PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30255775-5	2018	Comb-p, DMRcate, and GlobalP detected very similar DMRs near the gene CPT1A on chromosome 11 in both the pre- and posttreatment data.	dmrs	51-55	carnitine palmitoyltransferase 1A	Homo sapiens	70-75
30870065-10	2019	Gene Set Enrichment Analysis of CL/P-associated DMRs showed an over-representation of genes involved in palate development such as WNT9B, MIR140 and LHX8.	dmrs	48-52	Wnt family member 9B	Homo sapiens	131-136
30870065-10	2019	Gene Set Enrichment Analysis of CL/P-associated DMRs showed an over-representation of genes involved in palate development such as WNT9B, MIR140 and LHX8.	dmrs	48-52	microRNA 140	Homo sapiens	138-144
30870065-10	2019	Gene Set Enrichment Analysis of CL/P-associated DMRs showed an over-representation of genes involved in palate development such as WNT9B, MIR140 and LHX8.	dmrs	48-52	LIM homeobox 8	Homo sapiens	149-153
29059699-11	2018	Conversely, FBLIM1 and CYR61, encoding proteins that reduce cell proliferation, showed hypomethylated DMRs and were upregulated.	dmrs	102-106	filamin binding LIM protein 1	Homo sapiens	12-18
29059699-11	2018	Conversely, FBLIM1 and CYR61, encoding proteins that reduce cell proliferation, showed hypomethylated DMRs and were upregulated.	dmrs	102-106	cellular communication network factor 1	Homo sapiens	23-28
25491312-4	2015	The vast majority (~80%) of DMRs were hypermethylated between P1 and P14, and these hypermethylated regions were associated with transcriptional shut down of important developmental signaling pathways, including Hedgehog, bone morphogenetic protein, TGF-beta, fibroblast growth factor, and Wnt/beta-catenin signaling.	dmrs	28-32	zinc finger protein 185	Mus musculus	62-72
27369467-0	2016	Evaluation of DNA methylation at imprinted DMRs in the spermatozoa of oligozoospermic men in association with MTHFR C677T genotype.	dmrs	43-47	methylenetetrahydrofolate reductase	Homo sapiens	110-115
26544189-7	2015	The methylation defects observed in five RHM biopsies from NLRP7 defective patients are restricted to lack-of-methylation at maternal DMRs.	dmrs	134-138	NLR family pyrin domain containing 7	Homo sapiens	59-64
25960295-5	2015	Similarly, Adam2, Uggt2, and Scp2 were hypomethylated in female embryonic germ (EG) cells and not in male EG cells, indicating that these S-DMRs are liver-specific male hypo-S-DMRs.	dmrs	140-144	a disintegrin and metallopeptidase domain 2	Mus musculus	11-16
25960295-5	2015	Similarly, Adam2, Uggt2, and Scp2 were hypomethylated in female embryonic germ (EG) cells and not in male EG cells, indicating that these S-DMRs are liver-specific male hypo-S-DMRs.	dmrs	140-144	sterol carrier protein 2, liver	Mus musculus	29-33
25491312-4	2015	The vast majority (~80%) of DMRs were hypermethylated between P1 and P14, and these hypermethylated regions were associated with transcriptional shut down of important developmental signaling pathways, including Hedgehog, bone morphogenetic protein, TGF-beta, fibroblast growth factor, and Wnt/beta-catenin signaling.	dmrs	28-32	transforming growth factor, beta 1	Mus musculus	250-258
25491312-4	2015	The vast majority (~80%) of DMRs were hypermethylated between P1 and P14, and these hypermethylated regions were associated with transcriptional shut down of important developmental signaling pathways, including Hedgehog, bone morphogenetic protein, TGF-beta, fibroblast growth factor, and Wnt/beta-catenin signaling.	dmrs	28-32	catenin (cadherin associated protein), beta 1	Mus musculus	294-306
24810686-9	2014	Maternally methylated DMRs were susceptible to aberrant hypomethylation in KvDMR1-loss of methylation patients.	dmrs	22-26	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	75-81
24158121-6	2015	RESULTS: After adjusting for potential confounders and cluster effects, paternal obesity was significantly associated with lower methylation levels at the MEST (beta=-2.57; s.e.=0.95; P=0.008), PEG3 (beta=-1.71; s.e.=0.61; P=0.005) and NNAT (beta=-3.59; s.e.=1.76; P=0.04) DMRs.	dmrs	273-277	mesoderm specific transcript	Homo sapiens	155-159
23335487-6	2013	A mutation analysis identified a 1 bp deletion in the ZFP57 gene in a TNDM patient with methylation defects at multiple maternal DMRs.	dmrs	129-133	ZFP57 zinc finger protein	Homo sapiens	54-59
24291790-8	2013	Genome-wide DNA methylation analysis of embryonic day 13.5 PGCs and sperm of Tet1 knockout mice revealed hypermethylation of DMRs of imprinted genes in sperm, which can be traced back to PGCs.	dmrs	125-129	tet methylcytosine dioxygenase 1	Mus musculus	77-81
23844573-0	2013	Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies.	dmrs	36-40	GNAS complex locus	Homo sapiens	31-35
