of the enzyme UDP-glucose:ceramide glucosyltransferase from Golgi membranes.	Uridine Diphosphate Glucose	77-88	UDP-glucose ceramide glucosyltransferase	Homo sapiens	89-117
2080308-0	1990	[Uridine diphosphate glucose (UDPG) in the treatment of hepatic disease from chronic alcohol abuse].	Uridine Diphosphate Glucose	1-28	UDP-glucose pyrophosphorylase 2	Homo sapiens	30-34
24221516-5	1988	Uridine 5"-diphosphate (UDP)-glucose, UDP-galactose, but not UDP-mannose and the pertinent sugars, dissipate the ATP-generated pH gradient (k 1/2 10-20 mM UDP-glucose; optimum pH at 7.8).	Uridine Diphosphate Glucose	0-36	keratin 1	Homo sapiens	140-151
34840926-6	2021	Similarly, nucleotides such as Adenosine tri-phosphate (ATP), Adenosine di-phosphate (ADP), Uridine tri-phosphate (UTP), Uridine di-phosphate (UDP) and Uridine diphosphoglucose (UDPG) induced elevated reactive oxygen species (ROS) and tartrate Resistant Acid Phosphatase (TRAP) activity in RAW264.7 cells.	Uridine Diphosphate Glucose	152-176	acid phosphatase 5, tartrate resistant	Mus musculus	235-270
34840926-6	2021	Similarly, nucleotides such as Adenosine tri-phosphate (ATP), Adenosine di-phosphate (ADP), Uridine tri-phosphate (UTP), Uridine di-phosphate (UDP) and Uridine diphosphoglucose (UDPG) induced elevated reactive oxygen species (ROS) and tartrate Resistant Acid Phosphatase (TRAP) activity in RAW264.7 cells.	Uridine Diphosphate Glucose	152-176	acid phosphatase 5, tartrate resistant	Mus musculus	272-276
34840926-6	2021	Similarly, nucleotides such as Adenosine tri-phosphate (ATP), Adenosine di-phosphate (ADP), Uridine tri-phosphate (UTP), Uridine di-phosphate (UDP) and Uridine diphosphoglucose (UDPG) induced elevated reactive oxygen species (ROS) and tartrate Resistant Acid Phosphatase (TRAP) activity in RAW264.7 cells.	Uridine Diphosphate Glucose	178-182	acid phosphatase 5, tartrate resistant	Mus musculus	235-270
34840926-8	2021	ATP, ADP, UTP, UDP and UDPG also induced osteoclastogenesis as evident from fused multinucleate cells and expression of osteoclast markers (TRAP, Cathepsin K (CTSK)) as determined by Q-PCR.	Uridine Diphosphate Glucose	23-27	acid phosphatase 5, tartrate resistant	Mus musculus	140-144
34840926-8	2021	ATP, ADP, UTP, UDP and UDPG also induced osteoclastogenesis as evident from fused multinucleate cells and expression of osteoclast markers (TRAP, Cathepsin K (CTSK)) as determined by Q-PCR.	Uridine Diphosphate Glucose	23-27	cathepsin K	Mus musculus	146-157
34840926-8	2021	ATP, ADP, UTP, UDP and UDPG also induced osteoclastogenesis as evident from fused multinucleate cells and expression of osteoclast markers (TRAP, Cathepsin K (CTSK)) as determined by Q-PCR.	Uridine Diphosphate Glucose	23-27	cathepsin K	Mus musculus	159-163
34657041-7	2022	UDP-Glc activates P2Y14 in A-ICs and triggers the production of chemokines that attract pro-inflammatory immune cells into the kidney stroma and aggravate ischemia-induced proximal tubule injury.	Uridine Diphosphate Glucose	0-7	purinergic receptor P2Y14	Homo sapiens	18-23
34155714-3	2021	This weak but well-resolved signal lies 0.9 ppm upfield of UDP(G) Pbeta-multiplet from a mixture of UDP-Glc, UDP-Gal, UDP-GlcNAc and UDP-GalNAc.	Uridine Diphosphate Glucose	100-107	UDP-glucose pyrophosphorylase 2	Homo sapiens	59-65
3371347-2	1988	UDP-glucose is an R-state inhibitor of glycogen phosphorylase b, competitive with the substrate, glucose 1-phosphate and noncompetitive with the allosteric activator, AMP.	Uridine Diphosphate Glucose	0-11	glycogen phosphorylase B	Homo sapiens	39-63
2524552-0	1989	Regulation of UDP-galactose:ceramide galactosyltransferase and UDP-glucose:ceramide glucosyltransferase after crush and transection nerve injury.	Uridine Diphosphate Glucose	63-74	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	75-103
24221516-5	1988	Uridine 5"-diphosphate (UDP)-glucose, UDP-galactose, but not UDP-mannose and the pertinent sugars, dissipate the ATP-generated pH gradient (k 1/2 10-20 mM UDP-glucose; optimum pH at 7.8).	Uridine Diphosphate Glucose	155-166	keratin 1	Homo sapiens	140-151
24221516-7	1988	UDP-glucoseinduced Pi release from the GV saturates (k 1/2=1 mM UDP-glucose; optimum pH at 7) and is completely inhibited by the anion-channel blocker 4,4"-diisothiocyano-2,2"-stilbene disulfonic acid (DIDS;k 1/2=140 muM).	Uridine Diphosphate Glucose	0-11	keratin 1	Homo sapiens	53-56
24221516-7	1988	UDP-glucoseinduced Pi release from the GV saturates (k 1/2=1 mM UDP-glucose; optimum pH at 7) and is completely inhibited by the anion-channel blocker 4,4"-diisothiocyano-2,2"-stilbene disulfonic acid (DIDS;k 1/2=140 muM).	Uridine Diphosphate Glucose	0-11	keratin 1	Homo sapiens	207-210
3031074-1	1987	UDP-glucose:glycoprotein glucose-1-phosphotransferase (Glc-phosphotransferase) catalyzes the transfer of alpha Glc-1-P from UDP-Glc to endoglycosidase H-sensitive oligosaccharides on acceptor glycoproteins.	Uridine Diphosphate Glucose	0-11	GLC1P	Homo sapiens	111-118
2823902-1	1987	The beta-phosphoro[35S]thioate analogue of UDP-glucose ((beta-35S)UDP-Glc) is utilized with approximately the same efficiency as the parent compound by the UDP-glucose:glycoprotein glucose-1-phosphotransferase (glucosyltransferase), which catalyzes the transfer of alpha Glc-1-P from UDP-Glc to mannose-containing oligosaccharides on acceptor glycoproteins.	Uridine Diphosphate Glucose	43-54	GLC1P	Homo sapiens	271-278
2823902-1	1987	The beta-phosphoro[35S]thioate analogue of UDP-glucose ((beta-35S)UDP-Glc) is utilized with approximately the same efficiency as the parent compound by the UDP-glucose:glycoprotein glucose-1-phosphotransferase (glucosyltransferase), which catalyzes the transfer of alpha Glc-1-P from UDP-Glc to mannose-containing oligosaccharides on acceptor glycoproteins.	Uridine Diphosphate Glucose	156-167	GLC1P	Homo sapiens	271-278
2823902-1	1987	The beta-phosphoro[35S]thioate analogue of UDP-glucose ((beta-35S)UDP-Glc) is utilized with approximately the same efficiency as the parent compound by the UDP-glucose:glycoprotein glucose-1-phosphotransferase (glucosyltransferase), which catalyzes the transfer of alpha Glc-1-P from UDP-Glc to mannose-containing oligosaccharides on acceptor glycoproteins.	Uridine Diphosphate Glucose	66-73	GLC1P	Homo sapiens	271-278
