PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21087929-4	2011	We measured the transposition of Ty1 in various genetic backgrounds and discovered that Tof1 suppressed excessive retromobility in collaboration with either Rrm3 or the F-box protein Dia2.	ty1	33-36	Tof1p	Saccharomyces cerevisiae S288C	88-92
19414561-8	2009	Overexpression of a cellular RNase H, which degrades RNA in an RNA:DNA hybrid, completely suppressed the increase in Ty1 multimer formation in an rrm3 mutant.	ty1	117-120	DNA helicase	Saccharomyces cerevisiae S288C	146-150
21092201-11	2010	In the presence of the dNTP reducing agent hydroxyurea at permissive temperatures, Ty1 mobility was stimulated in the wild type and sml1 deletion strains but not in the rfx1 deletion strain.	ty1	83-86	ribonucleotide reductase inhibiting protein SML1	Saccharomyces cerevisiae S288C	132-136
21092201-13	2010	Deletion of the S-phase checkpoint pathway Dun1 kinase, which inactivates Sml1 and Rfx1, reduced Ty1 mobility at a range of temperatures.	ty1	97-100	serine/threonine protein kinase DUN1	Saccharomyces cerevisiae S288C	43-47
21092201-13	2010	Deletion of the S-phase checkpoint pathway Dun1 kinase, which inactivates Sml1 and Rfx1, reduced Ty1 mobility at a range of temperatures.	ty1	97-100	ribonucleotide reductase inhibiting protein SML1	Saccharomyces cerevisiae S288C	74-78
21092201-13	2010	Deletion of the S-phase checkpoint pathway Dun1 kinase, which inactivates Sml1 and Rfx1, reduced Ty1 mobility at a range of temperatures.	ty1	97-100	Rfx1p	Saccharomyces cerevisiae S288C	83-87
15454529-6	2004	We speculate that the increase in recombination seen in sir4 mutants at high temperature may be due to changes in chromatin structure or Ty1 interactions with chromosomal structures resulting in higher recombination rates.	ty1	137-140	chromatin-silencing protein SIR4	Saccharomyces cerevisiae S288C	56-60
15833918-3	2005	ATP-dependent chromatin remodeling by Isw2 upstream of tRNA genes leads to changes in chromatin structure and Ty1 integration site selection.	ty1	110-113	DNA translocase	Saccharomyces cerevisiae S288C	38-42
15833918-4	2005	We show that the N terminus of Bdp1p, a component of the RNA polymerase III transcription factor TFIIIB, is required for periodic integration of Ty1 into the integration window.	ty1	145-148	transcription factor TFIIIB subunit BDP1	Saccharomyces cerevisiae S288C	31-36
9234690-4	1997	The Ste12p-dependent UAS from Ty1, called a sterile response element (SRE), is of the second type and is comprised of a PRE and an adjacent TEA (TEF-1, Tec1, and AbaA motif) DNA consensus sequence (TCS).	ty1	30-33	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	4-10
11983178-1	2002	Mutations in PMR1, a yeast gene encoding a calcium/manganese exporter, dramatically decrease Ty1 retrotransposition.	ty1	93-96	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	13-17
10655210-0	2000	The Saccharomyces cerevisiae DNA recombination and repair functions of the RAD52 epistasis group inhibit Ty1 transposition.	ty1	105-108	recombinase RAD52	Saccharomyces cerevisiae S288C	75-80
11463820-4	2001	Here, we demonstrate that Sgs1, a RecQ helicase required for genome stability, inhibits the mobility of Ty1 elements by a posttranslational mechanism.	ty1	104-107	ATP-dependent DNA helicase SGS1	Saccharomyces cerevisiae S288C	26-30
10101165-7	1999	Deletion of RAD6 was shown to alter the Ty1 target-site preference in the MET3-URA3 fusion and the LYS2 gene.	ty1	40-43	E2 ubiquitin-conjugating protein RAD6	Saccharomyces cerevisiae S288C	12-16
10101165-7	1999	Deletion of RAD6 was shown to alter the Ty1 target-site preference in the MET3-URA3 fusion and the LYS2 gene.	ty1	40-43	sulfate adenylyltransferase	Saccharomyces cerevisiae S288C	74-78
10101165-7	1999	Deletion of RAD6 was shown to alter the Ty1 target-site preference in the MET3-URA3 fusion and the LYS2 gene.	ty1	40-43	orotidine-5'-phosphate decarboxylase	Saccharomyces cerevisiae S288C	79-83
10101165-7	1999	Deletion of RAD6 was shown to alter the Ty1 target-site preference in the MET3-URA3 fusion and the LYS2 gene.	ty1	40-43	L-aminoadipate-semialdehyde dehydrogenase	Saccharomyces cerevisiae S288C	99-103
9234690-4	1997	The Ste12p-dependent UAS from Ty1, called a sterile response element (SRE), is of the second type and is comprised of a PRE and an adjacent TEA (TEF-1, Tec1, and AbaA motif) DNA consensus sequence (TCS).	ty1	30-33	translation elongation factor EF-1 alpha	Saccharomyces cerevisiae S288C	145-150
9234690-4	1997	The Ste12p-dependent UAS from Ty1, called a sterile response element (SRE), is of the second type and is comprised of a PRE and an adjacent TEA (TEF-1, Tec1, and AbaA motif) DNA consensus sequence (TCS).	ty1	30-33	Tec1p	Saccharomyces cerevisiae S288C	152-156
