PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20528774-1	2010	MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate by hydrogen peroxide to HOCl (hypochlorous acid), HOBr (hypobromous acid) and HOSCN (hypothiocyanous acid) respectively.	Bromides	59-66	myeloperoxidase	Mus musculus	0-3
21320803-3	2011	One more methene group in the side chain of Q64 of hCA VII makes it possible to form the hydrogen bond with the bromide atom of the known inhibitor.	Bromides	112-119	carbonic anhydrase 7	Homo sapiens	51-58
21516990-7	2011	Br-THM (brominated THM species) were much higher than Br-HAA (brominated HAA species), and the formation of Br-DBP (Br-THM and Br-HAA) should be of concern when the bromide concentration is over 100 microg/L.	Bromides	165-172	D-box binding PAR bZIP transcription factor	Homo sapiens	111-114
21555141-11	2011	Bromide shifted the DBP species into brominated DBPs, and this phenomenon was more apparent when BKC was treated with chloramine.	Bromides	0-7	D-box binding PAR bZIP transcription factor	Homo sapiens	20-23
20528774-1	2010	MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate by hydrogen peroxide to HOCl (hypochlorous acid), HOBr (hypobromous acid) and HOSCN (hypothiocyanous acid) respectively.	Bromides	59-66	myeloperoxidase	Mus musculus	5-20
20023875-8	2009	The unusual observation that the chloride complexes show stronger magnetic exchange than the bromide complexes provides strong support that the exchange can be strongly dependent upon the Cu-X...X angles and Cu-X...X-Cu torsion angles.	Bromides	93-100	cut like homeobox 1	Homo sapiens	188-192
20583061-1	2010	FeCl(3)6 H(2)O- and FeBr(3)-catalyzed Prins cyclization/halogenation of alkynyl aldehyde acetals has been realized with acetyl chloride or bromide as halogen source in dichloromethane to afford 2-(1-halobenzylidene or alkylidene)-substituted five-membered carbo- and heterocycles, and thus provides an alternative route for vinylic C-Cl and C-Br bond formation.	Bromides	139-146	carbonyl reductase 1	Homo sapiens	341-345
20023875-8	2009	The unusual observation that the chloride complexes show stronger magnetic exchange than the bromide complexes provides strong support that the exchange can be strongly dependent upon the Cu-X...X angles and Cu-X...X-Cu torsion angles.	Bromides	93-100	cut like homeobox 1	Homo sapiens	208-212
18324782-5	2008	The salt concentration and type dependencies of the mutants relative to wild-type IRF1 DBD provide evidence of charge neutralization by solution ions for R64 and by a salt bridge between D73 and K75 in buffer containing chloride or bromide salts.	Bromides	232-239	interferon regulatory factor 1	Homo sapiens	82-86
18657284-1	2008	This work investigated the effect of several metal oxides including alpha-FeOOH, alpha-Fe(2)O(3), gamma-FeOOH, and CeO(2) on bromate formation potential (BFP) during ozonation of bromide-containing water.	Bromides	179-186	ring finger protein 112	Homo sapiens	154-157
18688343-1	2008	Benzylic zinc reagents prepared by direct insertion of zinc to benzylic chlorides in the presence of LiCl undergo smooth cross-coupling reactions with aromatic chlorides, bromides and tosylates using Ni(acac)(2) and PPh(3) as a catalyst system.	Bromides	171-179	caveolin 1	Homo sapiens	216-222
18235995-1	2008	Various non-natural C(3)- and C(4)-symmetric alpha-amino acid derivatives have been synthesized via Suzuki-Miyaura cross-coupling reaction between aromatic iodides or bromide and a suitably protected DL-4-boronophenylalanine derivative.	Bromides	167-174	complement C3	Homo sapiens	20-50
18327942-1	2008	The zirconium imido complex Cp2(THF)Zr=NSi(t-Bu)Me2 (1) reacts with allylic ethers, chlorides, and bromides to give exclusively the products of the SN2" reaction; i.e., attack at the allylic position remote from the leaving group with migration of the double bond.	Bromides	99-107	ceruloplasmin	Homo sapiens	28-31
18851713-1	2009	MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate to their respective hypohalous acids.	Bromides	59-66	myeloperoxidase	Homo sapiens	0-3
18851713-1	2009	MPO (myeloperoxidase) catalyses the oxidation of chloride, bromide and thiocyanate to their respective hypohalous acids.	Bromides	59-66	myeloperoxidase	Homo sapiens	5-20
19267305-13	2009	Important factors for determining sufficient similarity of DBP mixtures found in this research include disinfectant used; source water characteristics, including the concentrations of bromide and total organic carbon; concentrations and proportions of individual DBPs with known toxicity data on the same endpoint; magnitude of the unidentified fraction of total organic halides; similar toxicity outcomes for whole mixture testing (e.g., mutagenicity); and summary chemical measures such as total trihalomethanes, total haloacetic acids, total haloacetonitriles, and the levels of bromide incorporation in the DBP classes.	Bromides	582-589	D-box binding PAR bZIP transcription factor	Homo sapiens	59-62
18805568-5	2008	In tap water, at the groundwater supplied sampling point, brominated species, bromoform and dibromoacetonitrile, were detected at the highest levels most probably due to bromide ion intrusion from seawater.	Bromides	170-177	nuclear RNA export factor 1	Homo sapiens	3-6
18604829-3	2008	In particular, the cross-coupling reactions of the benzylic zinc chlorides with aromatic chlorides, bromides, and tosylates in the presence of [Ni(acac)(2)] (acac=acetylacetonate) and PPh(3) proceeded in good to excellent yields to give the corresponding diaryl and heterodiaryl methanes.	Bromides	100-108	caveolin 1	Homo sapiens	184-190
18516076-5	2008	KEY RESULTS: In the presence of plasma levels of bromide (Br-), melatonin inactivates EPO at two different points in the classic peroxidase cycle.	Bromides	49-56	eosinophil peroxidase	Homo sapiens	86-89
21202733-2	2008	The Co(II) center is six-coordinated by four N atoms from one bis-[4-(2-pyrid-yl)pyrimidin-2-yl] sulfide (L) ligand and two bromide anions, forming an octa-hedral coordination geometry, where the four donor N atoms are located in the equatorial plane and the Br atoms occupy the axial positions.	Bromides	124-131	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
18036632-5	2008	When irradiating P25 suspensions containing bromide and 2,4-dihydroxybenzoic acid (DHBA, high bromoform formation potential), we observed the formation of significant amounts of bromoform (up to 10microgL(-1)).	Bromides	44-51	tubulin polymerization promoting protein	Homo sapiens	17-20
18183990-2	2008	The modules, i.e., monoprotected o-, m-, and p-benzenediboronic acid derivatives, undergo highly selective Suzuki-Miyaura coupling with sp2 iodides, bromides, chlorides, and triflates, affording coupling products in which the protected boronyl groups are left intact.	Bromides	149-157	Sp2 transcription factor	Homo sapiens	136-139
17604010-1	2007	The leukocyte enzyme myeloperoxidase (MPO) is capable of catalyzing the oxidation of chloride and bromide ions, at physiological concentrations of these substrates, by hydrogen peroxide, generating hypochlorous acid (HOCl) and hypobromous acid (HOBr), respectively.	Bromides	98-105	myeloperoxidase	Homo sapiens	21-36
18094145-4	2008	ORP150 expression was found to be regulated by the anti-C/enhancer-binding protein homologous protein (CHOP)/GADD153 transcription factor and ORP150 levels increased in the mitochondria and ER of COS-7 cells after diverse stresses, including hypoxia, serum starvation, prolyl hydroxylase inhibition with dimethyloxaloylglycine, and exposure to tunicamycin, ethidium, bromide, and 2-deoxyglucose.	Bromides	367-374	hypoxia up-regulated 1	Rattus norvegicus	0-6
18094145-4	2008	ORP150 expression was found to be regulated by the anti-C/enhancer-binding protein homologous protein (CHOP)/GADD153 transcription factor and ORP150 levels increased in the mitochondria and ER of COS-7 cells after diverse stresses, including hypoxia, serum starvation, prolyl hydroxylase inhibition with dimethyloxaloylglycine, and exposure to tunicamycin, ethidium, bromide, and 2-deoxyglucose.	Bromides	367-374	DNA-damage inducible transcript 3	Rattus norvegicus	103-107
18094145-4	2008	ORP150 expression was found to be regulated by the anti-C/enhancer-binding protein homologous protein (CHOP)/GADD153 transcription factor and ORP150 levels increased in the mitochondria and ER of COS-7 cells after diverse stresses, including hypoxia, serum starvation, prolyl hydroxylase inhibition with dimethyloxaloylglycine, and exposure to tunicamycin, ethidium, bromide, and 2-deoxyglucose.	Bromides	367-374	DNA-damage inducible transcript 3	Rattus norvegicus	109-116
18217604-1	2007	Enynes bearing an iodide (bromide) at their alkyne terminus react with catalytic amounts of [Cp*Ru(MeCN)3]PF6 in DMF to give strained iodo(bromo)cyclobutene derivatives in good to excellent yields.	Bromides	26-33	sperm associated antigen 17	Homo sapiens	106-109
17761422-5	2007	The best hCA VB inhibitors were cyanate, thiocyanate, cyanide and hydrogensulfide (K(I)s of 80-76 microM) whereas the least effective ones were the halides (K(I)s of 11-72 mM), with the best inhibitor being fluoride and the least effective ones bromide and iodide.	Bromides	245-252	carbonic anhydrase 5B	Homo sapiens	9-15
17604010-4	2007	This study was conducted to determine the effect physiological chloride concentration (140 mM) has on the formation of bromohydrins and lyso-PC from unsaturated PC upon treatment with the myeloperoxidase/hydrogen peroxide/bromide (MPO/H2O2/Br-) system using physiological bromide concentrations (20-100 microM).	Bromides	272-279	myeloperoxidase	Homo sapiens	231-234
17604010-8	2007	We attributed these effects to the involvement of HOBr arising from the reaction of MPO-derived HOCl with bromide rather than to the exchange of bromide with chlorine atoms of chlorohydrins or direct formation of HOBr by MPO.	Bromides	106-113	myeloperoxidase	Homo sapiens	84-87
17604010-11	2007	The results indicate that at physiological levels of chloride and bromide, chloride promotes MPO-mediated formation of bromohydrins and lyso-PC in unsaturated phospholipids.	Bromides	66-73	myeloperoxidase	Homo sapiens	93-96
18171054-1	2008	Analytically pure chloride and bromide salts of two different cyclic triphosphenium cations are prepared by the reaction of PX3 (X=Cl, Br) in the presence of the halogen-scavenging reagent cyclohexene.	Bromides	31-44	pannexin 3	Homo sapiens	124-127
17604010-1	2007	The leukocyte enzyme myeloperoxidase (MPO) is capable of catalyzing the oxidation of chloride and bromide ions, at physiological concentrations of these substrates, by hydrogen peroxide, generating hypochlorous acid (HOCl) and hypobromous acid (HOBr), respectively.	Bromides	98-105	myeloperoxidase	Homo sapiens	38-41
17604010-4	2007	This study was conducted to determine the effect physiological chloride concentration (140 mM) has on the formation of bromohydrins and lyso-PC from unsaturated PC upon treatment with the myeloperoxidase/hydrogen peroxide/bromide (MPO/H2O2/Br-) system using physiological bromide concentrations (20-100 microM).	Bromides	222-229	myeloperoxidase	Homo sapiens	231-234
17604010-4	2007	This study was conducted to determine the effect physiological chloride concentration (140 mM) has on the formation of bromohydrins and lyso-PC from unsaturated PC upon treatment with the myeloperoxidase/hydrogen peroxide/bromide (MPO/H2O2/Br-) system using physiological bromide concentrations (20-100 microM).	Bromides	272-279	myeloperoxidase	Homo sapiens	188-203
17241724-4	2007	Adding chloride or bromide salts with Fe(0) (1% w/v) greatly enhanced TNT, RDX, and HMX degradation rates in aqueous solution.	Bromides	19-32	chromosome 16 open reading frame 82	Homo sapiens	70-73
17241724-4	2007	Adding chloride or bromide salts with Fe(0) (1% w/v) greatly enhanced TNT, RDX, and HMX degradation rates in aqueous solution.	Bromides	19-32	radixin	Homo sapiens	75-78
17172764-3	2007	Bromides can, therefore, be used through multiwavelength anomalous diffraction or single-wavelength anomalous diffraction (SAD) techniques and iodides through SAD or multiple isomorphous replacement (MIRAS) phasing.	Bromides	0-8	DNA polymerase gamma, catalytic subunit	Homo sapiens	200-205
17452787-4	2007	Here, two structures of FGE in complex with bromide and iodide were determined in order to further delineate the volume and stereochemical restraints of the oxygen-binding site for potential reaction intermediates.	Bromides	44-51	sulfatase modifying factor 1	Homo sapiens	24-27
17209551-3	2007	The enzyme uses hydrogen peroxide (H2O2) and bromide (Br-), a preferred cosubstrate of EPO, to generate the cytotoxic oxidant hypobromous acid.	Bromides	45-52	eosinophil peroxidase	Homo sapiens	87-90
17359937-8	2007	These findings are discussed with respect to the known crystal structure of MPO and its bromide complex as well as the known redox chemistry of its intermediates and substrates.	Bromides	88-95	myeloperoxidase	Homo sapiens	76-79
17141727-2	2007	Pretreatment of alpha1-antitrypsin with hypohalous acids HOCl and HOBr as well as with the myeloperoxidase-hydrogen peroxide-chloride (or bromide) system inactivated this proteinase.	Bromides	138-145	serpin family A member 1	Homo sapiens	16-34