3357416-5	1988	In this study we apply the technique to explore whether the enzyme UDP-galactose-4-epimerase catalyzing the step UDP-galactose to UDP-glucose is nonequilibrium and therefore potentially has a regulatory role for utilization of free galactose.	Uridine Diphosphate Glucose	130-141	UDP-galactose-4-epimerase	Rattus norvegicus	67-92
2962852-2	1988	1) Intracellular levels of the glycogen precursor UDP-glucose decreased 17-18% (P less than 0.01) within 30 min of insulin addition.	Uridine Diphosphate Glucose	50-61	insulin	Bos taurus	115-122
3031074-1	1987	UDP-glucose:glycoprotein glucose-1-phosphotransferase (Glc-phosphotransferase) catalyzes the transfer of alpha Glc-1-P from UDP-Glc to endoglycosidase H-sensitive oligosaccharides on acceptor glycoproteins.	Uridine Diphosphate Glucose	124-131	GLC1P	Homo sapiens	111-118
3031074-2	1987	We have previously demonstrated that Glc-phosphotransferase was specific for UDP-Glc as its nucleotide sugar substrate and thus appeared to be distinct from UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase), an enzyme specific for lysosomally destined acceptor glycoproteins.	Uridine Diphosphate Glucose	77-84	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta	Homo sapiens	236-261
2941300-6	1986	A beta-elimination reaction carried out in the presence of a reducing agent demonstrated that only one glucosyl moiety is transferred from UDP-Glc to the aminoacyl residue, thus forming an O-glucosidic linkage.	Uridine Diphosphate Glucose	139-146	amyloid beta precursor protein	Homo sapiens	0-6
2819807-1	1987	The synthesis of uridine diphosphate glucose (UDPG), cytidine diphosphate choline (CDP-choline), glucose-1-phosphate (G1P) and glucose-6-phosphate (G6P) has been accomplished under simulated prebiotic conditions using urea and cyanamide, two condensing agents considered to have been present on the primitive Earth.	Uridine Diphosphate Glucose	46-50	UDP-glucose pyrophosphorylase 2	Homo sapiens	17-44
6518414-6	1984	However, the specific activity of UTP and the labeled amounts of UDP-glucose in erythropoietin-treated cells were not significantly different from those in control cell cultures.	Uridine Diphosphate Glucose	65-76	erythropoietin	Bos taurus	80-94
6242442-1	1984	The control of glycosaminoglycan biosynthesis was investigated by studying the kinetic and regulatory properties of some enzymes involved in the formation of UDP-sugar precursors: UDP-N-acetylglucosamine 4"-epimerase, catalyzing the interconversion of hexosamine precursors and UDP-glucose dehydrogenase and UDP-glucose 4"-epimerase, utilizing UDP-glucose for the formation of uronic acid and galactose precursors.	Uridine Diphosphate Glucose	278-289	UDP-galactose-4-epimerase	Bos taurus	180-216
6228260-6	1983	This is shown by the different effect obtained with two UDP-Glc utilizing membrane-bound enzymes : UDP-Glc : phospho-dolichyl glucosyltransferase and UDP-Glc : ceramide glucosyltransferase : the first one not being affected but the second one being markedly inhibited under the same condition, although both are inhibited when the membrane environment is disturbed by detergent.	Uridine Diphosphate Glucose	56-63	UDP-glucose ceramide glucosyltransferase	Rattus norvegicus	160-188
6242442-5	1984	At the level of UDP-glucose utilization two other control mechanisms were demonstrated: the different affinities of UDP-glucose dehydrogenase and UDP-glucose 4"-epimerase for UDP-glucose in tissues with different glycosaminoglycan production and the cellular concentration of UDP-xylose.	Uridine Diphosphate Glucose	16-27	UDP-glucose 6-dehydrogenase	Bos taurus	116-141
6242442-5	1984	At the level of UDP-glucose utilization two other control mechanisms were demonstrated: the different affinities of UDP-glucose dehydrogenase and UDP-glucose 4"-epimerase for UDP-glucose in tissues with different glycosaminoglycan production and the cellular concentration of UDP-xylose.	Uridine Diphosphate Glucose	16-27	UDP-galactose-4-epimerase	Bos taurus	146-170
6460849-2	1981	The enzymatic assay for CGalT in cultured glial cells was complicated by a rapid conversion of UDP-galactose to UDP-glucose, due to the elevated UDP-galactose-4"-epimerase activity in certain glial cell clones.	Uridine Diphosphate Glucose	112-123	UDP-galactose-4-epimerase	Rattus norvegicus	145-171
6811701-6	1982	Activity of the control enzyme UDP-glucose:ceramide glucosyltransferase was always normal in both the spinal cord and kidney.	Uridine Diphosphate Glucose	31-42	UDP-glucose ceramide glucosyltransferase	Homo sapiens	43-71
6579571-5	1983	Production of thromboxane and hydroxy fatty acids was reduced in thrombin-aggregated washed platelets preincubated with URI-73A.	Uridine Diphosphate Glucose	120-123	coagulation factor II, thrombin	Homo sapiens	65-73
437116-0	1979	Loss of C-5 hydrogen during oxidation of UDP-D-glucose by UDP-D-glucose dehydrogenase.	Uridine Diphosphate Glucose	41-54	complement C5	Homo sapiens	8-11
6247691-5	1980	The variant galactose-1-phosphate uridylyltransferase was further characterized by a lowered affinity towards galactose 1-phosphate, non-Michaelis-Menten kinetics towards UDP-glucose, an increased thermal stability, and complete inactivity upon Cellogel electrophoresis.	Uridine Diphosphate Glucose	171-182	galactose-1-phosphate uridylyltransferase	Homo sapiens	12-53
870083-1	1977	Glucokinase, phosphoglucomutase and glucose-1-phosphate uridylyltransferase are the three enzymes involved in a microsomic pathway for the synthesis of UDP glucose.	Uridine Diphosphate Glucose	152-163	glucokinase	Rattus norvegicus	0-11
223665-5	1978	It also contains the three enzymes implicated in the biosynthetic pathway for UDP-glucose (glucokinase, phosphoglucomutase and UTP : glucose-1-phosphate uridylyltransferase).	Uridine Diphosphate Glucose	78-89	glucokinase	Homo sapiens	91-102
223665-5	1978	It also contains the three enzymes implicated in the biosynthetic pathway for UDP-glucose (glucokinase, phosphoglucomutase and UTP : glucose-1-phosphate uridylyltransferase).	Uridine Diphosphate Glucose	78-89	UDP-glucose pyrophosphorylase 2	Homo sapiens	127-172