8849886-3	1996	A delta hta1-htb1 mutant with decreased levels of H2A and H2B histone proteins showed a pattern of Ty1 and Ty2 insertions at CAN1 that was significantly different from that of both the wild-type and a delta hta2-htb2 mutant, which does not have altered histone protein levels.	ty1	99-102	histone H2A	Saccharomyces cerevisiae S288C	8-12
9234728-9	1997	A 50-amino-acid region in the N terminus of the predicted Spt23p protein is necessary and sufficient for the transactivation and necessary for suppression of Ty1-induced mutations and the essential function of Spt23p.	ty1	158-161	Spt23p	Saccharomyces cerevisiae S288C	58-64
8849886-3	1996	A delta hta1-htb1 mutant with decreased levels of H2A and H2B histone proteins showed a pattern of Ty1 and Ty2 insertions at CAN1 that was significantly different from that of both the wild-type and a delta hta2-htb2 mutant, which does not have altered histone protein levels.	ty1	99-102	histone H2B	Saccharomyces cerevisiae S288C	13-17
8849886-3	1996	A delta hta1-htb1 mutant with decreased levels of H2A and H2B histone proteins showed a pattern of Ty1 and Ty2 insertions at CAN1 that was significantly different from that of both the wild-type and a delta hta2-htb2 mutant, which does not have altered histone protein levels.	ty1	99-102	arginine permease CAN1	Saccharomyces cerevisiae S288C	125-129
8596462-11	1995	In the viable npi1/rsp5 strain, expression of NPl1/RSP5 is reduced as a result of insertion of a Ty1 element in its 5" region.	ty1	97-100	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	14-18
8596462-11	1995	In the viable npi1/rsp5 strain, expression of NPl1/RSP5 is reduced as a result of insertion of a Ty1 element in its 5" region.	ty1	97-100	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	19-23
8596462-11	1995	In the viable npi1/rsp5 strain, expression of NPl1/RSP5 is reduced as a result of insertion of a Ty1 element in its 5" region.	ty1	97-100	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	51-55
8152932-3	1994	The binding site for the STE12 protein is located in the sterile responsive element (SRE), which is just downstream the 5" LTR of Ty1 and contains one copy of the pheromone response element (PRE).	ty1	130-133	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	25-30
7900422-2	1994	We have identified novel mutants, tye7, which are affected in Ty1-mediated expression of ADH2 through a Ty1 sequence distal to the 5" long terminal repeat sequence.	ty1	62-65	Tye7p	Saccharomyces cerevisiae S288C	34-38
7900422-2	1994	We have identified novel mutants, tye7, which are affected in Ty1-mediated expression of ADH2 through a Ty1 sequence distal to the 5" long terminal repeat sequence.	ty1	62-65	alcohol dehydrogenase ADH2	Saccharomyces cerevisiae S288C	89-93
7900422-9	1994	ADH2 activation by defined Ty1 derivatives revealed that TYE7 acts positively through the more distal Ty1 enhancer element (region D), and negatively in a region between A (the 5" proximal enhancer element) and D.	ty1	27-30	alcohol dehydrogenase ADH2	Saccharomyces cerevisiae S288C	0-4
7900422-9	1994	ADH2 activation by defined Ty1 derivatives revealed that TYE7 acts positively through the more distal Ty1 enhancer element (region D), and negatively in a region between A (the 5" proximal enhancer element) and D.	ty1	27-30	Tye7p	Saccharomyces cerevisiae S288C	57-61
2851719-4	1988	These native elements, Ty1-588 and Ty2-117, transposed at high levels when the GAL1 promoter was induced.	ty1	23-26	galactokinase	Saccharomyces cerevisiae S288C	79-83
32887876-5	2020	A cryo-electron microscopy structure of the bound complex at 2.9 A resolution reveals that Ty1 binds to an epitope on the RBD accessible in both the "up" and "down" conformations, sterically hindering RBD-ACE2 binding.	ty1	91-94	angiotensin converting enzyme 2	Homo sapiens	205-209
3036600-0	1987	A TY1 element is inserted in the CYR1 control region of Saccharomyces cerevisiae strain AB320.	ty1	2-5	adenylate cyclase	Saccharomyces cerevisiae S288C	33-37
6256080-5	1980	Cloning of the ROAM mutant gene CYC7-H2 shows that a 5.5 kb sequence homologous to a transposable and reiterated Ty1 element is inserted in the 5" noncoding region of the CYC7 structural locus.	ty1	113-116	cytochrome c isoform 2	Saccharomyces cerevisiae S288C	32-36
6256080-5	1980	Cloning of the ROAM mutant gene CYC7-H2 shows that a 5.5 kb sequence homologous to a transposable and reiterated Ty1 element is inserted in the 5" noncoding region of the CYC7 structural locus.	ty1	113-116	cytochrome c isoform 2	Saccharomyces cerevisiae S288C	171-175