PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 34806333-3 2022 Among them, WY-5 is the most active MDM2 inhibitor with an IC50 value of 14.1 +- 2.8 nM. wy-5 12-16 MDM2 proto-oncogene Homo sapiens 36-40 34806333-4 2022 Moreover, WY-5 significantly up-regulate the protein level of p53 in SK-Hep-1 cells harboring wild-type p53. wy-5 10-14 tumor protein p53 Homo sapiens 62-65 34806333-4 2022 Moreover, WY-5 significantly up-regulate the protein level of p53 in SK-Hep-1 cells harboring wild-type p53. wy-5 10-14 tumor protein p53 Homo sapiens 104-107 34806333-7 2022 Our results demonstrate that WY-5 may be a promising candidate for the treatment of cancer which harboring wild-type p53. wy-5 29-33 transformation related protein 53, pseudogene Mus musculus 117-120