PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3778735-0 1986 Use of polyethylene-lined silicone rubber cannulae in long-term insulin infusion in the dog. Silicones 26-34 insulin Canis lupus familiaris 64-71 3734663-3 1986 The amount of nsLTP (SCP2) in testis tissue increased twofold 48 h after two daily injections of human chorionic gonadotrophin (100 i.u., s.c.) and decreased twofold after plasma luteinizing hormone levels were suppressed to almost undetectable levels with silicone elastomer implants containing testosterone. Silicones 257-265 sterol carrier protein 2 Homo sapiens 14-19 3734663-3 1986 The amount of nsLTP (SCP2) in testis tissue increased twofold 48 h after two daily injections of human chorionic gonadotrophin (100 i.u., s.c.) and decreased twofold after plasma luteinizing hormone levels were suppressed to almost undetectable levels with silicone elastomer implants containing testosterone. Silicones 257-265 sterol carrier protein 2 Homo sapiens 21-25 6532162-4 1984 The author"s technique (1974) of forward projection of the lower nasal base with a transverse silicone implant for patients with a negative tip-dorsum relationship is described. Silicones 94-102 TOR signaling pathway regulator Homo sapiens 140-143 3859689-1 1985 The implantation of silicone capsules that contained estrone and that were adjacent to grafts of anterior pituitary tissue in the spleens of adrenalectomized glucocorticoid-deficient inbred F344 rats resulted in high circulating prolactin (Prl) levels without the untoward effects of chronic hyperestrogenism or of grafts of Prl-secreting pituitary tumors. Silicones 20-28 prolactin Rattus norvegicus 229-238 3859689-1 1985 The implantation of silicone capsules that contained estrone and that were adjacent to grafts of anterior pituitary tissue in the spleens of adrenalectomized glucocorticoid-deficient inbred F344 rats resulted in high circulating prolactin (Prl) levels without the untoward effects of chronic hyperestrogenism or of grafts of Prl-secreting pituitary tumors. Silicones 20-28 prolactin Rattus norvegicus 240-243 3859689-1 1985 The implantation of silicone capsules that contained estrone and that were adjacent to grafts of anterior pituitary tissue in the spleens of adrenalectomized glucocorticoid-deficient inbred F344 rats resulted in high circulating prolactin (Prl) levels without the untoward effects of chronic hyperestrogenism or of grafts of Prl-secreting pituitary tumors. Silicones 20-28 prolactin Rattus norvegicus 325-328 4007468-5 1985 From the experiences collected so far with 10 cases, it can be concluded that the rectus flap is a valuable alternative to the latissimus dorsi flap and to reconstruction with silicone protheses. Silicones 176-184 arachidonate 5-lipoxygenase activating protein Homo sapiens 89-93 3993833-0 1985 Peri-articular reactions to microscopic erosion of silicone-polymer implants. Silicones 51-59 perilipin 1 Homo sapiens 0-4 3897545-2 1985 Anti-C1q F(ab")2 fragments were immobilized on silicone rubber and after the interaction of anti-C1q with C1q, Fab" fragments of anti-C1q coupled with beta-D-galactosidase were added. Silicones 47-55 complement C1q A chain Homo sapiens 5-8 6733221-0 1984 Adsorption of bovine submaxillary mucin on silicone contact lenses grafted with poly(vinyl pyrrolidone). Silicones 43-51 mucin 1, cell surface associated Bos taurus 34-39 6733221-3 1984 In situ adsorption of the bovine submaxillary mucin on silicone contact lenses ungrafted and grafted with poly(vinyl pyrrolidone) was performed for the first time using an original radiotracer technique. Silicones 55-63 mucin 1, cell surface associated Bos taurus 46-51 6733221-5 1984 Desorption experiments reveal that in addition to the tightly adsorbed protein layer, a loosely bound mucin layer of the same thickness exists on grafted and ungrafted silicones. Silicones 168-177 mucin 1, cell surface associated Bos taurus 102-107 6326599-7 1984 In rats implanted subcutaneously with silicone rubber impregnated with DOCA, Bmax for 125I-ANG II was significantly increased (to 142 +/- 4 fmol/mg), whereas rats receiving 1% NaCl in their drinking water had no change in binding capacity, although PRA was lower in both groups. Silicones 38-46 angiotensinogen Rattus norvegicus 91-97 6827346-7 1983 This study demonstrates that MCA trunk occlusion by silicone cylinder embolization produces a more marked decrease in deep CBF, with diminution of SEP and increase in ICP, than that produced by trapping. Silicones 52-60 CCAAT/enhancer binding protein zeta Rattus norvegicus 123-126 6814792-1 1982 A sandwich enzyme immunoassay for the measurement of human growth hormone in serum was developed using antibody IgG-beta-D-galactosidase conjugate and antibody IgG-coated silicone rubber rods. Silicones 171-179 growth hormone 1 Homo sapiens 59-73 7416082-2 1980 An increase in the occurrence of false-positive assays for C5a and C3 conversion, combined with hemolytic C assays discrepant between two laboratories, led to the suspicion that serum tubes with silicone separators might activate complement. Silicones 195-203 complement C5a receptor 1 Homo sapiens 59-69 6454436-0 1981 The titanium/silicone rubber clip for female sterilization. Silicones 13-21 CAP-Gly domain containing linker protein 1 Homo sapiens 29-33 6454436-1 1981 A composite titanium/silicone rubber clip has been developed for female sterilization. Silicones 21-29 CAP-Gly domain containing linker protein 1 Homo sapiens 37-41 6454436-2 1981 The 12.7 mm long metal clip is lined with silicone rubber and is bent round the Fallopian tube by means of an applicator that can be used laparoscopically. Silicones 42-50 CAP-Gly domain containing linker protein 1 Homo sapiens 23-27 397069-8 1979 2) Another method using human thyroglobulin conjugated with beta-D-galactosidase and silicone rod coated with human thyroglobulin was developed for the measurement of circulating (anti-human thyroglobulin) autoantibody. Silicones 85-93 thyroglobulin Homo sapiens 116-129 6993148-1 1980 This paper describes a miniature precision peristaltic pump and a silicone rubber reservoir developed for the infusion of insulin in diabetic subjects. Silicones 66-74 insulin Homo sapiens 122-129 7417594-4 1980 Thus AT III and heparin were co-immobilized on Sepharose 4B, polyvinyl alcohol, polyhydroxy-ethyl methacrylate and silicone-coated nylon by the cyanogen bromide procedure. Silicones 115-123 serpin family C member 1 Homo sapiens 5-11 397069-8 1979 2) Another method using human thyroglobulin conjugated with beta-D-galactosidase and silicone rod coated with human thyroglobulin was developed for the measurement of circulating (anti-human thyroglobulin) autoantibody. Silicones 85-93 thyroglobulin Homo sapiens 116-129 110495-1 1979 We describe a "sandwich-type" enzyme immunoassay for insulin in serum, in which antibody Fab"-beta-D-galactosidase conjugate and an antibody-immobilized silicone rubber solid-phase are used. Silicones 153-161 insulin Homo sapiens 53-60 14901235-0 1952 The silicone-tube coagulation time as an aid in the diagnosis of phlebothrombosis. Silicones 4-12 activation induced cytidine deaminase Homo sapiens 41-44 549504-0 1979 Effect of air nuclei on the adsorption of fibrinogen to silicone rubber. Silicones 56-64 fibrinogen beta chain Homo sapiens 42-52 636406-4 1978 It consists in diverting the CSF from the lateral ventricle of the brain into the internal jugular vein by means of ventricular silicone rubber catheter and a venous auto- or homograft. Silicones 128-136 colony stimulating factor 2 Homo sapiens 29-32 196405-1 1977 The nature of protamine splitting proteinase, which was formed after treatment of human blood plasma by kaolin or silicone (aerosile), was studied. Silicones 114-122 endogenous retrovirus group K member 18 Homo sapiens 34-44 951840-6 1976 Fibrinogen, albumin and IgG were readily identified when adsorbed from a single protein solution onto teflon or silicone rubber. Silicones 112-120 fibrinogen beta chain Homo sapiens 0-10 1092295-3 1975 This revascularization can ve prevented by placing silicone elastomers (Silastic) sheeting between the flap and its bed. Silicones 51-59 arachidonate 5-lipoxygenase activating protein Homo sapiens 103-107 46289-4 1975 More significant is the fact that since the silicone gel pillow has been enclosed in the marlex strap we have had 6 successes., 1 partial successs and no failures. Silicones 44-52 serine/threonine kinase receptor associated protein Homo sapiens 96-101 4373493-2 1974 The intrarenal gradient of renin activity was determined in rats by using superficial (S) and deep (D) cortical juxtaglomerular apparatuses (JGA"s), identified and microdissected after silicone-rubber compound injection. Silicones 185-193 renin Rattus norvegicus 27-32 4373493-4 1974 When, in rats on a normal NaCl diet, silicone-rubber was injected into a carotid artery, alone or with abdominal aorta catheterization, S:D renin activity ratios were 1.18+/-0.08 (SEM) and 1.21+/-0.12, respectively. Silicones 37-45 renin Rattus norvegicus 140-145 4373493-5 1974 The S:D renin activity ratios obtained when silicone-rubber was injected into the abdominal aorta (2.52+/-0.09) or a chronic carotid artery catheter (3.44+/-0.40) were significantly higher (P < 0.001). Silicones 44-52 renin Rattus norvegicus 8-13 5466188-2 1970 Clinical and pathological changes using silicone coated tip]. Silicones 40-48 TOR signaling pathway regulator Homo sapiens 56-59 5381864-0 1969 Thermoluminescent dosimeter of LiF incorporated in silicone rubber. Silicones 51-59 LIF interleukin 6 family cytokine Homo sapiens 31-34 5811225-0 1969 Intracorneal migration of a silicone strap. Silicones 28-36 serine/threonine kinase receptor associated protein Homo sapiens 37-42 5240721-0 1968 Use of silicone rubber membrane enclosures for preparation of erythropoietin assay mice. Silicones 7-15 erythropoietin Mus musculus 62-76 34031559-0 2021 Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-beta. Silicones 45-53 transforming growth factor alpha Mus musculus 119-127 34031559-2 2021 Here, we show that both softening of the implant surfaces and inhibition of the activation of TGF-beta1 reduce the fibrotic encapsulation of subcutaneous silicone implants in mice. Silicones 154-162 transforming growth factor, beta 1 Mus musculus 94-103 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 202-211 integrin alpha V Mus musculus 29-44 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 202-211 transforming growth factor alpha Mus musculus 108-116 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 202-211 centromere protein J Mus musculus 156-182 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 202-211 centromere protein J Mus musculus 184-187 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 225-234 integrin alpha V Mus musculus 29-44 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 225-234 centromere protein J Mus musculus 156-182 34031559-5 2021 In vitro, the recruitment of alphav integrin to focal adhesions and the activation of beta1 integrin and of TGF-beta were higher in myofibroblasts grown on latency-associated peptide (LAP)-coated stiff silicones than on soft silicones. Silicones 225-234 centromere protein J Mus musculus 184-187 33935489-2 2021 The purpose of this study was to evaluate the effects of two lens care systems on total protein and the quantity and activity of lysozyme deposited on worn senofilcon A, silicone hydrogel contact lenses. Silicones 170-178 lysozyme Homo sapiens 129-137 33493273-6 2021 We designed, built, and characterized quantitatively a benchtop flow-loop using a deformable AAA silicone phantom representative of a patient-specific geometry. Silicones 97-105 AAA1 Homo sapiens 93-96 33735370-6 2021 Numerous PEO-SA modified silicone formulations demonstrated effective water-driven surface hydrophilicity that was generally diminished with the addition of HMDS-treated silica filler. Silicones 25-33 twinkle mtDNA helicase Homo sapiens 9-12 33735370-7 2021 While increased yield stress was observed for PEO-SA modified silicones with added HMDS-treated filler, none achieved the initial target for 3D printing (>1000 Pa). Silicones 62-71 twinkle mtDNA helicase Homo sapiens 46-49 33735370-11 2021 Combined, these results demonstrate the potential of silicones modified with PEO-SA surface-modifying additives (SMAs) for extrusion-based, DIW 3D printing applications. Silicones 53-62 twinkle mtDNA helicase Homo sapiens 77-80 33856922-7 2021 This report describes a PALB2 mutation-positive woman with a strong family history of breast cancer who underwent prophylactic bilateral nipple-sparing mastectomy with textured silicone implant placement. Silicones 177-185 partner and localizer of BRCA2 Homo sapiens 24-29 33632049-15 2021 This is the first clinical trial on the application of Lady Care silicone gel sheet for the prevention of CS scarring. Silicones 66-74 citrate synthase Homo sapiens 107-109 33272095-5 2021 These observations provide further evidence that silicone lubricant in insulin syringes/needles is the source of clear spheres noted in the vitreous and foreign material noted near the injection track in the sclera. Silicones 49-57 insulin Macaca fascicularis 71-78 33456008-2 2021 In this study, the Sara-sara feel was evaluated for silicone powder, cellulose powder, hydrophobized sericite powder, and various mixes of these powders. Silicones 52-60 zinc finger FYVE-type containing 9 Homo sapiens 24-28 33748040-2 2021 Methods: We performed a non-inferiority in vitro study to assess the safety of transfusing RBCC for 4 h at a 4 ml/h speed through 24G silicone and 28G polyurethane PICC lines, compared with a peripheral 24G short catheter. Silicones 134-142 tripartite motif containing 17 Homo sapiens 91-95 33748040-10 2021 Conclusions: This study shows that RBCC transfusion performed in vitro through 24G silicone and 28G polyurethane PICC lines is feasible without detectable hemolysis or pressure concerns. Silicones 83-91 tripartite motif containing 17 Homo sapiens 35-39 32717110-0 2021 3D Printed Cutting Rig for Creating Silicone Carving Templates for Medialization Laryngoplasty. Silicones 36-44 dickkopf WNT signaling pathway inhibitor 3 Homo sapiens 19-22 33301901-8 2021 The SENS-IS assay was transferred to a naive laboratory which correctly identified sensitizers in six blinded silicone samples, including the one containing phenyl benzoate. Silicones 110-118 potassium channel tetramerization domain containing 1 Homo sapiens 4-8 32100081-5 2021 RESULTS: The absolute volume differences of T2-spc-Silicone group were significantly less than T2-spc-H2O and T2 group (6.28 vs. 23.27 vs. 42.19 mL, P < 0.05) in vitro. Silicones 51-59 proline rich protein gene cluster Homo sapiens 47-50 32100081-7 2021 Besides, the voxel size of T2-spc-Silicone from 0.5 x 0.5 x 0.5 mm to 5.0 x 5.0 x 5.0 mm did not significantly affect the accuracy of volume measurement of the implants in deformation state. Silicones 34-42 proline rich protein gene cluster Homo sapiens 30-33 32100081-11 2021 In normal patients, the measurement errors of T2-spc-Silicone were around 10 mL. Silicones 53-61 proline rich protein gene cluster Homo sapiens 49-52 32100081-13 2021 Moreover, implant deformations were clearly presented by T2-spc-Silicone with the voxel size of 1.0 x 1.0 x 1.0 mm. Silicones 64-72 proline rich protein gene cluster Homo sapiens 60-63 32100081-17 2021 T2-spc-Silicone with voxel size less than 2.0 x 2.0 x 2.0 mm could be used for 3D reconstruction of the implant deformation. Silicones 7-15 proline rich protein gene cluster Homo sapiens 3-6 33107637-4 2021 RESULTS: When CD44high OM-1 cells were cultured on 2.0-kPa laminin-coated silicone gel, the cells exhibited an amoeboid-like round morphology. Silicones 74-82 CD44 molecule (Indian blood group) Homo sapiens 14-18 33456008-3 2021 It was found that the highest Sara-sara feel score was achieved by the silicone powder. Silicones 71-79 zinc finger FYVE-type containing 9 Homo sapiens 30-34 33456008-3 2021 It was found that the highest Sara-sara feel score was achieved by the silicone powder. Silicones 71-79 zinc finger FYVE-type containing 9 Homo sapiens 35-39 33434030-3 2021 This study aimed to investigate the impact of the structure of the recombinant human PRG4 (rhPRG4)/HA complex on contact lens properties, when one agent is grafted and the counterpart is physisorbed on the surface of model conventional or silicone contact lens materials. Silicones 239-247 proteoglycan 4 Homo sapiens 85-89 33421336-0 2021 Silicone microbubbles after anti-vascular endothelial growth factor injections in patients with wet age-related macular degeneration: incidence, quantification and secondary optical coherence tomography artfacts. Silicones 0-8 vascular endothelial growth factor A Homo sapiens 33-67 33106319-7 2021 RESULTS: Silicone vessels maintained confluent, PECAM-1 (platelet endothelial cell adhesion molecule 1) positive endothelial cell linings over time. Silicones 9-17 platelet and endothelial cell adhesion molecule 1 Homo sapiens 48-55 33348602-3 2020 Stressing fibroblasts using ferromagnetic microbeads, stretchable silicone membranes, and cell contraction agonists all result in kindlin-2 translocation to the nucleus. Silicones 66-74 FERM domain containing kindlin 2 Homo sapiens 130-139 33217384-2 2020 Here, the use of fibronectin-functionalized silicone elastomers that exhibit considerable frequency-dependence in viscoelastic properties unveiled the presence of two cellular processes that respond discreetly to substrate mechanical properties. Silicones 44-52 fibronectin 1 Homo sapiens 17-28 32604541-2 2020 Vinyltrimethoxysilane (VTMS) and cobalt oxide nanoparticles are used as additives for the basic combination of silicone monomer (Sil-H) and methyl methacrylate (MMA). Silicones 111-119 STIL centriolar assembly protein Homo sapiens 129-132 33106319-7 2021 RESULTS: Silicone vessels maintained confluent, PECAM-1 (platelet endothelial cell adhesion molecule 1) positive endothelial cell linings over time. Silicones 9-17 platelet and endothelial cell adhesion molecule 1 Homo sapiens 57-102 32729495-4 2020 By monitoring the real time current change upon the addition of biotin solution in bovine serum albumin (BSA) in the silicone pool preformed onto the GFET, the lowest detectable biotin concentration is estimated to be 90 fg/ml (0.37 pM). Silicones 117-125 albumin Homo sapiens 90-103 31688670-1 2020 PURPOSE: To describe novel findings of hyperreflective material in the silicone-retina interphase on spectral domain optical coherence tomography (SD-OCT) imaging in eyes with silicone oil tamponade. Silicones 71-79 plexin A2 Homo sapiens 150-153 31688670-1 2020 PURPOSE: To describe novel findings of hyperreflective material in the silicone-retina interphase on spectral domain optical coherence tomography (SD-OCT) imaging in eyes with silicone oil tamponade. Silicones 176-184 plexin A2 Homo sapiens 150-153 32659841-0 2020 [Recanalisation by Probing with a Bicanalicular Silicone Tube (Oggel Silicone Intubation) in Patients with Acquired Lacrimal Stenosis]. Silicones 48-56 tubulin epsilon 1 Homo sapiens 57-61 33082755-7 2020 Her M-protein decreased from 2.14 to 0.83 g/dL and her IgG levels from 3,330 to 1,210 mg/dL following replacement of her silicone implant with saline. Silicones 121-129 myomesin 2 Homo sapiens 4-13 32659841-0 2020 [Recanalisation by Probing with a Bicanalicular Silicone Tube (Oggel Silicone Intubation) in Patients with Acquired Lacrimal Stenosis]. Silicones 69-77 tubulin epsilon 1 Homo sapiens 57-61 32659841-1 2020 OBJECTIVES: Recanalisation and bicanalicular splinting with silicone tube is one therapeutic option for acquired lacrimal duct stenosis, and restenosis is frequently achieved. Silicones 60-68 tubulin epsilon 1 Homo sapiens 69-73 32659841-16 2020 The therapeutic success of bicanalicular silicone intubation with the Oggel tube was in the lower third of comparable studies. Silicones 41-49 tubulin epsilon 1 Homo sapiens 76-80 32717789-1 2020 Silicone and pure organic binders were used to develop FAU-type zeolite coatings applied on pre-treated aluminum substrates by using a spraying method and then cured under specific conditions. Silicones 0-8 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 55-58 32434081-4 2020 Based on instruction of the failed case, we designed an advanced EPC-capture stent covered with anti-CD146 antibody (Ab) immobilized silicone nanofilament (SiNf) for the highly efficient and specific capture of not early but late stage of EPCs. Silicones 133-141 melanoma cell adhesion molecule Homo sapiens 101-106 32464050-4 2020 In this study, we establish covalent surface coatings with mucin macromolecules to overcome this issue for pure silicone contact lenses. Silicones 112-120 LOC100508689 Homo sapiens 59-64 30642195-12 2020 Silicone-free insulin syringes with staked-in needles would be strongly recommended for supplying anti-vascular endothelial growth factor intravitreal injections from compounding pharmacies. Silicones 0-8 vascular endothelial growth factor A Homo sapiens 103-137 32382034-5 2020 The close work function match between silicone and silver enables electron tunneling between nanosatellite particles, increasing electrical conductivity by ~5 orders of magnitude (1.02x103 Scm-1) without coalescence of fillers. Silicones 38-46 X-C motif chemokine ligand 1 Homo sapiens 189-194 32530782-6 2020 Additionally, the health professionals rated the handling of exudate as excellent/good (78%) and most (80%) reported that they would use the SAP silicone border dressing again. Silicones 145-153 SH2 domain containing 1A Homo sapiens 141-144 32530782-7 2020 Allied to this was the fact that the SAP silicone border dressing improved the wound edge and periwound skin conditions (29% and 36% of patients, respectively). Silicones 41-49 SH2 domain containing 1A Homo sapiens 37-40 32530782-8 2020 Regarding dressing retention, the SAP silicone border dressing retained its position in 72% of patients. Silicones 38-46 SH2 domain containing 1A Homo sapiens 34-37 32530782-11 2020 CONCLUSION: The SAP silicone border dressing was successful in managing wound exudate in moderately to highly exuding wounds and consequently this had a beneficial impact on the wound edge and periwound skin. Silicones 20-28 SH2 domain containing 1A Homo sapiens 16-19 32530782-13 2020 This study has shown that the SAP silicone border dressing successfully controlled exudate and provided positive benefits when used in the treatment of patients with moderately to highly exuding wounds. Silicones 34-42 SH2 domain containing 1A Homo sapiens 30-33 32422917-7 2020 Hydrophobicity of the PET support layer was further tuned by adding a spin-coated silicone layer to it. Silicones 82-90 spindlin 1 Homo sapiens 70-74 32511736-1 2020 The authors present a case of diffuse silicone oil deposits from intravitreal anti-vascular endothelial growth factor injections adhering to the posterior capsule of a silicone intraocular lens. Silicones 38-46 vascular endothelial growth factor A Homo sapiens 83-117 32207652-9 2020 Trio Healthcare has introduced this technology with a range of silicone-based flange extenders and is working with the University of Bradford Centre for Skin Sciences on prototype silicone-based stoma appliance flanges designed to significantly reduce the incidence of peristomal skin complications, such as MARSI and MASD. Silicones 63-71 trio Rho guanine nucleotide exchange factor Homo sapiens 0-4 32450498-9 2020 We further constructed a CD47 surface immobilized silicone tubing filled with NO releasing S-nitrosoglutathione/ascorbic acid (GSNO/AA) solution for synergistic biocompatibility evaluation. Silicones 50-58 CD47 molecule Homo sapiens 25-29 33455354-5 2020 Under static conditions, silicones modified with either SMA at concentrations of 10 mumol/g or greater were effective in reducing adhesion of human fibrinogen and platelets. Silicones 25-34 survival of motor neuron 1, telomeric Homo sapiens 56-59 33455354-5 2020 Under static conditions, silicones modified with either SMA at concentrations of 10 mumol/g or greater were effective in reducing adhesion of human fibrinogen and platelets. Silicones 25-34 fibrinogen beta chain Homo sapiens 148-158 32296013-0 2020 A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway. Silicones 8-16 Janus kinase 2 Homo sapiens 138-142 32296013-0 2020 A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway. Silicones 8-16 signal transducer and activator of transcription 3 Homo sapiens 143-148 32207652-9 2020 Trio Healthcare has introduced this technology with a range of silicone-based flange extenders and is working with the University of Bradford Centre for Skin Sciences on prototype silicone-based stoma appliance flanges designed to significantly reduce the incidence of peristomal skin complications, such as MARSI and MASD. Silicones 180-188 trio Rho guanine nucleotide exchange factor Homo sapiens 0-4 32033137-0 2020 Electrical Strength and Physicochemical Performances of HTV Silicone Rubber under Salt-Fog Environment with DC Energized. Silicones 60-68 zinc finger protein, FOG family member 1 Homo sapiens 87-90 32033137-2 2020 In this paper, salt-fog experiments with DC test voltage of high-temperature vulcanized (HTV) silicone rubber (SR) have been conducted. Silicones 94-102 zinc finger protein, FOG family member 1 Homo sapiens 20-23 31707084-8 