PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33963183-10 2021 Overall, here we report distinct fates of EVPs according to the relative expression of Rbpj or Notch signalling and Sox9, highlighting their potential plasticity and opening exciting avenues for more effective therapies in fibrotic diseases. evps 42-46 recombination signal binding protein for immunoglobulin kappa J region Homo sapiens 87-91 35088795-5 2022 Here, we developed a novel therapeutic strategy for local delivery and treatment using EVPs, which are derived from NSCs with the expression of the CNS lesion targeting ligand-PDGFRalpha. evps 87-91 platelet derived growth factor receptor, alpha polypeptide Mus musculus 176-186 33963183-10 2021 Overall, here we report distinct fates of EVPs according to the relative expression of Rbpj or Notch signalling and Sox9, highlighting their potential plasticity and opening exciting avenues for more effective therapies in fibrotic diseases. evps 42-46 SRY-box transcription factor 9 Homo sapiens 116-120 33148515-3 2020 Taken that BDNF and anti-inflammatory effects have been related to functional outcomes, and BDNF and IL-1beta have been detected in circulating EVPs, our aim was to evaluate circulating total EVPs profile from adult and aged Wistar rats submitted to exercise modalities, namely aerobic, acrobatic, resistance or combined for 20 min, 3 times a week, during 12 weeks. evps 144-148 brain-derived neurotrophic factor Rattus norvegicus 92-96 33148515-3 2020 Taken that BDNF and anti-inflammatory effects have been related to functional outcomes, and BDNF and IL-1beta have been detected in circulating EVPs, our aim was to evaluate circulating total EVPs profile from adult and aged Wistar rats submitted to exercise modalities, namely aerobic, acrobatic, resistance or combined for 20 min, 3 times a week, during 12 weeks. evps 144-148 interleukin 1 alpha Rattus norvegicus 101-109 33148515-6 2020 Changes on EVPs profile, such as increased CD63 levels can be related, at least in part, to an exercise-induced healthier global status. evps 11-15 Cd63 molecule Rattus norvegicus 43-47 33148515-4 2020 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps 131-135 brain-derived neurotrophic factor Rattus norvegicus 110-114 33148515-4 2020 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps 131-135 interleukin 1 alpha Rattus norvegicus 119-127 33148515-4 2020 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps 131-135 brain-derived neurotrophic factor Rattus norvegicus 110-114 33148515-4 2020 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps 131-135 interleukin 1 alpha Rattus norvegicus 119-127 33148515-5 2020 Besides, all exercise modalities attenuated aging-induced CD63 changes in circulating total EVPs; this finding can be involved with reduced mortality rate and improved memory performance previously observed. evps 92-96 Cd63 molecule Rattus norvegicus 58-62 32467855-8 2020 After controlling for sociodemographics, a strong graded relationship between cumulative ACE exposure and early initiation of EVPs was observed: 1 ACE (AOR = 1.60; 95% CI = 0.99-2.59), 2 ACEs (AOR = 2.29; 95% CI = 1.33-3.93), and 3-6 ACEs (AOR = 3.43, 95% CI = 2.20-5.36) compared to no ACEs. evps 126-130 angiotensin I converting enzyme Homo sapiens 89-92 32467855-8 2020 After controlling for sociodemographics, a strong graded relationship between cumulative ACE exposure and early initiation of EVPs was observed: 1 ACE (AOR = 1.60; 95% CI = 0.99-2.59), 2 ACEs (AOR = 2.29; 95% CI = 1.33-3.93), and 3-6 ACEs (AOR = 3.43, 95% CI = 2.20-5.36) compared to no ACEs. evps 126-130 angiotensin I converting enzyme Homo sapiens 147-150