16659924-6	1977	This effect can be explained by the conversion of uridine triphosphate to UDP-glucose by UDP-glucose pyrophosphorylase, thereby raising substrate concentration to the activating range.	Uridine Diphosphate Glucose	74-85	UTP--glucose-1-phosphate uridylyltransferase	Gossypium hirsutum	89-118
557038-2	1977	The oxidation of UDP-glucose by the enzyme UDP-glucose dehydrogenase (EC 1.1.1.22) from beef liver has been shown to proceed via the enzyme-bound intermediate, UDP-alpha-D-glyco-hexodialdose.	Uridine Diphosphate Glucose	17-28	UDP-glucose 6-dehydrogenase	Homo sapiens	43-68
1023336-1	1976	In the byosinthesis of glycosaminoglycans, UDP-glucose is utilized by two enzymes: UDP-glucose dehydrogenase which produces UDP-glucuronic acid (chondroitin sulphate precursor), and UDP-glucose 4"-epimerase which produces UDP-galactose (keratan sulphate precursor).	Uridine Diphosphate Glucose	43-54	UDP-glucose 6-dehydrogenase	Homo sapiens	83-108
932002-17	1976	Monsaccharides (N-acetylglucosamine and glucose) strongly enhance the binding of alpha-lactalbumin to enzyme complexes containing Mn2+, in the presence or absence of UDP-glucose.	Uridine Diphosphate Glucose	166-177	lactalbumin alpha	Bos taurus	81-98
818085-3	1976	Inhibition patterns with N-acetylglucosamine or UDP-glucose as inhibitors of the galactosylation of ovalbumin indicated that either UDP-galactose or N-acetylglucosamine can bind to an enzyme-Mn2+ complex by a random equilibrium mechanism.	Uridine Diphosphate Glucose	48-59	ovalbumin	Bos taurus	100-109
1023336-1	1976	In the byosinthesis of glycosaminoglycans, UDP-glucose is utilized by two enzymes: UDP-glucose dehydrogenase which produces UDP-glucuronic acid (chondroitin sulphate precursor), and UDP-glucose 4"-epimerase which produces UDP-galactose (keratan sulphate precursor).	Uridine Diphosphate Glucose	43-54	UDP-galactose-4-epimerase	Homo sapiens	182-206
1023336-9	1976	Under our experimental conditions, UDP-glucose 4"-epimerase present in the cells epimerizes UDP-galactose (added in the incubation mixture) to UDP-glucose which can bo oxidized by the excess of UDP-glucose dehydrogenase to UDP-glucuronic acid with a consequent NADH formation.	Uridine Diphosphate Glucose	35-46	UDP-glucose 6-dehydrogenase	Homo sapiens	194-219
239676-2	1975	UDP-xylose and UDP-glucose both bind to UDP-glucose dehydrogenase in the absence of NAD+, causing an enhancement of protein fluorescence.	Uridine Diphosphate Glucose	15-26	UDP-glucose 6-dehydrogenase	Homo sapiens	40-65
1174541-2	1975	Analogs of uridine diphosphate glucose (UDPGlc) with a modified hexosyl residue which contained a deoxy-unit at C-3 or C-4 were tested as substrates of calf liver UDPGlc dehydrogenase (EC 1.1.1.22).	Uridine Diphosphate Glucose	11-38	complement C3	Bos taurus	112-115
1174541-2	1975	Analogs of uridine diphosphate glucose (UDPGlc) with a modified hexosyl residue which contained a deoxy-unit at C-3 or C-4 were tested as substrates of calf liver UDPGlc dehydrogenase (EC 1.1.1.22).	Uridine Diphosphate Glucose	11-38	complement C4	Bos taurus	119-122
1174541-2	1975	Analogs of uridine diphosphate glucose (UDPGlc) with a modified hexosyl residue which contained a deoxy-unit at C-3 or C-4 were tested as substrates of calf liver UDPGlc dehydrogenase (EC 1.1.1.22).	Uridine Diphosphate Glucose	11-38	UDP-glucose 6-dehydrogenase	Bos taurus	163-183
1177668-0	1975	Enzymatic synthesis of glucocerebroside by UDP-glucose: ceramide glucosyltransferase during ontogenesis of chicken retina.	Uridine Diphosphate Glucose	43-54	UDP-glucose ceramide glucosyltransferase	Gallus gallus	56-84
24481791-1	1972	The activity of two enzymes of the UDP-glucose and UDP-galactose biosynthetic pathway-phosphoglucose-isomerase and phosphoglucomutase-have been followed during morphogenesis of the unicellular green alga Acetabularia mediterranea.	Uridine Diphosphate Glucose	35-46	glucose-6-phosphate isomerase	Oryctolagus cuniculus	86-110
126129-8	1975	The physiological meaning of UDP-glucose 4"-epimerase in glycosaminoglycan biosynthesis in the two tissues under study is discussed on the basis of the Km values of UDP-glucose 4"-epimerase and UDP-glucose dehydrogenase and on the basis of the rate of UDP-glucose and UDP-galactose utilization.	Uridine Diphosphate Glucose	29-40	UDP-galactose-4-epimerase	Bos taurus	165-189
126129-8	1975	The physiological meaning of UDP-glucose 4"-epimerase in glycosaminoglycan biosynthesis in the two tissues under study is discussed on the basis of the Km values of UDP-glucose 4"-epimerase and UDP-glucose dehydrogenase and on the basis of the rate of UDP-glucose and UDP-galactose utilization.	Uridine Diphosphate Glucose	29-40	UDP-glucose 6-dehydrogenase	Bos taurus	194-219
1138993-3	1975	Enzymic oxidation of UDP-glucose-6-3-H with calf liver UDP-glucose dehydrogenase was found to proceed with direct transfer of the hydrogen from C-6 of UDP-glucose onto NAD.	Uridine Diphosphate Glucose	21-32	UDP-glucose 6-dehydrogenase	Bos taurus	55-80
5783975-1	1969	An alkali-insoluble glucan synthesized from UDP-d-glucose by the particulate enzyme system from Phaseolus aureus is hydrolyzed by a highly purified exo-beta-(1 --> 3)-d-glucanase to d-glucose, to the extent of 91% in 24 hr.	Uridine Diphosphate Glucose	44-57	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	152-159
16658176-0	1972	The Formation of beta, 1 --> 4 Glucan from UDP-alpha-d-Glucose Catalyzed by a Phaseolus aureus Enzyme.	Uridine Diphosphate Glucose	46-65	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	17-24
16658176-4	1972	The presence or absence of beta, 1 --> 4 glucan synthetase activity was independent of tissue source, substrate concentration, or homogenization method.The particulate enzyme also catalyzes the formation of a beta, 1 --> 3 linked glucan from UDP-d glucose which is usually soluble in hot alkali.	Uridine Diphosphate Glucose	248-261	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	27-34
16658176-4	1972	The presence or absence of beta, 1 --> 4 glucan synthetase activity was independent of tissue source, substrate concentration, or homogenization method.The particulate enzyme also catalyzes the formation of a beta, 1 --> 3 linked glucan from UDP-d glucose which is usually soluble in hot alkali.	Uridine Diphosphate Glucose	248-261	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	212-219
