PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
24496095-3	2014	Particularly, the central Mn(III) ion in MnCl(DPyP) was transmetallated with Co(II) or Zn(II) ions and the central Co(II) or Zn(II) ions were further coordinated to pyridyl groups of neighboring M(DPyP) (M = Co or Zn) porphyrin complexes.	mncl	41-45	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-83
24496095-3	2014	Particularly, the central Mn(III) ion in MnCl(DPyP) was transmetallated with Co(II) or Zn(II) ions and the central Co(II) or Zn(II) ions were further coordinated to pyridyl groups of neighboring M(DPyP) (M = Co or Zn) porphyrin complexes.	mncl	41-45	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	115-121
21107535-6	2011	Pre-treatment with tert-butylhydroquinone (tBHQ), a known agent that activates the Nrf2/ARE-HO-1 pathway, for 16 h prior to the 24 h MnCl(2) exposure attenuated both the cytotoxicity and the apoptosis induced by MnCl(2).	mncl	212-216	NFE2 like bZIP transcription factor 2	Rattus norvegicus	83-87
21699887-7	2011	RESULTS: An activation step consisting in prolidase incubation with 1 mmol/l MnCl(2) and 0.75 mmol/l reduced glutathione at 50 C for 20 min was necessary to obtain the maximum activity and to accurately determine, for the recombinant enzyme, V(max) (489 U/mg), K(m) (5.4 mM) and Mn(2+) affinity (54 mM(-1)).	mncl	77-81	peptidase D	Homo sapiens	42-51
17884722-12	2007	The expression of alkaline phosphatase (ALP) and collagen 1 (Col 1) mRNA decreased at >0.1mM MnCl(2).	mncl	96-100	alkaline phosphatase, placental	Homo sapiens	18-38
20868722-7	2011	Dug1p recognizes peptides in a metal independent manner and peptide binding is not sensitive to salts (dlogK/dlog[salt] ~ 0) over a range of [NaCl] (0.02-0.5 M), [ZnCl(2)], and [MnCl(2)] (0-0.5 mM).	mncl	178-182	metallodipeptidase	Saccharomyces cerevisiae S288C	0-5
21513697-7	2011	Increased levels of superoxide, as detected by DHE staining, were seen in vessels from TLR4(-/-) mice, which were reduced to control levels in the presence of MnCl(2).	mncl	159-163	toll-like receptor 4	Mus musculus	87-91
18775974-7	2008	Quantitative polymerase chain reaction showed that expression of AtCCX3 increased in plants treated with NaCl, KCl, and MnCl(2).	mncl	120-124	cation exchanger 9	Arabidopsis thaliana	65-71
17884722-12	2007	The expression of alkaline phosphatase (ALP) and collagen 1 (Col 1) mRNA decreased at >0.1mM MnCl(2).	mncl	96-100	alkaline phosphatase, placental	Homo sapiens	40-43
15530480-4	2004	RESULTS: Prolidase activity against glycylproline in erythrocytes from normal human was strongly enhanced by glycine, L-alanine, L-serine with MnCl(2), but the activity was strongly inhibited by L-valine, and L-leucine.	mncl	143-147	peptidase D	Homo sapiens	9-18
15703176-9	2005	Physiological analysis of this mutant revealed that the loss of hinT results in failure to grow in media containing 0.75 m KCl, 0.9 m NaCl, 0.5 m NaOAc, or 10 mm MnCl(2).	mncl	162-166	histidine triad nucleotide binding protein 1	Homo sapiens	64-68
15530480-8	2004	CONCLUSION: Prolidase activity against glycylproline in normal human erythrocytes and against methionylproline from the prolidase-deficient patient was enhanced strongly by glycine, alanine and serine with MnCl(2).	mncl	206-210	peptidase D	Homo sapiens	120-129