2020 Lastly, this 94%PCL-06%PGMA stent exhibited more standout critical functions in a series of in vitro and in vivo experiments such as a cell growth-supporting level of biocompatibility with nasal epithelial cells without significant inflammatory responses, better resistance to biofilm formation, and more efficient capacity to drain tear than the silicone control. Silicones 347-355 PHD finger protein 1 Homo sapiens 16-19 31941700-5 2020 We observed that C3H10T1/2 cells cultured in 2D conditions on silicone substrate were more prone to tendon differentiation assessed with the expression of the tendon markers Scx, Col1a1 and Tnmd as compared to cells cultured on plastic substrate. Silicones 62-70 scleraxis Mus musculus 174-177 31941700-5 2020 We observed that C3H10T1/2 cells cultured in 2D conditions on silicone substrate were more prone to tendon differentiation assessed with the expression of the tendon markers Scx, Col1a1 and Tnmd as compared to cells cultured on plastic substrate. Silicones 62-70 collagen, type I, alpha 1 Mus musculus 179-185 31941700-5 2020 We observed that C3H10T1/2 cells cultured in 2D conditions on silicone substrate were more prone to tendon differentiation assessed with the expression of the tendon markers Scx, Col1a1 and Tnmd as compared to cells cultured on plastic substrate. Silicones 62-70 tenomodulin Mus musculus 190-194 32095072-0 2020 VEGF-Modified PVA/Silicone Nanofibers Enhance Islet Function Transplanted in Subcutaneous Site Followed by Device-Less Procedure. Silicones 18-26 vascular endothelial growth factor A Homo sapiens 0-4 31845798-8 2020 Furthermore, the mPep-coated silicone catheter induces no inflammatory response and significantly lowers the bacterial cell number with 6 log reduction in a mouse model of infection. Silicones 29-37 prolyl endopeptidase Mus musculus 17-21 31594478-1 2020 The aim of this study was to determine the sorption location of full-length recombinant human proteoglycan 4 (rhPRG4) tagged with fluorescein isothiocyanate (FITC) to four silicone hydrogel contact lenses [balafilcon A (PureVision, Bausch + Lomb), senofilcon A (Acuvue Oasys, Johnson & Johnson), comfilcon A (Biofinity, CooperVision), lotrafilcon B (Air Optix, Alcon)] and one conventional hydrogel lens [etafilcon A (Acuvue 2, Johnson & Johnson)], using confocal laser scanning microscopy (CLSM). Silicones 172-180 proteoglycan 4 Homo sapiens 94-108 31817825-0 2019 Silicone Rubber Composites with High Breakdown Strength and Low Dielectric Loss Based on Polydopamine Coated Mica. Silicones 0-8 MHC class I polypeptide-related sequence A Homo sapiens 109-113 31342127-0 2019 Smooth Prosthesis: Our Experience and Current State of Art in the Use of Smooth Sub-muscular Silicone Gel Breast Implants. Silicones 93-101 artemin Homo sapiens 55-58 31569481-3 2019 The design of the SNTN employs flexible silicone rubber as the negative friction material and Ni-coated polyester conductive textile as the positive friction material and the electrode material. Silicones 40-48 sentan, cilia apical structure protein Homo sapiens 18-22 32036367-12 2020 Foveal GCL, OPL and ONL, perifoveal GCL and IPL were statistically thinner in the silicone tamponade group (p=0.01, p=0.046, p=0.024, p=0.006, p=0.011 respectively). Silicones 82-90 germ cell-less 2, spermatogenesis associated Homo sapiens 36-39 31754373-2 2019 The present study provides in vivo trials of silicone rubber chambers filled with collagen containing IFN-gamma or IL-4 to bridge a 15 mm sciatic nerve defect in rats. Silicones 45-53 interferon gamma Rattus norvegicus 102-111 31694187-0 2019 Silicone Resin Polymer Used in Preventive Maintenance of Asphalt Mixture Based on Fog Seal. Silicones 0-14 zinc finger protein, FOG family member 1 Homo sapiens 82-85 31694187-3 2019 Therefore, silicone resin polymer was used as a kind of innovative fog seal material in this study. Silicones 11-19 zinc finger protein, FOG family member 1 Homo sapiens 67-70 31573113-4 2019 The most known polymers used in plastination are silicone (S10), epoxy (E12) and polyester (P40). Silicones 49-57 ribosomal protein S10 Homo sapiens 59-62 31573113-6 2019 The S10 silicone technique is the most common technique used in plastination. Silicones 8-16 ribosomal protein S10 Homo sapiens 4-7 30877446-5 2019 The LDM flap was transposed to the front to reconstruct the breast with a silicone implant. Silicones 74-82 arachidonate 5-lipoxygenase activating protein Homo sapiens 8-12 31220446-13 2019 CONCLUSIONS: SEMSs covered with a silicone membrane containing integrated Ag-Ps may be effective and safe in malignant distal biliary obstruction. Silicones 34-42 alkylglycerone phosphate synthase Homo sapiens 74-79 31026955-5 2019 Theh Guth and Gold equation showed mechanical reinforcement of porous silicone/HSP composites was primarily due to the hydrodynamic effect of HSPs in the silicone matrix at low HSP contents (Phi < 0.5). Silicones 70-78 heat shock protein 90 beta family member 2, pseudogene Homo sapiens 142-145 31026955-5 2019 Theh Guth and Gold equation showed mechanical reinforcement of porous silicone/HSP composites was primarily due to the hydrodynamic effect of HSPs in the silicone matrix at low HSP contents (Phi < 0.5). Silicones 154-162 heat shock protein 90 beta family member 2, pseudogene Homo sapiens 79-82 31026955-5 2019 Theh Guth and Gold equation showed mechanical reinforcement of porous silicone/HSP composites was primarily due to the hydrodynamic effect of HSPs in the silicone matrix at low HSP contents (Phi < 0.5). Silicones 154-162 heat shock protein 90 beta family member 2, pseudogene Homo sapiens 142-145 30972705-4 2019 It was also found that silicone rubber membrane can control NO2--N and/or NO3--N production. Silicones 23-31 NBL1, DAN family BMP antagonist Homo sapiens 74-77 31323952-3 2019 METHODS: Bite marks were analyzed on five materials: rubber, plastic, foil, wood, and silicone. Silicones 86-94 centrosomal protein 70 Homo sapiens 9-13 31089062-8 2019 CD4 immunoreactivity was obviously weaker in rats subjected to repair with electrospun absorbable biopolymer nanofiber conduits than in those subjected to repair with poly(epsilon-caprolactone) or silicone. Silicones 197-205 Cd4 molecule Rattus norvegicus 0-3 30395878-1 2019 AIM: To compare the effect of conventional wound dressings (CD) with vitamin E and silicone (E-Sil) dressings on incisional surgical site infection (SSI) in patients undergoing elective colorectal laparoscopic surgery. Silicones 83-91 STIL centriolar assembly protein Homo sapiens 95-98 30593660-5 2019 While the hemoglobin alone failed to maintain alginate macroencapsulated neonate pig islets under hypoxia, silicone-CaO2 alone or combined to the hemoglobin restored islet viability and insulin secretion and prevented proinflammatory metabolism (PTGS2 expression). Silicones 107-115 insulin Sus scrofa 186-193 31181677-1 2019 A 193-nm ArF excimer laser was used to induce the photodissociation of Si-O bonds of silicone rubber in order to fabricate a periodic micro/nano-suction cup silicone structure, approximately 1 mum in diameter and 2 mum in height at regular intervals of 2.5 mum. Silicones 85-93 latexin Homo sapiens 193-196 31181677-1 2019 A 193-nm ArF excimer laser was used to induce the photodissociation of Si-O bonds of silicone rubber in order to fabricate a periodic micro/nano-suction cup silicone structure, approximately 1 mum in diameter and 2 mum in height at regular intervals of 2.5 mum. Silicones 85-93 latexin Homo sapiens 215-218 31181677-1 2019 A 193-nm ArF excimer laser was used to induce the photodissociation of Si-O bonds of silicone rubber in order to fabricate a periodic micro/nano-suction cup silicone structure, approximately 1 mum in diameter and 2 mum in height at regular intervals of 2.5 mum. Silicones 85-93 latexin Homo sapiens 215-218 31181677-2 2019 The laser was focused on Al-coated silicone rubber by each silica glass microsphere 2.5 mum in diameter, which covered the entire surface of the silicone rubber. Silicones 35-43 latexin Homo sapiens 88-91 30593660-5 2019 While the hemoglobin alone failed to maintain alginate macroencapsulated neonate pig islets under hypoxia, silicone-CaO2 alone or combined to the hemoglobin restored islet viability and insulin secretion and prevented proinflammatory metabolism (PTGS2 expression). Silicones 107-115 prostaglandin-endoperoxide synthase 2 Sus scrofa 246-251 30513058-7 2019 Postoperative elevation of either aspartate transaminase (AST) or alanine aminotransferase (ALT) level was recognized in 13 (72.2%) of the Silicone group patients and 18 (100%) of the Penrose group patients (P = .0160). Silicones 139-147 solute carrier family 17 member 5 Homo sapiens 34-56 30513058-7 2019 Postoperative elevation of either aspartate transaminase (AST) or alanine aminotransferase (ALT) level was recognized in 13 (72.2%) of the Silicone group patients and 18 (100%) of the Penrose group patients (P = .0160). Silicones 139-147 solute carrier family 17 member 5 Homo sapiens 58-61 30513058-7 2019 Postoperative elevation of either aspartate transaminase (AST) or alanine aminotransferase (ALT) level was recognized in 13 (72.2%) of the Silicone group patients and 18 (100%) of the Penrose group patients (P = .0160). Silicones 139-147 glutamic--pyruvic transaminase Homo sapiens 66-90 30513058-8 2019 The mean AST and ALT levels in the Silicone group were significantly lower than those in the Penrose group on postoperative days 0, 1, and 3. Silicones 35-43 solute carrier family 17 member 5 Homo sapiens 9-12 29604311-8 2018 To show that the silicone particles can elicit a favorable biological response, similar to the Microsponge particles, we applied both formulations to reconstructed human epidermal tissues and found an upregulation of keratin 19 (K19) and a downregulation of K10, indicating that the reduced irritation observed in the human study was not caused by reduced activity. Silicones 17-25 keratin 19 Homo sapiens 218-228 30276460-0 2019 Smooth Muscle Alpha Actin Immunoexpression (alpha-Sma) and CD-117 Antibody (C-Kit) in Capsules Formed by Polyurethane Foam-Coated Silicone Implants and with Textured Surface: A Study on Rats. Silicones 130-138 actin alpha 2, smooth muscle Rattus norvegicus 0-25 32672670-4 2019 METHODS: Using an ab interno approach, 25 eyes were implanted successfully in a stand-alone procedure with a 5-mm long device made of biocompatible STAR material, which is soft and flexible silicone in a microporous, network design. Silicones 190-198 steroidogenic acute regulatory protein Homo sapiens 148-152 30428981-6 2018 In addition, the presence of a PFOS structural isomer was found at 29.0 ng mL-1: this compound was released in part from the infusion tubes and mostly from the venous catheters, particularly from silicone ones. Silicones 196-204 L1 cell adhesion molecule Mus musculus 75-79 30533339-3 2018 Here, we report an unusual case of implant-associated SCC of the breast post silicone gel breast implant. Silicones 77-85 serpin family B member 3 Homo sapiens 54-57 29636243-0 2018 Surface morphology of silicone soft relining material after mechanical and chemical cleaning. Silicones 22-30 POC1 centriolar protein A Homo sapiens 31-35 29636243-1 2018 PURPOSE: The objective was to investigate the influence of chemical and mechanical cleaning on the surface morphology of a silicone soft relining material. Silicones 123-131 POC1 centriolar protein A Homo sapiens 132-136 30114356-5 2018 Full-length recombinant human PRG4 (rhPRG4) was successfully grafted onto the surface of model conventional and silicone hydrogel (SiHy) contact lenses via its somatomedin B-like end-domain using N, N"-carbonyldiimidazole linking chemistry. Silicones 112-120 proteoglycan 4 Homo sapiens 30-34 30960934-3 2018 Then, ultraviolet (UV) light-induced graft polymerization of N-isopropylacrylamide (NIPAAm) and acrylic acid (AAc) in different molar ratios were applied onto the organic silicone film in order to immobilize thermos-/pH-sensitive composite hydrogels on the surface. Silicones 171-179 glycine-N-acyltransferase Homo sapiens 110-113 29942863-7 2018 The outer shell made of silicone elastomer protects the CLC core and the inner shell from the surroundings. Silicones 24-32 Charcot-Leyden crystal galectin Homo sapiens 56-59 29604311-8 2018 To show that the silicone particles can elicit a favorable biological response, similar to the Microsponge particles, we applied both formulations to reconstructed human epidermal tissues and found an upregulation of keratin 19 (K19) and a downregulation of K10, indicating that the reduced irritation observed in the human study was not caused by reduced activity. Silicones 17-25 keratin 19 Homo sapiens 230-233 29868624-3 2018 In order to complete re-implantation the defect was closed using a rotation flap constructed from capsular tissue from the previous silicone implant. Silicones 132-140 arachidonate 5-lipoxygenase activating protein Homo sapiens 76-80 29735949-1 2018 Moisture-resistant silicone coatings were prepared on the surface of potassium dihydrogen phosphate (KDP) crystal by means of spin-coating, in which hydrophobic-modified SiO2 nanoparticles were embedded in a certain proportion. Silicones 19-27 WNK lysine deficient protein kinase 1 Homo sapiens 101-104 29604311-8 2018 To show that the silicone particles can elicit a favorable biological response, similar to the Microsponge particles, we applied both formulations to reconstructed human epidermal tissues and found an upregulation of keratin 19 (K19) and a downregulation of K10, indicating that the reduced irritation observed in the human study was not caused by reduced activity. Silicones 17-25 keratin 10 Homo sapiens 259-262 29854742-0 2018 The Role of Periostin in Capsule Formation on Silicone Implants. Silicones 46-54 periostin, osteoblast specific factor Mus musculus 12-21 29854742-11 2018 Inhibition of periostin could be important for suppressing capsule formation on silicone implants after in vivo implantation. Silicones 80-88 periostin, osteoblast specific factor Mus musculus 14-23 29904650-5 2018 Furthermore, the effect of blending ratio of two parts of silicone binder on its curing speed was investigated by conducting DSC tests on a silicone binder with 100:2 precursor to curing agent ratio. Silicones 58-66 desmocollin 3 Homo sapiens 125-128 28688149-8 2018 PRG4 effectively lubricated both silicone hydrogel materials and HA effectively lubricated pHEMA/TRIS, as indicated by a statistically significant reduction in friction compared to the saline control lubricant. Silicones 33-41 proteoglycan 4 Bos taurus 0-4 28688149-10 2018 Biological boundary lubricants HA and PRG4 were shown to effectively lubricate silicone hydrogels when in solution. Silicones 79-87 proteoglycan 4 Bos taurus 38-42 29381345-7 2018 In particular, we found that the silicone oils deposited from the AFM tip into the scanned regions and spread to distances exceeding 15 mum from the tip. Silicones 33-41 TOR signaling pathway regulator Homo sapiens 70-73 29381345-7 2018 In particular, we found that the silicone oils deposited from the AFM tip into the scanned regions and spread to distances exceeding 15 mum from the tip. Silicones 33-41 TOR signaling pathway regulator Homo sapiens 149-152 29495462-10 2018 For development of a new glaucoma drainage device, the silicones Silbione LSR 4330 and Silbione LSR 4350, in this study, with low cell counts for hTF and low proliferation indices for hSF, and silicone Silastic MDX4-4210, with low cell counts for hSF and low proliferation indices for hTF, have shown the best results in vitro. Silicones 55-63 interleukin 6 Homo sapiens 184-187 29238828-9 2018 This approach was applied to a silicone phantom model of an AAA reconstructed from a patient"s computed tomography-scan examination. Silicones 31-39 AAA1 Homo sapiens 60-63 28438322-6 2017 Movement artefacts were more frequent in set 1 whereas five cases (18.5%) exhibited swap artefacts between silicone and water in set 2. Silicones 107-115 SET domain containing 2, histone lysine methyltransferase Homo sapiens 129-134 29245939-0 2017 Identification of hub genes related to silicone-induced immune response in rats. Silicones 39-47 ELAV like RNA binding protein 2 Rattus norvegicus 18-21 29245939-4 2017 The objective of the present study was to determine the hub genes and key pathways related to silicone implant-induced immune responses in a rat model. Silicones 94-102 ELAV like RNA binding protein 2 Rattus norvegicus 56-59 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 allograft inflammatory factor 1 Rattus norvegicus 25-29 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 GATA binding protein 3 Rattus norvegicus 31-36 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 toll-like receptor 6 Rattus norvegicus 38-42 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 toll-like receptor 2 Rattus norvegicus 44-48 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 ELAV like RNA binding protein 2 Rattus norvegicus 69-72 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 allograft inflammatory factor 1 Rattus norvegicus 164-168 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 GATA binding protein 3 Rattus norvegicus 170-175 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 toll-like receptor 6 Rattus norvegicus 177-181 29245939-6 2017 A total five genes (Fes, Aif1, Gata3, Tlr6, Tlr2) were identified as hub genes that are most likely related to the silicone-induced immune response, four of which (Aif1, Gata3, Tlr6, Tlr2) have been associated with autoimmunity as target genes or disease markers. Silicones 115-123 toll-like receptor 2 Rattus norvegicus 183-187 29245939-9 2017 The identified five hub genes will hopefully serve as novel therapeutic targets for silicone-related complications and the associated autoimmune diseases. Silicones 84-92 ELAV like RNA binding protein 2 Rattus norvegicus 20-23 28796097-11 2017 RESULTS: Tip proportions (angle of convexity of the face with nose, nose tip-length quotient, tip projection anterior glabellar line quotient) improved in silicone group, but cartilage group achieved superior esthetic outcomes than silicone in tip projection, subnasal protrusion, and nasal labial angle. Silicones 155-163 TOR signaling pathway regulator Homo sapiens 9-12 28796097-11 2017 RESULTS: Tip proportions (angle of convexity of the face with nose, nose tip-length quotient, tip projection anterior glabellar line quotient) improved in silicone group, but cartilage group achieved superior esthetic outcomes than silicone in tip projection, subnasal protrusion, and nasal labial angle. Silicones 155-163 TOR signaling pathway regulator Homo sapiens 73-76 28796097-11 2017 RESULTS: Tip proportions (angle of convexity of the face with nose, nose tip-length quotient, tip projection anterior glabellar line quotient) improved in silicone group, but cartilage group achieved superior esthetic outcomes than silicone in tip projection, subnasal protrusion, and nasal labial angle. Silicones 155-163 TOR signaling pathway regulator Homo sapiens 94-97 28796097-11 2017 RESULTS: Tip proportions (angle of convexity of the face with nose, nose tip-length quotient, tip projection anterior glabellar line quotient) improved in silicone group, but cartilage group achieved superior esthetic outcomes than silicone in tip projection, subnasal protrusion, and nasal labial angle. Silicones 155-163 TOR signaling pathway regulator Homo sapiens 94-97 28773020-2 2017 [(TPTA)2Ir(dPPOA)]PF6 has high thermal stability with a decomposition temperature (Td) of 375 C, and its relative emission intensity at 100 C is 88.8% of that at 25 C. When only [(TPTA)2Ir(dPPOA)]PF6 was used as a phosphor at 6.0 wt % in silicone and excited by a blue GaN (GaN: gallium nitride) chip (450 nm), an orange LED was obtained. Silicones 240-248 sperm associated antigen 17 Homo sapiens 18-21 28531997-0 2017 Sustained release of growth hormone and sodium nitrite from biomimetic collagen coating immobilized on silicone tubes improves endothelialization. Silicones 103-111 growth hormone 1 Homo sapiens 21-35 28531997-3 2017 We aimed to test whether incorporation of growth-inducing nanoliposomal growth hormone (nGH) and anti-thrombotic nanoliposomal sodium nitrite (nNitrite) into collagen coating of silicone tubes enhances endothelialization by stimulating endothelial cell proliferation and inhibiting platelet adhesion. Silicones 178-186 growth hormone 1 Homo sapiens 72-86 28367509-0 2017 The stability of insulin solutions in syringes is improved by ensuring lower molecular weight silicone lubricants are absent. Silicones 94-102 insulin Homo sapiens 17-24 27842452-0 2017 Role of bolA and rpoS genes in biofilm formation and adherence pattern by Escherichia coli K-12 MG1655 on polypropylene, stainless steel, and silicone surfaces. Silicones 142-150 DNA-binding transcriptional dual regulator BolA Escherichia coli str. K-12 substr. MG1655 8-12 27842452-0 2017 Role of bolA and rpoS genes in biofilm formation and adherence pattern by Escherichia coli K-12 MG1655 on polypropylene, stainless steel, and silicone surfaces. Silicones 142-150 RNA polymerase sigma factor RpoS Escherichia coli str. K-12 substr. MG1655 17-21 27844255-7 2017 The clip consists of a silicone-covered titanium backbone with an inferior hinged opening that separates a medial lumen from an excluded lateral gastric pouch. Silicones 23-31 CAP-Gly domain containing linker protein 1 Homo sapiens 4-8 27543073-1 2017 Here we describe the long-term outcomes of type I thyroplasty (TP-I) with silicone block implantation through histopathological assessments in a male patient who underwent pharyngolaryngectomy for secondary hypopharyngeal carcinoma 7 years after silicone implantation. Silicones 74-82 triosephosphate isomerase 1 Homo sapiens 43-67 27543073-1 2017 Here we describe the long-term outcomes of type I thyroplasty (TP-I) with silicone block implantation through histopathological assessments in a male patient who underwent pharyngolaryngectomy for secondary hypopharyngeal carcinoma 7 years after silicone implantation. Silicones 246-254 triosephosphate isomerase 1 Homo sapiens 43-67 27798620-2 2017 Here, we show that priming on physiologically soft silicone substrates suppresses fibrogenesis and desensitizes mesenchymal stem cells (MSCs) against subsequent mechanical activation in vitro and in vivo, and identify the microRNA miR-21 as a long-term memory keeper of the fibrogenic program in MSCs. Silicones 51-59 microRNA 21 Homo sapiens 231-237 28264569-2 2017 The sensing materials are based on fluorescent BF2-chelated tetraarylazadipyrromethene dyes (aza-BODIPYs) dyes physically entrapped in polyurethane hydrogels and dispersed in silicone rubber. Silicones 175-183 forkhead box G1 Homo sapiens 47-50 27328334-2 2016 The primary aim of this study was to investigate whether the use of a silicone catheter coated with an ultrathin layer of a combination of the noble metals gold, palladium and silver (BIP -silicone catheter) could reduce the incidence of CAUTI and antibiotic prescription compared with a standard silicone catheter in a cohort of acute neurological patients suffering primarily from stroke. Silicones 70-78 heat shock protein family A (Hsp70) member 5 Homo sapiens 184-187 27328334-2 2016 The primary aim of this study was to investigate whether the use of a silicone catheter coated with an ultrathin layer of a combination of the noble metals gold, palladium and silver (BIP -silicone catheter) could reduce the incidence of CAUTI and antibiotic prescription compared with a standard silicone catheter in a cohort of acute neurological patients suffering primarily from stroke. Silicones 189-197 heat shock protein family A (Hsp70) member 5 Homo sapiens 184-187 27328334-2 2016 The primary aim of this study was to investigate whether the use of a silicone catheter coated with an ultrathin layer of a combination of the noble metals gold, palladium and silver (BIP -silicone catheter) could reduce the incidence of CAUTI and antibiotic prescription compared with a standard silicone catheter in a cohort of acute neurological patients suffering primarily from stroke. Silicones 189-197 heat shock protein family A (Hsp70) member 5 Homo sapiens 184-187 27391832-0 2016 Effect of Botulinum Toxin Type A on TGF-beta/Smad Pathway Signaling: Implications for Silicone-Induced Capsule Formation. Silicones 86-94 transforming growth factor beta 1 Homo sapiens 36-44 27391832-8 2016 In vivo, the effect of botulinum toxin type A on the phosphorylation of Smad2 in silicone-induced capsule formation was evaluated by immunocytochemistry. Silicones 81-89 SMAD family member 2 Homo sapiens 72-77 27391832-12 2016 In vivo, botulinum toxin type A treatment reduced capsule thickness and Smad2 phosphorylation in silicone-induced capsules. Silicones 97-105 SMAD family member 2 Homo sapiens 72-77 27341317-6 2016 Average number of CD68+ cells was higher (P<0.001) for MIRAgel than for silicone rubber. Silicones 75-83 CD68 molecule Homo sapiens 18-22 27389945-2 2016 We studied the partitioning of PCB congeners between indoor air and silicone with a view to establish passive sampling of PCBs. Silicones 68-76 pyruvate carboxylase Homo sapiens 31-34 27389945-3 2016 The release of PCB congeners from silicone followed first order kinetics and confirmed air-side rate-limited mass transfer. Silicones 34-42 pyruvate carboxylase Homo sapiens 15-18 