5990224-0	1966	[Uridine-diphosphoglucose (UDPG) in the therapy of viral hepatitis].	Uridine Diphosphate Glucose	1-25	UDP-glucose pyrophosphorylase 2	Homo sapiens	27-31
16656496-2	1967	The neutral polymer derived from uridine diphosphate glucose utilization yielded, after cellulase digestion, mostly cellobiose and to a lesser extent a substance tentatively identified as a mixed-linkage beta1,4 = beta1,3-trisaccharide; only cellobiose was found after guanosine diphosphate glucose utilization.	Uridine Diphosphate Glucose	33-60	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	204-211
16656496-2	1967	The neutral polymer derived from uridine diphosphate glucose utilization yielded, after cellulase digestion, mostly cellobiose and to a lesser extent a substance tentatively identified as a mixed-linkage beta1,4 = beta1,3-trisaccharide; only cellobiose was found after guanosine diphosphate glucose utilization.	Uridine Diphosphate Glucose	33-60	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	214-221
33792561-7	2021	However, UDP-G increased chemokinesis in eosinophils and enhanced their response to the eosinophil chemoattractant, CCL24.	Uridine Diphosphate Glucose	9-14	chemokine (C-C motif) ligand 24	Mus musculus	116-121
33171387-1	2021	UDP-glucose 4-epimerase (GalE) catalyzes the interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal) and/or the interconversion of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc) in sugar metabolism.	Uridine Diphosphate Glucose	77-84	UDP-galactose-4-epimerase	Homo sapiens	0-23
33171387-1	2021	UDP-glucose 4-epimerase (GalE) catalyzes the interconversion of UDP-glucose (UDP-Glc) and UDP-galactose (UDP-Gal) and/or the interconversion of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc) in sugar metabolism.	Uridine Diphosphate Glucose	77-84	UDP-galactose-4-epimerase	Homo sapiens	25-29
32858085-7	2020	However, HUGT1 remarkably accelerated the folding of M9GN2-RNase in the presence of UDP-Glc.	Uridine Diphosphate Glucose	84-91	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	9-14
33729990-3	2021	Here we report crystal structures of the catalytic domain of Arabidopsis thaliana CESA3 (AtCESA3CatD) in both apo and uridine diphosphate (UDP)-glucose (UDP-Glc)-bound forms.	Uridine Diphosphate Glucose	153-160	Cellulose synthase family protein	Arabidopsis thaliana	82-87
33461462-2	2021	GSK-3 was first discovered in 1980 as a regulatory protein kinase for its namesake, Glycogen synthase (GS) enzyme, which is responsible for the conversion of glycogen from glucose with the help of uridine diphosphate glucose (UDP-Glu) residue.	Uridine Diphosphate Glucose	226-233	glycogen synthase kinase 3 alpha	Homo sapiens	0-5
31926981-4	2020	UGT73C5 was coupled with sucrose synthase (SuSy) from A. thaliana to regenerate costly uridine diphosphate glucose (UDPG) from cheap sucrose and catalytic amounts of uridine diphosphate (UDP).	Uridine Diphosphate Glucose	116-120	don-glucosyltransferase 1	Arabidopsis thaliana	0-7
32287042-5	2020	In addition, we show that the concentration of the P2Y14 receptor ligand, uridine diphosphate-glucose (UDP-Glc), was higher in urine samples from intensive care unit patients who developed AKI compared to patients without AKI.	Uridine Diphosphate Glucose	103-110	purinergic receptor P2Y14	Homo sapiens	51-65
32266981-2	2020	Sulfoquinovosyl diacylglycerol1 (AtSQD1) encodes a protein, which catalyzes uridine diphosphate glucose (UDPG) and sulfite (SO3 2- ) to UDP-sulfoquinovose, which is a key component in the sulfolipid biosynthetic pathway.	Uridine Diphosphate Glucose	105-109	sulfoquinovosyldiacylglycerol 1	Arabidopsis thaliana	33-39
32188137-1	2020	UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase.	Uridine Diphosphate Glucose	0-11	UDP-glucose pyrophosphorylase 2	Homo sapiens	40-44
32188137-1	2020	UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase.	Uridine Diphosphate Glucose	13-20	UDP-glucose pyrophosphorylase 2	Homo sapiens	40-44
32175296-1	2020	UDP-glucose dehydrogenase (UGDH) encodes an oxidoreductase that converts two successive oxidations of UDP-glucose to produce UDP-glucuronic acid, a key component in the synthesis of several polysaccharides such as glycosaminoglycan and the disaccharide hyaluronic acid.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	27-31
32175296-1	2020	UDP-glucose dehydrogenase (UGDH) encodes an oxidoreductase that converts two successive oxidations of UDP-glucose to produce UDP-glucuronic acid, a key component in the synthesis of several polysaccharides such as glycosaminoglycan and the disaccharide hyaluronic acid.	Uridine Diphosphate Glucose	0-11	hydroxysteroid 17-beta dehydrogenase 6	Homo sapiens	44-58
33008919-2	2020	Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as the cofactor by UGT1 and UGT2 family enzymes, UGT2B7 and several other enzymes can utilise both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the formation of glucuronide and glucoside conjugates.	Uridine Diphosphate Glucose	30-37	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	86-90
33008919-2	2020	Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as the cofactor by UGT1 and UGT2 family enzymes, UGT2B7 and several other enzymes can utilise both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the formation of glucuronide and glucoside conjugates.	Uridine Diphosphate Glucose	30-37	UDP-glucose glycoprotein glucosyltransferase 2	Homo sapiens	95-99
33008919-2	2020	Although UDP-glucuronic acid (UDP-GlcUA) is most commonly employed as the cofactor by UGT1 and UGT2 family enzymes, UGT2B7 and several other enzymes can utilise both UDP-GlcUA and UDP-glucose (UDP-Glc), leading to the formation of glucuronide and glucoside conjugates.	Uridine Diphosphate Glucose	30-37	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	116-122
33008919-3	2020	An investigation of UGT2B7 catalysed morphine glycosidation indicated that glucuronidation is the principal route of metabolism because the binding affinity of UDP-GlcUA is higher than that of UDP-Glc.	Uridine Diphosphate Glucose	160-167	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	20-26