17141727-2	2007	Pretreatment of alpha1-antitrypsin with hypohalous acids HOCl and HOBr as well as with the myeloperoxidase-hydrogen peroxide-chloride (or bromide) system inactivated this proteinase.	Bromides	138-145	myeloperoxidase	Homo sapiens	91-106
16928126-3	2006	The maximum values of delta increase with increasing separations between the donor/acceptor in the order Cl...Br < Br...Br < I...Br for [NEt4h.CBr4] complexes; however, the TPA cross sections delta vary slightly as the size of the alkyl group increases from methyl to propyl for the bromide as a donor, and the maximum wavelength of the TPA peak lambdamax indicates a bathochromic shift.	Bromides	289-296	carbonyl reductase 4	Homo sapiens	149-153
17723578-11	2006	They were identified as bromo- and bromochloro-parabens, formed due to the existence of traces of bromide in tap water sources.	Bromides	98-105	nuclear RNA export factor 1	Homo sapiens	109-112
21690834-7	2006	With bromide and iodide clearly different behaviour was observed, indicating specific interactions between RR-1 and these counter-ions.	Bromides	5-12	ribonucleotide reductase catalytic subunit M1	Homo sapiens	107-111
16719110-6	2006	At higher levels of bromide, there was a decreasing level of unknown TOX and unknown TOCl but an increasing level of unknown TOBr.	Bromides	20-27	thymocyte selection associated high mobility group box	Homo sapiens	69-72
16288970-4	2006	Based on the published crystal structures of free MPO and its complexes with cyanide, bromide and thiocyanate as well as on sequence analysis and modeling, we critically discuss structure-function relationships.	Bromides	86-93	myeloperoxidase	Homo sapiens	50-53
16706110-2	2006	METHODS: Effect of P3513 (a specific agonist of BRS-3) on the proliferation of HBECs was observed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method; the release rate of 3H-Udr, and LDH activity, catalase activity, and the expression of cadherin and integrin beta1 were also analyzed under O3 stress with or without P3513 treatment.	Bromides	155-162	bombesin receptor subtype 3	Homo sapiens	48-53
16111649-1	2006	The formation of chloro- and bromohydrins from 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine following incubation with myeloperoxidase or eosinophil peroxidase in the presence of hydrogen peroxide, chloride and/or bromide was analysed by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.	Bromides	217-224	eosinophil peroxidase	Homo sapiens	141-162
16125131-0	2006	Bromination and chlorination reactions of myeloperoxidase at physiological concentrations of bromide and chloride.	Bromides	93-100	myeloperoxidase	Homo sapiens	42-57
16443167-4	2006	In the presence of chloride, bromide, and nitrite, the myeloperoxidase-hydrogen peroxide system caused an oxidation, bromination, and nitrosylation/nitration of eight amino acid residues of albumin as detected by fragment analysis of tryptic digests with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.	Bromides	29-36	myeloperoxidase	Homo sapiens	55-70
16125131-4	2006	We have investigated the ability of myeloperoxidase to produce hypobromous acid in the presence of physiological concentrations of chloride and bromide.	Bromides	144-151	myeloperoxidase	Homo sapiens	36-51
16125131-8	2006	Bromide, at physiological concentrations, promoted a dramatic increase in bromination of human serum albumin catalyzed by myeloperoxidase.	Bromides	0-7	myeloperoxidase	Homo sapiens	122-137
16125131-15	2006	We conclude that at physiological concentrations of chloride and bromide, hypobromous acid can be a major oxidant produced by myeloperoxidase.	Bromides	65-72	myeloperoxidase	Homo sapiens	126-141
16297853-1	2006	Three unusual substrates-bromide (Br(-)), nitrite (NO(2)(-)), and thiocyanate (SCN(-))-compete for oxidation by eosinophil peroxidase (EPO) in physiologic fluids in the presence of H(2)O(2) to yield, respectively, hypobromous acid (HOBr), nitrogen dioxide (NO(2)()), or hypothiocyanous acid (HOSCN).	Bromides	25-32	eosinophil peroxidase	Mus musculus	112-133
16297853-1	2006	Three unusual substrates-bromide (Br(-)), nitrite (NO(2)(-)), and thiocyanate (SCN(-))-compete for oxidation by eosinophil peroxidase (EPO) in physiologic fluids in the presence of H(2)O(2) to yield, respectively, hypobromous acid (HOBr), nitrogen dioxide (NO(2)()), or hypothiocyanous acid (HOSCN).	Bromides	25-32	eosinophil peroxidase	Mus musculus	135-138
13680053-6	2003	The method was applied to the determination of bromide ion in seawater samples collected from the Bosphorus and the Black Sea.	Bromides	47-54	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	122-125
16475324-5	2005	A key finding of this research is that the oxidation rate of DMS induced by NO3- photolysis is dramatically enhanced in the presence of bromide ion.	Bromides	136-143	NBL1, DAN family BMP antagonist	Homo sapiens	76-79
16235921-2	2005	The reactions of 1 with phenyl iodide or bromide under Pd(PPh(3))(4)/CsF/Ag(2)O or Pd(2)(dba)(3)/P(t-Bu)(3)/CsF/Ag(2)O catalytic system conditions gave 2,3,4,5,6-pentafluoro-1,1"-biphenyl (3a) in more than 90% yields.	Bromides	41-48	colony stimulating factor 2	Homo sapiens	69-72
15911318-4	2005	Structure-activity analysis indicates that replacements of chlorides of EA by methyl, bromide, and fluoride at 3" position remain the GSTP1-1 inhibitory effect.	Bromides	86-93	glutathione S-transferase pi 1	Homo sapiens	134-141
15876088-1	2005	[reaction: see text] A variety of 1,5-diaryl-1H-imidazoles have been regioselectively synthesized by direct coupling of 1-aryl-1H-imidazoles with aryl iodides or bromides in DMF in the presence of CsF as the base and a catalyst precursor consisting of a mixture of Pd(OAc)2 and AsPh3.	Bromides	162-170	colony stimulating factor 2	Homo sapiens	197-200
15605154-1	2005	Reactions of the halides X- (X- = chloride, bromide or iodide) with the substituted cluster Rh6(CO)15(PPh3) in oxygen-free chloroform lead to [Rh5(CO)14(PPh3)]-, Rh(CO)2(PPh3)2X and [Rh(CO)2X2]- in the molar ratios 2:1: approximately 13.	Bromides	44-51	protein phosphatase 4 catalytic subunit	Homo sapiens	102-106
16166591-1	2006	In vivo, bromide (Br(-)), nitrite (NO(2)(-)), and thiocyanate (SCN(-)) compete for oxidation by eosinophil peroxidase (EPO) and H(2)O(2), yielding, respectively, HOBr, NO(2)., and HOSCN.	Bromides	9-16	eosinophil peroxidase	Homo sapiens	96-117
16166591-1	2006	In vivo, bromide (Br(-)), nitrite (NO(2)(-)), and thiocyanate (SCN(-)) compete for oxidation by eosinophil peroxidase (EPO) and H(2)O(2), yielding, respectively, HOBr, NO(2)., and HOSCN.	Bromides	9-16	eosinophil peroxidase	Homo sapiens	119-122
16144367-1	2005	A bromide salt of a TTF-based cross-cyclophane-type donor displayed characteristic nonlinear voltage-biased conductivity.	Bromides	2-14	ras homolog family member H	Homo sapiens	20-23
15128240-1	2004	We demonstrate that sterically bulky N,N"-disubstituted cyclic thiourea-Pd(0) complexes are air- and moisture-stable and highly active catalysts for palladium-catalyzed Heck reaction of aryl iodides and bromides with olefins (TONs up to 500000 for the reaction of PhI and methyl acrylate).	Bromides	203-211	glucose-6-phosphate isomerase	Homo sapiens	264-267
15115411-1	2004	The synthesis of a series of C-10 trifluoromethyl ethers of artemisinin has been achieved from key bromide 8, itself carried out in two steps from artemisinin.	Bromides	99-106	gene rich cluster, C10 gene	Mus musculus	29-33
12943506-1	2003	It was established that nitrite in the presence of chloride, bromide, and thiocyanate decreases the rate of hydrogen peroxide decomposition by catalase.	Bromides	61-68	catalase	Homo sapiens	143-151
14531697-1	2003	A single method (2% Pd(2)(dba)(3)/8% PCyp(3)/NMI in THF/NMP at 80 degrees C; Cyp = cyclopentyl) achieves the cross-coupling of a range of beta-hydrogen-containing primary alkyl iodides, bromides, chlorides, and tosylates with an array of alkyl-, alkenyl-, and arylzinc halides.	Bromides	186-194	peptidylprolyl isomerase G	Homo sapiens	38-41
12948197-9	2003	Bromide 16 participates in palladium catalysed Stille and Suzuki cross-couplings allowing access to C-2 substituted imino sugars 17 and 18.	Bromides	0-7	complement C2	Homo sapiens	100-103
13129364-4	2003	For the tetraethylammonium bromide/carbon tetrabromide dyad, the three-dimensional (diamondoid) network consists of donor (bromide) and acceptor (CBr(4)) nodes alternately populated to result in the effective annihilation of centers of symmetry in agreement with the sphaleroid structural subclass.	Bromides	27-34	carbonyl reductase 4	Homo sapiens	146-152
14556310-0	2003	Ca(2+)-dependent and caspase-3-independent apoptosis caused by damage in Golgi apparatus due to 2,4,5,7-tetrabromorhodamine 123 bromide-induced photodynamic effects.	Bromides	128-135	caspase 3	Homo sapiens	21-30
12643282-8	2003	Bromide was the preferred substrate for eosinophil peroxidase, and chloride was not appreciably used even at a 1000-fold molar excess.	Bromides	0-7	eosinophil peroxidase	Homo sapiens	40-61
12641255-10	2003	Bromide was first detected in effluent after only 0.5 pore volumes of tap water had been added.	Bromides	0-7	nuclear RNA export factor 1	Homo sapiens	70-73
12612415-0	2003	Modification by fluoride, bromide, iodide, thiocyanate and nitrite anions of reaction of a myeloperoxidase-H2O2-Cl- system with nucleosides.	Bromides	26-33	myeloperoxidase	Homo sapiens	91-106
12269834-4	2002	At pH 7 and 15 degrees C, the two-electron reduction of compound I to native LPO by bromide and iodide has a second-order rate constant of (4.1 +/- 0.1) x 10(4) M(-1) s(-1) and (1.2 +/- 0.04) x 10(8) M(-1) s(-1), respectively.	Bromides	84-91	lactoperoxidase	Homo sapiens	77-80
12415426-2	2002	We have developed a routine ex vivo photometric phenotyping procedure based on the determination of bromide release rates from the hGSTT1-1-catalyzed glutathione conjugation of the substrate methyl bromide in EDTA blood samples under standard conditions (1,000 ppm methyl bromide, 10 min incubation).	Bromides	100-107	glutathione S-transferase theta 1	Homo sapiens	131-137
11329271-5	2001	Here, we show that EPO effectively uses plasma levels of bromide as a cosubstrate to brominate bases in nucleotides and double-stranded DNA, forming several stable novel brominated adducts.	Bromides	57-64	eosinophil peroxidase	Homo sapiens	19-22
12192697-2	2002	The diagnosis was confirmed by an increased bromide concentration > 20 mmoL.L-1.	Bromides	44-51	immunoglobulin kappa variable 1-16	Homo sapiens	79-82
11551198-4	2001	We have crystallized IGF-1 in the presence of the detergent deoxy big CHAPS, and determined its structure at 1.8 A resolution by multiwavelength anomalous diffraction, exploiting the anomalous scattering of a single bromide ion and six of the seven sulfur atoms of IGF-1.	Bromides	216-223	insulin like growth factor 1	Homo sapiens	21-26
12027628-1	2002	[reaction: see text] The specific silylation of aryl iodides and bromides with triethoxysilane (EtO)(3)SiH in the presence of NEt(3) and a catalytic amount of [Rh(cod)(MeCN)(2)]BF(4) provides the corresponding aryltriethoxysilanes in high yield.	Bromides	65-73	RUNX1 partner transcriptional co-repressor 1	Homo sapiens	96-99
11705390-0	2001	Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.	Bromides	79-86	myeloperoxidase	Homo sapiens	6-21
11705390-5	2001	The 1.9 A structures of the complexes formed by bromide (R = 0.215, R(free) = 0.270) and thiocyanate (R = 0.198, R(free) = 0.224) with the cyanide complex of myeloperoxidase show how the presence of bound cyanide alters the binding site for bromide in the distal heme cavity, while having little effect on thiocyanate binding.	Bromides	48-55	myeloperoxidase	Homo sapiens	158-173
11705390-5	2001	The 1.9 A structures of the complexes formed by bromide (R = 0.215, R(free) = 0.270) and thiocyanate (R = 0.198, R(free) = 0.224) with the cyanide complex of myeloperoxidase show how the presence of bound cyanide alters the binding site for bromide in the distal heme cavity, while having little effect on thiocyanate binding.	Bromides	241-248	myeloperoxidase	Homo sapiens	158-173
11681960-2	2001	A more general Pd(0) catalyst/ligand system has been developed that activates bromides and iodides: palladium(0) dibenzylideneacetone (Pd(dba)(2)) is activated with 2-(di-tert-butylphosphino)biphenyl (Buchwald"s ligand) (1:2 mol ratio of Pd/phosphine).	Bromides	78-86	loss of heterozygosity, 19, chromosomal region 1	Homo sapiens	138-141
11593004-7	2001	Furthermore, physiologic concentrations of bromide modulated the bactericidal effects of myeloperoxidase in vitro.	Bromides	43-50	myeloperoxidase	Mus musculus	89-104
11593004-8	2001	It seems, therefore, that myeloperoxidase can use bromide as well as chloride to produce oxidants in vivo, even though the extracellular concentration of bromide is at least 1,000-fold lower than that of chloride.	Bromides	50-57	myeloperoxidase	Mus musculus	26-41
11593004-8	2001	It seems, therefore, that myeloperoxidase can use bromide as well as chloride to produce oxidants in vivo, even though the extracellular concentration of bromide is at least 1,000-fold lower than that of chloride.	Bromides	154-161	myeloperoxidase	Mus musculus	26-41
11485572-5	2001	On the basis of these values thiocyanate is preferred 2.8-fold over bromide as a substrate for eosinophil peroxidase.	Bromides	68-75	eosinophil peroxidase	Homo sapiens	95-116