27782732-10 2016 Signal uniformity for flex-RLI improved after more aggressive homogenization of the GOS powder with the silicone elastomer during formulation. Silicones 104-112 ATP-binding cassette, sub-family E (OABP), member 1 Mus musculus 27-30 27155193-0 2016 A Preliminary Assessment of the Predictability of Fat Grafting to Correct Silicone Breast Implant-Related Complications. Silicones 74-82 FAT atypical cadherin 1 Homo sapiens 50-53 27358554-4 2016 An automated fixture applied a 30 g load to simulate compression against the incision site, leading to friction between the silicone sleeve and the titanium tip. Silicones 124-132 TOR signaling pathway regulator Homo sapiens 157-160 27535925-0 2016 Commentary on: A Preliminary Assessment of the Predictability of Fat Grafting to Correct Silicone Breast Implant-Related Complications. Silicones 89-97 FAT atypical cadherin 1 Homo sapiens 65-68 27297564-3 2016 Remarkable resistance to bovine serum albumin and lysozyme fouling was observed for the silicone hydrogels immobilized with neutrally charged amino acids because of the formation of zwitterionic surfaces with pairs of protonated secondary ammonium cations and deprotonated carboxyl anions. Silicones 88-96 albumin Oryctolagus cuniculus 32-45 27579341-1 2016 The data presented in this article are related to the research article entitled "Smart photo-induced silicone/TiO2 nanocomposites with dominant [110] exposed surfaces for self-cleaning foul-release coatings of ship hulls" (Selimet al., 2016) [1]. Silicones 101-109 inositol polyphosphate-5-phosphatase D Homo sapiens 210-214 26687822-2 2016 DESIGN: An in vitro system for CTS studies was established using AF cultures on fibronectin-coated silicone dishes. Silicones 99-107 fibronectin 1 Homo sapiens 80-91 26975013-0 2016 Silicone Granuloma in the Buttocks Incidentally Detected by 18F-FDG PET/CT 30 Years After Free Liquid Silicone Injections. Silicones 0-8 transcription factor Dp family member 3 Homo sapiens 72-77 27018697-10 2016 Immunohistochemical staining results for CD4, tumor necrosis factor-alpha, alpha-smooth muscle actin, and elastin showed the possible mechanism enhancing the biocompatibility of silicone rubber. Silicones 178-186 Cd4 molecule Rattus norvegicus 41-73 27018697-10 2016 Immunohistochemical staining results for CD4, tumor necrosis factor-alpha, alpha-smooth muscle actin, and elastin showed the possible mechanism enhancing the biocompatibility of silicone rubber. Silicones 178-186 actin gamma 2, smooth muscle Rattus norvegicus 75-100 27018697-10 2016 Immunohistochemical staining results for CD4, tumor necrosis factor-alpha, alpha-smooth muscle actin, and elastin showed the possible mechanism enhancing the biocompatibility of silicone rubber. Silicones 178-186 elastin Rattus norvegicus 106-113 26697808-3 2016 Initially, silicone cord sorption efficacy was determined by assessing sorption kinetics using PAH-spiked sand (phenanthrene, pyrene and benzo[a]pyrene; 10-1000mgkg(-1)). Silicones 11-19 phenylalanine hydroxylase Homo sapiens 95-98 26973010-5 2016 This article explores the "Trio" range of silicone-based accessories, discussing how these products compare with the traditional hydrocolloid, how they are applied and used. Silicones 42-50 trio Rho guanine nucleotide exchange factor Homo sapiens 27-31 26697808-4 2016 Irrespective of PAH and concentration, >95% of the initial PAH mass partitioned into the silicone cord within 12h although rates were lower at higher concentration and with increasing hydrophobicity. Silicones 92-100 phenylalanine hydroxylase Homo sapiens 62-65 24602064-12 2016 This study confirms that BoNT-A prevents capsular formation around silicone implants, possibly by blocking TGF-beta1 signalling and interrupting the differentiation of fibroblasts to myofibroblasts. Silicones 67-75 transforming growth factor beta 1 Homo sapiens 107-116 26789595-0 2016 Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1beta and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model. Silicones 154-162 interleukin 1 beta Mus musculus 115-123 26789595-6 2016 Our findings evidenced the ability of such inhibitors to reduce host inflammation in silicone implants promoting a thickness reduction of peri-implant fibrous capsule, upregulating IL-10 expression, and reducing the production of both IL-1beta and IL-6. Silicones 85-93 interleukin 10 Mus musculus 181-186 26789595-6 2016 Our findings evidenced the ability of such inhibitors to reduce host inflammation in silicone implants promoting a thickness reduction of peri-implant fibrous capsule, upregulating IL-10 expression, and reducing the production of both IL-1beta and IL-6. Silicones 85-93 interleukin 1 beta Mus musculus 235-243 26789595-6 2016 Our findings evidenced the ability of such inhibitors to reduce host inflammation in silicone implants promoting a thickness reduction of peri-implant fibrous capsule, upregulating IL-10 expression, and reducing the production of both IL-1beta and IL-6. Silicones 85-93 interleukin 6 Mus musculus 248-252 26894011-3 2015 The authors describe, herein, a primary SCC arising from the capsule of a long-standing silicone breast implant. Silicones 88-96 serpin family B member 3 Homo sapiens 40-43 25923417-2 2016 The objective of the present study was to characterize a silicone pressure sensitive adhesive (PSA) episcleral implant system for transscleral drug delivery. Silicones 57-65 aminopeptidase puromycin sensitive Homo sapiens 95-98 25923417-3 2016 Silicone PSA implants for dexamethasone, atenolol, and bovine serum albumin (BSA) were prepared at different polymer-to-drug mass ratios. Silicones 0-8 aminopeptidase puromycin sensitive Homo sapiens 9-12 25923417-3 2016 Silicone PSA implants for dexamethasone, atenolol, and bovine serum albumin (BSA) were prepared at different polymer-to-drug mass ratios. Silicones 0-8 albumin Homo sapiens 62-75 25923417-7 2016 The silicone PSA episcleral implants in the present study had an average diameter of 3.5 mm and a thickness of 0.8 mm. Silicones 4-12 aminopeptidase puromycin sensitive Homo sapiens 13-16 25923417-8 2016 Drug release from the silicone PSA implants was influenced by drug solubility, implant polymer content, and implant coating. Silicones 22-30 aminopeptidase puromycin sensitive Homo sapiens 31-34 27477414-4 2016 However, the air leak was successfully treated with endobronchial occlusion using two silicone spigots in left B3b and B4, without any adverse effects or aggravation of the infection. Silicones 86-94 CD19 molecule Homo sapiens 111-121 27933322-7 2016 RESULTS: The silicone disclosing procedure performed after micromechanical surface treatment reduced the characteristic shear bond strength to zirconia and lithium disilicate when compared to CTRL. Silicones 13-21 CTRL Bos taurus 192-196 26789595-0 2016 Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1beta and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model. Silicones 154-162 interleukin 6 Mus musculus 128-132 26464557-5 2015 A Cu-sil denture is a denture with holes, lined by a gasket of silicone rubber, the holes thus providing space for remaining natural teeth to emerge into the oral cavity through the denture. Silicones 63-71 STIL centriolar assembly protein Homo sapiens 5-8 26648805-7 2015 The frequently employed types of nasal silicone implant include (1) the boat type in which the silicone implant descends down to the nasal tip, (2) the L-shape in which the silicone implant further extends to the anterior nasal spine (ANS) after passing the tip, and (3) the three-quarter type for which the silicone implant extends down to the upper lateral cartilage. Silicones 39-47 TOR signaling pathway regulator Homo sapiens 139-142 26648805-8 2015 In conjunction with the silicone implant, the cartilages of the ear and the nasal septum are commonly used to create or lengthen tip projection. Silicones 24-32 TOR signaling pathway regulator Homo sapiens 129-132 26648805-12 2015 This nasal tip is the area where severe capsular contracture occurs after insertion of a silicone implant. Silicones 89-97 TOR signaling pathway regulator Homo sapiens 11-14 29632828-5 2015 Fibrinogen, precursor of fibrin, was adsorbed (test protein) on three different polymeric surfaces: silicone, poly(acrylic acid)-coated silicone and poly(allylamine)-coated silicone. Silicones 100-108 fibrinogen beta chain Homo sapiens 0-10 29632828-5 2015 Fibrinogen, precursor of fibrin, was adsorbed (test protein) on three different polymeric surfaces: silicone, poly(acrylic acid)-coated silicone and poly(allylamine)-coated silicone. Silicones 136-144 fibrinogen beta chain Homo sapiens 0-10 29632828-5 2015 Fibrinogen, precursor of fibrin, was adsorbed (test protein) on three different polymeric surfaces: silicone, poly(acrylic acid)-coated silicone and poly(allylamine)-coated silicone. Silicones 136-144 fibrinogen beta chain Homo sapiens 0-10 29632828-8 2015 The novel immuno-based assay showed significantly stronger binding of fibrinogen to both poly(acrylic acid) and poly(allylamine) coated silicone. Silicones 136-144 fibrinogen beta chain Homo sapiens 70-80 26247678-14 2015 The underlying substrate appears to affect the identity of IalphaI TSG-6 HA complexes since different complexes were detected when TM cells were grown on a silicone substrate compared to a rigid plastic surface. Silicones 156-164 TNF alpha induced protein 6 Homo sapiens 67-72 26329233-6 2015 MAE specimens, based on a silicone matrix with isotropic and anisotropic carbonyl iron particle distributions, were subjected to dynamic mechanical analysis under different field and loading configurations. Silicones 26-34 solute carrier family 6 member 1 Homo sapiens 0-3 25978295-8 2015 Based on the obtained data, location-specific silicone rubber-water partition coefficients (Ksr-w; adjusted for temperature and salinity) can be calculated. Silicones 46-54 kinase suppressor of ras 1 Homo sapiens 92-95 24401807-3 2015 Here we present a novel modification to the McFarlane skin flap using sterile silicone. Silicones 78-86 arachidonate 5-lipoxygenase activating protein Rattus norvegicus 59-63 25948656-1 2015 UNLABELLED: A panel of board-certified plastic surgeons chaired by Dr Michael Schwartz convened to discuss their respective experiences with the Sientra High-Strength Cohesive (HSC+) shaped silicone gel breast implants (Sientra, Inc., Santa Barbara, CA). Silicones 190-198 fucosyltransferase 1 (H blood group) Homo sapiens 177-180 25760687-13 2015 Importantly, the early inflammatory response to submuscular silicone implants was inhibited by JM2. Silicones 60-68 forkhead box P3 Homo sapiens 95-98 25799259-2 2015 A new device made up of a divided silicone drain tip to prevent irregular adsorption was reported. Silicones 34-42 TOR signaling pathway regulator Homo sapiens 49-52 25251834-0 2015 Kinetics of Competitive Adsorption between Lysozyme and Lactoferrin on Silicone Hydrogel Contact Lenses and the Effect on Lysozyme Activity. Silicones 71-79 lysozyme Homo sapiens 43-51 25251834-1 2015 PURPOSE: To determine the effect of competitive adsorption between lysozyme and lactoferrin on silicone hydrogel contact lenses and the effect on lysozyme activity. Silicones 95-103 lysozyme Homo sapiens 67-75 25556183-5 2015 We show that although Tec1 plays only a minor role in initial adhesion to the silicone elastomer, it does play a major role in the growth of the basal yeast cell polylayer, vertical extension of hyphae and matrix deposition in the upper portion of the biofilm, final biofilm thickness, penetrability of human white blood cells, and final biofilm integrity (i.e., resistance to fluid flow). Silicones 78-86 Tec1p Saccharomyces cerevisiae S288C 22-26 25098454-0 2015 Chronic silicone embolism syndrome due to PIP breast implant leakage - a new entity? Silicones 8-16 prolactin induced protein Homo sapiens 42-45 25920733-3 2015 It is suggested that, in the space beneath the silicone sheet, the higher humidity and temperature, both generated as a result of prolonged sheeting, especially during hot weather, might have caused the keloid and its neighbouring skin to become soggy. Silicones 47-55 dickkopf like acrosomal protein 1 Homo sapiens 246-251 25706859-5 2015 Modest but unavoidable losses of about 20% of AMG 579 were also found following perfusion through both silicone and polypropylene (Pharmed( ) BPT) collection catheters. Silicones 103-111 amelogenin X-linked Homo sapiens 46-49 25476261-0 2015 CAD/CAM silicone simulator for teaching cheiloplasty: description of the technique. Silicones 8-16 calmodulin 3 Homo sapiens 4-7 25476261-2 2015 We describe a CAD/CAM silicone simulator, which we made using several maxillofacial prosthetic techniques. Silicones 22-30 calmodulin 3 Homo sapiens 18-21 25606485-0 2015 Regulation of Transforming Growth Factor beta1, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring. Silicones 118-126 fibroblast growth factor 2 Homo sapiens 84-114 25606485-7 2015 RESULTS: In both the epidermis and the dermis, the expression of TGF-beta1 (P=0.042 and P=0.042) and PDGF (P=0.043 and P=0.042) was significantly lower in the case of silicone gel sheet-treated scars than in the case of untreated scars. Silicones 167-175 transforming growth factor beta 1 Homo sapiens 65-74 25606485-8 2015 The expression of bFGF in the dermis was significantly higher in the case of silicone gel sheet-treated scars than in the case of untreated scars (P=0.042), but in the epidermis, the expression of bFGF showed no significant difference between the groups (P=0.655). Silicones 77-85 fibroblast growth factor 2 Homo sapiens 18-22 25606485-9 2015 CONCLUSIONS: The levels of TGF-beta1, PDGF, and bFGF are altered by the silicone gel sheet treatment, which might be one of the mechanisms of action in scar prevention. Silicones 72-80 transforming growth factor beta 1 Homo sapiens 27-36 25606485-9 2015 CONCLUSIONS: The levels of TGF-beta1, PDGF, and bFGF are altered by the silicone gel sheet treatment, which might be one of the mechanisms of action in scar prevention. Silicones 72-80 fibroblast growth factor 2 Homo sapiens 48-52 25478871-6 2014 Modifying a commercially available silicone covering through the addition of a polyvinyl chloride material (impermeable to NIR light transmission) produces an acceptable compromise. Silicones 35-43 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 123-126 25598976-4 2014 Mask-Ed (KRS Simulation) is a simulation technique where the educator is hidden behind wearable realistic silicone body props including masks. Silicones 107-115 ankyrin repeat and KH domain containing 1 Homo sapiens 0-4 24342732-6 2014 In the treatment group a silicone tube (SIL/ACTH) was filled with 10 muL ACTH (0.1 mg/mL). Silicones 25-33 proopiomelanocortin Homo sapiens 44-48 32262202-0 2014 Direct observation of the nanocomplex surface reorganization of antifouling silicones containing a highly mobile PEO-silane amphiphile. Silicones 76-85 twinkle mtDNA helicase Homo sapiens 113-116 32262202-2 2014 In this work, the surface of an antifouling polymer matrix - a silicone modified with a highly mobile PEO-silane amphiphile - was characterized while undergoing dynamic surface reorganization in aqueous solution via off-resonance tapping mode atomic force microscopy (AFM) and while monitoring surface changes at a rate >25 mum2 min-1. Silicones 63-71 trafficking protein particle complex subunit 1 Homo sapiens 324-328 32262202-2 2014 In this work, the surface of an antifouling polymer matrix - a silicone modified with a highly mobile PEO-silane amphiphile - was characterized while undergoing dynamic surface reorganization in aqueous solution via off-resonance tapping mode atomic force microscopy (AFM) and while monitoring surface changes at a rate >25 mum2 min-1. Silicones 63-71 CD59 molecule (CD59 blood group) Homo sapiens 329-334 24342732-6 2014 In the treatment group a silicone tube (SIL/ACTH) was filled with 10 muL ACTH (0.1 mg/mL). Silicones 25-33 proopiomelanocortin Homo sapiens 73-77 24983489-5 2014 RESULTS: Cyclic mechanical stretch (36 mm diameter silicone membrane, equibi-axial stretch, 10% elongation, 1 Hz) induced elongation of the cardiomyocytes together with accentuation of Cx43 at the cell poles, and with an orientation of the cell axis between the radial axis and the circumferential axis (mean deviation: 11 from the circumference). Silicones 51-59 gap junction protein, alpha 1 Rattus norvegicus 185-189 24906681-2 2014 The technique involves the educator wearing a silicone mask and or body parts and transforming into a character. Silicones 46-54 ankyrin repeat and KH domain containing 1 Homo sapiens 55-59 25289365-0 2014 Effective Use of a Silicone-induced Capsular Flap in Secondary Asian Rhinoplasty. Silicones 19-27 arachidonate 5-lipoxygenase activating protein Homo sapiens 45-49 24991867-1 2014 Here we report the experimental log maximum fluxes of n = 9 non-steroidal anti-inflammatory drugs (NSAID) through silicone membranes from the lipid mineral oil (experimental (Exp.) Silicones 114-122 muscleblind like splicing regulator 1 Homo sapiens 175-178 24200044-3 2014 A constant PCB concentration of about 1 ng L(-1) was achieved by immersing a large amount of silicone rubber sheets ("dosing sheets") spiked with the target PCBs. Silicones 93-101 pyruvate carboxylase Homo sapiens 11-14 24670384-5 2014 Fibroblasts cultured on skin-soft silicones displayed low mRNA levels of fibrosis-associated genes and increased expression of the matrix metalloproteinases (MMPs) MMP-1 and MMP-3 as compared with collagen gel and plastic cultures. Silicones 34-43 matrix metallopeptidase 1 Homo sapiens 158-162 24670384-5 2014 Fibroblasts cultured on skin-soft silicones displayed low mRNA levels of fibrosis-associated genes and increased expression of the matrix metalloproteinases (MMPs) MMP-1 and MMP-3 as compared with collagen gel and plastic cultures. Silicones 34-43 matrix metallopeptidase 1 Homo sapiens 164-169 24670384-5 2014 Fibroblasts cultured on skin-soft silicones displayed low mRNA levels of fibrosis-associated genes and increased expression of the matrix metalloproteinases (MMPs) MMP-1 and MMP-3 as compared with collagen gel and plastic cultures. Silicones 34-43 matrix metallopeptidase 3 Homo sapiens 174-179 24408910-6 2014 This article looks at current proposals for legislation in the UK following the PIP silicone implant scandal as an example of the risk-regulation premise. Silicones 84-92 prolactin induced protein Homo sapiens 80-83 25327603-2 2014 METHODS: Atherosclerostic plaque model was induced by rapid perivascular carotid silicone collar placement in ApoE(-/-) mice. Silicones 81-89 apolipoprotein E Mus musculus 110-114 24911051-0 2014 Osteopontin (OPN) is an important protein to mediate improvements in the biocompatibility of C ion-implanted silicone rubber. Silicones 109-117 secreted phosphoprotein 1 Homo sapiens 0-11 24911051-0 2014 Osteopontin (OPN) is an important protein to mediate improvements in the biocompatibility of C ion-implanted silicone rubber. Silicones 109-117 secreted phosphoprotein 1 Homo sapiens 13-16 24585370-1 2014 We previously reported nonaqueous silicone elastomer gels (SEGs) for sustained vaginal administration of the CCR5-targeted entry inhibitor maraviroc (MVC). Silicones 34-42 C-C motif chemokine receptor 5 Homo sapiens 109-113 24506943-0 2014 Adherence of Candida albicans to silicone is promoted by the human salivary protein SPLUNC2/PSP/BPIFA2. Silicones 33-41 BPI fold containing family A member 2 Homo sapiens 84-91 24506943-0 2014 Adherence of Candida albicans to silicone is promoted by the human salivary protein SPLUNC2/PSP/BPIFA2. Silicones 33-41 BPI fold containing family A member 2 Homo sapiens 96-102 24506943-5 2014 We show here that a protein of similar size was identified in replicate blots of the eluate from saliva-treated silicone when the blots were probed with antibodies to human SPLUNC2, a salivary protein with reported microbial agglutination properties. Silicones 112-120 BPI fold containing family A member 2 Homo sapiens 173-180 24506943-6 2014 In addition, SPLUNC2 was depleted from saliva that had been incubated with silicone coupons. Silicones 75-83 BPI fold containing family A member 2 Homo sapiens 13-20 24506943-9 2014 We conclude that SPLUNC2 binds to silicone and acts as a receptor for C. albicans adherence to, and subsequent colonization of, voice prosthesis silicone. Silicones 34-42 BPI fold containing family A member 2 Homo sapiens 17-24 24506943-9 2014 We conclude that SPLUNC2 binds to silicone and acts as a receptor for C. albicans adherence to, and subsequent colonization of, voice prosthesis silicone. Silicones 145-153 BPI fold containing family A member 2 Homo sapiens 17-24 24739521-1 2014 Three sisters who carried the BRCA-1 gene mutation had a preventive mastectomy and were reconstructed with silicone breast implants. Silicones 107-115 BRCA1 DNA repair associated Homo sapiens 30-36 24503230-3 2014 All patients who had revision surgery of their PIP silicone arthroplasty in our clinic between 1999 and 2009 were invited for clinical follow-up. Silicones 51-59 prolactin induced protein Homo sapiens 47-50 24280539-0 2014 Inflammatory changes of the nipple areolar complex of a patient with PIP breast implants: a possible immune response to free silicone from gel bleed? Silicones 125-133 prolactin induced protein Homo sapiens 69-72 24360575-6 2014 High expressions of interleukin-1beta and leukotriene B4 receptor 1 in the intra-neural scarring caused by using silicone conduits revealed that the inflammatory mechanism can be inhibited when the conduit is coated with chitosan. Silicones 113-121 interleukin 1 beta Homo sapiens 20-37 24360575-6 2014 High expressions of interleukin-1beta and leukotriene B4 receptor 1 in the intra-neural scarring caused by using silicone conduits revealed that the inflammatory mechanism can be inhibited when the conduit is coated with chitosan. Silicones 113-121 leukotriene B4 receptor Homo sapiens 42-67 25070332-4 2014 A master mix of freshly isolated cells, medium, fibrinogen, and thrombin is pipetted into the casting mold and, over a period of 2 h, polymerizes and forms a fibrin cell block around two silicone posts. Silicones 187-195 coagulation factor II Rattus norvegicus 64-72 24022347-3 2014 Silicone pressure-sensitive adhesive (PSA) polymer was evaluated because of its unique properties of low surface energy, hydrophobicity, low glass transition temperature, high electrical resistance, and barrier to hydrogen ion diffusion. Silicones 0-8 aminopeptidase puromycin sensitive Homo sapiens 38-41 24022347-5 2014 Silicone PSA films showed higher resistance to hydrogen ion diffusion compared with EC films. Silicones 0-8 aminopeptidase puromycin sensitive Homo sapiens 9-12 24022347-6 2014 Verapamil hydrochloride tablets prepared using silicone PSA showed higher hydrophobicity and lower water uptake than EC tablets. Silicones 47-55 aminopeptidase puromycin sensitive Homo sapiens 56-59 24022347-7 2014 Silicone PSA tablets also showed pH-independent release of verapamil and decreased in dimensions during drug dissolution. Silicones 0-8 aminopeptidase puromycin sensitive Homo sapiens 9-12 24716423-1 2014 BACKGROUND: Arabin cervical pessary is a silicone ring pessary for the prevention of preterm birth (PTB] for pregnant women at risk with second trimester short uterine cervix. Silicones 41-49 polypyrimidine tract binding protein 1 Homo sapiens 100-103 24185964-3 2014 We describe a five-step technique using a silicone Penrose drain to aid in the positioning of an endovascular stapling device to obtain vascular control during hepatectomy. Silicones 42-50 activation induced cytidine deaminase Homo sapiens 68-71 24396077-7 2014 RESULTS: The tissue surrounding the silicone disks in the experimental group showed significantly increased levels of collagen type 3, elevated levels of matrix metalloproteinase 9, markedly decreased levels of transforming growth factor beta2, and a reduced CD68 expression in the pericapsular tissue. Silicones 36-44 matrix metallopeptidase 9 Mus musculus 154-180 24396077-7 2014 RESULTS: The tissue surrounding the silicone disks in the experimental group showed significantly increased levels of collagen type 3, elevated levels of matrix metalloproteinase 9, markedly decreased levels of transforming growth factor beta2, and a reduced CD68 expression in the pericapsular tissue. Silicones 36-44 hemoglobin, beta adult minor chain Mus musculus 238-243 24396077-7 2014 RESULTS: The tissue surrounding the silicone disks in the experimental group showed significantly increased levels of collagen type 3, elevated levels of matrix metalloproteinase 9, markedly decreased levels of transforming growth factor beta2, and a reduced CD68 expression in the pericapsular tissue. Silicones 36-44 CD68 antigen Mus musculus 259-263 25023307-3 2014 The major part of an isolated muscle fiber is insulated from the extracellular medium with silicone grease and the tip of a single microelectrode connected to the amplifier is then inserted within the fiber through the silicone layer. Silicones 219-227 TOR signaling pathway regulator Homo sapiens 115-118 23564739-1 2013 PURPOSE: To investigate the impact of lactoferrin and lipids on the kinetic denaturation of lysozyme deposited on silicone and conventional hydrogel lenses, using a complex artificial tear solution (ATS). Silicones 114-122 lysozyme Homo sapiens 92-100 23564739-6 