31836608-6	2020	The Vmax/Km ratios for UGT3A2 activity with UDP-xylose vs. UDP-glucose as cosubstrate ranged from 0.71-4.0 for all PAHs tested, demonstrating that PAH glycosylation may be occurring at rates up to four-fold higher with UDP-xylose than UDP-glucose.	Uridine Diphosphate Glucose	59-70	UDP glycosyltransferase family 3 member A2	Homo sapiens	23-29
31836608-11	2020	SIGNIFICANCE STATEMENT: UGT3A2 is highly active against PAHs with either UDP-glucose or UDP-xylose as a cosubstrate.	Uridine Diphosphate Glucose	73-84	UDP glycosyltransferase family 3 member A2	Homo sapiens	24-30
32025819-2	2020	After hydroxymethylated DNA (5hmC-DNA) was captured on the probe modified B-TiO2/ITO electrode surface through hybridization, a glycosyl can be then transferred from uridine diphosphoglucose to 5hmC-DNA and formed a covalent structure with -CH2OH in the presence of T4 beta-glucosyltransferase (beta-GT).	Uridine Diphosphate Glucose	166-190	angiotensinogen	Homo sapiens	295-302
32072977-2	2020	The action of the GALT enzyme is to convert galactose-1-phosphate and uridine diphosphate glucose into glucose-1-phosphate (G1P) and uridine diphosphate-galactose, a crucial second step of the Leloir pathway.	Uridine Diphosphate Glucose	70-97	galactose-1-phosphate uridylyltransferase	Homo sapiens	18-22
31032956-10	2019	Extracellular UDP-glucose enhanced the phosphorylation of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38, which were both abolished by the P2Y14 receptor inhibitor (PPTN).	Uridine Diphosphate Glucose	14-25	Eph receptor B1	Rattus norvegicus	58-95
31032956-10	2019	Extracellular UDP-glucose enhanced the phosphorylation of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38, which were both abolished by the P2Y14 receptor inhibitor (PPTN).	Uridine Diphosphate Glucose	14-25	Eph receptor B1	Rattus norvegicus	97-100
31032956-10	2019	Extracellular UDP-glucose enhanced the phosphorylation of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38, which were both abolished by the P2Y14 receptor inhibitor (PPTN).	Uridine Diphosphate Glucose	14-25	mitogen-activated protein kinase 8	Rattus norvegicus	103-126
31032956-10	2019	Extracellular UDP-glucose enhanced the phosphorylation of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38, which were both abolished by the P2Y14 receptor inhibitor (PPTN).	Uridine Diphosphate Glucose	14-25	mitogen-activated protein kinase 8	Rattus norvegicus	128-131
31032956-10	2019	Extracellular UDP-glucose enhanced the phosphorylation of extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38, which were both abolished by the P2Y14 receptor inhibitor (PPTN).	Uridine Diphosphate Glucose	14-25	mitogen activated protein kinase 14	Rattus norvegicus	138-141
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	interleukin 1 beta	Rattus norvegicus	179-196
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	interleukin 1 beta	Rattus norvegicus	198-206
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	C-C motif chemokine ligand 2	Rattus norvegicus	222-226
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	C-C motif chemokine ligand 2	Rattus norvegicus	228-232
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	Eph receptor B1	Rattus norvegicus	320-323
31032956-11	2019	Furthermore, quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay demonstrated that extracellular UDP-glucose significantly enhanced interleukin-1beta (IL-1beta) and chemokine CCL2 (CCL2) release, which was abolished by PPTN and significantly decreased by inhibitors of MEK/ERK (U0126) and p38 (SB202190).	Uridine Diphosphate Glucose	144-155	mitogen activated protein kinase 14	Rattus norvegicus	336-339
31243371-0	2019	UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.	Uridine Diphosphate Glucose	0-11	snail family transcriptional repressor 1	Homo sapiens	24-29
31366978-2	2019	UDP-glucose 4-epimerase (GalE) from Bifidobacterium longum (bGalE) catalyzes epimerization reactions of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with the same level of activity that is required to send galacto-hexoses into glycolysis.	Uridine Diphosphate Glucose	117-124	UDP-galactose-4-epimerase	Homo sapiens	0-23
31366978-2	2019	UDP-glucose 4-epimerase (GalE) from Bifidobacterium longum (bGalE) catalyzes epimerization reactions of UDP-Gal into UDP-Glc and UDP-GalNAc into UDP-GlcNAc with the same level of activity that is required to send galacto-hexoses into glycolysis.	Uridine Diphosphate Glucose	117-124	UDP-galactose-4-epimerase	Homo sapiens	25-29
31243371-4	2019	UDP-glucose 6-dehydrogenase (UGDH) is a key enzyme in the uronic acid pathway, and converts UDP-glucose to UDP-glucuronic acid4.	Uridine Diphosphate Glucose	0-11	UDP-glucose 6-dehydrogenase	Homo sapiens	29-33
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	67-78	UDP-glucose 6-dehydrogenase	Homo sapiens	15-19
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	UDP-glucose 6-dehydrogenase	Homo sapiens	15-19
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	ELAV like RNA binding protein 1	Homo sapiens	35-47
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	ELAV like RNA binding protein 1	Homo sapiens	49-52
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	ELAV like RNA binding protein 1	Homo sapiens	178-181
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	snail family transcriptional repressor 1	Homo sapiens	187-192
31243371-6	2019	Phosphorylated UGDH interacts with Hu antigen R (HuR) and converts UDP-glucose to UDP-glucuronic acid, which attenuates the UDP-glucose-mediated inhibition of the association of HuR with SNAI1 mRNA and therefore enhances the stability of SNAI1 mRNA.	Uridine Diphosphate Glucose	124-135	snail family transcriptional repressor 1	Homo sapiens	238-243
30247636-5	2019	GALE encodes UDP-galactose-4-epimerase, an enzyme of galactose metabolism and glycosylation responsible for two reversible reactions: interconversion of UDP-galactose with UDP-glucose and interconversion of UDP-N-acetylgalactosamine with UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	172-183	UDP-galactose-4-epimerase	Homo sapiens	0-4
31053988-3	2019	Sucrose synthase (SuSy) acts as a crucial determinant of sink strength by controlling the conversion of sucrose into UDP-glucose, which is not only the sole precursor for cellulose biosynthesis but also an extracellular signaling molecule for plants growth.	Uridine Diphosphate Glucose	117-128	sucrose synthase	Nicotiana tabacum	0-16