11485572-11	2001	We conclude that at plasma concentrations of bromide (20-120 microM) and thiocyanate (20-100 microM), hypobromous acid and oxidation products of thiocyanate are produced by eosinophil peroxidase.	Bromides	45-52	eosinophil peroxidase	Homo sapiens	173-194
11329272-0	2001	The eosinophil peroxidase-hydrogen peroxide-bromide system of human eosinophils generates 5-bromouracil, a mutagenic thymine analogue.	Bromides	44-51	eosinophil peroxidase	Homo sapiens	4-25
10864003-6	2000	In the presence of calcium reconstituted ICln channels are more permeable to bromide than chloride, and more permeable to potassium than sodium.	Bromides	77-84	chloride nucleotide-sensitive channel 1A pseudogene 1	Homo sapiens	41-45
10826917-3	2000	Iodide, bromide, thiocyanide and chloride effectively supplemented the MPO/H2O2 system, KI and NaCl being the most and the least effective supplements, respectively.	Bromides	8-15	myeloperoxidase	Sus scrofa	71-74
10766826-4	2000	Determination of the x-ray crystal structure of a myeloperoxidase-bromide complex (r = 0.243, free r = 0.296) has shown that this chloride ion can be replaced by bromide.	Bromides	66-73	myeloperoxidase	Homo sapiens	50-65
10766826-4	2000	Determination of the x-ray crystal structure of a myeloperoxidase-bromide complex (r = 0.243, free r = 0.296) has shown that this chloride ion can be replaced by bromide.	Bromides	162-169	myeloperoxidase	Homo sapiens	50-65
10766826-6	2000	The bromide-binding site in the distal cavity appears to be the halide-binding site responsible for shifts in the Soret band of the absorption spectrum of myeloperoxidase.	Bromides	4-11	myeloperoxidase	Homo sapiens	155-170
10836067-2	1999	A more general Pd(0)-catalyst/ligand system has been developed to activate bromides: palladium(II) acetate (Pd(OAc)2) is activated with triphenylphosphine (PPh3) or tri-o-tolylphosphine (P(o-tol)3) (1:2 molar ratio of Pd:phosphine).	Bromides	75-83	caveolin 1	Homo sapiens	156-160
12526463-0	2000	Kinetics of manganese(III) acetate in acetic acid: generation of Mn(III) with Co(III), Ce(IV), and dibromide radicals; reactions of Mn(III) with Mn(II), Co(II), hydrogen bromide, and alkali bromides.	Bromides	190-198	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	22-25
11272584-0	2000	Structural characterization of anti- and syn-allyltricarbonyliron bromide: rotational spectra, quadrupole coupling, and density functional calculations.	Bromides	66-73	synemin	Homo sapiens	41-44
11670978-6	1999	Room-temperature bulk oxidative electrolysis experiments reveal that the trans cation, generated in bulk solution from the (cis,mer)(+) and (cis,fac)(+) isomers, slowly ejects bromide with a rate constant of 1.6 x 10(-3) s(-1) to form trans-[Mn(CO)(2)(eta(2)-dpm)(2)](+).	Bromides	176-183	FA complementation group C	Homo sapiens	145-148
10825989-1	1999	[formula: see text] A strategy for assembling the two principal modules of epothilone B was developed that merges an allylic bromide with a terminal acetylene to fabricate the C10-C11 bond of the macrocycle.	Bromides	125-132	homeobox C10	Homo sapiens	176-179
10825989-1	1999	[formula: see text] A strategy for assembling the two principal modules of epothilone B was developed that merges an allylic bromide with a terminal acetylene to fabricate the C10-C11 bond of the macrocycle.	Bromides	125-132	RNA polymerase III subunit K	Homo sapiens	180-183
10452808-0	1999	A myeloperoxidase-specific assay based upon bromide-dependent chemiluminescence of luminol.	Bromides	44-51	myeloperoxidase	Homo sapiens	2-17
10452808-8	1999	Although EPX can also oxidize bromide to generate HOBr, activities of MPO and EPX can be distinguished at different pHs.	Bromides	30-37	eosinophil peroxidase	Homo sapiens	9-12
9062505-0	1997	Deuterium and bromide dilution, and bioimpedance spectrometry independently show that growth hormone-deficient adults have an enlarged extracellular water compartment related to intracellular water.	Bromides	14-21	growth hormone 1	Homo sapiens	86-100
9922160-0	1998	Reaction of myeloperoxidase compound I with chloride, bromide, iodide, and thiocyanate.	Bromides	54-61	myeloperoxidase	Homo sapiens	12-27
9922160-9	1998	SCN- is shown to be most effective in shifting the system myeloperoxidase/hydrogen peroxide from the peroxidatic cycle to the halogenation cycle, whereas iodide is shown to be more effective than bromide which in turn is much more effective than chloride.	Bromides	196-203	myeloperoxidase	Homo sapiens	58-73
10072228-2	1999	The Dead Sea, the lowest site on earth, is distinguished by natural oxygen enrichment, low humidity, high barometric pressure, and temperature with increased bromide and magnesium concentrations in the inspired air.	Bromides	158-165	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	9-12
10193578-3	1999	Chloride, iodide, bromide, and the thiocyanate anions were effective complements of the MPO/H2O2 system.	Bromides	18-25	myeloperoxidase	Equus caballus	88-91
9930748-11	1999	These cleaved forms of CSF tau consisted of the interior portion of the tau sequence, including the microtubule binding domain, as judged by cyanogen bromide digestion.	Bromides	150-157	microtubule associated protein tau	Homo sapiens	27-30
9930748-11	1999	These cleaved forms of CSF tau consisted of the interior portion of the tau sequence, including the microtubule binding domain, as judged by cyanogen bromide digestion.	Bromides	150-157	microtubule associated protein tau	Homo sapiens	72-75
9429599-0	1997	Expression of the proliferating cell nuclear antigen (PCNA) in the rat thyroid gland after exposure to bromide.	Bromides	103-110	proliferating cell nuclear antigen	Rattus norvegicus	18-52
9429599-0	1997	Expression of the proliferating cell nuclear antigen (PCNA) in the rat thyroid gland after exposure to bromide.	Bromides	103-110	proliferating cell nuclear antigen	Rattus norvegicus	54-58
9429599-1	1997	Analysis of expression of the proliferating cell nuclear antigen (PCNA) was used to determine the presumed hyperplastic character of morphological changes in the rat thyroid evoked by bromide administration.	Bromides	184-191	proliferating cell nuclear antigen	Rattus norvegicus	30-64
9429599-1	1997	Analysis of expression of the proliferating cell nuclear antigen (PCNA) was used to determine the presumed hyperplastic character of morphological changes in the rat thyroid evoked by bromide administration.	Bromides	184-191	proliferating cell nuclear antigen	Rattus norvegicus	66-70
9429599-8	1997	PCNA analysis showed that morphological changes resembling a parenchymatic goitre reflect a microfollicular rearrangement of the thyroid of rats exposed to bromide and have the character of hyperplasia owing to the increased mitotic activity of the follicular epithelium.	Bromides	156-163	proliferating cell nuclear antigen	Rattus norvegicus	0-4
9359420-1	1997	The neutrophil enzyme myeloperoxidase uses H2O2 to oxidize chloride, bromide, iodide and thiocyanate to their respective hypohalous acids.	Bromides	69-76	myeloperoxidase	Homo sapiens	22-37
9359420-6	1997	The relative specificity constants for chloride, bromide and thiocyanate were 1:60:730 respectively, indicating that thiocyanate is by far the most favoured substrate for myeloperoxidase.	Bromides	49-56	myeloperoxidase	Homo sapiens	171-186
9054574-9	1997	CA IV is also activated by low concentrations (<20 mM) of chloride, bromide, and phosphate.	Bromides	71-78	carbonic anhydrase 4	Homo sapiens	0-5
8931931-4	1996	From these results, we observed that a primary bromide produces a greater inhibition of 17 beta-HSD activity than secondary bromide, and that a shorter 16 alpha-side chain increases the inhibiting activity.	Bromides	47-54	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	88-99
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	92-99	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	24-44
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	92-99	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	46-52
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	92-99	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	170-176
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	92-99	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	170-176
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	257-264	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	24-44
9101035-11	1997	CDBM is a substrate for cytochrome P-450 2E1 (CYP2E1), as demonstrated by the inhibition of bromide and COHb formation due to simultaneous administration of CDBM and the CYP2E1 inhibitor diethyldithiocarbamate (DDTC); also by the initially higher levels of bromide in plasma and COHb in blood after gavage of CDBM pretreated with isoniazid (INH), an inducer of CYP2E1.	Bromides	257-264	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	46-52
8917596-3	1996	By coexpressing CLC-1 and CLC-2 in Xenopus oocytes, we now show the formation of novel CLC-1/CLC-2 heterooligomers that yield time-independent linear chloride currents with a chloride-->bromide-->iodide selectivity sequence.	Bromides	189-196	chloride channel, voltage-sensitive 1 S homeolog	Xenopus laevis	16-21
8917596-3	1996	By coexpressing CLC-1 and CLC-2 in Xenopus oocytes, we now show the formation of novel CLC-1/CLC-2 heterooligomers that yield time-independent linear chloride currents with a chloride-->bromide-->iodide selectivity sequence.	Bromides	189-196	chloride voltage-gated channel 2 S homeolog	Xenopus laevis	26-31
8917596-3	1996	By coexpressing CLC-1 and CLC-2 in Xenopus oocytes, we now show the formation of novel CLC-1/CLC-2 heterooligomers that yield time-independent linear chloride currents with a chloride-->bromide-->iodide selectivity sequence.	Bromides	189-196	chloride channel, voltage-sensitive 1 S homeolog	Xenopus laevis	87-92
8917596-3	1996	By coexpressing CLC-1 and CLC-2 in Xenopus oocytes, we now show the formation of novel CLC-1/CLC-2 heterooligomers that yield time-independent linear chloride currents with a chloride-->bromide-->iodide selectivity sequence.	Bromides	189-196	chloride voltage-gated channel 2 S homeolog	Xenopus laevis	93-98
9132963-7	1996	However, the low bromide partition test may associate also some other viral and other serous meningitides accompanied with severe lesions of the blood-brain barrier, resulting in increased passage of sodium bromide from the serum into the CSF, so that the serum/CSF ratio is lower.	Bromides	17-24	colony stimulating factor 2	Homo sapiens	239-242
9132963-7	1996	However, the low bromide partition test may associate also some other viral and other serous meningitides accompanied with severe lesions of the blood-brain barrier, resulting in increased passage of sodium bromide from the serum into the CSF, so that the serum/CSF ratio is lower.	Bromides	17-24	colony stimulating factor 2	Homo sapiens	262-265
9101035-12	1997	The increase of bromide formation after CDBM administration in phenobarbital (PB)-pretreated rats indicated that cytochrome P-450 2B1 and 2B2 (CYP2B1 and CYP2B2) play a role as catalysts of the CDBM biotransformation.	Bromides	16-23	cytochrome P450 2B1	Rattus norvegicus	113-141
9101035-12	1997	The increase of bromide formation after CDBM administration in phenobarbital (PB)-pretreated rats indicated that cytochrome P-450 2B1 and 2B2 (CYP2B1 and CYP2B2) play a role as catalysts of the CDBM biotransformation.	Bromides	16-23	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	143-149
9101035-12	1997	The increase of bromide formation after CDBM administration in phenobarbital (PB)-pretreated rats indicated that cytochrome P-450 2B1 and 2B2 (CYP2B1 and CYP2B2) play a role as catalysts of the CDBM biotransformation.	Bromides	16-23	cytochrome P450, family 2, subfamily b, polypeptide 2	Rattus norvegicus	154-160
9101035-13	1997	It is shown that m-xylene pretreatment, which activates CYP2E1 as well as CYP2Bs, leads to a higher bromide level after CDBM administration than the INH or PB pretreatment.	Bromides	100-107	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	56-62
8960369-3	1996	The myeloperoxidase could be replaced by lactoperoxidase in the system containing bromide, but not that containing chloride.	Bromides	82-89	myeloperoxidase	Mus musculus	4-19
8914592-3	1996	EPO could be specifically measured with o-phenylene diamine as chromogen at pH 8.0 in the presence of 3 mM bromide and MPO with tetramethylbenzidine as chromogen at pH 5.0 in the absence of bromide but with the EPO inhibitor, resorcinol.	Bromides	107-114	eosinophil peroxidase	Rattus norvegicus	0-3
8914592-3	1996	EPO could be specifically measured with o-phenylene diamine as chromogen at pH 8.0 in the presence of 3 mM bromide and MPO with tetramethylbenzidine as chromogen at pH 5.0 in the absence of bromide but with the EPO inhibitor, resorcinol.	Bromides	190-197	eosinophil peroxidase	Rattus norvegicus	0-3
8619607-1	1996	Eosinophil peroxidase and myeloperoxidase (MPO) catalyze the oxidation of bromide by hydrogen peroxide to produce hypobromous acid (HOBr).	Bromides	74-81	myeloperoxidase	Homo sapiens	26-41
8890325-3	1996	In neurons dialyzed with 10 mM QX-314 (bromide salt), the amplitude of the high-threshold Ca2+ current was on average 20% of that in control cells and the current-voltage relationships (I-Vs) were shifted in the positive voltage direction.	Bromides	39-51	carbonic anhydrase 2	Rattus norvegicus	90-93