23549870-6	2013	Furthermore, the number of DMRs associated with Gleason score was greatly expanded by stratifying samples into ERG-positive versus ERG-negative, with ERG-positive/GS-associated DMRs being primarily hypermethylated as opposed to hypomethylated.	dmrs	27-31	ETS transcription factor ERG	Homo sapiens	111-114
23549870-6	2013	Furthermore, the number of DMRs associated with Gleason score was greatly expanded by stratifying samples into ERG-positive versus ERG-negative, with ERG-positive/GS-associated DMRs being primarily hypermethylated as opposed to hypomethylated.	dmrs	27-31	ETS transcription factor ERG	Homo sapiens	131-134
23549870-6	2013	Furthermore, the number of DMRs associated with Gleason score was greatly expanded by stratifying samples into ERG-positive versus ERG-negative, with ERG-positive/GS-associated DMRs being primarily hypermethylated as opposed to hypomethylated.	dmrs	27-31	ETS transcription factor ERG	Homo sapiens	131-134
22425776-5	2012	Interestingly, treatment of cells with a methyl transferase inhibitor (5-aza-2-deoxycytidine, DAC) significantly increased expression of miRNA genes with a high frequency of the C[N](6)CT motif in DMRs.	dmrs	197-201	arylacetamide deacetylase	Homo sapiens	94-97
22394678-5	2012	However, the allele-specific DNA methylation patterns of the DMRs of Peg3, Zim2 and Zim3 were not affected in the mice that inherited the KO allele either paternally or maternally.	dmrs	61-65	paternally expressed 3	Mus musculus	69-73
23132697-10	2013	Broad methylation abnormalities were observed in the GNAS DMRs.	dmrs	58-62	GNAS complex locus	Homo sapiens	53-57
21281512-4	2011	These DMRs, in addition to being either maternally or paternally methylated, have differences in whether methylation was acquired in the germ-line or post fertilization and are present in a variety of genomic locations with different Cytosine-phosphate guanine (CpG) densities and CTCF binding capacities.	dmrs	6-10	CCCTC-binding factor	Homo sapiens	281-285
18922938-10	2008	One example of a newly discovered agglomerate of hypermethylated DMRs associated with gene silencing in breast cancer that we examined in greater detail involved the protocadherin gene family clusters on chromosome 5 (PCDHA, PCDHB, and PCDHG).	dmrs	65-69	protocadherin alpha cluster, complex locus	Homo sapiens	218-223
20807523-4	2010	METHODS: This study describes the first quantitative methylation analysis of multiple CpG sites for three different GNAS DMRs using the Sequenom EpiTYPER in 35 controls, 12 PHPIb patients, 2 PHPIa patients and 2 patients without parathormone (PTH) resistance but having only hypocalcemia and hyperphosphatemia.	dmrs	121-125	GNAS complex locus	Homo sapiens	116-120
19628663-7	2009	Overall, the current study suggests that YY1 likely plays a role in the de novo DNA methylation of the DMRs of Peg3 and Xist during oogenesis and also in the maintenance of unmethylation status of these DMRs during spermatogenesis.	dmrs	103-107	YY1 transcription factor	Mus musculus	41-44
19628663-7	2009	Overall, the current study suggests that YY1 likely plays a role in the de novo DNA methylation of the DMRs of Peg3 and Xist during oogenesis and also in the maintenance of unmethylation status of these DMRs during spermatogenesis.	dmrs	103-107	paternally expressed 3	Mus musculus	111-115
19628663-7	2009	Overall, the current study suggests that YY1 likely plays a role in the de novo DNA methylation of the DMRs of Peg3 and Xist during oogenesis and also in the maintenance of unmethylation status of these DMRs during spermatogenesis.	dmrs	103-107	inactive X specific transcripts	Mus musculus	120-124
18922938-10	2008	One example of a newly discovered agglomerate of hypermethylated DMRs associated with gene silencing in breast cancer that we examined in greater detail involved the protocadherin gene family clusters on chromosome 5 (PCDHA, PCDHB, and PCDHG).	dmrs	65-69	protocadherin beta cluster	Homo sapiens	225-230
18922938-10	2008	One example of a newly discovered agglomerate of hypermethylated DMRs associated with gene silencing in breast cancer that we examined in greater detail involved the protocadherin gene family clusters on chromosome 5 (PCDHA, PCDHB, and PCDHG).	dmrs	65-69	protocadherin gamma cluster	Homo sapiens	236-241
12975326-4	2003	We show that, in both DMRs, the active alleles of both Igf2r, and Air are associated with acetylated histones (H3, and H4), acetyl lysine 9 of histone H3 (H3 K9-Ac), and methyl lysine 4 of histone H3 (H3 K4-Me).	dmrs	22-26	insulin-like growth factor 2 receptor	Mus musculus	55-60
17126526-5	2007	Chromatin immunoprecipitation was therefore used to examine the pattern of histone modifications across the IG and Gtl2 DMRs.	dmrs	120-124	maternally expressed 3	Mus musculus	115-119