2013 The inclusion of lipids in the ATS significantly increased the lysozyme denaturation on both silicone hydrogel materials (p < 0.001), while in the presence of lactoferrin, lysozyme activity on senofilcon A lenses was significantly higher (p < 0.001). Silicones 93-101 lysozyme Homo sapiens 63-71 23564739-8 2013 CONCLUSIONS: Lactoferrin and lipids have an impact on the denaturation of lysozyme deposited onto silicone hydrogel contact lenses, while conventional hydrogel lenses were unaffected. Silicones 98-106 lysozyme Homo sapiens 74-82 23613464-0 2013 Mediatory role of interleukin-6 in alpha smooth muscle actin induction and myofibroblast formation around silicone tissue expander. Silicones 106-114 interleukin 6 Homo sapiens 18-31 23613464-8 2013 An in vitro degradation study of silicone expander material in pseudoextracellular fluid (PECF) and the alphaSMA expression in fibroblasts incubated with the silicone extract containing PECF has revealed the role of silicone leachants in induction of myofibroblasts. Silicones 158-166 actin alpha 2, smooth muscle, aorta Mus musculus 104-112 23613464-8 2013 An in vitro degradation study of silicone expander material in pseudoextracellular fluid (PECF) and the alphaSMA expression in fibroblasts incubated with the silicone extract containing PECF has revealed the role of silicone leachants in induction of myofibroblasts. Silicones 158-166 actin alpha 2, smooth muscle, aorta Mus musculus 104-112 24146423-1 2013 BACKGROUND: Irrigation of the lacrimal duct with silicone tube intubation (TWS/S) remains the preferred treatment in persisting connatal lacrimal duct stenosis (kTWS). Silicones 49-57 KTWS Homo sapiens 161-165 23752033-6 2013 The fit of the EXP fluxes through silicone membrane to RS was good: r2 = 0.80 if the VEH PG:AQ, 30:70, was the polar solvent (RS1) or r2 = 0.81 if water was the polar solvent (RS2). Silicones 34-42 retinoschisin 1 Homo sapiens 126-129 23725742-0 2013 PIP silicone breast implants: rupture rates based on the explantation of 676 implants in a single surgeon series. Silicones 4-12 prolactin induced protein Homo sapiens 0-3 23635298-12 2013 CONCLUSIONS: Based on study data and the stated selection criteria, the P-4 silicone provided sufficient material contrast to water and edge detail for use across all imaging modalities with the benefits of availability, low cost, dimensional stability, nontoxic, nonflammable, durable, cleanable, and optical clarity. Silicones 76-84 solute carrier family 10 member 4 Homo sapiens 72-75 23089594-2 2013 Mixing propyl- or allyl-modified oligo(ethylene glycol)(PEG), but not the parent hydroxy-terminated oligo(ethylene glycol), with silicone pre-elastomers led a sharp increase in viscosity that preceded the onset of cure. Silicones 129-137 progestagen associated endometrial protein Homo sapiens 56-59 23258145-7 2013 In the FCVB and silicone-treated groups, clinical inflammation almost was abolished; no bacteria were detected in the aqueous humor; TNF-alpha, IL-1beta, and IFN-gamma expression decreased; and relatively normal corneal and retinal architecture were kept after the 30-day treatment. Silicones 16-24 tumor necrosis factor Oryctolagus cuniculus 133-142 23258145-7 2013 In the FCVB and silicone-treated groups, clinical inflammation almost was abolished; no bacteria were detected in the aqueous humor; TNF-alpha, IL-1beta, and IFN-gamma expression decreased; and relatively normal corneal and retinal architecture were kept after the 30-day treatment. Silicones 16-24 interleukin-1 beta Oryctolagus cuniculus 144-152 23258145-7 2013 In the FCVB and silicone-treated groups, clinical inflammation almost was abolished; no bacteria were detected in the aqueous humor; TNF-alpha, IL-1beta, and IFN-gamma expression decreased; and relatively normal corneal and retinal architecture were kept after the 30-day treatment. Silicones 16-24 interferon gamma Oryctolagus cuniculus 158-167 23089594-3 2013 Only in the case of allyl-modified PEG, however, did a low density, closed cell silicone foam form that, in addition to trapped bubbles, contained dispersed PEG droplets. Silicones 80-88 progestagen associated endometrial protein Homo sapiens 35-38 23089594-3 2013 Only in the case of allyl-modified PEG, however, did a low density, closed cell silicone foam form that, in addition to trapped bubbles, contained dispersed PEG droplets. Silicones 80-88 progestagen associated endometrial protein Homo sapiens 157-160 23089594-4 2013 Rheological studies demonstrate that the origins of the viscosity build lie in the formation, shortly after mixing, of organo-PEG stabilized droplets that act as fillers within the silicone pre-elastomers. Silicones 181-189 progestagen associated endometrial protein Homo sapiens 126-129 23089594-7 2013 The surface activity of the propyl- and allyl-PEG compounds themselves facilitates the formation of a colloidal dispersion within the silicone. Silicones 134-142 progestagen associated endometrial protein Homo sapiens 46-49 23089594-8 2013 However, the key to the observed foamed product is the in situ platinum-catalyzed hydrosilylation of the allyl group, prior to or concomitant with silicone cure, leading to PEG-silicone copolymers that are able to stabilize both dispersed PEG droplets and bubbles. Silicones 147-155 progestagen associated endometrial protein Homo sapiens 173-176 23305096-5 2013 Here we investigate the effect of shear stress on DAPK in endothelial cells on glass or silicone membrane substrate. Silicones 88-96 death associated protein kinase 1 Homo sapiens 50-54 22820648-5 2012 For silicone PSA tablets, satisfactory mechanical properties were obtained above the polymer percolation threshold; no cracking or chipping of the tablet was observed above this threshold. Silicones 4-12 aminopeptidase puromycin sensitive Homo sapiens 13-16 23710394-0 2013 A case of atypical mucin balls wearing extended wear of silicone hydrogel lens for therapeutic use. Silicones 56-64 LOC100508689 Homo sapiens 19-24 23823917-6 2013 The Stokes equation predicts that the sedimentation velocity of water droplets dispersed in a continuous silicone oil phase simply depends on the expression (rho - rho0)/eta assuming that the droplet size is constant (where rho is the density of the dispersed water phase, rho0 is the density of the continuous silicone oil phase, and eta is the viscosity of the oil phase). Silicones 105-113 endothelin receptor type A Homo sapiens 170-173 23823917-6 2013 The Stokes equation predicts that the sedimentation velocity of water droplets dispersed in a continuous silicone oil phase simply depends on the expression (rho - rho0)/eta assuming that the droplet size is constant (where rho is the density of the dispersed water phase, rho0 is the density of the continuous silicone oil phase, and eta is the viscosity of the oil phase). Silicones 311-319 endothelin receptor type A Homo sapiens 170-173 24063281-6 2013 We found that when mechanical strain was applied to OS cells cultured on silicone membrane, TN-C mRNA and protein levels were increased 10-fold within 8 h compared to the resting control. Silicones 73-81 tenascin C Homo sapiens 92-96 22820648-7 2012 These results suggest that silicone PSA could eliminate issues related to drug compressibility in the formulation of directly compressed oral controlled release tablets of poorly compressible drug powder such as APAP. Silicones 27-35 aminopeptidase puromycin sensitive Homo sapiens 36-39 23135085-5 2012 U.S. Food and Drug Administration- approved liquid silicone (Silikon ) is emulsified with cross-linked hyaluronic acid through a Luer-Lok to Luer-Lok connector between two 3-cc syringes. Silicones 51-59 serine/threonine kinase 10 Homo sapiens 134-137 23135085-5 2012 U.S. Food and Drug Administration- approved liquid silicone (Silikon ) is emulsified with cross-linked hyaluronic acid through a Luer-Lok to Luer-Lok connector between two 3-cc syringes. Silicones 51-59 serine/threonine kinase 10 Homo sapiens 146-149 28348692-0 2012 Externalized Conductor Cables in QuickSite Left Ventricular Pacing Lead and Riata Right Ventricular Lead in a Single Patient: A Common Problem With Silicone Insulation. Silicones 148-156 Cdk5 and Abl enzyme substrate 1 Homo sapiens 23-29 23235756-9 2012 At the end of the operation, the silicone transanal tube NO COIL , 60-80 mm long, 2 mm thick with a calibre of up to 2 cm, was applied and secured to the perineal skin by two stitches, then removed on the seventh postoperative day if no signs of leakage occurred. Silicones 33-41 coilin Homo sapiens 60-64 23009031-8 2012 In the in vitro studies, THP bound to both silicone and latex catheters, and THP enhanced the adherence of E. coli and P. aeruginosa to both types of catheters. Silicones 43-51 uromodulin Homo sapiens 25-28 22791880-1 2012 PURPOSE: Anaplastic lymphoma kinase (ALK)-negative, T-cell, anaplastic, non-Hodgkin lymphoma (T-ALCL) in patients with textured saline and silicone breast implants is a recently recognized clinical entity for which the etiology and optimal treatment remain unknown. Silicones 139-147 ALK receptor tyrosine kinase Homo sapiens 9-35 22791880-1 2012 PURPOSE: Anaplastic lymphoma kinase (ALK)-negative, T-cell, anaplastic, non-Hodgkin lymphoma (T-ALCL) in patients with textured saline and silicone breast implants is a recently recognized clinical entity for which the etiology and optimal treatment remain unknown. Silicones 139-147 ALK receptor tyrosine kinase Homo sapiens 37-40 22728431-1 2012 The enhancing effect of supersaturation generated by amorphous ketotifen in silicone pressure-sensitive adhesive matrices (PSA) on the transdermal absorption was evaluated in vivo using hairless rats, and it was compared with the increase of drug amount in skin tissues. Silicones 76-84 aminopeptidase puromycin sensitive Rattus norvegicus 123-126 22732590-5 2012 We describe a simple system for the stimulation of the TCR/CD3 complex and the CD28 receptor using substrates with variable rigidity manufactured from poly(dimethylsiloxane), a biocompatible silicone elastomer. Silicones 191-199 CD28 molecule Homo sapiens 79-83 22286447-12 2012 CONCLUSION: The authors" results indicate that silicone implants trigger a specific, antigen-driven local immune response through activated TH1/TH17 cells, suggesting that ensuing fibrosis is promoted by the production of profibrotic cytokines as a consequence of faltering function of local T regulatory cells. Silicones 47-55 negative elongation factor complex member C/D Homo sapiens 140-143 22560492-0 2012 ABC copolymer silicone surfactant templating for biomimetic silicification. Silicones 14-22 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 22564255-0 2012 Stable release of BDNF from the fibroblast cell line NIH3T3 grown on silicone elastomers enhances survival of spiral ganglion cells in vitro and in vivo. Silicones 69-77 brain derived neurotrophic factor Mus musculus 18-22 22564255-5 2012 Therefore, the capacity of brain-derived neurotrophic factor (BDNF)-secreting NIH3T3 cells grown on cylindrically shaped silicone elastomers (SE) to exert local and sustained neuroprotective effects was assessed in vitro and in vivo. Silicones 121-129 brain derived neurotrophic factor Mus musculus 62-66 22743898-1 2012 BACKGROUND: Several studies have reported adverse immunological effects of silicone due to their ability to induce proinflammatory molecules, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). Silicones 75-83 tumor necrosis factor Homo sapiens 150-177 22743898-1 2012 BACKGROUND: Several studies have reported adverse immunological effects of silicone due to their ability to induce proinflammatory molecules, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). Silicones 75-83 tumor necrosis factor Homo sapiens 179-188 22743898-1 2012 BACKGROUND: Several studies have reported adverse immunological effects of silicone due to their ability to induce proinflammatory molecules, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). Silicones 75-83 interleukin 6 Homo sapiens 194-207 22743898-1 2012 BACKGROUND: Several studies have reported adverse immunological effects of silicone due to their ability to induce proinflammatory molecules, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). Silicones 75-83 interleukin 6 Homo sapiens 209-213 22743898-10 2012 Silicone microparticles at 100 mug/ml, however, significantly induced the production and gene expression of TNF-alpha, IL-6, and IFN-gamma by peripheral blood mononuclear cells. Silicones 0-8 tumor necrosis factor Homo sapiens 108-117 22743898-10 2012 Silicone microparticles at 100 mug/ml, however, significantly induced the production and gene expression of TNF-alpha, IL-6, and IFN-gamma by peripheral blood mononuclear cells. Silicones 0-8 interleukin 6 Homo sapiens 119-123 22743898-10 2012 Silicone microparticles at 100 mug/ml, however, significantly induced the production and gene expression of TNF-alpha, IL-6, and IFN-gamma by peripheral blood mononuclear cells. Silicones 0-8 interferon gamma Homo sapiens 129-138 22885483-9 2012 Between two abutment preparations, the percentage of linear dimensional change of Zhermeck silicone impression increased 0.214% (45.1mum) at 1h and decreased 0.019% (4.0mum) at 48h while 3M silicone impression increased 0.087%(18.2mum) at 1h and decreased 0.09% (18.8mum) at 48h. Silicones 91-99 latexin Homo sapiens 133-136 22415150-0 2012 Elevated tear interleukin-6 and interleukin-8 levels associated with silicone hydrogel and conventional hydrogel contact lens wear. Silicones 69-77 interleukin 6 Homo sapiens 14-27 22415150-0 2012 Elevated tear interleukin-6 and interleukin-8 levels associated with silicone hydrogel and conventional hydrogel contact lens wear. Silicones 69-77 C-X-C motif chemokine ligand 8 Homo sapiens 32-45 22359358-9 2012 Covering the silicone discs with an anti-FAS-antibody coating followed by a coincubation with FAS-sensitive T-cells allowed highly significant detection of caspase-3. Silicones 13-21 caspase 3 Homo sapiens 156-165 22179487-7 2012 The analytical performance of this device as the detector for digital ELISA compared favourably to the standard method, i.e., glass arrays mechanically sealed against a silicone gasket; prostate specific antigen (PSA) could be detected from 0.011 pg mL(-1) up to 100 pg mL(-1). Silicones 169-177 kallikrein related peptidase 3 Homo sapiens 213-216 22384967-3 2012 The neurons that respond to fat also respond to silicone and paraffin oil, indicating that the sensing is texture-specific not chemo-specific. Silicones 48-56 FAT atypical cadherin 1 Homo sapiens 28-31 22505893-3 2012 A patient with total glossectomy can be rehabilitated by silicone tongue prosthesis as an aid to improve his speech and swallowing. Silicones 57-65 activation induced cytidine deaminase Homo sapiens 90-93 22312930-1 2012 OBJECTIVES: Our goals were to determine whether a bovine milk product containing anti-Candida albicans immunoglobulin A antibodies ("immune milk") could reduce the adherence of C albicans to voice prosthesis silicone in vitro, and whether administration of the milk could reduce C albicans colonization and voice prosthesis damage in vivo. Silicones 208-216 Weaning weight-maternal milk Bos taurus 140-145 23366777-4 2012 The ceramic package is casted in medical grade silicone adhesive, for which we identified MED2-4013 as a promising candidate. Silicones 47-55 mediator complex subunit 29 Homo sapiens 90-94 21839505-0 2011 The association of matrix Gla protein isomers with calcification in capsules surrounding silicone breast implants. Silicones 89-97 matrix Gla protein Homo sapiens 19-37 22276126-7 2012 Here we showed that the gat2/gat2 mutant failed to form biofilms on the plastic and silicone surfaces. Silicones 84-92 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 Mus musculus 24-28 22276126-7 2012 Here we showed that the gat2/gat2 mutant failed to form biofilms on the plastic and silicone surfaces. Silicones 84-92 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 Mus musculus 29-33 25734044-2 2012 The association of anaplastic lymphoma kinase (ALK) negative anaplastic large cell lymphoma (ALCL), a very rare form of primary breast lymphoma, with silicone-filled breast implants has been suggested and several case reports supported this proposal, especially in Western countries. Silicones 150-158 ALK receptor tyrosine kinase Homo sapiens 19-45 25734044-2 2012 The association of anaplastic lymphoma kinase (ALK) negative anaplastic large cell lymphoma (ALCL), a very rare form of primary breast lymphoma, with silicone-filled breast implants has been suggested and several case reports supported this proposal, especially in Western countries. Silicones 150-158 ALK receptor tyrosine kinase Homo sapiens 47-50 25734044-3 2012 Here we describe one of the first cases of primary breast ALK-negative ALCL in association with saline-filled silicone breast implants evaluated in Iran, where the rising number of breast reconstructive and aesthetic surgeries would commit both surgical pathologists and plastic surgeons to be familiar with this entity. Silicones 110-118 ALK receptor tyrosine kinase Homo sapiens 58-61 21839505-3 2011 In this study we investigated capsules from silicone gel-filled breast prostheses to test the hypothesis that this calcification might be regulated by the small vitamin K-dependent protein, matrix Gla protein (MGP), a potent inhibitor of arterial calcification, or by Fetuin-A, a hepatocyte-derived glycoprotein also implicated as a regulator of pathologic calcification. Silicones 44-52 matrix Gla protein Homo sapiens 190-208 21839505-3 2011 In this study we investigated capsules from silicone gel-filled breast prostheses to test the hypothesis that this calcification might be regulated by the small vitamin K-dependent protein, matrix Gla protein (MGP), a potent inhibitor of arterial calcification, or by Fetuin-A, a hepatocyte-derived glycoprotein also implicated as a regulator of pathologic calcification. Silicones 44-52 matrix Gla protein Homo sapiens 210-213 21839505-9 2011 These findings demonstrate that MGP, in its vitamin K-activated conformer, may represent a pharmacological target to sustain the health of the peri-prosthetic tissue which encapsulates silicone breast implants as well as other implanted silicone medical devices. Silicones 185-193 matrix Gla protein Homo sapiens 32-35 21839505-9 2011 These findings demonstrate that MGP, in its vitamin K-activated conformer, may represent a pharmacological target to sustain the health of the peri-prosthetic tissue which encapsulates silicone breast implants as well as other implanted silicone medical devices. Silicones 237-245 matrix Gla protein Homo sapiens 32-35 21463132-4 2011 We applied a linear HNK-1 mimetic or a functionally inactive control peptide in silicone cuffs used to reconstruct the cut femoral nerves of adult cynomolgus monkeys (Macaca fascicularis). Silicones 80-88 beta-1,3-glucuronyltransferase 1 Homo sapiens 20-25 21729665-5 2011 The finding of 28 cases of breast ALK-1(-) ALCL occurring in patients with implants compared with 10 cases in women without implants is in favor of an association between silicone breast prostheses and ALK-1(-) ALCL. Silicones 171-179 activin A receptor like type 1 Homo sapiens 34-39 21729665-5 2011 The finding of 28 cases of breast ALK-1(-) ALCL occurring in patients with implants compared with 10 cases in women without implants is in favor of an association between silicone breast prostheses and ALK-1(-) ALCL. Silicones 171-179 activin A receptor like type 1 Homo sapiens 34-42 21976180-6 2011 NGF administration was made inside the epineural flap using a silicone reservoir connected to a silicone tube. Silicones 62-70 beta-nerve growth factor Oryctolagus cuniculus 0-3 21976180-6 2011 NGF administration was made inside the epineural flap using a silicone reservoir connected to a silicone tube. Silicones 96-104 beta-nerve growth factor Oryctolagus cuniculus 0-3 21623875-5 2011 METHODS: Penetration of Pc 4 was evaluated using standard Franz-type vertical diffusion cell experiments on surrogate materials (silicone membranes) and laser-scanning confocal microscopy of normal skin biopsy samples from human volunteers. Silicones 129-137 proprotein convertase subtilisin/kexin type 4 Homo sapiens 24-28 21453967-2 2011 We show that uncoated silicone and polystyrene are both potent activators of the complement system, measured both as activated, deposited C3b and quantifying fluid-phase release of the cleavage fragment C3c. Silicones 22-30 complement C3 Homo sapiens 138-141 21518076-7 2011 RESULTS: The rolling distance was reduced with a decrease in CBR, and a thinner cohesive silicone (CBR 1/60) layer demonstrated a higher peak load. Silicones 89-97 carbonyl reductase 1 Homo sapiens 99-104 21272673-0 2011 Role of toll-like receptor 4 in the inflammation reaction surrounding silicone prosthesis. Silicones 70-78 toll-like receptor 4 Mus musculus 8-28 21173699-1 2011 PURPOSE: To determine the association between mucin ball formation and corneal infiltrative events (CIEs) during continuous wear with lotrafilcon A silicone hydrogel contact lenses. Silicones 148-156 LOC100508689 Homo sapiens 46-51 21272673-3 2011 The aim of our study was to assess the role of TLR4 in the foreign body reaction to a silicone shell prosthesis. Silicones 86-94 toll-like receptor 4 Mus musculus 47-51 21272673-8 2011 Our study suggests, from this foreign body response model against silicone in mice, that TLR4 plays a key role in the reaction process around silicone implants. Silicones 66-74 toll-like receptor 4 Mus musculus 89-93 21272673-8 2011 Our study suggests, from this foreign body response model against silicone in mice, that TLR4 plays a key role in the reaction process around silicone implants. Silicones 142-150 toll-like receptor 4 Mus musculus 89-93 21242805-1 2011 A dartos musculocutaneous flap was used to cover a defect of a silicone-treated granulomatous penis after a burn. Silicones 63-71 arachidonate 5-lipoxygenase activating protein Homo sapiens 26-30 21142625-1 2011 Laparoscopic adjustable silicone banding (LAP-BAND) has rapidly gained acceptance and is now considered the most common bariatric operation. Silicones 24-32 LAP Homo sapiens 42-45 21403531-0 2011 Alar cartilage used as tip grafts in secondary silicone augmentation rhinoplasty in Chinese patients. Silicones 47-55 TOR signaling pathway regulator Homo sapiens 23-26 21403531-1 2011 OBJECTIVES: To introduce the use of alar cartilage as tip grafts in secondary silicone augmentation rhinoplasty in Chinese patients and to assess its short-term results in nasal tip modification. Silicones 78-86 TOR signaling pathway regulator Homo sapiens 54-57 21403531-9 2011 CONCLUSIONS: The use of alar cartilage as tip grafts provides a new option for Chinese patients who were dissatisfied with primary silicone augmentation rhinoplasty, specially those with short nose, less projection, and bad nasal tip definition. Silicones 131-139 TOR signaling pathway regulator Homo sapiens 42-45 21539085-3 2011 Implants placement to rats treated with IL-2 resulted in the formation of a thicker capsule with the signs of sclerosis, fibrosis and hyialinosis; all the capsular structures were heavily infiltrated with macrophages, which contained phagocytozed silicone fragments. Silicones 247-255 interleukin 2 Rattus norvegicus 40-44 21124130-0 2010 Vascular endothelial growth factor overexpression positively modulates the characteristics of periprosthetic tissue of polyurethane-coated silicone breast implant in rats. Silicones 139-147 vascular endothelial growth factor A Rattus norvegicus 0-34 21124130-10 2010 Immunohistochemical analysis revealed high levels of transforming growth factor-beta and VEGF in the capsules around the polyurethane-coated silicone implants when compared with the textured-surface silicone implants. Silicones 141-149 vascular endothelial growth factor A Rattus norvegicus 89-93 21124130-11 2010 CONCLUSION: These findings suggest that the intense VEGF expression in capsules around the polyurethane-coated silicone implant is able to improve the tissue vascularization, resulting in a softer capsule compared with the textured-surface silicone implant. Silicones 111-119 vascular endothelial growth factor A Rattus norvegicus 52-56 21124130-11 2010 CONCLUSION: These findings suggest that the intense VEGF expression in capsules around the polyurethane-coated silicone implant is able to improve the tissue vascularization, resulting in a softer capsule compared with the textured-surface silicone implant. Silicones 240-248 vascular endothelial growth factor A Rattus norvegicus 52-56 20725963-1 2010 The formation of hypertrophic scars (HSF) is a frequent medical outcome of wound repair and often requires further therapy with treatments such as silicone gel sheets (SGS) or apoptosis-inducing agents, including bleomycin. Silicones 147-155 interleukin 6 Homo sapiens 37-40 20675954-5 2010 Mak Press also showed a significantly smaller weight of automixed silicone material than the other groups (p<0.05), while SR-Ivocap and Success showed similar adaptation accuracy to the compression-molding denture. Silicones 66-74 male germ cell associated kinase Homo sapiens 0-3 20419302-5 2010 Silicone implants were used beneath the flap in 80% of cases to improve symmetry. Silicones 0-8 arachidonate 5-lipoxygenase activating protein Homo sapiens 40-44 