31053988-3	2019	Sucrose synthase (SuSy) acts as a crucial determinant of sink strength by controlling the conversion of sucrose into UDP-glucose, which is not only the sole precursor for cellulose biosynthesis but also an extracellular signaling molecule for plants growth.	Uridine Diphosphate Glucose	117-128	sucrose synthase	Nicotiana tabacum	18-22
31157175-6	2019	The donor substrate for Lic2A, UDP-galactose, is generated from UDP-glucose by UDP-galactose epimerase encoded by galE.	Uridine Diphosphate Glucose	64-75	UDP-galactose-4-epimerase	Homo sapiens	114-118
30247636-5	2019	GALE encodes UDP-galactose-4-epimerase, an enzyme of galactose metabolism and glycosylation responsible for two reversible reactions: interconversion of UDP-galactose with UDP-glucose and interconversion of UDP-N-acetylgalactosamine with UDP-N-acetylglucosamine.	Uridine Diphosphate Glucose	172-183	UDP-galactose-4-epimerase	Homo sapiens	13-38
30662936-10	2019	The luciferase reporter assay showed that miR-598 downregulated URI by directly targeting the 3" UTR of URI.	Uridine Diphosphate Glucose	64-67	microRNA 598	Homo sapiens	42-49
30457329-1	2018	Human UDP-glucose dehydrogenase (hUGDH) oxidizes UDP-glucose to UDP-glucuronic acid, an essential substrate in the phase II metabolism of drugs.	Uridine Diphosphate Glucose	6-17	UDP-glucose 6-dehydrogenase	Homo sapiens	33-38
29925073-5	2018	However, it turns out that the P2Y14 receptor in these cells responds to a molecule called uridine diphosphate (UDP)-glucose, which is a danger signal released by damaged cells anywhere in the body.	Uridine Diphosphate Glucose	112-124	purinergic receptor P2Y14	Homo sapiens	31-45
30395931-3	2018	The structures of the UGT51 and its complex with uridine diphosphate glucose (UDPG) were solved at resolutions of 2.77 A and 1.9 A, respectively.	Uridine Diphosphate Glucose	49-76	sterol 3-beta-glucosyltransferase	Saccharomyces cerevisiae S288C	22-27
30127001-4	2018	Here, we identify two novel protein O-glucosyltransferases, POGLUT2 and POGLUT3 (formerly KDELC1 and KDELC2, respectively), which transfer O-glucose (O-Glc) from UDP-Glc to serine 435.	Uridine Diphosphate Glucose	162-169	protein O-glucosyltransferase 2	Homo sapiens	90-96
30127001-4	2018	Here, we identify two novel protein O-glucosyltransferases, POGLUT2 and POGLUT3 (formerly KDELC1 and KDELC2, respectively), which transfer O-glucose (O-Glc) from UDP-Glc to serine 435.	Uridine Diphosphate Glucose	162-169	protein O-glucosyltransferase 3	Homo sapiens	101-107
29951132-13	2018	We observed that activation of P2RY14 by its ligand, UDP-glucose, resulted in selective induction of ERK1/2 phosphorylation.	Uridine Diphosphate Glucose	53-64	purinergic receptor P2Y14	Homo sapiens	31-37
29951132-13	2018	We observed that activation of P2RY14 by its ligand, UDP-glucose, resulted in selective induction of ERK1/2 phosphorylation.	Uridine Diphosphate Glucose	53-64	mitogen-activated protein kinase 3	Homo sapiens	101-107
29627573-6	2018	PtdIns(4)P inhibited UGCG activity, but not SMS activity, in a concentration-dependent manner, and UGCG activity was restored by the addition of UDP-glucose in the reaction mixture.	Uridine Diphosphate Glucose	145-156	UDP-glucose ceramide glucosyltransferase	Homo sapiens	99-103
29627573-7	2018	These results indicate that PtdIns(4)P inhibits UGCG activity by competing with UDP-glucose.	Uridine Diphosphate Glucose	80-91	UDP-glucose ceramide glucosyltransferase	Homo sapiens	48-52
29189936-8	2018	Selective P2Y14 receptor activation with UDP-glucose (UDPG) did not affect IL-6 levels in either cell type cultured alone, but in transwell cultures, UDPG decreased IL-6 protein levels in the medium.	Uridine Diphosphate Glucose	41-52	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	10-15
29660366-4	2018	Here we provide a comprehensive overview of ligands for the subgroup of the P2YR family that is activated by uracil nucleotides: P2Y2 (UTP, also ATP and dinucleotides), P2Y4 (UTP), P2Y6 (UDP), and P2Y14 (UDP, UDP-glucose, UDP-galactose).	Uridine Diphosphate Glucose	209-220	purinergic receptor P2Y2	Homo sapiens	129-133
29660366-4	2018	Here we provide a comprehensive overview of ligands for the subgroup of the P2YR family that is activated by uracil nucleotides: P2Y2 (UTP, also ATP and dinucleotides), P2Y4 (UTP), P2Y6 (UDP), and P2Y14 (UDP, UDP-glucose, UDP-galactose).	Uridine Diphosphate Glucose	209-220	purinergic receptor P2Y14	Homo sapiens	197-202
29569779-4	2018	The second pathway involves sucrose hydrolysis by cytosolic invertase (CINV), conversion of glucose to glucose-6-phosphate and glucose-1-phosphate, and UDP-glucose generation by UDP-glucose pyrophosphorylase (UGP).	Uridine Diphosphate Glucose	152-163	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	178-207
29569779-12	2018	Biochemical and imaging data demonstrate that cinv1 cinv2 seedlings are deficient in UDP-glucose production, exhibit abnormal cellulose biosynthesis and microtubule properties, and have altered cellulose organization without substantial changes to matrix polysaccharide composition, suggesting that the CINV/UGP pathway is a key metabolic route to UDP-glucose synthesis in Arabidopsis.	Uridine Diphosphate Glucose	85-96	cytosolic invertase 1	Arabidopsis thaliana	46-57
29569779-12	2018	Biochemical and imaging data demonstrate that cinv1 cinv2 seedlings are deficient in UDP-glucose production, exhibit abnormal cellulose biosynthesis and microtubule properties, and have altered cellulose organization without substantial changes to matrix polysaccharide composition, suggesting that the CINV/UGP pathway is a key metabolic route to UDP-glucose synthesis in Arabidopsis.	Uridine Diphosphate Glucose	348-359	cytosolic invertase 1	Arabidopsis thaliana	46-57
30693690-7	2018	Compared with hypoxia without any treatment, pretreatment with GPR17 agonists (LTD4, UDP, UDP-G) significantly reduced cell viability (the survival rates of cells decreased by 29.6%, 31.8% and 33.9%, all P<0.01), while the effect of GPR17 antagonist (cangrelor) was the opposite (the survival rates of cells increased by 33.2%, P<0.01).	Uridine Diphosphate Glucose	90-95	G protein-coupled receptor 17	Mus musculus	63-68