8619607-1	1996	Eosinophil peroxidase and myeloperoxidase (MPO) catalyze the oxidation of bromide by hydrogen peroxide to produce hypobromous acid (HOBr).	Bromides	74-81	myeloperoxidase	Homo sapiens	43-46
8825615-5	1996	The virucidal effect of eosinophils, PMA, and bromide under these conditions is inhibited by the peroxidase inhibitor azide and catalase, but not heated catalase or superoxide dismutase, implicating the EPO-H2O2-halide system.	Bromides	46-53	catalase	Homo sapiens	128-136
8825615-5	1996	The virucidal effect of eosinophils, PMA, and bromide under these conditions is inhibited by the peroxidase inhibitor azide and catalase, but not heated catalase or superoxide dismutase, implicating the EPO-H2O2-halide system.	Bromides	46-53	eosinophil peroxidase	Homo sapiens	203-206
8825615-7	1996	When the EPO concentration is suboptimal, virucidal activity is increased by bromide, iodide, and, in this instance, thiocyanate and the virucidal activity of the bromide-supplemented system is inhibited by azide and catalase.	Bromides	77-84	eosinophil peroxidase	Homo sapiens	9-12
8825615-7	1996	When the EPO concentration is suboptimal, virucidal activity is increased by bromide, iodide, and, in this instance, thiocyanate and the virucidal activity of the bromide-supplemented system is inhibited by azide and catalase.	Bromides	163-170	eosinophil peroxidase	Homo sapiens	9-12
8825615-7	1996	When the EPO concentration is suboptimal, virucidal activity is increased by bromide, iodide, and, in this instance, thiocyanate and the virucidal activity of the bromide-supplemented system is inhibited by azide and catalase.	Bromides	163-170	catalase	Homo sapiens	217-225
18966441-3	1995	Selenium(VI) is rapidly reduced by bromide to Se(IV) which then forms 4,7-dibromo-5,6-benzopiazselenol (Br(2)-DAN-Se).	Bromides	35-42	NBL1, DAN family BMP antagonist	Homo sapiens	110-113
7756348-8	1995	For the iodine-mediated bromide translocation G0, tau and alpha exhibited no dependence on the applied clamp-voltage, which suggested that a square Nernst-Planck barrier limits the transport of the corresponding complex.	Bromides	24-31	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	46-63
7852368-0	1995	Oxidation of bromide by the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase.	Bromides	13-20	myeloperoxidase	Homo sapiens	52-67
7578334-5	1995	The specific binding of the bromide-ions with lysozyme molecules is revealed and possible binding sites are discussed.	Bromides	28-35	lysozyme	Homo sapiens	46-54
7852368-0	1995	Oxidation of bromide by the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase.	Bromides	13-20	eosinophil peroxidase	Homo sapiens	72-93
7852368-7	1995	In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine.	Bromides	46-53	myeloperoxidase	Homo sapiens	85-100
7852368-2	1995	Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds.	Bromides	69-76	myeloperoxidase	Homo sapiens	0-15
7852368-7	1995	In the presence of physiologic levels of both bromide (0.1 mM) and chloride (0.1 M), myeloperoxidase and eosinophil peroxidase produced mixtures of bromamines and chloramines containing 6 +/- 4% and 88 +/- 4% bromamine.	Bromides	46-53	eosinophil peroxidase	Homo sapiens	105-126
7852368-2	1995	Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds.	Bromides	69-76	eosinophil peroxidase	Homo sapiens	20-41
7852368-3	1995	Results were consistent with oxidation of bromide to an equilibrium mixture of hypobromous acid (HOBr) and hypobromite ion (OBr-).	Bromides	42-49	leptin receptor	Homo sapiens	98-101
7846736-7	1994	Thus, the introduction of a side-chain with a secondary bromide and a butyl methyl amide group at the 16 alpha-position of estradiol has two interesting effects; namely an inhibition of cytosolic 17 beta-HSD and a blockade of the estrogenic effect of estradiol.	Bromides	56-63	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	196-207
7843172-5	1994	Reversal potential revealed a permeability ratio of bromide with respect to chloride (PBr/PCl) of 1.51.	Bromides	52-59	translocator protein	Rattus norvegicus	86-89
8131215-3	1994	Myeloperoxidase-dependent degradation of hyaluronic acid is inhibited by superoxide dismutase, desferrioxamine, iodide ion, bromide ion, mannitol, histidine and various antiinflammatory agents.	Bromides	124-131	myeloperoxidase	Homo sapiens	0-15
1324677-9	1992	EPO, but not MPO, was partially protected against inactivation by adding physiologic levels of bromide along with chloride.	Bromides	95-102	eosinophil peroxidase	Homo sapiens	0-3
8100209-2	1993	By analysis of the type I collagen produced by cultured fibroblasts from the patient, the defect was mapped to alpha 1 cyanogen bromide peptide 7, a region corresponding to 271 amino acid residues of either the alpha 1(I) or alpha 2(I) collagen chains.	Bromides	128-135	collagen type I alpha 2 chain	Homo sapiens	225-244
8482389-0	1993	The structure of human carbonic anhydrase II in complex with bromide and azide.	Bromides	61-68	carbonic anhydrase 2	Homo sapiens	23-44
8482389-1	1993	The three-dimensional structure of human carbonic anhydrase II complexed with azide and with bromide was investigated crystallographically.	Bromides	93-100	carbonic anhydrase 2	Homo sapiens	41-62
8399771-1	1993	Perfluorooctylbromide (PFOB), a constituent component of gas-transporting fluorocarbon emulsions, liberates bromide ions when PFOB undergoes NADPH-dependent metabolism by liver microsomal monooxygenase.	Bromides	14-21	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	177-201
1400855-7	1992	Stability studies of chlorite showing the effectiveness of ethylenediamine as a preservative and summary data for an occurrence of nitrite, nitrate and the DBP precursor bromide are presented.	Bromides	170-177	D-box binding PAR bZIP transcription factor	Homo sapiens	156-159
18965468-1	1992	Adsorbed amounts of poly-l-lysine (pLys) and bromide ion on hydroxyapatite (HAp) from aqueous solutions of poly-l-lysine hydrobromide, and amounts of calcium and phosphate ions liberated concurrently from HAp during the adsorption of pLys were determined at 25 degrees .	Bromides	45-52	reticulon 3	Homo sapiens	76-79
1428133-4	1992	It is concluded that in doubtful cases with inconclusive CSF picture, a low bromide partition ratio is a strong reason for starting antituberculous treatment without any delay.	Bromides	76-83	colony stimulating factor 2	Homo sapiens	57-60
1319151-7	1992	Other halide ions are also found to inhibit the potato PPi-PFK: bromide is competitive like chloride, whereas fluoride and iodide have a mixed inhibition towards Fru 2,6-P2.	Bromides	64-71	pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha	Solanum tuberosum	55-62
2253299-0	1990	In vitro effects of fluoride and bromide on pseudocholinesterase and acetylcholinesterase activities.	Bromides	33-40	acetylcholinesterase (Cartwright blood group)	Homo sapiens	69-89
1601670-1	1992	11,17 beta-Dihydroxy-6-methyl-17 alpha-(3-[18F]fluoro-prop-1- ynyl)androsta-1,4,6-trien-3-one [( 18F]RU 52461), an 18F-analog of RU 28362, was synthesized by bromide displacement with [18F]fluoride in 12-30% overall radiochemical yield (decay-corrected) within 140 min from end of bombardment (EOB).	Bromides	158-165	PROP paired-like homeobox 1	Rattus norvegicus	54-60
1898006-2	1991	432, 57) on lactoperoxidase-catalyzed bromination of tyrosine and thyroglobulin stated, without evidence, that thyroid peroxidase (TPO) is able to use bromide as a substrate.	Bromides	151-158	thyroid peroxidase	Rattus norvegicus	111-129
1898006-2	1991	432, 57) on lactoperoxidase-catalyzed bromination of tyrosine and thyroglobulin stated, without evidence, that thyroid peroxidase (TPO) is able to use bromide as a substrate.	Bromides	151-158	thyroid peroxidase	Rattus norvegicus	131-134
1712984-3	1991	The sequence of anion selectivity of cAMP-regulated channels in cells containing either endogenous or recombinant CFTR was bromide greater than chloride greater than iodide greater than fluoride.	Bromides	123-130	CF transmembrane conductance regulator	Homo sapiens	114-118
1985118-0	1991	Bromide-dependent toxicity of eosinophil peroxidase for endothelium and isolated working rat hearts: a model for eosinophilic endocarditis.	Bromides	0-7	eosinophil peroxidase	Rattus norvegicus	30-51
15104210-8	2004	In contrast, bromide can support H2O2/MPO/halide apoptosis, but is less potent than chloride and it has no effect in the presence of physiological levels of chloride.	Bromides	13-20	myeloperoxidase	Homo sapiens	38-41
2154520-5	1990	Bromide or iodide caused up to a 7-fold increase in EPO activity and a 1.5-fold increase in MPO activity.	Bromides	0-7	eosinophil peroxidase	Homo sapiens	52-55
2154520-5	1990	Bromide or iodide caused up to a 7-fold increase in EPO activity and a 1.5-fold increase in MPO activity.	Bromides	0-7	myeloperoxidase	Homo sapiens	92-95
2154520-10	1990	Stimulation by bromide or iodide could be used to facilitate detection of EPO and to distinguish between MPO and EPO.	Bromides	15-22	eosinophil peroxidase	Homo sapiens	74-77
2154520-10	1990	Stimulation by bromide or iodide could be used to facilitate detection of EPO and to distinguish between MPO and EPO.	Bromides	15-22	myeloperoxidase	Homo sapiens	105-108
2154520-10	1990	Stimulation by bromide or iodide could be used to facilitate detection of EPO and to distinguish between MPO and EPO.	Bromides	15-22	eosinophil peroxidase	Homo sapiens	113-116
2538427-5	1989	Since the relative halogenating behavior of eosinophil peroxidase and neutrophil myeloperoxidase in this bromide range is essentially identical to that of the cells, the specificity of eosinophils toward bromide is intrinsic to eosinophil peroxidase and not to any special cellular properties.	Bromides	105-112	eosinophil peroxidase	Homo sapiens	44-65
34597631-3	2022	In this study, the bromide ion was found to have a stronger negative impact on 2,4,6-TCP degradation than chloride ion in the O3 system, and led to the formation of adsorbable organic halogens (AOX).	Bromides	19-26	acyl-CoA oxidase 1	Homo sapiens	194-197
34818816-6	2022	The presence of bromide ion facilitated NDMA generation during ozonation, but the reduction efficiency by O3/PMS slightly improved from 66.3% to 70.6%.	Bromides	16-23	proline rich protein BstNI subfamily 1	Homo sapiens	109-112
34246937-11	2021	As 200 mug/L of bromide was added to the water, bromate concentration increased significantly and then decreased as H2O2/O3 (g/g) increased and more H2O2 would be needed for bromate control.	Bromides	16-23	immunoglobulin kappa variable 2D-38 (pseudogene)	Homo sapiens	116-123
34633190-1	2021	We report herein an intermolecular syn-arylalkylation and alkenylalkylation of alkenyl amines with two different organohalides (iodides and bromides) using Ni(II) catalyst.	Bromides	140-148	synemin	Homo sapiens	35-38
34091342-7	2021	In the presence of bromide, O3/PMS process resulted in the formation of organic brominated oxidation by-products (OBPs), the concentration of which increased with increasing bromide dosage.	Bromides	19-26	proline rich protein BstNI subfamily 1	Homo sapiens	31-34
34091342-7	2021	In the presence of bromide, O3/PMS process resulted in the formation of organic brominated oxidation by-products (OBPs), the concentration of which increased with increasing bromide dosage.	Bromides	174-181	proline rich protein BstNI subfamily 1	Homo sapiens	31-34
34438259-7	2021	The only well-established physiological role of peroxidasin is in the formation of a sulfilimine bond, which cross-links collagen IV in basement membranes via catalyzed oxidation of bromide to hypobromous acid.	Bromides	182-189	peroxidasin	Homo sapiens	48-59
35388978-0	2022	Reducing the Trap Density in MAPbI3 Based Perovskite Solar Cells via Bromide Substitution.	Bromides	69-76	TRAP	Homo sapiens	13-17
35080224-2	2022	The reaction mainly produces a triboron complex 3 within 1 h, while a pair of B-O-B bridged trans-cis isomers 4 and 4" are formed as the reaction time elongates to 8 h. Moreover, two bromide products 4Br and 4Br" are prepared almost quantitatively by the bromination of 4 and 4", respectively.	Bromides	183-190	G protein-coupled receptor 15	Homo sapiens	78-83
2538427-5	1989	Since the relative halogenating behavior of eosinophil peroxidase and neutrophil myeloperoxidase in this bromide range is essentially identical to that of the cells, the specificity of eosinophils toward bromide is intrinsic to eosinophil peroxidase and not to any special cellular properties.	Bromides	105-112	myeloperoxidase	Homo sapiens	81-96
2538427-5	1989	Since the relative halogenating behavior of eosinophil peroxidase and neutrophil myeloperoxidase in this bromide range is essentially identical to that of the cells, the specificity of eosinophils toward bromide is intrinsic to eosinophil peroxidase and not to any special cellular properties.	Bromides	204-211	eosinophil peroxidase	Homo sapiens	228-249
20504478-4	1989	The results suggest that the bromide-induced formation of non-innervated postsynaptic membrane thickenings may promote the accumulation of A(12)AChE.	Bromides	29-36	acetylcholinesterase	Rattus norvegicus	144-148