15530480-8	2004	CONCLUSION: Prolidase activity against glycylproline in normal human erythrocytes and against methionylproline from the prolidase-deficient patient was enhanced strongly by glycine, alanine and serine with MnCl(2).	mncl	206-210	peptidase D	Homo sapiens	12-21
12441642-3	2002	Temperature-sensitivity of mpc1-5 mutants was suppressed by 5 mM ZnSO(4) and by 5 mM MnCl(2).	mncl	85-89	pyruvate transporter MPC1	Saccharomyces cerevisiae S288C	27-33
15254256-9	2004	Amplifications in the presence of MnCl(2) indicate that position 1138 of the FGFR3 gene is particularly sensitive for mutations.	mncl	34-38	fibroblast growth factor receptor 3	Homo sapiens	77-82
15081893-3	2004	GA and EGCG showed inhibition with IC(50) of 60 and 700 nM, respectively, after pre-incubation with FucT VII in the presence of MnCl(2).	mncl	128-132	fucosyltransferase 7	Homo sapiens	100-108
10679794-1	2000	To evaluate the influence of transferrin (Tf) on manganese (Mn) uptake in the brain, pH 8.6 buffer-treated (54)MnCl(2), which has a higher affinity for Tf than untreated (54)MnCl(2), and Tf-bound (54)Mn were prepared.	mncl	111-115	transferrin	Rattus norvegicus	29-40
11467948-9	2001	Similar treatment of TNFR-IgG with alpha2,3ST and CMP-sialic acid (CMP-Sia), in the presence of MnCl(2), produced a molecule with an approximately 11% increase in the level of terminal sialylation but still contained oligosaccharides with terminal GlcNAc residues.	mncl	96-100	TNF receptor superfamily member 1A	Homo sapiens	21-25
11017771-8	2000	Rather, we found that polarized growth induced by mutations in CDC12 and CLA4 or by expression of excess SWE1 was also sensitive to EDTA treatment and was restored by the addition of MnCl(2) but not by the addition of CaCl(2).	mncl	183-187	septin CDC12	Saccharomyces cerevisiae S288C	63-68
11017771-8	2000	Rather, we found that polarized growth induced by mutations in CDC12 and CLA4 or by expression of excess SWE1 was also sensitive to EDTA treatment and was restored by the addition of MnCl(2) but not by the addition of CaCl(2).	mncl	183-187	serine/threonine protein kinase CLA4	Saccharomyces cerevisiae S288C	73-77
11017771-8	2000	Rather, we found that polarized growth induced by mutations in CDC12 and CLA4 or by expression of excess SWE1 was also sensitive to EDTA treatment and was restored by the addition of MnCl(2) but not by the addition of CaCl(2).	mncl	183-187	tyrosine protein kinase SWE1	Saccharomyces cerevisiae S288C	105-109
11821394-9	2002	The addition of MgCl(2) or MnCl(2), but not CaCl(2), further stimulated the dephosphorylation of NPR-A, and microcystin failed to inhibit this process.	mncl	27-31	natriuretic peptide receptor 1	Mus musculus	97-102
4365575-3	1974	In the presence of 10 mM MnCl(2), a half-maximal increase in phosphorylation of these proteins was achieved with 20-30 nM cyclic GMP.	mncl	25-29	5'-nucleotidase, cytosolic II	Homo sapiens	129-132
11666793-1	1996	A novel manganese(IV) monomer, [Mn(IV)(Me(3)TACN)(OMe)(3)](PF(6)), has been synthesized in methanol by the reaction of MnCl(2) with the ligand, N,N",N"-trimethyl-1,4,7-triazacyclononane (Me(3)TACN), in the presence of Na(2)O(2).	mncl	119-123	sperm associated antigen 17	Homo sapiens	59-64
31177709-6	2019	Compared with the control group, the expression of m-CTSD was significantly increased at the does of 0.125-0.25 mmol/L MnCl(2), while it was decreased at the does of 1.0 mmol/L (P<0.01) .	mncl	119-123	cathepsin D	Homo sapiens	53-57