33422657-9	2021	GO and KEGG analysis showed DEGs, DAPs, and DMRs enriched in the cancer-related biological processes of calcium signaling pathway, pathways in cancer, metabolic pathways, MAPK signaling pathway, PI3K-Akt signaling pathway, and transcriptional misregulation in cancer.	dmrs	44-48	AKT serine/threonine kinase 1	Homo sapiens	200-203
34280322-8	2021	DMPs and DMRs encompassed genes involved in lipid (LPCAT1) and glucose (PFKFB3) metabolism and importantly, DNAm status was associated with disease severity in IPF.	dmrs	9-13	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Homo sapiens	72-78
35508123-2	2022	In this study, we show that cocaine exposure worsens the learning and memory of doxycycline-inducible and brain-specific HIV Tat transgenic mice (iTat) and results in 14,838 hypermethylated CpG-related differentially methylated regions (DMRs) and 15,800 hypomethylated CpG-related DMRs, which are linked to 52 down- and 127 upregulated genes, respectively, in the hippocampus of iTat mice.	dmrs	281-285	tyrosine aminotransferase	Mus musculus	125-128
34280322-8	2021	DMPs and DMRs encompassed genes involved in lipid (LPCAT1) and glucose (PFKFB3) metabolism and importantly, DNAm status was associated with disease severity in IPF.	dmrs	9-13	lysophosphatidylcholine acyltransferase 1	Homo sapiens	51-57
35629083-4	2022	We found that age was a significant predictor in obese cancer patients, both alone (p = 0.003) and interacting with hypomethylated DMRs of ZBTB46, a tumor suppressor gene (p = 0.008).	dmrs	131-135	zinc finger and BTB domain containing 46	Homo sapiens	139-145
31484384-13	2019	Using chromatin contact data, we saw that conserved DMRs were topologically associated with metabolism genes, which were associated with differential expression of Adh5, Enox1, and Pik3c3.	dmrs	52-56	alcohol dehydrogenase 5 (class III), chi polypeptide	Rattus norvegicus	164-168
31621494-6	2020	DNA methylation analyses conducted in conjunction with reported symptoms of tinnitus in the low versus high blast incidents groups identified DMRS in KCNE1 and CYP2E1 genes.	dmrs	142-146	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	150-155
31621494-6	2020	DNA methylation analyses conducted in conjunction with reported symptoms of tinnitus in the low versus high blast incidents groups identified DMRS in KCNE1 and CYP2E1 genes.	dmrs	142-146	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	160-166
30822522-5	2020	We observed DDT DMRs in three genes, CCDC85A, CYP1A1 and ZFPM2, each of which has been previously implicated in pubertal development and breast cancer susceptibility.	dmrs	16-20	coiled-coil domain containing 85A	Homo sapiens	37-44
30822522-5	2020	We observed DDT DMRs in three genes, CCDC85A, CYP1A1 and ZFPM2, each of which has been previously implicated in pubertal development and breast cancer susceptibility.	dmrs	16-20	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	46-52
30822522-5	2020	We observed DDT DMRs in three genes, CCDC85A, CYP1A1 and ZFPM2, each of which has been previously implicated in pubertal development and breast cancer susceptibility.	dmrs	16-20	zinc finger protein, FOG family member 2	Homo sapiens	57-62
31003786-8	2019	DMRs included six nonoverlapping DMRs (three in the Netherlands Twin Register, three in the Dunedin study) in the major histocompatibility complex, which were associated with expression of genes in the major histocompatibility complex, including C4A and C4B, previously implicated in schizophrenia.	dmrs	0-4	complement C4A (Rodgers blood group)	Homo sapiens	246-249
31003786-8	2019	DMRs included six nonoverlapping DMRs (three in the Netherlands Twin Register, three in the Dunedin study) in the major histocompatibility complex, which were associated with expression of genes in the major histocompatibility complex, including C4A and C4B, previously implicated in schizophrenia.	dmrs	0-4	complement C4B (Chido blood group)	Homo sapiens	254-257
31003786-8	2019	DMRs included six nonoverlapping DMRs (three in the Netherlands Twin Register, three in the Dunedin study) in the major histocompatibility complex, which were associated with expression of genes in the major histocompatibility complex, including C4A and C4B, previously implicated in schizophrenia.	dmrs	33-37	complement C4A (Rodgers blood group)	Homo sapiens	246-249
31484384-13	2019	Using chromatin contact data, we saw that conserved DMRs were topologically associated with metabolism genes, which were associated with differential expression of Adh5, Enox1, and Pik3c3.	dmrs	52-56	ecto-NOX disulfide-thiol exchanger 1	Rattus norvegicus	170-175
31484384-13	2019	Using chromatin contact data, we saw that conserved DMRs were topologically associated with metabolism genes, which were associated with differential expression of Adh5, Enox1, and Pik3c3.	dmrs	52-56	phosphatidylinositol 3-kinase, catalytic subunit type 3	Rattus norvegicus	181-187