3102490-7	1987	Salts of both chloride and bromide increased the affinity of Go alpha for GTP gamma S; fluoride and iodide were essentially ineffective.	Bromides	27-34	tripartite motif containing 47	Homo sapiens	61-69
2980812-3	1988	In certain patients there were very high CSF bromine levels, but this was shown to be the result of taking medications presented as bromide salts.	Bromides	132-145	colony stimulating factor 2	Homo sapiens	41-44
2838476-8	1988	The unique properties of eosinophil peroxidase are illustrated by the fact that at p2H 7.0 and with 100 microM bromide, eosinophil peroxidase generated 20 +/- 2% of the theoretical yield of singlet oxygen, whereas under identical conditions, myeloperoxidase and lactoperoxidase produced only 1.0 +/- 0.1% and -0.1 +/- 0.1%, respectively.	Bromides	111-118	eosinophil peroxidase	Homo sapiens	25-46
2838476-8	1988	The unique properties of eosinophil peroxidase are illustrated by the fact that at p2H 7.0 and with 100 microM bromide, eosinophil peroxidase generated 20 +/- 2% of the theoretical yield of singlet oxygen, whereas under identical conditions, myeloperoxidase and lactoperoxidase produced only 1.0 +/- 0.1% and -0.1 +/- 0.1%, respectively.	Bromides	111-118	eosinophil peroxidase	Homo sapiens	120-141
2838476-8	1988	The unique properties of eosinophil peroxidase are illustrated by the fact that at p2H 7.0 and with 100 microM bromide, eosinophil peroxidase generated 20 +/- 2% of the theoretical yield of singlet oxygen, whereas under identical conditions, myeloperoxidase and lactoperoxidase produced only 1.0 +/- 0.1% and -0.1 +/- 0.1%, respectively.	Bromides	111-118	myeloperoxidase	Homo sapiens	242-257
6282905-4	1982	Bromide and iodide were much more effective than chloride in the myeloperoxidase-mediated oxidation of methionine.	Bromides	0-7	myeloperoxidase	Canis lupus familiaris	65-80
6508849-12	1984	The data indicate that Tris-BP can be metabolized by rat liver microsomes to Bis-BP and 2-bromoacrolein catalyzed by cytochrome P-450 in a process liberating bromide ions.	Bromides	158-165	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	117-133
6697984-1	1984	The complete primary structure of mouse prolactin has been established on the basis of tryptic peptides from cyanogen-bromide-treated, S-carboxymethylated mouse prolactin and Staphylococcus-aureus-protease-cleaved overlaps, which were sequenced by manual liquid-phase and solid-phase Edman degradation.	Bromides	118-125	prolactin	Mus musculus	40-49
6817802-8	1982	The partial sequence of 51 residues of cyanogen-bromide peptides was sufficiently homologous to allow unambiguous overlap with the sequence of both human carbonic anhydrase I and II isozymes as well as with the recently published sequence of an apparent type I-like enzyme from the turtle.	Bromides	48-55	carbonic anhydrase 1	Homo sapiens	154-181
3514588-0	1986	Analysis of debromination of 1,2-dibromoethane by cytochrome P-450-linked hydroxylation systems as observed by bromide electrode.	Bromides	111-118	cytochrome P-450	Oryctolagus cuniculus	50-66
6373030-4	1984	Cytosolic metabolism of EDB, as measured by bromide ion release, was unaffected by deuterium substitution.	Bromides	44-51	vesicle-associated membrane protein 8	Rattus norvegicus	24-27
6921108-1	1982	Elongation factor Tu from Thermus thermophilus was coupled to cyanogen-bromide-activated Sepharose 4B and its properties were investigated.	Bromides	71-78	elongation factor Tu	Thermus thermophilus HB8	0-20
6281334-1	1982	The slow-reacting substance (SRS) bioactivity of leukotrienes C4 (LTC4) and D4 (LTD4) was rapidly decreased by incubation with eosinophil peroxidase (EPO), H2O2, and iodide, bromide, or to a lesser degree, chloride, LTB4 chemotactic activity was also decreased by the EPO-H2-H2-halide system, although at a slower rate.	Bromides	174-181	eosinophil peroxidase	Equus caballus	127-148
6272903-3	1981	When the non-bromide-containing cationic detergent cetyltrimethylammonium hydroxide (CTAOH) is used instead of CTAB, the eosinophils from MPO-deficient subjects are unable to decarboxylate L-alanine.	Bromides	13-20	myeloperoxidase	Homo sapiens	138-141
7068574-7	1982	From these changes and also changes in CD spectra, we deduced that fluoride, chloride, and bromide ions can bind with heme iron of the catalase molecule as ligands to form stable catalase-halide complexes, but iodide ions showed a different reactivity with catalase from other halides and may cause gross alteration in the structure or conformation of catalase.	Bromides	91-98	catalase	Homo sapiens	135-143
7068574-7	1982	From these changes and also changes in CD spectra, we deduced that fluoride, chloride, and bromide ions can bind with heme iron of the catalase molecule as ligands to form stable catalase-halide complexes, but iodide ions showed a different reactivity with catalase from other halides and may cause gross alteration in the structure or conformation of catalase.	Bromides	91-98	catalase	Homo sapiens	179-187
7068574-7	1982	From these changes and also changes in CD spectra, we deduced that fluoride, chloride, and bromide ions can bind with heme iron of the catalase molecule as ligands to form stable catalase-halide complexes, but iodide ions showed a different reactivity with catalase from other halides and may cause gross alteration in the structure or conformation of catalase.	Bromides	91-98	catalase	Homo sapiens	179-187
7068574-7	1982	From these changes and also changes in CD spectra, we deduced that fluoride, chloride, and bromide ions can bind with heme iron of the catalase molecule as ligands to form stable catalase-halide complexes, but iodide ions showed a different reactivity with catalase from other halides and may cause gross alteration in the structure or conformation of catalase.	Bromides	91-98	catalase	Homo sapiens	179-187
7041980-4	1982	Horse eosinophil peroxidase is a strongly basic protein with bacterial properties when combined with H2O2 and iodide, bromide or, to a lesser degree, chloride.	Bromides	118-125	eosinophil peroxidase	Equus caballus	6-27
7068574-8	1982	Dissociation constants (Kd) were estimated to be 2.5, 0.23, and 26 M for chloride, fluoride, and bromide complexes with catalase, respectively, and there is no heme-heme interaction during formation of the catalase-halide complexes as estimated from the Hill plot.	Bromides	97-104	catalase	Homo sapiens	120-128
6971825-1	1981	The trichloromethyl peroxy radical Cl3COO reacts with tryptophan, tryptophanyl-tyrosine and with lysozyme to form products whose overall absorption spectrum is different from those observed following the reaction of hydroxyl, bromide, thiocyanate or azide radicals.	Bromides	226-233	adhesion G protein-coupled receptor L3	Homo sapiens	35-38
7305262-0	1981	Discrepancies in bromide numbers during serum cholinesterase phenotyping.	Bromides	17-24	butyrylcholinesterase	Homo sapiens	46-60
6971825-1	1981	The trichloromethyl peroxy radical Cl3COO reacts with tryptophan, tryptophanyl-tyrosine and with lysozyme to form products whose overall absorption spectrum is different from those observed following the reaction of hydroxyl, bromide, thiocyanate or azide radicals.	Bromides	226-233	lysozyme	Homo sapiens	97-105
6987309-3	1980	When the EPO concentration of the reaction mixture was lowered, the bactericidal effect at pH 7.0 was lost first with chloride, then with bromide, and finally with iodide as the halide.	Bromides	138-145	erythropoietin	Cavia porcellus	9-12
7431182-2	1980	Three of 51 patients with a final diagnosis of TBM had a false negative serum to CSF bromide partition ratio of more than 1.6.	Bromides	85-92	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	47-50
6987309-1	1980	A partially purified preparation of guinea pig eosinophil peroxidase was found to be bactericidal when combined with H2O2 and either iodide, bromide, chloride, or thiocyanate ions.	Bromides	141-148	eosinophil peroxidase	Cavia porcellus	47-68
18961614-1	1975	A new method is presented for the quantitative separation and determination of selenium by direct evolution with the bromide-condensed phosphoric acid reagent (Br(-)-CPA) from rocks, marine sediments and plankton.	Bromides	117-124	carboxypeptidase A1	Homo sapiens	166-169
18961724-2	1975	The effects of the presence of bromide, the ratio of CAT to ammonia concentrations, the time for reaction and the pH of the reaction media are all significant in the quantitativeness of the reaction that occurs.	Bromides	31-38	catalase	Homo sapiens	53-56
33566622-1	2021	A general procedure of 1,2-dibromination of vicinal sp3 C-H bonds of arylethanes using N-bromosuccinimide as the bromide reagent without an external initiator has been established.	Bromides	113-120	Sp3 transcription factor	Homo sapiens	52-55
4317722-1	1970	Lactoperoxidase (EC 1.11.1.7) catalysed the oxidation of NADH by hydrogen peroxide in the presence of either thiocyanate, iodide or bromide.	Bromides	132-139	lactoperoxidase	Homo sapiens	0-15
14466443-3	1962	A system of kinetics was developed to show that a simple anion, chloride, bromide, or thiocyanate can inhibit an enzyme, prostatic acid phosphatase, in solution, both competitively with regard to substrate, and noncompetitively.	Bromides	74-81	acid phosphatase 3	Homo sapiens	121-147
13437463-0	1957	Interference of bromide in the Zak ferric chloride-sulfuric acid cholesterol method, and means of eliminating this interference.	Bromides	16-23	mitogen-activated protein kinase kinase kinase 20	Homo sapiens	31-34
33885298-7	2021	Unlike tetraphenylborate, the bromide counterion participates in a hydrogen-bonding interaction with the NH group, which influences the relative stability of the cis,anti and cis,syn isomers.	Bromides	30-37	synemin	Homo sapiens	179-182
4970226-1	1968	An antibacterial effect of myeloperoxidase, a halide, such as iodide, bromide, or chloride ion, and H(2)O(2) on Escherichia coli or Lactobacillus acidophilus is described.	Bromides	70-77	myeloperoxidase	Cavia porcellus	27-42
33538737-1	2021	With an increasing bromide content in CsPb(Br/Cl)3 perovskite nanocrystals (PNCs), the steady state photoluminescence quantum yield value increases from 28% to 50% to 76%.	Bromides	19-26	granzyme B	Homo sapiens	38-42
33153239-9	2020	The calculations indicate that CsPb(Br1-xClx)3 perovskite could be used in optical and optoelectronic devices by partly replacing bromide with chloride.	Bromides	130-137	granzyme B	Homo sapiens	31-35
33153239-9	2020	The calculations indicate that CsPb(Br1-xClx)3 perovskite could be used in optical and optoelectronic devices by partly replacing bromide with chloride.	Bromides	130-137	C-X-C motif chemokine ligand 11	Homo sapiens	36-39
32675287-1	2020	Peroxidasin is a heme peroxidase that oxidizes bromide to hypobromous acid (HOBr), a powerful oxidant that promotes the formation of the sulfilimine crosslink in collagen IV in basement membranes.	Bromides	47-54	peroxidasin	Mus musculus	0-11
32771689-7	2020	Increasing initial bromide level significantly enhanced THM and HAN concentrations, and therefore unknown TOX decreased.	Bromides	19-26	LOW QUALITY PROTEIN: thymocyte selection-associated high mobility group box protein TOX	Cricetulus griseus	106-109
32675287-6	2020	3-Bromotyrosine formed both during cell growth in culture and in the isolated decellularized extracellular matrix when embedded peroxidasin was supplied with hydrogen peroxide and bromide.	Bromides	180-187	peroxidasin	Mus musculus	128-139
32600038-8	2020	This finding is important to OGW-impacted source waters because drinking water plants with high-bromide source waters may switch to chloramination to meet DBP regulations.	Bromides	96-103	D-box binding PAR bZIP transcription factor	Homo sapiens	155-158
32574822-3	2020	As a consequence, bromide and iodide also played important roles in DBP formation.	Bromides	18-25	D-box binding PAR bZIP transcription factor	Homo sapiens	68-71
32574822-4	2020	The DBP yields in HA-containing water during UV/chlorination decreased in the order of iodide loaded > freshwater >> bromide loaded, whereas DBP formation in AOM-containing water decreased remarkably with halides added (freshwater > bromide loaded >> iodide loaded) at high UV fluence.	Bromides	117-124	D-box binding PAR bZIP transcription factor	Homo sapiens	4-7
32560625-7	2020	Bromide dampens the clock and glycolytic (Hk2 and Pkm2) gene expression rhythmicity in a dose-dependent manner.	Bromides	0-7	hexokinase 2	Rattus norvegicus	42-45
31352601-11	2020	Compared with NF270, NF90 can reject bromide and bromate more efficiently.	Bromides	37-44	interleukin enhancer binding factor 3	Homo sapiens	21-25
32571911-3	2020	The formation of sulfilimine cross-links depends on the ability of peroxidasin to use bromide and hydrogen peroxide substrates to produce hypobromous acid (HOBr).	Bromides	86-93	peroxidasin	Homo sapiens	67-78
32560625-7	2020	Bromide dampens the clock and glycolytic (Hk2 and Pkm2) gene expression rhythmicity in a dose-dependent manner.	Bromides	0-7	pyruvate kinase M1/2	Rattus norvegicus	50-54
31931310-5	2020	Both chlorine dose and bromide concentration significantly affected the formation of HAAs from BP-3 and SRHA during chlorination.	Bromides	23-30	BP3	Homo sapiens	95-99
32006828-5	2020	The addition of bromide increased average DBP yields by 50-70%.	Bromides	16-23	D-box binding PAR bZIP transcription factor	Homo sapiens	42-45
