PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 35509570-7 2022 Molecular profiling revealed the presence of a fusion between ZFTA (previously known as C11orf95) and RELA fusion. zfta 62-66 zinc finger translocation associated Homo sapiens 88-96 35348910-7 2022 p65 displayed the highest specificity (93.8%), while L1CAM had the highest sensitivity (92.3%) in detecting ZFTA fusions. zfta 108-112 L1 cell adhesion molecule Homo sapiens 53-58 35509570-8 2022 Conclusion: We report a case of extensive synaptophysin immunoreactivity in a ZFTA-RELA fusion-positive ependymoma that had undergone malignant transformation from a clear cell ependymoma and has long-term follow-up, contributing to the assessment of prognostic significance of synaptophysin immunoreactivity in supratentorial ependymoma, ZFTA fusion positive. zfta 78-82 synaptophysin Homo sapiens 42-55 35509570-8 2022 Conclusion: We report a case of extensive synaptophysin immunoreactivity in a ZFTA-RELA fusion-positive ependymoma that had undergone malignant transformation from a clear cell ependymoma and has long-term follow-up, contributing to the assessment of prognostic significance of synaptophysin immunoreactivity in supratentorial ependymoma, ZFTA fusion positive. zfta 78-82 RELA proto-oncogene, NF-kB subunit Homo sapiens 83-87 35509570-8 2022 Conclusion: We report a case of extensive synaptophysin immunoreactivity in a ZFTA-RELA fusion-positive ependymoma that had undergone malignant transformation from a clear cell ependymoma and has long-term follow-up, contributing to the assessment of prognostic significance of synaptophysin immunoreactivity in supratentorial ependymoma, ZFTA fusion positive. zfta 339-343 synaptophysin Homo sapiens 42-55 33879448-1 2021 Molecular groups of supratentorial ependymomas comprise tumors with ZFTA-RELA or YAP1-involving fusions and fusion-negative subependymoma. zfta 68-72 RELA proto-oncogene, NF-kB subunit Homo sapiens 73-77 35087169-4 2022 Interestingly, the transcription factors promoting ciliogenesis (ciliary TFs) (e.g., multicilin) and ZFTA-RELA upregulated luciferase activity using a 5" upstream sequence of ZFTA in cultured cells. zfta 175-179 multiciliate differentiation and DNA synthesis associated cell cycle protein Mus musculus 85-95 35087169-4 2022 Interestingly, the transcription factors promoting ciliogenesis (ciliary TFs) (e.g., multicilin) and ZFTA-RELA upregulated luciferase activity using a 5" upstream sequence of ZFTA in cultured cells. zfta 175-179 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 101-110 33879448-4 2021 Somatic overexpression of ZFTA-associated fusion genes in the developing cerebral cortex is capable of inducing tumor formation in vivo, and cross-species comparative analyses identified GLI2 as a key downstream regulator of tumorigenesis in all tumors. zfta 26-30 GLI family zinc finger 2 Homo sapiens 187-191 33879448-5 2021 Targeting GLI2 with arsenic trioxide caused extended survival of tumor-bearing animals, indicating a potential therapeutic vulnerability in ZFTA fusion-positive tumors. zfta 140-144 GLI family zinc finger 2 Homo sapiens 10-14