20541255-4 2010 We established that mechanically-induced VEGF entrapment using stretched silicone membrane was saturable after 3 exposures at high frequency stretches (5Hz). Silicones 73-81 vascular endothelial growth factor A Homo sapiens 41-45 20695393-10 2010 CONCLUSION: Nasal plasty by using auto-cartilage grafting and silicone implant combined with trimming the lower lateral cartilages and thinning the superfluous tissue of the tip is an effective method especially for round or bulbous nasal tip. Silicones 62-70 TOR signaling pathway regulator Homo sapiens 239-242 21054968-15 2010 At 6 months after vitrectomy with gas tamponade in 15 patients, their IGFBP-6 level in serum decreased comparing that of preoperation (65.4 +- 31.8) ng/L (t = 11.10, P < 0.05) and encircling failure group was (109.2 +- 6.6) ng/L, it was higher than that of normal and silicone tamponade groups (t = 3.16, 2.77; P < 0.05). Silicones 271-279 insulin like growth factor binding protein 6 Homo sapiens 70-77 21629458-4 2010 This paper describes a novel technique for retention of silicone orbital prosthesis using acrylic resin base attached to maxillary obturator with the help of pin and socket of an electric plug wherein the latter is attached to the eye prosthesis with the help of a mechanical undercut. Silicones 56-64 dynein light chain LC8-type 1 Homo sapiens 158-161 20485035-7 2010 Itch was the only item that worsened in the group self-drying silicone gel. Silicones 62-70 itchy E3 ubiquitin protein ligase Homo sapiens 0-4 19733877-5 2010 During the anastomosis, we kept the jejunum fixed in position with a silicone band Lig-A-Loops, thereby preventing the intestine from slipping off the shaft of the stapler. Silicones 69-77 ubiquitin conjugating enzyme E2 K Homo sapiens 83-86 20458346-7 2010 Inimitable immunofluorescent microscopy represented in our high magnification images of vinculin, vimentin, and the actin cytoskeleton highlights the differences in fibroblast adhesion between fabricated silicone surfaces. Silicones 204-212 vinculin Homo sapiens 88-96 20458346-7 2010 Inimitable immunofluorescent microscopy represented in our high magnification images of vinculin, vimentin, and the actin cytoskeleton highlights the differences in fibroblast adhesion between fabricated silicone surfaces. Silicones 204-212 vimentin Homo sapiens 98-106 19913613-3 2010 ATR-FTIR spectroscopic imaging of membrane diffusion was used to gain an understanding of when the boundary conditions applied to Fick"s second law, used to model the diffusion of permeants across the silicone membrane do not hold. Silicones 201-209 ATR serine/threonine kinase Homo sapiens 0-3 20091922-3 2010 The objective of this study was to assess the effects of three specific concentrations of silicone resin particles (12 mum average diameter) in conjunction with either platelet-derived growth factor (PDGF-BB) or basic fibroblast growth factor (bFGF) on fibroblast cell proliferation, collagen synthesis, cell morphology, and migration through in vitro assays and a monolayer scratch wound model. Silicones 90-98 fibroblast growth factor 2 Homo sapiens 244-248 19913613-4 2010 The imaging experiments indicated that when the solvent was not taken up appreciably into the membrane, the presence of discrete solvent pools between the ATR crystal and the silicone membrane can affect the diffusion profile of the permeant. Silicones 175-183 ATR serine/threonine kinase Homo sapiens 155-158 20178690-0 2010 Kinetics of lysozyme activity recovered from conventional and silicone hydrogel contact lens materials. Silicones 62-70 lysozyme Homo sapiens 12-20 19801581-4 2010 A silicone stent was used to splint the CAA for the first 12 months. Silicones 2-10 teashirt zinc finger homeobox 1 Homo sapiens 40-43 21089199-1 2010 In this report, two cases presenting with CTS including a fracture of the silicone implant for Kienbock"s disease after replacement over 20 years postoperatively where CTR ceased the symptoms of CTS. Silicones 74-82 transthyretin Homo sapiens 42-45 21089199-1 2010 In this report, two cases presenting with CTS including a fracture of the silicone implant for Kienbock"s disease after replacement over 20 years postoperatively where CTR ceased the symptoms of CTS. Silicones 74-82 calcitonin receptor Homo sapiens 168-171 21089199-1 2010 In this report, two cases presenting with CTS including a fracture of the silicone implant for Kienbock"s disease after replacement over 20 years postoperatively where CTR ceased the symptoms of CTS. Silicones 74-82 transthyretin Homo sapiens 195-198 21089199-3 2010 There was an unlikely association between the fracture of the implant and CTS, which was confirmed by the operative findings of tenosynovitis and thickness of the degenerated transverse ligament without a significant protrusion of the silicone implant. Silicones 235-243 transthyretin Homo sapiens 74-77 20178690-1 2010 We determined the activity of lysozyme recovered from various conventional and silicone hydrogel (SH) contact lens materials as a function of time, using an in vitro model. Silicones 79-87 lysozyme Homo sapiens 30-38 19145631-5 2009 Silicone induced production of TNF-alpha and IL-6 in all three groups. Silicones 0-8 tumor necrosis factor Homo sapiens 31-40 19806455-4 2009 Silicone stamps fabricated from the photomasks deposit fibronectin patterns to guide local cellular alignment. Silicones 0-8 fibronectin 1 Rattus norvegicus 55-66 19885495-0 2009 Lipase catalyzed synthesis of silicone polyesters. Silicones 30-38 PAN0_003d1715 Moesziomyces antarcticus 0-6 19885495-1 2009 Immobilized Candida antarctica lipase B (CALB) was successfully employed as a catalyst to synthesize silicone aromatic polyesters by the transesterification of dimethyl terephthalate with alpha,omega-bis(hydroxyalkyl)-terminated poly(dimethylsiloxane) in toluene under mild reaction conditions. Silicones 101-109 PAN0_003d1715 Moesziomyces antarcticus 31-37 19918336-2 2009 A series of anecdotal case reports and a recent epidemiological case-control study have suggested a possible association between silicone implant and the development of primary breast ALK1-negative anaplastic large cell lymphoma (ALCL), a rare type of peripheral T-cell lymphoma. Silicones 129-137 secretory leukocyte peptidase inhibitor Homo sapiens 184-188 19918336-3 2009 In this report, we describe an additional case of primary breast ALK1-negative ALCL in the fibrous capsule and cystic fluid of silicone breast implant in a 58 year old woman who underwent breast reconstructive surgery after lumpectomy for her infiltrating breast adenocarcinoma. Silicones 127-135 secretory leukocyte peptidase inhibitor Homo sapiens 65-69 19918336-6 2009 We will also review the case reports and case series published in the English literature and discuss our current understanding of silicone implant in primary breast ALK1-negative ALCL. Silicones 130-138 secretory leukocyte peptidase inhibitor Homo sapiens 165-169 19145631-5 2009 Silicone induced production of TNF-alpha and IL-6 in all three groups. Silicones 0-8 interleukin 6 Homo sapiens 45-49 19145631-6 2009 Notably, elevated production of IL-6 was observed in nonstimulated PBMC and also the percentage of CD4(+)CD69(+) T cells was higher in PHA-stimulated PBMC from individuals with silicone injection-related adverse reactions when compared with other two groups. Silicones 177-185 interleukin 6 Homo sapiens 32-36 19145631-6 2009 Notably, elevated production of IL-6 was observed in nonstimulated PBMC and also the percentage of CD4(+)CD69(+) T cells was higher in PHA-stimulated PBMC from individuals with silicone injection-related adverse reactions when compared with other two groups. Silicones 177-185 CD4 molecule Homo sapiens 99-102 19330370-11 2009 In comparison to grade I, the capsular tissue from patients with Baker II and III/IV fibrosis showed a significant increase for TIMP-1 and TIMP-2 (p < 0.05) in both smooth and textured silicone implants. Silicones 188-196 TIMP metallopeptidase inhibitor 1 Homo sapiens 128-134 19330370-11 2009 In comparison to grade I, the capsular tissue from patients with Baker II and III/IV fibrosis showed a significant increase for TIMP-1 and TIMP-2 (p < 0.05) in both smooth and textured silicone implants. Silicones 188-196 TIMP metallopeptidase inhibitor 2 Homo sapiens 139-145 19252421-1 2009 PURPOSE: To determine the quantity of total protein, total lysozyme, and the conformational state of lysozyme deposited on a novel, lathe-cut silicone hydrogel (SiHy) contact lens material (sifilcon A) after 3 months of wear. Silicones 142-150 lysozyme Homo sapiens 101-109 19188049-4 2009 Finally, the semi-interpenetrating network (semi-IPN) hydrogel was achieved by reacting with silicone marcomer and Pluronic F127 triblock copolymer under UV-photopolymerization (mSi-PU/F127). Silicones 93-101 phenylalkylamine Ca2+ antagonist (emopamil) binding protein Mus musculus 178-181 19188049-11 2009 Overall results demonstrated that the mSi-PU/F127 semi-IPN hydrogel provided silicone hydrogel materials not only having relatively high oxygen permeability and a relatively low modulus, but also enhancing hydrophilicity and anti-protein adsorption. Silicones 77-85 phenylalkylamine Ca2+ antagonist (emopamil) binding protein Mus musculus 38-41 19103514-9 2009 The delivery of GDNF via the affinity-based delivery system can enhance peripheral nerve regeneration through a silicone conduit across a critical nerve gap and offers insight into potential future alternatives to the treatment of peripheral nerve injuries. Silicones 112-120 glial cell derived neurotrophic factor Rattus norvegicus 16-20 19407614-0 2009 The connexin43 carboxyl-terminal peptide ACT1 modulates the biological response to silicone implants. Silicones 83-91 gap junction protein alpha 1 Homo sapiens 4-14 19407614-0 2009 The connexin43 carboxyl-terminal peptide ACT1 modulates the biological response to silicone implants. Silicones 83-91 TRAF3 interacting protein 2 Homo sapiens 41-45 19407614-10 2009 RESULTS: ACT1 modulated the wound-healing response to silicone implants by attenuating neutrophil infiltration, increasing vascularity of the capsule tissue, reducing type I collagen deposition around the implant, and reducing the continued presence of contractile myofibroblasts. Silicones 54-62 TRAF3 interacting protein 2 Homo sapiens 9-13 18929368-1 2009 A headspace sampling method is described for concentrating milk volatiles onto a multi-channel open tubular silicone rubber trap (MCT) for thermal desorption into a GC-FID. Silicones 108-116 solute carrier family 16 member 1 Homo sapiens 130-133 18841402-0 2009 Disinfection of maxillofacial silicone elastomer using a novel antimicrobial agent: recombinant human beta-defensin-3. Silicones 30-38 defensin beta 103B Homo sapiens 102-117 18841402-2 2009 The aim of the study was to evaluate the efficacy of human beta-defensin-3 (HBD3) on the reduction of two resistant bacteria species from the surface of maxillofacial silicone elastomer. Silicones 167-175 defensin beta 103B Homo sapiens 59-74 18841402-2 2009 The aim of the study was to evaluate the efficacy of human beta-defensin-3 (HBD3) on the reduction of two resistant bacteria species from the surface of maxillofacial silicone elastomer. Silicones 167-175 defensin beta 103B Homo sapiens 76-80 19277394-1 2009 The combination of IrCl(CO)(PPh3)2 with 1,1,3,3-tetramethyldisiloxane or poly(methylhydrosiloxane) (PMHS) is found to be an efficient catalyst system for the preparation of aldenamines from carboxamides; in particular, facile removal of silicone and iridium residues from the product can be achieved by the use of PMHS. Silicones 237-245 caveolin 1 Homo sapiens 28-32 18984890-1 2008 CONTEXT: Recently, we identified 2 patients with anaplastic large T-cell lymphoma (ALCL) negative for tyrosine kinase anaplastic lymphoma kinase (ALK-negative) in the fibrous capsule of silicone breast prostheses, placed for cosmetic reasons. Silicones 186-194 ALK receptor tyrosine kinase Homo sapiens 146-149 18157663-7 2008 A drop of the phosphate buffer solution with the AsA was put on the sensing area of the oxygen electrode, and the FMO-3 immobilized membrane was placed on the oxygen electrode and covered with a supporting Nylon mesh net which was secured with a silicone O-ring. Silicones 246-254 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 114-119 19087721-6 2008 RESULTS: The silicone-rubber-membrane covered by Ang II treated HSCs showed obvious wrinkles indicating the contraction of HSCs. Silicones 13-21 angiogenin Homo sapiens 49-52 18194484-2 2008 It is still unclear if changes in the GH/IGF-I axis after laparoscopic-adjustable silicone gastric banding (LASGB) are associated with changes of body composition. Silicones 82-90 insulin like growth factor 1 Homo sapiens 41-46 18797093-2 2008 The use of powder colors to help develop a simplified silicone shade guide to aid in the fabrication of silicone facial prostheses for Indian patients has been described here. Silicones 54-62 activation induced cytidine deaminase Homo sapiens 78-81 18797093-2 2008 The use of powder colors to help develop a simplified silicone shade guide to aid in the fabrication of silicone facial prostheses for Indian patients has been described here. Silicones 104-112 activation induced cytidine deaminase Homo sapiens 78-81 18521006-1 2008 Expression of transcription factor ATF3 in sensory neurons in dorsal root ganglion and in Schwann cells in sciatic nerve of diabetic (BB and Goto-Kakizaki rats; experimental models of types 1 and 2 diabetes, respectively) and healthy rats were examined by immunocytochemistry after nerve compression (silicone tube) for 3, 6 or 14 days. Silicones 301-309 activating transcription factor 3 Rattus norvegicus 35-39 18682782-2 2008 METHODS: We present 23 patients treated with the Canica ABRA dynamic wound closure system that re-approximated open abdomens with silicone elastomers placed transfascially across the wound. Silicones 130-138 actin binding Rho activating protein Homo sapiens 56-60 18532870-3 2008 This paper describes a technique to manufacture realistic silicone AAA models for use with experimental studies. Silicones 58-66 AAA1 Homo sapiens 67-70 18532870-7 2008 Silicone rubber forms the basis of the resulting AAA model. Silicones 0-8 AAA1 Homo sapiens 49-52 18214737-0 2008 Conformational and quantitative characterization of lysozyme extracted from galyfilcon and senofilcon silicone hydrogel contact lenses. Silicones 102-110 lysozyme Homo sapiens 52-60 17557153-1 2008 A microfluidic network (microFN) etched into a silicon wafer was used to deliver protein solutions containing different concentrations of the axonal guidance molecule ephrinA5 onto a silicone stamp. Silicones 183-191 ephrin A5 Gallus gallus 167-175 18214737-1 2008 PURPOSE: To compare two solvents for retrieval of lysozyme deposited on a silicone hydrogel (SH) contact lens material galyfilcon A (GA; Acuvue Advance). Silicones 74-82 lysozyme Homo sapiens 50-58 18437917-5 2007 We found that fibronectin coating increased adhesion to silicone chamber surface, however, it did not show significant effect on proliferation of hMSCs. Silicones 56-64 fibronectin 1 Homo sapiens 14-25 17498998-2 2007 Mucin balls, which form in the tear layer in patients wearing silicone hydrogel lenses, can penetrate the full thickness of the epithelium, leading to activation of keratocytes in the underlying anterior stroma. Silicones 62-70 LOC100508689 Homo sapiens 0-5 17150406-3 2007 Because disiloxane (H(3)SiOSiH(3)) is the smallest molecule in the set which runs through small siloxanes like hexamethyldisiloxane (CH(3))3SiOSi(CH(3))3 to silicone polymers, its energetic, structural and vibrational features have been investigated in detail using density functional theory (B3LYP), post Hartree-Fock methods (MP2 and CCSD(T)) and basis sets up to spdfg quality. Silicones 157-165 tryptase pseudogene 1 Homo sapiens 328-331 17084411-12 2007 IL-6 levels were highest in patients with TRAM operations, being the most extensive procedure studied, whereas the highest IL-8 levels were seen in women with a saline filled silicone implant suggesting immunomodulation by foreign material. Silicones 175-183 C-X-C motif chemokine ligand 8 Homo sapiens 123-127 17502748-0 2007 Quantity and conformation of lysozyme deposited on conventional and silicone hydrogel contact lens materials using an in vitro model. Silicones 68-76 lysozyme Homo sapiens 29-37 17502748-1 2007 PURPOSE: To determine the activity of hen egg lysozyme (HEL) deposited on conventional and silicone hydrogel contact lens materials by using an in vitro model. Silicones 91-99 lysozyme Homo sapiens 46-54 17502748-11 2007 CONCLUSIONS: Silicone hydrogel lenses acquire less lysozyme deposit than conventional group II (Proclear) or group IV (ACUVUE 2) lenses do, and the levels of activity of the lysozyme are highly variable between materials. Silicones 13-21 lysozyme Homo sapiens 51-59 17502748-11 2007 CONCLUSIONS: Silicone hydrogel lenses acquire less lysozyme deposit than conventional group II (Proclear) or group IV (ACUVUE 2) lenses do, and the levels of activity of the lysozyme are highly variable between materials. Silicones 13-21 lysozyme Homo sapiens 174-182 17178157-0 2007 Selective control of liver and kidney cells migration during organotypic cocultures inside fibronectin-coated rectangular silicone microchannels. Silicones 122-130 fibronectin 1 Homo sapiens 91-102 17985545-3 2007 FINDINGS: Schwann cell transduction with the pREV-retrovirus, for expression of Sialyl-Transferase-X, resulting in conferring Polysialyl-residues (PSA) on NCAM, increases their motility in-vitro and ensures nerve regeneration through silicone tubes after end-to-side neurorraphy in the rat sciatic nerve model, thus significantly promoting fiber maturation and functional outcome. Silicones 234-242 neural cell adhesion molecule 1 Rattus norvegicus 155-159 17875216-9 2007 Women with silicone implants, however, had unexpectedly low serum globulin and immunoglobulin levels, with or without the subsequent development of CTD. Silicones 11-19 CTD Homo sapiens 148-151 16817187-0 2006 Characterization of EGF coupling to aminated silicone rubber surfaces. Silicones 45-53 epidermal growth factor Homo sapiens 20-23 16616240-11 2006 Compared with controls, the silicone emboli group had an increased level of IL-13 on day 1, an increased level of MCP-1 on day 4, and an increase in the levels of all inflammatory mediators on day 14 (P < .05). Silicones 28-36 interleukin 13 Rattus norvegicus 76-81 16616240-11 2006 Compared with controls, the silicone emboli group had an increased level of IL-13 on day 1, an increased level of MCP-1 on day 4, and an increase in the levels of all inflammatory mediators on day 14 (P < .05). Silicones 28-36 C-C motif chemokine ligand 2 Rattus norvegicus 114-119 16174526-9 2006 Silicone shunts coated with SAMs may be suitable for future clinical applications to improve the treatment of hydrocephalus. Silicones 0-8 methionine adenosyltransferase 1A Homo sapiens 28-32 16165242-2 2005 A solvent casting method using silicone-typed PSA was employed, and n-hexane, an original solvent for the PSA and one more solvent, dichloromethane, tetrahydrofuran, acetone, ethyl acetate or toluene, were used for complete dissolution of ketotifen and high dispersion in an amorphous state of the drug. Silicones 31-39 aminopeptidase puromycin sensitive Mus musculus 46-49 16417248-2 2006 A generic route to biocompatible silicone elastomers is described involving high yield surface functionalization of standard silicones with hydrosilanes, hydrosilylation using asymmetric, allyl-, NSC-terminated PEO of narrow molecular weight, and covalent modification in one step with amine-containing biological molecules including oligopeptides (YIGSR, RGDS), proteins (EGF, albumin, fibrinogen, mucin), and glycosaminoglycans (heparin). Silicones 33-41 ral guanine nucleotide dissociation stimulator Homo sapiens 356-360 16417248-2 2006 A generic route to biocompatible silicone elastomers is described involving high yield surface functionalization of standard silicones with hydrosilanes, hydrosilylation using asymmetric, allyl-, NSC-terminated PEO of narrow molecular weight, and covalent modification in one step with amine-containing biological molecules including oligopeptides (YIGSR, RGDS), proteins (EGF, albumin, fibrinogen, mucin), and glycosaminoglycans (heparin). Silicones 33-41 fibrinogen beta chain Homo sapiens 387-397 16417248-2 2006 A generic route to biocompatible silicone elastomers is described involving high yield surface functionalization of standard silicones with hydrosilanes, hydrosilylation using asymmetric, allyl-, NSC-terminated PEO of narrow molecular weight, and covalent modification in one step with amine-containing biological molecules including oligopeptides (YIGSR, RGDS), proteins (EGF, albumin, fibrinogen, mucin), and glycosaminoglycans (heparin). Silicones 33-41 LOC100508689 Homo sapiens 399-404 15909158-8 2005 In contrast, cells grown on PMMA and silicone lenses displayed a spindle-shaped, myofibroblast-like morphology, increased apoptosis, reduced adhesion, and enhanced production of EMT proteins such as fibronectin and type I collagen. Silicones 37-45 fibronectin 1 Homo sapiens 199-210 16217457-4 2005 METHODS: Over a 15-year period, microvascular free flap technique has been used successfully as a surgical tool to correct severe soft-tissue complications of the face resulting from silicone treatment of facial contour deformities. Silicones 183-191 arachidonate 5-lipoxygenase activating protein Homo sapiens 51-55 16217481-9 2005 CONCLUSIONS: The TGF-beta1 inhibitor peptide applied in a matrix with tetraglycerol dipalmitate is significantly effective in achieving a reduction in periprosthetic fibrosis after placement of silicone implants, either subcutaneously or submuscularly. Silicones 194-202 transforming growth factor, beta 1 Rattus norvegicus 17-26 15793830-6 2005 The atelocollagen and silicone tube groups demonstrated fewer c-fos-expressed cells in the spinal cord than the controls. Silicones 22-30 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 62-67 15936131-4 2005 The remarkable number of osteolytic changes seen in the bones adjacent to MCP prostheses in this study would suggest that silastic prostheses should only be used when other surgical alternatives cannot be used and that long-term control by radiography be maintained after implantation of silicone prostheses into the MCP joint. Silicones 288-296 CD46 molecule Homo sapiens 74-77 16111150-9 2005 Microvessels were occluded significantly more often in wounds dressed with the silicone gel, which also diminished the expression of mutant p53, an indirect inhibitor of apoptosis, although greater apoptosis was not confirmed quantitatively by use of TUNEL. Silicones 79-87 tumor protein p53 Equus caballus 140-143 15982392-5 2005 This review proposes polyurethane/silicone breast implants as a potential cause of the condition and highlights the dramatic response to interferon (IFN)-alpha in a woman, so exposed, with widespread disease in the liver and lungs. Silicones 34-42 interferon alpha 1 Homo sapiens 137-159 15371257-3 2005 We describe a method to adhere the synthetic peptides RGD (fibronectin) and YIGSR (laminin) onto silicone for culturing primary cardiac cells and studying responses to mechanical stimulation. Silicones 97-105 fibronectin 1 Homo sapiens 59-70 15657343-8 2005 In vivo, recombinant CR-1 protein induced microvessel formation in Matrigel-filled silicone cylinders, and microvessel formation was statistically significantly inhibited with a blocking anti-CR-1 monoclonal antibody (CR-1 and antibody = 127% of microvessel formation compared with that in untreated control cylinders and CR-1 alone = 259%; difference = 132%, 95% confidence interval [CI] = 123% to 140%; P<.001). Silicones 83-91 teratocarcinoma-derived growth factor 1 Mus musculus 21-25 16032724-7 2005 After 90 days, light microscopy in group B demonstrated that STX-transduced SCs with increased motility ensured nerve regeneration, through silicone tubes, in all cases. Silicones 140-148 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Rattus norvegicus 61-64 16019731-2 2005 In compressed nerves (application of a narrow silicone tube), ATF3 immunoreactivity was seen in the nucleus of sensory neurons and in Schwann cells below the compression at two and four weeks. Silicones 46-54 activating transcription factor 3 Rattus norvegicus 62-66 15774111-9 2005 There were some macrophages marker (CD68) positive staining cells in the tissues filled with silicone bubbles, such as preretinal or subretinal membrane and optic nerve. Silicones 93-101 CD68 molecule Homo sapiens 36-40 20587254-9 2004 Exp 1) When the crevice appeared between GuardWire balloon and silicone tube, simulated debris began to concentrate just below the balloon. Silicones 63-71 exportin 1 Homo sapiens 0-5 15657666-2 2004 This prospective study evaluates the medium-term clinical effects of an injectable silicone biomaterial, PTP (Bioplastique), used to augment the internal anal sphincter. Silicones 83-91 protein tyrosine phosphatase receptor type U Homo sapiens 105-108 15475839-2 2004 Considering that angiotensin II (Ang II) plays an important role in cardiovascular physiology and pathology and that cardiovascular disease increases in postmenopausal women, the