31931310-9	2020	The bromine incorporation factor (BIF) of the formed MHAAs, DHAAs and THAAs from SRHA and BP-3 both increased with the increasing bromide concentration in the following order: BIFDHAAs > BIFTHAAs > BIFMHAAs, indicating that bromine was easier to be incorporated into DHAAs rather than MHAAs or THAAs.	Bromides	130-137	BP3	Homo sapiens	90-94
31931310-8	2020	With the increasing bromide concentration, HAA formation from SRHA increased while that of BP-3 decreased.	Bromides	20-27	BP3	Homo sapiens	91-95
32290159-1	2020	Polymer nanocomposites have been synthesized by the covalent addition of bromide-functionalized graphene (Graphene-Br) through the single electron transfer-living radical polymerization technique (SET-LRP).	Bromides	73-80	LDL receptor related protein 1	Homo sapiens	201-204
31892405-9	2020	However, the rapid oxidation and incorporation of bromide appear to inhibit iodo-DBP formation under conditions relevant to drinking water treatment.	Bromides	50-57	D-box binding PAR bZIP transcription factor	Homo sapiens	81-84
32000127-3	2020	In a household cooking (e.g., soup making) process, a chlorine/monochloramine residual in tap water could react with bromide in edible salt and organic matter in food (e.g., rice, wheat) to form numerous brominated disinfection byproducts (Br-DBPs) at significant levels, which might induce adverse health effects to human beings.	Bromides	117-124	nuclear RNA export factor 1	Homo sapiens	90-93
31828539-3	2019	In this paper, the seasonal variations of bromide in WS1 and WS2 and THMs species in WTP1 and WTP2 were analyzed and compared.	Bromides	42-49	paired box 3	Homo sapiens	53-56
31708174-6	2020	The mean concentration of bromide in tap water samples was 46.2 mug/L.	Bromides	26-33	nuclear RNA export factor 1	Homo sapiens	37-40
31904056-0	2020	Hydride, chloride, and bromide show similar electronic effects in the Au9(PPh3)83+ nanocluster.	Bromides	23-30	caveolin 1	Homo sapiens	74-78
31904056-2	2020	We present electronic absorption spectra of precisely mass-selected Au9(PPh3)83+ clusters featuring a surface hydride, chloride, or bromide.	Bromides	132-139	caveolin 1	Homo sapiens	72-76
31828539-5	2019	Although the THMs concentrations in WTP1 were approximate to that in WTP2, the brominated THMs concentrations in WTP1 were higher than that in WTP2 due to higher bromide concentration in WS1 than WS2.	Bromides	162-169	paired box 3	Homo sapiens	187-190
31400591-7	2019	During chlorination, bromide-catalysis enhances the rate of the oxidation of Se(IV) to Se(VI) from 50% to nearly 90% with bromide concentrations of 50 mug L-1 and 200 mug L-1, respectively, at pH 7.0 and a chlorine dose of 2.0 mg L-1 (within 15 min).	Bromides	21-28	L1 cell adhesion molecule	Homo sapiens	155-174
31768432-1	2019	In this paper surfactant modified kaolin clay for As(III) and As(V) was prepared by intercalating hexadecyltrimethylamonium bromide (HDTMA-Br) cationic surfactant onto the clay interlayers.	Bromides	98-131	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	62-67
31768432-1	2019	In this paper surfactant modified kaolin clay for As(III) and As(V) was prepared by intercalating hexadecyltrimethylamonium bromide (HDTMA-Br) cationic surfactant onto the clay interlayers.	Bromides	133-141	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	62-67
31596594-6	2019	The morphology of FAA-3 was observed in the bromide (FAA-3-Br-) and hydroxide form (FAA-3-OH-) in dehydrated and hydrated conditions.	Bromides	44-51	transforming growth factor beta receptor 2	Homo sapiens	18-23
31033195-0	2019	Bromide alleviates fatty acid-induced lipid accumulation in mouse primary hepatocytes through the activation of PPARalpha signals.	Bromides	0-7	peroxisome proliferator activated receptor alpha	Mus musculus	112-121
30913326-0	2019	Selenolation of Aryl Iodides and Bromides Enabled by a Bench-Stable PdI Dimer.	Bromides	33-41	prolyl 4-hydroxylase subunit beta	Homo sapiens	68-71
31432578-1	2019	6-Methylenebicyclo[3.2.1]oct-1-en-3-one, a twisted and highly reactive enone, was prepared for the first time by elimination of its bromide precursor.	Bromides	132-139	solute carrier family 22 member 1	Homo sapiens	25-30
31141766-4	2019	Further it was found that the sensor is highly selective towards fluoride over other anions including chloride, bromide, iodide, nitrate, borate, perchlorate and can quantitatively detect fluoride at ppb level with a limit of detection of 0.02 mg/ L or 20 ppb.	Bromides	112-119	histatin 1	Homo sapiens	200-203
31033195-7	2019	We found that bromide decreased FFA-induced lipid accumulation and increased FFA-inhibited oxygen consumptions in mouse PHs in a dose-dependent manner via activation of PPARalpha.	Bromides	14-21	peroxisome proliferator activated receptor alpha	Mus musculus	169-178
31033195-8	2019	Mechanical studies demonstrated that bromide decreased the phosphorylation levels of JNK.	Bromides	37-44	mitogen-activated protein kinase 8	Mus musculus	85-88
31033195-9	2019	More importantly, the PPARalpha-specific inhibitor GW6471 partially abolished the beneficial effects of bromide on mouse PHs.	Bromides	104-111	peroxisome proliferator activated receptor alpha	Mus musculus	22-31
31033195-10	2019	Bromide alleviates FFA-induced excessive lipid storage and increases rates of FAO through the activation of PPARalpha/JNK signals in mouse PHs.	Bromides	0-7	peroxisome proliferator activated receptor alpha	Mus musculus	108-117
31033195-10	2019	Bromide alleviates FFA-induced excessive lipid storage and increases rates of FAO through the activation of PPARalpha/JNK signals in mouse PHs.	Bromides	0-7	mitogen-activated protein kinase 8	Mus musculus	118-121
30431281-0	2018	Nickel-Catalyzed Cyanation of Unactivated Alkyl Chlorides or Bromides with Zn(CN)2.	Bromides	61-69	carnosine dipeptidase 2	Homo sapiens	75-82
31333278-3	2019	Specifically, the chloride and bromide derivatives, [H(sebenzimMe)]2ZnX2 and [H(sebenzimMe)]2CdX2 (X = Cl, Br), exhibit two intramolecular N-H   X interactions, whereas the iodide derivatives, [H(sebenzimMe)]2ZnI2 and [H(sebenzimMe)]2CdI2, exhibit only one intramolecular N-H   I interaction.	Bromides	31-38	caudal type homeobox 2	Homo sapiens	93-97
30595207-0	2019	Environmental exposure of humans to bromide in the Dead Sea area: Measurement of genotoxicy and apoptosis biomarkers.	Bromides	36-43	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	56-59
30235603-9	2019	UTOX/TOX ratios were higher in treated low SUVA254 waters than raw waters having higher SUVA254 values, and they decreased with increasing initial bromide concentration in all sources.	Bromides	147-154	thymocyte selection associated high mobility group box	Homo sapiens	1-4
30431281-1	2018	A nickel-catalyzed cyanation of unactivated secondary alkyl chlorides or bromides using less toxic Zn(CN)2 as the cyanide source has been developed.	Bromides	73-81	carnosine dipeptidase 2	Homo sapiens	99-106
30431281-3	2018	Cyanation of primary alkyl chlorides or bromides was also achieved by reaction with Zn(CN)2 in the presence of n-Bu4NCl without the need of nickel catalyst.	Bromides	40-48	carnosine dipeptidase 2	Homo sapiens	84-91
30496567-7	2018	However, the rats challenged with NIMP or NEMP plus therapy with our novel Oxime 20 (either a bromide or a mesylate salt) showed GFAP levels statistically undistinguishable from controls.	Bromides	94-101	glial fibrillary acidic protein	Rattus norvegicus	129-133
30082031-1	2018	Myeloperoxidase (MPO) is the enzyme of azurophilic granules of neutrophils, which catalyzes two electron oxidation of either chloride or bromide in the so-called "halogenating cycle".	Bromides	137-144	myeloperoxidase	Homo sapiens	0-15
30199802-2	2018	Adsorbable organic halogen (AOX) is a parameter conventionally used to indicate the sum of organic halogenated disinfection byproducts (DBPs), which are formed from the reactions of disinfectants with dissolved organic matter, bromide and iodide in water.	Bromides	227-234	acyl-CoA oxidase 1	Homo sapiens	28-31
30095189-1	2018	The direct synthesis of organocalcium compounds (heavy Grignard reagents) by the reduction of organyl halides with activated calcium powder succeeded in a straightforward manner for organic bromides and iodides that are bound at sp2 -hybridized carbon atoms.	Bromides	190-198	Sp2 transcription factor	Homo sapiens	229-232
30082031-1	2018	Myeloperoxidase (MPO) is the enzyme of azurophilic granules of neutrophils, which catalyzes two electron oxidation of either chloride or bromide in the so-called "halogenating cycle".	Bromides	137-144	myeloperoxidase	Homo sapiens	17-20
29957358-1	2018	This paper evaluates the effect of various lyotropic anions (chloride, sulfate, perchlorate, iodide, nitrate, bromide) on the thermodynamic stability and dynamics of native cytochrome c (Cyt c) at pH 7.0.	Bromides	110-117	cytochrome c, somatic	Equus caballus	173-185
29957358-1	2018	This paper evaluates the effect of various lyotropic anions (chloride, sulfate, perchlorate, iodide, nitrate, bromide) on the thermodynamic stability and dynamics of native cytochrome c (Cyt c) at pH 7.0.	Bromides	110-117	cytochrome c, somatic	Equus caballus	187-192
29260872-2	2018	Exchange of the coordinating bromide anion for the more weakly coordinating triflate (OTf) or hexafluoroantimonate (SbF6) anions was accomplished by treatment with AgX or TlX salts to give compounds 1-3X; compounds 1OTf, 1SbF6, 2Br, 2OTf, 3Br, and 3SbF6 were all characterized by X-ray crystallography.	Bromides	29-36	CD46 molecule	Homo sapiens	171-174
29653357-1	2018	The Co(II)/peroxymonosulfate (Co(II)/PMS) process, producing sulfate radicals (SO4 -), effectively removes organic pollutants in water, while producing a significant amount of bromate (BrO3-) in the presence of bromide (Br-).	Bromides	211-218	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-28
29653357-1	2018	The Co(II)/peroxymonosulfate (Co(II)/PMS) process, producing sulfate radicals (SO4 -), effectively removes organic pollutants in water, while producing a significant amount of bromate (BrO3-) in the presence of bromide (Br-).	Bromides	211-218	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	30-40
29548389-3	2018	Moreover, the relationship between bromide concentration and DBP generation characteristics in processes was also analyzed.	Bromides	35-42	D-box binding PAR bZIP transcription factor	Homo sapiens	61-64
29207240-1	2018	(S)-(-)-Cotinine 2 undergoes direct and site-selective iridium-catalyzed borylation to provide boronate ester 3 and bromide 4 which offer flexible entry to a range of C(5)-substituted cotinine variants.	Bromides	116-123	complement C5	Homo sapiens	167-171
30052042-4	2018	The reaction is initiated by a syn-selective addition, affording cis-vinyl aziridine products after displacement of bromide.	Bromides	116-123	synemin	Homo sapiens	31-34
29626421-1	2018	Peroxidasin is a heme peroxidase that catalyses the oxidation of bromide by hydrogen peroxide to form an essential sulfilimine cross-link between methionine and hydroxylysine residues in collagen IV.	Bromides	65-72	peroxidasin	Homo sapiens	0-11
29400693-6	2018	EPO catalyzed oxidation of thiocyanate and bromide by H2O2 to generate oxidants that crosslink cysteine thiol groups and stiffen thiolated hydrogels.	Bromides	43-50	eosinophil peroxidase	Homo sapiens	0-3
29243762-0	2018	Mono- and dinuclear Ni(i) products formed upon bromide abstraction from the Ni(i) ring-expanded NHC complex [Ni(6-Mes)(PPh3)Br].	Bromides	47-54	protein phosphatase 4 catalytic subunit	Homo sapiens	119-123
28841423-6	2017	Product analysis showed that BDE-209 was mainly decomposed into lower brominated PBDEs, polybrominated dibenzofurans (PBDFs), hydroxylated PBDEs (OH-PBDEs), hydroxylated PBDFs (OH-PBDFs), bromophenols and bromide ions.	Bromides	205-212	homeobox D13	Homo sapiens	29-32
28774599-5	2017	The strong correlation between bromide concentration and the overall calculated DBP additive toxicity for both chlorinated and chloraminated source waters demonstrated that formation of brominated haloacetonitriles was the main contributor to toxicity.	Bromides	31-38	D-box binding PAR bZIP transcription factor	Homo sapiens	80-83
28570902-7	2017	The formation by UV/chlorine process started with the formation of free bromine (HOBr/OBr-) through the reaction of chlorine and bromide, followed by a subsequent oxidation of free bromine and formation of BrO and bromate by reacting with radicals.	Bromides	129-136	leptin receptor	Homo sapiens	82-85
27617999-1	2016	A water-soluble PdCl2(NH3)2/cationic 2,2"-bipyridyl system was found to be a highly efficient catalyst for Stille coupling of aryl iodides and bromides with organostannanes.	Bromides	143-151	phosducin like 2	Homo sapiens	16-21
27075937-4	2017	It was found that chloride and bromide in concentration above 80 mM and thiocyanate in concentration above 20 muM enhance catalase inhibition by nitrite and the nitroso compounds more than 100 times.	Bromides	31-38	catalase	Homo sapiens	122-130
29181221-1	2017	Monitoring bromides (Br-) is of crucial importance since bromates, potential human carcinogens, are formed during ozonation of water containing bromides in concentrations >100 mug L-1.	Bromides	11-19	immunoglobulin kappa variable 1-16	Homo sapiens	183-186