30693690-7	2018	Compared with hypoxia without any treatment, pretreatment with GPR17 agonists (LTD4, UDP, UDP-G) significantly reduced cell viability (the survival rates of cells decreased by 29.6%, 31.8% and 33.9%, all P<0.01), while the effect of GPR17 antagonist (cangrelor) was the opposite (the survival rates of cells increased by 33.2%, P<0.01).	Uridine Diphosphate Glucose	90-95	G protein-coupled receptor 17	Mus musculus	236-241
29253618-2	2018	The P2Y14 receptor is a Gi/o-coupled receptor which is activated by UDP-glucose and related sugar nucleotides.	Uridine Diphosphate Glucose	68-79	purinergic receptor P2Y14	Homo sapiens	4-18
29253618-7	2018	UDP-glucose, UDP-glucuronic acid UDP-N-acetylglucosamine (P2Y14 receptor agonists), elicited concentration-dependent contractions of the porcine coronary artery.	Uridine Diphosphate Glucose	0-11	purinergic receptor P2Y14	Homo sapiens	58-72
29253618-12	2018	Forskolin-induced VASP-phosphorylation was reduced in porcine coronary arteries exposed to UDP-glucose and MRS2690, consistent with P2Y14 receptor coupling to Gi/o proteins and inhibition of adenylyl cyclase activity.	Uridine Diphosphate Glucose	91-102	vasodilator stimulated phosphoprotein	Homo sapiens	18-22
29253618-12	2018	Forskolin-induced VASP-phosphorylation was reduced in porcine coronary arteries exposed to UDP-glucose and MRS2690, consistent with P2Y14 receptor coupling to Gi/o proteins and inhibition of adenylyl cyclase activity.	Uridine Diphosphate Glucose	91-102	purinergic receptor P2Y14	Homo sapiens	132-146
29413322-2	2018	Here we show that human NUDT22 is a Mg2+-dependent UDP-glucose and UDP-galactose hydrolase, producing UMP and glucose 1-phosphate or galactose 1-phosphate.	Uridine Diphosphate Glucose	51-62	nudix hydrolase 22	Homo sapiens	24-30
29413322-3	2018	We present the structure of human NUDT22 alone and in a complex with the substrate UDP-glucose.	Uridine Diphosphate Glucose	83-94	nudix hydrolase 22	Homo sapiens	34-40
29308528-5	2018	Moreover, the bioengineered E. coli strains with exogenous UDP-glucose biosynthetic genes and glucose facilitator diffusion protein enhanced the production of chrysin 6-C-beta-D-glucoside by approximately 1.4-fold, thus producing 10 mg/L (12%, 24 muM) and 14 mg/L (17%, 34 muM) by UGT708D1 and GtUF6CGT1, respectively, without supplementation of additional UDP-glucose in the medium.	Uridine Diphosphate Glucose	59-70	uDP-glycosyltransferase 708D1	Glycine max	281-289
29110302-5	2017	The results suggest that SUS interacts with RGP in diverse sink tissues to channel UDP-glucose derived from imported sucrose into hemicellulose and/or glycoprotein/glycolipid biosynthesis.	Uridine Diphosphate Glucose	83-94	sucrose synthase	Ricinus communis	25-28
28640934-4	2018	UGT activity using UDP-glucose as donor was then determined using 11 synthetic acceptors bearing hydroxyl, amino and thiol groups that had been shown to undergo conjugation in plant extracts.	Uridine Diphosphate Glucose	19-30	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	0-3
28926587-7	2017	In vitro glucosylation assays demonstrated that extracts from wildtype embryos contain active b3glct enzyme capable of transferring glucose from UDP-glucose to an O-fucosylated TSR, indicating functional conservation with human B3GLCT.	Uridine Diphosphate Glucose	145-156	beta 3-glucosyltransferase	Homo sapiens	94-100
28980705-14	2017	Mechanistically, UDP-Glu stimulation enhanced the activation of canonical growth signalling pathways ERK1/2 and AKT.	Uridine Diphosphate Glucose	17-24	mitogen-activated protein kinase 3	Homo sapiens	101-107
28980705-14	2017	Mechanistically, UDP-Glu stimulation enhanced the activation of canonical growth signalling pathways ERK1/2 and AKT.	Uridine Diphosphate Glucose	17-24	AKT serine/threonine kinase 1	Homo sapiens	112-115
28877911-2	2017	UDP-galactose-4-epimerase (GALE) is the last enzyme in this pathway that converts UDP-galactose to UDP-glucose and was previously identified as a downstream target of the endoplasmic reticulum (ER) stress effector spliced X-box binding protein 1, suggesting an interesting cross talk between galactose and glucose metabolism in the context of hepatic ER stress and whole-body metabolic fitness.	Uridine Diphosphate Glucose	99-110	galactose-4-epimerase, UDP	Mus musculus	0-25
28877911-2	2017	UDP-galactose-4-epimerase (GALE) is the last enzyme in this pathway that converts UDP-galactose to UDP-glucose and was previously identified as a downstream target of the endoplasmic reticulum (ER) stress effector spliced X-box binding protein 1, suggesting an interesting cross talk between galactose and glucose metabolism in the context of hepatic ER stress and whole-body metabolic fitness.	Uridine Diphosphate Glucose	99-110	galactose-4-epimerase, UDP	Mus musculus	27-31
28877911-2	2017	UDP-galactose-4-epimerase (GALE) is the last enzyme in this pathway that converts UDP-galactose to UDP-glucose and was previously identified as a downstream target of the endoplasmic reticulum (ER) stress effector spliced X-box binding protein 1, suggesting an interesting cross talk between galactose and glucose metabolism in the context of hepatic ER stress and whole-body metabolic fitness.	Uridine Diphosphate Glucose	99-110	X-box binding protein 1	Mus musculus	222-245
27670385-5	2017	Spectral fitting provided an NAD+ concentration of 107 +- 28 muM for 1 H-MRS and 367 +- 78 muM and 312 +- 65 muM for 31 P-MRS when uridine diphosphate glucose (UDPG) was excluded and included, respectively, as an overlapping signal.	Uridine Diphosphate Glucose	131-158	UDP-glucose pyrophosphorylase 2	Homo sapiens	160-164
28739255-5	2017	Moreover, the modes of inhibition of ceramide glucosyltransferase were uncompetitive with respect to both C6-NBD-cermide and UDP-glucose.	Uridine Diphosphate Glucose	125-136	UDP-glucose ceramide glucosyltransferase	Homo sapiens	37-65
28425481-3	2017	In the model organism Arabidopsis thaliana, SA glucose conjugates are formed by two homologous enzymes (UGT74F1 and UGT74F2) that transfer glucose from UDP-glucose to SA.	Uridine Diphosphate Glucose	152-163	UDP-glucosyltransferase 74F2	Arabidopsis thaliana	116-123