aim of this study was to investigate whether the Ang II contractile response in ovariectomized rat carotid artery is modified after a vascular injury by silicone collar. Silicones 332-340 angiotensinogen Homo sapiens 228-234 15476262-8 2004 In addition, mannose receptor (MR) expression was up-regulated on the silicone-modified polyurethanes and PDMS control in the presence of IL-4. Silicones 70-78 mannose receptor C-type 1 Homo sapiens 13-29 15476262-8 2004 In addition, mannose receptor (MR) expression was up-regulated on the silicone-modified polyurethanes and PDMS control in the presence of IL-4. Silicones 70-78 interleukin 4 Homo sapiens 138-142 15732865-6 2004 The warm silicone rubber bristles resulted in a higher density of PCNA-positive fibroblasts compared with the cooler silicone rubber bristle. Silicones 9-17 proliferating cell nuclear antigen Canis lupus familiaris 66-70 15732865-7 2004 The number of PCNA-positive basal cells in the junctional epithelium also increased following electric toothbrushing with warmed silicone rubber bristles. Silicones 129-137 proliferating cell nuclear antigen Canis lupus familiaris 14-18 15363633-4 2004 When cyclic strain was applied to chick embryo fibroblasts cultured on silicone membranes, tenascin-C mRNA and protein levels were increased twofold within 6 h compared to the resting control. Silicones 71-79 tenascin C Gallus gallus 91-101 15460057-0 2004 [Expression of nerve growth factor mRNA and nerve regeneration after discontinuous injection of phorbol-12-myristate-13-acetate into silicone chamber]. Silicones 133-141 nerve growth factor Rattus norvegicus 15-34 15190843-6 2004 The patient was informed that a wide excision of the lip was necessary, and then she confessed she underwent silicone injections in the past. Silicones 109-117 SMG1 nonsense mediated mRNA decay associated PI3K related kinase Homo sapiens 53-56 15236756-6 2004 The capsule/silicone implant contact zone was consistently characterized by a palisade-like single or multilayered cell accumulation consisting of HSP60+ macrophages and HSP60+ fibroblasts. Silicones 12-20 heat shock protein family D (Hsp60) member 1 Homo sapiens 147-152 15236756-6 2004 The capsule/silicone implant contact zone was consistently characterized by a palisade-like single or multilayered cell accumulation consisting of HSP60+ macrophages and HSP60+ fibroblasts. Silicones 12-20 heat shock protein family D (Hsp60) member 1 Homo sapiens 170-175 15190843-7 2004 This is a case of a granulomatous reaction after silicone injection in the lip. Silicones 49-57 SMG1 nonsense mediated mRNA decay associated PI3K related kinase Homo sapiens 75-78 15078494-1 2004 We report the case of a 32-year-old woman who underwent silicone injection into the upper lip 2 years prior to presenting with masses clinically suspicious for tumor and interpreted on biopsy as low-grade liposarcoma. Silicones 56-64 annexin A2 pseudogene 3 Homo sapiens 90-95 14665434-5 2004 Immortalized mouse podocytes grown on flexible silicone membranes were cyclically stretched (5% elongation, 0.5 Hz) for 2 h. EP4 and COX-2 mRNA increased three- and sevenfold above nonstretched controls, whereas EP1 and COX-1 levels were unchanged. Silicones 47-55 prostaglandin E receptor 4 (subtype EP4) Mus musculus 125-128 15264659-7 2004 In contrast, when exposed to IL-4, a cytokine known to induce FBGC formation, silicone modification resulted in more macrophage fusion to form foreign body giant cells. Silicones 78-86 interleukin 4 Homo sapiens 29-33 15023795-9 2004 CONCLUSIONS: These results suggest that silicone gel is responsible for increased bFGF levels in normal and fetal dermal fibroblasts. Silicones 40-48 fibroblast growth factor 2 Homo sapiens 82-86 15023795-0 2004 The effect of silicone gel on basic fibroblast growth factor levels in fibroblast cell culture. Silicones 14-22 fibroblast growth factor 2 Homo sapiens 30-60 15023795-3 2004 OBJECTIVE: To investigate whether the presence of silicone alters the secretion of basic fibroblast growth factor (bFGF), a key cytokine involved in the scar formation process. Silicones 50-58 fibroblast growth factor 2 Homo sapiens 83-113 15023795-3 2004 OBJECTIVE: To investigate whether the presence of silicone alters the secretion of basic fibroblast growth factor (bFGF), a key cytokine involved in the scar formation process. Silicones 50-58 fibroblast growth factor 2 Homo sapiens 115-119 15023795-10 2004 We postulate that silicone gel treats and prevents hypertrophic scar tissue, which contains histologically normal fibroblasts, by modulating expression of growth factors such as bFGF. Silicones 18-26 fibroblast growth factor 2 Homo sapiens 178-182 15050078-1 2004 This paper describes the development of an abscess after injection of an alloplastic preparation (silicone) for enhancement of the lower lip. Silicones 98-106 SMG1 nonsense mediated mRNA decay associated PI3K related kinase Homo sapiens 137-140 15200277-9 2004 CD 68-positive macrophages were found in the silicone-filled vacuoles. Silicones 45-53 CD68 molecule Homo sapiens 0-5 14576525-1 2003 PURPOSE: The structure of mucin balls collected from silicone hydrogel contact lens wearers was examined to determine their nature. Silicones 53-61 LOC100508689 Homo sapiens 26-31 12889010-10 2003 Titanium dioxide-coated silicone inhibited IL-6 production by 77% compared to uncoated silicone. Silicones 24-32 interleukin 6 Homo sapiens 43-47 14634910-0 2003 Enhancement of rat sciatic nerve regeneration by fibronectin and laminin through a silicone chamber. Silicones 83-91 fibronectin 1 Rattus norvegicus 49-60 12604645-4 2003 Endothelin-1 was able to distort and reduce the wrinkles in the silicone surface. Silicones 64-72 endothelin 1 Homo sapiens 0-12 12699678-3 2003 NGF-containing polymeric microspheres fabricated from a biodegradable poly(phosphoester) (PPE) polymer were loaded into silicone or PPE conduits to provide for prolonged, site-specific delivery of NGF. Silicones 120-128 nerve growth factor Homo sapiens 0-3 12699678-5 2003 Three months after implantation, morphological analysis revealed higher values of fiber diameter, fiber population and fiber density and lower G-ratio at the distal end of regenerated nerve cables collected from NGF microsphere-loaded silicone conduits, as compared with those from control conduits loaded with either saline alone, BSA microspheres, or NGF protein without microencapsulation. Silicones 235-243 nerve growth factor Homo sapiens 212-215 12746887-8 2003 E-selectin expression was unchanged for culturing ECs on coated PET, PP, and PTFE and reduced for polyurethane and silicone. Silicones 115-123 selectin E Homo sapiens 0-10 12682816-0 2003 Rifampin-impregnated silicone catheters: a potential tool for prevention and treatment of CSF shunt infections. Silicones 21-29 colony stimulating factor 2 Homo sapiens 90-93 12692485-0 2003 Mucin balls with wear of conventional and silicone hydrogel contact lenses. Silicones 42-50 LOC100508689 Homo sapiens 0-5 12692485-4 2003 RESULTS: Subjects in the silicone hydrogel group had significantly greater numbers of mucin balls compared with subjects in the conventional hydrogel group over time (p < 0.001), but there were no significant differences in the percentage of subjects with mucin balls between the two groups. Silicones 25-33 LOC100508689 Homo sapiens 86-91 12547720-7 2003 A significant reduction in capsular vascular density was also associated with the silicone implants in the SPARC-null animals. Silicones 82-90 secreted acidic cysteine rich glycoprotein Mus musculus 107-112 12661663-1 2003 The paper investigates the conformational stability of bovine serum albumin (BSA) and fibrinogen during 24-h incubation in turn with a linear silicone polymer (polydimethylsiloxane (PDMS)), with linear silicone oligomers (hexamethyldisiloxane and octamethyltrisiloxane) and with cyclic silicone oligomers (octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5)). Silicones 142-150 fibrinogen beta chain Homo sapiens 86-96 12661663-1 2003 The paper investigates the conformational stability of bovine serum albumin (BSA) and fibrinogen during 24-h incubation in turn with a linear silicone polymer (polydimethylsiloxane (PDMS)), with linear silicone oligomers (hexamethyldisiloxane and octamethyltrisiloxane) and with cyclic silicone oligomers (octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5)). Silicones 202-210 albumin Homo sapiens 62-81 12661663-1 2003 The paper investigates the conformational stability of bovine serum albumin (BSA) and fibrinogen during 24-h incubation in turn with a linear silicone polymer (polydimethylsiloxane (PDMS)), with linear silicone oligomers (hexamethyldisiloxane and octamethyltrisiloxane) and with cyclic silicone oligomers (octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5)). Silicones 202-210 albumin Homo sapiens 62-81 12551682-7 2003 Significantly more vitronectin was bound to the 2 silicone IOLs than to any other IOL (P <.01 to.0001) at 7 days. Silicones 50-58 vitronectin Homo sapiens 19-30 14533856-3 2003 This study shows a material-dependent increase of hsp70 levels in plasma following contact of fresh heparinized whole human blood with three different biomaterials (PVC, heparin-coated PVC, Silicone). Silicones 190-198 heat shock protein family A (Hsp70) member 4 Homo sapiens 50-55 12527344-9 2002 Laparoscopic adjustable gastric banding with the LAP-BAND system (INAMED Health, Santa Barbara, CA), a restrictive procedure involving placement of a silicone band around the upper stomach, was introduced in the early 1990s and approved by the US Food and Drug Administration for use in the United States in June 2001. Silicones 150-158 LAP Homo sapiens 49-52 15013282-0 2003 Antithrombin activity of lepirudin adsorbed to silicone (polydimethylsiloxane) tubing. Silicones 47-55 serpin family C member 1 Homo sapiens 0-12 12487399-0 2002 Ginsenoside Rb1 enhances peripheral nerve regeneration across wide gaps in silicone rubber chambers. Silicones 75-83 RB transcriptional corepressor 1 Rattus norvegicus 12-15 12772451-4 2002 CNTF or saline were injected into silicone chambers during nerve repair and injected subcutaneously every day after surgery in group A and B respectively. Silicones 34-42 ciliary neurotrophic factor Canis lupus familiaris 0-4 12394542-1 2002 PURPOSE: Mucin balls appear to cause spherical indentations in the corneal epithelium during silicone hydrogel extended contact lens wear. Silicones 93-101 LOC100508689 Homo sapiens 9-14 12106739-4 2002 RESULTS: The analysis yielded the correction factors for pseudophakic axial length measurements for Sensar acrylic and SLM-2 silicone (Allergan) IOLs. Silicones 125-133 KH RNA binding domain containing, signal transduction associated 3 Homo sapiens 119-124 12227447-10 2002 Only the master blue pigment (PS-4) recorded a higher delta E, 6.26 at 50 degrees C. At a moderate temperature of 35 degrees C, both pigmented and clear silicone test samples remained relatively colourfast. Silicones 153-161 taste 2 receptor member 18 pseudogene Homo sapiens 30-34 12095418-7 2002 Besides, cell activation was still evident 45 days after the silicone injection: activated macrophages exhibited an increased expression of adhesion (CD54 and CD44) and co-stimulatory molecules (CD86) and an enhanced production of oxidant metabolites and NO. Silicones 61-69 intercellular adhesion molecule 1 Homo sapiens 150-154 12095418-7 2002 Besides, cell activation was still evident 45 days after the silicone injection: activated macrophages exhibited an increased expression of adhesion (CD54 and CD44) and co-stimulatory molecules (CD86) and an enhanced production of oxidant metabolites and NO. Silicones 61-69 CD44 molecule (Indian blood group) Homo sapiens 159-163 12095418-7 2002 Besides, cell activation was still evident 45 days after the silicone injection: activated macrophages exhibited an increased expression of adhesion (CD54 and CD44) and co-stimulatory molecules (CD86) and an enhanced production of oxidant metabolites and NO. Silicones 61-69 CD86 molecule Homo sapiens 195-199 12134987-3 2002 A silicone tube was inserted after identifying the causes of prior probing failures by observing the probing tip directly with intranasal endoscopy. Silicones 2-10 TOR signaling pathway regulator Homo sapiens 109-112 11862035-0 2002 Expression of cyclooxygenase-2 in the periprosthetic capsule surrounding a silicone shell implant in the rat. Silicones 75-83 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 14-30 11962609-0 2002 Quantification of fibronectin adsorption to silicone-rubber cell culture substrates. Silicones 44-52 fibronectin 1 Homo sapiens 18-29 11862035-3 2002 To characterize further the nature of the inflammatory response to silicone breast implants, the authors evaluated the expression of the enzyme cyclooxygenase-2 (COX-2) by the tissues and cells of the breast capsule after silicone augmentation in an animal model. Silicones 222-230 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 144-160 11862035-3 2002 To characterize further the nature of the inflammatory response to silicone breast implants, the authors evaluated the expression of the enzyme cyclooxygenase-2 (COX-2) by the tissues and cells of the breast capsule after silicone augmentation in an animal model. Silicones 222-230 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 162-167 11849074-1 2002 Penta- and hexa-coordinated silicon is rare, occurring as a transient species in some glasses, nonaqueous organosilicon solutions and organosilicon gels such as silicone, and is stable at high pressures within the earth in dense phases such as stishovite. Silicones 161-169 hexosaminidase subunit alpha Homo sapiens 11-15 11712992-0 2001 Bioavailability of octamethylcyclotetrasiloxane (D(4)) after exposure to silicones by inhalation and implantation. Silicones 73-82 Rho GDP dissociation inhibitor beta Homo sapiens 48-53 12614010-0 2002 An evaluation of mucin balls associated with high-DK silicone-hydrogel contact lens wear. Silicones 53-61 LOC100508689 Homo sapiens 17-22 11820163-5 2001 Screwed to the end of the pin is a conical metal adapter to which is attached a silicone cylinder whose right-angled distal end is located subcutaneously and ends in a titanium mesh. Silicones 80-88 dynein light chain LC8-type 1 Homo sapiens 26-29 11740663-13 2001 Bed isolation with a silicone sheet is suggested for use in the study of rat skin-flap survival. Silicones 21-29 arachidonate 5-lipoxygenase activating protein Rattus norvegicus 82-86 11718411-2 2001 METHOD: In an initial laboratory validation test, a silicone AAA model was imaged with a stereo-pair configuration of calibrated digital cameras using retro-reflective and ink dot surface targets. Silicones 52-60 AAA1 Homo sapiens 61-64 11697401-9 2001 In spite of the normal VCU, we offered these patients endoscopic treatment of VUR by submeatal injection of Teflon or microparticulate silicone (Macroplastic). Silicones 135-143 VUR Homo sapiens 78-81 11274806-0 2001 ATR-FTIR spectroscopic investigations on the effect of solvents on the permeation of benzoic acid and salicylic acid through silicone membranes. Silicones 125-133 ATR serine/threonine kinase Homo sapiens 0-3 11525366-1 2001 Intragastric prosthesis (Lap-Band, BioEnterics Co., Carpinteria, CA, U.S.A.) migration is one of the major long-term complications of laparoscopic adjustable silicone gastric banding. Silicones 158-166 LAP Homo sapiens 25-28 11288105-3 2001 The transport of LAP across silicone membrane from donor solutions containing the drug at different degrees of saturation (DS = 1-5) was evaluated by two independent experimental methods: (i) using attenuated total-reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and (ii) using standard vertical diffusion cells followed by quantification with high-performance liquid chromatography (HPLC). Silicones 28-36 LAP Homo sapiens 17-20 11361228-1 2001 OBJECTIVE: To assess whether breast implant rupture or extracapsular silicone are associated with selected symptoms of self-reported physician-diagnosed connective tissue disease (CTD). Silicones 69-77 CTD Homo sapiens 180-183 11361228-5 2001 Women with extracapsular silicone (silicone gel outside of the fibrous scar that forms around breast implants) were more likely to report having fibromyalgia (FM, p = 0.004) or other CTD, which included dermatomyositis, polymyositis, Hashimoto"s thyroiditis, mixed CTD, pulmonary fibrosis, eosinophilic fasciitis, and polymyalgia (p = 0.008) than other women in the study. Silicones 25-33 CTD Homo sapiens 183-186 11361228-5 2001 Women with extracapsular silicone (silicone gel outside of the fibrous scar that forms around breast implants) were more likely to report having fibromyalgia (FM, p = 0.004) or other CTD, which included dermatomyositis, polymyositis, Hashimoto"s thyroiditis, mixed CTD, pulmonary fibrosis, eosinophilic fasciitis, and polymyalgia (p = 0.008) than other women in the study. Silicones 25-33 CTD Homo sapiens 265-268 11361228-5 2001 Women with extracapsular silicone (silicone gel outside of the fibrous scar that forms around breast implants) were more likely to report having fibromyalgia (FM, p = 0.004) or other CTD, which included dermatomyositis, polymyositis, Hashimoto"s thyroiditis, mixed CTD, pulmonary fibrosis, eosinophilic fasciitis, and polymyalgia (p = 0.008) than other women in the study. Silicones 35-43 CTD Homo sapiens 183-186 11331446-1 2001 BACKGROUND: Ion implantation of silicone vascular catheters has been shown in preclinical and pilot studies to alter the thrombogenicity of silicone surfaces through the reduced adherence of thrombin. Silicones 32-40 coagulation factor II, thrombin Homo sapiens 191-199 11331446-1 2001 BACKGROUND: Ion implantation of silicone vascular catheters has been shown in preclinical and pilot studies to alter the thrombogenicity of silicone surfaces through the reduced adherence of thrombin. Silicones 140-148 coagulation factor II, thrombin Homo sapiens 191-199 11242902-0 2001 [Silicone as a therapeutic aid in the treatment of hypertrophic scars and keloids]. Silicones 1-9 activation induced cytidine deaminase Homo sapiens 27-30 11161519-12 2001 We assumed that the W/O silicone emulsions were stabilized by the efficient orientation of the aggregates in the interface between the silicone phase and the water phase by using PSM as a cosurfactant. Silicones 24-32 folate hydrolase 1B (pseudogene) Homo sapiens 179-182 11161519-12 2001 We assumed that the W/O silicone emulsions were stabilized by the efficient orientation of the aggregates in the interface between the silicone phase and the water phase by using PSM as a cosurfactant. Silicones 135-143 folate hydrolase 1B (pseudogene) Homo sapiens 179-182 15348314-6 2001 Monocytes/macrophages on polyurethane and teflon, and those on silicone only in long culture-time produced high GM-CSF amounts, where as those on TCPS exhibited low levels of GM-CSF. Silicones 63-71 colony stimulating factor 2 Homo sapiens 112-118 15348314-6 2001 Monocytes/macrophages on polyurethane and teflon, and those on silicone only in long culture-time produced high GM-CSF amounts, where as those on TCPS exhibited low levels of GM-CSF. Silicones 63-71 colony stimulating factor 2 Homo sapiens 175-181 15348314-8 2001 Accordingly, CLSM-analysis revealed low nuclear NF-kappaB in cells on TCPS and high nuclear NF-kappaB in mature macrophages on silicone and polyurethane, showing a high cellular activation on the latter two polymers. Silicones 127-135 nuclear factor kappa B subunit 1 Homo sapiens 92-101 15348316-0 2001 Functionalization of silicone rubber for the covalent immobilization of fibronectin. Silicones 21-29 fibronectin 1 Homo sapiens 72-83 12678127-0 2001 Silicone sheeting decreases fibroblast activity and downregulates TGFbeta2 in hypertrophic scar model. Silicones 0-8 transforming growth factor beta 2 Homo sapiens 66-74 12678127-12 2001 The immunoassay for TGFbeta2 showed a statistically significant decrease with all four types of silicone sheeting. Silicones 96-104 transforming growth factor beta 2 Homo sapiens 20-28 12678127-14 2001 In addition, TGFbeta2 is downregulated in the silicone exposed group. Silicones 46-54 transforming growth factor beta 2 Homo sapiens 13-21 15348372-6 2001 Catheter lubricity was quantified, using a Texture Analyzer, by measurement of the forces required for insertion and removal of the device from two model substrates, agar and mucin-coated silicone tubing. Silicones 188-196 LOC100508689 Homo sapiens 175-180 11197533-3 2000 The aim of this study was to assess whether vascular endothelial growth factor (VEGF), a highly specific endothelial cell mitogen, can enhance vascularisation and, indirectly, axonal regeneration within a silicone nerve regeneration chamber. Silicones 205-213 vascular endothelial growth factor A Rattus norvegicus 44-78 11147677-5 2000 The increased vascular density seen in skin of TSP2-null mice can be reproduced in a number of models of injury, including subcutaneous implantation of polyvinyl alcohol sponges and silicone rubber discs, and excisional skin wounds. Silicones 182-190 thrombospondin 2 Mus musculus 47-51 11197533-3 2000 The aim of this study was to assess whether vascular endothelial growth factor (VEGF), a highly specific endothelial cell mitogen, can enhance vascularisation and, indirectly, axonal regeneration within a silicone nerve regeneration chamber. Silicones 205-213 vascular endothelial growth factor A Rattus norvegicus 80-84 10919692-3 2000 A novel culture system using a fibronectin-coated silicone surface was employed to evaluate the orientation of human gingival fibroblasts around titanium discs. Silicones 50-58 fibronectin 1 Homo sapiens 31-42 11203664-1 2000 PURPOSE: The purpose of the present study was to evaluate some important mechanical properties of an experimental silicone material (PM1) to assess its potential as a mouthguard material. Silicones 114-122 transmembrane protein 11 Homo sapiens 133-136 10849472-7 2000 Transfection of the gene for VEGF resulted in inhibition or regression of intimal hyperplasia induced by the silicone collar in the rabbit. Silicones 109-117 vascular endothelial growth factor A Oryctolagus cuniculus 29-33 10882054-0 2000 Restricted and shared patterns of TCR beta-chain gene expression in silicone breast implant capsules and remote sites of tissue inflammation. Silicones 68-76 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 34-42 10649156-2 2000 STUDY DESIGN: WISH cells, a human amniotic epithelial cell line, were grown on silicone elastomer sheets coated with extracellular matrix and reproducibly distended by 40% in a novel device for 4 hours. Silicones 79-87 NCK interacting protein with SH3 domain Homo sapiens 14-18 10799447-9 2000 Furthermore, peritoneal macrophages from silicone- and pristane-treated mice produced higher levels of interleukin-1beta (IL-1beta) and IL-6 than those from PBS-treated mice after lipopolysaccharide stimulation. Silicones 41-49 interleukin 1 beta Mus musculus 103-120 10799447-9 2000 Furthermore, peritoneal macrophages from silicone- and pristane-treated mice produced higher levels of interleukin-1beta (IL-1beta) and IL-6 than those from PBS-treated mice after lipopolysaccharide stimulation. Silicones 41-49 interleukin 1 beta Mus musculus 122-130 10799447-9 2000 Furthermore, peritoneal macrophages from silicone- and pristane-treated mice produced higher levels of interleukin-1beta (IL-1beta) and IL-6 than those from PBS-treated mice after lipopolysaccharide stimulation. Silicones 41-49 interleukin 6 Mus musculus 136-140 10863416-0 1999 The influence of exogenous nerve growth factor on inferior alveolar nerve regeneration in silicone tubes. Silicones 90-98 beta-nerve growth factor Oryctolagus cuniculus 27-46 10663910-2 2000 When cardiomyocytes cultured on silicone dishes were stretched, second messengers such as protein kinase C (PKC), Raf-1 kinase, and mitogen-activated protein (MAP) kinases were activated, which were followed by increased protein synthesis. Silicones 32-40 Raf-1 proto-oncogene, serine/threonine kinase Rattus norvegicus 114-119 10863416-1 1999 OBJECTIVE: To explore the effects of exogenous nerve growth factor (NGF) in the regeneration of adult white rabbit inferior alveolar nerves within silicone tubes. Silicones 147-155 beta-nerve growth factor Oryctolagus cuniculus 47-66 10863416-1 1999 OBJECTIVE: To explore the effects of exogenous nerve growth factor (NGF) in the regeneration of adult white rabbit inferior alveolar nerves within silicone tubes. Silicones 147-155 beta-nerve growth factor Oryctolagus cuniculus 68-71 10456700-12 1999 CONCLUSIONS: These results indicate that malfunctions can be minimized in silicone venous access catheters by locating the catheter tip as close to the superior vena cava/right atrial junction as possible, or slightly inside the right atrium. Silicones 74-82 TOR signaling pathway regulator Homo sapiens 132-135 10638141-2 1999 The IFN-loaded silicone formulation (IFN-SF) is a sustained-release formulation of human lymphoblastoid IFN, with a medical grade silicone elastomer used as the carrier material. Silicones 15-23 interferon alpha 1 Homo sapiens 4-7 10638141-2 1999 The IFN-loaded silicone formulation (IFN-SF) is a sustained-release formulation of human lymphoblastoid IFN, with a medical grade silicone elastomer used as the carrier material. Silicones 15-23 interferon