29181221-5	2017	Sensing of bromides was also explored in tap water after addition of bromides suggesting that herein prepared catalysts could be used for bromides detection in real samples.	Bromides	11-19	nuclear RNA export factor 1	Homo sapiens	41-44
29181221-5	2017	Sensing of bromides was also explored in tap water after addition of bromides suggesting that herein prepared catalysts could be used for bromides detection in real samples.	Bromides	69-77	nuclear RNA export factor 1	Homo sapiens	41-44
29181221-5	2017	Sensing of bromides was also explored in tap water after addition of bromides suggesting that herein prepared catalysts could be used for bromides detection in real samples.	Bromides	69-77	nuclear RNA export factor 1	Homo sapiens	41-44
27775741-2	2016	Structural characterization by single crystal X-ray diffraction indicates that compounds 1 and 3 are 5-coordinate complexes with both bromides bound to the Co(ii) ion, while compound 2 is square planar with one bromide in the outer coordination sphere.	Bromides	134-142	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	156-162
27775741-2	2016	Structural characterization by single crystal X-ray diffraction indicates that compounds 1 and 3 are 5-coordinate complexes with both bromides bound to the Co(ii) ion, while compound 2 is square planar with one bromide in the outer coordination sphere.	Bromides	134-141	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	156-162
27717045-4	2016	In the case of the C2-H tetrabenzoimidazolium-resorcinarene, the recognition region of the inorganic anions and hexanoate was located at the rim of the cavitand, although chloride and bromide also interacted with the aromatic C-H bonds located between adjacent arms of the cavitand.	Bromides	184-191	regulating synaptic membrane exocytosis 1	Homo sapiens	141-144
28774625-1	2017	Determination of halogen-specific total organic halogen (TOX) is vital for studies of disinfection of waters containing bromide, since total organic bromine (TOBr) is likely to be more problematic than total organic chlorine.	Bromides	120-127	thymocyte selection associated high mobility group box	Homo sapiens	57-60
28774625-3	2017	The optimised halogen-specific TOX method was validated based on the recovery of model compounds covering different classes of disinfection by-products (haloacetic acids, haloacetonitriles, halophenols and halogenated benzenes) and the recovery of total bromine (mass balance of TOBr and bromide concentrations) during disinfection of waters containing dissolved organic matter and bromide.	Bromides	288-295	thymocyte selection associated high mobility group box	Homo sapiens	31-34
28774625-3	2017	The optimised halogen-specific TOX method was validated based on the recovery of model compounds covering different classes of disinfection by-products (haloacetic acids, haloacetonitriles, halophenols and halogenated benzenes) and the recovery of total bromine (mass balance of TOBr and bromide concentrations) during disinfection of waters containing dissolved organic matter and bromide.	Bromides	382-389	thymocyte selection associated high mobility group box	Homo sapiens	31-34
28604855-1	2017	A novel P(NMe2)3-mediated formal carbon-halogen bond insertion of isatins into allylic and benzylic bromides/chlorides has been realized, leading to a facile synthesis of 3-halo 3,3"-disubstituted oxindoles.	Bromides	100-108	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	10-14
28561569-2	2017	For that, a strategic design and synthesis of three pentacoordinate CoII complexes [Co(bbp)Cl2] (MeOH) (1), [Co(bbp)Br2] (MeOH) (2), and [Co(bbp)(NCS)2] (3) has been achieved by using the tridentate coordination environment of the ligand in conjunction with the accommodating terminal ligands (i.e., chloride, bromide, and thiocyanate).	Bromides	310-317	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	68-72
28375546-3	2017	This transformation is catalyzed by strong acids in the presence of bromide or chloride salts and proceeds through simple SN 2 and elimination reactions.	Bromides	68-75	solute carrier family 38 member 5	Homo sapiens	122-126
28357871-1	2017	A novel, efficient, and facile protocol has been developed for transforming 2-hydroxybenzonitriles and bromides into a range of 3-aryl or alkyl substituted 1,2-benzisoxazoles in good to excellent yields mediated by PPh3.	Bromides	103-111	protein phosphatase 4 catalytic subunit	Homo sapiens	215-219
28024369-9	2016	Full tunability of the NPl emission wavelength is achieved by varying the halide ion used (bromide, iodide).	Bromides	91-98	N-acetylneuraminate pyruvate lyase	Homo sapiens	23-26
26490534-4	2016	Higher bromine substitution and incorporation factors for individual DBP classes were observed for the chlorinated water from the groundwater source (lower concentration of dissolved organic carbon (DOC)), which contained a higher concentration of bromide, than for the surface water source (higher DOC).	Bromides	248-255	D-box binding PAR bZIP transcription factor	Homo sapiens	69-72
26918248-3	2016	The Bi-chiral bromides R(C6F5)BiBr (3), R(Mes)BiBr (4), and R(Ph)BiBr (5) were obtained from RBiBr2 and C6F5MgBr, MesMgBr or PhMgBr, or from PhBiBr2 and RLi, in a 1 : 1 molar ratio.	Bromides	14-22	ATP binding cassette subfamily E member 1	Homo sapiens	153-156
26820223-8	2016	SIGNIFICANCE: The most effective drugs in patients with PCDH19 mutations were bromide and clobazam.	Bromides	78-85	protocadherin 19	Homo sapiens	56-62
27467860-7	2016	The bromide/DOC ratio was higher than the influent through much of the breakthrough curve (GAC does not remove bromide), which resulted in elevated brominated DBP concentrations in the effluent.	Bromides	4-11	D site-binding protein	Cricetulus griseus	159-162
28660022-4	2016	In the solid state, TK6+ hosts two bromide ions in its central cavity by forming six Csp2 -H hydrogen bonds.	Bromides	35-42	regulator of calcineurin 2	Homo sapiens	85-89
27078934-2	2016	The results showed that the concentration of BDE-28 (tri-BDE) in the gas-phase (three bromide components) was the highest, which was different from previous studies where BDE-99 and-47 were the predominant homologues in the gas-phase while the concentration of BDE-209 [(25.4 +- 124) pg   m-3] in particle-phase was the highest.	Bromides	86-93	homeobox D13	Homo sapiens	45-48
27078934-2	2016	The results showed that the concentration of BDE-28 (tri-BDE) in the gas-phase (three bromide components) was the highest, which was different from previous studies where BDE-99 and-47 were the predominant homologues in the gas-phase while the concentration of BDE-209 [(25.4 +- 124) pg   m-3] in particle-phase was the highest.	Bromides	86-93	homeobox D13	Homo sapiens	57-60
27078934-2	2016	The results showed that the concentration of BDE-28 (tri-BDE) in the gas-phase (three bromide components) was the highest, which was different from previous studies where BDE-99 and-47 were the predominant homologues in the gas-phase while the concentration of BDE-209 [(25.4 +- 124) pg   m-3] in particle-phase was the highest.	Bromides	86-93	homeobox D13	Homo sapiens	57-60
27078934-2	2016	The results showed that the concentration of BDE-28 (tri-BDE) in the gas-phase (three bromide components) was the highest, which was different from previous studies where BDE-99 and-47 were the predominant homologues in the gas-phase while the concentration of BDE-209 [(25.4 +- 124) pg   m-3] in particle-phase was the highest.	Bromides	86-93	homeobox D13	Homo sapiens	57-60
27078934-6	2016	Combined with the results of correlation analysis, this phenomenon might be ascribed to the ceased commercial production of penta- and octa-BDE, the light degradation of high bromide components and reduced concentrations of atmospheric particles in urban area.	Bromides	175-182	homeobox D13	Homo sapiens	140-143
26608216-3	2015	When compared with chloride and bromide, the higher electronegativity fluoride substituted derivatives significantly enhanced mitochondrial apoptosis pathway by remarkably increasing the expression of caspase-9 in HeLa cells.	Bromides	32-39	caspase 9	Homo sapiens	201-210
26183863-11	2016	Bromide was used in 40.63% of the SCN1A-positive patients and 20.69% of the SCN1A-negative patients, and its responder rates were 71.15% and 94.44% in SCN1A-positive and SCN1A-negative patients, respectively (P=0.05).	Bromides	0-7	sodium voltage-gated channel alpha subunit 1	Homo sapiens	34-39
26183863-11	2016	Bromide was used in 40.63% of the SCN1A-positive patients and 20.69% of the SCN1A-negative patients, and its responder rates were 71.15% and 94.44% in SCN1A-positive and SCN1A-negative patients, respectively (P=0.05).	Bromides	0-7	sodium voltage-gated channel alpha subunit 1	Homo sapiens	76-81
26183863-11	2016	Bromide was used in 40.63% of the SCN1A-positive patients and 20.69% of the SCN1A-negative patients, and its responder rates were 71.15% and 94.44% in SCN1A-positive and SCN1A-negative patients, respectively (P=0.05).	Bromides	0-7	sodium voltage-gated channel alpha subunit 1	Homo sapiens	76-81
26183863-11	2016	Bromide was used in 40.63% of the SCN1A-positive patients and 20.69% of the SCN1A-negative patients, and its responder rates were 71.15% and 94.44% in SCN1A-positive and SCN1A-negative patients, respectively (P=0.05).	Bromides	0-7	sodium voltage-gated channel alpha subunit 1	Homo sapiens	76-81
26183863-14	2016	SIGNIFICANCE: Bromide is most effective and is a well-tolerated drug among DS patients, especially among SCN1A-negative patients.	Bromides	14-21	sodium voltage-gated channel alpha subunit 1	Homo sapiens	105-110
26143270-5	2015	In the first step, apart from the known oxidation of bromide to free bromine and of free bromine to bromate by sulfate radicals (SO4(-)), Co(III) produced from the oxidation of Co(II) by PMS and SO4(-) also oxidizes bromide to free bromine.	Bromides	216-223	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	138-144
26143270-9	2015	Mathematical simulation further suggested that Co(III) outweighed SO4(-) to oxidize bromide to free bromine.	Bromides	84-91	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	47-53
26143270-5	2015	In the first step, apart from the known oxidation of bromide to free bromine and of free bromine to bromate by sulfate radicals (SO4(-)), Co(III) produced from the oxidation of Co(II) by PMS and SO4(-) also oxidizes bromide to free bromine.	Bromides	216-223	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	138-143
26143270-7	2015	In the presence of methanol, free bromine formation increased with increasing Co(II) dosage but no bromate was detected, indicating that Co(III) oxidized bromide to form free bromine but not bromate.	Bromides	154-161	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	78-83
26143270-7	2015	In the presence of methanol, free bromine formation increased with increasing Co(II) dosage but no bromate was detected, indicating that Co(III) oxidized bromide to form free bromine but not bromate.	Bromides	154-161	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	137-143
26143270-8	2015	In the presence of both EDTA and methanol, no free bromine or bromate was detected, as Co(III) was stabilized by EDTA to form the Co(III)EDTA(-) complex, which could not oxidize bromide.	Bromides	178-185	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	90-93
25555037-5	2015	Rates of SN1 solvolyses of benzhydryl chlorides, bromides, and tosylates derived from E(13-33)(+), i.e., from highly reactive carbocations, correlate excellently with the corresponding Lewis acidities and the quantum chemically calculated methyl anion affinities.	Bromides	49-57	solute carrier family 38 member 3	Homo sapiens	9-12
25762223-13	2015	Only the chlorinating activity of EPO is efficiently inhibited by CP, while the capacity of EPO to oxidize bromide and thiocyanate practically does not depend on the presence of CP.	Bromides	107-114	eosinophil peroxidase	Homo sapiens	92-95
26329271-14	2015	Calorimetric titrations of the syn isomer with bromide confirmed the strong halogen-bond donor strength of the former (K   4 x 10(6) M(-1), DeltaG   38 kJ/mol).	Bromides	47-54	synemin	Homo sapiens	31-34
26176378-1	2015	A commercial phosphorus-based reagent (P(NMe2)3) mediates umpolung alkylation of methyl aroylformates with benzylic and allylic bromides, leading to either Barbier-type addition or ylide-free olefination products upon workup.	Bromides	128-136	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	41-45
25766632-5	2015	Aminolysis of the gamma-lactones 14c and 14e with benzylamines provided the gamma-hydroxybutanamides 15c-e, which were converted into the bromides 11c-e by an Appel reaction using polymer-bound PPh3.	Bromides	138-146	protein phosphatase 4 catalytic subunit	Homo sapiens	194-198
25472496-2	2014	These formal SN-type reactions generate valuable (hetero)aryl/alkenyl nitriles, iodides, and bromides as well as allylated indoles using a bench-stable Co(III) catalyst.	Bromides	93-101	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	152-159
25331425-3	2015	After improving the protein purification yield and stability, which had so far limited the biochemical characterization of hSR, we found that the catalytic activity is affected by halides, in the order fluoride > chloride > bromide.	Bromides	230-237	HSR	Homo sapiens	123-126
