PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
8801056-2	1996	The antifungal agent fluconazole was found to be a potent inhibitor of cytochrome P450 (P450) 2C9 (Ki = 7-8 microM), the principal enzyme responsible for the clearance (85%) of the more potent anticoagulant (S)-warfarin to the inactive (S)-7- and (S)-6-hydroxywarfarin metabolites in vivo.	6-hydroxywarfarin	247-268	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	71-97
22080016-7	2011	From the results of the inhibition assay, we finally suggest that aldehyde oxidase may mainly contribute to the warfarin alcohol products in chicken cytosol.	6-hydroxywarfarin	112-128	aldehyde oxidase 1	Gallus gallus	66-82
9526963-6	1997	The fluorine substituted warfarins and the S-warfarin alcohol apparently bind with high affinity to CYP2C9.	6-hydroxywarfarin	45-61	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	100-106
27055738-10	2016	Cytosol and AKR1C3 exhibit the stereoselective metabolism of (R)-warfarin to preferentially form (SR)-warfarin alcohol as the primary in vivo metabolite of warfarin.	6-hydroxywarfarin	102-118	aldo-keto reductase family 1 member C3	Homo sapiens	12-18