alpha 1 Homo sapiens 37-40 10638141-2 1999 The IFN-loaded silicone formulation (IFN-SF) is a sustained-release formulation of human lymphoblastoid IFN, with a medical grade silicone elastomer used as the carrier material. Silicones 15-23 interferon alpha 1 Homo sapiens 37-40 10638141-2 1999 The IFN-loaded silicone formulation (IFN-SF) is a sustained-release formulation of human lymphoblastoid IFN, with a medical grade silicone elastomer used as the carrier material. Silicones 130-138 interferon alpha 1 Homo sapiens 4-7 10515822-4 1999 Chemotaxis (3 h) in response to (10-7 mL) FMLP, zymosan-activated serum, and fresh serum (100%) was greater on silicone than on PU (P<.05). Silicones 111-119 formyl peptide receptor 1 Homo sapiens 42-46 10515822-6 1999 Serum in the PMNL well significantly decreased chemotaxis toward FMLP on silicone (P<.05) but not on PU. Silicones 73-81 formyl peptide receptor 1 Homo sapiens 65-69 10558602-3 1999 The Food and Drug Administration (FDA) is issuing a final rule to require the filing of a premarket approval application (PMA) or a notice of completion of a product development protocol (PDP) for the silicone inflatable breast prosthesis, a generic type of medical device intended to augment or reconstruct the female breast. Silicones 201-209 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 188-191 10558602-5 1999 Commercial distribution of this device must cease unless a manufacturer or importer has filed with FDA a PMA or PDP for its version of the silicone inflatable breast prosthesis within 90 days of the effective date of this regulation. Silicones 139-147 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 112-115 10434070-0 1999 Cell adhesion to textured silicone surfaces: the influence of time of adhesion and texture on focal contact and fibronectin fibril formation. Silicones 26-34 fibronectin 1 Homo sapiens 112-123 11776909-0 1999 [The influence of nerve growth factor on inferior alveolar nerves regeneration in the silicone tubes]. Silicones 86-94 beta-nerve growth factor Oryctolagus cuniculus 18-37 11776909-1 1999 OBJECTIVE: To explore the effect of exogenous nerve growth factor(NGF) in the regeneration of adult white rabbits inferior alveolar nerve within the silicone tubes. Silicones 149-157 beta-nerve growth factor Oryctolagus cuniculus 46-65 10434070-3 1999 In this study we determined the formation of focal adhesions and fibronectin fibrillar structures by human fibroblasts and human umbilical vein endothelial cells adhered to fibronectin-precoated, smooth, and textured silicones as a function of time. Silicones 217-226 fibronectin 1 Homo sapiens 65-76 9810992-0 1998 The use of silicone occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation. Silicones 11-19 STIL centriolar assembly protein Homo sapiens 40-43 10355404-7 1999 CONCLUSIONS: Silicone coating over a microporous hollow-fiber membrane may improve biocompatibility by reducing C3a activation. Silicones 13-21 complement C3 Homo sapiens 112-115 10327156-4 1999 MCAO was accomplished by an insertion of nylon thread with silicone coating for 24 h. Application of anti-P-selectin antibody significantly reduced infarct size and brain water content at 24 h of MCAO. Silicones 59-67 selectin P Rattus norvegicus 106-116 9915580-7 1999 When anti-integrin beta1 antibody was added to live cardiomyocytes grown on the silicone rubber substratum, the transmission of contraction forces was inhibited. Silicones 80-88 integrin subunit beta 1 Rattus norvegicus 10-24 10591132-7 1999 When these in vitro data were collectively evaluated, the coating that most effectively passivated silicone rubber was the polypeptide derived from elastin. Silicones 99-107 elastin Homo sapiens 148-155 9918243-18 1999 Comparison of autoantibody incidence in asymptomatic and symptomatic women with silicone breast implants revealed an increased incidence of anti-SSB/La and anticollagen II in both groups. Silicones 80-88 small RNA binding exonuclease protection factor La Homo sapiens 145-148 9756070-3 1998 MATERIALS AND METHODS: A life-sized AAA model was constructed of silicone elastomers with luminal access ports for introduction of contrast media and catheters. Silicones 65-73 AAA1 Homo sapiens 36-39 9755918-1 1998 The appearance of fistulas and the posterior intragastric inclusion of the adjustable silicone Lap-Band prothesis have been described, representing a severe complication of the Lap-Band procedure. Silicones 86-94 LAP Homo sapiens 95-98 9874287-1 1998 The short-term effects of silicone particles on the ability of splenic and peritoneal macrophages to produce Interleukin-1 (IL-1) were assessed. Silicones 26-34 interleukin 1 complex Mus musculus 124-128 9755918-1 1998 The appearance of fistulas and the posterior intragastric inclusion of the adjustable silicone Lap-Band prothesis have been described, representing a severe complication of the Lap-Band procedure. Silicones 86-94 LAP Homo sapiens 177-180 9685131-4 1998 Test catheters had a silicone-encased stainless steel loop at the indwelling end that contacted the vein wall and stabilized the catheter tip in the center of the vessel. Silicones 21-29 TOR signaling pathway regulator Homo sapiens 138-141 9509339-6 1998 Cells proliferated on the fibronectin-preadsorbed silicone, as demonstrated by increased coverage and occurrence of subpopulations in the S and G2/M phase of the cell cycle. Silicones 50-58 fibronectin 1 Homo sapiens 26-37 9509339-12 1998 Fibronectin preadsorption of silicone only resulted in slightly higher MTT conversion. Silicones 29-37 fibronectin 1 Homo sapiens 0-11 9676177-10 1998 We report the case of an adult female patient with silicone breast implantation for bilateral mastectomy (performed 12 months before) and a unique syndrome characterized by low-grade fever, chronic fatigue, arthralgias of the hands, dysphagia, dry eye, increased level of rheumatoid factor and decreased value of complement C3 and C4. Silicones 51-59 complement C3 Homo sapiens 313-326 9359398-8 1997 The pattern of motile behaviour is characteristic of myosin on silicone-treated glass and different from the behaviour on nitrocellulose-coated glass. Silicones 63-71 myosin heavy chain 14 Homo sapiens 53-59 9562487-0 1998 Two years of practice in adjustable silicone gastric banding (LAP-BAND): evaluation of variations of body mass index, percentage ideal body weight and percentage excess body weight. Silicones 36-44 LAP Homo sapiens 62-65 9439391-5 1998 Seventeen days after implantation, the number of silicone tubes containing myelinated neuronal regenerates at the mid-tube region was 1 of 6 for thrombin, 6 of 9 for PN-1, and 6 of 10 for saline solution. Silicones 49-57 coagulation factor II Rattus norvegicus 145-153 9291420-6 1997 RESULTS: The frequency and intensity of cellular immune responses against collagen I, collagen III, fibrinogen, and fibronectin were significantly increased in silicone breast implant recipients versus controls. Silicones 160-168 fibronectin 1 Homo sapiens 116-127 9326702-0 1997 Expression of CD44-v6-containing isoform on breast tissue adjacent to silicone breast implants. Silicones 70-78 CD44 molecule (Indian blood group) Homo sapiens 14-18 9360138-8 1997 The optical density at a wavelength of 450 nm for CD42b was 1.47 +/- 0.35 in polypropylene, 1.16 +/- 0.38 in silicone, and 1.85 +/- 0.19 in double polyolefin (p < 0.01 vs silicone) and for CD61 0.98 +/- 0.39 in polypropylene, 0.91 +/- 0.22 in silicone, and 1.69 +/- 0.25 in double polyolefin (p < 0.01 vs silicone and polypropylene). Silicones 109-117 glycoprotein Ib platelet subunit alpha Homo sapiens 50-55 9360138-8 1997 The optical density at a wavelength of 450 nm for CD42b was 1.47 +/- 0.35 in polypropylene, 1.16 +/- 0.38 in silicone, and 1.85 +/- 0.19 in double polyolefin (p < 0.01 vs silicone) and for CD61 0.98 +/- 0.39 in polypropylene, 0.91 +/- 0.22 in silicone, and 1.69 +/- 0.25 in double polyolefin (p < 0.01 vs silicone and polypropylene). Silicones 174-182 glycoprotein Ib platelet subunit alpha Homo sapiens 50-55 9360138-8 1997 The optical density at a wavelength of 450 nm for CD42b was 1.47 +/- 0.35 in polypropylene, 1.16 +/- 0.38 in silicone, and 1.85 +/- 0.19 in double polyolefin (p < 0.01 vs silicone) and for CD61 0.98 +/- 0.39 in polypropylene, 0.91 +/- 0.22 in silicone, and 1.69 +/- 0.25 in double polyolefin (p < 0.01 vs silicone and polypropylene). Silicones 174-182 glycoprotein Ib platelet subunit alpha Homo sapiens 50-55 9360138-8 1997 The optical density at a wavelength of 450 nm for CD42b was 1.47 +/- 0.35 in polypropylene, 1.16 +/- 0.38 in silicone, and 1.85 +/- 0.19 in double polyolefin (p < 0.01 vs silicone) and for CD61 0.98 +/- 0.39 in polypropylene, 0.91 +/- 0.22 in silicone, and 1.69 +/- 0.25 in double polyolefin (p < 0.01 vs silicone and polypropylene). Silicones 174-182 glycoprotein Ib platelet subunit alpha Homo sapiens 50-55 9292814-1 1997 We describe 2 HLA-identical sisters who both received silicone breast implants and subsequently developed polyarticular arthritis and neurologic symptoms. Silicones 54-62 major histocompatibility complex, class II, DR beta 1 Homo sapiens 14-17 9292814-2 1997 In both patients, HLA typing revealed 3 alleles typically associated with rheumatic diseases: HLA-DRB1*0405 and HLA-DQB1*0302 (associated with RA), and HLA-DRB4*01 (associated with mixed connective tissue disease and autoimmune reactions in patients with silicone breast implants. Silicones 255-263 major histocompatibility complex, class II, DR beta 1 Homo sapiens 18-21 9730523-0 1997 Laparoscopic adjustable silicone gastric banding (Lap-Band): how to avoid complications. Silicones 24-32 LAP Homo sapiens 0-3 9263552-0 1997 Immediate reaugmentation of the breasts using bilaterally divided TRAM flaps after removing injected silicone gel and granulomas. Silicones 101-109 translocation associated membrane protein 1 Homo sapiens 66-70 9552454-2 1997 Oxytocin (OT) was incorporated into custom coformulations of Carbopol 974P and silicone polymer and the resulting plasma OT concentration versus time profiles determined following patch application. Silicones 79-87 oxytocin Oryctolagus cuniculus 0-8 9263552-1 1997 The authors present eight cases of reconstruction of the breasts using bilaterally divided TRAM flaps after removing the injected silicone gel and granulomas. Silicones 130-138 translocation associated membrane protein 1 Homo sapiens 91-95 9303936-1 1997 The silicone implant controversy wavers between reassuring epidemiological studies and about 300 case reports of patients developing a definite or incomplete/atypical connective tissue disease (CTD) after receiving a silicone gel-filled breast implant (SBI). Silicones 4-12 CTD Homo sapiens 194-197 9303936-1 1997 The silicone implant controversy wavers between reassuring epidemiological studies and about 300 case reports of patients developing a definite or incomplete/atypical connective tissue disease (CTD) after receiving a silicone gel-filled breast implant (SBI). Silicones 217-225 CTD Homo sapiens 194-197 9101451-0 1997 Producing vascularized bone by heterotopic bone induction and guided tissue regeneration: a silicone membrane-isolated latissimus dorsi island flap in a rat model. Silicones 92-100 arachidonate 5-lipoxygenase activating protein Rattus norvegicus 143-147 9182917-7 1997 Cytokine analysis indicated that tumor necrosis factor alpha levels were lower and interleukin-2 levels were higher in silicone-implanted mice. Silicones 119-127 tumor necrosis factor Mus musculus 33-60 9182917-7 1997 Cytokine analysis indicated that tumor necrosis factor alpha levels were lower and interleukin-2 levels were higher in silicone-implanted mice. Silicones 119-127 interleukin 2 Mus musculus 83-96 9203506-0 1997 Ciliary neurotrophic factor immunoreactivity in rat intramuscular nerve during reinnervation through a silicone tube after severing of the rat sciatic nerve. Silicones 103-111 ciliary neurotrophic factor Rattus norvegicus 0-27 8946235-5 1996 Our results can be summarized as follows: a) Monocytes were stimulated to release inflammatory cytokines like IL-8 and MIP-1 alpha, particularly when silicone was involved; b) Both silicone and polyurethane stimulated thrombocytes thus resulting in the release of P-Selectin and PDGF-AB, although polyurethane was a stronger stimulus; c) Moderate complement activation was triggered by contact with either of the artificial surfaces. Silicones 181-189 C-X-C motif chemokine ligand 8 Homo sapiens 110-114 9000348-16 1997 CONCLUSION: Silicone esophageal stents provide successful short-term palliation for most patients with malignant TEF but are not without associated complications. Silicones 12-20 TEF transcription factor, PAR bZIP family member Homo sapiens 113-116 9186092-1 1997 PURPOSE: To summarize the long-term safety and efficacy, in a large series of patients, of intraocular lenses made from a second-generation silicone material (AMO SLM-2/UV) widely used as an intraocular lens material. Silicones 140-148 KH RNA binding domain containing, signal transduction associated 3 Homo sapiens 163-168 8980470-0 1997 Morphea after silicone gel breast implantation for cosmetic reasons in an HLA-B8, DR3-positive woman. Silicones 14-22 TNF receptor superfamily member 25 Homo sapiens 82-85 8980470-1 1997 We describe an HLA-B8, DR3-positive patient with localized morphea after silicone gel breast implantation for cosmetic reasons. Silicones 73-81 TNF receptor superfamily member 25 Homo sapiens 23-26 8980470-2 1997 We believe that this case suggests that a genetic background, i.e. HLA-B8, DR3 haplotype, is involved in the autoimmune response to silicone. Silicones 132-140 TNF receptor superfamily member 25 Homo sapiens 75-78 9685783-6 1997 CONCLUSIONS: Vitrectomy with silicone oil tamponade is method of choice in the treatment of retinal detachment in the course of PVR. Silicones 29-37 PVR cell adhesion molecule Homo sapiens 128-131 15739448-1 1997 A megabore SCOT series column of silicone OV-101 and OV-17 for the analysis of micro amount of impurities in acrylonitrile is presented. Silicones 33-41 3-oxoacid CoA-transferase 1 Homo sapiens 11-15 9031435-2 1997 The moratorium on silicone gel implants has increased the use of TRAM and free flap breast reconstruction. Silicones 18-26 translocation associated membrane protein 1 Homo sapiens 65-69 8946235-5 1996 Our results can be summarized as follows: a) Monocytes were stimulated to release inflammatory cytokines like IL-8 and MIP-1 alpha, particularly when silicone was involved; b) Both silicone and polyurethane stimulated thrombocytes thus resulting in the release of P-Selectin and PDGF-AB, although polyurethane was a stronger stimulus; c) Moderate complement activation was triggered by contact with either of the artificial surfaces. Silicones 181-189 C-C motif chemokine ligand 3 Homo sapiens 119-130 8946235-5 1996 Our results can be summarized as follows: a) Monocytes were stimulated to release inflammatory cytokines like IL-8 and MIP-1 alpha, particularly when silicone was involved; b) Both silicone and polyurethane stimulated thrombocytes thus resulting in the release of P-Selectin and PDGF-AB, although polyurethane was a stronger stimulus; c) Moderate complement activation was triggered by contact with either of the artificial surfaces. Silicones 181-189 selectin P Homo sapiens 264-274 8864822-4 1996 The purpose of the present study was to determine the effect of silicone on the tight skin (TSK/+) mouse which develops a scleroderma-like syndrome and on its normal pa/pa TSK/- littermate. Silicones 64-72 tsukushi, small leucine rich proteoglycan Mus musculus 92-95 8903457-8 1996 Attachment and growth of vascular wall cells on fibronectin-coated silicone rubber was similar to that obtained on TCP. Silicones 67-75 fibronectin 1 Homo sapiens 48-59 8884011-1 1996 Twenty-six patients with a total of 45 scars were studied to determine the efficacy of the new silicone sheet, Sil-K, in treating hypertrophic scars. Silicones 95-103 STIL centriolar assembly protein Homo sapiens 111-114 8963924-10 1996 Silicone lenses C 10 are easy to handle during implantation and after phacoemulsification satisfactory results are achieved. Silicones 0-8 homeobox C10 Homo sapiens 16-20 8856546-1 1996 Soluble fibronectin and nerve growth factor (NGF) promote axonal regeneration when placed in silicone tubes. Silicones 93-101 fibronectin 1 Homo sapiens 8-19 8856546-1 1996 Soluble fibronectin and nerve growth factor (NGF) promote axonal regeneration when placed in silicone tubes. Silicones 93-101 nerve growth factor Homo sapiens 24-43 8856546-1 1996 Soluble fibronectin and nerve growth factor (NGF) promote axonal regeneration when placed in silicone tubes. Silicones 93-101 nerve growth factor Homo sapiens 45-48 8705664-0 1996 Elevated concentrations of interleukin-1 beta and interleukin-1 receptor antagonist in plasma of women with silicone breast implants. Silicones 108-116 interleukin 1 beta Homo sapiens 27-45 8806060-0 1996 Silicone gel and octamethylcyclotetrasiloxane (D4) enhances antibody production to bovine serum albumin in mice. Silicones 0-8 albumin Mus musculus 90-103 8806060-1 1996 The purpose of the present study was to determine whether components of silicone breast implants [silicon (polydimethylsiloxane) oil, silicone gel, and octamethylcyclotetrasiloxane (D4)] potentiate the antibody response to bovine serum albumin (BSA) in mice. Silicones 72-80 albumin Mus musculus 230-243 8782144-0 1996 Increased urinary NO3(-) + NO2- and neopterin excretion in children breast fed by mothers with silicone breast implants: evidence for macrophage activation. Silicones 95-103 NBL1, DAN family BMP antagonist Homo sapiens 18-21 8628094-3 1996 The BDNF (15 mg/mL) or phosphate buffered saline (control) was injected into the silicone elastomer (Silastic) channel. Silicones 81-89 brain-derived neurotrophic factor Rattus norvegicus 4-8 8738304-2 1996 CCK (1 nM-1 microM) caused concentration-dependent depolarisations when superfused over the nodose ganglion at 37 degrees C as measured by a silicone grease gap technique, and both CCKA antagonists caused significant rightward shifts in the concentration response curve to CCK. Silicones 141-149 cholecystokinin Rattus norvegicus 0-3 8778356-0 1996 Passport system cutting of a chiron C10 UB silicone lens. Silicones 43-51 homeobox C10 Homo sapiens 36-39 9019595-10 1996 Cerclage with silicone band is a method of choice in the majority of RD with PVR grade B and C. Our observations do not confirm the reports of severe complications caused by cerclage, which might be connected with excessive tightening of the band. Silicones 14-22 PVR cell adhesion molecule Homo sapiens 77-80 8596782-2 1996 The need for an additional silicone implant to obtain sufficient breast volume intensified the search for new flaps, resulting in the microvascular TRAM flap, which is currently considered the "gold standard" in autologous breast reconstruction. Silicones 27-35 translocation associated membrane protein 1 Homo sapiens 148-152 8616605-2 1995 Local application of neurotrophin-3 (NT-3) using implanted silicone chambers applied to the proximal transected sciatic nerve stump significantly diminished the transganglionic NPY response in the gracile nucleus and spinal cord but did not affect the CGRP transganglionic response. Silicones 59-67 neurotrophin 3 Rattus norvegicus 21-35 8565552-0 1996 Silicone gel and octamethylcyclotetrasiloxane potentiate antibody production to bovine serum albumin in mice. Silicones 0-8 albumin Rattus norvegicus 87-100 8565552-1 1996 Earlier studies, in the rat, have shown that silicone gel acts as a potent adjuvant for antibody production against bovine serum albumin (BSA). Silicones 45-53 albumin Rattus norvegicus 123-136 8565570-3 1996 To clarify whether silicone enhances development of fibrotic skin lesions and autoantibodies, we tested its effect on tight skin (TSK/+) mice. Silicones 19-27 fibrillin 1 Mus musculus 118-128 8565584-1 1996 Silicone gels derived from commercially obtained implants induce plasmacytomas in 60-70% of highly susceptible BALB/cAn.DBA/2-Idh1-Pep3 congenic mice. Silicones 0-8 isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus 126-130 8565584-1 1996 Silicone gels derived from commercially obtained implants induce plasmacytomas in 60-70% of highly susceptible BALB/cAn.DBA/2-Idh1-Pep3 congenic mice. Silicones 0-8 peptidase C Mus musculus 131-135 8616605-2 1995 Local application of neurotrophin-3 (NT-3) using implanted silicone chambers applied to the proximal transected sciatic nerve stump significantly diminished the transganglionic NPY response in the gracile nucleus and spinal cord but did not affect the CGRP transganglionic response. Silicones 59-67 neurotrophin 3 Rattus norvegicus 37-41 8616605-2 1995 Local application of neurotrophin-3 (NT-3) using implanted silicone chambers applied to the proximal transected sciatic nerve stump significantly diminished the transganglionic NPY response in the gracile nucleus and spinal cord but did not affect the CGRP transganglionic response. Silicones 59-67 neuropeptide Y Rattus norvegicus 177-180 8616605-2 1995 Local application of neurotrophin-3 (NT-3) using implanted silicone chambers applied to the proximal transected sciatic nerve stump significantly diminished the transganglionic NPY response in the gracile nucleus and spinal cord but did not affect the CGRP transganglionic response. Silicones 59-67 calcitonin-related polypeptide alpha Rattus norvegicus 252-256 8534028-0 1995 Comparison of rabbit facial nerve regeneration in nerve growth factor-containing silicone tubes to that in autologous neural grafts. Silicones 81-89 beta-nerve growth factor Oryctolagus cuniculus 50-69 8991984-0 1995 Position 26 of the first domain of the HLA-DQB1 allele in post-silicone implant scleroderma. Silicones 63-71 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 39-47 8991984-7 1995 CONCLUSION: The presence of Gly 26 or Tyr 26 in the HLA-DQB1 first domain in our cases with SSc and silicone implants is consistent with immunogenetic findings reported in Caucasian with idiopathic SSc anticentromere autoantibodies. Silicones 100-108 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 52-60 7586790-0 1995 Skin rash and anti-Ro/SS-A antibodies in an infant from a mother with silicone breast implants. Silicones 70-78 tripartite motif containing 21 Homo sapiens 22-26 8725036-2 1995 We report our experience with the endoscopic treatment of VUR by a submucosal injection of silicone. Silicones 91-99 VUR Homo sapiens 58-61 8523291-3 1995 A CAL is required to avoid potential errors with secondary IOL power predictions; CALs, which are strongly dependent on the material sound speed and less so on lens thickness, ranged from -0.65 mm to -1.20 mm for SLM-1/UV silicone IOLs and from -0.35 mm to -0.55 mm for SLM-2/UV silicone IOLs. Silicones 222-230 carbonic anhydrase 8 Homo sapiens 82-86 8561937-3 1995 A study is therefore presented of the effect of protein content upon the surface tension of CSF and its contact angle to silicone rubber. Silicones 121-129 colony stimulating factor 2 Homo sapiens 92-95 8725036-3 1995 A 24-year-old man who had VUR (Grade II) and renal insufficiency was treated by endoscopic injection of silicone. Silicones 104-112 VUR Homo sapiens 26-29 7654630-4 1995 Monocytes/macrophages incubated on PDMS, silicone rubber and low density polyethylene, LDPE, with or without protein adsorption produced variable levels of IL-1 beta, IL-6 and TNF-alpha dependent on the polymer and adsorbed protein. Silicones 41-49 interleukin 1 beta Homo sapiens 156-165 7760338-4 1995 Passive stretch of cardiomyocytes cultured on silicone membranes activates protein kinase cascades of phosphorylation and induces an increase in protein synthesis and the expression of both immediate early genes such as c-fos, c-myc, c-jun, Egr-1, and late response genes such as beta-myosin heavy chain and skeletal alpha-actin. Silicones 46-54 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 220-225 7760338-4 1995 Passive stretch of cardiomyocytes cultured on silicone membranes activates protein kinase cascades of phosphorylation and induces an increase in protein synthesis and the expression of both immediate early genes such as c-fos, c-myc, c-jun, Egr-1, and late response genes such as beta-myosin heavy chain and skeletal alpha-actin. Silicones 46-54 MYC proto-oncogene, bHLH transcription factor Homo sapiens 227-232 7760338-4 1995 Passive stretch of cardiomyocytes cultured on silicone membranes activates protein kinase cascades of phosphorylation and induces an increase in protein synthesis and the expression of both immediate early genes such as c-fos, c-myc, c-jun, Egr-1, and late response genes such as beta-myosin heavy chain and skeletal alpha-actin. Silicones 46-54 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 234-239 7760338-4 1995 Passive stretch of cardiomyocytes cultured on silicone membranes activates protein kinase cascades of phosphorylation and induces an increase in protein synthesis and the expression of both immediate early genes such as c-fos, c-myc, c-jun, Egr-1, and late response genes such as beta-myosin heavy chain and skeletal alpha-actin. Silicones 46-54 early growth response 1 Homo sapiens 241-246 7988701-1 1994 When hepatic stellate cells (Ito cells, fat-storing cells) were incubated with adrenomedullin, they underwent relaxation as monitored by the silicone-rubber