28752893-0	2017	The radical-SAM enzyme Viperin catalyzes reductive addition of a 5"-deoxyadenosyl radical to UDP-glucose in vitro.	Uridine Diphosphate Glucose	93-104	radical S-adenosyl methionine domain containing 2	Homo sapiens	23-30
28752893-3	2017	Here, using electron paramagnetic resonance (EPR) spectroscopy, mass spectrometry, and NMR spectroscopy, we show that uridine diphosphate glucose (UDP-glucose) is a substrate of a fungal Viperin (58% pairwise identity with human Viperin at the amino acid level) in vitro.	Uridine Diphosphate Glucose	118-145	radical S-adenosyl methionine domain containing 2	Homo sapiens	187-194
28752893-3	2017	Here, using electron paramagnetic resonance (EPR) spectroscopy, mass spectrometry, and NMR spectroscopy, we show that uridine diphosphate glucose (UDP-glucose) is a substrate of a fungal Viperin (58% pairwise identity with human Viperin at the amino acid level) in vitro.	Uridine Diphosphate Glucose	118-145	radical S-adenosyl methionine domain containing 2	Homo sapiens	229-236
28752893-3	2017	Here, using electron paramagnetic resonance (EPR) spectroscopy, mass spectrometry, and NMR spectroscopy, we show that uridine diphosphate glucose (UDP-glucose) is a substrate of a fungal Viperin (58% pairwise identity with human Viperin at the amino acid level) in vitro.	Uridine Diphosphate Glucose	147-158	radical S-adenosyl methionine domain containing 2	Homo sapiens	187-194
28752893-3	2017	Here, using electron paramagnetic resonance (EPR) spectroscopy, mass spectrometry, and NMR spectroscopy, we show that uridine diphosphate glucose (UDP-glucose) is a substrate of a fungal Viperin (58% pairwise identity with human Viperin at the amino acid level) in vitro.	Uridine Diphosphate Glucose	147-158	radical S-adenosyl methionine domain containing 2	Homo sapiens	229-236
28487256-12	2017	Furthermore, the stimulation of platelets with selective P2Y14 agonists (UDP-glucose, MRS2690) resulted in significant platelet-dependent neutrophil chemotaxis.	Uridine Diphosphate Glucose	73-84	purinergic receptor P2Y, G-protein coupled, 14	Mus musculus	57-62
28743811-4	2017	The overall structures of Tps1 from Candida albicans and Aspergillus fumigatus are essentially identical and reveal N- and C-terminal Rossmann fold domains that form the glucose-6-phosphate and UDP-glucose substrate binding sites, respectively.	Uridine Diphosphate Glucose	194-205	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	26-30
28429856-0	2017	Glycosyltransferase cascades for natural product glycosylation: Use of plant instead of bacterial sucrose synthases improves the UDP-glucose recycling from sucrose and UDP.	Uridine Diphosphate Glucose	129-140	glycosyltransferase	Glycine max	0-19
28429856-2	2017	Sucrose synthase (SuSy) converts sucrose and uridine 5"-diphosphate (UDP) into UDP-glucose.	Uridine Diphosphate Glucose	79-90	sucrose synthase	Glycine max	0-16
28429856-2	2017	Sucrose synthase (SuSy) converts sucrose and uridine 5"-diphosphate (UDP) into UDP-glucose.	Uridine Diphosphate Glucose	79-90	sucrose synthase	Glycine max	18-22
28429856-3	2017	Coupling of SuSy and GT reactions in one-pot cascade transformations creates a UDP cycle, which regenerates the UDP-glucose continuously and so makes it an expedient donor for glucoside production.	Uridine Diphosphate Glucose	112-123	sucrose synthase	Glycine max	12-16
28429856-7	2017	The L637M-T640V double mutant of this SuSy with a 60-fold reduced KM for UDP substantially improved UDP-glucose recycling.	Uridine Diphosphate Glucose	100-111	sucrose synthase	Glycine max	38-42
28429856-10	2017	The herein gained in-depth understanding of requirements for UDP-glucose regeneration supports development of efficient GT-SuSy cascades.	Uridine Diphosphate Glucose	61-72	sucrose synthase	Glycine max	123-127
28490633-1	2017	The enzyme UDP-glucose:glycoprotein glucosyltransferase (UGGT) mediates quality control of glycoproteins in the endoplasmic reticulum by attaching glucose to N-linked glycan of misfolded proteins.	Uridine Diphosphate Glucose	11-22	UDP-glucose-glycoprotein glucosyltransferase	Drosophila melanogaster	57-61
28425481-3	2017	In the model organism Arabidopsis thaliana, SA glucose conjugates are formed by two homologous enzymes (UGT74F1 and UGT74F2) that transfer glucose from UDP-glucose to SA.	Uridine Diphosphate Glucose	152-163	UDP-glycosyltransferase 74 F1	Arabidopsis thaliana	104-111
27935279-3	2017	Here, we find that OGT uses UDP-glucose to install O-linked glucose (O-Glc) onto proteins only 25-fold less efficiently than O-GlcNAc.	Uridine Diphosphate Glucose	28-39	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	19-22
27880021-5	2017	In addition, NDPK1 levels positively affected UDP-glucose and cellulose contents.	Uridine Diphosphate Glucose	46-57	nucleoside diphosphate kinase	Solanum tuberosum	13-18
28078011-4	2016	In this study, we aimed to investigate the role of URI, an unconventional prefoldin RBP5 interactor, in potassium dichromate induced oxidative stress and cell death through in vitro loss-of-function studies.	Uridine Diphosphate Glucose	51-54	retinol binding protein 5	Homo sapiens	84-88
27587357-6	2017	We conclude that the hut1+ gene product is involved in UDP-Glc entrance into the ER, but that at least another as yet unknown NST displaying an unconventional sequence operates in the yeast secretory pathway.	Uridine Diphosphate Glucose	55-62	UDP-galactose transporter HUT1	Saccharomyces cerevisiae S288C	21-25
27863043-1	2016	The GPR17 receptor is a G protein-coupled receptor (GPCR) that seems to respond to two unrelated families of endogenous ligands: nucleotide sugars (UDP, UDP-galactose, and UDP-glucose) and cysteinyl leukotrienes (LTD4 , LTC4 , and LTE4 ), with significant affinity at micromolar and nanomolar concentrations, respectively.	Uridine Diphosphate Glucose	172-183	G protein-coupled receptor 17	Homo sapiens	4-9
26903444-3	2016	RESULTS: Among AFA components, PCB presented the strongest inhibitory effect on UGDH activity, acting as a competitive inhibitor with respect to UDP-glucose and a non-competitive inhibitor with respect to NAD(+).	Uridine Diphosphate Glucose	145-156	UDP-glucose 6-dehydrogenase	Homo sapiens	80-84