25670974-4	2014	Thus obtained key-intermediates were further transformed into bromide derivatives by means of PBr3, and subsequently reacted with appropriate amine providing desired pharmacologically valuable (R)- and (S)-stereoisomers of title drugs in an ee range of 84-98%, respectively.	Bromides	62-69	E2F transcription factor 1	Homo sapiens	94-98
24637450-8	2014	Bromides, ammonium and phosphate were the main species in water sorption samples for PCB pyrolysis exhaust.	Bromides	0-8	pyruvate carboxylase	Homo sapiens	85-88
24632415-7	2014	Bromide, iodide and sulfite also protected GSTZ1 from inactivation by DCA, however fluoride, sulfate, carbonate, acetate, cyanide did not.	Bromides	0-7	glutathione S-transferase zeta 1	Homo sapiens	43-48
24632415-8	2014	Protection by bromide varied by GSTZ1 haplotype: EC50 was 1.3+-0.3mM for the EGT haplotype and 5.0+-0.60mM for the KRT haplotype.	Bromides	14-21	glutathione S-transferase zeta 1	Homo sapiens	32-37
24632415-8	2014	Protection by bromide varied by GSTZ1 haplotype: EC50 was 1.3+-0.3mM for the EGT haplotype and 5.0+-0.60mM for the KRT haplotype.	Bromides	14-21	keratin 126, pseudogene	Homo sapiens	115-118
24476084-1	2014	In this work, we show that the unique combination of a nickel catalyst and Cp2TiCl allows the direct conjugate addition of aryl and alkenyl iodides, bromides, and to a lesser extent, chlorides and triflates to alpha,beta-unsaturated carbonyls at room temperature, without requiring the previous formation of an organometallic nucleophile.	Bromides	149-157	ceruloplasmin	Homo sapiens	75-78
24356583-1	2014	The APEX software predicts the photochemical transformation kinetics of xenobiotics in surface waters as a function of: photoreactivity parameters (direct photolysis quantum yield and second-order reaction rate constants with transient species, namely  OH, CO3(-) , (1)O2 and the triplet states of chromophoric dissolved organic matter, (3)CDOM*), water chemistry (nitrate, nitrite, bicarbonate, carbonate, bromide and dissolved organic carbon, DOC), and water depth (more specifically, the optical path length of sunlight in water).	Bromides	407-414	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	4-8
24261546-4	2014	For each substrate, only 1.05 equiv of NBS was necessary to fully transform the benzylic starting material into the corresponding bromide.	Bromides	130-137	nibrin	Homo sapiens	39-42
24176694-0	2014	Examining the interrelationship between DOC, bromide and chlorine dose on DBP formation in drinking water--a case study.	Bromides	45-52	D-box binding PAR bZIP transcription factor	Homo sapiens	74-77
23472833-6	2013	We show that the salts when ordered by heat effects produced by mixing of NaF and NaBr with 3,3-, 6,9-, or 6,12-ionene fluorides and bromides follow the opposite ordering than in the case when the same alkali halide salts are mixed with more hydrophobic 12,12-ionene salts.	Bromides	133-141	C-X-C motif chemokine ligand 8	Homo sapiens	74-77
24087851-3	2013	Moreover, the dimerization of tertiary bromide 6 efficiently establishes sterically hindered vicinal quaternary carbons (C3a and C3a"), which is a key linkage of intriguing bispyrrolo[2,3-b]indoline alkaloids, thereby enabling us to complete the total syntheses of racemic chimonanthine (9) and folicanthine (10).	Bromides	39-46	complement C3	Homo sapiens	121-124
24087851-3	2013	Moreover, the dimerization of tertiary bromide 6 efficiently establishes sterically hindered vicinal quaternary carbons (C3a and C3a"), which is a key linkage of intriguing bispyrrolo[2,3-b]indoline alkaloids, thereby enabling us to complete the total syntheses of racemic chimonanthine (9) and folicanthine (10).	Bromides	39-46	complement C3	Homo sapiens	129-132
23756368-3	2013	The incorporation of a bromide at the 5-position of the pyrimidine core and in combination with a 1,2-dimethylpiperazine pendant domain yielded a lead compound with potent PAK1 inhibition and anti-proliferative activity in various colon cancer cell lines.	Bromides	23-30	p21 (RAC1) activated kinase 1	Homo sapiens	172-176
23641004-4	2013	We show that, in LeuT-E290S cocrystallized with bromide or chloride, the anion is coordinated by side chain hydroxyls from Tyr47, Ser290, and Thr254 and the side chain amide of Gln250.	Bromides	48-55	Leucine transport, high	Homo sapiens	17-21
23487259-0	2013	Hydrogen bonded anion ribbons, networks and clusters and sulfur-anion interactions in novel radical cation salts of BEDT-TTF with sulfamate, pentaborate and bromide.	Bromides	157-164	ras homolog family member H	Homo sapiens	121-124
23487259-5	2013	Two new bromide salts of BEDT-TTF are reported, one is a semiconducting 1 : 1 salt in which the bromide is integrated among the BEDT-TTF donors, while the other contain a square of four bromide ions linked together by hydrogen bonding to a centrally located H5O2(+) cation for every five BEDT-TTF molecules.	Bromides	8-15	ras homolog family member H	Homo sapiens	30-33
23487259-5	2013	Two new bromide salts of BEDT-TTF are reported, one is a semiconducting 1 : 1 salt in which the bromide is integrated among the BEDT-TTF donors, while the other contain a square of four bromide ions linked together by hydrogen bonding to a centrally located H5O2(+) cation for every five BEDT-TTF molecules.	Bromides	8-15	ras homolog family member H	Homo sapiens	133-136
23487259-5	2013	Two new bromide salts of BEDT-TTF are reported, one is a semiconducting 1 : 1 salt in which the bromide is integrated among the BEDT-TTF donors, while the other contain a square of four bromide ions linked together by hydrogen bonding to a centrally located H5O2(+) cation for every five BEDT-TTF molecules.	Bromides	8-15	ras homolog family member H	Homo sapiens	133-136
23487259-5	2013	Two new bromide salts of BEDT-TTF are reported, one is a semiconducting 1 : 1 salt in which the bromide is integrated among the BEDT-TTF donors, while the other contain a square of four bromide ions linked together by hydrogen bonding to a centrally located H5O2(+) cation for every five BEDT-TTF molecules.	Bromides	96-103	ras homolog family member H	Homo sapiens	30-33
23487259-5	2013	Two new bromide salts of BEDT-TTF are reported, one is a semiconducting 1 : 1 salt in which the bromide is integrated among the BEDT-TTF donors, while the other contain a square of four bromide ions linked together by hydrogen bonding to a centrally located H5O2(+) cation for every five BEDT-TTF molecules.	Bromides	96-103	ras homolog family member H	Homo sapiens	30-33
23635146-1	2013	The valence ionization spectra covering the binding energy range 0-45 eV of alkali bromide XBr (X = Li, Na, K, Rb) vapors are studied within the framework of the propagator theory.	Bromides	83-90	RE1 silencing transcription factor	Homo sapiens	91-94
23351431-5	2013	Complete conversion of iodide to iodate while minimizing the bromate formation to below the guideline value of 10 mug L-1 was achieved for a wide range of ozone doses in five raw waters with DOC and bromide concentrations of 1.1-20 mg L-1 and 170-940 mug L-1, respectively.	Bromides	199-206	immunoglobulin kappa variable 1-16	Homo sapiens	118-121
25864331-9	2014	This method could also be used for the determination of OCI- and OBr- ions produced during the enzymatic oxidation of chloride and bromide by mammalian"s peroxidases.	Bromides	131-138	leptin receptor	Homo sapiens	56-68
23953089-10	2013	Model results show that reaction with Br2( -) could be a potentially important transformation pathway of BP-4 in bromide-rich (e.g. seawater) and DOM-rich environments.	Bromides	113-120	BP4	Homo sapiens	105-109
23471296-5	2013	We find that chloride and bromide inhibit heterologously expressed TRPM7 in synergy with intracellular Mg(2+) ([Mg(2+)]i) and this is facilitated through the ATP-binding site of the channel"s kinase domain.	Bromides	26-33	transient receptor potential cation channel subfamily M member 7	Homo sapiens	67-72
23323704-1	2013	HOBr, formed via oxidation of bromide by free available chlorine (FAC), is frequently assumed to be the sole species responsible for generating brominated disinfection byproducts (DBPs).	Bromides	30-37	FA complementation group C	Homo sapiens	66-69
23323704-2	2013	Our studies reveal that BrCl, Br(2), BrOCl, and Br(2)O can also serve as brominating agents of the herbicide dimethenamid in solutions of bromide to which FAC was added.	Bromides	138-145	FA complementation group C	Homo sapiens	155-158
22231588-3	2012	We used isothermal titration calorimetry to measure the enthalpies of mixing, DeltaH(mix), of 3,3- and 6,6-ionene fluorides and bromides with low molecular weight salts (NaF, NaCl, NaBr, and NaI) at 298 K in water.	Bromides	128-136	C-X-C motif chemokine ligand 8	Homo sapiens	170-173
23026126-6	2012	Furthermore, the effect of the presence of bromide on DBP formation was investigated and found to follow the same pH dependency as without bromide present, with the overall DBP formation increasing, except for HAAs.	Bromides	43-50	D-box binding PAR bZIP transcription factor	Homo sapiens	54-57
23026126-6	2012	Furthermore, the effect of the presence of bromide on DBP formation was investigated and found to follow the same pH dependency as without bromide present, with the overall DBP formation increasing, except for HAAs.	Bromides	43-50	D-box binding PAR bZIP transcription factor	Homo sapiens	173-176
23026126-7	2012	Estimation of genotoxicity and cytotoxicity of the chlorinated human exudates showed that among the quantified DBP groups, HAN formation were responsible for the majority of the toxicity from the measured DBPs in both absence and presence of bromide.	Bromides	242-249	D-box binding PAR bZIP transcription factor	Homo sapiens	111-114
22982576-3	2012	Phagocyte-derived myeloperoxidase (MPO) utilizes chloride and bromide, in the presence of hydrogen peroxide (H(2)O(2)), to generate hypochlorous acid and hypobromous acid, potent oxidizing species that are known to kill invading pathogens.	Bromides	62-69	myeloperoxidase	Homo sapiens	35-38
22718769-9	2012	Here the dye well reflected the different substrate specificities of myeloperoxidase and eosinophil peroxidase regarding chloride and bromide.	Bromides	134-141	myeloperoxidase	Homo sapiens	69-84
22703526-4	2012	The syn iodo-imidazoliophane isomer forms novel dimeric isostructural XB complexes of 2:2 stoichiometry with bromide and iodide anions in the solid state.	Bromides	109-116	synemin	Homo sapiens	4-7
22703526-6	2012	(1)H NMR and fluorescence spectroscopic titration experiments with a variety of anions in the competitive CD(3)OD/D(2)O (9:1) aqueous solvent mixture demonstrated the bromo- and syn iodo-imidazoliophane XB receptors to bind selectively iodide and bromide respectively, and sense these halide anions exclusively via a fluorescence response.	Bromides	247-254	synemin	Homo sapiens	178-181
22703526-8	2012	Computational DFT and molecular dynamics simulations corroborate the experimental observations that bromo- and syn iodo-imidazoliophane XB receptors form stable cooperative convergent XB associations with bromide and iodide.	Bromides	205-212	synemin	Homo sapiens	111-114
22402131-0	2012	A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.	Bromides	150-157	protein tyrosine kinase 2	Homo sapiens	17-38
22402131-0	2012	A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.	Bromides	150-157	protein tyrosine kinase 2	Homo sapiens	40-43
22402131-3	2012	Using these approaches, we identified 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide, called Y11, a small molecule inhibitor targeting Y397 site of FAK.	Bromides	111-118	protein tyrosine kinase 2	Homo sapiens	182-185
22417233-0	2012	Direct arylation of imidazo[1,2-a]pyridine at C-3 with aryl iodides, bromides, and triflates via copper(I)-catalyzed C-H bond functionalization.	Bromides	69-77	complement C3	Homo sapiens	46-49
22430156-0	2012	Bromide in patients with SCN1A-mutations manifesting as Dravet syndrome.	Bromides	0-7	sodium voltage-gated channel alpha subunit 1	Homo sapiens	25-30
22430156-1	2012	We report a retrospective analysis of bromide therapy in 32 patients suffering from Dravet syndrome with SCN1A-mutations who received bromide.	Bromides	38-45	sodium voltage-gated channel alpha subunit 1	Homo sapiens	105-110
22430156-6	2012	We conclude that bromide holds promise in patients with SCN1A-mutations suffering from Dravet syndrome.	Bromides	17-24	sodium voltage-gated channel alpha subunit 1	Homo sapiens	56-61
22033307-6	2011	The presence of bromide increased the formation of brominated TOX but did not significantly affect total TOX formation, in spite of the fact that it reduced hydroxyl radical levels.	Bromides	16-23	thymocyte selection associated high mobility group box	Homo sapiens	62-65
21239206-8	2011	The ultrasonic degradation of 4-CyP was clearly promoted in the presence of bromide anions and the promoting effect on degradation increased with increasing bromide concentration.	Bromides	76-83	peptidylprolyl isomerase G	Homo sapiens	32-35
21239206-8	2011	The ultrasonic degradation of 4-CyP was clearly promoted in the presence of bromide anions and the promoting effect on degradation increased with increasing bromide concentration.	Bromides	157-164	peptidylprolyl isomerase G	Homo sapiens	32-35