membrane method; 43%, 65% and 87% of stellate cells relaxed 5, 10 and 20 min, respectively, after addition of 10(-6) M adrenomedullin. Silicones 141-149 adrenomedullin Rattus norvegicus 79-93 8061310-4 1994 The loss of motoneurones was further reduced by placing the LIF-containing gelfoam inside a silicone chamber: from 39% to 15% after 7 days, which represented a 62% rescue. Silicones 92-100 LIF, interleukin 6 family cytokine Rattus norvegicus 60-63 7947610-0 1994 Changes in the caldesmon isoform content and intimal thickening in the rabbit carotid artery induced by a silicone elastomer collar. Silicones 106-114 caldesmon Oryctolagus cuniculus 15-24 7533175-14 1994 Similarly human serum albumin antibodies which was significantly higher in patients with silicone implants did not correlate with levels of silicone antibodies. Silicones 89-97 albumin Homo sapiens 16-29 7868190-5 1994 An alteration in the amounts of Schwann cells migrating into the silicone chambers observed after histochemical staining (nChE or GFAP) was supported by biochemical measurements of the nChE activity. Silicones 65-73 glial fibrillary acidic protein Rattus norvegicus 130-134 7996413-8 1994 The speed for an eye with a silicone IOL was found to be 1,476 M/sec (or AL1,532 + 0.04 - 56% of IOL thickness) and for glass, 1,549 M/sec (or AL1,532 + 0.04 + 75% of IOL thickness). Silicones 28-36 ephrin A5 Homo sapiens 73-76 8021954-12 1994 RESULTS: The silicone gels tested induced plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 13-21 V-type proton ATPase subunit E-like Zea mays 87-92 8021954-12 1994 RESULTS: The silicone gels tested induced plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 13-21 isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus 93-97 8021954-12 1994 RESULTS: The silicone gels tested induced plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 13-21 peptidase C Mus musculus 98-102 8021954-17 1994 Silicone gels provide new chemically defined materials that are effective inducers of plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 0-8 V-type proton ATPase subunit E-like Zea mays 131-136 8021954-17 1994 Silicone gels provide new chemically defined materials that are effective inducers of plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 0-8 isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus 137-141 8021954-17 1994 Silicone gels provide new chemically defined materials that are effective inducers of plasmacytomas in BALB/cAnPt-A and BALB/cAnPt.DBA/2-Idh1-Pep3 mice. Silicones 0-8 peptidase C Mus musculus 142-146 7944186-0 1994 Local increase in hyaluronic acid and interleukin-2 in the capsules surrounding silicone breast implants. Silicones 80-88 interleukin 2 Homo sapiens 38-51 8153777-4 1994 Recently, a tube made of silicone rubber and thus resistant to gastric secretions was manufactured for us by the Medical Innovations Corporation of Milpitas, Calif. Silicones 25-33 CCR4-NOT transcription complex subunit 8 Homo sapiens 158-163 8320826-3 1993 Recently, in vitro medel of myocardial stretch on the silicone sheet has demonstrated the up regulation of the "cardiac fetal genes", including beta-MHC, skeletal alpha-actin, and atrial natriuretic factor (ANF), which is known to be a hallmark of the altered gene expression in the hypertrophic heart. Silicones 54-62 major histocompatibility complex, class I, C Homo sapiens 149-152 8087228-8 1994 On the contrary the preliminary results obtained with injection of microparticulate silicone appear very promising: correction of VUR in over 90% of cases and good local tolerance adding to absence of carcinogenic and migration risks. Silicones 84-92 VUR Homo sapiens 130-133 8087228-9 1994 Further trials and a longer evaluation period are necessary before to consider microparticulate silicone as the ideal product to be used in the endoscopic treatment of VUR. Silicones 96-104 VUR Homo sapiens 168-171 8120343-2 1994 CCK-8S caused concentration-dependent depolarizations when superfused over the rat isolated nodose ganglion at 37 degrees C as measured by a silicone grease gap technique. Silicones 141-149 cholecystokinin Rattus norvegicus 0-3 8320826-3 1993 Recently, in vitro medel of myocardial stretch on the silicone sheet has demonstrated the up regulation of the "cardiac fetal genes", including beta-MHC, skeletal alpha-actin, and atrial natriuretic factor (ANF), which is known to be a hallmark of the altered gene expression in the hypertrophic heart. Silicones 54-62 natriuretic peptide A Homo sapiens 180-205 8320826-3 1993 Recently, in vitro medel of myocardial stretch on the silicone sheet has demonstrated the up regulation of the "cardiac fetal genes", including beta-MHC, skeletal alpha-actin, and atrial natriuretic factor (ANF), which is known to be a hallmark of the altered gene expression in the hypertrophic heart. Silicones 54-62 natriuretic peptide A Homo sapiens 207-210 1389150-0 1992 Silicone spray as an aid for drying DNA sequencing gels. Silicones 0-8 activation induced cytidine deaminase Homo sapiens 21-24 8473987-4 1993 We have attempted to observe the variations in competitive adsorption of fibrinogen and albumin onto the polyetherurethane urea (PEUU) surface in the presence of external lubricant, such as calcium stearate and silicone fluid coating. Silicones 211-219 fibrinogen beta chain Homo sapiens 73-83 1512283-3 1992 The 50:50 mixed film of U-6 and silicone (U-6/sil) was prepared by roll-mixing of the noncured silicone and the U-6 solution followed by evaporation of the solvent and heat-curing at 70 degrees C. The tissue responses around implants were classified into four groups as follows: (A) tumor, (B) atypical cell proliferation accompanied by preneoplastic changes, (C) cell proliferation without preneoplastic changes, (D) no obvious responses. Silicones 32-40 STIL, centriolar assembly protein Rattus norvegicus 42-49 1512283-3 1992 The 50:50 mixed film of U-6 and silicone (U-6/sil) was prepared by roll-mixing of the noncured silicone and the U-6 solution followed by evaporation of the solvent and heat-curing at 70 degrees C. The tissue responses around implants were classified into four groups as follows: (A) tumor, (B) atypical cell proliferation accompanied by preneoplastic changes, (C) cell proliferation without preneoplastic changes, (D) no obvious responses. Silicones 95-103 STIL, centriolar assembly protein Rattus norvegicus 42-49 1378636-1 1992 Recent experimental studies using wound chambers (silicone tubes) sutured to the transected rat sciatic nerve or thigh muscle have shown an accumulation of plasma-containing fluid and the formation of a fibrin/fibronectin clot within the chambers during the early phase. Silicones 50-58 fibronectin 1 Rattus norvegicus 210-221 1280400-0 1992 Growth factor expression in normal and diabetic rats during peripheral nerve regeneration through silicone tubes. Silicones 98-106 myotrophin Rattus norvegicus 0-13 2113649-7 1990 In contrast, macrophages from silicone- and PVC-loaded animals spontaneously released high levels of IL 1 (median 21.8; range 10-36.7) and 94 (range 36-336) U per 10(6) cells respectively). Silicones 30-38 interleukin 1 alpha Homo sapiens 101-105 1940715-12 1991 Maintenance of increased progesterone levels after conceptus removal using silicone tubing implants significantly (P less than 0.05) reduced the peak of the premature prolactin surge to 79.7 +/- 18 micrograms/l at 05.00 h on day 20. Silicones 75-83 prolactin Rattus norvegicus 167-176 1811624-1 1991 This study was conducted to determine the effectiveness of a silicone disclosing medium, G-C Fit-Checker, as an aid in the improvement of marginal integrity. Silicones 61-69 activation induced cytidine deaminase Homo sapiens 112-115 1925086-3 1991 These results suggest that the Oculab Tono-Pen is an effective instrument with which to measure intraocular pressure in silicone-filled eye. Silicones 120-128 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 43-46 2354430-2 1990 The Du Pen epidural catheter (Davol, Inc.) a silicone-based tunneled catheter modeled after the Hickman central venous catheter, has provided a safe, reliable means of long-term administration of drugs to the epidural space in over 400 patients to date. Silicones 45-53 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 7-10 2313218-7 1990 Thus, of an initial group of rats given silicone elastomer implants containing 50, 500 or 1000 micrograms oestradiol in oil, plasma vasopressin concentrations were reduced after 7 days treatment with 1000 micrograms oestradiol implants in association with reduced plasma sodium concentrations. Silicones 40-48 arginine vasopressin Rattus norvegicus 132-143 2113649-8 1990 Following in vitro stimulation with bacterial lipopolysaccharide (LPS), peritoneal macrophages from silicone- and PVC-treated animals released large amounts of IL 1 (median 538 (range 359-2017) U and median 653 (range 326-1134) U per 10(6) cells, respectively) as compared to LPS-stimulated macrophages from control animals (median 332 (range 130-306) U per 10(6) cells]. Silicones 100-108 interleukin 1 alpha Homo sapiens 160-164 2113649-9 1990 Zymosan or LPS stimulation of splenic cells from silicone- and PVC-loaded animals also secreted increased quantities of IL 1 as compared to controls. Silicones 49-57 interleukin 1 alpha Homo sapiens 120-124 33771440-6 2021 RESULTS: Both conventional hydrogels (etafilcon A, omafilcon A) and two of the four silicone hydrogels tested (balafilcon A, comfilcon A), exhibited some uptake of IL-1beta, IL-8 or TNF-alpha (p < 0.05). Silicones 84-92 interleukin 1 alpha Homo sapiens 164-172 33771440-6 2021 RESULTS: Both conventional hydrogels (etafilcon A, omafilcon A) and two of the four silicone hydrogels tested (balafilcon A, comfilcon A), exhibited some uptake of IL-1beta, IL-8 or TNF-alpha (p < 0.05). Silicones 84-92 C-X-C motif chemokine ligand 8 Homo sapiens 174-178 33771440-6 2021 RESULTS: Both conventional hydrogels (etafilcon A, omafilcon A) and two of the four silicone hydrogels tested (balafilcon A, comfilcon A), exhibited some uptake of IL-1beta, IL-8 or TNF-alpha (p < 0.05). Silicones 84-92 tumor necrosis factor Homo sapiens 182-191 30252532-5 2019 We demonstrate that EC-derived MIF decreases PC contractility on 2-dimensional silicone substrates via reduction of phosphorylated myosin light chain. Silicones 79-87 macrophage migration inhibitory factor Homo sapiens 31-34 34959358-0 2021 Assessing the Effects of VEGF Releasing Microspheres on the Angiogenic and Foreign Body Response to a 3D Printed Silicone-Based Macroencapsulation Device. Silicones 113-121 vascular endothelial growth factor A Homo sapiens 25-29 25800359-0 2015 Low molecular weight silicones particularly facilitate human serum albumin denaturation. Silicones 21-30 albumin Homo sapiens 61-74 34814145-3 2021 METHODS: First, we adapted our previously described ex vivo strategy and evaluated the adhesion strength of different tissue glues, Histoacryl and Glubran2 , by bonding polytetrafluoroethylene or silicone encapsulated nitinol glue receptor to human FM. Silicones 197-205 fibromodulin Homo sapiens 250-252 34351614-6 2021 The EBF was experimentally measured by the ratio of dose at the upstream surface of the silicone to the same point without the presence of the lead shield. Silicones 88-96 EBF transcription factor 1 Homo sapiens 4-7 34451169-0 2021 Silicone Implants Immobilized with Interleukin-4 Promote the M2 Polarization of Macrophages and Inhibit the Formation of Fibrous Capsules. Silicones 0-8 interleukin 4 Rattus norvegicus 35-48 34850612-11 2021 Our technique got further verification, as we successfully determined the Cp with different Indian black ink concentrations, placed at the junction between the agar and silicone-based phantom layers. Silicones 169-177 ceruloplasmin Homo sapiens 74-76 34771180-8 2021 The effectiveness of the AS-1 product (obtained from oil refining waste) as a dispersant additive in silicone enamel has been proven. Silicones 101-109 prostaglandin D2 receptor Homo sapiens 25-29 34786070-0 2021 A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling. Silicones 8-16 mechanistic target of rapamycin kinase Homo sapiens 153-157 34408504-8 2021 The Broncho-Cath was replaced with a silicone double-lumen tube Human Broncho , which has more flexible bronchial segment and an increased marginal gap between the bronchial cuff and the tracheal lumen opening. Silicones 37-45 tubulin epsilon 1 Homo sapiens 59-63 34451169-5 2021 Surface wettability, nitrogen content, and atomic force microscopy data clearly showed the successful immobilization of IL-4 on the silicone implant. Silicones 132-140 interleukin 4 Rattus norvegicus 120-124 34451169-9 2021 These results suggest that macrophage phenotype modulation can effectively reduce inflammation and fibrous CC on a silicone implant conjugated with IL-4. Silicones 115-123 interleukin 4 Rattus norvegicus 148-152 34331870-1 2021 OBJECTIVE: To examine the difference in incidence of ocular hypertension (OHT) following the introduction of filtered anti-vascular endothelial growth factor (anti-VEGF) medication in silicone-free syringes. Silicones 184-192 vascular endothelial growth factor A Homo sapiens 123-157 34331870-1 2021 OBJECTIVE: To examine the difference in incidence of ocular hypertension (OHT) following the introduction of filtered anti-vascular endothelial growth factor (anti-VEGF) medication in silicone-free syringes. Silicones 184-192 vascular endothelial growth factor A Homo sapiens 164-168 34202198-7 2021 The experiments demonstrate that upon thermal aging at 125 C, the silicone-free TIM becomes hard, while silicone-based TIM remains viscoelastic, which indicates its wide applicability to higher temperature applications for a long time. Silicones 67-75 Rho guanine nucleotide exchange factor 5 Homo sapiens 81-84 34202198-7 2021 The experiments demonstrate that upon thermal aging at 125 C, the silicone-free TIM becomes hard, while silicone-based TIM remains viscoelastic, which indicates its wide applicability to higher temperature applications for a long time. Silicones 105-113 Rho guanine nucleotide exchange factor 5 Homo sapiens 120-123 34202198-8 2021 Though silicone-based TIM displays better mechanical and thermal properties at elevated temperatures, dielectric properties indicate low conductivity for silicone-free TIM, which makes it a better candidate for silicone-sensitive applications where higher electric insulation is desired. Silicones 7-15 Rho guanine nucleotide exchange factor 5 Homo sapiens 22-25 34202198-8 2021 Though silicone-based TIM displays better mechanical and thermal properties at elevated temperatures, dielectric properties indicate low conductivity for silicone-free TIM, which makes it a better candidate for silicone-sensitive applications where higher electric insulation is desired. Silicones 154-162 Rho guanine nucleotide exchange factor 5 Homo sapiens 168-171 34202198-8 2021 Though silicone-based TIM displays better mechanical and thermal properties at elevated temperatures, dielectric properties indicate low conductivity for silicone-free TIM, which makes it a better candidate for silicone-sensitive applications where higher electric insulation is desired. Silicones 211-219 Rho guanine nucleotide exchange factor 5 Homo sapiens 168-171 34201543-5 2021 In conclusion, albumin provided lubrication for silicone hydrogel contact lenses regardless of albumin concentrations, while albumin only acted as a lubricant for hydrogel contact under normal concentration. Silicones 48-56 albumin Homo sapiens 15-22 35231495-12 2022 Protein adsorption to silicone tubing is driven by a combination of electrostatic and hydrophobic interactions which is effectively shielded by PS20. Silicones 22-30 WAP four-disulfide core domain 1 Homo sapiens 144-148 34201543-0 2021 Albumin Acts as a Lubricant on the Surface of Hydrogel and Silicone Hydrogel Contact Lenses. Silicones 59-67 albumin Homo sapiens 0-7 34201543-2 2021 How tear albumin could affect the friction coefficient of silicone hydrogel and hydrogel contact lenses was analyzed by sliding a lens against a quartz glass in normal and extremely high concentration of albumin solution. Silicones 58-66 albumin Homo sapiens 9-16 34201543-4 2021 The results showed that the friction coefficient of tested contact lenses did not correspond to both the albumin deposition amount and surface roughness, but we proposed a model of how albumin might act as a lubricant on the surface of some hydrogel and silicone hydrogel contact lenses. Silicones 254-262 albumin Homo sapiens 185-192 34106774-4 2021 The newly developed Genii ostomy appliances (Trio Healthcare) use novel Sil2 Breathable Silicone Technology to provide secure, effective adhesion and manage moisture levels by replicating natural transepidermal water loss (TEWL). Silicones 88-96 trio Rho guanine nucleotide exchange factor Homo sapiens 45-49 34106775-9 2021 Trio Healthcare has introduced this technology with a range of silicone-based flange extenders and is working with the University of Bradford Centre for Skin Sciences on prototype silicone-based stoma appliance flanges designed to significantly reduce the incidence of peristomal skin complications, such as MARSI and MASD. Silicones 180-188 trio Rho guanine nucleotide exchange factor Homo sapiens 0-4 35549026-4 2022 Here, we devised oriented E-cadherin-coated soft silicone substrates with sub-kPa or few-kPa elasticity but with similar viscous moduli and found that E-cadherin adhesions differentially organize depending on the magnitude of epithelial cell-like elasticity. Silicones 49-57 cadherin 1 Homo sapiens 26-36 35549026-4 2022 Here, we devised oriented E-cadherin-coated soft silicone substrates with sub-kPa or few-kPa elasticity but with similar viscous moduli and found that E-cadherin adhesions differentially organize depending on the magnitude of epithelial cell-like elasticity. Silicones 49-57 cadherin 1 Homo sapiens 151-161 35576315-4 2022 We present a patient with a stable history of liquid injectable silicone (LIS) given 20 years prior who developed chronic periocular and facial hypersensitivity after undergoing microneedling at a medi-spa. Silicones 64-72 surfactant protein A1 Homo sapiens 202-205 35567088-2 2022 In this work, a series of novel silicone-containing polyamides (PA1212/Si12) were successfully synthesized from 1,12-dodecarboxylic acid (LA), 1,12-dodecarbondiamine (DMDA), and 1,3-bis (amino-propyl) tetramethyldisiloxane (BATS), via a one-pot melt polycondensation method in the absence of a catalyst. Silicones 32-40 sarcoglycan gamma Homo sapiens 167-171 35420622-5 2022 Moreover, the modified silicone rubber can maintain a stable superhydrophobic state in acid/alkali (pH = 2, 4, 6, 8, and 10) and thermal environments (50-90 C). Silicones 23-31 polyhomeotic homolog 2 Homo sapiens 100-123 35245647-7 2022 The best-performing respirator-dressing combination was the Trident respirator with dressing Mepilex Lite silicone foam (90.2% pass rate). Silicones 108-116 forkhead box M1 Homo sapiens 60-67 2773638-4 1989 The mean endothelial cell density was lower in the silicone eyes (2076 +/- 196 cells/mm2) as compared to the control fellow eyes (2738 +/- 86 cells/mm2) (P = 0.004). Silicones 51-59 PNMA family member 2 Homo sapiens 85-88 35332909-7 2022 Silicones modified with SMAs having longer tethers (m = 13 and 30) underwent rapid and substantial water-driven restructuring of PEO to the surface to form highly hydrophilic surfaces, especially as SMA concentration increased. Silicones 0-9 survival of motor neuron 1, telomeric Homo sapiens 199-202 35332909-10 2022 When the three SMAs were introduced at the highest concentration, modified silicones remained non-cytotoxic and LEC count and associated alpha-smooth muscle actin (alpha-SMA) expression decreased with increasing tether length. Silicones 75-84 actin alpha 1, skeletal muscle Homo sapiens 164-173 35420670-11 2022 CONCLUSIONS: VP reduced capsule formation after silicone implantation by inhibiting YAP1-mediated mechanical signaling, thereby attenuating excessive collagen deposition in the rabbit model. Silicones 48-56 transcriptional coactivator YAP1 Oryctolagus cuniculus 84-88 35404438-6 2022 Results: The mean alpha-SMA/S ratios of the SIBS and silicone groups were lower than that of the stainless-steel group at 4 weeks after surgery (P < 0.05), and that of the SIBS group was lower than that of the GACLC group (P < 0.05). Silicones 53-61 actin alpha 1, skeletal muscle Homo sapiens 18-27 35383709-0 2022 A 27-gauge trocar-assisted intrascleral intraocular lens fixation technique using a silicone microtube. Silicones 84-92 immunoglobulin kappa variable 3-20 Homo sapiens 0-4 34989448-4 2022 The surface is prepared by spray-coating silicone nanofilaments onto a pre-stretched substrate (e.g., cis-1,4-polyisoprene) with a polydimethylsiloxane (PDMS) layer as a binder. Silicones 41-49 suppressor of cytokine signaling 1 Homo sapiens 102-107 2753116-0 1989 Nerve growth factor enhances regeneration through silicone chambers. Silicones 50-58 nerve growth factor Rattus norvegicus 0-19 2773638-4 1989 The mean endothelial cell density was lower in the silicone eyes (2076 +/- 196 cells/mm2) as compared to the control fellow eyes (2738 +/- 86 cells/mm2) (P = 0.004). Silicones 51-59 PNMA family member 2 Homo sapiens 148-151 2489668-9 1989 Strain in compression of HEM, HEL, EPM, EPF was bigger than that of the traditional addition-type silicone impression materials. Silicones 98-106 heat shock protein family E (Hsp10) member 1 Homo sapiens 40-43 3196563-8 1988 Based on similar albumin affinities for biocompatible C18 alkylated and C16 acylated polyether polyurethanes, the authors expect significant improvements in thromboresistance and complement-activating potential for this modified silicone rubber. Silicones 229-237 Bardet-Biedl syndrome 9 Homo sapiens 54-57 3389038-4 1988 A MEP-containing silicone tube, releasing 245 nmol per 24 h in vitro, was implanted sc in the back of 25-day-old female rats. Silicones 17-25 neurolysin Rattus norvegicus 2-5 3389038-7 1988 However, implantation of a MEP-containing silicone tube under the skin or inserting a pellet containing MEP under the ovarian capsule did not result in advancement of the first ovulation. Silicones 42-50 neurolysin Rattus norvegicus 27-30 3657360-1 1987 A technique for achieving permanent middle ear aeration by inserting a flanged silicone tube (SPAT) through a hole drilled in the external auditory canal was introduced in 1970. Silicones 79-87 alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens 94-98 3144765-2 1988 A silicone piece coupled with anti-PAI-1 monoclonal antibody was incubated with human plasma or human plasma which had previously been incubated with t-PA in order to convert all the free PAI-1 to t-PA-PAI-1 complex. Silicones 2-10 chromosome 20 open reading frame 181 Homo sapiens 150-154 3144765-2 1988 A silicone piece coupled with anti-PAI-1 monoclonal antibody was incubated with human plasma or human plasma which had previously been incubated with t-PA in order to convert all the free PAI-1 to t-PA-PAI-1 complex. Silicones 2-10 serpin family E member 1 Homo sapiens 188-193 3144765-2 1988 A silicone piece coupled with anti-PAI-1 monoclonal antibody was incubated with human plasma or human plasma which had previously been incubated with t-PA in order to convert all the free PAI-1 to t-PA-PAI-1 complex. Silicones 2-10 chromosome 20 open reading frame 181 Homo sapiens 197-201 3144765-2 1988 A silicone piece coupled with anti-PAI-1 monoclonal antibody was incubated with human plasma or human plasma which had previously been incubated with t-PA in order to convert all the free PAI-1 to t-PA-PAI-1 complex. Silicones 2-10 serpin family E member 1 Homo sapiens 188-193 3144765-3 1988 After incubation, the amounts of t-PA bound on each silicone piece were measured by enzyme immunoassay. Silicones 52-60 chromosome 20 open reading frame 181 Homo sapiens 33-37 3144765-4 1988 The amounts of t-PA on a silicone piece incubated with plasma represent the amounts of t-PA-PAI-1 complex in the original plasma, and the amounts of t-PA on a silicone piece incubated with plasma previously added with t-PA represent total PAI-1 (the complex plus free PAI-1). Silicones 25-33 chromosome 20 open reading frame 181 Homo sapiens 15-19 3441295-2 1987 Nerve growth factor (NGF) administered at a single dose of 6000 Biological Units in silicone tubes fixed to the proximal nerve stump completely prevented these cell losses. Silicones 84-92 nerve growth factor Rattus norvegicus 0-19 3441295-2 1987 Nerve growth factor (NGF) administered at a single dose of 6000 Biological Units in silicone tubes fixed to the proximal nerve stump completely prevented these cell losses. Silicones 84-92 nerve growth factor Rattus norvegicus 21-24 3467880-6 1986 In mesangial cells grown on a flexible silicone rubber support, angiotensin II addition enhanced wrinkling of the mobile surface. Silicones 39-47 angiotensinogen Rattus norvegicus 64-78 3663806-4 1987 in human serum after incubation with and without IOLs for up to 12 h. The presence of silicone lenses caused an increase in C3a levels. Silicones 86-94 complement C3 Homo sapiens 124-127 3773553-2 1986 The cannula achieves a seal with the aortic wall through the use of bulbous silicone gel-filled tip. Silicones 76-84 TOR signaling pathway regulator Homo sapiens 96-99